Mitophagy-regulated Necroptosis plays a vital role in the nephrotoxicity of Fumonisin B1 in vivo and in vitro
In conclusion, the RIPK1/RIPK3/MLKL signal route of necroptosis, which may be controlled by mitophagy, mediated nephrotoxicity of FB1. Our findings clarify the underlying molecular pathways of FB1-induced nephrotoxicity.PMID:38705344 | DOI:10.1016/j.fct.2024.114714 (Source: Food and Chemical Toxicology)
Source: Food and Chemical Toxicology - May 5, 2024 Category: Food Science Authors: Zhang Ping Zhang Shuxia Du Xinyu Huang Kehe Chen Xingxiang Wang Chunfeng Source Type: research
Carbon nanotubes integrated photonic barcodes in Herringbone Microfluidics for Multiplex Biomarker Quantification
In this study, we propose a novel herringbone microfluid chip with aptamer functionalized core-shell photonic crystal (PhC) barcode integration for high throughput multiplex CVD detection. Based on the PhC derived from co-assembled carboxylated single-wall carbon nanotubes and silicon dioxide nanoparticles, we obtain core-shell PhC barcodes by hydrogel replicating and partially etching. These core-shell PhC barcodes not only retain the original structural colors coding element, but also fully expose a large number of carboxyl elements in the ore for the probe immobilization. We further combine the functionalized barcodes w...
Source: Biosensors and Bioelectronics - May 5, 2024 Category: Biotechnology Authors: Xueqin Li Rui Liu Nan Zhang Junqi Zhao Yuanyang Zhou Qing Zhou Zhuxiao Gu Dagan Zhang Source Type: research
Unraveling the structure-chirality sensing relationship between achiral anthracene-based tetracationic nanotubes and nucleosides in aqueous host-guest complexation
This study provides insights for the construction of adaptive chirality from achiral nanotubes with dynamic conformational nature and might facilitate further design of chiral functional materials for several applications.PMID:38705071 | DOI:10.1016/j.bios.2024.116342 (Source: Biosensors and Bioelectronics)
Source: Biosensors and Bioelectronics - May 5, 2024 Category: Biotechnology Authors: Ting Yang Honghong Duan Hao Nian Pingxia Wang Chaochao Yan Fan Cao Qingfang Li Liping Cao Source Type: research
A forced aeration system for microbial culture of multiple shaken vessels suppresses volatilization
Arch Microbiol. 2024 May 5;206(6):246. doi: 10.1007/s00203-024-03960-2.ABSTRACTShake-flask culture, an aerobic submerged culture, has been used in various applications involving cell cultivation. However, it is not designed for forced aeration. Hence, this study aimed to develop a small-scale submerged shaking culture system enabling forced aeration into the medium. A forced aeration control system for multiple vessels allows shaking, suppresses volatilization, and is attachable externally to existing shaking tables. Using a specially developed plug, medium volatilization was reduced to less than 10%, even after 45 h of co...
Source: Archives of Microbiology - May 5, 2024 Category: Microbiology Authors: Masato Takahashi Yoshisuke Sawada Hideki Aoyagi Source Type: research
Unlocking the potential of SiO < sub > 2 < /sub > and CeO < sub > 2 < /sub > nanoparticles for arsenic mitigation in Vigna mungo L. Hepper (Blackgram)
In this study, the interaction effects of NaAsO2 (1 and 5 μM), SiO2 NPs (10 and 100 mg/L) and CeO2 NPs (10 and 100 mg/L) were assessed in Vigna mungo (Blackgram). The treatment of NaAsO2, SiO2, CeO2-NPs and combinations of NPs & As were applied to blackgram plants under hydroponic conditions. After its application, the morpho-physiological, antioxidant activity, and phytochemical study were evaluated. At 10 and 100 mg/L of SiO2 and CeO2-NPs, there was an increase in antioxidative enzymatic activity (p < 0.05) and reactive oxygen species (ROS). However, substantial ROS accumulation was observed at 1 and 5 μM NaAsO2...
