Insufficient use of corticosteroids without immunosuppressants results in higher relapse in Takayasu arteritis.
CONCLUSION: A higher dose of PSL was associated with a significant decrease in the relapse rate. The effect of combination therapy on relapse needs to be further investigated. Lower-dose PSL monotherapy is an undesirable strategy for remission induction in TAK, despite low disease activity. PMID: 31092708 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Developing a Preliminary Definition and Domains of Flare in Knee and Hip Osteoarthritis (OA): Consensus Building of the Flare-in-OA OMERACT Group.
Authors: Guillemin F, Ricatte C, Barcenilla-Wong A, Schoumacker A, Cross M, Alleyrat C, Buttel T, Cembalo M, Manseur H, Urban H, Fautrel B, Conaghan PG, Hawker G, Rutherford C, March L, Spitz E, Hunter DJ Abstract Flare in knee and hip osteoarthritis (OA) is more than just an exacerbation of pain. Unstructured, semistructured, and focus group interviews followed by Delphi surveys with patients and health professionals (HP) generated candidate domains of an OA flare. Content analysis of interviews with 29 patients and 16 HP extracted 180 statements, which were grouped into 9 clusters. Delphi consensus with 50 patien...
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Development and Validation of a microRNA Panel to Differentiate between Patients with Rheumatoid Arthritis or Systemic Lupus Erythematosus and Controls.
CONCLUSION: A miRNA panel identified by a bioinformatic approach differentiated between RA or SLE patients and control subjects. The panel may represent an autoimmunity signature, perhaps related to inflammatory arthritis, which is not dependent on active disease or seropositivity. PMID: 31092710 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Systemic Sclerosis after Bone Marrow Transplantation: A Case with Evidence of Donor-related Disease Transfer.
Authors: Silva Riveiro A, Nieto González JC, Martínez Barrio J Abstract A 34-year-old man was diagnosed in January 2002 with acute B lymphoblastic leukemia. After induction chemotherapy with vincristine and daunorubicin, complete remission was achieved. In October 2011 a bone marrow relapse was detected. He was treated with clofarabine, attaining morphological remission with minimal residual disease, and in February 2012 he received a haplo-identical allogeneic bone marrow transplantation (BMT) from his mother, achieving a second complete remission. PMID: 31092711 [PubMed - as supplied by publishe...
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Improving scoring precision and internal construct validity of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) using Rasch Measurement Theory.
CONCLUSION: Applying the Rasch transformed scores simplifies completion and scoring of the measure and confirms internal construct validity. It also ensures linear measurement and justifies the use of parametric statistical analyses when analysing datasets. The transformation table can be used with existing BASDAI datasets to allow direct comparisons of disease activity scores with those generated from future studies. PMID: 31092712 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Neutrophil Extracellular Traps (NETs) profiles in patients with incident SLE and lupus nephritis.
CONCLUSION: iLN patients have increased circulating NETs and reduced DNase activity, the later being explained by the presence of inhibitory substances in circulation and/or by rare DNase1L3 mutations. Accumulation of NETs derives from a multi-factorial mechanism, is associated and may contribute to disease severity in SLE, in particular to renal lesions. PMID: 31092713 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Thirty Years of Followup in 3 Patients with Familial Polyarteritis Nodosa due to Adenosine Deaminase 2 Deficiency.
Authors: Liebowitz J, Hellmann DB, Schnappauf O Abstract Three sisters of Northern European descent provided an opportunity to examine the longterm course and possible familial aspects of a rare disease, polyarteritis nodosa (PAN). Approval and consent was obtained from each patient. PMID: 31092714 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Multimorbidity is Common in Axial Spondyloarthropathy and is Associated with Worse Disease Outcomes: Results from the ASRI cohort.
This study aims to describe the prevalence of multimorbidity in axial spondyloarthropathy (axSpA) and assess its association with disease outcome measures. METHODS: This cross-sectional study was conducted within the Ankylosing Spondylitis Registry of Ireland (ASRI) cohort. Structured standardised assessment was performed. Multimorbidity was considered as the presence of at least 1 physician-diagnosed chronic condition (excluding extra-articular manifestations) in addition to axSpA. Validated outcome measures were collected: Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath AS Functional Index (BASFI), ...
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Pulmonary Artery Involvement in Patients with Takayasu Arteritis.
