Glycemic and lipid control in patients with diabetes at time of myocardial infarction
CONCLUSION: We highlighted the poor glycemic and lipid control in high-risk CV patients. There is an urgent need to develop multidisciplinary approaches to optimize CV risk factors control to reduce myocardial infarction and strokes.PMID:38685473 | DOI:10.1016/j.pharma.2024.04.010 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - April 30, 2024 Category: Drugs & Pharmacology Authors: Christelle Lacqua H éloïse Adam Marianne Zeller Lucie Vadot Florence Bichat Maud Maza Yves Cottin Mathieu Boulin Source Type: research
Messenger RNAs in the Whole Blood of Male and Females after Acute Ischemic Stroke using Bioinformatics
CONCLUSIONS: This study identified gender-specific mRNA expression differences in the peripheral whole blood of AIS patients. The findings provide important insights into the molecular mechanisms underlying AIS in males and females.PMID:38687860 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 30, 2024 Category: Complementary Medicine Authors: Yanchao Wang Source Type: research
Preventable Premature Deaths from the Five Leading Causes of Death in Nonmetropolitan and Metropolitan Counties, United States, 2010-2022
This report provides estimates of preventable premature deaths for additional years (2010-2022).PERIOD COVERED: 2010-2022.DESCRIPTION OF SYSTEM: Mortality data for U.S. residents from the National Vital Statistics System were used to calculate preventable premature deaths from the five leading causes of death among persons aged <80 years. CDC's National Center for Health Statistics urban-rural classification scheme for counties was used to categorize the deaths according to the urban-rural county classification level of the decedent's county of residence (1: large central metropolitan [most urban], 2: large fringe metro...
Source: MMWR Surveill Summ - April 30, 2024 Category: Epidemiology Authors: Macarena C Garc ía Lauren M Rossen Kevin Matthews Gery Guy Katrina F Trivers Cheryll C Thomas Linda Schieb Michael F Iademarco Source Type: research
Atrial Septal Abnormalities and Cryptogenic Stroke: A Cross-Sectional Study
CONCLUSION: Based on our results, the prevalence of atrial septal abnormalities was relatively high. Considering these issues and the importance of preventing neurological accidents in patients, especially young people, it is recommended to always consider atrial septal disorders and, if diagnosed, to carry out the necessary treatment in this field.PMID:38685781 | DOI:10.2174/011871529X294809240415070950 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - April 30, 2024 Category: Drugs & Pharmacology Authors: Marzieh Aliramezany Mansoor Moazenzadeh Amin Sayyadi Khadijeh Mohammadi Hamidreza Barzegar Maryam Aliramezany Source Type: research
Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice
This study aimed to explore the effectiveness of EE on emotional disorders after cerebral ischemia and its underling mechanism. In this study, sensorimotor cortical infarction was induced by photothrombosis with stable infarct location and volume, resulting in motor dysfunction, anxiety and depression-like behaviors in mice, with decreased ALFF and ReHo values and decreased c-fos expression in the infarction area and adjacent regions. Seven days' EE treatment significantly improved motor function of contralateral forelimb and exhibited anxiolytic and antidepressant effects in infarcted mice. Compared to the mice housing in...
Source: Experimental Neurology - April 30, 2024 Category: Neurology Authors: Dan Huang Yunhui Fan Jingjun Zhang Qianfeng Wang Ming Ding Ruiqing Hou Kewei Yu Xiao Xiao Yi Wu Junfa Wu Source Type: research
Glycemic and lipid control in patients with diabetes at time of myocardial infarction
CONCLUSION: We highlighted the poor glycemic and lipid control in high-risk CV patients. There is an urgent need to develop multidisciplinary approaches to optimize CV risk factors control to reduce myocardial infarction and strokes.PMID:38685473 | DOI:10.1016/j.pharma.2024.04.010 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - April 30, 2024 Category: Drugs & Pharmacology Authors: Christelle Lacqua H éloïse Adam Marianne Zeller Lucie Vadot Florence Bichat Maud Maza Yves Cottin Mathieu Boulin Source Type: research
Messenger RNAs in the Whole Blood of Male and Females after Acute Ischemic Stroke using Bioinformatics
CONCLUSIONS: This study identified gender-specific mRNA expression differences in the peripheral whole blood of AIS patients. The findings provide important insights into the molecular mechanisms underlying AIS in males and females.PMID:38687860 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 30, 2024 Category: Complementary Medicine Authors: Yanchao Wang Source Type: research
Preventable Premature Deaths from the Five Leading Causes of Death in Nonmetropolitan and Metropolitan Counties, United States, 2010-2022
This report provides estimates of preventable premature deaths for additional years (2010-2022).PERIOD COVERED: 2010-2022.DESCRIPTION OF SYSTEM: Mortality data for U.S. residents from the National Vital Statistics System were used to calculate preventable premature deaths from the five leading causes of death among persons aged <80 years. CDC's National Center for Health Statistics urban-rural classification scheme for counties was used to categorize the deaths according to the urban-rural county classification level of the decedent's county of residence (1: large central metropolitan [most urban], 2: large fringe metro...
