Utility of Time-Variant Multiphase CTA Color Maps in Outcome Prediction for Acute Ischemic Stroke Due to Anterior Circulation Large Vessel Occlusion
ConclusionIn this study, collateral extent assessment on time-variant mCTA maps improved prediction of good outcome and has similar value in predicting follow-up infarct volume compared to conventional mCTA collateral grading. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - September 25, 2020 Category: Radiology Source Type: research

55. Jahrestagung der Deutschen Gesellschaft f ür Neuroradiologie e.V.
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - September 23, 2020 Category: Radiology Source Type: research

Standard Diffusion-weighted MRI for the Diagnosis of Central Retinal Artery Occlusion
ConclusionsRetinal diffusion restrictions were present in a  majority of CRAO patients and detectable with reasonable sensitivity, high specificity and substantial inter-rater reliability. Further studies are necessary to study time dependency of retinal diffusion restrictions, improve image quality and investigate the reliability of retinal DWI to discern CRAO from other causes of acute loss of vision. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - September 16, 2020 Category: Radiology Source Type: research

pCONUS for Distal Artery Protection During Complex Aneurysm Treatment by Endovascular Parent Vessel Occlusion —A Technical Nuance
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - September 7, 2020 Category: Radiology Source Type: research

Reasons for Failed Mechanical Thrombectomy in Posterior Circulation Ischemic Stroke Patients
AbstractBackground and PurposeTo determine reasons for failed recanalization in mechanical thrombectomy (MT) of the posterior circulation.MethodsRetrospective single center analysis of reasons for MT failure in the posterior circulation. Failed MTs were categorized according to the reason for procedure failure in failed vascular access, failed passage of the target vessel occlusion and MT failure after passing the occluded target vessel. Patient characteristics were compared between failed and successful MT.ResultsPatients with failed MT (30/218 patients, 13.8%) were categorized into futile vascular access (13/30, 43.3%), ...
Source: Klinische Neuroradiologie - September 7, 2020 Category: Radiology Source Type: research

Role of Susceptibility-Weighted Imaging in Detecting Retinal Hemorrhages in Children with Head Trauma
ConclusionOur results suggest that SWI is a  useful diagnostic tool for detection of RH in pediatric head trauma in whom DFE is difficult to perform. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - August 5, 2020 Category: Radiology Source Type: research

Casper vs. Closed-Cell Stent
ConclusionThe Casper stents did not show superiority in the rate of incidence, number and size of new silent ischemic brain lesions detect by DW-MRI when compared to close cell stents during CAS under distal EPD. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - August 3, 2020 Category: Radiology Source Type: research

Leave Nothing Behind: Treatment of Intracranial Atherosclerotic Disease with Drug-Coated Balloon Angioplasty
ConclusionIn this study, the application of DCBs to treat ICAD patients was feasible and safe. A  larger scale clinical trial is warranted to further evaluate the safety and efficacy of this treatment. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - July 27, 2020 Category: Radiology Source Type: research

Microstructural Alterations Analogous to Accelerated Aging of the Cerebral Cortex in Carotid Occlusive Disease
AbstractPurposeTo investigate cortical thickness and cortical quantitative T2  values as imaging markers of microstructural tissue damage in patients with unilateral high-grade internal carotid artery occlusive disease (ICAOD).MethodsA total of 22  patients with ≥70% stenosis (mean age 64.8 years) and 20 older healthy control subjects (mean age 70.8 years) underwent structural magnetic resonance imaging (MRI) and high-resolution quantitative (q)T2 mapping. Generalized linear mixed models (GLMM) controlling for age and white matter lesio n volume were employed to investigate the effect of ICAOD o...
Source: Klinische Neuroradiologie - July 7, 2020 Category: Radiology Source Type: research

Societies ‘ Communications
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - June 23, 2020 Category: Radiology Source Type: research

neuroRAD 2020 Virtual
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - June 1, 2020 Category: Radiology Source Type: research

