Visual imagery deficits in posterior cortical atrophy
Cogn Neuropsychol. 2024 May 2:1-16. doi: 10.1080/02643294.2024.2346362. Online ahead of print.ABSTRACTVisual imagery has a close overlapping relationship with visual perception. Posterior cortical atrophy (PCA) is a neurodegenerative syndrome marked by early impairments in visuospatial processing and visual object recognition. We asked whether PCA would therefore also be marked by deficits in visual imagery, tested using objective forced-choice questionnaires, and whether imagery deficits would be selective for certain properties. We recruited four patients with PCA and a patient with integrative visual agnosia due to bila...
Source: Cognitive Neuropsychology - May 2, 2024 Category: Psychiatry & Psychology Authors: Connor D Dietz Andrea Albonico Jeremy J Tree Jason J S Barton Source Type: research
Combining echocardiography and fluoroscopy imaging in real time for left atrial appendage occlusion - single center experience from Poland
CONCLUSIONS: This study marks the inaugural application of FI in Polish LAAO procedures. FI, offering enhanced visualization and reduced procedure times, holds promise in improving patient safety and treatment efficacy. We recommend its consideration as a standard visualization technique for LAAO procedures.PMID:38693977 | PMC:PMC11059017 | DOI:10.5114/kitp.2024.138575 (Source: Polish Journal of Cardio-Thoracic Surgery)
Source: Polish Journal of Cardio-Thoracic Surgery - May 2, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Marian Burysz Jakub Batko Michalina Helena Malec-Litwinowicz Mariusz Kowalewski Rados ław Adam Litwinowicz Aleksandra Burysz Łukasz Graczykowski Wojciech Olejek Source Type: research
Are we ready for new strategies to prevent stroke in children with sickle cell disease?
Haematologica. 2024 May 2. doi: 10.3324/haematol.2024.285328. Online ahead of print.ABSTRACTNot available.PMID:38695140 | DOI:10.3324/haematol.2024.285328 (Source: Haematologica)
Source: Haematologica - May 2, 2024 Category: Hematology Authors: Giovanna Russo Raffaella Colombatti Source Type: research
Utilizing network pharmacology, molecular docking, and animal models to explore the therapeutic potential of the WenYang FuYuan recipe for cerebral ischemia-reperfusion injury through AGE-RAGE and NF- κB/p38MAPK signaling pathway modulation
CONCLUSION: This study utilized network pharmacology, molecular docking, and animal experiments to identify the potential mechanism of the WenYang FuYuan recipe, which may be associated with the regulation of the AGE-RAGE signaling pathway and the inhibition of target proteins and mRNAs in the downstream NF-kB/p38MAPK pathway.PMID:38697555 | DOI:10.1016/j.exger.2024.112448 (Source: Experimental Gerontology)
Source: Experimental Gerontology - May 2, 2024 Category: Geriatrics Authors: Ding Zhang Hongling Qin Wei Chen Junjun Xiang Minghe Jiang Ling Zhang Keqing Zhou Yueqiang Hu Source Type: research
IL-1 β Inhibition Partially Negates the Beneficial Effects of Diet-Induced Atherosclerosis Regression in Mice
CONCLUSIONS: Taken together, IL-1β appears to be required for the maintenance of standard laboratory diet-induced reductions in plaque burden and increases in multiple indices of plaque stability.PMID:38695167 | DOI:10.1161/ATVBAHA.124.320800 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - May 2, 2024 Category: Cardiology Authors: Santosh Karnewar Vaishnavi Karnewar Rebecca Deaton Laura S Shankman Ernest D Benavente Corey M Williams Xenia Bradley Gabriel F Alencar Gamze B Bulut Sara Kirmani Richard A Baylis Eli R Zunder Hester M den Ruijter Gerard Pasterkamp Gary K Owens Source Type: research
Subjects with carotid webs demonstrate pro-thrombotic hemodynamics compared to subjects with carotid atherosclerosis
Sci Rep. 2024 May 2;14(1):10092. doi: 10.1038/s41598-024-60666-7.ABSTRACTCarotid artery webs (CaW) are non-atherosclerotic projections into the vascular lumen and have been linked to up to one-third of cryptogenic strokes in younger patients. Determining how CaW affects local hemodynamics is essential for understanding clot formation and stroke risk. Computational fluid dynamics simulations were used to investigate patient-specific hemodynamics in carotid artery bifurcations with CaW, bifurcations with atherosclerotic lesions having a similar degree of lumen narrowing, and with healthy carotid bifurcations. Simulations wer...
