A systematic review of the perceptions of adolescents on graphic health warnings and plain packaging of cigarettes
ConclusionsGraphic health warnings and plain packaging appear to increase adolescent awareness of the dangers of tobacco use. Further research into the most effective warnings to use in combination with plain packaging is needed to ensure the greatest reduction in tobacco use and prevent tobacco-attributable morbidity and mortality in this vulnerable population. (Source: Systematic Reviews)
Source: Systematic Reviews - January 17, 2019 Category: International Medicine & Public Health Source Type: research

Defining loneliness in older adults: protocol for a systematic review
DiscussionThe results of this systematic review can present a more accurate definition of loneliness for researchers who aim at conducting new primary and secondary studies on this subject.Systematic review registrationCRD42017058729 (Source: Systematic Reviews)
Source: Systematic Reviews - January 17, 2019 Category: International Medicine & Public Health Source Type: research

Perioperative use of gabapentinoids for the management of postoperative acute pain: protocol of a systematic review and meta-analysis
DiscussionOur study will provide the best level of evidence to inform the effect of gabapentinoids in the management of postoperative acute pain.Systematic review registrationPROSPEROCRD42017067029 (Source: Systematic Reviews)
Source: Systematic Reviews - January 16, 2019 Category: International Medicine & Public Health Source Type: research

Machine learning algorithms for systematic review: reducing workload in a preclinical review of animal studies and reducing human screening error
ConclusionsThis work has confirmed the performance and application of ML algorithms for screening in systematic reviews of preclinical animal studies. It has highlighted the novel use of ML algorithms to identify human error. This needs to be confirmed in other reviews with different inclusion prevalence levels, but represents a promising approach to integrating human decisions and automation in systematic review methodology. (Source: Systematic Reviews)
Source: Systematic Reviews - January 15, 2019 Category: International Medicine & Public Health Source Type: research

Systematic mapping of checklists for assessing transferability
ConclusionsWe identified a variety of checklists intended to support end users (researchers, review authors, practitioners, etc.) to assess transferability or related concepts. While four of these checklists are intended for use in systematic reviews of effectiveness, we found no checklists for qualitative evidence syntheses or for the field of social welfare practice or policy. Furthermore, none of the identified checklists for review authors included guidance to on how to assess transferability, or present assessments in a systematic review. The results of the content analysis can serve as the basis for developing a comp...
Source: Systematic Reviews - January 14, 2019 Category: International Medicine & Public Health Source Type: research

Strategies for incorporating patient-reported outcomes in the care of people with chronic kidney disease (PRO kidney): a protocol for a realist synthesis
DiscussionThe utilization of PROs remains a challenge in nephrology. The findings from this synthesis will provide a framework to guide both policy makers and practitioners on how to enhance person-centered care through successful utilization of PROs across individual and aggregate levels in nephrology.Systematic review registrationPROSPERO CRD42017056063 (Source: Systematic Reviews)
Source: Systematic Reviews - January 12, 2019 Category: International Medicine & Public Health Source Type: research

A systematic review protocol of stigma among children and adolescents with epilepsy
DiscussionFindings from this review will document the burden of stigma of epilepsy and the common contributing factors, which will form the building blocks of interventions that address this health challenge.Systematic review registrationPROSPEROCRD42017058957 (Source: Systematic Reviews)
Source: Systematic Reviews - January 12, 2019 Category: International Medicine & Public Health Source Type: research

The impact of different inclusion decisions on the comprehensiveness and complexity of overviews of reviews of healthcare interventions
ConclusionsOverlapping SRs present a methodological challenge for overview authors. This study demonstrates that different inclusion decisions affect the comprehensiveness and results of overviews in different ways, depending in part on whether Cochrane SRs examine all intervention comparisons relevant to the overview. Study results were used to develop an evidence-based decision tool that provides practical guidance for overview authors. (Source: Systematic Reviews)
Source: Systematic Reviews - January 11, 2019 Category: International Medicine & Public Health Source Type: research

