The role of imams and mosques in health promotion in Western societies —a systematic review protocol
DiscussionThis systematic review will elucidate the role and effectiveness of imams and mosques in health promotion in Western societies. If the use of imams and mosques is shown to be effective, this will encourage further research in Western Muslim communities that effectively utilise imams and mosques as part of novel strategies and interventions for health promotion in this group. The review will also aid policy makers in Western societies with a view to tackling and potentially reversing the problem of increasing ethnic minority health inequality.Systematic review registrationPROSPERO (CRD42015020166) (Source: Systematic Reviews)
Source: Systematic Reviews - February 2, 2017 Category: Global & Universal Source Type: research

Ethical challenges related to assistive product access for older adults and adults living with a disability: a scoping review protocol
DiscussionOur scoping review findings will focus on and provide insight about the models, frameworks, and principles that have been used to understand ethical challenges related to technology access and procurement. We will use the findings to help inform a series of citizen panels in Canada to identify Canadians ’ values and preferences for enhancing equitable access to assistive products. (Source: Systematic Reviews)
Source: Systematic Reviews - February 1, 2017 Category: Global & Universal Source Type: research

Does knowledge brokering improve the quality of rapid review proposals? A before and after study
ConclusionsThis study found that knowledge brokering increased the perceived clarity of information provided in Evidence Check rapid review proposals and the confidence of reviewers that they could meet policy makers ’ needs. Further research is needed to identify how the knowledge brokering process achieves these improvements and to test the applicability of the findings in other rapid review programs. (Source: Systematic Reviews)
Source: Systematic Reviews - January 28, 2017 Category: Global & Universal Source Type: research

Rational and design of an individual participant data meta-analysis of spinal manipulative therapy for chronic low back pain —a protocol
DiscussionWe will analyze IPD for LBP trials in which SMT is one of the interventions. IPD meta-analysis has been shown to be more reliable and valid than aggregate data meta-analysis, although this difference might also be attributed to the number of studies that can be used or the amount of data that can be utilized. Therefore, this project may identify important gaps in our knowledge with respect to prognostic factors of treatment effects.Systematic review registration:PROSPEROCRD42015025714 (Source: Systematic Reviews)
Source: Systematic Reviews - January 26, 2017 Category: Global & Universal Source Type: research

A protocol for a systematic literature review: comparing the impact of seasonal and meteorological parameters on acute respiratory infections in Indigenous and non-Indigenous peoples
Discussion and registrationThis protocol paper describes our systematic review methods to identify and analyze relevant ARI, season, and meteorological literature with robust reporting. The results are intended to improve our understanding of potential associations between seasonal and meteorological parameters and ARI and, if identified, whether this association varies by place, population, or other characteristics. The protocol is registered in the PROSPERO database (#38051). (Source: Systematic Reviews)
Source: Systematic Reviews - January 26, 2017 Category: Global & Universal Source Type: research

Methods for objectively assessing clinical masticatory performance: protocol for a systematic review
This study protocol describes a systematic review that intends to (i) identify methods to objectively assess clinical masticatory performance and (ii) evaluate psychometric properties (such as validity and reliability) of the identified methods. A systematic literature search is required to do so in these sources: MEDLINE (Ovid), Embase (embase.com), Web of Science Core Collection (Thomson Reuters), Cochrane (Wiley), and Cinahl (Ebsco).Inclusion criteria: studies in scientific, full-text articles; development articles; validation articles; studies of the general adult population, ages ≥18. Exclusion criteria: topics and...
Source: Systematic Reviews - January 26, 2017 Category: Global & Universal Source Type: research

Measurement tools of resource use and quality of life in clinical trials for dementia or cognitive impairment interventions: protocol for a scoping review
DiscussionThis review will identify the instruments used in clinical trials to collect resource use and quality of life data for dementia or cognitive impairment interventions. This will help to guide the study design of future trial-based economic evaluation of these interventions.Systematic review registrationPROSPEROCRD42016038495 (Source: Systematic Reviews)
Source: Systematic Reviews - January 26, 2017 Category: Global & Universal Source Type: research