Antiplatelet Drugs for Neurointerventions: Part  1 Clinical Pharmacology
AbstractThe development of endovascular treatment for intracranial aneurysms has established new techniques such as balloon and stent-assistance, flow diversion and endosaccular occlusion devices. Antiplatelet treatment is an important aspect to reduce risk of thrombus formation on microcatheters and implanted devices when utilizing these methods. It is particularly relevant for flow diverting stents to prevent early and late stent thrombosis. Consideration of platelet physiology and appropriate selection of antiplatelet medication is important as platelet dysfunction drives many of the pathological processes and complicat...
Source: Klinische Neuroradiologie - May 18, 2020 Category: Radiology Source Type: research

Sequelae of Premature Birth in Young Adults
This article aimed at filling this knowledge gap by (1)  qualitatively describing routine imaging findings in prematurely born adults, (2) evaluating measures for routine image interpretation and (3) investigating the impact of perinatal variables related to premature birth.MethodsIn this study two board-certified radiologists assessed T1-weighted and FLAIR-weighted images of 100 prematurely born adults born very preterm (VP
Source: Klinische Neuroradiologie - April 14, 2020 Category: Radiology Source Type: research

Two Cases of Symptomatic Carotid Web Treated by Carotid Artery Stenting
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - April 14, 2020 Category: Radiology Source Type: research

Differences in Safety and Efficacy of Endovascular Treatment for Acute Ischemic Stroke
ConclusionThis propensity score analysis demonstrated that the EVT patients with acute ICAD-related MCA M1 occlusion had similar angiographic and clinical outcomes compared to those with M1 embolism on a  similar baseline condition. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - April 1, 2020 Category: Radiology Source Type: research

Automated Meningioma Segmentation in Multiparametric MRI
ConclusionDeep learning-based automated segmentation yielded high segmentation accuracy, comparable to manual interreader variability. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - February 14, 2020 Category: Radiology Source Type: research

Single Center Experience in Stent-Assisted Coiling of Complex Intracranial Aneurysms Using Low-Profile Stents
ConclusionUsing the ACCLINO ® and ACCLINO® flex stent system is a feasible and effective procedure with an acceptable safety profile. Initial and follow-up angiographic results were satisfactory. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - February 12, 2020 Category: Radiology Source Type: research

Correction to: Long-term Outcome of Angioplasty Using a  Wingspan Stent, Post-Stent Balloon Dilation and Aggressive Restenosis Management for Intracranial Arterial Stenosis
Correction to:Clin Neuroradiol 2019https://doi.org/10.1007/s00062-019-00793-1The original version of this article unfortunately contained some mistakes. The Institutional Review Board number was given wrongly in the Methods/Participants section and in the Compliance with ethical guidelines/Ethical (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - February 7, 2020 Category: Radiology Source Type: research

Review of Temporal Bone Microanatomy
AbstractTemporal bone microanatomy is a  common source of consternation for radiologists. Serpentine foramina, branching cranial nerves, and bony canals containing often clinically relevant but often miniscule arterial branches may all cause confusion, even among radiologists familiar with temporal bone imaging. In some cases, the tinies t structures may be occult or poorly visualized, even on thin-slice computed tomography (CT) images. Consequently, such structures are often either ignored or mistaken for pathologic entities. Yet even the smallest temporal bone structures have significant anatomic and pathologic impo...
Source: Klinische Neuroradiologie - December 5, 2019 Category: Radiology Source Type: research

Angiographic Baseline Proximal Thrombus Appearance of M1/M2 Occlusions in Mechanical Thrombectomy
ConclusionBaseline cut off thrombus appearance predicts a  higher number of thrombectomy maneuvers. In day to day practice this may prepare the neurointerventionalist for a more challenging endovascular procedure ahead. Stroke etiology, clinical outcomes and thrombus-specific characteristics did not show any associations with the thrombus appearance. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - December 5, 2019 Category: Radiology Source Type: research