Source: MMWR Surveill Summ - April 30, 2024 Category: Epidemiology Authors: Macarena C Garc ía Lauren M Rossen Kevin Matthews Gery Guy Katrina F Trivers Cheryll C Thomas Linda Schieb Michael F Iademarco Source Type: research
Dorsal dentate gyrus mediated enriched environment-induced anxiolytic and antidepressant effects in cortical infarcted mice
This study aimed to explore the effectiveness of EE on emotional disorders after cerebral ischemia and its underling mechanism. In this study, sensorimotor cortical infarction was induced by photothrombosis with stable infarct location and volume, resulting in motor dysfunction, anxiety and depression-like behaviors in mice, with decreased ALFF and ReHo values and decreased c-fos expression in the infarction area and adjacent regions. Seven days' EE treatment significantly improved motor function of contralateral forelimb and exhibited anxiolytic and antidepressant effects in infarcted mice. Compared to the mice housing in...
Source: Experimental Neurology - April 30, 2024 Category: Neurology Authors: Dan Huang Yunhui Fan Jingjun Zhang Qianfeng Wang Ming Ding Ruiqing Hou Kewei Yu Xiao Xiao Yi Wu Junfa Wu Source Type: research
Atrial Septal Abnormalities and Cryptogenic Stroke: A Cross-Sectional Study
CONCLUSION: Based on our results, the prevalence of atrial septal abnormalities was relatively high. Considering these issues and the importance of preventing neurological accidents in patients, especially young people, it is recommended to always consider atrial septal disorders and, if diagnosed, to carry out the necessary treatment in this field.PMID:38685781 | DOI:10.2174/011871529X294809240415070950 (Source: Cardiovascular and Hematological Disorders Drug Targets)
Source: Cardiovascular and Hematological Disorders Drug Targets - April 30, 2024 Category: Drugs & Pharmacology Authors: Marzieh Aliramezany Mansoor Moazenzadeh Amin Sayyadi Khadijeh Mohammadi Hamidreza Barzegar Maryam Aliramezany Source Type: research
Messenger RNAs in the Whole Blood of Male and Females after Acute Ischemic Stroke using Bioinformatics
CONCLUSIONS: This study identified gender-specific mRNA expression differences in the peripheral whole blood of AIS patients. The findings provide important insights into the molecular mechanisms underlying AIS in males and females.PMID:38687860 (Source: Alternative Therapies in Health and Medicine)
Source: Alternative Therapies in Health and Medicine - April 30, 2024 Category: Complementary Medicine Authors: Yanchao Wang Source Type: research
Glycemic and lipid control in patients with diabetes at time of myocardial infarction
CONCLUSION: We highlighted the poor glycemic and lipid control in high-risk CV patients. There is an urgent need to develop multidisciplinary approaches to optimize CV risk factors control to reduce myocardial infarction and strokes.PMID:38685473 | DOI:10.1016/j.pharma.2024.04.010 (Source: Annales Pharmaceutiques Francaises)
Source: Annales Pharmaceutiques Francaises - April 30, 2024 Category: Drugs & Pharmacology Authors: Christelle Lacqua H éloïse Adam Marianne Zeller Lucie Vadot Florence Bichat Maud Maza Yves Cottin Mathieu Boulin Source Type: research
Targeting pyroptosis to treat ischemic stroke: From molecular pathways to treatment strategy
Int Immunopharmacol. 2024 Apr 29;133:112168. doi: 10.1016/j.intimp.2024.112168. Online ahead of print.ABSTRACTIschemic stroke is the primary reason for human disability and death, but the available treatment options are limited. Hence, it is imperative to explore novel and efficient therapies. In recent years, pyroptosis (a pro-inflammatory cell death characterized by inflammation) has emerged as an important pathological mechanism in ischemic stroke that can cause cell death through plasma membrane rupture and release of inflammatory cytokines. Pyroptosis is closely associated with inflammation, which exacerbates the infl...
Source: International Immunopharmacology - April 30, 2024 Category: Allergy & Immunology Authors: Lina Li Chonglin Shi Fang Dong Guangyu Xu Mingcheng Lei Feng Zhang Source Type: research
Preventable Premature Deaths from the Five Leading Causes of Death in Nonmetropolitan and Metropolitan Counties, United States, 2010-2022
This report provides estimates of preventable premature deaths for additional years (2010-2022).PERIOD COVERED: 2010-2022.DESCRIPTION OF SYSTEM: Mortality data for U.S. residents from the National Vital Statistics System were used to calculate preventable premature deaths from the five leading causes of death among persons aged <80 years. CDC's National Center for Health Statistics urban-rural classification scheme for counties was used to categorize the deaths according to the urban-rural county classification level of the decedent's county of residence (1: large central metropolitan [most urban], 2: large fringe metro...
Source: MMWR Surveill Summ - April 30, 2024 Category: Epidemiology Authors: Macarena C Garc ía Lauren M Rossen Kevin Matthews Gery Guy Katrina F Trivers Cheryll C Thomas Linda Schieb Michael F Iademarco Source Type: research
Automatic assessment of DWI-ASPECTS for acute ischemic stroke based on deep learning
CONCLUSIONS: This study proposed an automated model for ASPECTS scoring of patients with acute ischemic stroke based on DWI images. Experimental results show that the method of segmentation first and then classification is feasible. Our method has the potential to assist physicians in the Alberta Stroke Program with early CT scoring and clinical stroke diagnosis.PMID:38687043 | DOI:10.1002/mp.17101 (Source: Health Physics)
Source: Health Physics - April 30, 2024 Category: Physics Authors: Ting Fang Zhuoyun Jiang Yuxi Zhou Shouqiang Jia Jiaqi Zhao Shengdong Nie Source Type: research