This study was performed to explore the clinical manifestations and long-term prognosis in patients with Takayasu arteritis (TA) with pulmonary artery involvement (PAI). METHODS: The medical records of 194 patients with TA who underwent traditional catheter angiography or computed tomography of pulmonary artery from 2009 to 2016 were retrospectively reviewed. The clinical manifestations, angiographic features, and mortality of 128 patients with TA with PAI were further analyzed. RESULTS: Patients with TA with PAI had a higher risk of pulmonary hypertension (PH) than patients with TA alone (61.7% vs. 7.6%, p
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Sj ögren's Syndrome without focal lymphocytic infiltration of the salivary glands.
CONCLUSION: There are only a few clinical differences between primary Sjögren's syndrome patients with focus score zero and those with both anti-Ro and a focus score>1.0. Nonetheless, the small subset of focus score zero patients tested did not have elevated expression of interferon-regulated genes, but did have systemic disease. Thus, extra-glandular manifestations are perhaps more related to the presence of anti-Ro than increased interferon. This may have relevance to Sjögren's syndrome pathogenesis. PMID: 31092717 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Clinical Significance of Serum Chitotriosidase Level in Anti-MDA5 Antibody-positive Dermatomyositis-associated Interstitial Lung Disease.
Authors: Fujisawa T, Hozumi H, Yasui H, Suzuki Y, Karayama M, Furuhashi K, Enomoto N, Nakamura Y, Inui N, Suda T Abstract OBJECTIVE: To assess prognostic factors of antimelanoma differentiation-associated gene 5 antibody (anti-MDA5)-positive dermatomyositis/clinically amyopathic DM-associated interstitial lung disease (DM/CADM-ILD) and evaluate the use of serum chitotriosidase, a marker for macrophage activation, as a potential biomarker in anti-MDA5-positive DM/CADM-ILD. METHODS: This retrospective study included 30 patients with anti-MDA5-positive DM/CADM-ILD. The clinical characteristics and laboratory findi...
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Thyroid Dysfunction in Patients with Antineutrophil Cytoplasmic Antibody-associated Vasculitis: A Monocentric Retrospective Study.
Authors: Kim JY, Park YB, Lee SW Abstract Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is characterized by necrotizing vasculitis in small-sized vessels such as arterioles, capillaries, and venules1 The possibility of a link between thyroid dysfunction and autoimmunity has been considered and its prevalence was reported differently according to each autoimmune disease2. PMID: 31092719 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Demographic, Clinical, and Immunologic Correlates among a Cohort of 50 Cocaine Users Demonstrating Antineutrophil Cytoplasmic Antibodies.
CONCLUSION: We identify sex and race as important risk modifiers in the developing CLAAS among cocaine users. The development of C-ANCA was associated with increased mortality. Moreover, we confirm the enriched presence of anti-MPO/anti-PR3 dual reactivity in CLAAS, further supporting the diagnostic utility of this feature. PMID: 31092720 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Cardiovascular Event Risk in Rheumatoid Arthritis is Higher than in Type 2 Diabetes: a 15 Year Longitudinal Study.
Authors: Agca R, Hopman LHGA, Laan KCJ, van Halm VP, Peters MJL, Smulders YM, Dekker JM, Nijpels G, Stehouwer CDA, Voskuyl AE, Boers M, Lems WF, Nurmohamed MT Abstract OBJECTIVE: Cardiovascular (CV) disease risk is increased in rheumatoid arthritis (RA). However, longterm follow-up studies investigating this risk are scarce. METHODS: CARRÉ is a prospective cohort study investigating CV disease and its risk factors in 353 patients with longstanding RA. CV endpoints were assessed at baseline, 3, 10 and 15 years after the start of the study and are compared to a reference cohort(n=2540) including a large nu...
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Ultrasonographic evidence of predominance of acute extracapsular and chronic intrasynovial patterns in 100 psoriatic hand dactylitis.
Authors: Girolimetto N, Macchioni P, Tinazzi I, Costa L, McGonagle D, Peluso R, Del Puente A, Addimanda O, Marchetta A, Possemato N, Tasso M, Salvarani C, Scarpa R, Caso F Abstract OBJECTIVE: To use ultrasonography to explore whether the duration of psoriatic dactylitis was associated with different patterns of extracapsular and synovial based involvement. METHODS: One hundred cases of hand dactylitis from 85 psoriatic arthritis (PsA) patients were consecutively enrolled in a multicentre cross-sectional study and divided into two groups according to dactylitis duration (shorter or longer than the median: 20 wee...
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Association of Childhood Abuse with Incident Systemic Lupus Erythematosus in Adulthood in a Longitudinal Cohort of Women.
