Differential ischemic stroke risk linked to novel subtypes of type 2 diabetes: insights from a Mendelian randomization analysis
ConclusionsOur study highlights distinct causal links between specific type 2 diabetes subtypes and ischemic stroke risks, emphasizing the importance of subtype-specific prevention and treatment strategies. (Source: Endocrine)
Source: Endocrine - April 30, 2024 Category: Endocrinology Source Type: research

Utility and usability of a wearable system and progressive-challenge cued exercise program for encouraging use of the more involved arm at-home after stroke —a feasibility study with case reports
Understanding the role of adherence to home exercise programs for survivors of stroke is critical to ensure patients perform prescribed exercises and maximize effectiveness of recovery. (Source: Journal of NeuroEngineering and Rehabilitation)
Source: Journal of NeuroEngineering and Rehabilitation - April 30, 2024 Category: Rehabilitation Authors: Jake Horder, Leigh A. Mrotek, Maura Casadio, Kimberly D. Bassindale, John McGuire and Robert A. Scheidt Tags: Research Source Type: research

All Three Supersystems —Nervous, Vascular, and Immune—Contribute to the Cortical Infarcts After Subarachnoid Hemorrhage
AbstractThe recently published DISCHARGE-1 trial supports the observations of earlier autopsy and neuroimaging studies that almost 70% of all focal brain damage after aneurysmal subarachnoid hemorrhage are anemic infarcts of the cortex, often also affecting the white matter immediately below. The infarcts are not limited by the usual vascular territories. About two-fifths of the ischemic damage occurs within  ~ 48 h; the remaining three-fifths are delayed (within ~ 3 weeks). Using neuromonitoring technology in combination with longitudinal neuroimaging, the entire sequence of both early and delayed cortical infar...
Source: Translational Stroke Research - April 30, 2024 Category: Neurology Source Type: research

Unsupervised Machine Learning Revealed that Repeat Transcranial Magnetic Stimulation is More Suitable for Stroke Patients with Statin
ConclusionStroke patients undergoing rTMS treatment taking statins exhibited greater MEP, FFO, and changes in FMA. Statin intake was associated with a better prognosis in these patients. (Source: Neurology and Therapy)
Source: Neurology and Therapy - April 30, 2024 Category: Neurology Source Type: research

COVID-19 Pandemic and Stroke Care in Patients With Dementia Compared to Other Stroke Patients
The primary objective of this study was to examine the impact of the COVID-19 pandemic on the quality of stroke care for patients with preexisting dementia, compared with patients who had only stroke. The secondary aim was to investigate how the quality of stroke care changed during the pandemic and post-pandemic periods compared with the pre-pandemic period in patients with preexisting dementia. (Source: Journal of the American Medical Directors Association)
Source: Journal of the American Medical Directors Association - April 30, 2024 Category: Health Management Authors: Tamar Abzhandadze, Minh Tuan Hoang, Minjia Mo, Shayan Mostafaei, Pol Grau Jurado, Hong Xu, Kristina Johnell, Mia Von Euler, Maria Eriksdotter, Sara Garcia-Ptacek Tags: Original Study Source Type: research

Role of Stroke Scales and Scores in Cerebrovascular Disease
This article provides a comprehensive review of widely utilized stroke scales in both routine clinical settings and research. These scales are crucial for planning treatment, predicting outcomes, and helping stroke patients recover. They also play a pivotal role in planning, executing, and comprehending stroke clinical trials. Each scale presents distinct advantages and limitations, and the authors explore these aspects within the article. The authors' intention is to provide the reader with practical insights for a clear understanding of these scales, and their effective use in their clinical practice. (Source: Neurologic Clinics)
Source: Neurologic Clinics - April 30, 2024 Category: Neurology Authors: Violiza Inoa, Nitin Goyal Source Type: research

An Artificial Intelligence-Driven Approach for Automatic Evaluation of Right-to-Left Shunt Grades in Saline-Contrasted Transthoracic Echocardiography
In this study, we proposed an artificial intelligence (AI)-based algorithm designed to automatically detect microbubbles in scTTE images and evaluate right-to-left shunt grades. (Source: Ultrasound in Medicine and Biology)
Source: Ultrasound in Medicine and Biology - April 30, 2024 Category: Radiology Authors: Yajiao Li, Haipeng Chen, Ximeng Yang, Anjiao Peng, Shuxin Wang, Hui Wang, Zhongyuan Jiang, Jie Zhang, Yixue Peng, Lei Li, Lijia Zhuo, Mengyu Li, Leihao Sha, Bo Peng, Xiaoqing Liu, Lei Chen Tags: Original Contribution Source Type: research

