Technology for fostering intergenerational connectivity: scoping review protocol
DiscussionThis scoping review focuses on a search of the literature to gain an understanding of what technologies have been used specifically for fostering intergenerational connectivity and to establish what future directions for research could be. To the authors ’ knowledge, it is the first scoping review of its kind. (Source: Systematic Reviews)
Source: Systematic Reviews - December 8, 2017 Category: International Medicine & Public Health Source Type: research

A systematic review of neonatal treatment intensity scores and their potential application in low-resource setting hospitals for predicting mortality, morbidity and estimating resource use
ConclusionExisting neonatal treatment intensity models show promise in predicting mortality and morbidity. There is however low certainty in the evidence on their performance in essential neonatal care in low resource settings as all studies had methodological limitations and were conducted in intensive care. The approach may however be developed further for low resource settings like Kenya because treatment data may be easier to obtain compared to measures of physiological status.Systematic review registrationPROSPERO CRD42016034205 (Source: Systematic Reviews)
Source: Systematic Reviews - December 7, 2017 Category: International Medicine & Public Health Source Type: research

Abnormal placental cord insertion and adverse pregnancy outcomes: a systematic review and meta-analysis
AbstractBackgroundAbnormal placental cord insertion (PCI) includes marginal cord insertion (MCI) and velamentous cord insertion (VCI). VCI has been shown to be associated with adverse pregnancy outcomes. This systematic review and meta-analysis aims to determine the association of abnormal PCI and adverse pregnancy outcomes.MethodsEmbase, Medline, CINAHL, Scopus, Web of Science, ClinicalTrials.gov, and Cochrane Databases were searched in December 2016 (from inception to December 2016). The reference lists of eligible studies were scrutinized to identify further studies. Potentially eligible studies were reviewed by two aut...
Source: Systematic Reviews - December 6, 2017 Category: International Medicine & Public Health Source Type: research

Quantifying heterogeneity in individual participant data meta-analysis with binary outcomes
ConclusionsThe simulation-basedI2 based on a one-stage approach has better performance than the conventionalI2 based on a two-stage approach when there is strong effect modification with high prevalence. (Source: Systematic Reviews)
Source: Systematic Reviews - December 6, 2017 Category: International Medicine & Public Health Source Type: research

Optimal database combinations for literature searches in systematic reviews: a prospective exploratory study
ConclusionsOptimal searches in systematic reviews should search at least Embase, MEDLINE, Web of Science, and Google Scholar as a minimum requirement to guarantee adequate and efficient coverage. (Source: Systematic Reviews)
Source: Systematic Reviews - December 6, 2017 Category: International Medicine & Public Health Source Type: research

Non-conventional dosing of oral anticancer agents in oncology and malignant haematology: a systematic review protocol
DiscussionThis review will identify relevant literature on the topic to inform prescribers working in oncology and malignant haematology. It will also analyse any evidence of the following outcomes: toxicity, treatment adherence and/or QoL outcomes for patients receiving non-standard doses of oral SACT. Limitations in the evidence base may arise from variability in both the type and quality of studies reviewed.Systematic Review RegistrationPROSPEROCRD42017076195. (Source: Systematic Reviews)
Source: Systematic Reviews - December 6, 2017 Category: International Medicine & Public Health Source Type: research

Prevalence, predictors and adverse outcomes of adolescent pregnancy in sub-Saharan Africa: a protocol of a systematic review
DiscussionThis systematic review and meta-analysis is expected to serve as a template for designing adolescent-friendly preventive and control programmes to help curb the ever-growing burden of adolescent pregnancies, and as a guide for future research.Systematic review registrationPROSPEROCRD42017070773 (Source: Systematic Reviews)
Source: Systematic Reviews - December 6, 2017 Category: International Medicine & Public Health Source Type: research