Effects of testosterone therapy for women: a systematic review and meta-analysis protocol
DiscussionThis comprehensive systematic review with meta-analysis will provide the foundation for the development of evidence-based clinical practice guidelines that will address benefits and risks of testosterone therapy, when treatment might be appropriate or inappropriate, areas of clinical uncertainty and the basis for assessment and monitoring of patients.Systematic review registrationPROSPERO registration number:CRD42018104073 (Source: Systematic Reviews)
Source: Systematic Reviews - January 11, 2019 Category: International Medicine & Public Health Source Type: research

The prevalence of phantom limb pain and associated risk factors in people with amputations: a systematic review protocol
AbstractBackgroundThe prevalence of phantom limb pain (PLP) in people with amputations is unclear because of the conflicting reports across the literature. It is proposed that the conflicting reports on the prevalence of PLP are a consequence of variations in the time period during which the studies were undertaken, countries in which the studies were conducted and recruitment processes implemented during collection of epidemiological data. In consideration of these factors, we aim to gather and critically appraise relevant literature to determine the prevalence estimate of and risk factors for PLP in people with amputatio...
Source: Systematic Reviews - January 10, 2019 Category: International Medicine & Public Health Source Type: research

Effectiveness of architectural separation of septic and aseptic operating theatres for improving process quality and patient outcomes: a systematic review
ConclusionsThis review did not identify evidence in favour nor against architectural separation of septic or aseptic operating theatre. Specifically, there is no evidence of a harmful effect of architectural separation. Unless prospective studies, ideally randomised trials, will be available, it is unjustified to call for abolishing established hospital structures. Future investigations must address patient-centered endpoints, surgical site infections, process quality and hospital economy.Systematic review registrationPROSPERO (International prospective register of systematic reviews): CRD42018086568. (Source: Systematic Reviews)
Source: Systematic Reviews - January 9, 2019 Category: International Medicine & Public Health Source Type: research

Value of gait analysis for measuring disease severity using inertial sensors in patients with multiple sclerosis: protocol for a systematic review and meta-analysis
DiscussionIdentifying changes in disease state throughout the course of MS is essential for optimal care. Current clinical and performance tests allow for identifying advanced gait alteration but lack sensitivity to detect subtle gait change. IMUs can be easily used in clinical practice to quantify gait in MS patients. Nevertheless, whether these outcomes are clinically relevant is uncertain because no study has evaluated their correlation with disease severity across different settings. This systematic review and meta-analysis would bring insight into the potential of this outcome as a marker of disease evolution.Systemat...
Source: Systematic Reviews - January 8, 2019 Category: International Medicine & Public Health Source Type: research

Mapping variation in intervention design: a systematic review to develop a program theory for patient navigator programs
ConclusionsThere is considerable heterogeneity in intervention content across patient navigator interventions. Our results provide a schema from which to develop PN interventions and illustrate how an evidence-based model was used to develop a real-world PN intervention. Our findings also highlight a critical need to improve the reporting of intervention components to facilitate translation.Systematic review registrationPROSPERO CRD42013005857 (Source: Systematic Reviews)
Source: Systematic Reviews - January 8, 2019 Category: International Medicine & Public Health Source Type: research

Effectiveness of text messaging interventions on prevention, detection, treatment, and knowledge outcomes for sexually transmitted infections (STIs)/HIV: a systematic review and meta-analysis
ConclusionsThe effectiveness of text message interventions is equivocal. While text messaging has the potential to enhance the delivery of STI/HIV interventions, program planners are encouraged to evaluate any SMS intervention to ensure it is achieving the desired result.Systematic review registrationPROSPEROCRD42013006503 (Source: Systematic Reviews)
Source: Systematic Reviews - January 8, 2019 Category: International Medicine & Public Health Source Type: research

Health solutions to improve post-intensive care outcomes: a realist review protocol
The objective of the proposed review is to provide the theoretical scaffolding to transform the care of survivors of critical illness by a synthesis of relevant clinical and healthcare service programs.MethodsRealist review will be used to develop and refine a theoretical understanding of why, how, for whom, and in what circumstances post-ICU program impact ICU survivors ’ outcomes. This review will follow the recommended five steps of realist review which include (1) clarifying the scope of the review and articulating a preliminary program theory, (2) searching for evidence, (3) appraising primary studies and extrac...
Source: Systematic Reviews - January 8, 2019 Category: International Medicine & Public Health Source Type: research

