The health impacts of preventive cardiovascular medication reduction on older populations: protocol for a systematic review and meta-analysis
DiscussionThe study will be a comprehensive review on all published articles identified using our search strategy on the safety and efficacy of cardioprotective medication reduction in the older population. The findings will be crucial to inform clinicians on potential health outcomes of reducing cardiovascular medication in the elderly.Systematic review registrationPROSPERO CRD42020208223 (Source: Systematic Reviews)
Source: Systematic Reviews - June 24, 2021 Category: International Medicine & Public Health Source Type: research

Low birth weight as a predictor of adverse health outcomes during adulthood in twins: a systematic review and meta-analysis
ConclusionsThe odds of low birth weight were found to be high in both asthma and cerebral palsy. There are not enough studies of similar nature (study types, similar body systems) to ensure a meaningful meta-analysis. We recommend that future research considers following up on twins to obtain data about adverse health outcomes during their adult lives. (Source: Systematic Reviews)
Source: Systematic Reviews - June 24, 2021 Category: International Medicine & Public Health Source Type: research

Peer-to-peer health promotion interventions among African American men: a scoping review protocol
DiscussionResults will have implications for the design, implementation, and evaluation of health promotion interventions among African American men.Systematic review registrationPROSPERO CRD42020198664 (Source: Systematic Reviews)
Source: Systematic Reviews - June 22, 2021 Category: International Medicine & Public Health Source Type: research

Health outcomes of sexual and gender minorities after cancer: a systematic review
ConclusionsA growing literature describes the patient-reported health outcomes of SGM people with a history of cancer. This study summarizes important between-group differences among SGM and heterosexual, cisgender counterparts that are critical for clinicians to consider when providing care.Implications for cancer survivorsSexual orientation and gender identity are relevant to cancer survivors ’ health outcomes. Subgroups of SGM people have differential experiences and outcomes related to cancer and its impacts. (Source: Systematic Reviews)
Source: Systematic Reviews - June 21, 2021 Category: International Medicine & Public Health Source Type: research

The lived experience of people with obesity: study protocol for a systematic review and synthesis of qualitative studies
The objective of SOPHIA is to optimise future obesity treatment and stimulate a new narrative, understanding and vocabulary around obesity as a set of complex and chronic diseases. The findings will also be useful to health care providers and policy makers who seek to understand the experience of those with obesity.Systematic review registrationPROSPEROCRD42020214560. (Source: Systematic Reviews)
Source: Systematic Reviews - June 21, 2021 Category: International Medicine & Public Health Source Type: research

Digital technologies to support people living with dementia in the care home setting to engage in meaningful occupations: protocol for a scoping review
DiscussionMapping the range of technologies to support PLWD to engage in meaningful occupations will identify gaps in research. The systematic search will include a diverse range of technologies such as software to enhance care planning, tablets devices, smartphones, communication robots and social media platforms, rather than focussing on a specific design or interface. This will enable comparison between mechanisms of action, barriers and facilitators to implementation which will be useful for future research and intervention design.Trial registrationOpen Science Frameworkhttps://doi.org/10.17605/OSF.IO/7UDM2 (Source: Systematic Reviews)
Source: Systematic Reviews - June 21, 2021 Category: International Medicine & Public Health Source Type: research

Mapping evidence on management of cervical cancer in sub-Saharan Africa: scoping review protocol
DiscussionCervical cancer can become a disease of the past with a proper control strategy in place. It is therefore imperative to map available evidence on the management of cervical cancer to inform policy and advocacy action. More knowledge on the status quo will guide policymakers in ensuring cancer management guiding policies are formulated/updated/revised accordingly.Systematic review registrationNot registered with PROSPERO (not needed).Protocol and registrationThis scoping review was not registered. (Source: Systematic Reviews)
Source: Systematic Reviews - June 21, 2021 Category: International Medicine & Public Health Source Type: research

Exploring the comorbidity of musculoskeletal and personality disorders among adults: a scoping review protocol
DiscussionInformation will be synthesised to inform a discussion of what is known regarding associations between PD and MSDs, and the burden associated with their comorbidity in different contexts, with future research directions proposed.Systematic review registrationThis protocol is registered in Open Science Framework Registries (https://osf.io/mxbr2/). (Source: Systematic Reviews)
Source: Systematic Reviews - June 21, 2021 Category: International Medicine & Public Health Source Type: research