Flow Diversion for Treatment of Acutely Ruptured Intracranial Aneurysms
ConclusionFlow diversion is an attractive alternative strategy for management of acutely ruptured aneurysms with high rates of delayed complete occlusion and acceptable complication rates. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - November 4, 2019 Category: Radiology Source Type: research

Direct Admission vs. Secondary Transfer to a  Comprehensive Stroke Center for Thrombectomy
This study aimed at comparing short-term clinical outcome after thrombectomy in patients directly admitted (DA) to a  comprehensive stroke center with patients secondarily transferred (ST) from a primary stroke center.MethodsIn a  prospective regional stroke registry, all stroke patients with a premorbid modified Rankin scale (mRS) score 0–2 who were admitted within 24 h after stroke onset and treated with thrombectomy between 2014 and 2017 were retrospectively analyzed. Patients with DA and ST were compared regarding t he proportion of good outcome (discharge mRS 0–2), median discharge mR...
Source: Klinische Neuroradiologie - October 11, 2019 Category: Radiology Source Type: research

CNS Infections in Immunoincompetent Patients
AbstractIn patients with immunodeficiency the pathogen spectrum of central nervous system (CNS) infections is broader and different from that of immunocompetent patients. Numerous opportunistic infections are characterized by a high prevalence of viral, bacterial and parasitic pathogens, and depend on the type of impaired immune defense, for example impaired T ‑cell or monocyte function, monoclonal antibody treatment, and impaired granulocyte function. Neuroradiological features as well as laboratory findings are often different and versatile in comparison to immunocompetent individuals and pathognomonic imaging findings...
Source: Klinische Neuroradiologie - September 19, 2019 Category: Radiology Source Type: research

Merged Volume Rendered Flat-panel Computed Tomography for Postoperative Cochlear Implant Assessment
AbstractPurposeEvaluation of a  new postprocessing method for postoperative control of cochlear implants (CI) based on a single flat detector computed tomography (FD-CT) run and volume rendering of 3D models of the inner ear.MethodsThe FD-CT datasets of CIs were selected and postprocessed to generate both standard multiplanar reconstructions (MPR) and merged volume-rendered 3D datasets (MRD) of the CIs. The MRDs consisted of two different reconstructions (bone/implant) that are automatically layered to avoid manual coregistration inaccuracy. Corresponding datasets were evaluated in consensus reading in terms of q...
Source: Klinische Neuroradiologie - September 5, 2019 Category: Radiology Source Type: research

Carotid Artery Enlargement Causing Glossopharyngeal Neuralgia Successfully Treated with Stenting
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - August 23, 2019 Category: Radiology Source Type: research

Associations Between Diffusion Dynamics and Functional Outcome in Acute and Early Subacute Ischemic Stroke
AbstractPurposeThe current study aimed to investigate the associations between diffusion dynamics of ischemic lesions and clinical functional outcome of acute and early subacute stroke.Material and MethodsA total of 80 patients with first ever infarcts in the territory of the middle cerebral artery underwent multi-b-values diffusion-weighted imaging and diffusion kurtosis imaging. Multiple diffusion parameters were generated in postprocessing using different diffusion models. Long-term functional outcome was evaluated with modified Rankin scale (mRS) at 6 months post-stroke. Good functional outcome was defined as mRS score...
Source: Klinische Neuroradiologie - August 9, 2019 Category: Radiology Source Type: research

Preliminary Experience with Cangrelor for Endovascular Treatment of Challenging Intracranial Aneurysms
ConclusionCangrelor is a  new antiplatelet therapy with a P2Y12 inhibiting effect, with a rapid onset and offset of action, owing to its short half-life. This cases series presents a pilot experience with promising results in terms of antiplatelet management for challenging intracranial aneurysms treated by stent assist ed coiling or flow-diverter stents. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - July 15, 2019 Category: Radiology Source Type: research