Safety and efficacy of intravenous thrombolysis before mechanical thrombectomy in patients with atrial fibrillation
ConclusionIVT plus EVT leads to better functional outcomes and lower mortality in AIS-LVO patients with AF. Withholding IVT plus EVT from patients with AF alone may not be justified. (Source: Systematic Reviews)
Source: Systematic Reviews - April 30, 2024 Category: International Medicine & Public Health Source Type: research

The Effects of Alpha Linolenic Acid (Omega-3 Fatty Acid) on Tobacco Craving Intensity, Withdrawal Symptoms and Biochemical Markers in Tobacco Users
This study was registered at Clinical Trial Registry-India (http://www.ctri.nic.in) with reference no. CTRI202202040681 and was performed in accordance with the Declaration of Helsinki principles. (Source: Indian Journal of Clinical Biochemistry)
Source: Indian Journal of Clinical Biochemistry - April 30, 2024 Category: Biochemistry Source Type: research

Sensors, Vol. 24, Pages 2887: Subcranial Encephalic Temnograph-Shaped Helmet For Brain Stroke Monitoring
Solimene In this contribution, a wearable microwave imaging system for real-time monitoring of brain stroke in the post-acute stage is described and validated. The system exploits multistatic/multifrequency (only 50 frequency samples) data collected via a low-cost and low-complexity architecture. Data are collected by an array of only 16 antennas moved by pneumatic system. Phantoms, built from ABS material and filled with appropriate Triton X-100-based mixtures to mimic the different head human tissues, are employed for the experiments. The microwave system exploits the differential scattering measures and the Incohere...
Source: Sensors - April 30, 2024 Category: Biotechnology Authors: Antonio Cuccaro Angela Dell ’Aversano Bruno Basile Maria Antonia Maisto Raffaele Solimene Tags: Article Source Type: research

Endovascular Thrombectomy for Large Ischemic Strokes with ASPECTS 0 –2: a Meta-analysis of Randomized Controlled Trials
ConclusionThis meta-analysis suggests a  treatment effect of endovascular thrombectomy in specific patients with very low ASPECTS of 0–2, challenging the use of ASPECTS for treatment selection in acute ischemic stroke due to large vessel occlusion. An individual patient meta-analysis of RCTs would strengthen evidence in the treatment o f patients with ASPECTS of 0–2.Graphic abstract (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - April 30, 2024 Category: Radiology Source Type: research

Outcomes with General Anesthesia Compared to Conscious Sedation for Endovascular Treatment of Medium Vessel Occlusions: Results of an International Multicentric Study
ConclusionAnaesthetic strategy in MeVOs does not influence favorable outcomes or final successful recanalization rates, however, GA may be associated with an increased risk of sICH and mortality. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - April 30, 2024 Category: Radiology Source Type: research

Clinical and laboratory features of sickle cell disease s/d punjab: impact of hbf and hydroxyurea
Conclusion: SD Punjab is the third most common SCD genotype in Oman and was associated with recurrent VOC, ACS, AVN, and gall stones comparable to other SCD genotypes. Patients with> 3 VOC/year had significantly increased incidence of Stroke, AVN, and gallstones. However, HU was not associated with improved prognosis and better survival in this cohort of patients.Keywords: Sickle Cell Disease; Haemoglobin SD Punjab; vaso-occlusive crises; acute chest syndrome; Avascular Necrosis; HbF; hydroxyurea. (Source: Mediterranean Journal of Hematology and Infectious Diseases)
Source: Mediterranean Journal of Hematology and Infectious Diseases - April 30, 2024 Category: Hematology Authors: r. Salam Al-Kindi, Isra Al-Busaidi, Anil Pathare Source Type: research

Haemodynamic monitoring during noncardiac surgery: past, present, and future
AbstractDuring surgery, various haemodynamic variables are monitored and optimised to maintain organ perfusion pressure and oxygen delivery – and to eventually improve outcomes. Important haemodynamic variables that provide an understanding of most pathophysiologic haemodynamic conditions during surgery include heart rate, arterial pressure, central venous pressure, pulse pressure variation/stroke volume variation, stroke volume, and cardiac output. A basic physiologic and pathophysiologic understanding of these haemodynamic variables and the corresponding monitoring methods is essential. We therefore revisit the pathoph...
Source: Journal of Clinical Monitoring and Computing - April 30, 2024 Category: Information Technology Source Type: research

Dietary inflammatory index is associated with severe depression in older adults with stroke: a cross-sectional study
In conclusion, an increase in DII score was associated with a higher likelihood of severe depression in older adults with stroke.PMID:38679919 | DOI:10.1017/S0007114524000850 (Source: The British Journal of Nutrition)
Source: The British Journal of Nutrition - April 29, 2024 Category: Nutrition Authors: Panpan Zhang Yubin Wang Xia Xie Yuan Gao Yurong Zhang Source Type: research