Comparison of two carbonaceous supported Fe-rich adsorbents for arsenate removal: A functionalisation and mechanistic study with applicability to groundwater treatment
In this study, two iron-rich carbonous adsorbents were compared for the removal of arsenate (As(V)) from groundwater. Biochars (FeO-biochar and FeO-pyrochar) derived from biomass waste were functionalised in two different ways with iron chloride for comparation. Batch and dynamic parameters were optimised to achieve >99% As(V) removal efficiency. Experimental data best described by the pseudo-second order kinetic model, while multi-stage diffusion appeared to limit mass transfer of As(V). Among the isotherm models evaluated, the Freundlich model best described the experimental results with high correlation coefficients ...
Source: Chemosphere - May 4, 2024 Category: Chemistry Authors: Sabolc Pap Maja Turk Sekulic Hai Nguyen Tran Huan-Ping Chao Peter J Gilbert Stuart W Gibb Mark A Taggart Source Type: research
Pharmacokinetics and Pharmacodynamics of Standard Nerve Agent Medical Countermeasures in G öttingen Minipigs
Toxicol Lett. 2024 May 2:S0378-4274(24)00084-5. doi: 10.1016/j.toxlet.2024.04.014. Online ahead of print.ABSTRACTAnimal research continues to serve a critical role in the testing and development of medical countermeasures. The Göttingen minipig, developed for laboratory research, may provide many benefits for addressing research questions within chemical defense. Targeted development of the Göttingen minipig model could reduce reliance upon non-human primates, and improve study design, statistical power, and throughput to advance medical countermeasures for regulatory approval and fielding. In this vein, we completed fou...
Source: Toxicology Letters - May 4, 2024 Category: Toxicology Authors: Jeffrey L Langston Mark C Moffett M Ross Pennington Todd M Myers Source Type: research
Effects of crotamine in human prostate cancer cell line
Toxicon. 2024 May 2:107746. doi: 10.1016/j.toxicon.2024.107746. Online ahead of print.ABSTRACTOur study presents the anticancer potential of crotamine from Crotalus durissus terrificus in human prostate cancer cell line DU-145. Crotamine isolation was conducted through RP-FPLC, its molecular mass analyzed by MALDI-TOF was 4881.4 kDa, and N-terminal sequencing confirmed crotamine identity. Crotamine demonstrated no toxicity and did not inhibit migration in HUVEC cells. Although no cell death occurred in DU-145 cells, crotamine inhibited their migration. Thus, crotamine presented potential to be a prototype of anticancer dru...
Source: Toxicon - May 4, 2024 Category: Toxicology Authors: Jo ão Victor Alberghini-Dos-Santos Caroline Andolfato Sanchez Karla de Castro Figueiredo Bordon Manuela Berto Pucca Lus ânia Maria Greggi Antunes Eliane Candiani Arantes Isadora Sousa de Oliveira Source Type: research
Evaluation of the Toxicological Properties of Himantura imbricata Venom Using a Zebrafish Model (Danio rerio)
Toxicon. 2024 May 2:107739. doi: 10.1016/j.toxicon.2024.107739. Online ahead of print.ABSTRACTThe stingrays of the genus Himantura imbricata are present in all of the world's oceans, but the toxicity of their venoms has not yet been thoroughly characterized. The zebrafish as a toxicology model can be used for general toxicity testing of drugs and the investigation of toxicological mechanisms. The aim of this study was to evaluate the effect of crude venom from the stingray H. imbricata on the zebrafish Danio rerio. Juvenile zebrafish were injected with different concentrations of venom from H. imbricata via subcutaneous in...
Source: Toxicon - May 4, 2024 Category: Toxicology Authors: Uthra Selvaraj Sivaranjani Ganapathy None Arumugam Muthuvel Asha Monica Alex Javed Masood Khan Periyasamy Vijayalakshmi Source Type: research
Oligonucleotide-Based Photoaffinity Probes: Chemical Tools and Applications for Protein Labeling
Chembiochem. 2024 May 4:e202400097. doi: 10.1002/cbic.202400097. Online ahead of print.ABSTRACTA variety of proteins interact with DNA and RNA, including polymerases, histones, ribosomes, transcription factors, and repair enzymes. However, the transient non-covalent nature of these interactions poses challenges for analysis. Introducing a covalent bond between proteins and DNA via photochemical activation of a photosensitive functional group introduced onto nucleic acids offers a means to stabilize these often weak interactions without significantly altering the binding interface. Consequently, photoactivatable oligonucleo...