Opportunities, challenges and concerns for the implementation and uptake of pelvic floor muscle assessment and exercises during the childbearing years: protocol for a critical interpretive synthesis
The objective of this review is to understand the relationships between individual, professional, inter-professional and organisational opportunities, challenges and concerns that could be essential to maximise the impact of PFMT during childbearing years and to effect the required behaviour change.MethodsFollowing systematic searches to identify sources for inclusion, we shall use a critical interpretive synthesis (CIS) approach to produce a conceptual model, mapping the relationships between individual, professional, inter-professional and organisational factors and the implementation, acceptability and uptake of PFME ed...
Source: Systematic Reviews - January 25, 2017 Category: Global & Universal Source Type: research

Ecological validity of cost-effectiveness models of universal HPV vaccination: a protocol for a systematic review
DiscussionThe proposed systematic review will be the first to assess the ecological validity of cost-effectiveness studies. In the context of sexually transmitted diseases, when this condition is violated, an error in predicting the protective impact of herd immunity would occur. Hence, a vaccination policy informed on ecologically invalid models would potentially expose boys to a residual risk of contracting HPV-induced malignancies.Systematic review registrationPROSPEROCRD42016034145 (Source: Systematic Reviews)
Source: Systematic Reviews - January 25, 2017 Category: Global & Universal Source Type: research

Are we failing young people not in employment, education or training (NEETs)? A systematic review and meta-analysis of re-engagement interventions
ConclusionsThere is some evidence that intensive multi-component interventions effectively decrease unemployment amongst NEETs. The quality of current evidence is limited, leaving policy makers under-served when designing and implementing new programmes, and a vulnerable population neglected.Systematic review registrationPROSPERO CRD42014007535 (Source: Systematic Reviews)
Source: Systematic Reviews - January 25, 2017 Category: Global & Universal Source Type: research

The humanistic and economic burden of chronic wounds: a protocol for a systematic review
This study is a systematic review of multiple databases for studies on adult patients with chronic wounds and with the primary objective to assess the impact on health-related quality of life by category of ulcers, and associated direct and indirect costs. Eligible studies will primary be empirical studies evaluating, describing or comparing measurement of quality of life and economic impact. Two reviewers will independently screen titles and abstracts and select studies involving adults with chronic wounds. These investigators will also independently extract data using a pre-designed data extraction form. Differences in a...
Source: Systematic Reviews - January 24, 2017 Category: Global & Universal Source Type: research

How can pharmacists develop patient-pharmacist communication skills? A realist review protocol
DiscussionThe realist review will provide an analysis of what works when, for whom, how and why, for educational interventions for interpersonal patient-pharmacist communication development. We will also explore barriers to successful communications training and acknowledge any limitations. Ultimately, we plan to provide pharmacy educators with evidence for how best to incorporate educational interventions for communications skills development into pharmacy curricula and for life-long learning opportunities for pharmacists. (Source: Systematic Reviews)
Source: Systematic Reviews - January 23, 2017 Category: Global & Universal Source Type: research

Celebrities ’ impact on health-related knowledge, attitudes, behaviors, and status outcomes: protocol for a systematic review, meta-analysis, and meta-regression analysis
DiscussionThe results of this review will contribute to our understanding of celebrity influences and how to design positive evidence-based celebrity health promotion activities. In addition, these findings can help inform the development of media reporting guidelines pertaining to celebrity health news and provide guidance to public health authorities on whether and how to respond to or work with celebrities.Systematic review registrationPROSPEROCRD42015019268 (Source: Systematic Reviews)
Source: Systematic Reviews - January 21, 2017 Category: Global & Universal Source Type: research

Impact of trauma system structure on injury outcomes: a systematic review protocol
The objective of the study described in this protocol is to systematically review evidence of the impact of trauma system components on clinically significant outcomes including mortality, function and disability, quality of life, and resource utilization.MethodsWe will perform a systematic review of studies evaluating the association between at least one trauma system component (e.g. accreditation by a central agency, interfacility transfer agreements) and at least one injury outcome (e.g. mortality, disability, resource use). We will search MEDLINE, EMBASE, COCHRANE central, and BIOSIS/Web of Knowledge databases, thesis ...
Source: Systematic Reviews - January 21, 2017 Category: Global & Universal Source Type: research

