Team-rehabilitation in inflammatory arthritis benefits functional outcomes along with improved body composition which is associated with improved cardiorespiratory fitness.
CONCLUSION: In patients with inflammatory arthritis, 4-week team-rehabilitation benefited body composition, level of physical functioning, activity and CRF for up to 12 months. Measures of physical function and activity were linked to HAQ over time, whereas body composition was linked to CRF. PMID: 33526616 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - February 3, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Covid-19 in Children with Rheumatic Diseases in the Spanish National Cohort EPICO-AEP.
Authors: Calvo C, Udaondo C, Rheumatic Diseases EPICO-AEP Working Group Abstract SARS-CoV-2 infection in children is relatively mild. Approximately 10% of identified cases are pediatric[1], with a small proportion needing hospitalization. About 25-60% of children admitted with COVID-19 have comorbidities[2,3]. PMID: 33526617 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - February 3, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Safety and Efficacy of Filgotinib: Up to 4-Year Results From an Open-Label Extension Study of Phase 2 Rheumatoid Arthritis Programs.
CONCLUSION: Filgotinib was well tolerated with a 4-year safety profile comparable to that of the parent trials, both in patients receiving combination therapy with MTX or as monotherapy. PMID: 33526618 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - February 3, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Joint association of moderate-to-vigorous intensity physical activity and sedentary behavior with incident functional limitation: data from the Osteoarthritis Initiative (OAI).
Authors: Master H, Thoma LM, Dunlop DD, Christiansen MB, Voinier D, White DK Abstract OBJECTIVE: To examine joint association of moderate-to-vigorous intensity physical activity (MVPA) and sedentary behavior with the risk of developing functional limitation 4 years later in adults with knee OA. METHODS: Using 48-month (baseline) accelerometry data from Osteoarthritis Initiative, , we classified participants as Active-Low Sedentary (≥1 10-minute bout/week of MVPA, lowest tertile for standardized sedentary time), Active-High Sedentary (≥1 10-minute bout/week of MVPA, top two tertiles for standardized sedent...
Source: Journal of Rheumatology - February 3, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Clinical Bedside Tools to Assess Systemic Sclerosis Vasculopathy: Can digital thermal monitoring and sublingual microscopy identify patients with digital ulcers?
Authors: Frech TM, Ou Z, Presson AP Abstract OBJECTIVE: Sublingual microscopy assesses systemic sclerosis (SSc) vasculopathy. Digital thermal monitoring (DTM) may identify patients at risk for digital ulcer (DU). The purpose of this analysis was to assess sublingual microscopy and DTM in SSc patients with and with no previous DU in order to determine the utility of these clinical tools. METHODS: SSc registry patients with clinical data had both DTM and sublingual microscopy on the same day were included in this cross-sectional analysis. DTM quantifies vascular reactivity index (VRI). Sublingual microscopy measu...
Source: Journal of Rheumatology - February 3, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Differences in Health Care Transition Views, Practices, and Barriers Amongst North American Pediatric Rheumatology Clinicians from 2010 to 2018.
In this study we aimed to compare current transition practices and beliefs among Childhood Arthritis and Rheumatology Research Alliance (CARRA) rheumatology providers with transition practices from a 2010 provider survey published by Chira et al. METHODS: In 2018, CARRA members completed a 25-item online survey about healthcare transition. Got Transition's™ Current Assessment of Health Care Transition Activities was used to measure clinical transition processes on a scale of 1 (basic) to 4 (comprehensive). Bivariate analyses were used to compare 2010 and 2018 survey findings. RESULTS: Over half of CARRA members c...
Source: Journal of Rheumatology - February 3, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

ANCA-Associated Vasculitis Management in the United States: Data from the Rheumatology Informatics System for Effectiveness (RISE) Registry.
CONCLUSION: This is the first study to evaluate the demographics and management of AAV by rheumatologists outside of major referral centers. Management strategies vary widely but cyclophosphamide is rarely used. These observations can be used to inform future research priorities. Additional studies are needed to characterize AAV severity in RISE and patient and provider treatment preferences. PMID: 33526622 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - February 3, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Current smoking negatively affects the response to methotrexate in RA in a dose-responsive way, independently of concomitant prednisone use.
Authors: Safy-Khan M, de Hair MJH, Welsing PMJ, van Laar JM, Jacobs JWG, Society for Rheumatology research Utrecht (SRU) Abstract OBJECTIVE: Current smoking reduces clinical response to several disease-modifying antirheumatic drugs (DMARDs). It is unknown if this is also the case for prednisone. We aimed to determine whether current smoking affects the clinical response to concomitant prednisone in a methotrexate (MTX)-based treatment strategy. METHODS: In the CAMERA-II trial, early rheumatoid arthritis (RA) patients initiated an MTX-based strategy and were randomized to concomitant prednisone (MTX+pred) or pla...
Source: Journal of Rheumatology - February 3, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Remission in Gout: The Key to Patient Satisfaction?
Authors: Toprover M, Pillinger MH PMID: 33526647 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - February 3, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

