Construction of deep learning-based convolutional neural network model for automatic detection of fluid hysteroscopic endometrial micropolyps in infertile women with chronic endometritis
CONCLUSION: These findings indicate that our deep learning-based CNN is capable of recognizing EMiP in F-HSC images and holds promise for further development of the computer-aided diagnostic system for CE.PMID:38703449 | DOI:10.1016/j.ejogrb.2024.04.026 (Source: Reproductive Biology)
Source: Reproductive Biology - May 4, 2024 Category: Reproduction Medicine Authors: Kotaro Kitaya Tadahiro Yasuo Takeshi Yamaguchi Yuko Morita Atsumi Hamazaki Shinji Murayama Takako Mihara Masaya Mihara Source Type: research

Organic fluorophores-based molecular probes with dual-fluorescence ratiometric responses to in-vitro/in-vivo pH for biosensing, bioimaging and biotherapeutics applications
Talanta. 2024 Apr 28;275:126171. doi: 10.1016/j.talanta.2024.126171. Online ahead of print.ABSTRACTIn recent years, organic fluorophores-based molecular probes with dual-fluorescence ratiometric responses to in-vitro/in-vivo pH (DFR-MPs-pH) have been attracting much interest in fundamental application research fields. More and more scientific publications have reported the exploration of various DFR-MPs-pH systems that have unique dual-fluorescence ratiometry as the signal output, in-built and signal self-calibration functions to improve precise detection of targets. DFR-MPs-pH systems possess high-performance applications...
Source: Talanta - May 4, 2024 Category: Chemistry Authors: Rijun Gui Hui Jin Source Type: research

A dual-mode label-free electrochemical immunosensor for ultrasensitive detection of procalcitonin by on-site vulcanization of dual-MOF heterostructure
Talanta. 2024 Apr 29;275:126186. doi: 10.1016/j.talanta.2024.126186. Online ahead of print.ABSTRACTDetection of procalcitonin (PCT) is crucial for the early identification of sepsis. PCT is primarily utilized in the multiple diagnosis of bacterial and viral illnesses along with to guide the application of antibiotics. Considering their advantages of high specificity and straightforward usage, electrochemical immunosensors offer significant application prospects in the detection of disease indicators. A dual-mode electrochemical immunosensor was constructed in this study to reliably identify PCT. In light of the synergistic...
Source: Talanta - May 4, 2024 Category: Chemistry Authors: Xin Wen Li Zhang Yangyang Wang Xiaojing Dong Yiqiang Sun Bo Xu Cuncheng Li Source Type: research

Detection of acetaminophen and P-aminophenol simultaneously by an electrochemical sensor based on Fe-NC derivatives attached with Ti < sub > 3 < /sub > C < sub > 2 < /sub > QDs
Talanta. 2024 May 1;275:126192. doi: 10.1016/j.talanta.2024.126192. Online ahead of print.ABSTRACTIn this paper, Ti3C2 QDs and Fe-ZIF-8 were synthesized by a straightforward hydrothermal method. Fe-ZIF-8 was pyrolyzed at high temperatures to obtain Fe-nanoclusters (Fe-NC). Then Fe-NC is mixed with Ti3C2 QDs to form a new composite material (Ti3C2 QDs/Fe-NC), and its microstructure and composition were analyzed by technology. The proposed material can detect acetaminophen (PA) and P-aminophenol (4-AP) simultaneously with excellent detection performance. With the best conditions, the linear ranges and detection limits were 0...
Source: Talanta - May 4, 2024 Category: Chemistry Authors: Jinjin Zhang Sumin Xu Wenjing Liu Qi Wang Jianying Qu Source Type: research

Decision-level data fusion based on laser-induced breakdown and Raman spectroscopy: A study of bimodal spectroscopy for diagnosis of lung cancer at different stages
This study provides a powerful new tool for the accurate staging and diagnosis of lung tumors.PMID:38703481 | DOI:10.1016/j.talanta.2024.126194 (Source: Talanta)
Source: Talanta - May 4, 2024 Category: Chemistry Authors: Jingjun Lin Yao Li Xiaomei Lin Changjin Che Source Type: research

