An Uncommon Presentation of Secondary Syphilis
J Rheumatol. 2024 Mar 15:jrheum.2024-0119. doi: 10.3899/jrheum.2024-0119. Online ahead of print.ABSTRACTSyphilis is a chronic venereal disease caused by Treponema pallidum (TP). Destructive arthritis is rare in its primary and secondary stages but can occur in the tertiary stage and its congenital form.PMID:38490675 | DOI:10.3899/jrheum.2024-0119 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Rafaela Nicolau Daniela Oliveira Jo ão Pacheco Pedro Madureira Source Type: research
What is allopurinol "failure" and what should we do about it?
J Rheumatol. 2024 Mar 15:jrheum.2024-0144. doi: 10.3899/jrheum.2024-0144. Online ahead of print.ABSTRACTAllopurinol is the most widely used urate-lowering medication world-wide. However, allopurinol "failure" is frequently observed in clinical practice. In this review, we provide a framework for assessing allopurinol "failure", which includes failure of allopurinol to control serum urate concentrations, failure of allopurinol to control clinical symptoms, and failure of allopurinol due to an adverse drug reaction. Understanding the causes of allopurinol "failure" underpins the approach required to turn "failure" into "succ...
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Lisa K Stamp Nicola Dalbeth Source Type: research
VEXAS Syndrome: Clinical Case Series From a Canadian Cohort
J Rheumatol. 2024 Mar 15:jrheum.2022-0226. doi: 10.3899/jrheum.2022-0226. Online ahead of print.ABSTRACTVEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic; OMIM #301054) syndrome is an autoinflammatory condition first described in November 2020.1 It is characterized by vacuoles in myeloid and erythroid precursor cells on bone marrow biopsy and caused by a monogenic somatic mutation in the ubiquitin-like modifier activating enzyme 1 (UBA1) gene.1,2.PMID:38490666 | DOI:10.3899/jrheum.2022-0226 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Stephen Williams Mohan Stewart Aurore Fifi-Mah Natasha Dehghan Source Type: research
An environmental scan and appraisal of patient online resources for managing rheumatoid arthritis flares
CONCLUSION: There is high variability in the actionability and understandability of RA flare materials online and only 23% of resources were highly recommended by researchers and patient partners.PMID:38490667 | DOI:10.3899/jrheum.2023-1025 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Shakeel Subdar Alison M Hoens Krista White Nicole M S Hartfeld Kiran Dhiman Keeva Duffey Claire E Heath Gisele Lamoureux Christine Graveline Eileen Davidson Glen Hazlewood Diane Lacaille Elena Lopatina Megan R W Barber Karen L Then Trafford Crump Saania Z Source Type: research
Comparison Of Attainment And Protective Effects Of Lupus Low Disease Activity State In Patients With Newly Diagnosed Versus Established SLE
CONCLUSION: LLDAS attainment is protective from flare in recent onset SLE. Significant protection from damage accrual was not observed, due to low rates of damage accrual in the first years after SLE diagnosis.PMID:38490668 | DOI:10.3899/jrheum.2023-0900 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Vera Golder Rangi Kandane-Rathnayake Worawit Louthrenoo Yi-Hsing Chen Jiacai Cho Aisha Lateef Laniyati Hamijoyo Shue-Fen Luo Yeong-Jian J Wu Sandra V Navarra Leonid Zamora Zhanguo Li Sargunan Sockalingam Yasuhiro Katsumata Masayoshi Harigai Yanjie Hao Zhu Source Type: research
Balancing Honesty and Hope: The Art of Truth-Telling in Medicine
J Rheumatol. 2024 Mar 15:jrheum.2024-0162. doi: 10.3899/jrheum.2024-0162. Online ahead of print.ABSTRACT"Is there any hope I can walk again?"I looked up to see an elderly man lying in the hospital bed struggling to put on his portable hearing aid. I gently removed his blanket to help untangle the wires, exposing his frail body in the process.PMID:38490669 | DOI:10.3899/jrheum.2024-0162 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Leonard Kuan-Pei Wang Source Type: research
Cranial Giant Cell Arteritis and Subdural Hematoma
J Rheumatol. 2024 Mar 15:jrheum.2024-0008. doi: 10.3899/jrheum.2024-0008. Online ahead of print.ABSTRACTAlthough it is extremely rare, a few cases of giant cell arteritis (GCA) associated with chronic subdural hematoma (SDH) have been reported.1,2A 68-year-old woman, who had no history of provoking falls, seizures, alcoholism, or coagulopathy, presented with recent onset pulsatile headache, fever, and mild dizziness.PMID:38490670 | DOI:10.3899/jrheum.2024-0008 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Hirotaka Yamamoto Yoshinori Taniguchi Source Type: research
The Banks of the Indus
J Rheumatol. 2024 Mar 15:jrheum.2024-0138. doi: 10.3899/jrheum.2024-0138. Online ahead of print.ABSTRACTI remember the banks of the IndusThe silt and the paternal loveCarefree runs, clear minds under the basking sunIt feels to be the time when I truly livedAway from the realities, far from the worldly touchA place all to me where I thrived.PMID:38490671 | DOI:10.3899/jrheum.2024-0138 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Ripudaman Singh Source Type: research