A Synovial Cyst of the Temporomandibular Joint.
Authors: Chatelet F, Benichou L, Ketoff S PMID: 33526648 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - February 3, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Black-blood Magnetic Resonance Imaging in Giant Cell Arteritis.
Authors: Vynckier J, Demeestere J, Lambert J PMID: 33526649 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - February 3, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

UCLA Scleroderma Clinical Trials Consortium Gastrointestinal Tract 2.0 Reflux Scale correlates with impaired Esophageal Scintigraphy findings in Systemic Sclerosis.
Authors: Abignano G, Mennillo GA, Lettieri G, Temiz Karadag D, Carriero A, Padula AA, Del Galdo F, Khanna D, D'Angelo S Abstract OBJECTIVE: The University of California Los Angeles Scleroderma Clinical Trials Consortium gastrointestinal tract 2.0 (UCLA GIT 2.0) questionnaire is a self-reported tool measuring gastrointestinal (GI) quality of life in systemic sclerosis (SSc) patients. Scarce data are available on the correlation between patient reported GI symptoms and motility dysfunction as assessed by esophageal transit scintigraphy. METHODS: We evaluated the UCLA GIT 2.0 reflux scale in SSc patients admitted ...
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Increased Risk of Valvular Heart Disease in Systemic Sclerosis: An Underrecognized Cardiac Complication.
CONCLUSION: SSc patients have a 4-fold increase in the prevalence of moderate/severe VHD at diagnosis compared to non-SSc patients. They also have a 4-fold increased risk of developing moderate/severe VHD after diagnosis of SSc. Aortic stenosis and mitral regurgitation have a much higher prevalence in SSc patients, besides secondary tricuspid regurgitation. Underlying mechanisms for this association require further elucidation. PMID: 33452164 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Association of patients' familiarity and perceptions of efficacy and risks with the use of opioid medications in the management of osteoarthritis.
CONCLUSION: Among adults with knee/hip OA, opioid use was associated with believing that the medication was beneficial and low risk and being familiar with the treatment. PMID: 33452165 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Erectile Dysfunction and Cardiovascular Risk in Men with Rheumatoid Arthritis: A Population- Based Cohort Study.
CONCLUSION: Incidence of ED was not statistically increased in RA. Although patients with both RA and ED had a similar overall cardiovascular risk to those with RA alone, men with both RA and ED had decreased risk of heart failure, myocardial infarction and death, as well as an increased risk of peripheral arterial disease. Further studies are needed to clarify these associations and their implications for pathogenesis and therapeutics. PMID: 33452166 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Assessment of widespread and extra-articular pain in psoriatic arthritis: a case-control study.
CONCLUSION: The main results showed that widespread and extra-articular pain was present in PsA patients, showing that this non-articular pain had an impact on important disease domains. The present study could contribute to an important aspect of this challenging and multifaceted disease, such as the assessment of widespread pain. PMID: 33452167 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Relation of NSAID, DMARD and TNF-inhibitors for Ankylosing Spondylitis and Psoriatic Arthritis to Risk of Total Hip and Knee Arthroplasty.
CONCLUSION: Odds of THA/TKA were not reduced with any combinations of NSAIDs, DMARDs, or TNFi among persons with AS or PsA. Given current utilization patterns in this population of US adults with AS and PSA, these medical therapies did not appear to be associated with less end stage peripheral joint damage. PMID: 33452168 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Hyperviscosity Syndrome in Rheumatoid Arthritis.
Authors: Miller JB, Baer AN Abstract Hyperviscosity syndrome (HVS) is a life-threatening condition often occurring as a complication of Waldenström macroglobulinemia (WM) but rarely in the context of rheumatic disease. Given its rarity, diagnosis can be delayed, leading to greater morbidity. PMID: 33452169 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Dr. Kiltz, et al reply.
Authors: Kiltz U, Wendling D, Braun J Abstract We thank Dr. Queiro and colleagues for their interest in our editorial review and the fascinating field of axial spondyloarthritis (axSpA)1 Queiro and colleagues point out that disease-specific assessments used in routine care for patients with axSpA focus on assessment of disease activity and physical function but do not look much at the considerable variety of symptoms related to axSpA. PMID: 33452170 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Use of Hydroxychloroquine And Risk of Heart Failure in Patients With Rheumatoid Arthritis.
CONCLUSION: Use of HCQ was not associated with development of HF in patients with RA in this study. Further studies are needed to understand the impact of higher doses of HCQ on development of HF in RA. PMID: 33452171 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Essential hypertension worsens left ventricular contractility in systemic sclerosis.
Authors: Mercurio V, Hinze AM, Hummers LK, Wigley FM, Shah AA, Mukherjee M Abstract OBJECTIVE: Primary cardiac involvement in systemic sclerosis (SSc) is prevalent and morbid, however the influence of traditional cardiovascular risk factors such as essential hypertension (HTN) are unclear. In the present study, we sought to understand the effects of HTN on left ventricular (LV) contractility in SSc patients using echocardiographic speckle-derived global longitudinal strain (GLS). METHODS: 56 SSc patients with HTN (SSc+HTN+) and 82 SSc patients without HTN (SSc+ HTN-) were compared with 40 non-SSc controls with ...
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Absence of Association Between Abatacept Exposure and Initial Infection in Patients With Juvenile Idiopathic Arthritis.
CONCLUSION: In patients aged 2-17 years with pJIA, no evidence of association between higher levels of exposure to intravenous or subcutaneous abatacept and incidence of infection was observed. PMID: 33452173 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Prevalence of non-radiographic sacroiliitis in patients with psoriatic arthritis: a real-life observational study.
CONCLUSION: The prevalence of active sacroiliitis among a real-life population of patients with PsA was 26%. However, the prevalence of non-radiographic sacroiliitis was low (11%) compared to radiographic sacroiliitis (28.7%) seen in patients with longer disease duration. IBP was not a sensitive indicator for the presence of early stage sacroiliitis that was commonly asymptomatic. PMID: 33452174 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Development of a Patient-centered Quality Measurement Framework for Measuring, Monitoring, and Optimizing Rheumatoid Arthritis Care in Canada.
CONCLUSION: The proposed framework builds upon existing measures capturing early access to care and treatment in RA and adds important PMs to promote high-quality RA care and outcome measurement. In the next phase, the authors will test the framework in clinical practice in addition to addressing certain areas where no suitable PMs were identified. PMID: 33452175 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