A systematic review of school-based eHealth interventions targeting alcohol use, smoking, physical inactivity, diet, sedentary behaviour and sleep among adolescents: a review protocol
DiscussionIt is anticipated that the results from this review will serve to inform the development of future eHealth multiple health behaviour interventions for adolescents by identifying common characteristics of effective programs and highlighting knowledge gaps in the evidence base.Systematic review registrationPROSPEROCRD42017072163 (Source: Systematic Reviews)
Source: Systematic Reviews - December 6, 2017 Category: International Medicine & Public Health Source Type: research

Global incidence and case fatality rate of pulmonary embolism following major surgery: a protocol for a systematic review and meta-analysis of cohort studies
DiscussionThis systematic review and meta-analysis will provide the most up-to-date epidemiology of PE in patients undergoing major surgery to inform health authorities and identify further research topics based on the remaining knowledge gaps.Systematic review registrationPROSPEROCRD42017065126 (Source: Systematic Reviews)
Source: Systematic Reviews - December 4, 2017 Category: International Medicine & Public Health Source Type: research

Tracheostomy decannulation methods and procedures in adults: a systematic scoping review protocol
DiscussionWe anticipate to find studies that highlight evidence and preference as well as acceptability of TD methods and procedures. We hope to expose knowledge gaps and inform future research. Findings will be disseminated electronically, in print and through peer presentation, conferences and congresses.Systematic review registrationOur systematic review has been registered in PROSPERO:CRD42017072050. (Source: Systematic Reviews)
Source: Systematic Reviews - December 4, 2017 Category: International Medicine & Public Health Source Type: research

Correction to: Diabetes-related information-seeking behaviour: a systematic review
CorrectionDuring the production process for this article [1] some errors were introduced into Table  2. The correct version of Table 2 can be found below; the original article [1] has also been updated with the correct version of Table 2. BMC apologises to the authors and to readers for this error. (Source: Systematic Reviews)
Source: Systematic Reviews - December 4, 2017 Category: International Medicine & Public Health Source Type: research

The sleep and circadian modulation of neural reward pathways: a protocol for a pair of systematic reviews
DiscussionThe findings from this pair of systematic literature reviews will assist in the identification of the pathways involved in the sleep and circadian function modulation of neural reward in healthy individuals, with implications for disorders characterised by dysregulation in sleep, circadian rhythms and reward function.Systematic review registrationPROSPERO CRD42017064994 (Source: Systematic Reviews)
Source: Systematic Reviews - December 2, 2017 Category: International Medicine & Public Health Source Type: research

Systematic reviews of health economic evaluations: a protocol for a systematic review of characteristics and methods applied
The objective of this study was to analyze the methods applied for systematic reviews of health economic evaluations (SR-HE) with a focus on the identification of common challenges.Methods/designThe planned study is a systematic review of the characteristics and methods actually applied in SR-HE. We will combine validated search filters developed for the retrieval of economic evaluations and systematic reviews to identify relevant studies in MEDLINE (via Ovid, 2015-present). To be eligible for inclusion, studies have to conduct a systematic review of full economic evaluations. Articles focusing exclusively on methodologica...
Source: Systematic Reviews - December 2, 2017 Category: International Medicine & Public Health Source Type: research

Interventions to increase adherence in patients taking immunosuppressive drugs after kidney transplantation: a systematic review of controlled trials
ConclusionEducational and behavioral AEI can increase adherence. In particular, multimodal and individualized interventions seem promising. However, because of the small effect, the high risk of bias, and the invalidity of adherence measures, the actual benefit of adherence interventions for an unselected patient population (i.e., including also adherent patients) seems limited. No conclusion is possible for interventions combining adherence-enhancing components that address intentional (behavioral) as well as unintentional adherence (reminder). (Source: Systematic Reviews)
Source: Systematic Reviews - November 29, 2017 Category: International Medicine & Public Health Source Type: research

Evaluating progestogens for prevention of preterm birth international collaborative (EPPPIC) individual participant data (IPD) meta-analysis: protocol
AbstractBackgroundPreterm birth is the most common cause of death and harm to newborn babies. Babies that are born early may have difficulties at birth and experience health problems during early childhood. Despite extensive study, there is still uncertainty about the effectiveness of progestogen (medications that are similar to the natural hormone progesterone) in preventing or delaying preterm birth, and in improving birth outcomes. The Evaluating Progestogen for Prevention of Preterm birth International Collaborative (EPPPIC) project aims to reduce uncertainty about the specific conditions in which progestogen may (or m...
Source: Systematic Reviews - November 28, 2017 Category: International Medicine & Public Health Source Type: research