A Rare Diagnosis of Infiltrative Muscle Disease in a Patient With Multiple Joint Pain and Fever
J Rheumatol. 2024 Mar 15:jrheum.2023-0882. doi: 10.3899/jrheum.2023-0882. Online ahead of print.ABSTRACTHemophagocytic lymphohistiocytosis (HLH) is characterized by excessive immune activation.1 It involves the activation of lymphocytes and histiocytes that infiltrate various organs and release cytokines.1.PMID:38490672 | DOI:10.3899/jrheum.2023-0882 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Chang Guk Kim Yeo Ju Kim Seungsam Paik Sang-Cheol Bae Source Type: research
Defining the minimal important change and meaningful change value of the disease activity index for psoriatic arthritis: a Chinese longitudinal study
CONCLUSION: MIC, offering physicians an additional means to contextualize the patient's perception of disease activity during treatment, and a change of 10.5 is likely to be regarded as a clinically meaningful change, enhancing the utility of DAPSA in PsA clinical trials.PMID:38490673 | DOI:10.3899/jrheum.2023-1085 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Yijie Liu Minjia Tan Kun Hu SiChun Deng Lu Jian Junchen Chen Mi Zhang Yehong Kuang Source Type: research
Maximal exercise tolerance, objective trunk strength and mobility measurements in axial spondyloarthritis
CONCLUSION: Strength is more affected than mobility when compared to healthy controls. Likewise, mainly the metabolic component of aerobic capacity is impaired, affecting cardiopulmonary fitness. These findings indicate that future personalized exercise programs in axSpA patients should incorporate exercises for cardiopulmonary fitness next to strength and mobility training.PMID:38490674 | DOI:10.3899/jrheum.2023-1046 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Sophie De Mits Tine Willems Patrick Calders Lieven Danneels Ga ëlle Varkas Filip Van den Bosch Dirk Elewaut Philippe Carron Source Type: research
An Uncommon Presentation of Secondary Syphilis
J Rheumatol. 2024 Mar 15:jrheum.2024-0119. doi: 10.3899/jrheum.2024-0119. Online ahead of print.ABSTRACTSyphilis is a chronic venereal disease caused by Treponema pallidum (TP). Destructive arthritis is rare in its primary and secondary stages but can occur in the tertiary stage and its congenital form.PMID:38490675 | DOI:10.3899/jrheum.2024-0119 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Rafaela Nicolau Daniela Oliveira Jo ão Pacheco Pedro Madureira Source Type: research
What is allopurinol "failure" and what should we do about it?
J Rheumatol. 2024 Mar 15:jrheum.2024-0144. doi: 10.3899/jrheum.2024-0144. Online ahead of print.ABSTRACTAllopurinol is the most widely used urate-lowering medication world-wide. However, allopurinol "failure" is frequently observed in clinical practice. In this review, we provide a framework for assessing allopurinol "failure", which includes failure of allopurinol to control serum urate concentrations, failure of allopurinol to control clinical symptoms, and failure of allopurinol due to an adverse drug reaction. Understanding the causes of allopurinol "failure" underpins the approach required to turn "failure" into "succ...
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Lisa K Stamp Nicola Dalbeth Source Type: research
VEXAS Syndrome: Clinical Case Series From a Canadian Cohort
J Rheumatol. 2024 Mar 15:jrheum.2022-0226. doi: 10.3899/jrheum.2022-0226. Online ahead of print.ABSTRACTVEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic; OMIM #301054) syndrome is an autoinflammatory condition first described in November 2020.1 It is characterized by vacuoles in myeloid and erythroid precursor cells on bone marrow biopsy and caused by a monogenic somatic mutation in the ubiquitin-like modifier activating enzyme 1 (UBA1) gene.1,2.PMID:38490666 | DOI:10.3899/jrheum.2022-0226 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Stephen Williams Mohan Stewart Aurore Fifi-Mah Natasha Dehghan Source Type: research
An environmental scan and appraisal of patient online resources for managing rheumatoid arthritis flares
CONCLUSION: There is high variability in the actionability and understandability of RA flare materials online and only 23% of resources were highly recommended by researchers and patient partners.PMID:38490667 | DOI:10.3899/jrheum.2023-1025 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - March 15, 2024 Category: Rheumatology Authors: Shakeel Subdar Alison M Hoens Krista White Nicole M S Hartfeld Kiran Dhiman Keeva Duffey Claire E Heath Gisele Lamoureux Christine Graveline Eileen Davidson Glen Hazlewood Diane Lacaille Elena Lopatina Megan R W Barber Karen L Then Trafford Crump Saania Z Source Type: research