Source: Chembiochem - May 4, 2024 Category: Biochemistry Authors: Carole Saintom é Oc éane Monfret Gilles Doisneau Dominique Guianvarc'h Source Type: research
Down to Size: Exploring the Influence of Plastic Particle Dimensions on Physiological and Nervous Responses in Early-Stage Zebrafish
This study brings a straight approach to compare MPs and NPs, and assess their direct and indirect effects on zebrafish embryos and larvae. Zebrafish eggs were exposed before 2 h post fertilization (hpf) to polystyrene MPs (5 μm) and NPs (250 nm) at a concentration of 1000 μg L-1 until 96 hpf. Physiotoxicity and neurotoxicity were assessed prior and post-hatching through several biomarkers. Response to hypoxia (upregulation of hif-1aa and hif-1ab) were found in embryos exposed to MPs, and partly found in those exposed to NPs. Embryos exposed to NPs showed significant tachycardia, reduced O2 consumption and increased apop...
Source: Environmental Pollution - May 4, 2024 Category: Environmental Health Authors: Mathilde J L Oger Oc éane Vermeulen J érôme Lambert Thomas L Madanu Patrick Kestemont Val érie Cornet Source Type: research
Marine degradation and ecotoxicity of conventional, recycled and compostable plastic bags
In this study, we assess the degradation of commercially available plastic bags in marine conditions at two scales: aquariums (60 days) and outdoors flow-through mesocosm (120 days). Strength at break point and other tensile strength parameters were used as ecologically relevant endpoints to track mechanical degradation. Ecotoxicity has been assessed along the incubation period using the sensitive Paracentrotus lividus embryo test. Whereas PE bags did not substantially lose their mechanical properties within the 60 d aquarium exposures, compostable bags showed remarkable weight loss and tensile strength decay, some of them...
Source: Environmental Pollution - May 4, 2024 Category: Environmental Health Authors: Sara L ópez-Ibáñez Jakob Quade Angelika Wlodarczyk Mar ía-José Abad Ricardo Beiras Source Type: research
Inorganic UV filter-based sunscreens labelled as eco-friendly threaten sea urchin populations
Environ Pollut. 2024 May 2:124093. doi: 10.1016/j.envpol.2024.124093. Online ahead of print.ABSTRACTAlthough the negative effects of inorganic UV filters have been documented on several marine organisms, sunscreen products containing such filters are available in the market and proposed as eco-friendly substitutes for harmful, and already banned, organic UV filters (e.g. octinoxate and oxybenzone). In the present study, we investigated the effects of four sunscreen products, labelled by cosmetic companies as "eco-friendly", on the early developmental stages of the sea urchin Paracentrotus lividus, a keystone species occurr...
Source: Environmental Pollution - May 4, 2024 Category: Environmental Health Authors: F Marcellini S Varrella M Ghilardi G Barucca A Giorgetti R Danovaro C Corinaldesi Source Type: research
Long-Neglected Contribution of Nitrification to N < sub > 2 < /sub > O Emissions in the Yellow River
This study investigated the isotopic signatures of N2O, thereby quantifying the microbial source of N2O production and the degree of N2O reduction in the Yellow River. Although denitrification has long been considered to be the dominant pathway of N2O production in rivers, our findings indicated that denitrification only accounted for 18.3% (8.2%-43.0%) of the total contribution to N2O production in the Yellow River, with 50.2%-80.2% being concurrently reduced. The denitrification contribution to N2O production (R2 = 0.44, p < 0.01) and N2O reduction degree (R2 = 0.70, p < 0.01) were positively related to the dissolv...
Source: Environmental Pollution - May 4, 2024 Category: Environmental Health Authors: Shuo Wang Shengjie Li Mingfei Ji Jiarui Li Jilin Huang Zhengzhu Dang Zhuo Jiang Shuqi Zhang Xianfang Zhu Guodong Ji Source Type: research
The synergistic effect of typical chiral organic acids and solution chemistry conditions on the transport of 2-arylpropionic acid chiral derivatives in porous media
This study evaluated the transport of 2-arylpropionic acid derivatives enantiomers (2-APA) in porous media under a variety of solution chemistry conditions via column packing assays. The results revealed the introduction of Malic acid (MA) enantiomers enhanced the mobility of 2-APA enantiomers, but the enhancement effect was different for different 2-APA enantiomers. Batch sorption experiments confirmed that the MA enantiomers occupied the sorption site of the quartz sand, thus reducing the deposition of the 2-APA enantiomer. Homo- or heterochirality between 2-APA and MA dominates the transport of 2-APA enantiomers, with h...