Protocol for a realist review of workplace learning in postgraduate medical education and training
This study will draw from the published literature and programme, and substantive, theories of workplace learning, to describe context, mechanism and outcome configurations for PGMET. This information will be useful to policymakers and practitioners in PGMET, who will be able to apply our findings within their own contexts. Improving the quality of clinical learning environments can improve the performance, humanism and wellbeing of learners and improve the quality and safety of patient care.Systematic review registrationThe review is not registered with the PROSPERO International Prospective Register of Systematic Reviews...
Source: Systematic Reviews - January 19, 2017 Category: Global & Universal Source Type: research

The effects of asking a fertility intention question in primary care settings: a systematic review protocol
The objective of the systematic review is to determine the effectiveness of incorporating questions of pregnancy intention into primary care.MethodsA systematic search of the literature will be conducted for any studies comparing questions of pregnancy intention in primary care settings with no intervention or a control intervention. Types of studies will include randomized controlled trials, non-randomized trials, and observation studies. Participants will include patients of reproductive age presenting to primary health care settings. Interventions will include any assessment of fertility intention and follow-up care com...
Source: Systematic Reviews - January 19, 2017 Category: Global & Universal Source Type: research

What is the relationship between type 2 diabetes mellitus status and the neuroradiological correlates of cerebral small vessel disease in adults? Protocol for a systematic review
This study aims to determine if adults with CSVD and T2DM have a distinct neuroradiologic phenotype.MethodsA systematic search of the literature will be conducted to find articles that report the MRI features of CSVD in a cohort of participants including those with and without type 2 diabetes mellitus (T2DM). A number of databases will be searched including MEDLINE, Embase, CINAHL, and Web of Science. Proceedings and abstracts from key conferences will also be reviewed and relevant journals hand searched for additional papers. The references from selected papers will be scanned. Screening of potential articles, data extrac...
Source: Systematic Reviews - January 17, 2017 Category: Global & Universal Source Type: research

Risk assessment tools to predict location of discharge and need for supportive services for medical patients after discharge from hospital: a systematic review protocol
DiscussionEarly and accurate assessment of patient needs for supportive services after discharge has the potential to improve patient outcomes and health system efficiency. This systematic review will identify factors that can accurately predict location of discharge using existing tools and identify priority knowledge gaps to inform future research.Systematic review registrationPROSPEROCRD42016037144 (Source: Systematic Reviews)
Source: Systematic Reviews - January 17, 2017 Category: Global & Universal Source Type: research

The dynamics of HIV transmission in out of school young heterosexual men in South Africa: a systematic scoping review protocol
DiscussionWe anticipate finding relevant literature on the dynamics of HIV transmission in South African men. Once summarized, data will be useful to guide future research.Systematic review registrationPROSPEROCRD42016039489 (Source: Systematic Reviews)
Source: Systematic Reviews - January 17, 2017 Category: Global & Universal Source Type: research

Determinants and materno-fetal outcomes related to cesarean section delivery in private and public hospitals in low- and middle-income countries: a systematic review and meta-analysis protocol
DiscussionThe proposed systematic review of the CSD rate rise will provide up-to-date evidence in regard to differences in proportions, determinants, and materno-fetal and materno-infant outcomes in perinatal period, between private and public hospitals in LMICs. We believe that this knowledge synthesis will help to shed light on the evidence and support evidence-informed decision-making with a view to addressing the issue in LMICs.Systematic review registrationPROSPEROCRD42016036871 (Source: Systematic Reviews)
Source: Systematic Reviews - January 14, 2017 Category: Global & Universal Source Type: research

