Relationship between remnant cholesterol and short ‐term prognosis in acute ischemic stroke patients
ConclusionsIncluding RC as a contributing element may refine the prediction of poor 90-day prognosis for AIS patients. Integrating RC with traditional risk factors can potentially enhance the predictive value for cerebrovascular disease. (Source: Brain and Behavior)
Source: Brain and Behavior - May 8, 2024 Category: Neurology Authors: Zheng Tan,
Qianyun Zhang,
Qiuwan Liu,
Xiaoyin Meng,
Wenpei Wu,
Long Wang,
Juncang Wu Tags: ORIGINAL ARTICLE Source Type: research
Arterial stroke in a child with Seckel syndrome with a pattern of non ‐moyamoya vasculopathy
We describe a child with Seckel syndrome who developed a stroke due to non-moyamoya vasculopathy. (Source: Clinical Case Reports)
Source: Clinical Case Reports - May 8, 2024 Category: General Medicine Authors: Samin Alavi,
Mitra Khalili,
Paniz Mirmoghaddam,
Sharareh Kamfar,
Negar Shams Tags: CASE REPORT Source Type: research
The strength of the patellar and Achilles tendon reflexes is not affected in uncomplicated pregnancy
ConclusionsThe patellar and Achilles reflex strengths are not affected in uncomplicated pregnancy. There is good concordance between neurologists ´ estimations of tendon reflex strengths rated on the NINDS and Mayo scales. (Source: Acta Obstetricia et Gynecologica Scandinavica)
Source: Acta Obstetricia et Gynecologica Scandinavica - May 8, 2024 Category: OBGYN Authors: Isold Nordfjord,
Thora Steingrimsdottir,
Andrea Valtorta,
Agust Hilmarsson,
Haukur Hjaltason Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
The Association of High Lipoprotein(a) Concentration and Risk of Ischaemic Stroke in Atrial Fibrillation Patients
(Source: International Journal of General Medicine)
Source: International Journal of General Medicine - May 8, 2024 Category: General Medicine Tags: International Journal of General Medicine Source Type: research
The Sirtuin 5 Inhibitor MC3482 Ameliorates Microglia ‑induced Neuroinflammation Following Ischaemic Stroke by Upregulating the Succinylation Level of Annexin-A1
AbstractIn our previous study, we concluded that sirtuin 5 (SIRT5) was highly expressed in microglia following ischaemic stroke, which induced excessive neuroinflammation and neuronal injury. Therefore, SIRT5-targeting interventions should reduce neuroinflammation and protect against ischaemic brain injury. Here, we showed that treatment with a specific SIRT5 inhibitor, MC3482, alleviated microglia-induced neuroinflammation and improved long-term neurological function in a mouse model of stroke. The mice were administrated with either vehicle or 2 mg/kg MC3482 daily for 7 days via lateral ventricular injection following...
Source: Journal of NeuroImmune Pharmacology - May 8, 2024 Category: Drugs & Pharmacology Source Type: research
Shifts in Clinical Characteristics, Treatment, and Outcome for Rheumatic Mitral Stenosis: Insights From a 20-Year Multicentre Registry Study in Korea
CONCLUSION: This study observed an increase in patient age, comorbidities, and valve disease severity as the country transitioned from a developing to developed status. Despite a rise in mitral valve interventions, clinical outcomes deteriorated over 20 years, highlighting the need for modified treatment approaches to improve patient outcomes.PMID:38711317 | DOI:10.3346/jkms.2024.39.e152 (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 7, 2024 Category: General Medicine Authors: Hee Jeong Lee Iksung Cho Dae-Young Kim Jang-Won Son Kang-Un Choi Seonhwa Lee In-Cheol Kim Kyu-Yong Ko Kyung Eun Ha Seo-Yeon Gwak Kyu Kim Jiwon Seo Hojeong Kim Chi Young Shim Jong-Won Ha Hyungseop Kim Geu-Ru Hong Jagat Narula Source Type: research
Risk Factors for Complications in Patients Undergoing Temporal Bone Resection and Neck Dissection: Insights From a National Database
CONCLUSIONS: The vast majority of patients undergoing LTBR with ND have no complications and are discharged within a week. Liver disease is a risk factor for medical complications and increased charges. Patients with dementia or a prior stroke are at risk for DNHF, and those with prior anemia are at risk for a wound complication.LAY SUMMARY: This study identified factors related to worse post-operative outcomes in patients undergoing temporal bone resection and neck dissection. Although safe for most patients, an existing diagnosis of liver disease, stroke, dementia, and anemia specifically are at risk for developing negat...
Source: The Annals of Otology, Rhinology, and Laryngology - May 7, 2024 Category: ENT & OMF Authors: Liam M Ordoyne Ivan Alvarez Grant Borne Isabella Fabian Dauren Adilbay Rema A Kandula Ameya A Asarkar Cherie-Ann O Nathan Lindsay Olinde John Pang Source Type: research
Retinal venous occlusion and its association with atherosclerotic vascular disease
Med Clin (Barc). 2024 May 6:S0025-7753(24)00196-9. doi: 10.1016/j.medcli.2024.01.048. Online ahead of print.ABSTRACTRetinal venous occlusion (RVO) is the second most frequent cause of decreased visual acuity due to retinal vascular, after diabetic retinopathy. Its etiology is not completely clear. Current scientific evidence suggests that it is related to the atherosclerotic process given the high number of cardiovascular risk factors and the higher incidence of cardiovascular events in these patients. In fact, RVO implies a 45% higher risk of stroke, 26% of acute myocardial infarction and peripheral vascular disease, 53% ...