A comparison of results of empirical studies of supplementary search techniques and recommendations in review methodology handbooks: a methodological review
ConclusionsThere is reasonable consistency between recommended best practice (handbooks) and current practice (methodological studies) as it relates to the application of supplementary search methods.The methodological studies provide useful information on the effectiveness of the supplementary search methods, often seeking to evaluate aspects of the method to improve effectiveness or efficiency. In this way, the studies advance the understanding of the supplementary search methods. Further research is required, however, so that a rational choice can be made about which supplementary search strategies should be used, and w...
Source: Systematic Reviews - November 28, 2017 Category: International Medicine & Public Health Source Type: research

Expediting citation screening using PICo-based title-only screening for identifying studies in scoping searches and rapid reviews
ConclusionsIn this sample of datasets, PICo-based title-only screening was able to expedite citation screening for scoping searches and rapid reviews by reducing the number of citations needed to screen but requires a thorough workup of the potential synonyms and alternative terms. Further research which evaluates the feasibility of this technique with heterogeneous datasets in different fields would be useful to inform the generalisability of this technique. (Source: Systematic Reviews)
Source: Systematic Reviews - November 25, 2017 Category: International Medicine & Public Health Source Type: research

Protocol for a systematic review and meta-analysis on the clinical outcomes and cost of deep inferior epigastric perforator (DIEP) flap versus implants for breast reconstruction
DiscussionThis will be the first systematic review and meta-analysis in available literature comparing the clinical outcomes and cost-effectiveness of DIEP and implants for breast reconstruction. This review is expected to guide worldwide clinical practice for breast reconstruction.Systematic review registrationPROSPEROCRD42017072557. (Source: Systematic Reviews)
Source: Systematic Reviews - November 22, 2017 Category: International Medicine & Public Health Source Type: research

Toward a comprehensive evidence map of overview of systematic review methods: paper 1 —purpose, eligibility, search and data extraction
ConclusionGaps in the evaluation of methods were found for the majority of steps in the framework. More empirical studies are needed to evaluate the methods outlined and provide a comprehensive evidence map. The framework is useful for planning these evaluations and for planning methods required to deal with challenges that arise when conducting an overview. (Source: Systematic Reviews)
Source: Systematic Reviews - November 21, 2017 Category: International Medicine & Public Health Source Type: research

A systematic review describing incidence rate and prevalence of dysvascular partial foot amputation; how both have changed over time and compare to transtibial amputation
ConclusionWhen appropriately grouped by denominator and strata, incidence rates were more homogenous than might be expected. Variation between studies did not necessarily reduce confidence in the conclusion; for example, incidence rate of PFA were many times larger in cohorts with diabetes (94.24 per 100,000 people with diabetes; 95% CI 55.50 to 133.00) compared to those without (3.80 per 100,000 people without diabetes; 95% CI 1.43 to 6.16). It is unclear whether the incidence rates of PFA have changed over time or how they have changed relative to TTA. Further research requires datasets that include a large number of amp...
Source: Systematic Reviews - November 21, 2017 Category: International Medicine & Public Health Source Type: research

Exosomal microRNAs as potential circulating biomarkers in gastrointestinal tract cancers: a systematic review protocol
DiscussionThe analysis of circulating exosomal miRNA profiles provides attractive screening and non-invasive diagnostic tools for the majority of solid tumors including GI cancers. There is limited information regarding the relationship between serum exosomal miRNA profiles and the pathological condition of patients with different GI cancers. Since there is no specific biomarker for GI cancers, we aim to suggest a number of circulating exosomal miRNA candidates as potential multifaceted GI cancer biomarkers for clinical utility.Systematic review registrationPROSPEROCRD42017057129 (Source: Systematic Reviews)
Source: Systematic Reviews - November 17, 2017 Category: International Medicine & Public Health Source Type: research