Correction to: Accuracy and Reliability of Multiphase CTA Perfusion for Identifying Ischemic Core
Correction to:Clin Neuroradiol 2018https://doi.org/10.1007/s00062-018-0717-xUnfortunately, the author list of the original version of this article contains a  mistake. The middle name of the author “Rani Gupta Sah” was erroneously tagged as part of the surname in the article’s metadata.This mistake (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - June 3, 2019 Category: Radiology Source Type: research

Freiburg Neuropathology Case Conference: a  Hemorrhagic Intraspinal Tumor Extending from L3 to S1
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - May 22, 2019 Category: Radiology Source Type: research

The ReWiSed CARe Technique
ConclusionEndovascular treatment using ReWiSed CARe is safe, fast and efficient in TO patients with underlying atherosclerotic lesion of the extracranial ICA. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - May 22, 2019 Category: Radiology Source Type: research

Magnetic Resonance Imaging of the Brain Using Compressed Sensing  – Quality Assessment in Daily Clinical Routine
ConclusionThe use of CS saves considerable imaging time while allowing to increase spatial resolution in routine clinical brain MRI without loss in image quality. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - May 16, 2019 Category: Radiology Source Type: research

Treatment Outcomes of Cavernous Sinus Dural Arteriovenous Fistulas: Comparison of Radiosurgery and Endovascular Embolisation
This study compared the prognostic factors and treatment effectiveness of GKRS and EVT for different CSDAVF types.MethodsThe charts of 200 patients undergoing GKRS and 105 patients undergoing EVT were reviewed for data on symptoms (e.g. orbital, cavernous, ocular, and cerebral). The CSDAVFs were classified into proliferative, restrictive, and late restrictive types. The prognostic factors for complete obliteration (CO) were evaluated in both the GKRS and EVT groups and the latent period to CO was measured. For statistical analysis χ2-tests were used to compare final CO rates for EVT and GKRS across the three CSDAVF typ...
Source: Klinische Neuroradiologie - May 16, 2019 Category: Radiology Source Type: research

Transfemoral Approach for Intraoperative Angiography in the Prone or Three-quarter Prone Position
ConclusionThree key steps in setting-up a  prone IOA procedure for intracranial AVM/AVF surgery are proposed: (1) utilize an extended femoral sheath approach, (2) establish a localization landmark with an aneurysm clip and (3) avoid possible image interference from the non-radiolucent component of the head clamp. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - April 29, 2019 Category: Radiology Source Type: research

Angiographic Patterns and Outcomes Achieved by Proximal Balloon Occlusion in Symptomatic Carotid Artery Stenosis Stenting
ConclusionThe SFB technique enables fast and safe procedures in CAS. A  favorable angiographic pattern after proximal balloon inflation was observed in 74.2% of cases. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - March 7, 2019 Category: Radiology Source Type: research

Information
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - February 11, 2019 Category: Radiology Source Type: research

Regional Metabolite Concentrations in Aging Human Brain: Comparison of Short-TE Whole Brain MR Spectroscopic Imaging and Single Voxel Spectroscopy at  3T
ConclusionThe wbMRSI could be used to estimate metabolites in vivo and in vitro with the same reliability as using SVS, with the main advantage being the ability to determine metabolite concentrations in multiple brain structure simultaneously in vivo. It is expected to be widely used in clinical diagnostics and neuroscience. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - January 18, 2019 Category: Radiology Source Type: research

Magnetic Resonance Imaging Characteristics of Retinal Vasculopathy with Cerebral Leukoencephalopathy and Systemic Manifestations
ConclusionPeriventricular patchy white matter lesions in the frontal lobes as well as rim-enhancing lesions with prolonged diffusion restriction and long-lasting contrast enhancement are characteristic imaging findings in RCVL-S and can be helpful in the differential diagnosis. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - January 9, 2019 Category: Radiology Source Type: research

Dural Arteriovenous Fistula Presenting as Tentorial Subdural Hemorrhage
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - December 18, 2018 Category: Radiology Source Type: research

Teaching Neuroimages: Inflammatory CAA
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - December 12, 2018 Category: Radiology Source Type: research