Improved couple satisfaction and communication with marriage and relationship programs: are there gender differences? —a systematic review and meta-analysis
ConclusionDue to the high effect of the therapy programs on CRS and enhancement program on CRC in the current meta-analysis, the priority of their utilizations in interventions, especially by psychologists and mental health professionals, should be emphasized. Therefore, mental health planning in communities to develop MRP and care for couples ’ health should be given special attention to men’s health. Due to the high heterogeneity of the results and with scanty literature in this specific domain, we are uncertain about their actual effect. However, well-designed RCTs with a larger sample size would be benefici...
Source: Systematic Reviews - June 21, 2021 Category: International Medicine & Public Health Source Type: research

A systematic review on the effectiveness of implementation strategies to postpone elective caesarean sections to ≥ 39 + (0–6) weeks of gestation
AbstractBackgroundCaesarean sections often have no urgent indication and are electively planned. Research showed that elective caesarean section should not be performed until 39 + (0 –6) weeks of gestation to ensure best neonatal and maternal health if there are no contraindications. This was recommended by various guidelines published in the last two decades. With this systematic review, we are looking for implementation strategies trying to implement these recommendations to reduce elective caesarean section before 39 + (0–6) weeks of gestation.MethodsWe performed a systematic literature search in MEDLINE, EM...
Source: Systematic Reviews - June 14, 2021 Category: International Medicine & Public Health Source Type: research

Red blood cell transfusion in animal models of acute brain injuries: a systematic review protocol
DiscussionOur study is aligned with the efforts to better understand the level of evidence on the impact of red blood cell transfusion strategies from preclinical studies in animal models of acute brain injury and the potential translation of information from the preclinical to the clinical research field.Systematic review registrationPROSPEROCRD42018086662. (Source: Systematic Reviews)
Source: Systematic Reviews - June 14, 2021 Category: International Medicine & Public Health Source Type: research

Dealing with predatory journal articles captured in systematic reviews
ConclusionEncountering eligible articles published in presumed predatory journals when conducting a review is an increasingly common threat. Developing appropriate methods to account for eligible research published in predatory journals is needed to decrease the potential negative impact of predatory journals on healthcare. (Source: Systematic Reviews)
Source: Systematic Reviews - June 11, 2021 Category: International Medicine & Public Health Source Type: research

Duloxetine versus ‘active’ placebo, placebo or no intervention for major depressive disorder; a protocol for a systematic review of randomised clinical trials with meta-analysis and trial sequential analysis
DiscussionNo former systematic review has systematically assessed the beneficial and harmful effects of duloxetine taking into account both the risks of random errors and the risks of systematic errors. Our review will help clinicians weigh the benefits of prescribing duloxetine against its adverse effects and make informed decisions.Systematic review registrationPROSPERO 2016CRD42016053931 (Source: Systematic Reviews)
Source: Systematic Reviews - June 9, 2021 Category: International Medicine & Public Health Source Type: research

Management of patellofemoral joint osteoarthritis using biomechanical device therapy: a systematic review with meta-analysis
ConclusionThere is some good quality evidence that a combined physiotherapy approach significantly reduces short-term pain in those with PFJOA. Long-term effects of all interventions are still unknown, which indicates the need for further research to determine the longer term impact of all biomechanical devices on outcomes in symptomatic PFJOA. (Source: Systematic Reviews)
Source: Systematic Reviews - June 9, 2021 Category: International Medicine & Public Health Source Type: research

Post-abortion family planning use, method preference, and its determinant factors in Eastern Africa: a systematic review and meta-analysis
ConclusionsThis study revealed that the marital status of the women, multiparity, having a history of abortion, getting counselling on post-abortion family planning, and ever used contraceptives were found to be significantly associated with post-abortion family planning utilization. (Source: Systematic Reviews)
Source: Systematic Reviews - June 9, 2021 Category: International Medicine & Public Health Source Type: research