Association between diabetes mellitus and multi-drug-resistant tuberculosis: a protocol for a systematic review and meta-analysis
DiscussionIncreases in the burden of non-communicable diseases and aging populations are changing the importance of different risk factors for TB, and the profile of comorbidities and clinical challenges for people with TB. Although classic risk factors and comorbidities such as overcrowding, under-nutrition, silicosis, and HIV infection are crucial to address, chronic conditions like diabetes are important factors that impair host defenses against TB. Thus, undertaking integrated multifaceted approach is remarkably necessary for reducing the burden of DM and successful TB treatment outcome.Systematic review registrationPR...
Source: Systematic Reviews - January 14, 2017 Category: Global & Universal Source Type: research

Therapies for bruxism: a systematic review and network meta-analysis (protocol)
DiscussionThis systematic review aims at identifying and evaluating therapies to treat bruxism. This systematic review may lead to several recommendations, for both patients and researchers, as which is the best therapy for a specific patient case and how future studies need to be designed, considering what is available now and what is the reality of the patient.Systematic review registrationPROSPEROCRD42015023308 (Source: Systematic Reviews)
Source: Systematic Reviews - January 13, 2017 Category: Global & Universal Source Type: research

Characteristics and use of urban health indicator tools by municipal built environment policy and decision-makers: a systematic review protocol
This study aims to identify the nature and characteristics of UHI tools and their use by municipal built environment policy and decision-makers.MethodsHealth and social sciences databases (ASSIA, Campbell Library, EMBASE, MEDLINE, Scopus, Social Policy and Practice and Web of Science Core Collection) will be searched for studies using UHI tools alongside hand-searching of key journals and citation searches of included studies. Advanced searches of practitioner websites and Google will also be used to find grey literature. Search results will be screened for UHI tools, and for studies which report on or evaluate the use of ...
Source: Systematic Reviews - January 13, 2017 Category: Global & Universal Source Type: research

Biofeedback interventions for people with cerebral palsy: a systematic review protocol
DiscussionSeveral studies have investigated biofeedback-based interventions for people with cerebral palsy. However, there is a great variety and limited consensus regarding how to implement biofeedback mechanisms. This systematic review will consolidate the current evidence to direct future study and develop effective biofeedback rehabilitation strategies.Systematic review registrationPROSPERO ID:CRD42016047612 (Source: Systematic Reviews)
Source: Systematic Reviews - January 13, 2017 Category: Global & Universal Source Type: research

Prosodic processing post traumatic brain injury - a systematic review
AbstractBackgroundTraumatic brain injury (TBI) survivors often report difficulties with understanding and producing paralinguistic cues, as well as understanding and producing basic communication tasks. However, a large range of communicative deficits in this population cannot be adequately explained by linguistic impairment. The review examines prosodic processing performance post-TBI, its relationship with injury severity, brain injury localization, recovery and co-occurring psychiatric or mental health issues post-TBIMethodsA systematic review using several databases including MEDLINE, EMBASE, Cochrane, LLBA (Linguistic...
Source: Systematic Reviews - January 4, 2017 Category: Global & Universal Source Type: research

Interventions and assessment tools addressing key concepts people need to know to appraise claims about treatment effects: a systematic mapping review
ConclusionsThere is great potential for developing learning and assessment tools targeting key concepts that people need to understand to assess claims about treatment effects. There is currently no instrument covering assessment of all these key concepts. (Source: Systematic Reviews)
Source: Systematic Reviews - December 29, 2016 Category: Global & Universal Source Type: research

Post-trial follow-up methodology in large randomized controlled trials: a systematic review protocol
DiscussionPost-trial follow-up can provide valuable information about the long-term benefits and hazards of medical interventions. However, it can be logistically challenging and costly. The aim of this systematic review is to describe how trial participants have been followed-up post-trial in order to inform future post-trial follow-up designs.Systematic review registrationNot applicable for PROSPERO registration. (Source: Systematic Reviews)
Source: Systematic Reviews - December 15, 2016 Category: Global & Universal Source Type: research

Colonic thickening on computed tomography —does it correlate with endoscopic findings? A protocol for systematic review
DiscussionIt is extremely useful for the practising clinician to know which patients need further endoscopic evaluation. Even though there are several studies on this issue, none of them have attempted to produce a systematic review. We hope this systematic review will provide a substantiate evidence for future clinical practice.Systematic review registrationPROSPEROCRD42016039378 (Source: Systematic Reviews)
Source: Systematic Reviews - December 13, 2016 Category: Global & Universal Source Type: research