Mapping evidence on the distribution of human papillomavirus-related cancers in sub-Saharan Africa: scoping review protocol
DiscussionWe anticipate finding relevant literature on the distribution of HPV-related cancers in sub-Saharan Africa. The study findings will help reveal research gaps to guide future research.Systematic review registrationPROSPERO CRD42017062403. (Source: Systematic Reviews)
Source: Systematic Reviews - November 17, 2017 Category: International Medicine & Public Health Source Type: research

Prevalence and prognosis of acutely ill patients with organ failure at arrival to hospital: protocol for a systematic review
DiscussionThis review will summarize and analyze studies of prevalence and prognosis of acutely ill patients, with organ failure at arrival to hospital, assist ED physicians assessing the risk of organ failure in unselected patients, and guide recommendations for further research.Systematic review registrationPROSPERO CRD42017060871 (Source: Systematic Reviews)
Source: Systematic Reviews - November 15, 2017 Category: International Medicine & Public Health Source Type: research

Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol
DiscussionThis systematic review of preclinical evidence will provide a summary of the efficacy and safety of MSCs in animal models of MI. The results will help determine whether sufficient evidence exists to conduct a clinical trial in humans and inform its design. (Source: Systematic Reviews)
Source: Systematic Reviews - November 7, 2017 Category: International Medicine & Public Health Source Type: research

Effectiveness of interventions during NICU hospitalization on the neurodevelopment of preterm infants: a systematic review protocol
DiscussionThe results of this systematic review will highlight which interventions are effective for promoting preterm infants ’ neurodevelopment during NICU hospitalization and will contribute to the body of knowledge in neonatal care by providing guidance for NICU clinical practice and research.Systematic review registrationPROSPEROCRD42017047072 (Source: Systematic Reviews)
Source: Systematic Reviews - November 3, 2017 Category: International Medicine & Public Health Source Type: research

The role of psychosocial stress in the development of chronic musculoskeletal pain disorders: protocol for a systematic review and meta-analysis
DiscussionTo our knowledge, this review will be the first to systematically explore the available evidence on the aetiological role of psychosocial stress for the development of chronic musculoskeletal pain disorders. This review has the capacity to inform clinical practice on the importance of an early identification and, consequently, treatment of individuals who present with acute musculoskeletal disorders accompanied by a high level of stress.Systematic review registrationPROSPEROCRD42017059949 (Source: Systematic Reviews)
Source: Systematic Reviews - November 3, 2017 Category: International Medicine & Public Health Source Type: research

Reliability of measurements of the fractured clavicle: a systematic review
ConclusionNo definite conclusions could be drawn. In order to optimize future studies and the realization of comparable results, more research is necessary to identify a standardized method of imaging and measuring.Level of Evidence III. (Source: Systematic Reviews)
Source: Systematic Reviews - November 3, 2017 Category: International Medicine & Public Health Source Type: research

The macro-economic determinants of health and health inequalities —umbrella review protocol
DiscussionOur umbrella review protocol provides a robust method to systematically appraise the evidence in this field, using new conceptual models derived specifically to address the study question. This will yield important information for policymakers, practitioners and researchers at the local, national and international level. It will also help set the future research agenda in this field and guide the development of interventions.Systematic review registrationThis umbrella review protocol has been registered with PROSPEROCRD42017068357. (Source: Systematic Reviews)
Source: Systematic Reviews - November 3, 2017 Category: International Medicine & Public Health Source Type: research

Putting research in place: an innovative approach to providing contextualized evidence synthesis for decision makers
ConclusionsBy asking the health system to identify its own priorities and to participate directly in the research process, CHRSP fully integrates KT among researchers and knowledge users in healthcare in Newfoundland and Labrador. This high level of decision-maker buy-in has resulted in a corresponding level of uptake. CHRSP studies have directly informed a number of policy and practice directions, including the design of youth residential treatment centers, a provincial policy on single-use medical devices, and most recently, the opening of the province ’s first Acute Care for the Elderly hospital unit. (Source: Systematic Reviews)
Source: Systematic Reviews - November 2, 2017 Category: International Medicine & Public Health Source Type: research

