School factors related to the emotional wellbeing and resettlement outcomes of students from refugee backgrounds: protocol for a systematic review
DiscussionGiven the centrality of school in the daily lives of resettled refugee children, it is vital to assess the impact of school climate on the psychosocial wellbeing and resettlement trajectories of this population. This review will identify evidence-based school factors which support good mental health and resettlement outcomes for refugee students and make recommendations for translation of this knowledge into the school environment.Systematic review registrationPROSPERO CRD42017077570 (Source: Systematic Reviews)
Source: Systematic Reviews - April 30, 2019 Category: International Medicine & Public Health Source Type: research

Correction to: Systematic review and meta-analysis of diagnostic accuracy of detection of any level of diabetic retinopathy using digital retinal imaging
Following publication of the original article [1], the authors reported an error in Fig.  4 in the PDF version. Figure 4 is the duplicate image of Fig. 3 and the correct figure is missing. The authors would like to apologize for this error. The correct figure is shown below. (Source: Systematic Reviews)
Source: Systematic Reviews - April 30, 2019 Category: International Medicine & Public Health Source Type: research

The effects of aerobic, resistance, and meditative movement exercise on sleep in individuals with depression: protocol for a systematic review and network meta-analysis
DiscussionThis systematic review and network meta-analysis will provide a synthesis of the currently available evidence concerning the effects of aerobic, resistance, and meditative movement exercises on sleep in patients with unipolar depression. Thereby, we hope to accelerate the consolidation of evidence and inform decision-makers on potential benefits and harms.Systematic review registrationThe protocol has been registered at the International Prospective Register of Systematic Reviews (PROSPERO; registration number: CRD42019115705). (Source: Systematic Reviews)
Source: Systematic Reviews - April 26, 2019 Category: International Medicine & Public Health Source Type: research

Examining the mental health outcomes of peer-led school-based interventions on young people aged between 4 and 18  years old: a systematic review protocol
DiscussionThis systematic review will be the first to synthesise the global evidence on the mental health outcomes of peer-led interventions for children and adolescents in a school setting. It will analyse the available data in order to understand the role of these interventions in schools, inform future developers of peer support programmes and identify gaps in current research. This review will be of value to policy makers, health and education services, researchers and those involved in delivering peer support initiatives.Systematic review registrationPROSPERO CRD42018116243 (Source: Systematic Reviews)
Source: Systematic Reviews - April 26, 2019 Category: International Medicine & Public Health Source Type: research

Neonatal mortality in Ethiopia: a protocol for systematic review and meta-analysis
DiscussionThe result from this systematic review will inform and guide health policy planners and researchers on the burden, causes, and determinants of neonatal mortality in Ethiopia. To our knowledge, this is the first systematic review in Ethiopia. We will synthesise the findings to generate up-to-date knowledge on neonatal mortality in Ethiopia.Systematic review registrationPROSPERO-CRD42018099663 (Source: Systematic Reviews)
Source: Systematic Reviews - April 26, 2019 Category: International Medicine & Public Health Source Type: research

Communication strategies for rare cancers: a systematic review protocol
DiscussionDespite the broad topic and width of study type that will be considered, this review hopes to provide a reflective summary of the communication strategies available for people living with and working with rare cancer. It aims to reveal any gaps in the resources available, to contribute to the long-term improvement of diagnosis and management of rare cancers.Systematic review registrationPROSPERO CRD42018099784 (Source: Systematic Reviews)
Source: Systematic Reviews - April 23, 2019 Category: International Medicine & Public Health Source Type: research

Interventions for improved diabetes control and self-management among those experiencing homelessness: protocol for a mixed methods scoping review
DiscussionThose experiencing homelessness who also have diabetes often struggle to manage their chronic condition. When care is tailored to suit their needs, it is feasible that outcomes may be improved. By collating and synthesizing information from diverse organizations and jurisdictions, we hope to facilitate the sharing of knowledge with others who wish to provide this type of care. (Source: Systematic Reviews)
Source: Systematic Reviews - April 22, 2019 Category: International Medicine & Public Health Source Type: research