Mapping evidence on charitable food assistance system ’s compliance with safety and general hygiene requirements in Africa and the rest of the world: a systematic scoping review protocol
This study will be conducted through a systematic scoping review. We will search for literature from the following electronic databases: African Index Medicus, PubMed, Google Scholar, EBSCOhost (MEDLINE with full text, Academic Search Complete, MEDLINE) and open access for unpublished theses and dissertations. Articles will also be searched through the ‘Cited by’ search as well as citations included in the reference lists of included articles. Websites, such as the World Health Organization (WHO) and the Departments of Health websites, will be searched for policies and guidelines for food charity practice. Stud...
Source: Systematic Reviews - January 8, 2019 Category: International Medicine & Public Health Source Type: research

Clinical applications of palmitoylethanolamide in pain management: protocol for a scoping review
DiscussionThis scoping review aims to describe the clinical applications of the PEA in chronic pain management and its outcome.Scoping review registrationOpen Science Frameworkhttps://osf.io/74tmx/. (Source: Systematic Reviews)
Source: Systematic Reviews - January 8, 2019 Category: International Medicine & Public Health Source Type: research

Protocol for a systematic review of the effects of interventions for vaccine stock management
DiscussionWe believe that the findings of this review will serve as valuable information for policy makers on ways to improve vaccine stock management and vaccine availability. When vaccine availability is improved, those who need them, especially children, will be adequately protected from vaccine-preventable diseases.Systematic review registrationPROSPERO CRD42018092215 (Source: Systematic Reviews)
Source: Systematic Reviews - January 8, 2019 Category: International Medicine & Public Health Source Type: research

Risk of bias assessment of sequence generation: a study of 100 systematic reviews of trials
ConclusionSystematic reviews of interventions frequently rate randomised trials as high or unclear ROB for sequence generation. In general, Cochrane reviews were more transparent than non-Cochrane reviews in ROB and quality of evidence assessment. The scientific community should more strongly promote consistent ROB assessment for sequence generation to minimise selection bias and support transparent quality of evidence assessment. Consistency ensures that appropriate conclusions are drawn from the data. (Source: Systematic Reviews)
Source: Systematic Reviews - January 8, 2019 Category: International Medicine & Public Health Source Type: research

Cortisol levels in different tissue samples in posttraumatic stress disorder patients versus controls: a systematic review and meta-analysis protocol
DiscussionIn line with previous reviews, we expect that cortisol levels will be lower in PTSD patients than in controls, but that patterns may vary somewhat according to the tissue sample in which cortisol is measured. This systematic review will assist in developing a better understanding of the acute and chronic patterns of basal cortisol secretion in PTSD and will inform future research.Systematic review registrationPROSPEROCRD42018091874 (Source: Systematic Reviews)
Source: Systematic Reviews - January 7, 2019 Category: International Medicine & Public Health Source Type: research

Evidence on point-of-care diagnostics for assessment of nutritional biochemical markers as an integral part of maternal services in low- and middle-income countries: systematic scoping review protocol
DiscussionWe anticipate finding relevant literature on point-of-care diagnostic services for assessment of biochemical indicators as part of maternal services in low- and middle-income countries. The evidence obtained from the included studies when summarised will help to guide future research. (Source: Systematic Reviews)
Source: Systematic Reviews - January 5, 2019 Category: International Medicine & Public Health Source Type: research

The association between socioeconomic status and pandemic influenza: protocol for a systematic review and meta-analysis
This study will provide the first systematic review of research on the relation between SES and pandemic outcomes. The findings will be relevant for health policy in helping to assess whether people of low socioeconomic status should be prioritized for vaccines in preparedness plans for pandemic influenza. The review will also contribute to the research literature by providing pooled estimates of effect sizes as inputs into power calculations of future studies.Systematic review registrationPROSPERO 87922 (Source: Systematic Reviews)
Source: Systematic Reviews - January 4, 2019 Category: International Medicine & Public Health Source Type: research