ASAS Health Index as an Addition to Routine Clinical Practice.
Authors: Queiro R, Alonso-Castro S, Alperi M Abstract We have read with great interest the recent editorial published in The Journal by Dr. Kiltz, et al, referring to the possibility of using the Spondyloarthritis international Society Health Index (ASAS HI) as an all-in-one in the assessment of axial spondyloarthritis (axSpA)1 AxSpA has been evaluated over the years with different tools that have tried to determine the degree of activity [Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)/Ankylosing Spondylitis Disease Activity Score (ASDAS)], functional limitations (Bath Ankylosing Spondylitis Functional...
Source: Journal of Rheumatology - January 17, 2021 Category: Rheumatology Tags: J Rheumatol Source Type: research

Identifying axial spondyloarthritis patients in large datasets: Expanding possibilities for observational research.
CONCLUSION: The axSpA identification methods demonstrated a range of performance attributes in the general VA population that may be appropriate for various types of studies. The novel identification algorithms may expand the scope of research, by enabling identification of more diverse axSpA populations. PMID: 33259327 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - December 2, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Antiphospholipid Antibody Profile Stability Over Time: Prospective Results from APS ACTION Clinical Database and Repository.
CONCLUSION: Approximately 80% of our international cohort patients with clinically meaningful aPL profile at baseline maintain such at a median follow-up of five years; triple aPL-positivity increase the odds of a stable aPL profile. These results will guide future validation studies of stored blood samples through APS ACTION Core Laboratories. PMID: 33259328 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - December 2, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Does the 1-year Decline in Walking Speed Predict Mortality Risk Beyond Current Walking Speed in Adults With Knee Osteoarthritis?
Authors: Master H, Neogi T, LaValley M, Thoma LM, Zhang Y, Voinier D, Christiansen MB, White DK Abstract OBJECTIVE: To investigate whether walking speed at 1 timepoint, decline over the past 12 months, or both predict mortality risk over 11 years in adults with, or at risk of, knee osteoarthritis (OA). METHODS: Using the data from the Osteoarthritis Initiative, we defined slow versus adequate walking speed as walking
Source: Journal of Rheumatology - December 2, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Imaging pattern and outcome of stroke in patients with systemic lupus erythematosus: a case-control study.
Authors: Tsoi LK, Mok CC, Man BL, Fu YP Abstract OBJECTIVE: To evaluate the outcome of stroke in patients with systemic lupus erythematosus (SLE). METHODS: Patients who fulfilled ≥4 ACR criteria for SLE and had a history of stroke from 1997-2017 were identified. The functional outcome of stroke (assessed by the modified Rankin Scale) at 90 days, mortality, stroke complications and recurrence were retrospectively studied and compared with matched non-SLE patients with stroke. RESULTS: 40 SLE patients and 120 non-SLE patients with stroke (age at stroke 44.6±13.8 years; 88% women) were studied. Ische...
Source: Journal of Rheumatology - December 2, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Factors Associated with Rapid Progression to End Stage Kidney Disease in Lupus Nephritis.
CONCLUSION: Catastrophic progression to ESKD is uncommon in LN. The major associated factors are poor compliance and distinct histopathologic features such as thrombotic microangiopathy, collapsing glomerulopathy and concomitant anti-GBM nephropathy. PMID: 33259331 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - December 2, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Racial differences in patient-provider communication, patient self-efficacy, and their associations with lupus-related damage: a cross-sectional survey.