Data extraction for complex meta-analysis (DECiMAL) guide
AbstractAs more complex meta-analytical techniques such as network and multivariate meta-analyses become increasingly common, further pressures are placed on reviewers to extract data in a systematic and consistent manner. Failing to do this appropriately wastes time, resources and jeopardises accuracy. This guide (data extraction for complex meta-analysis (DECiMAL)) suggests a number of points to consider when collecting data, primarily aimed at systematic reviewers preparing data for meta-analysis. Network meta-analysis (NMA), multiple outcomes analysis and analysis combining different types of data are considered in a m...
Source: Systematic Reviews - December 13, 2016 Category: Global & Universal Source Type: research

Pharmacological interventions for delirium in intensive care patients: a protocol for an overview of reviews
The objective of this overview of reviews is to critically assess the evidence of reviews of randomised clinical trials on the effect of pharmacological management and prevention of delirium in ICU patients.Methods/designWe will search for reviews in the following databases: Cochrane Library, MEDLINE, EMBASE, Science Citation Index, BIOSIS, Cumulative Index to Nursing and Allied Health Literature, Latin American and Caribbean Health Sciences Literature, and Allied and Complementary Medicine Database.Two authors will independently select references for inclusion using Covidence, extract data and assess the methodological qu...
Source: Systematic Reviews - December 7, 2016 Category: Global & Universal Source Type: research

Rayyan —a web and mobile app for systematic reviews
ConclusionsRayyan is responsive and intuitive in use with significant potential to lighten the load of reviewers. (Source: Systematic Reviews)
Source: Systematic Reviews - December 5, 2016 Category: Global & Universal Source Type: research

Incidence, causes, and consequences of preventable adverse drug events: protocol for an overview of reviews
DiscussionThis overview will help synthesize the broad degree of information available on this important topic. This review is being performed by members of the Drug Safety and Effectiveness Network along with collaboration from Health Canada, and its findings will be published in a peer-reviewed journal. The results may also inform future research in this area.Systematic review registrationPROSPEROCRD42016043220 (Source: Systematic Reviews)
Source: Systematic Reviews - December 5, 2016 Category: Global & Universal Source Type: research

Carotid artery stenting versus no stenting assisting thrombectomy for acute ischaemic stroke: protocol for a systematic review of randomised clinical trials with meta-analyses and trial sequential analyses
DiscussionThis systematic review of carotid stenting in endovascular management of acute ischaemic stroke in patients with concomitant extracranial carotid lesions and intracranial embolism will assess benefits and harms of this intervention and assesses whether carotid stenting should be encouraged or avoided in acute ischaemic stroke and identify targets for further research.Systematic review registrationPROSPEROCRD42016033346 (Source: Systematic Reviews)
Source: Systematic Reviews - December 1, 2016 Category: Global & Universal Source Type: research

Prognostic biomarkers to identify patients destined to develop severe Crohn ’s disease who may benefit from early biological therapy: protocol for a systematic review, meta-analysis and external validation
DiscussionIf this systematic review and meta-analysis identifies biomarkers that appear sufficiently predictive for subsequent severe disease course, we aim to combine them in a predictive model, followed by external validation using individual patient data. A predictive model able to identify new presentations of Crohn ’s disease destined to develop severe disease subsequently would have considerable clinical utility for patient management.Systematic review registrationPROSPEROCRD42016029363. (Source: Systematic Reviews)
Source: Systematic Reviews - December 1, 2016 Category: Global & Universal Source Type: research

Are digital interventions for smoking cessation in pregnancy effective? A systematic review protocol
DiscussionThis systematic review will provide a detailed synthesis of the effectiveness of current research using digital interventions for smoking cessation in pregnancy, to build on the evidence base and guide the development of future research in this area.Systematic review registrationPROSPEROCRD42016036201 (Source: Systematic Reviews)
Source: Systematic Reviews - December 1, 2016 Category: Global & Universal Source Type: research