The Evidence Project risk of bias tool: assessing study rigor for both randomized and non-randomized intervention studies
ConclusionsStrengths of the tool include its applicability to a range of study designs, from randomized trials to various types of observational and quasi-experimental studies. It is relatively easy to use and interpret and can be applied to a range of review topics without adaptation, facilitating comparability across reviews. Limitations include the lack of potentially relevant items measured in other tools and potential threats to validity of some items. To date, the tool has been applied in over 30 reviews. We believe it is a practical option for assessing risk of bias in systematic reviews of interventions that includ...
Source: Systematic Reviews - January 3, 2019 Category: International Medicine & Public Health Source Type: research

Prevalence of metabolic syndrome among HIV-positive and HIV-negative populations in sub-Saharan Africa —a systematic review and meta-analysis
ConclusionsThe high range of MetS prevalence in the HIV-infected population compared to the uninfected population highlights the possible presence of HIV related drivers of MetS. Also, the reported high rate of MetS, irrespective of HIV status, indicates a major metabolic disorder epidemic that requires urgent prevention and management programs in SSA. Similarly, in the era of universal test and treat strategy among people living with HIV cohorts, routine check-up of MetS sub-components is required in HIV management as biomarkers.Systematic review registrationPROSPERO CRD42016045727 (Source: Systematic Reviews)
Source: Systematic Reviews - January 3, 2019 Category: International Medicine & Public Health Source Type: research

Sonographic reference values of median nerve cross-sectional area: a protocol for a systematic review and meta-analysis
DiscussionA comprehensive set of normative reference values of median nerve CSA will reduce variability across studies, allowing future research to more accurately evaluate and establish diagnostic thresholds. Additionally, normative values can serve as a reference for evaluating treatment outcomes and provide a means to investigate and understand minor nuances in CSA changes that may be indicative of preclinical stages of median nerve pathology.Systematic review registrationPROSPERO 2016CRD42016037286 (Source: Systematic Reviews)
Source: Systematic Reviews - January 3, 2019 Category: International Medicine & Public Health Source Type: research

How do midwives facilitate women to give birth during physiological second stage of labour? A protocol for a systematic review
DiscussionA midwife ’s practice can be influenced by education and cultural practices but ultimately it should be informed by up-to-date research evidence. By analysing and synthesising the results of the studies, this systematic review will provide valuable insight into high-quality evidence-based midwifery care, wh ich can inform practice, education and future research.Systematic review registrationPROSPEROCRD42018088300 (Source: Systematic Reviews)
Source: Systematic Reviews - January 3, 2019 Category: International Medicine & Public Health Source Type: research

Outcomes after toxic alcohol poisoning: a systematic review protocol
The objective of this study is to summarize existing evidence on short- and long-term outcomes of patients following toxic alcohol poisonings, including methanol, ethylene glycol, isopropanol, propylene glycol, and diethylene glycol.MethodsA literature search in PubMed, MEDLINE, and EMBASE will be performed based on pre-determined criteria. There will be no restrictions on publication dates or languages. The search will be supplemented by manual scan of bibliographies of eligible studies and gray literature assessment. Observational studies and clinical trials will be included in this review. Once eligible studies have bee...
Source: Systematic Reviews - December 28, 2018 Category: International Medicine & Public Health Source Type: research

Using tocolysis in pregnant women with symptomatic placenta praevia does not significantly improve prenatal, perinatal, neonatal and maternal outcomes: a systematic review and meta-analysis
ConclusionIn women with symptomatic placenta praevia, there is no significant effect on pregnancy prolongation with the use of tocolysis. Tocolysis has no significant effect on other prenatal, perinatal, neonatal and maternal outcomes among women with symptomatic placenta praevia.Systematic review registrationPROSPEROCRD42018091513 (Source: Systematic Reviews)
Source: Systematic Reviews - December 27, 2018 Category: International Medicine & Public Health Source Type: research

Screening for chlamydia and/or gonorrhea in primary health care: protocol for systematic review
DiscussionThe results section of the review will include a description of all studies, results of all analyses, including planned subgroup and sensitivity analyses, and evidence profiles and summary of findings tables incorporating assessment based on Grading of Recommendations Assessment, Development and Evaluation (GRADE) methods to communicate our confidence in the estimates of effect. We will compare our findings to others and discuss limitations of the review and available literature. The findings will be used by the CTFPHC —supplemented by consultations with patients and stakeholders and from other sources on i...
Source: Systematic Reviews - December 26, 2018 Category: International Medicine & Public Health Source Type: research