We examined if childhood abuse was associated with heightened risk of incident systemic lupus erythematosus (SLE). METHODS: Data were from the Nurses' Health Study II, a cohort of U.S. female nurses enrolled in 1989, followed with biennial questionnaires. We measured childhood physical and emotional abuse with the Physical and Emotional Abuse Subscale of the Childhood Trauma Questionnaire and sexual abuse with the Sexual Maltreatment Scale of the Parent-Child Conflict Tactics Scale, both administered in 2001. We identified incident SLE (>4 American College of Rheumatology 1997 classification criteria) through 2015. ...
Source: Journal of Rheumatology - May 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Effect of Concomitant Disease-modifying Antirheumatic Drugs and Methotrexate Administration Route on Biologic Treatment Durability in Rheumatoid Arthritis: OBRI Cohort Results.
CONCLUSION: Concomitant csDMARD use was associated with a significantly lower hazard for bDMARD discontinuation due to AE among patients with RA followed in routine clinical practice in Ontario, Canada. Neither MTX route of administration nor dose were significant predictors of bDMARD durability. PMID: 30988121 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Precision, Reliability and Responsiveness of a Novel Automated Quantification Tool for Cartilage Thickness: Data from the Osteoarthritis Initiative.
Authors: Bowes MA, Guillard GA, Vincent GR, Brett AD, Wolstenholme CBH, Conaghan PG Abstract OBJECTIVE: Accurate automated segmentation of cartilage should provide rapid reliable outcomes for both epidemiological studies and clinical trials. We aimed to assess the precision and responsiveness of cartilage thickness measured with careful manual segmentation or a novel automated technique. METHODS: Agreement of automated segmentation was assessed against two manual segmentation datasets: 379 MR images manually segmented in-house (Training set), and 582 from the OAI with data available at 0, 1, and 2 years (Biomar...
Source: Journal of Rheumatology - April 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Bacteremia in systemic lupus erythematosus patients from RELESSER: risk factors, clinical and microbiological characteristics and outcomes.
CONCLUSION: Bacteremia occurred mostly in active SLE patients and was frequently associated with severe flares and corticosteroid use. Recurrence and mortality were high. Immunosuppressors, comorbidities and disease-related damage were associated with bacteremia. PMID: 30988123 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Reevaluating Serologic Markers of Poor Prognostic Factors in Rheumatoid Arthritis.
Authors: Weinstein A, McEvilly B, Dervieux T Abstract The article by Alemao, et al 1 documented that acceleration of treatment regimens for 3458 biologic-naive patients with rheumatoid arthritis (RA) did not significantly differ based on the presence or absence of poor prognostic factors (PPF). These findings suggest that, for whatever reason, clinicians were unable to translate PPF into a more aggressive therapeutic approach. PMID: 30988124 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Patient preferences for disease modifying anti-rheumatic drug treatment in rheumatoid arthritis: A systematic review.
CONCLUSION: Overall, the results showed that many patients place a high value on treatment benefits over other treatment attributes including serious or minor side effects, cost or route of administration. The variability in patient preferences highlights the need to individualize treatment choices in RA. PMID: 30988125 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Rates of Total Joint Replacement in the United States: Future Projections to 2020-2040 Using the National Inpatient Sample.
CONCLUSION: Significant increases in use of THA and TKA are expected in the United States in the future, if the current trend continues. The increased use is evident across age groups in both females and males. A policy change may be needed to meet increased demand. PMID: 30988126 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Peripheral manifestations in spondyloarthritis and their impact: an ancillary analysis of the ASAS-COMOSPA study.
CONCLUSION: Peripheral manifestations appear in 64% of patients with SpA. Psoriasis and the absence of HLAB27 are associated with the development of peripheral symptoms. The presence of any peripheral symptom at the time of the visit was associated with higher scores in all PROs. PMID: 30988127 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Anti-CCP3.1 and Anti-CCP-IgA Are Associated with Increasing Age in Individuals Without Rheumatoid Arthritis.
CONCLUSION: Increasing age in individuals without RA should be considered in the interpretation of anti-CCP3.1 positivity. PMID: 30988128 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Response to Early-onset Pamidronate Treatment in Chronic Non-Bacterial Osteomyelitis: A Retrospective Single Center Study.
CONCLUSION: Pamidronate might contribute to improvement in clinical and radiological disease activity in extended CNO, especially after one year of treatment. However, children with continuously active disease after two years of pamidronate treatment were seen. PMID: 30988129 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Construction of a frailty index as a novel health measure in systemic lupus erythematosus.
