SARS-CoV-2 immunity and reasons for non-vaccination among healthcare workers from eastern and northern Switzerland: results from a nested multicentre cross-sectional study
CONCLUSIONS: Almost all healthcare workers in our cohort had specific antibodies against SARS-CoV-2 from natural infection and/or from vaccination. Young healthcare workers and those working in non-acute settings were less likely to be vaccinated, whereas physicians and administrative staff showed higher vaccination uptake. Presumed ineffectiveness of the vaccine is an important reason for non-vaccination.PMID:38689545 | DOI:10.57187/s.3734 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - May 1, 2024 Category: General Medicine Authors: Selina Albrecht Fabian Gr ässli Alexia Cusini Angela Brucher Stephan Goppel Elsbeth Betschon J Carsten M öller Manuela Ortner Markus Ruetti Reto Stocker Danielle Vuichard-Gysin Ulrike Besold Lorenz Risch Matthias Von Kietzell Matthias Schlegel Pietro Ve Source Type: research

Relevance of Emotion of Anxiety and Fear of Dentistry as Motivational Conflict in Oral Health Behaviors
CONCLUSION: Anxiety and fear of dentistry are not found to influence personal preventive oral care with reference to oral hygiene habits. Avoidance of dentistry factor of DFS is positively correlated with oral health behavior. Dental fear and anxiety do not impact oral health behaviors adversely.CLINICAL SIGNIFICANCE: In this era of youth and beauty, the utilization of professional dental care services is not affected by fear of invasive nature of dental procedures. Establishing the groundwork for knowledge regarding the scope of fear appeals in anxiety for dentistry may help to augment positive oral health behaviors for e...
Source: J Contemp Dent Pract - May 1, 2024 Category: Dentistry Authors: None Supriya Rajbir Singh Amra Ahsan Source Type: research

Elevated cardiovascular risk and acute events in hospitalized colon cancer survivors: A decade-apart study of two nationwide cohorts
CONCLUSION: Colon cancer survivors hospitalized 10 years apart in the United States showed an increased CVD risk with an increased risk of acute cardiovascular events (stroke 28%, PE 47%, arrhythmia 41%, and cardiac arrest 63%). It is vital to regularly screen colon cancer survivors with concomitant CVD risk factors to curtail long-term cardiovascular complications.PMID:38689632 | PMC:PMC11056864 | DOI:10.5306/wjco.v15.i4.548 (Source: Clinical Colorectal Cancer)
Source: Clinical Colorectal Cancer - May 1, 2024 Category: Cancer & Oncology Authors: Rupak Desai Avilash Mondal Vivek Patel Sandeep Singh Shaylika Chauhan Akhil Jain Source Type: research

The effects of alcohol use on smoking cessation treatment with nicotine replacement therapy: An observational study
CONCLUSION: Heavy, hazardous alcohol use is associated with lower odds of successfully quitting smoking compared to low or non-use of alcohol. Targeting alcohol treatment to this group may improve tobacco cessation outcomes.PMID:38692071 | DOI:10.1016/j.addbeh.2024.108045 (Source: Addictive Behaviors)
Source: Addictive Behaviors - May 1, 2024 Category: Addiction Authors: Benjamin K C Wong Scott Veldhuizen Nadia Minian Laurie Zawertailo Peter Selby Source Type: research

Evidence-based screening, clinical care and health education recommendations for Alaska Native peoples with prediabetes living in southcentral Alaska: findings from the Alaska EARTH follow-up study
This study investigated how much of the recent increase in pre-DM identified among Alaska Native (AN) peoples living in urban southcentral Alaska may be due to changes in diagnostic methods. We used clinical and demographic data collected at baseline between 2004 and 2006 and at follow-up collected between 2015 and 2017 from the urban southcentral Alaska Education and Research Towards Health (EARTH) cohort. We used descriptive statistics and logistic regression to explore differences in demographic and clinical variables among the identified pre-DM groups. Of 388 participants in the follow-up study, 243 had A1c levels indi...
Source: International Journal of Circumpolar Health - May 1, 2024 Category: International Medicine & Public Health Authors: Kathryn R Koller Sarah H Nash Julie A Beans Gretchen M Day Vanessa Y Hiratsuka Ai-Ling Lin Meera Narayanan Christi A Patten Sherry A Hammock Barbara V Howard Jason G Umans Source Type: research