Effect of the duration of antimicrobial exposure on the development of antimicrobial resistance (AMR) for macrolide antibiotics: protocol for a systematic review with a network meta-analysis
DiscussionEstablishing the relationship between the duration of antimicrobial exposure and development of, or selection for, resistance will inform the design of antimicrobial prescriptions, treatment guidelines and the behaviour of both physicians and patients. This work will therefore be a strong contribution towards the full realisation of current antimicrobial resistance stewardship strategies.Systematic review registrationPROSPEROCRD42018089275 (Source: Systematic Reviews)
Source: Systematic Reviews - December 23, 2018 Category: International Medicine & Public Health Source Type: research

Life satisfaction and positive and negative feelings of workers: a systematic review protocol
DiscussionAs far as we know, this is the first systematic review related specially to workers ’ subjective well-being. We hope that this study contributes to the “well-being at work” discussion and also to the development of effective interventions, used outside and inside organizations, that could improve well-being scores and increase correlate variables scores such as general health , social relations, and quality of life.Systematic review registrationPROSPEROCRD42016039520 (Source: Systematic Reviews)
Source: Systematic Reviews - December 23, 2018 Category: International Medicine & Public Health Source Type: research

Prediction of exertional lower extremity musculoskeletal injury in tactical populations: protocol for a systematic review and planned meta-analysis of prospective studies from 1955 to 2018
DiscussionThis systematic review and planned meta-analysis will comprehensively evaluate ELEI risk factors. Information gained will inform injury prevention protocols, facilitate the use of improved measurements, and identify requirements for future research.Trial RegistrationThe systematic review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 3 Jan 2018 (registration numberCRD42018056977). (Source: Systematic Reviews)
Source: Systematic Reviews - December 23, 2018 Category: International Medicine & Public Health Source Type: research

Protocol for treatment of Achilles tendon ruptures; a systematic review with network meta-analysis
The objectives of this review are to synthesize the evidence on the management options for acute Achilles tendon rupture and identify which treatment gives the best functional outcomes.MethodsA systematic review with NMA is planned. An electronic literature search will be performed in conjunction with an experienced information specialist in MEDLINE, EMBASE, CINAHL, PEDro, and the Cochrane Central Register of Controlled Trials. We will include randomized controlled trials with a minimum 6-month follow-up. Two independent reviewers will screen citations for eligibility, extract study data, and perform risk of bias assessmen...
Source: Systematic Reviews - December 23, 2018 Category: International Medicine & Public Health Source Type: research

Barriers and facilitating factors in the prevention of diabetes type II and gestational diabetes in vulnerable groups: protocol for a scoping review
DiscussionThe results will be used to inform the National education and communication strategy on diabetes mellitus in Germany. In particular, the results will be discussed in focus groups of experts to develop recommendations for developing preventive measures targeting vulnerable groups.Systematic review registrationPROSPERO does not register scoping reviews. (Source: Systematic Reviews)
Source: Systematic Reviews - December 23, 2018 Category: International Medicine & Public Health Source Type: research

The risk of bias in observational studies of exposures (ROBINS-E) tool: concerns arising from application to observational studies of exposures
ConclusionsOur experience suggests that the ROBINS-E tool does not meet the need for an international standard for evaluating human observational studies for questions of harm relevant to public and environmental health. We propose that a simpler tool, based on empirical evidence of bias, would provide accurate measures of risk of bias and is more likely to meet the needs of the environmental and public health community. (Source: Systematic Reviews)
Source: Systematic Reviews - December 21, 2018 Category: International Medicine & Public Health Source Type: research

A systematic review of enteric dysbiosis in chronic fatigue syndrome/myalgic encephalomyelitis
AbstractBackgroundChronic fatigue syndrome or myalgic encephalomyelitis (CFS/ME) is an illness characterised by profound and pervasive fatigue in addition to a heterogeneous constellation of symptoms. The aetiology of this condition remains unknown; however, it has been previously suggested that enteric dysbiosis is implicated in the pathogenesis of CFS/ME. This review examines the evidence currently available for the presence of abnormal microbial ecology in CFS/ME in comparison to healthy controls, with one exception being probiotic-supplemented CFS/ME patients, and whether the composition of the microbiome plays a role ...
Source: Systematic Reviews - December 20, 2018 Category: International Medicine & Public Health Source Type: research