Methodological quality and transparency of clinical practice guidelines for the pharmacological treatment of non-communicable diseases using the AGREE II instrument: a systematic review protocol
DiscussionThe AGREE II instrument will be applied to evaluate the quality of CPGs and contribute to enhance the discussion and development of guidelines of high quality. The findings will be submitted for publication in high-impact, peer-reviewed scientific journals and will also be disseminated at international conferences.Systematic review registrationPROSPEROCRD42016043364 (Source: Systematic Reviews)
Source: Systematic Reviews - November 2, 2017 Category: International Medicine & Public Health Source Type: research

Family resilience and adaptive coping in children with juvenile idiopathic arthritis: protocol for a systematic review
The objective is to determine which resilience processes are associated with a favourable quality of life in terms of academic, communication, emotional, interpersonal, physical, psychological, and social well-being in families of children with chronic pain associated with JIA.Methods/designThis systematic review will be conducted and reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement and the PRESS (Peer Review of Electronic Search Strategies) guideline.Longitudinal, cross-sectional, and treatment studies written in English will be included, as will grey literature ...
Source: Systematic Reviews - November 2, 2017 Category: International Medicine & Public Health Source Type: research

Mobile tablet-based therapies following stroke: a systematic scoping review protocol of attempted interventions and the challenges encountered
DiscussionTrends in MTBT feasibility and common challenges will be discussed to summarize major findings and highlight research gaps. Solutions to common challenges experienced by intervention participants and study staff will be proposed. Implications for the conduct of randomized clinical trials of MTBT efficacy and the appropriateness of a systematic review and meta-analysis of completed trials will be discussed.Systematic review registrationuO Research (http://hdl.handle.net/10393/35696). (Source: Systematic Reviews)
Source: Systematic Reviews - November 2, 2017 Category: International Medicine & Public Health Source Type: research

Effectiveness of real-time polymerase chain reaction assay for the detection of Mycobacterium tuberculosis in pathological samples: a systematic review and meta-analysis
ConclusionsRT-PCR assay demonstrated a high degree of sensitivity for pulmonary TB and good sensitivity for extra-pulmonary TB. It indicated a high degree of specificity for ruling in TB infection from sampling regimes. This was acceptable, but may better as a rule out add-on diagnostic test. RT-PCR assays demonstrate both a high degree of sensitivity in pulmonary samples and rapidity of detection of TB which is an important factor in achieving effective global control and for patient management in terms of initiating early and appropriate anti-tubercular therapy.Systematic review registrationPROSPEROCRD42015027534. (Sourc...
Source: Systematic Reviews - October 25, 2017 Category: International Medicine & Public Health Source Type: research

Understanding the experience of initiating community-based physical activity and social support by people with serious mental illness: a systematic review using a meta-ethnographic approach
DiscussionThis systematic review is expected to provide new insights into the experience of community-based group physical activity initiation for adults who have a serious mental illness to inform person-centred improvements to the management of serious mental illness through physical activity.Systematic review registrationThe protocol has been registered on the International Prospective Register of Systematic Reviews (PROSPERO) on 22/03/2017; (registration numberCRD42017059948). (Source: Systematic Reviews)
Source: Systematic Reviews - October 25, 2017 Category: International Medicine & Public Health Source Type: research

The relationship between childhood body weight and dental caries experience: an umbrella systematic review protocol
DiscussionThe final umbrella review aims to aggregate the available evidence in order to provide a summary for policymakers and to inform healthcare interventions.Systematic review registrationPROSPEROCRD42016047304 (Source: Systematic Reviews)
Source: Systematic Reviews - October 25, 2017 Category: International Medicine & Public Health Source Type: research