CONCLUSION: African-Americans had more severe SLE and perceived more hurried communication with providers. Both worse communication and lower self-efficacy were associated with having SLE-related damage among African-Americans but not Caucasians, suggesting that these factors should be investigated as potential interventions to reduce SLE racial disparities. PMID: 33259332 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - December 2, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

ASAS Health Index: The "All in One" for Spondyloarthritis Evaluation?
ASAS Health Index: The "All in One" for Spondyloarthritis Evaluation? J Rheumatol. 2020 Oct 01;47(10):1457-1460 Authors: Kiltz U, Wendling D, Braun J PMID: 33004479 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

The Storm Beneath the Storm: MAS-HLH in Inflammatory Myopathies.
Authors: Schulert GS PMID: 33004480 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Iliopsoas Muscle Involvement due to Granulomatosis with Polyangiitis.
Authors: Taniguchi Y, Nishikawa H PMID: 33004481 [PubMed - in process] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Correction.
Authors: PMID: 33004482 [PubMed] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Correction.
Authors: PMID: 33004483 [PubMed] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Clinical phenotyping of primary Sj ögren's patients using salivary gland ultrasonography - data from the RESULT cohort.
CONCLUSION: SGUS positive patients show a distinct clinical phenotype compared with SGUS negative patients in all aspects of the disease: clinical, functional, serological and PROMs. SGUS could be a helpful tool in selecting patients for clinical trials and estimating treatment need. PMID: 33004530 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Time-trends in Opioid Use Disorder Hospitalizations in Gout, Rheumatoid arthritis, Fibromyalgia, Osteoarthritis, and Low Back Pain.
CONCLUSION: OUD-hospitalizations increased in all 5 musculoskeletal diseases studied, but the rate of increase differed. Awareness of these OUD-hospitalization trends in 5 musculoskeletal diseases among providers, policy-makers and patients is important. Development and implementation of interventions, policies and practices to potentially reduce OUD-associated impact in people with rheumatic diseases is needed. PMID: 33004531 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Impact of Multidomain Disease Presentations on Patients With Psoriatic Arthritis in the Corrona Psoriatic Arthritis/Spondyloarthritis Registry.
CONCLUSION: In this US real-world cohort, most patients had multidomain disease presentations, which was associated with worse disease activity, QOL, and work productivity measures. This study highlights the heterogeneity of PsA and the importance of assessing all PsA domains for optimizing disease management. PMID: 33004532 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Infertility Causes and Pregnancy Outcome in Patients With Familial Mediterranean Fever (FMF) and Controls.
CONCLUSION: Colchicine medication and controlled FMF disease do not adversely affect the reproductive system and pregnancy outcome. However, a lack of an appropriate colchicine treatment may cause infertility and poor pregnancy outcome. PMID: 33004533 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Tofacitinib Persistence in Patients with Rheumatoid Arthritis: A Retrospective Cohort Study.
CONCLUSION: Further research is warranted to understand the reasons for discontinuation of tofacitinib despite its ease of administration and to understand the observed differences between switchers and new users. PMID: 33004534 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Variability in Urate-lowering Therapy Prescribing: A Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN) Physician Survey.
Authors: Stamp LK, Taylor W, Gaffo A Abstract Gout is common in people with chronic kidney disease (CKD) and its treatment is frequently suboptimal in this special population due to concerns over adverse events and/or efficacy of medications. There is controversy about the use of urate-lowering therapy (ULT) in those with CKD and lack of agreement about the dosing of allopurinol, the recommended first-line ULT1,2. PMID: 33004535 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