Deworming in non-pregnant adolescent girls and adult women: a systematic review and meta-analysis
ConclusionsMass deworming probably reduces the prevalence of soil-transmitted helminth infections but may have little or no effect on anaemia and iron-deficiency in adolescent girls and non-pregnant women in comparison to no intervention or placebo. We are uncertain about the effect on severe anaemia. These results are limited by sparse data and the moderate to very low quality of evidence available.Systematic review registrationThe protocol was registered in PROSPERO (registration number:CRD42016039557).  Primary source of funding: Evidence and Programme Guidance unit, Department of Nutrition for Health and Developme...
Source: Systematic Reviews - December 20, 2018 Category: International Medicine & Public Health Source Type: research

CSF and blood biomarkers in amyotrophic lateral sclerosis: protocol for a systematic review and meta-analysis
DiscussionWe will systematically review the literature and analyze studies of biomarker level in CSF and peripheral blood of patients with ALS and controls. The results will help us to identify biomarkers with possible diagnostic and prognostic value.Systematic review registrationPROSPEROCRD42017078127 (Source: Systematic Reviews)
Source: Systematic Reviews - December 20, 2018 Category: International Medicine & Public Health Source Type: research

Teaching improvement science to paramedicine students: protocol for a systematic scoping review
DiscussionTo the knowledge of the authors, this is the first review that will systematically explore and critically appraise the current state of research evidence regarding strategies to teach improvement science specifically to paramedicine students. It is anticipated that the findings of this review will help to inform academics, developers of paramedicine teaching curricula, and researchers who are planning projects in this area.Systematic review registrationScoping reviews are currently not eligible for registration on the international prospective register of systematic reviews (i.e., PROSPERO). (Source: Systematic Reviews)
Source: Systematic Reviews - December 20, 2018 Category: International Medicine & Public Health Source Type: research

Quality appraisal of workers ’ wellbeing measures: a systematic review protocol
This study seeks to identify the most valid and reliable measure/s of workers ’ wellbeing.MethodsMeasures will be included if they were (1) designed for measuring workers ’ wellbeing and (2) available in English. We will use a three-staged electronic search strategy to identify studies that include measures that meet the inclusion criteria: (1) electronic bibliographic databases for published work, (2) reference lists of studies with included measures, and (3) the reference list of previously published reviews. The following electronic bibliographic databases will be searched: OVID: psycINFO, psycTESTS, Cochran...
Source: Systematic Reviews - December 20, 2018 Category: International Medicine & Public Health Source Type: research

Effectiveness and components of self-management interventions in adult cancer survivors: a protocol for a systematic review and planned meta-analysis
DiscussionThe results of this systematic review will add to previous reviews and expand the existing knowledge base of the effectiveness and active components of self-management interventions for adult cancer survivors.Systematic review registrationPROSPERO CRD42018085300 (Source: Systematic Reviews)
Source: Systematic Reviews - December 20, 2018 Category: International Medicine & Public Health Source Type: research

Health outcomes of maternal smoking during pregnancy and postpartum period for the mother and infant: protocol for an umbrella review
DiscussionExisting systematic reviews focus on the impact of smoking during pregnancy on a specific health condition. This review aims to analyse current evidence on the overall health outcomes associated with smoking whilst pregnant by providing an overview of evidence from systematic reviews.Systematic review registrationPROSPEROCRD42018086350. (Source: Systematic Reviews)
Source: Systematic Reviews - December 19, 2018 Category: International Medicine & Public Health Source Type: research

Evidence of promoting prevention and the early detection of breast cancer among women, a hospital-based education and screening interventions in low- and middle-income countries: a systematic review protocol
DiscussionWe hope to find relevant studies reporting evidence on promoting prevention and the early detection of breast cancer among women in a hospital-based education and screening interventions in low- and middle-income countries. The evidence obtained from the included studies when summarized will help guide future research. The study results will be disseminated electronically and in print. Also, it will be presented at conferences related to breast cancer.Systematic review registrationThe protocol has been registered with PROSPERO, with registration number CRD42017077818. (Source: Systematic Reviews)
Source: Systematic Reviews - December 14, 2018 Category: International Medicine & Public Health Source Type: research