Availability and performance of image/video-based vital signs monitoring methods: a systematic review protocol
DiscussionTo the best of our knowledge, this is the first systematic review of image-based non-contact methods of vital signs monitoring. Synthesis of currently available technology will facilitate future research in this highly topical area.Systematic review registrationPROSPEROCRD42016029167 (Source: Systematic Reviews)
Source: Systematic Reviews - October 25, 2017 Category: International Medicine & Public Health Source Type: research

Diabetes-related information-seeking behaviour: a systematic review
ConclusionThe systematic review provides a valuable overview of available knowledge on the information-seeking behaviour of people with diabetes mellitus, although there are only a few studies. There was a high heterogeneity regarding the research question, design, methods and participants. Although the Internet is often used to seek information, health professionals still play an important role in supporting their patients ’ information-seeking behaviour. Specific needs of people with diabetes must be taken into consideration.Systematic review registrationPROSPEROCRD42016037312 (Source: Systematic Reviews)
Source: Systematic Reviews - October 24, 2017 Category: International Medicine & Public Health Source Type: research

Interventions for acute stroke management in Africa: a systematic review of the evidence
ConclusionEvidence from this review confirms the widespread assertion of low applicability and uptake of evidence-based acute stroke care in LMICs. Despite the limited eligible studies, the overall positive patient outcomes following such interventions demonstrate the applicability and value of evidence-based acute stroke care interventions in Africa. Health policy attention is thus required to ensure widespread applicability of such interventions for improved patients ’ outcomes. The review findings also emphasises the need for further research to unravel the reasons for low uptake.Systematic review registrationPROS...
Source: Systematic Reviews - October 24, 2017 Category: International Medicine & Public Health Source Type: research

Effectiveness of behavioral change techniques employed in eHealth interventions designed to improve glycemic control in persons with poorly controlled type 2 diabetes: a systematic review and meta-analysis protocol
DiscussionThis systematic review is one of the firsts to appraise the effectiveness of eHealth interventions employing BCTs which aimed at improving glycemic control in persons with poorly controlled T2DM. The review will aggregate the effect sizes of BCTs on HbA1c levels. The results may inform future eHealth interventions targeting poorly controlled T2DM populations.Systematic review registrationPROSPERO CRD42016049940 (Source: Systematic Reviews)
Source: Systematic Reviews - October 24, 2017 Category: International Medicine & Public Health Source Type: research

Authors ’ response to comments from Nachman KE et al.
AbstractAuthors ’ response to comments letter to the editor from Nachman KE et al. (Source: Systematic Reviews)
Source: Systematic Reviews - October 23, 2017 Category: International Medicine & Public Health Source Type: research

Use of social network analysis methods to study professional advice and performance among healthcare providers: a systematic review
ConclusionNetwork methods are underutilized for the purposes of understanding professional communication and performance among healthcare providers. The paucity of articles meeting our search criteria, lack of studies in middle- and low-income contexts, limited number in non-tertiary settings, and few longitudinal, experimental designs, or network interventions present clear research gaps.Systematic review registrationPROSPEROCRD42015019328 (Source: Systematic Reviews)
Source: Systematic Reviews - October 23, 2017 Category: International Medicine & Public Health Source Type: research

Exploring the clinically orientated roles of the general practice receptionist: a systematic review protocol
DiscussionThe review will explore existing research covering the clinically orientated roles of the GP receptionist. The findings of the review will be important for healthcare professionals and academics working within primary healthcare. It will highlight and for the first time synthesise research relating to the complex and essential work of the GP receptionist. Our findings will inform the direction and focus of further research, as gaps in the knowledge base will be uncovered.Systematic review registrationPROSPERO registration no:CRD42016048957. (Source: Systematic Reviews)
Source: Systematic Reviews - October 23, 2017 Category: International Medicine & Public Health Source Type: research

A systematic review protocol on the effectiveness of therapeutic exercises utilised by physiotherapists to improve function in patients with burns
DiscussionBurns may have a long-lasting impact on both psychological and physical functioning and thus it is important to identify and evaluate the effects of current and past aerobic and strength exercises on patients with burns. By identifying the characteristics of effective exercise programmes, guidelines can be suggested for developing intervention programmes aimed at improving the function of patients with burns. The safety and precautions of exercise regimes and the optimal frequency, duration, time and intensity will also be examined to inform further intervention.Systematic review registrationPROSPEROCDR4201604837...
Source: Systematic Reviews - October 23, 2017 Category: International Medicine & Public Health Source Type: research