STRATUS, a Phase II Study of Abituzumab in Patients with Systemic Sclerosis-associated Interstitial Lung Disease.
CONCLUSION: Further investigation of abituzumab for treatment of SSc-ILD is required. PMID: 33004536 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Effect of stem cell injections on osteoarthritis-related structural outcomes - a systematic review.
CONCLUSION: This systematic review of early phase clinical trials showed consistent evidence for a beneficial effect of intra-articular MSC injections on articular cartilage and subchondral bone. Due to the heterogeneity of MSCs, modest sample sizes, methodological limitations, and potential for publication bias, further work is needed before this therapy is recommended in the management of osteoarthritis. PMID: 33004537 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Urinary N-telopeptide as a Biomarker of Disease Activity in Patients with Chronic Nonbacterial Osteomyelitis Who Have Not Received Bisphosphonates.
Authors: Perkins A, Stevens A, Ferguson PM, Zhao Y Abstract Chronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory disease that causes bone destruction, soft tissue swelling, and bone pain1 Diagnosis and treatment are hindered by a lack of a reliable laboratory test to assess disease activity. Bone inflammation in CNO is associated with increased osteoclastic activity and bone resorption, causing focal accelerated breakdown of bone collagen. PMID: 33004538 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Long Term Follow-up and Optimization of Infliximab in Refractory Uveitis Due to Beh çet's Disease. National Study of 103 Caucasian Patients.
CONCLUSION: IFX seems to be effective and relatively safe in Caucasian patients with refractory BD uveitis. IFX optimization is effective, safe, and cost-effective. PMID: 33004539 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - October 3, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Evaluating quality of care for rheumatoid arthritis for the population of Alberta using system-level performance measures.
CONCLUSION: The existing Alberta health care system for RA is suboptimal, indicating barriers to accessing specialty care and treatment. The results inform quality improvement initiatives required within the province to meet national standards of care. PMID: 32934120 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - September 17, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

Reliability and Change in Erosion Measurements by High-Resolution peripheral Quantitative Computed Tomography in a Longitudinal Dataset of Rheumatoid Arthritis Patients.
CONCLUSION: This exercise confirmed good reliability of HR-pQCT erosion measurements and their ability to detect change over time. PMID: 32934121 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - September 17, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

The Serological Status Affects the Prognostic Role of Salivary Gland Histology in Primary Sj ögren Syndrome.
The Serological Status Affects the Prognostic Role of Salivary Gland Histology in Primary Sjögren Syndrome. J Rheumatol. 2020 Sep 15;: Authors: Carubbi F, Alunno A Abstract We read with interest the article by Sharma, et al that evaluated a cohort of patients with symptoms of mucosal dryness undergoing diagnostic workup for the suspicion of primary Sjögren syndrome (pSS)1 The assessment also included a minor salivary gland (MSG) biopsy and patients were classified as pSS if fulfilling the histological [focus score (FS) ≥ 1], serological (anti-Ro based on the American College of Rheumatolog...
Source: Journal of Rheumatology - September 17, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research

CanVasc consensus recommendations for the management of antineutrophil cytoplasm antibody-associated vasculitis: 2020 update.
CONCLUSION: The 2020 updated recommendations provide rheumatologists, nephrologists, and other specialists caring for patients with AAV in Canada with new management guidance, based on current evidence and consensus from Canadian experts. PMID: 32934123 [PubMed - as supplied by publisher] (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - September 17, 2020 Category: Rheumatology Tags: J Rheumatol Source Type: research