Protocol for a systematic review and meta-analysis of research on the associations between workplace bullying and sleep
DiscussionThis review and meta-analysis will be among the first to systematically explore and integrate the evidence available on the association between exposure to bullying and sleep, as well as on the mediating and moderating factors that can govern this associations. By gathering and summarizing information about potential factors that can explain when and how bullying is related to sleep, the findings from this study will provide directions for future research and provide practitioners and clinicians with an understanding about the nature and consequences of workplace bullying and point to directions for relevant inte...
Source: Systematic Reviews - December 13, 2018 Category: International Medicine & Public Health Source Type: research

Interventions for behaviour change and self-management in stroke secondary prevention: protocol for an overview of reviews.
DiscussionThis overview will comprehensively bring together the best available evidence supporting person-centred, stroke secondary prevention strategies in an accessible format, identifying current knowledge gaps. (Source: Systematic Reviews)
Source: Systematic Reviews - December 13, 2018 Category: International Medicine & Public Health Source Type: research

Current state and future directions of technology-based ecological momentary assessments and interventions for major depressive disorder: protocol for a systematic review
The objective of this systematic review is to provide the state of the art of technology-based EMAs and EMIs for major depressive disorder (MDD), with the aim of leading the way to possible future directions for the clinical practice.MethodsWe will conduct a systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. Data sources will include two bibliographic databases, PubMed and Web of Science (Web of Knowledge), supplemented by searches for unpublished or ongoing studies. Eligible studies will report data for adult ( ≥ 18 years old) with a primary...
Source: Systematic Reviews - December 13, 2018 Category: International Medicine & Public Health Source Type: research

Resting blood pressure reductions following handgrip exercise training and the impact of age and sex: a systematic review and narrative synthesis
ConclusionsHandgrip exercise is an effective modality for resting BP reduction resulting in clinically significant reductions for men and women of all ages.Systematic review registrationPROSPEROCRD42015019792 (Source: Systematic Reviews)
Source: Systematic Reviews - December 12, 2018 Category: International Medicine & Public Health Source Type: research

A systematic review of the risk factors for suicidal ideation, suicidal attempt and completed suicide among children and adolescents in sub-Saharan Africa between 1986 and 2018: protocol for a systematic review of observational studies
DiscussionThis protocol describes a systematic review of observational studies reporting completed suicide, suicidal ideation and suicidal attempt among children and adolescents in sub-Saharan Africa. We anticipate that once this review is complete and published, our findings will be of interest to adolescents with suicidal behaviour, their families and caregivers, clinicians and other healthcare professionals, scientists and policy makers.Systematic review registrationPROSPERO International prospective register of systematic reviews:CRD42016048610. (Source: Systematic Reviews)
Source: Systematic Reviews - December 12, 2018 Category: International Medicine & Public Health Source Type: research

Angioplasty and stenting for below the knee ulcers in diabetic patients: protocol for a systematic review
DiscussionWhile there are several available endovascular techniques for revascularisation, it is unclear which technique has better outcomes for ulcers below the knee in diabetic patients. A systematic review is required to validate and demonstrate these techniques and their outcomes to allow an evidence-based clinical decision.Systematic review registrationPROSPEROCRD42017065171 (Source: Systematic Reviews)
Source: Systematic Reviews - December 11, 2018 Category: International Medicine & Public Health Source Type: research

Interventions integrating health and academic interventions to prevent substance use and violence: a systematic review and synthesis of process evaluations
ConclusionSeveral useful facilitating and inhibiting factors linked to the implementation of interventions that integrate academic and health education for reduced substance use and/or violence were identified, providing tentative but insightful evidence of context-specific issues that may impact intervention success. However, overall, there is still a considerable gap in our understanding of how to achieve the successful implementation of these interventions. (Source: Systematic Reviews)
Source: Systematic Reviews - December 6, 2018 Category: International Medicine & Public Health Source Type: research