Source: Atherosclerosis - May 2, 2024 Category: Cardiology Authors: Retta El Sayed Carissa J Lucas Hannah L Cebull Fadi B Nahab Diogo C Haussen Jason W Allen John N Oshinski Source Type: research
Utilizing network pharmacology, molecular docking, and animal models to explore the therapeutic potential of the WenYang FuYuan recipe for cerebral ischemia-reperfusion injury through AGE-RAGE and NF- κB/p38MAPK signaling pathway modulation
CONCLUSION: This study utilized network pharmacology, molecular docking, and animal experiments to identify the potential mechanism of the WenYang FuYuan recipe, which may be associated with the regulation of the AGE-RAGE signaling pathway and the inhibition of target proteins and mRNAs in the downstream NF-kB/p38MAPK pathway.PMID:38697555 | DOI:10.1016/j.exger.2024.112448 (Source: Atherosclerosis)
Source: Atherosclerosis - May 2, 2024 Category: Cardiology Authors: Ding Zhang Hongling Qin Wei Chen Junjun Xiang Minghe Jiang Ling Zhang Keqing Zhou Yueqiang Hu Source Type: research
Multiwavelength laser diode based portable photoacoustic and ultrasound imaging system for point of care applications
J Biophotonics. 2024 May 2:e202400058. doi: 10.1002/jbio.202400058. Online ahead of print.ABSTRACTVascular diseases are a leading cause of death and disability worldwide. Despite having precursor conditions like peripheral arterial disease (PAD), they are often only diagnosed after the onset of stroke or heart attack. Low-cost, portable, noninvasive, point-of-care (POC), label-free assessment of deep vascular function benefits PAD diagnosis, especially in resource poor settings of the world. Doppler ultrasound-based blood flow measurements can diagnose PAD, albeit with limited sensitivity and specificity. To overcome this,...
Source: Atherosclerosis - May 2, 2024 Category: Cardiology Authors: Mahaan Mitra Abigail Haworth Prameth Gaddale Faisal Badran Nuzhath Lagno Colette Pameijer Faisal Aziz Sri-Rajasekhar Kothapalli Source Type: research
IL-1beta Inhibition Partially Negates the Beneficial Effects of Diet-Induced Atherosclerosis Regression in Mice
CONCLUSIONS: Taken together, IL-1β appears to be required for the maintenance of standard laboratory diet-induced reductions in plaque burden and increases in multiple indices of plaque stability.PMID:38695167 | DOI:10.1161/ATVBAHA.124.320800 (Source: Atherosclerosis)
Source: Atherosclerosis - May 2, 2024 Category: Cardiology Authors: Santosh Karnewar Vaishnavi Karnewar Rebecca Deaton Laura S Shankman Ernest D Benavente Corey M Williams Xenia Bradley Gabriel F Alencar Gamze B Bulut Sara Kirmani Richard A Baylis Eli R Zunder Hester M den Ruijter Gerard Pasterkamp Gary K Owens Source Type: research
Baseline characteristics and outcome of stroke patients after endovascular therapy according to previous symptomatic vascular disease and sex
CONCLUSIONS: Previous vascular events increased the risk of in-hospital complications and poorer outcome in the analyzed patients with EVT-eligible LVO-AIS. Our findings may support risk assessment in these stroke patients and could contribute to the design of future studies.PMID:38694775 | PMC:PMC11061446 | DOI:10.3389/fneur.2024.1293905 (Source: Atherosclerosis)
Source: Atherosclerosis - May 2, 2024 Category: Cardiology Authors: Marieta Peycheva Giovanna Padlina Kotryna Genceviciute Marina P Krasteva Anna Boronylo Martina B Goeldlin Madlaine M üller Elena S Wenz Mandy D M üller Helly Hammer Philipp B ücke Sandra Bigi Barbara Goeggel Simonetti Angelika Hoffmann Roza M Umarova S Source Type: research