Acute Occlusion of the Distal Internal Carotid Artery
ConclusionsThe proposed classification reproduces more precisely the complexity and heterogeneity of this pathology, being useful in the diagnosis and treatment of these patients. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - November 13, 2018 Category: Radiology Source Type: research

Response to Letter to the Editor “Preoperative Digital Subtraction Angiography in Incidental Unruptured Intracranial Aneurysms”
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - August 13, 2018 Category: Radiology Source Type: research

Importance of the First Coil in the Embolization of Intracranial Aneurysms
ConclusionThe 1st VPD and 1st LD were associated with aneurysmal recanalization after embolization. These factors provide a  helpful index for coil programming. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - July 25, 2018 Category: Radiology Source Type: research

Mechanical Thrombectomy —A Brief Review of a Revolutionary new Treatment for Thromboembolic Stroke
AbstractThe recent success of endovascular stroke treatment has heralded a  new era in the management of acute ischemic stroke (AIS) with significantly improved outcome for patients. A large number of patients may be amenable to this new treatment and as the evidence expands the number of patients eligible for mechanical thrombectomy continues to increase. Recent evidenc e suggests that the time window for treatment can be extended up to 24 h after symptom onset for patients with anterior circulation strokes; however, many clinicians and medical professionals may not be aware of these recent changes and it is i...
Source: Klinische Neuroradiologie - May 9, 2018 Category: Radiology Source Type: research

The Medical Informatics Consortia: How Does Neuroradiology Benefit?
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - May 9, 2018 Category: Radiology Source Type: research

Preoperative Digital Subtraction Angiography in Incidental Unruptured Intracranial Aneurysms
This study aimed to evaluate whether the evaluation of all vessels beyond the aneurysm-harboring artery is really necessary.Material and methodsPatients with an UIA that was detected on MRA (TOF/ceMRA) were prospectively included. All patients underwent a  four-vessel DSA (including 3D-DSA) and two experienced neuroradiologists independently analyzed the MRI sequences before DSA. The number of aneurysms, size and anatomic localization were documented and correlated with the angiographic findings.ResultsThe DSA revealed a  total of 134 aneurysms in 106 patients. Overall sensitivity and negative predictive value of...
Source: Klinische Neuroradiologie - April 24, 2018 Category: Radiology Source Type: research

Cervical Spine Prospective Feasibility Study
ConclusionsDynamic DTI of the cervical spine is feasible and ADC increased in the patient group in extension. This finding may open a previously unexplored avenue to attempt an earlier identification of myelopathy. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - April 18, 2018 Category: Radiology Source Type: research

Posterior Circulation Occlusions May Be Associated with Distal Emboli During Thrombectomy
ConclusionPosterior circulation occlusions were significantly associated with distal emboli during thrombectomy, possibly due to the lack of flow arrest during such procedures. New techniques and devices should be developed to protect against embolic complications during posterior circulation stroke thrombectomy. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - March 22, 2018 Category: Radiology Source Type: research

Treatment of Unruptured, Saccular, Anterior Choroidal Artery Aneurysms with Flow Diversion
ConclusionFlow diversion can be used to successfully treat aneurysms of the AChoA. The treatment carries a  high rate of technical and radiological success with a good safety profile. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - March 7, 2018 Category: Radiology Source Type: research

Diagnosing Neoplastic Hematoma: Role of MR Perfusion
ConclusionIn our small series, the combination of peripheral linear enhancement and increased CBF and CBV showed 100% sensitivity, specificity, PPV and NPV for diagnosing a  neoplastic hematoma. These findings need to be validated in a larger study. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - February 7, 2018 Category: Radiology Source Type: research

Various Cranial and Orbital Imaging Findings in Pediatric Abusive and Non-abusive Head trauma, and Relation to Outcomes
ConclusionNeuroimaging findings can be helpful in discriminating these two conditions on presentation, as well as in helping solidify the suspicion of AHT. Regarding eventual outcome in AHT, the most important predictor is clearly HII. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - January 23, 2018 Category: Radiology Source Type: research