Relationship between surgeon volume and outcomes: a systematic review of systematic reviews
ConclusionsWhen taking into account its limitations, this overview can serve as an informational basis for decision makers. Our results seem to support a positive volume-outcome relationship for most procedures/conditions. However, forthcoming reviews should pay more attention to methodology specific to volume-outcome relationship. Due to the lack of information, any numerical recommendations for minimum volume thresholds are not possible. Further research is needed for this issue. (Source: Systematic Reviews)
Source: Systematic Reviews - November 29, 2016 Category: Global & Universal Source Type: research

The impact of oxytocin administration on brain activity: a systematic review and meta-analysis protocol
DiscussionThis systematic review and meta-analysis will be the first pre-registered synthesis of data to identify the neural correlates of OT nasal spray response. The identification of brain regions underlying OT ’s observed effects will help guide future research and better identify treatment targets.Systematic review registrationPROSPEROCRD42016038781 (Source: Systematic Reviews)
Source: Systematic Reviews - November 29, 2016 Category: Global & Universal Source Type: research

A systematic review of patient safety in mental health: a protocol based on the inpatient setting
DiscussionWe believe that this systematic review will make a significant contribution to the advancement of patient safety in mental health inpatient settings. The findings will enable the development and implementation of interventions to improve the quality of care experienced by patients and support the identification of future research priorities.Systematic review registrationPROSPEROCRD42016034057 (Source: Systematic Reviews)
Source: Systematic Reviews - November 29, 2016 Category: Global & Universal Source Type: research

Consideration of health inequalities in systematic reviews: a mapping review of guidance
ConclusionsAdhering to the guidance will require more work for the reviewers. It requires a deeper understanding of how reviewers can operationalise the guidance taking into consideration the barriers and facilitators involved. This has implications not only for understanding the usefulness and burden of the guidance but also for the uptake of guidance and its ultimate goal of improving health inequalities considerations in systematic reviews. (Source: Systematic Reviews)
Source: Systematic Reviews - November 28, 2016 Category: Global & Universal Source Type: research

Network meta-analyses performed by contracting companies and commissioned by industry
ConclusionsThere is a prolific sector of professional contracting companies that perform network meta-analyses. Industry commissions many network meta-analyses, but most are not registered before or published after analyses in the scientific literature. Mechanisms to improve publication rates of network meta-analysis commissioned by industry are warranted. (Source: Systematic Reviews)
Source: Systematic Reviews - November 25, 2016 Category: Global & Universal Source Type: research

Mental contrasting as a behaviour change technique: a systematic review protocol paper of effects, mediators and moderators on health
DiscussionThis will be the first systematic review of mental contrasting as a health behaviour change technique. With sufficient studies, a meta-analysis will be conducted with sensitivity and sub group analyses. If meta-analysis is not appropriate, a narrative synthesis of the reviewed studies will be conducted.Systematic review registrationReview protocol registered on PROSPERO referenceCRD42016034202. (Source: Systematic Reviews)
Source: Systematic Reviews - November 25, 2016 Category: Global & Universal Source Type: research

The impact of mHealth interventions on health systems: a systematic review protocol
DiscussionThe systematic review will inform policy makers, investors, health professionals, technologists and engineers about the impact of mHealth in strengthening the health system. In particular, it will focus on three metrics to determine whether mHealth strengthens the health system, namely quality of, access to and cost of health care services.Systematic review registration: PROSPEROCRD42015026070 (Source: Systematic Reviews)
Source: Systematic Reviews - November 25, 2016 Category: Global & Universal Source Type: research

Melatonin and melatonin agonists to prevent and treat delirium in critical illness: a systematic review protocol
The objective of this review is to synthesize the available  evidence pertaining to the efficacy and safety of MMA for the prevention and treatment of ICU delirium.MethodsWe will search Ovid MEDLINE, Web of Science, EMBASE, PsycINFO, the Cochrane Central Register of Controlled Trials (CENTRAL), and CINAHL to identify studies evaluating MMA in critically ill populations. We will also searchhttp://apps.who.int/trialsearch for ongoing and unpublished studies and PROSPERO for registered reviews. We will not impose restrictions on language, date, or journal of publication. Authors will independently screen for eligibl...
Source: Systematic Reviews - November 24, 2016 Category: Global & Universal Source Type: research