The Impact of Rheumatoid Arthritis on First Nations and How We Can Work With Communities to Prevent It
J Rheumatol. 2024 May 1:jrheum.2024-0369. doi: 10.3899/jrheum.2024-0369. Online ahead of print.ABSTRACTRheumatoid arthritis (RA) is prevalent in many Indigenous North American First Nations (FN) and tends to be seropositive, familial, and disabling, as well as associated with highly unfavorable outcomes such as early mortality. The risk of developing RA is based on a perfect storm of gene-environment interactions underpinning this risk. The gene-environment interactions include a high frequency of shared epitope encoding HLA alleles, particularly HLA-DRB1*1402, in the background population, and prevalent predisposing envir...
Source: Journal of Rheumatology - May 1, 2024 Category: Rheumatology Authors: Hani El-Gabalawy Source Type: research

Circulating interleukin 17A and other inflammatory proteins may predict cardiovascular disease in early rheumatoid arthritis
CONCLUSION: Circulating IL-17A at RA diagnosis predicted future CVD, although we cannot exclude that this finding is due to multiple testing. The association was independent of traditional CVD risk factors, and of ESR at the time of diagnosis. Furthermore, OPG may be a predictor of CVD. We also identified some novel potential biomarkers for CVD in RA.PMID:38692670 | DOI:10.3899/jrheum.2023-1078 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 1, 2024 Category: Rheumatology Authors: Emil Rydell Lennart T H Jacobsson Carl Turesson Source Type: research

Genetic and Lifestyle Risk Factors of Metabolic Dysfunction-Associated Fatty Liver Disease and Its Relationship with Premature Coronary Artery Disease: A Study on the Pars Cohort
CONCLUSION: Our study found that consuming opium decreases the likelihood of MAFLD in CAD patients, since these patients have decreased appetite and lower body mass index (BMI). On the other hand, female gender, having diabetes, high waist circumference, high triglyceride levels, and high ALT levels increase the probability of MAFLD in CAD patients.PMID:38690791 | DOI:10.34172/aim.2024.36 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - May 1, 2024 Category: Middle East Health Authors: Amir Anushiravani Maryam Rayatpisheh Amir Kasaeian Iman Menbari Oskouie Source Type: research

Effectiveness of Applying Green Heart, a Smartphone-Based Self-management Intervention to Control Smoking: A Randomized Clinical Trial
CONCLUSION: Our results confirmed that complete adherence to the app for at least 24 weeks was linked to alterations in cigarette smoking behavior among CAD patients. Trial Registration Number: IRCT20221016056204N1.PMID:38690792 | DOI:10.34172/aim.2024.37 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - May 1, 2024 Category: Middle East Health Authors: Mojgan Ghavami Alireza Abdshah Ayat Ahmadi Diba Akbarzadeh Ali Mofidi Mahnaz Ashoorkhani Saeed Sadeghian Source Type: research

Identifying Risk Indicators of Cardiovascular Disease in Fasa Cohort Study (FACS): An Application of Generalized Linear Mixed-Model Tree
CONCLUSION: Given the superior performance of the GLMM tree compared with the standard tree and the lack of significant difference with the GLMM, using this model is suggested due to its simpler interpretation and fewer assumptions. Using updated statistical models for more accurate CVD prediction can result in more precise frameworks to aid in proactive patient detection planning.PMID:38690790 | DOI:10.34172/aim.2024.35 (Source: Archives of Iranian Medicine)
Source: Archives of Iranian Medicine - May 1, 2024 Category: Middle East Health Authors: Fariba Asadi Reza Homayounfar Mojtaba Farjam Yaser Mehrali Fatemeh Masaebi Farid Zayeri Source Type: research