Source: Environmental Pollution - May 4, 2024 Category: Environmental Health Authors: Duo Xu Yantian Ji Bowen Du Bo He Hongyang Chen Huimin Sun Xianqiang Yin Source Type: research
Reproductive and endocrine-disrupting toxicity of Pyrogallol in catfish (Clarias gariepinus)
Environ Pollut. 2024 May 2:124104. doi: 10.1016/j.envpol.2024.124104. Online ahead of print.ABSTRACTEndocrine disruptors are synthetic or natural chemicals that can agonize/antagonize hormone receptors or can interfere with the production and secretion of hormones, leading to altered tissue histology and physiology. Pyrogallol is a contaminant widely distributed in aquatic environments that presents health risks to both humans and animals. However, the potential for endocrine disruption by pyrogallol, particularly in fish, are lacking. The purpose of this study was to shed light on how pyrogallol may affect hormone signall...
Source: Environmental Pollution - May 4, 2024 Category: Environmental Health Authors: Mohamed Hamed Rashad E M Said Christopher J Martyniuk Hamdy A M Soliman Alaa El-Din H Sayed Alaa G M Osman Source Type: research
Association between long-term exposure to fine particulate matter and its chemical constituents and premature death in individuals living with HIV/AIDS
This study provides epidemiological evidence that SO42- and NH4+ increased the risk of ARD and that NH4+ increased the risk of ACD in PLWHA. Multi-constituent analyses further suggested that NH4+ may be a key component in increasing the risk of premature death in patients with HIV/AIDS. Individuals aged ≥65 with HIV/AIDS are more vulnerable to SO42-, and consequent ACD.PMID:38703976 | DOI:10.1016/j.envpol.2024.124052 (Source: Environmental Pollution)
Source: Environmental Pollution - May 4, 2024 Category: Environmental Health Authors: Shijie Zhu Faxue Zhang Xiaoxin Xie Wei Zhu Heng Tang Dingyuan Zhao Lianguo Ruan Dejia Li Source Type: research
Submerged plant-biochar composite system exhibits effective control over residual organic pollutants in the benthic organisms of aquaculture ponds
This study assesses a submerged plant-biochar system's efficacy in removing HOCs from simulated freshwater aquaculture ponds. Vallisneria natans was planted in sediment with varying levels of wheat straw biochar, while Corbicula fluminea served as the targeted benthic organism. The bioaccumulation experiment identified the optimal biochar ratio for the Vallisneria natans-biochar system in controlling HOCs in aquaculture products. Analyses included final accumulation concentrations in benthic organisms, changes in freely-dissolved concentrations in aquaculture sediment, and a mass balance calculation to explore key factors ...
Source: Environmental Pollution - May 4, 2024 Category: Environmental Health Authors: Juan-Ying Li Siyu Yao Zilong Mo Yabo Miao Yiqin Chen Wenhui He Ling Jin Wenzhong Tang Source Type: research
Retention of ZnO nanoparticles onto polypropylene and polystyrene microplastics: Aging-associated interactions and the role of aqueous chemistry
Environ Pollut. 2024 May 2:124097. doi: 10.1016/j.envpol.2024.124097. Online ahead of print.ABSTRACTMicroplastics (MPs) are pervasive and undergo environmental aging processes, which alters potential interaction with the co-contaminants. However, to assess their contaminant-carrying capacity, mimicking the weathering characteristics of secondary MPs is crucial. To this end, this study investigated the interaction of Zinc oxide (nZnO) nanoparticles with non-irradiated (NI) and UV-irradiated (UI) forms of the most abundant MPs in aqueous environments such as polypropylene (PP) and polystyrene (PS). SEM images revealed mechan...
Source: Environmental Pollution - May 4, 2024 Category: Environmental Health Authors: Jayant Karwadiya Johannes L ützenkirchen Gopala Krishna Darbha Source Type: research
Seasonal variations and sources of atmospheric EPFRs in a megacity in severe cold region: implications for the influence of strong coal and biomass combustion
In this study, the seasonal variations and sources of EPFRs in a severe cold region in Northeastern China were comprehensively investigated, especially for the high pollution events. The geomean concentration of EPFRs in the total suspended particle was 6.58×1013 spins/m3 and the mean level in winter was one order of magnitude higher than other seasons. The correlation network analysis showed that EPFRs had significantly positive correlation with carbon component, K+ and PAHs, indicating that EPFRs were primarily emitted from combustion and pyrolysis process. The source appointment by the Positive Matrix Factorization (PM...
Source: Environmental Research - May 4, 2024 Category: Environmental Health Authors: Shi-Ming Jia Mei-Hong Chen Pu-Fei Yang Liang Wang Guo-Ying Wang Li-Yan Liu Wan-Li Ma Source Type: research