The influence of single nucleotide polymorphisms of NOD2 or CD14 on the risk of Mycobacterium tuberculosis diseases: a systematic review
ConclusionsTheCD14 rs2569190 and rs2569191 polymorphisms may influence riskof Mtb diseases depending on the allele. Furthermore, there is significant association betweenNOD2 SNPs rs1861759 and rs7194886 and augmented riskof Mtb diseases, especially in persons of Chinese ethnicity. The referred polymorphisms ofCD14 andNOD2 genes likely play an important role in riskof Mtb diseases and pathology and may be affected by ethnicity.Systematic review registrationCRD42020186523 (Source: Systematic Reviews)
Source: Systematic Reviews - June 9, 2021 Category: International Medicine & Public Health Source Type: research

Healthcare provider characteristics that influence the implementation of individual-level patient-centered outcome measure (PROM) and patient-reported experience measure (PREM) data across practice settings: a protocol for a mixed methods systematic review with a narrative synthesis
DiscussionData from PROMs and PREMs are critical to adopt a person-centered approach to healthcare. Findings from this review will guide subsequent phases of a larger project that includes interviews and a consensus-building forum with end users to create guidelines for implementing PROMs and PREMs at the point of care.Systematic review registrationPROSPEROCRD42020182904. (Source: Systematic Reviews)
Source: Systematic Reviews - June 9, 2021 Category: International Medicine & Public Health Source Type: research

A survey of methodologies on causal inference methods in meta-analyses of randomized controlled trials
ConclusionsWe undertook a review of methodologies on causal inference methods in meta-analyses. Although all identified methodologies provide valid causal estimates, there are limitations in the assumptions regarding the data generation process and sampling of the potential RCTs to be included in the meta-analysis which pose challenges to the interpretation and scientific relevance of the identified causal effects. Despite both causal inference and meta-analysis being extensively studied in the literature, limited effort exists of combining those two frameworks. (Source: Systematic Reviews)
Source: Systematic Reviews - June 9, 2021 Category: International Medicine & Public Health Source Type: research

Access to and experience of education for children and adolescents with cancer: a scoping review protocol
DiscussionThis is a timely examination given the increased incidence of childhood cancer, more intensive treatment regimens and improved survival rates for childhood cancer. The inclusion of a substantive consultation exercise with families and professionals will provide an important opportunity to examine the scoping review outputs. Findings will assist the childhood cancer community in developing a comprehensive evidence-based understanding of a significant associated bio-psychosocial impact of cancer diagnosis and treatment and will form the first step towards developing effective interventions and policies to mitigate ...
Source: Systematic Reviews - June 7, 2021 Category: International Medicine & Public Health Source Type: research

Correction to: Community mobilisation approaches to preventing and reducing adolescent multiple risk behaviour: a realist review protocol
(Source: Systematic Reviews)
Source: Systematic Reviews - June 7, 2021 Category: International Medicine & Public Health Source Type: research

Non-pharmacological sleep interventions for pediatric cancer patients and survivors: a systematic review protocol
The objective of the review is to evaluate the effect of non-pharmacological sleep interventions on sleep quality in pediatric cancer patients and survivors.MethodsThe review will consider studies that include children and adolescents between 0 and 18  years diagnosed with cancer or who have a history of cancer who have non-respiratory sleep disturbance. We will include experimental and quasi-experimental studies evaluating non-pharmacological interventions such as psychological interventions, technical/device interventions, interventions targe ting physical activity, and complementary and alternative medicine inter...
Source: Systematic Reviews - June 4, 2021 Category: International Medicine & Public Health Source Type: research

Factors leading to effective social participation promotion interventions for people with intellectual disability: a protocol for a systematic review
This study aims to identify and organize the factors associated with interventions that increase the social participation of people with intellectual disabilities and to provide a set of best of practices for future interventions.Methods/designThe databases Web of Science, Scopus, LILACS, and PubMed will be searched for articles from January 2004 onwards; grey literature search will be identified through searching additional databases (such as Google Scholar and EBSCO databases). Randomized controlled trials, nonrandomized controlled trials, and controlled pre –post studies will be included. Noncontrolled pre–p...
Source: Systematic Reviews - June 4, 2021 Category: International Medicine & Public Health Source Type: research

Measurement properties of patient-reported outcome measures (PROMs) in patients with hyperhidrosis: protocol for a systematic review
DiscussionIn our systematic review, we aim to provide a comprehensive description of the quality of all existing PROMs for patients with hyperhidrosis. The assessment of measurement properties, interpretability, and feasibility will serve as a guidance regarding the selection of PROMs for future clinical hyperhidrosis trials.Systematic review registrationPROSPERO CRD42020170247 (Source: Systematic Reviews)
Source: Systematic Reviews - June 2, 2021 Category: International Medicine & Public Health Source Type: research