Evaluating Data Abstraction Assistant, a novel software application for data abstraction during systematic reviews: protocol for a randomized controlled trial
We describe the design of a randomized controlled trial (RCT) that compares the relative effectiveness of (A) DAA-facilitated single abstraction plus verification by a second person, (B) traditiona l (non-DAA-facilitated) single abstraction plus verification by a second person, and (C) traditional independent dual abstraction plus adjudication to ascertain the accuracy and efficiency of abstraction.MethodsThis is an online, randomized, three-arm, crossover trial. We will enroll 24 pairs of abstractors (i.e., sample size is 48 participants), each pair comprising one less and one more experienced abstractor. Pairs will be ra...
Source: Systematic Reviews - November 22, 2016 Category: Global & Universal Source Type: research

Assessing the validity of abbreviated literature searches for rapid reviews: protocol of a non-inferiority and meta-epidemiologic study
DiscussionThis will be the first study to assess whether the reduced sensitivity of abbreviated searches has an impact on conclusions across multiple bodies of evidence, not only on effect estimates. (Source: Systematic Reviews)
Source: Systematic Reviews - November 22, 2016 Category: Global & Universal Source Type: research

A mixed-methods systematic review protocol to examine the use of physical restraint with critically ill adults and strategies for minimizing their use
DiscussionWe will use our systematic review findings to produce updated guidelines on physical restraint use for critically ill adults and to develop a professional society-endorsed position statement. This will foster patient and clinician safety by providing clinicians, administrators, and policy makers with a tool to promote minimal and safe use of physical restraint for critically ill adults.Systematic review registrationPROSPEROCRD42015027860 (Source: Systematic Reviews)
Source: Systematic Reviews - November 21, 2016 Category: Global & Universal Source Type: research

The prevalence of novel psychoactive substances (NPS) use in non-clinical populations: a systematic review protocol
DiscussionThis review will describe the distributions of various types of prevalence estimates of NPS use and explore the impact of different population groups and study-related and tempo-geographical variables on characteristics of these distributions over the period of 2010 to 2016.Systematic review registrationPROSPEROCRD42016037020 (Source: Systematic Reviews)
Source: Systematic Reviews - November 21, 2016 Category: Global & Universal Source Type: research

Pharmacological interventions for agitation in patients with traumatic brain injury: protocol for a systematic review and meta-analysis
DiscussionAlthough agitation is frequent following TBI and pharmacological agents that are often used, there is no consensus on the most efficacious and safest strategy to treat these complications. There is a need for an updated systematic review to summarize the evidence in order to inform practice and future research.Systematic review registrationPROSPEROCRD42016033140 (Source: Systematic Reviews)
Source: Systematic Reviews - November 17, 2016 Category: Global & Universal Source Type: research

Meta-analysis, complexity, and heterogeneity: a qualitative interview study of researchers ’ methodological values and practices
ConclusionsTechnical considerations of how to synthesise complex evidence cannot be isolated from questions of the goals and contexts of research. However, decisions about how to analyse data appear to be made in a largely informal way, drawing on tacit expertise, and their relation to these broader questions remains unclear. (Source: Systematic Reviews)
Source: Systematic Reviews - November 16, 2016 Category: Global & Universal Source Type: research

Exploring issues in the conduct of website searching and other online sources for systematic reviews: how can we be systematic?
We present an approach to address some of the challenges. This is particularly relevant when websites are relied upon to identify important literature for a review. We recommend considering the process as three stages and having a considered rationale and sufficient recordkeeping at each stage that balances transparency with practicality of purpose. Advances in technology and recommendations for website providers are briefly discussed. (Source: Systematic Reviews)
Source: Systematic Reviews - November 15, 2016 Category: Global & Universal Source Type: research