Hemodynamic Impairments of Evaluating Symptomatic Intracranial Atherosclerotic Stenosis using Quantitative Flow Ratio on Digital Subtraction Angiography
ConclusionThe μQFR based on DSA images can be used as an indicator to assess the functional status of the lesion in patients with ICAS. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - March 15, 2024 Category: Radiology Source Type: research

Safety and Efficacy of LVIS Jr Stent-assisted Coiling of Intracranial Aneurysms in Small-diameter Parent Arteries
ConclusionThe LVIS Jr SAC is effective for managing IAs in small-diameter parent arteries. An aneurysm size>  10.0 mm, parent artery mean diameter<  2.0 mm, and incomplete stent apposition at the aneurysm neck are possible risk factors for incomplete aneurysm occlusion. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - March 7, 2024 Category: Radiology Source Type: research

Intensive Blood Pressure Control After Endovascular Thrombectomy for Acute Ischemic Stroke: a  Systematic Review and Meta-Analysis
ConclusionsAn intensive BP target after EVT is associated with worse neurological recovery and significantly decreased rates of functional independence and independent ambulation compared to the standard BP target. Therefore, the intensive BP target should be avoided after EVT for acute ischemic stroke. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - March 7, 2024 Category: Radiology Source Type: research

Neuroimaging Abnormalities in Patients with Subacute Sclerosing Panencephalitis
ConclusionParieto-occipital White matter hyperintensity (WMH) is the most prevalent and sensitive neuroimaging finding for the diagnosis of SSPE. Despite interferon treatment, cerebral atrophy progressed in both aggressive and fulminant SSPE. Increasing disease duration is an independent predictor of cerebral atrophy. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - March 7, 2024 Category: Radiology Source Type: research

Haberland Syndrome (Encephalocraniocutaneous Lipomatosis) with Development of Diffuse Leptomeningeal Glioneural Tumor (DL-GNT) during Adolescence
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - February 14, 2024 Category: Radiology Source Type: research

Retrograde Parent Artery Occlusion for Ruptured Intracranial Vertebral Artery Dissecting Aneurysms Involving the Posterior Inferior Cerebellar Artery: The “Breakwater” Technique
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - February 2, 2024 Category: Radiology Source Type: research

MicroCT and Histological Analysis of Clot Composition in Acute Ischemic Stroke
ConclusionMicroCT can be used to build models that predict AIS clot composition from routine CT parameters and help us to better understand radiomic signatures associated with clot composition and first pass outcomes. In future work, such observations can be used to better infer clot composition and inform thrombectomy prognostics from pretreatment CTs. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - January 31, 2024 Category: Radiology Source Type: research

Quantitative Magnetic Resonance Imaging for Neurodevelopmental Outcome Prediction in Neonates Born Extremely Premature —An Exploratory Study
ConclusionThere are relationships between relaxometry ‑/DTI-based metrics determined by neuroimaging near term and neurodevelopmental outcomes collected at one year of age. Both modalities bear prognostic potential for the prediction of cognitive and motor outcomes. Thus, quantitative MRI at term-equivalent ages represents a promising approach with which to estimate neurologic development in extremely preterm infants. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - January 30, 2024 Category: Radiology Source Type: research

Complemental Value of Microstructural and Macrostructural MRI in the Discrimination of Neurodegenerative Parkinson Syndromes
ConclusionWe were able to demonstrate that (1) MRI parameters that approximate the microstructure provided substantial added value over conventional macrostructural imaging, (2) multicompartmental biophysically motivated models performed better than the single compartmental DTI and (3) combining macrostructural and microstructural information classified NPS and HC with satisfactory performance, thus suggesting a  complementary value of both approaches. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - January 30, 2024 Category: Radiology Source Type: research

Detection of Spinal Cord Multiple Sclerosis Lesions Using a 3D-PSIR Sequence at 1.5  T
ConclusionEvaluation of the spinal cord with a  3D PSIR sequence at a magnetic field strength of 1.5 T is feasible with a high sensitivity for the detection of spinal MS lesions for the cervical as well as the thoracic segments. In combination with other pulse sequences it might become a valuable addition in an advanced imaging protocol. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - January 30, 2024 Category: Radiology Source Type: research

Challenges and Potential of Artificial Intelligence in Neuroradiology
ConclusionTranslating AI methods from the research to the clinical domain is complicated by challenges related to model design and validation studies, medical product regulations, and healthcare providers ’ reservations regarding AI’s efficacy and affordability. However, each of these limitations is also an opportunity for high-impact research that will help to accelerate the clinical adoption of state-of-the-art medical AI. In all cases, establishing and adhering to appropriate reporting standar ds is an important responsibility that is shared by all of the parties involved in the life cycle of a prospective AI softw...
Source: Klinische Neuroradiologie - January 29, 2024 Category: Radiology Source Type: research

Here to Stay: The Journey of “Junge Neuroradiologie” Has Only Just Begun
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - January 29, 2024 Category: Radiology Source Type: research

Severe Complications After Ozone Therapy-related Stroke
(Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - January 25, 2024 Category: Radiology Source Type: research

Multiparametric Analysis Combining DSC-MR Perfusion and [18F]FET-PET is Superior to a  Single Parameter Approach for Differentiation of Progressive Glioma from Radiation Necrosis
ConclusionA  multiparametric MRI-PWI and [18F]FET-PET model consisting of TBRmean, rCBVmean and PWI rTTP significantly outperformed the use of rTBRmean alone, which was the best single parameter approach. Secondarily, we firstly report the potential usefulness of PWI rTTP for discrimination of PD from RN in patients with glioma; however, for validation of our findings the prospective studies with larger patient samples are necessary. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - December 29, 2023 Category: Radiology Source Type: research

Efficacy and Safety of Dual Antiplatelet Therapy with the Routine Use of Prasugrel for Flow Diversion of Cerebral Unruptured Aneurysms
ConclusionsDual antiplatelet therapy comprising routine use of prasugrel and aspirin for flow diverter-implanted patients possibly contributed to a  low rate of thromboembolic complications and low risk of hemorrhagic complications. (Source: Klinische Neuroradiologie)
Source: Klinische Neuroradiologie - October 17, 2023 Category: Radiology Source Type: research