The impacts of health systems financing fragmentation in low- and middle-income countries: a systematic review protocol
The objective of the systematic review described in this protocol will be to evaluate and synthesize the evidence concerning the impacts of health systems financing fragmentation in LMICs.MethodsLiterature searches will be conducted in multiple electronic databases, from their inception onwards, including MEDLINE, EMBASE, LILACS, CINAHL, Scopus, ScienceDirect, Scielo, Cochrane Library, EconLit, and JSTOR. Gray literature will be also targeted through searching OpenSIGLE, Google Scholar, and institutional websites (e.g., HMIC, The World Bank, WHO, PAHO, OECD). The search strings will include keywords related to LMICs, healt...
Source: Systematic Reviews - June 2, 2021 Category: International Medicine & Public Health Source Type: research

Interventions directed at men for preventing intimate partner violence: a systematic review protocol
The objective of this systematic review is to identify interventions specifically directed at  males , as the perpetrators of violence against women, that have proven to be effective in preventing or reducing intimate partner violence.MethodsThe following electronic databases will be used to search for peer-reviewed studies: MEDLINE (OVID), Embase (OVID), PsycInfo (OVID), CINAHL (EBSCO), Global Health (EBSCO), Gender Watch (ProQuest), Web of Science (Web of Knowledge), PROSPERO, Cochrane Central Register of Controlled Trials Database (Ovid) and SCOPUS. We will include randomized control trials, non-randomized studies ...
Source: Systematic Reviews - June 1, 2021 Category: International Medicine & Public Health Source Type: research

Developing a topic-based repository of clinical trial individual patient data: experiences and lessons learned from a pilot project
ConclusionsWe would recommend that researchers conducting IPD meta-analysis should consider discussing the option to transfer the curated IPD datasets to a repository at the end of the initial meta-analysis and this should be recognised within the data sharing agreements made with the original data contributors. (Source: Systematic Reviews)
Source: Systematic Reviews - June 1, 2021 Category: International Medicine & Public Health Source Type: research

Molecular mechanisms of Zika virus teratogenesis from animal studies: a systematic review protocol
DiscussionWith the proposed systematic review, we expect to present results about the methodological quality of the published studies with animal models that investigated the molecular mechanisms involved in the teratogenic effect of ZIKV, as well as to show the studies with greater reliability.Systematic review registrationPROSPEROCRD42019157316 (Source: Systematic Reviews)
Source: Systematic Reviews - May 29, 2021 Category: International Medicine & Public Health Source Type: research

Anti-epileptic drug exposure during pregnancy and neonatal birth weight outcomes: protocol for a systematic review and meta-analysis
DiscussionThe results from this review could improve clinicians ’ prescribing decisions by highlighting the safest AEDs for women who are pregnant or planning to conceive based on the evidence currently available.Systematic review registrationPROSPERO CRD42020192713 (Source: Systematic Reviews)
Source: Systematic Reviews - May 29, 2021 Category: International Medicine & Public Health Source Type: research

Evidence on collaboration of traditional and biomedical practitioners in the management of antimicrobial resistance in sub-Saharan Africa over 15 years: a systematic review protocol
DiscussionThis review anticipates uncovering pertinent publications reporting the evidence of collaboration between traditional health practitioners and biomedically trained healthcare professionals to reduce antimicrobial resistance in sub-Saharan Africa. The sum-up of evidence acquired from the included studies will help guide future research. The result of the study will be print and electronically exposed.Systematic review registrationPROSPERO,CRD42017072952 (Source: Systematic Reviews)
Source: Systematic Reviews - May 28, 2021 Category: International Medicine & Public Health Source Type: research

A systematic and meta-analysis review on the diagnostic accuracy of antibodies in the serological diagnosis of COVID-19
ConclusionsWe report that IgG-IgM based ELISA tests have the best overall diagnostic test accuracy. Moreover, irrespective of the method, a combined IgG/IgM test seems to be a better choice in terms of sensitivity than measuring either antibody type independently. Given the poor performances of the current LFIA devices, there is a need for more research on the development of highly sensitivity and specific POC LFIA that are adequate for most individual patient applications and attractive for large sero-prevalence studies.Systematic review registrationPROSPEROCRD42020179112 (Source: Systematic Reviews)
Source: Systematic Reviews - May 26, 2021 Category: International Medicine & Public Health Source Type: research