Source: Environmental Science and Pollution Research International - May 5, 2024 Category: Environmental Health Authors: Vandita Anand Anjana Pandey Source Type: research
Construction and mechanistic insights of a novel ZnO functionalized rGO composite for efficient adsorption and reduction of Cr(VI)
Environ Sci Pollut Res Int. 2024 May 6. doi: 10.1007/s11356-024-33585-3. Online ahead of print.ABSTRACTA series of ZnO decorated reduced graphene oxide (rGO) (ZnrGOx) with different doping ratios were synthesized by the alkaline hydrothermal method using graphene oxide (GO) and Zn(NO3)2·6H2O as precursors, and subsequently used for the adsorption study of Cr(VI) in water. The morphology, crystalline phase structure, and surface elemental properties of ZnrGOx composites were revealed by XRD, SEM, BET, FT-IR, and XPS characterizations. The results showed that ZnO nanoparticles can be clearly seen on the surface of layered r...
Source: Environmental Science and Pollution Research International - May 5, 2024 Category: Environmental Health Authors: Haixia He Yanhui Cheng Siwei Qiu Lei Sun Bohua Jin Xiangjuan Yuan Source Type: research
Evaluation of radiation dose effect on lung function using iodine maps derived from dual-energy computed tomography
CONCLUSION: DECT derived iodine maps are a promising method for detailed anatomic evaluation of radiation effect on lung function, including potentially subclinical changes.PMID:38705488 | DOI:10.1016/j.ijrobp.2024.04.069 (Source: Physics in Medicine and Biology)
Source: Physics in Medicine and Biology - May 5, 2024 Category: Physics Authors: Shen Zhang Mika ël Simard Andr éanne Lapointe Édith Filion Marie-Pierre Campeau Thi Trinh Thuc Vu David Roberge Jean-Fran çois Carrier Danis Blais St éphane Bedwani Houda Bahig Source Type: research
Application of Recombinant Human Superoxide Dismutase in Radical Concurrent Chemoradiotherapy for Cervical Cancer to Prevent and Treat Radiation-induced Acute Rectal Injury: A Multi-center, Randomized, Open-label, Prospective Trial
CONCLUSION: The results of this study suggest that rhSOD enema is safe and significantly reduces the incidence, severity, and duration of RARI, protecting the rectal mucosa.PMID:38705489 | DOI:10.1016/j.ijrobp.2024.04.070 (Source: Health Physics)
Source: Health Physics - May 5, 2024 Category: Physics Authors: Jiawei Zhu Xiaofan Li Manni Huang Hong Zhu Yan Tan Xia He Zhihua Sun Huijun Cheng Fenghu Li Ping Jiang Hanmei Lou Guihao Ke Xinping Cao Lihong Zhu Peng Xie Junfang Yan Fuquan Zhang Source Type: research
Probe motion during mid-trimester fetal anomaly scan in the clinical setting: A prospective observational study
CONCLUSION: Some differences in the probe path metrics (velocity, acceleration, jerk and working volume) were noticed according to operator's level.PMID:38705008 | DOI:10.1016/j.ejogrb.2024.04.042 (Source: Reproductive Biology)
Source: Reproductive Biology - May 5, 2024 Category: Reproduction Medicine Authors: Maela Le Lous Francisco Vasconcelos Chiara Di Vece Brian Dromey Raffaele Napolitano Soojoeong Yoo Eddie Edwards Arnaud Huaulme Donald Peebles Danail Stoyanov Pierre Jannin Source Type: research
Patient-initiated follow-up in gynaecology: Patient and clinician views
CONCLUSIONS: In this study, both patients and clinicians are in favour of selected use of PIFU in gynaecology services. Both questionnaires found younger patients with benign gynaecological conditions were perceived as best suited PIFU. We recommend offering PIFU to select patients who are confident in self-monitoring, factoring patient choice so patients are not disadvantaged by this system. Further evaluation of PIFU in practice is needed before widespread implementation.PMID:38705009 | DOI:10.1016/j.ejogrb.2024.04.032 (Source: Reproductive Biology)
Source: Reproductive Biology - May 5, 2024 Category: Reproduction Medicine Authors: Mira Chainrai Victoria F Kershaw Thomas G Gray Stephen C Radley Source Type: research