Comparison of two carbonaceous supported Fe-rich adsorbents for arsenate removal: A functionalisation and mechanistic study with applicability to groundwater treatment
In this study, two iron-rich carbonous adsorbents were compared for the removal of arsenate (As(V)) from groundwater. Biochars (FeO-biochar and FeO-pyrochar) derived from biomass waste were functionalised in two different ways with iron chloride for comparation. Batch and dynamic parameters were optimised to achieve >99% As(V) removal efficiency. Experimental data best described by the pseudo-second order kinetic model, while multi-stage diffusion appeared to limit mass transfer of As(V). Among the isotherm models evaluated, the Freundlich model best described the experimental results with high correlation coefficients ...
Source: Chemosphere - May 4, 2024 Category: Chemistry Authors: Sabolc Pap Maja Turk Sekulic Hai Nguyen Tran Huan-Ping Chao Peter J Gilbert Stuart W Gibb Mark A Taggart Source Type: research

Interactions between methyl octabromo ether flame retardant and expandable polystyrene microplastics in the photoaging process
In this study, we simulated the photoaging process of flame retardant-added EPS (FR-EPS) and common original EPS (OR-EPS) microplastic (MP) particles with and without methyl octabromoether flame retardant (MOBE) in the laboratory to explore the effect of MOBE on the photodegradation of EPS. Results showed that MOBE accelerated size reduction and surface hole formation on the particles, hastening the shedding and replacement of particle surfaces. FR-EPS particles exhibited a weight loss exceeding that of OR-EPS, reaching 40.85 ± 3.72% after 36 days of irradiation. Moreover, rapid physical peeling of the FR-EPS surface was ...
Source: Chemosphere - May 4, 2024 Category: Chemistry Authors: Yanqi Shi Lezhou Zheng Hexinyue Huang Linping Shi Zhimin Gong Kefu Ye Xingqi Chen Shixiang Gao Source Type: research

Exposure to UV-B filter octylmethoxycinnamate and human health effects: focus on endocrine disruptor actions
This article aims to provide an overview of the UV filters' photoprotection, emphasizing the OMC and the possible negative effects it may have on the public health. Moreover, the current legislation will be addressed. In summary, the recommendations should be rethought to assess their risk-benefit, since the existing literature warns us to endocrine-disrupting effects of OMC. Further studies should be focus on the toxicity of OMC alone, in mixture and should consider its degradation products, to improve the knowledge of its risk assessment as EDC.PMID:38704047 | DOI:10.1016/j.chemosphere.2024.142218 (Source: Chemosphere)
Source: Chemosphere - May 4, 2024 Category: Chemistry Authors: Margarida Lorigo Carla Quintaneiro Luiza Breitenfeld Elisa Cairrao Source Type: research

Application of machine learning for antibiotic resistance in water and wastewater: A systematic review
Chemosphere. 2024 May 2:142223. doi: 10.1016/j.chemosphere.2024.142223. Online ahead of print.ABSTRACTAntibiotic resistance (AR) is considered one of the greatest global threats in the current century, which can only be overcome if all interconnected areas of humans, animals and the environment are taken into account as part of the One Health concept proposed by the World Health Organization (WHO). Water and wastewater are among the most important environmental media of AR sources, where the phenomena are generally non-linear. Therefore, the aim of this study was to investigate the application of machine learning-based met...
Source: Chemosphere - May 4, 2024 Category: Chemistry Authors: Maryam Foroughi Afrooz Arzehgar Seyedeh Nahid Seyedhasani Azam Nadali Khaled Zoroufchi Benis Source Type: research

