Cardiovascular Comorbidities and Inflammatory Bowel Disease: Causes and Consequences
This article discusses causes of CVD in IBD and strategies to modify the consequences.PMID:38682122 | PMC:PMC11047149 (Source: Atherosclerosis)
Source: Atherosclerosis - April 29, 2024 Category: Cardiology Authors: Preetika Sinh Raymond K Cross Source Type: research
The Roles of Circular RNAs in Ischemic Stroke through Modulating Neuroinflammation
This study reviews the current evidence on neuroinflammatory responses, the role of circRNAs in IS and their potential mechanisms in regulating inflammatory cells, and inflammatory factors affecting IS damage. This review lays a foundation for future clinical application of circRNAs as novel biomarkers and therapeutic targets.PMID:38682221 | DOI:10.31083/j.jin2304087 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Xin Gu Lingfei Li Biao Chen Yuyao Zhang Yongji Zhou Keqin Liu Wenqin Xia Xiaoqin Li Zheng Zhang Huanqing Shi Jinyu Huang Beibei Gao Lin Jiang Anwen Shao Congguo Yin Source Type: research
Effect of Pre-Antibiotic Use Before First Stroke Incidence on Recurrence and Mortality: A Longitudinal Study Using the Korean National Health Insurance Service Database
(Source: International Journal of General Medicine)
Source: International Journal of General Medicine - April 29, 2024 Category: General Medicine Tags: International Journal of General Medicine Source Type: research
Risk of Adverse Cardiovascular Outcomes in Postmenopausal Women with Inflammatory Bowel Disease
ConclusionsAmong postmenopausal women with IBD, risk of ischemic stroke may be higher than in non-IBD women. (Source: Digestive Diseases and Sciences)
Source: Digestive Diseases and Sciences - April 29, 2024 Category: Gastroenterology Source Type: research
Long-Term Accumulation of T Cytotoxic 1, T Cytotoxic 17, and T Cytotoxic 17/1 Cells in the Brain Contributes to Microglia-Mediated Chronic Neuroinflammation After Ischemic Stroke
AbstractPost-stroke neuroinflammation affects the damage and recovery of neurological functions. T cells including CD8+ T cells were present in the ipsilateral hemisphere in the subacute and late phases of ischemic stroke. However, the potential roles of CD8+ T cell subsets in the progression of neuroinflammation have not been characterized. In the current mouse transient middle cerebral artery occlusion model, we investigated the existence of CD8+ T cell subsets in the ipsilateral hemisphere in the subacute and late phases of stroke. We found that ipsilateral CD8+ T cells were present on post-stroke day 3 and increased on...
Source: NeuroMolecular Medicine - April 29, 2024 Category: Neurology Source Type: research
Diagnostic Accuracy for Detecting Atrial Fibrillation Using a Novel Machine Learning Algorithm in a Blood Pressure Monitor
Early detection of atrial fibrillation (AF) is key for preventing strokes. Blood pressure monitors (BPMs) with built-in AF screening features have the potential for early detection at home. Recently, two BPMs (HEM-7371T1-AZ and HEM-7372T1-AZAZ, OMRON HEALTHCARE Co., Ltd.) which share a novel AF screening feature have been developed. Their AF screening feature utilizes an algorithm which incorporates machine learning, with the potential to improve diagnostic accuracy. (Source: Heart Rhythm)
Source: Heart Rhythm - April 29, 2024 Category: Cardiology Authors: Matthew Janik, George Raad, George Nijmeh, Matthew O ’Steen, Jason Rasmussen Source Type: research
SUPRAMAX-study: supramaximal resection versus maximal resection for glioblastoma patients: study protocol for an international multicentre prospective cohort study (ENCRAM 2201)
This study is an international, multicentre, prospective, two-arm cohort study of observational nature. Consecutive glioblastoma patients will be operated with SMR or maximal resection at a 1:1 ratio. Primary endpoints are (1) overall survival and (2) proportion of patients with National Institute of Health Stroke Scale deterioration at 6 weeks, 3 months and 6 months postoperatively. Secondary endpoints are (1) residual CE and NCE tumour volume on postoperative T1-contrast and FLAIR (Fluid-attenuated inversion recovery) MRI scans; (2) progression-free survival; (3) receipt of adjuvant therapy with chemotherapy and radiothe...
Source: BMJ Open - April 29, 2024 Category: General Medicine Authors: Gerritsen, J. K. W., Young, J. S., Chang, S. M., Krieg, S. M., Jungk, C., van den Bent, M. J., Satoer, D. D., Ille, S., Schucht, P., Nahed, B. V., Broekman, M. L. D., Berger, M., De Vleeschouwer, S., Vincent, A. J. P. E. Tags: Open access, Oncology Source Type: research
Lifetime costs of alcohol consumption in Thailand: protocol for an incidence-based cost-of-illness study using Markov model
Introduction
Several prevalence-based cost-of-illness (COI) studies have been conducted to estimate the economic burden of alcohol consumption borne by a particular society in a given year. Yet there are few studies examining the economic costs incurred by an individual drinker over his/her lifetime. Thus, this study aims to estimate the costs incurred by an individual drinker’s alcohol consumption over his or her lifetime in Thailand.