Intermediate-risk endometrial cancer treated with adjuvant brachytherapy using single dosimetric planning: long-term outcome and toxicity assessment
CONCLUSION: These findings confirm the tolerability of this brachytherapy approach, indicating minimal cases of late grade ≥3 toxicity, associated with a good 5-year OS rate. With the advent of molecular prognostic factors, the current focus revolves around discerning those individuals who gain the greatest benefit from adjuvant therapy, and tailoring treatment more effectively.PMID:38705010 | DOI:10.1016/j.ejogrb.2024.04.040 (Source: Reproductive Biology)
Source: Reproductive Biology - May 5, 2024 Category: Reproduction Medicine Authors: Abel Cordoba El Hajj Houssein Alexandre Escande Cyrielle Scouarnec Fabrice Narducci Carlos Martinez Gomez Eric Leblanc Delphine Hudry Camille Pasquesoone Sophie Taieb Xavier Mirabel Eric F Lartigau Florence Le Tinier Source Type: research
Chromosomal abnormalities study for anembryonic pregnancy by BACs-on-Beads technique
CONCLUSION: The BoBs™ assay effectively detected diverse chromosomal abnormalities in villi samples from POC. The diagnostic utility of the BoBs™ assay was highlighted in identifying chromosomal irregularities in AP cases. Trisomy 16 possessed the most chromosomal abnormalities in the AP samples.PMID:38705011 | DOI:10.1016/j.ejogrb.2024.04.041 (Source: Reproductive Biology)
Source: Reproductive Biology - May 5, 2024 Category: Reproduction Medicine Authors: Preyaporn Onsod Watcharapa Jaranasaksakul Takol Chareonsirisuthigul Rachanee Parinayok Budsaba Rerkamnuaychoke Prapatsorn Areesirisuk Source Type: research
Surgical evacuation with intraoperative ultrasound (SEE U): A randomised controlled trial
CONCLUSIONS: This multicentre pilot study showed that a large RCT comparing surgical management of miscarriage with and without intraoperative ultrasound is feasible.PMID:38705012 | DOI:10.1016/j.ejogrb.2024.04.004 (Source: Reproductive Biology)
Source: Reproductive Biology - May 5, 2024 Category: Reproduction Medicine Authors: Paul P Smith Versha Cheed Lee Middleton Adam J Devall Feras Izzat T Justin Clark Source Type: research
Metritis and the uterine disease microbiome are associated with long-term changes in the endometrium of dairy cows †
Biol Reprod. 2024 May 5:ioae067. doi: 10.1093/biolre/ioae067. Online ahead of print.ABSTRACTCows with metritis (uterine disease) during the first 1 to 2 wk postpartum have lower pregnancy rates when inseminated later postpartum (typically >10 wk). We hypothesized that metritis and the disease-associated uterine microbiome have a long-term effect on endometrial gene expression. Changes in gene expression may inform a mechanism through which disease lowers pregnancy rates. A total of 20 cows were enrolled at 1 to 2 wk postpartum to either metritis (clinical disease; n = 10) or healthy (control; n = 10) groups and randomly...
Source: Reproductive Biology - May 5, 2024 Category: Reproduction Medicine Authors: Josiane C C Silva Monica O Caldeira Joao G N Moraes Isabella Sellmer Ramos Tamara Gull Aaron C Ericsson Scott E Poock Thomas E Spencer Matthew C Lucy Source Type: research
Choice and factors associated to the use of contraceptive methods among postpartum women: A prospective cohort study
CONCLUSION: Long-acting reversible contraception (LARC) methods were the most desired contraceptives among women after delivery. Providing and initiating free contraception prior to discharge from a birthing unit is important with regard to use of their desired method.PMID:38705006 | DOI:10.1016/j.ejogrb.2024.04.038 (Source: Reproductive Biology)
Source: Reproductive Biology - May 5, 2024 Category: Reproduction Medicine Authors: Elaine Meireles Castro Maia Raquel Autran Coelho Peixoto Cristina Aparecida Falbo Guazzelli Source Type: research