Text mining to support abstract screening for knowledge syntheses: a semi-automated workflow
ConclusionThe workflow was a sensitive, precise, and efficient alternative to the recommended practice of screening abstracts with 2 reviewers. All eligible studies were identified in the first case, while 6 studies (1.5%) were missed in the second that would likely not impact the review ’s conclusions. We have described the workflow in language accessible to reviewers with limited exposure to natural language processing and machine learning, and have made the code available to reviewers. (Source: Systematic Reviews)
Source: Systematic Reviews - May 26, 2021 Category: International Medicine & Public Health Source Type: research

Dzherelo (Immunoxel) as adjunctive therapy to standard antituberculosis treatment in patients with pulmonary tuberculosis: a systematic review and meta-analysis of clinical trials
ConclusionCurrent evidence indicates that the use of Immunoxel as an adjunctive treatment in patients with pulmonary tuberculosis has the potential to enhance the efficacy of antituberculosis treatment. However, well-designed, conducted and adequately powered clinical trials are needed to establish the effectiveness of this adjunctive treatment.Systematic review registrationPROSPERO registration number:CRD42019127823 (Source: Systematic Reviews)
Source: Systematic Reviews - May 26, 2021 Category: International Medicine & Public Health Source Type: research

Beneficial and harmful effects of antidepressants versus placebo, ‘active placebo’, or no intervention for adults with major depressive disorder: a protocol for a systematic review of published and unpublished data with meta-analyses and trial sequential analyses
DiscussionAs antidepressants are commonly used to treat major depressive disorder in adults, a systematic review evaluating their beneficial and harmful effects is urgently needed. This review will inform best practice in treatment and clinical research of this highly prevalent and burdensome disorder.Systematic review registrationPROSPEROCRD42020220279 (Source: Systematic Reviews)
Source: Systematic Reviews - May 25, 2021 Category: International Medicine & Public Health Source Type: research

Mapping evidence on standards and quality of care for older persons in long-term care facilities: a scoping review protocol
This study, therefore, will aim to systematically map literature and describe the evidence on standards and the quality of health care for older persons living in long-term care facilities (LTCFs).MethodsA scoping review will be conducted using Arksey and O ’Malley’s framework and recommendations set out by Levac and colleagues. PubMed, CINAHL, Health Sources, PsycInfo, Web of Science, Scopus, and Google Scholar will be searched for relevant published studies/sources of evidence up to the last search date. The search will be conducted using keyword s, and Boolean terms, and Medical Subject Headings/Subject Head...
Source: Systematic Reviews - May 22, 2021 Category: International Medicine & Public Health Source Type: research

The effects of meditation on length of telomeres in healthy individuals: a systematic review
ConclusionThe effect of meditation on TL per se is still unclear. Strictly designed and well-reported RCTs with larger sample sizes are required to provide evidence of higher quality.Systematic review registrationThe protocol of this review was registered with the International Prospective Register of Systematic Reviews (PROSPERO) database (registration number:CRD42020153977). (Source: Systematic Reviews)
Source: Systematic Reviews - May 21, 2021 Category: International Medicine & Public Health Source Type: research

Vaginal progesterone for prevention of preterm birth in asymptomatic high-risk women with a normal cervical length: a systematic review and meta-analysis protocol
AbstractBackgroundPreterm birth (PTB) is estimated to affect 14.9 million babies globally every year. Global rates of PTB continue to increase from 9.8 to 10.6% over a 15-year period from 2000 to 2014. Vaginal progesterone is commonly used by clinicians as a prevention strategy, with recent evidence affirming the benefit of vaginal (micronised) progesterone to prevent PTB in women with a shortened cervix (
Source: Systematic Reviews - May 21, 2021 Category: International Medicine & Public Health Source Type: research