Methods and analysis
An incidence-based COI approach will be employed. To project individuals’ associated costs over a lifetime, a Markov modelling technique will be used. The f...
Source: BMJ Open - April 29, 2024 Category: General Medicine Authors: Luangsinsiri, C., Thavorncharoensap, M., Chaikledkaew, U., Pattanaprateep, O., Sornpaisarn, B., Rehm, J. Tags: Open access, Health economics Source Type: research
Differential Use of Glycoprotein IIb/IIIa Inhibitors with Bivalirudin in Patients with STEMI Undergoing PCI: A Systematic Review and Meta-Analysis
ConclusionOverall, our findings suggest that bivalirudin may be a more efficacious intervention than heparin for reducing certain adverse events in patients with STEMI undergoing primary PCI. (Source: American Journal of Cardiovascular Drugs)
Source: American Journal of Cardiovascular Drugs - April 29, 2024 Category: Cardiology Source Type: research
Comparison of the efficacy and safety of warfarin anticoagulation and left atrial appendage transcatheter occlusion in the treatment of non-valvular atrial fibrillation and investigation of ET-1, hs-CRP and PDGFs
This study compared the therapeutic effect and safety between warfarin anticoagulation and percutaneous left atrial appendage transcatheter occlusion (PLAATO) in non-valvular atrial fibrillation (NVAF). A total of 110 patients were selected and assigned to Control group (n=55) and Observation group (n=55). The control patients were used warfarin, while the observation patients were performed PLAATO. The coagulation function, stroke and bleeding scores were compared between the two groups at different times. Left ventricular function before therapy and 1 year after therapy and adverse events during follow-up were compared b...
Source: Cellular and Molecular Biology - April 28, 2024 Category: Molecular Biology Authors: Yujie Zhang Yali Yao Ling Tao Tao Du Binbin Jia Mi Zhou Zhen Zhang Source Type: research
Association of ambient ozone exposure and greenness exposure with hemorrhagic stroke mortality at different times: A cohort study in Shandong Province, China
This study aimed to investigate the association between long-term exposure to ambient ozone, greenness, and mortality from HS using exposure metrics at different times. We also examined whether greenness exposure modified the relationship between ozone exposure and mortality due to HS. The study population consisted of 45771 participants aged ≥40 y residing in 20 counties in Shandong Province who were followed up from 2013 to 2019. Ozone exposure metrics (annual mean and warm season) and the normalized difference a measure of greenness exposure, were calculated. The relationship between environmental exposures (ozone and...
Source: Ecotoxicology and Environmental Safety - April 28, 2024 Category: Environmental Health Authors: Chengrong Liu Bingyin Zhang Chao Liu Yingying Zhang Ke Zhao Peiyao Zhang Meihui Tian Zilong Lu Xiaolei Guo Xianjie Jia Source Type: research
Comparison of the efficacy and safety of warfarin anticoagulation and left atrial appendage transcatheter occlusion in the treatment of non-valvular atrial fibrillation and investigation of ET-1, hs-CRP and PDGFs
This study compared the therapeutic effect and safety between warfarin anticoagulation and percutaneous left atrial appendage transcatheter occlusion (PLAATO) in non-valvular atrial fibrillation (NVAF). A total of 110 patients were selected and assigned to Control group (n=55) and Observation group (n=55). The control patients were used warfarin, while the observation patients were performed PLAATO. The coagulation function, stroke and bleeding scores were compared between the two groups at different times. Left ventricular function before therapy and 1 year after therapy and adverse events during follow-up were compared b...
Source: Cellular and Molecular Biology - April 28, 2024 Category: Molecular Biology Authors: Yujie Zhang Yali Yao Ling Tao Tao Du Binbin Jia Mi Zhou Zhen Zhang Source Type: research
Association of ambient ozone exposure and greenness exposure with hemorrhagic stroke mortality at different times: A cohort study in Shandong Province, China
This study aimed to investigate the association between long-term exposure to ambient ozone, greenness, and mortality from HS using exposure metrics at different times. We also examined whether greenness exposure modified the relationship between ozone exposure and mortality due to HS. The study population consisted of 45771 participants aged ≥40 y residing in 20 counties in Shandong Province who were followed up from 2013 to 2019. Ozone exposure metrics (annual mean and warm season) and the normalized difference a measure of greenness exposure, were calculated. The relationship between environmental exposures (ozone and...
Source: Ecotoxicology and Environmental Safety - April 28, 2024 Category: Environmental Health Authors: Chengrong Liu Bingyin Zhang Chao Liu Yingying Zhang Ke Zhao Peiyao Zhang Meihui Tian Zilong Lu Xiaolei Guo Xianjie Jia Source Type: research