Costs related to cardiac arrest management: a systematic review protocol
DiscussionThis review will provide an estimate of costs related to cardiac arrest management according to the different components of such a management as well as total costs.Systematic review registrationInternational Prospective Register of Systematic Reviews PROSPEROCRD42016046993 (Source: Systematic Reviews)
Source: Systematic Reviews - October 17, 2017 Category: International Medicine & Public Health Source Type: research

SEED: a tool for disseminating systematic review data into Wikipedia
AbstractWikipedia, the free-content online encyclopaedia, contains many heavily accessed pages relating to healthcare. Cochrane systematic reviews contain much high-grade evidence but dissemination into Wikipedia has been slow. New skills are needed to both translate and relocate data from Cochrane reviews to implant into Wikipedia pages. This letter introduces a programme to greatly simplify the process of disseminating the summary of findings of Cochrane reviews into Wikipedia pages. (Source: Systematic Reviews)
Source: Systematic Reviews - October 17, 2017 Category: International Medicine & Public Health Source Type: research

A proposed framework for developing quality assessment tools
ConclusionsWe recommend that anyone who would like to develop a new quality assessment tool follow the stages outlined in this paper. We hope that our proposed framework will increase the number of tools developed using robust methods. (Source: Systematic Reviews)
Source: Systematic Reviews - October 17, 2017 Category: International Medicine & Public Health Source Type: research

Olfactive stimulation interventions for managing procedural pain in preterm and full-term neonates: a systematic review protocol
The objective of this systematic review is to evaluate the effect of olfactive stimulation intervention on the pain response of preterm and full-term neonates during painful procedures.MethodsAn electronic search will be conducted in various databases such as PubMed (1946 to date), MEDLINE (1946 to date), CINAHL (1981 to date), Embase (1947 to date), PsycINFO (1806 to date), Web of Science (1945 to date), CENTRAL and Scopus (1960 to date), and Proquest, without restriction for the year of publication. Only studies published in English or French will be included. The search will be conducted using the following three concep...
Source: Systematic Reviews - October 17, 2017 Category: International Medicine & Public Health Source Type: research

High-flow oxygen via nasal cannulae in patients with acute hypoxemic respiratory failure: a systematic review and meta-analysis
ConclusionsIn patients with acute hypoxemic respiratory failure HFNC was not associated with a difference in mortality compared to NIV or standard oxygen. Secondary outcomes including dyspnea, tolerance, and safety were not systematically reported. Residual heterogeneity and variable reporting of secondary outcomes limit the conclusions that can be made in this review. Prospective trials designed to evaluate the efficacy and safety of HFNC in patients with acute hypoxemic respiratory failure are required. (Source: Systematic Reviews)
Source: Systematic Reviews - October 16, 2017 Category: International Medicine & Public Health Source Type: research

Ventriculoperitoneal shunt insertion for hydrocephalus in human immunodeficiency virus-infected adults: a systematic review and meta-analysis protocol
This study will generate a comprehensive review of VPS in HIV-infected patients for publication. The primary outcome of meta-analysis is 12-month survival. If only low-quality, heterogeneous studies are available, this study will demonstrate this deficiency and will be of value in justifying and aiding the design of future studies.Systematic review registrationPROSPERO CRD42016052239 (Source: Systematic Reviews)
Source: Systematic Reviews - October 16, 2017 Category: International Medicine & Public Health Source Type: research

Renal manifestations of HIV during the antiretroviral era in South Africa: a systematic scoping review
ConclusionThe findings of the review have implications to the recently adopted ‘test and treat’ approach to HIV prevention and management.Systematic review registrationPROSPEROCRD42016039270 (Source: Systematic Reviews)
Source: Systematic Reviews - October 13, 2017 Category: International Medicine & Public Health Source Type: research