Effectiveness of matching human leukocyte antigens (HLA) in corneal transplantation: a systematic review protocol
DiscussionMany studies have investigated the effectiveness of HLA matching for corneal transplantation. A systematic review is needed to collate and analyse this evidence. Findings of this systematic review may form the basis of evidence-based recommendations on pre-operative HLA typing and matching of corneal grafts for transplantation.Systematic review registrationPROSPERO referenceCRD42020198882 (Source: Systematic Reviews)
Source: Systematic Reviews - May 20, 2021 Category: International Medicine & Public Health Source Type: research

Prognostic models for knee osteoarthritis: a protocol for systematic review, critical appraisal, and meta-analysis
DiscussionOur systematic review will collate evidence from prognostic prediction models that can be used through the whole process of KOA. The review may identify models which are capable of allowing personalized preventative and therapeutic interventions to be precisely targeted at those individuals who are at the highest risk. To accomplish the prediction models to cross the translational gaps between an exploratory research method and a valued addition to precision medicine workflows, research recommendations relating to model development, validation, or impact assessment will be made.Systematic review registrationPROSP...
Source: Systematic Reviews - May 19, 2021 Category: International Medicine & Public Health Source Type: research

Prevalence and incidence of venous leg ulcers —a protocol for a systematic review
The objective of this protocol is to present a transparent process for how we plan to review the existing international literature on the prevalence and incidence of VLU as well as the characteristics of the population reported within these studies.MethodsAn exploratory search was performed using MEDLINE via PubMed and CINHAL via Ebsco to identify concepts, keywords, MeSH terms, and headings to identify study types looking at data of VLU prevalence and/or incidence and related patient characteristics. The findings of this exploratory search will determine the final search strategy. The titles and abstracts of the identifie...
Source: Systematic Reviews - May 12, 2021 Category: International Medicine & Public Health Source Type: research

Community mobilisation approaches to preventing and reducing adolescent multiple risk behaviour: a realist review protocol
The objective of this study is to understand ‘how, why, for whom and in what circumstances and time periods’ do community mobilisation interventions work to prevent and/or reduce adolescent multiple risk behaviour.MethodsThis is a protocol for a realist review. The review will use a six-stage iterative process, guided by the RAMESES framework. We will systematically search PubMed, MEDLINE, PsycINFO, Web of Science, CINAHL and Sociological Abstracts, from their inception to 2021. Studies will be screened for relevance to the programme theory and included based on a priori eligibility criteria including (1) repor...
Source: Systematic Reviews - May 12, 2021 Category: International Medicine & Public Health Source Type: research

The effect of preoperative stoma site marking on risk of stoma-related complications in patients with intestinal ostomy —protocol of a systematic review and meta-analysis
The objective of the systematic review will be to investigate if preoperative stoma site marking compared to no preoperative marking in patients undergoing intestinal stoma surgery reduces or prevents the rate of stoma-related complications.MethodsWe will include (cluster-) randomised controlled trials and cohort studies that involve patients with intestinal ostomies comparing preoperative stoma site marking to no preoperative marking and report at least one patient-relevant outcome. For study identification, we will systematically search MEDLINE/PubMed, EMBASE, CENTRAL and CINHAL as well as Google Scholar, trial registrie...
Source: Systematic Reviews - May 12, 2021 Category: International Medicine & Public Health Source Type: research

AGREEing on clinical practice guidelines for idiopathic steroid-sensitive nephrotic syndrome in children
ConclusionsThe methodological quality of the KDIGO CPG was superior, followed by JSPN and AAP CPGs with the relevant recommendations for use in practice.Systematic review registrationThe protocol was registered in the Center for Open Science (OSF) DOI: 10.17605/OSF.IO/6QTMD and in the International prospective register of systematic reviews PROSPERO 2020CRD42020197511. (Source: Systematic Reviews)
Source: Systematic Reviews - May 10, 2021 Category: International Medicine & Public Health Source Type: research

Non-invasive and minimally invasive glucose monitoring devices: a systematic review and meta-analysis on diagnostic accuracy of hypoglycaemia detection
ConclusionOverall, the present data suggest that minimally and non-invasive monitoring systems are not sufficiently accurate for detecting hypoglycaemia in routine use.Systematic review registrationPROSPERO 2018CRD42018104812 (Source: Systematic Reviews)
Source: Systematic Reviews - May 10, 2021 Category: International Medicine & Public Health Source Type: research