CONCLUSION: The SLICC inception cohort permits feasible construction of an FI for use in patients with SLE. Even in a relatively young cohort of SLE patients, frailty was common. The SLICC-FI may be a useful tool for identifying SLE patients who are most vulnerable to adverse outcomes but validation of this index is required prior to its use. PMID: 30988130 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Low-dose Glucocorticoid Use Does Not Reduce Biologic Use in Early RA, Nor Do Biologics Reduce the Need for Glucocorticoids.
Authors: Bykerk VP PMID: 30936221 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

The Elusive but Painful Subtalar Joint in Rheumatoid Arthritis.
Authors: Kaeley GS, Ranganath VK, Roth J PMID: 30936222 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

The Role of Ultrasound in Psoriatic Arthritis - Do We Need a Score?
Authors: D'Agostino MA, Coates LC PMID: 30936223 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Hydroxychloroquine - How Much Is Too Much?
Authors: Sandhu VK, Weisman MH PMID: 30936224 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Acrodermatitis Continua of Hallopeau with Psoriatic Arthritis.
Authors: Khosravi-Hafshejani T, Zhou Y, Dutz JP PMID: 30936225 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Gynecologic Vasculitis: Positron Emission Tomography-Computed Tomography Contribution in a Rare Localization of Giant Cell Arteritis.
Authors: Besse MC, Collercandy N, Diot E PMID: 30936226 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Dr. Butendieck, et al, reply.
Authors: Butendieck RR, Abril A, Cortese C PMID: 30936227 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Considerations for evaluating and recommending worker productivity outcome measures: An update from the OMERACT Worker Productivity Group.
CONCLUSION: We have advanced our understanding of the performance of presenteeism measures and have developed approaches to describing thresholds of meaning. PMID: 30936275 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Atlanto-axial Pannus in Patients with and without Rheumatoid Arthritis.
Authors: Joyce AA, Williams J, Shi J, Mandell JC, Isaac Z, Ermann J Abstract OBJECTIVE: Pannus formation in the atlanto-axial joint is a well-recognized complication of rheumatoid arthritis (RA). Occasionally, atlanto-axial pannus is reported when patients without a history of RA undergo magnetic resonance imaging (MRI) of the cervical spine. We sought to further characterize these patients. METHODS: The Partners HealthCare Research Patient Data Registry was free-text searched for 'atlanto-axial' AND 'pannus' in cervical spine MRI reports from 2001 to 2015. Cases with MRI reports describing pannus were reviewed...
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Exploring Dimensions of Stiffness in Rheumatoid and Psoriatic Arthritis: The ARAD and OMERACT Stiffness Special Interest Group collaboration.
CONCLUSION: Stiffness ratings were similar between PsA and RA. Different dimensions of stiffness were strongly correlated. Stiffness severity and impact both independently predicted mHAQ. Stiffness was important to participants, however, measuring multiple dimensions of stiffness may have minimal additive value. PMID: 30936277 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Prediction of ankylosing spondylitis in the population-based HUNT study by a genetic risk score combining 110 SNPs of genome-wide significance.
The objectives were to construct a weighted genetic risk score (wGRS) using currently known genome-wide susceptibility SNPs, and evaluate its predictive ability for AS in the Norwegian population-based Nord- Trøndelag Health Study (HUNT). METHODS: AS cases (n=164) and controls (n=49,032) were from the second (1995- 1997) and third (2006-2008) waves of the HUNT study, to which the entire adult population of the northern region of Trøndelag was invited. A wGRS based on 110 SNPs weighted by published odds ratios for AS was constructed, representing each person's carriage of all risk variants. Logistic regres...
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Sleep Quality and Fatigue are Associated with Hip Osteoarthritis Pain Exacerbations: An Internet-Based Case-Crossover Study.
CONCLUSION: Poor sleep quality and greater fatigue were related to pain exacerbation in persons with symptomatic hip OA. Sleep disorders and fatigue should be considered when dealing with pain exacerbations and more research is necessary to refine and further elaborate on this novel finding. PMID: 30936279 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

A Review of Cauda Equina Syndrome in Ankylosing Spondylitis: Challenges in Diagnosis, Management, and Pathogenesis.