Source: Medicina Clinica - May 7, 2024 Category: General Medicine Authors: Mar ía Larrousse Morellón Y éssica López Loureiro Susana Ruiz Bilbao Source Type: research
Association between walking pace and risks of major chronic diseases in individuals with hypertension based on a prospective study in UK biobank: Involvement of inflammation
CONCLUSIONS: Brisk walking pace was linked to reduced risks of major chronic diseases in individuals with hypertension, partially mediated by low-grade inflammation. Improving walking pace may be beneficial for health in individuals with hypertension.PMID:38714275 | DOI:10.1016/j.ypmed.2024.107986 (Source: Cancer Control)
Source: Cancer Control - May 7, 2024 Category: Cancer & Oncology Authors: Yu Peng Fubin Liu Peng Wang Xixuan Wang Changyu Si Jianxiao Gong Huijun Zhou Ming Zhang Fangfang Song Source Type: research
Relationship between the intravascular enhancement sign on three-dimensional T1-weighted turbo spin echo and intraluminal thrombus in middle cerebral artery atherosclerosis
CONCLUSION: The number of IVES vessels and SIR are independent risk factors for ILT. They may provide new monitoring targets for stroke prevention in patients with atherosclerotic stenosis.PMID:38714134 | DOI:10.1016/j.ejrad.2024.111495 (Source: Atherosclerosis)
Source: Atherosclerosis - May 7, 2024 Category: Cardiology Authors: Feng Ouyang Jie Liu Qin Wu Jingting Chen Zihe Xu Lianjiang Lv Bo Wang Jian Li Nianzu Yu Xianjun Zeng Source Type: research
Relationship between fibroblast growth factor in plasma and carotid plaque neovascularization: a pilot study
CONCLUSION: This pilot study suggest the potential of FGF-23 as a valuable marker for neovascularization and atherosclerotic carotid plaque instability as a risk factor for ischemic stroke. Further research involving larger cohorts and prospective data is necessary to understand FGF-23's role in this context comprehensively.PMID:38711510 | PMC:PMC11070475 | DOI:10.3389/fimmu.2024.1385377 (Source: Atherosclerosis)
Source: Atherosclerosis - May 7, 2024 Category: Cardiology Authors: Mahtab Zamani Karolina Skagen Beate Lindberg Vigdis Bjerkeli P ål Aukrust Bente Halvorsen Mona Skjelland Source Type: research
Robustness and classification capabilities of MRI radiomic features in identifying carotid plaque vulnerability
CONCLUSIONS: The combination of MRI-based radiomic features and lesion morphological and compositional parameters provided added value to the reference-standard risk assessment for carotid atherosclerosis. This may improve future risk stratification for individuals at risk of major adverse ischemic cerebrovascular events.PMID:38711198 | DOI:10.1093/bjr/tqae057 (Source: Atherosclerosis)
Source: Atherosclerosis - May 7, 2024 Category: Cardiology Authors: Zakaria Meddings Leonardo Rundo Umar Sadat Xihai Zhao Zhongzhao Teng Martin J Graves Source Type: research
An Assessment of the Prevalence and Risk Factors of Hypertensive Crisis in Patients Who Visited the Emergency Outpatient Department (EOPD) at Adama Hospital Medical College, Adama, Oromia, Ethiopia: A 6-Month Prospective Study
Conclusions and Recommendations. Hypertensive crises are one of the most prevalent reasons for EOPD admission and are linked to significant consequences. At presentation, most of the study subjects were known hypertension patients. Diabetes mellitus was discovered to be a comorbid condition in one-quarter of them. Although more than half of the patients had improved, the death rate still remained high. Infrastructure and capacity building to provide hospitals with the requisite baseline investigations are among the government's recommendations. Health practitioners are expected to make improvements, such as by educating th...
Source: International Journal of Hypertension - May 7, 2024 Category: Cardiology Authors: Abel Tezera Abebe Yabets Tesfaye Kebede Bekri Delil Mohammed Source Type: research
Regulating NCOA4-Mediated Ferritinophagy for Therapeutic Intervention in Cerebral Ischemia-Reperfusion Injury
Neurochem Res. 2024 May 7. doi: 10.1007/s11064-024-04146-4. Online ahead of print.ABSTRACTIschemic stroke presents a global health challenge, necessitating an in-depth comprehension of its pathophysiology and therapeutic strategies. While reperfusion therapy salvages brain tissue, it also triggers detrimental cerebral ischemia-reperfusion injury (CIRI). In our investigation, we observed the activation of nuclear receptor coactivator 4 (NCOA4)-mediated ferritinophagy in an oxygen-glucose deprivation/reoxygenation (OGD/R) model using HT22 cells (P < 0.05). This activation contributed to oxidative stress (P < 0.05), enh...
Source: Cell Research - May 7, 2024 Category: Cytology Authors: Lan Zhao Yanan Li Wei Wang Xue Qi Su Wang Wenqin Song Ting Li Wenwei Gao Source Type: research
Early functional factors for predicting outcome of independence in daily living after stroke: a decision tree analysis
CONCLUSION: The ability to perform "sitting-to-standing" and visuomotor organization functions at the beginning of rehabilitation emerged as the most significant predictors for achieving successful basic activities of daily living on discharge after stroke.PMID:38712968 | DOI:10.2340/jrm.v56.35095 (Source: Journal of Rehabilitation Medicine)
Source: Journal of Rehabilitation Medicine - May 7, 2024 Category: Rehabilitation Authors: Heegoo Kim Chanmi Lee Nayeong Kim Eunhye Chung HyeongMin Jeon Seyoung Shin MinYoung Kim Source Type: research