Anti-coagulants-induced intracranial hemorrhage managed with decompressive craniectomy: a case report of lesson learned
CONCLUSION: In the background of the low prevalence of OACs-induced ICH, there is an absence of a robust guiding treatment protocol. Furthermore, there exist minimal reported cases which underwent surgical intervention and resulted in a good prognosis.PMID:38694382 | PMC:PMC11060273 | DOI:10.1097/MS9.0000000000001996 (Source: Annals of Medicine)
Source: Annals of Medicine - May 2, 2024 Category: Internal Medicine Authors: Sagun Ghimire Shikher Shrestha Dinuj Shrestha Ananta Maharjan Bibek Jaiswal Prabin Chaudhary Sharon Sherpa Source Type: research
Factor Xa inhibitors vs. warfarin in patients with Hughes syndrome: a systematic review and meta-analysis of randomized controlled trials
CONCLUSION: Factor Xa inhibitors exhibited an increased risk of stroke among patients with Hughes syndrome. In addition, although not significant, the higher RRs among patients on factor Xa inhibitors may indicate a higher risk of thrombotic events associated with factor Xa inhibitors.PMID:38694373 | PMC:PMC11060306 | DOI:10.1097/MS9.0000000000001999 (Source: Annals of Medicine)
Source: Annals of Medicine - May 2, 2024 Category: Internal Medicine Authors: Ali Mohtashim Aima Azhar Saad Mazhar Deepa Devi Muhammad Danial Dhruvilkumar Patel Owais Khan Anushka Andani Muhammad Mohib Khan Shahzaib Samad Aena Qureshi Hafsa Ali Umer Ejaz Sayed Jawad Source Type: research
Efficacy and outcomes of antiplatelet therapy versus oral anticoagulants in patients undergoing transcatheter aortic valve replacement: a systematic review and meta-analysis
CONCLUSIONS: Although the risk of valve thrombosis increased in patients receiving APT, the risk of other endpoints was comparable between the two groups.PMID:38694361 | PMC:PMC11060210 | DOI:10.1097/MS9.0000000000001908 (Source: Annals of Medicine)
Source: Annals of Medicine - May 2, 2024 Category: Internal Medicine Authors: Aman Goyal Fatima Qayyum Abbasi Muhammad Daoud Tariq Sai Gautham Kanagala Mah I Kan Changez Darsh Safi Jawad Basit Samia Aziz Sulaiman Mohammed Dheyaa Marsool Marsool Mohamed Daoud Amir H Sohail Source Type: research
Short-term cervical spinal cord stimulation for central post-stroke pain: a case report and literature review
CONCLUSION: A potential role of spinal cord stimulation in the treatment of post-stroke pain is proposed in combined with traditional medication or other neuromodulation strategies, to achieve better control of pain in the future.PMID:38694358 | PMC:PMC11060234 | DOI:10.1097/MS9.0000000000002025 (Source: Annals of Medicine)
Source: Annals of Medicine - May 2, 2024 Category: Internal Medicine Authors: Xu Zhang Xuebin Yan Yuzhao Huang Haocheng Zhou Source Type: research
Combining echocardiography and fluoroscopy imaging in real time for left atrial appendage occlusion - single center experience from Poland
CONCLUSIONS: This study marks the inaugural application of FI in Polish LAAO procedures. FI, offering enhanced visualization and reduced procedure times, holds promise in improving patient safety and treatment efficacy. We recommend its consideration as a standard visualization technique for LAAO procedures.PMID:38693977 | PMC:PMC11059017 | DOI:10.5114/kitp.2024.138575 (Source: Polish Journal of Cardio-Thoracic Surgery)
Source: Polish Journal of Cardio-Thoracic Surgery - May 2, 2024 Category: Cardiovascular & Thoracic Surgery Authors: Marian Burysz Jakub Batko Michalina Helena Malec-Litwinowicz Mariusz Kowalewski Rados ław Adam Litwinowicz Aleksandra Burysz Łukasz Graczykowski Wojciech Olejek Source Type: research