CONCLUSION: CES is a rare yet debilitating neurologic complication of longstanding AS. The pathophysiology and treatments are far from clear. We postulate that chronic enthesitis of the vertebral column initiates the process that results in dural stiffening and formation of ectasias causing downstream nerve root damage. PMID: 30936280 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Association between enthesitis and health-related quality of life in psoriatic arthritis in anti-TNF-na ïve patients from two Phase 3 ustekinumab trials.
CONCLUSION: Improvement in enthesitis at week24 was associated with improvements in physical function/HRQoL regardless of ACR20 response. PMID: 30936281 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Perceptions of Pregnancy and Lactation from the Pregnancy and Lactation Autoimmune Network (PLAN) Registry.
CONCLUSION: This study highlights an unmet need in patients with AIRDs of childbearing potential for data and education regarding pregnancy and lactation. PMID: 30936282 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Do Clinical Correlates of Knee Osteoarthritis Predict Outcome to Intra-Articular Steroid Injections?
CONCLUSION: Among patients with symptomatic knee OA, tenderness around the knee was associated with better short-term outcome to IASI. However, clinical-related factors did not predict longer-term response while those with chronic widespread pain and depressive symptoms were less likely to obtain longer-term benefit. PMID: 30936283 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Pain measurement in rheumatic and musculoskeletal diseases: where to go from here? Report from a Special Interest Group at OMERACT 2018.
CONCLUSION: Characterizing and assessing the spectrum of pain experience across RMDs in a standardized fashion is the future objective of the OMERACT pain working group. PMID: 30936284 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Therapy With Biologic Agents After Diagnosis of Solid Malignancies: Results From the Corrona Registry.
CONCLUSION: In real-world practice, nearly one-third of RA patients with a cancer diagnosis were treated with systemic therapy in the immediate visit after malignancy diagnosis and a considerable percentage of malignancy survivors initiated biologic therapy within 3 years. The majority of biologic/tsDMARD initiations post- malignancy diagnosis was a TNFi. PMID: 30936285 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Assessing the Educational Needs of Canadians with Systemic Sclerosis.
Authors: Semalulu T, Beattie KA, Larché MJ Abstract Changes in appearance, significant morbidity, and the absence of disease-modifying therapies may lead to psychosocial issues in patients with systemic sclerosis (SSc)1,2,3,4 Limited education may contribute to poor medication adherence5 Education of patients could potentially mediate some of these outcomes2,6 because patient education in rheumatic disease improves self-efficacy and self-management7,8. PMID: 30936286 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Scleroderma renal crisis (SRC): risk factors for an increasingly rare organ complication.
CONCLUSION: In this cohort, SRC has become a rare complication. By far the highest risk for SRC was associated with the detection of anti-RNAP antibodies and proteinuria. PMID: 30936287 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

The validity of gout diagnosis in primary care, results from a patient survey.
CONCLUSION: The vast majority of gout cases in primary care fulfill classification criteria and are valid for research purposes. PMID: 30936288 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

The development and evaluation of a personalized training in shared decision making skills for rheumatologists.
CONCLUSION: The training was received well by the participating rheumatologists. Even in a population of rheumatologists that communicate well, 62% reported improvement. The training program increased awareness about the principles of SDM in patients and physicians, and improved phycisian's communicative skills, but did not lead to further improvement in patients' satisfaction, which was already high. PMID: 30936289 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Whole-body magnetic resonance imaging inflammation in peripheral joints and entheses in axial spondyloarthritis: Distribution and changes during adalimumab treatment.
Authors: Krabbe S, Eshed I, Sørensen IJ, Jensen B, Møller JM, Balding L, Madsen OR, Pedersen SJ, Østergaard M Abstract OBJECTIVE: To investigate the distribution of whole-body MRI (WBMRI) inflammatory lesions of peripheral joints and entheses, their response to adalimumab treatment and agreement with clinical measures of disease activity in patients with axial spondyloarthritis. METHODS: Explorative analysis of an investigator-initiated randomized controlled trial of adalimumab. WBMRI was performed at weeks 0, 6, 24 and 48. Detailed analyses of WBMRI lesions in peripheral joints and enthese...
Source: Journal of Rheumatology - April 3, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research

Localized Myofascial Inflammation by Magnetic Resonance Imaging in Recent-Onset Polymyalgia Rheumatica and Effect of Tocilizumab Therapy.
CONCLUSION: Localized myofascial inflammatory lesions are common in recent-onset PMR and improve during tocilizumab therapy. PMID: 30877202 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 17, 2019 Category: Rheumatology Tags: J Rheumatol Source Type: research