SARS-CoV-2 immunity and reasons for non-vaccination among healthcare workers from eastern and northern Switzerland: results from a nested multicentre cross-sectional study
CONCLUSIONS: Almost all healthcare workers in our cohort had specific antibodies against SARS-CoV-2 from natural infection and/or from vaccination. Young healthcare workers and those working in non-acute settings were less likely to be vaccinated, whereas physicians and administrative staff showed higher vaccination uptake. Presumed ineffectiveness of the vaccine is an important reason for non-vaccination.PMID:38689545 | DOI:10.57187/s.3734 (Source: Swiss Medical Weekly)
Source: Swiss Medical Weekly - May 1, 2024 Category: General Medicine Authors: Selina Albrecht Fabian Gr ässli Alexia Cusini Angela Brucher Stephan Goppel Elsbeth Betschon J Carsten M öller Manuela Ortner Markus Ruetti Reto Stocker Danielle Vuichard-Gysin Ulrike Besold Lorenz Risch Matthias Von Kietzell Matthias Schlegel Pietro Ve Source Type: research

Circulating interleukin 17A and other inflammatory proteins may predict cardiovascular disease in early rheumatoid arthritis
CONCLUSION: Circulating IL-17A at RA diagnosis predicted future CVD, although we cannot exclude that this finding is due to multiple testing. The association was independent of traditional CVD risk factors, and of ESR at the time of diagnosis. Furthermore, OPG may be a predictor of CVD. We also identified some novel potential biomarkers for CVD in RA.PMID:38692670 | DOI:10.3899/jrheum.2023-1078 (Source: J Rheumatol)
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Emil Rydell Lennart T H Jacobsson Carl Turesson Source Type: research

The Impact of Rheumatoid Arthritis on First Nations and How We Can Work With Communities to Prevent It
J Rheumatol. 2024 May 1:jrheum.2024-0369. doi: 10.3899/jrheum.2024-0369. Online ahead of print.ABSTRACTRheumatoid arthritis (RA) is prevalent in many Indigenous North American First Nations (FN) and tends to be seropositive, familial, and disabling, as well as associated with highly unfavorable outcomes such as early mortality. The risk of developing RA is based on a perfect storm of gene-environment interactions underpinning this risk. The gene-environment interactions include a high frequency of shared epitope encoding HLA alleles, particularly HLA-DRB1*1402, in the background population, and prevalent predisposing envir...
Source: J Rheumatol - May 1, 2024 Category: Rheumatology Authors: Hani El-Gabalawy Source Type: research

Microsurgical limb reconstruction in the non-concordant patient
J Plast Reconstr Aesthet Surg. 2024 Apr 16;93:140-142. doi: 10.1016/j.bjps.2024.04.039. Online ahead of print.ABSTRACTSubstance misuse is common in patients undergoing limb reconstruction secondary to open fractures and fracture related infection. This group risk breaching the social contract with their treating team through reduced engagement with perioperative care. Potential problems include limited social support, intravenous access, analgesia and withdrawal. These factors may negatively influence the range of treatments offered to this group. We aimed to establish the prevalence and outcomes of the problematically non...
Source: Hand Surgery - May 1, 2024 Category: Surgery Authors: P Jageer J Kiely S Day C West W Bhat Source Type: research

Risk factors for asthma-related hospital and intensive care admissions in children, adolescents and adults: a cohort study using primary and secondary care data
CONCLUSIONS: There are significant sociodemographic inequalities in the rates of asthma-related hospital and ICU admissions. Treating age-specific modifiable risk factors should be considered an integral part of asthma management, which could potentially reduce the rate of avoidable hospital admissions.PMID:38692709 | DOI:10.1136/bmjresp-2023-001746 (Source: Respiratory Care)
Source: Respiratory Care - May 1, 2024 Category: Respiratory Medicine Authors: Nikita Simms-Williams Prasad Nagakumar Rasiah Thayakaran Nicola J Adderley Richard Hotham Adel H Mansur Krishnarajah Nirantharakumar Shamil Haroon Source Type: research