Enhanced electrocatalytic removal of bisphenol A by introducing Co/N into precursor formed from phenolic resin waste
In this study, phenolic resin waste was utilized as a multi-carbon precursor for the electrocatalytic cathode and loaded with cobalt/nitrogen (Co/N) on its surface to form qualitative two-dimensional carbon nano-flakes (Co/NC). The onset potentials, half-wave potentials, and limiting current densities of the nitrogen-doped composite carbon material Co/NC in oxygen saturated 0.5 mol H2SO4 were -0.08 V, -0.61 V, and -0.41 mA·cm-2; and those of alkaline conditions were -0.65 V, -2.51 V, and -0.38 mA·cm-2, and the corresponding indexes were improved compared with those of blank titanium electrodes, which indicated that the c...
Source: Chemosphere - May 4, 2024 Category: Chemistry Authors: Chao Yin Xin He Xin Yang Chao Zeng Yuheng Feng Bin Xu Yulin Tang Source Type: research

Profiling population-wide exposure to environmental chemicals: A case study of naphthalene
Chemosphere. 2024 May 2:142217. doi: 10.1016/j.chemosphere.2024.142217. Online ahead of print.ABSTRACTLong-term exposure to environmental chemicals can detrimentally impact human health, and understanding the relationship between age distribution and levels of external and internal exposure is crucial. Nonetheless, existing methods for assessing population-wide exposure across age groups are limited. To bridge this research gap, we introduced a modeling approach designed to assess both chronic external and internal exposure to chemicals at the population level. The external and internal exposure assessments were quantified...
Source: Chemosphere - May 4, 2024 Category: Chemistry Authors: Xiaoyu Zhang Zijian Li Source Type: research

Glyphosate-environmental variables interaction: how does it affect the parasite Chordodes nobilii?
This study is the first to report the combined effects of glyphosate, temperature, pH and time on a freshwater animal. It demonstrates that a specific combination of factors determines the effect of glyphosate on a non-target organism. The potential use of C. nobilli as a bioindicator is discussed. In the context of global warming and considering that the behavioral manipulation of terrestrial hosts by gordiids can shape community structure and the energy flow through food webs, our results raise concerns about possible negative effects of climate change on host-parasite dynamics.PMID:38704040 | DOI:10.1016/j.chemosphere.2...
Source: Chemosphere - May 4, 2024 Category: Chemistry Authors: Cecilia Achiorno Graciela Minardi Source Type: research

Optimizing removal of antiretroviral drugs from tertiary wastewater using chlorination and AI-based prediction with response surface methodology
Sci Total Environ. 2024 May 2:172931. doi: 10.1016/j.scitotenv.2024.172931. Online ahead of print.ABSTRACTChemical and pharmaceutical chemicals found in water sources create substantial risks to human health and the environment. The presence of pharmaceutical contaminants in water can cause antibiotic resistance development, toxicity to aquatic organisms, and endocrine disruption. Hence, the elimination of chemicals and other contaminants from wastewater prior to its release is a burgeoning concern in the domains of engineering and science. The use of treatment technologies in wastewater treatment plants can remove pharmac...
Source: Anal Sci - May 4, 2024 Category: Chemistry Authors: Zhenhua Kang Lian Duan Sasan Zahmatkesh Source Type: research

Heterozygous RB1 mutation enhanced ATP production in human iPSC-derived retinal organoids
CONCLUSION: The study provides novel insights into the metabolic phenotype of heterozygous RB1 mutant suggesting dysregulation of energy metabolism and glycolytic pathways to be first step even before the changes in cellular proliferation or other phenotypic consequences ensue.PMID:38704498 | DOI:10.1007/s11033-024-09564-9 (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - May 4, 2024 Category: Molecular Biology Authors: Ambily Vincent Subramanian Krishnakumar Sowmya Parameswaran Source Type: research

Association of cigarette smoking with changes in macroeconomic conditions
This study uses data from the 1987-2022 Behavioral Risk Factor Surveillance System and state-level employment rates from the US Bureau of Labor Statistics to estimate the association between macroeconomic conditions and cigarette smoking. Our finding suggests a positive association, which constantly declined with time after the 2001 recession. We find that a one percentage point increase in the employment rate is associated with a 1.4% higher likelihood of smoking cigarettes in the overall sample but declined to 0.4% among cohorts surveyed from 2011 to 2022. We also find strong positive and heterogeneous associations among...
Source: Economics and Human Biology - May 4, 2024 Category: Biology Authors: Samuel Asare Source Type: research