Deciphering the role of physical activity in stress management during a global pandemic in older adult populations: a systematic review protocol
DiscussionThis review will determine the effectiveness of various physical activity interventions for the treatment of psychological stress among the older adult population. This knowledge will help inform care aides, clinicians, family members, and older adults themselves of the most effective physical activity interventions in dealing with stress which is relevant to the ongoing pandemic.Systematic review registrationPROSPEROCRD42020192546 (Source: Systematic Reviews)
Source: Systematic Reviews - May 7, 2021 Category: International Medicine & Public Health Source Type: research

Impact of child development at primary school entry on adolescent health —protocol for a participatory systematic review
DiscussionThe review will elucidate how children ’s development at the age of starting school is related to subsequent health outcomes in contexts of socioeconomic inequality. This will inform ways to intervene to improve health and reduce health inequality in adolescents. The findings will generate knowledge of cross-sector relevance for health and education and promote inter-sectoral coherence in addressing health inequalities throughout childhood.Protocol RegistrationThis systematic review protocol has been registered with PROSPEROCRD42020210011. (Source: Systematic Reviews)
Source: Systematic Reviews - May 7, 2021 Category: International Medicine & Public Health Source Type: research

Illness perceptions of adults with eczematous skin diseases: a systematic mixed studies review
ConclusionPatients with eczematous skin diseases have complex illness representations regarding their disease. These representations interrelate with the coping behavior of patients. Therefore, medical professionals should consider them for counseling and treatment.Systematic review registrationPROSPERO 2018CRD42018109217. (Source: Systematic Reviews)
Source: Systematic Reviews - May 7, 2021 Category: International Medicine & Public Health Source Type: research

Repurposing existing medications for coronavirus disease 2019: protocol for a rapid and living systematic review
DiscussionThe challenge posed by COVID-19 requires not just a rapid review of drugs that can be repurposed but also a sustained effort to integrate new evidence into a living systematic review.Trial registrationPROSPERO 2020CRD42020175648 (Source: Systematic Reviews)
Source: Systematic Reviews - May 7, 2021 Category: International Medicine & Public Health Source Type: research

Knowledge of prostate cancer presentation, etiology, and screening practices among women: a mixed-methods systematic review
ConclusionsModerate knowledge of women on the signs and symptoms and the causes and risk factors of prostate cancer was associated with education. These findings provide vital information for the prevention and control of prostate cancer and encourage policy-makers to incorporate health promotion and awareness campaigns in health policies to improve knowledge and awareness of prostate cancer globally.Systematic review registrationOpen Science Framework (OSF) registration DOI:https://doi.org/10.17605/OSF.IO/BR456 (Source: Systematic Reviews)
Source: Systematic Reviews - May 6, 2021 Category: International Medicine & Public Health Source Type: research

Carotid endarterectomy with patch angioplasty versus primary closure in patients with symptomatic and significant stenosis: a systematic review with meta-analyses and trial sequential analysis of randomized clinical trials
AbstractBackgroundPatch angioplasty in conventional carotid endarterectomy is suggested to reduce the risk of restenosis and recurrent ipsilateral stroke compared with primary closure. A systematic review of randomized clinical trials is needed to compare outcomes (benefits and harms) of both techniques.MethodsSearches (CENTRAL, PubMed/MEDLINE, EMBASE, and other databases) were last updated 3rd of January 2021. We included randomized clinical trials comparing carotid endarterectomy with patch angioplasty versus primary closure of the arterial wall in patients with a symptomatic and significant (>  50%) carotid st...
Source: Systematic Reviews - May 6, 2021 Category: International Medicine & Public Health Source Type: research

Effect of community-based interventions targeting female sex workers along the HIV care cascade in sub-Saharan Africa: a systematic review and meta-analysis
ConclusionsThe evidence brought forward from this review shows that the effect of community-based interventions varies across the different stages of HIV care cascade. A broad package of interventions including a combination of behavioral, biomedical, and structural, designed with specific strategies, unique to each cascade stage appears to be more effective, although information on long-term treatment outcomes and the extent to which FSWs remain engaged in care is sparse. There is need to conduct a further research to deepen the assessment of the effectiveness of community-based interventions on HIV care cascade for FSWs....
Source: Systematic Reviews - May 6, 2021 Category: International Medicine & Public Health Source Type: research