Effects of aerobic exercise on pain and disability in patients with non-specific chronic low back pain: a systematic review protocol
DiscussionThis systematic review will provide a synthesis of current evidence on the effects of aerobic exercise in patients with chronic low back pain on pain and disability outcomes. This information can help healthcare professionals in decision-making related to the use of aerobic exercise in patients with low back pain.Following the guidelines, this systematic review protocol was registered on the Prospective International Register of Systematic Reviews (PROSPERO) number CRD42017071945. (Source: Systematic Reviews)
Source: Systematic Reviews - April 22, 2019 Category: International Medicine & Public Health Source Type: research

Understanding patient engagement in health system decision-making: a co-designed scoping review
ConclusionsThe results of this scoping review demonstrate that an evidence base around programs to advance patient engagement is largely absent. An opportunity exists for further research to identify strategies and measures to support patient engagement in healthcare decision-making. (Source: Systematic Reviews)
Source: Systematic Reviews - April 18, 2019 Category: International Medicine & Public Health Source Type: research

Communication strategies in the prevention of type 2 and gestational diabetes in vulnerable groups: protocol for a scoping review
DiscussionThe results will be used to inform the National education and communication strategy on diabetes mellitus in Germany. In particular, the results will be discussed in focus groups of experts to develop recommendations for communication strategies.Systematic review registrationPROSPERO does not register scoping reviews. (Source: Systematic Reviews)
Source: Systematic Reviews - April 18, 2019 Category: International Medicine & Public Health Source Type: research

Direct oral anticoagulants in treatment of cerebral venous thrombosis: a systematic review protocol
DiscussionCurrent guidelines in the treatment of cerebral vein thrombosis dating back to 2011 from the American Heart Association/American Stroke Association endorse the utility of anticoagulation for the treatment of cerebral vein thrombosis; however, they did not support the use of direct oral anticoagulants. Updated guidelines from the European Stroke Organization, endorsed by the European Academy of Neurology in 2017, also refute utilization of direct oral anticoagulants due to a lack of evidence. There have been nearly 10  years of experience with direct oral anticoagulants in the treatment of venous thrombosis...
Source: Systematic Reviews - April 18, 2019 Category: International Medicine & Public Health Source Type: research

Individual patient data network meta-analysis using either restricted mean survival time difference or hazard ratios: is there a difference? A case study on locoregionally advanced nasopharyngeal carcinomas
ConclusionThe use of either HR or rmstD impacts the results of NMA. Given the sensitivity of HR to non-proportional hazards, this finding could have implications in terms of meta-analysis methodology. (Source: Systematic Reviews)
Source: Systematic Reviews - April 15, 2019 Category: International Medicine & Public Health Source Type: research

Influence of adjuvant antibiotics on fistula formation following incision and drainage of anorectal abscesses: a systematic review protocol
The objective of this review is to summarize the available evidence on the role of antibiotics following I&D of anorectal abscesses on fistula formation. Secondary objectives include determining if antibiotics are associated with morbidity, repeat presentation to the emergency department, and requirement for reoperation.Methods/designMEDLINE, EMBASE, CINAHL, Cochrane Central Registry of Controlled Trials,http://apps.who.int/trialsearch, andclinicaltrials.gov will be searched to identify published and ongoing unpublished interventional and observational studies evaluating the role of antibiotics post I&D on the inci...
Source: Systematic Reviews - April 15, 2019 Category: International Medicine & Public Health Source Type: research

Searching for health equity: validation of a search filter for ethnic and socioeconomic inequalities in transport
ConclusionsThe validated search strategy derived in this study facilitates the conduct of systematic reviews and other literature searches investigating whether the effects of interventions differ by ethnicity or socio-economic status and may be further developed in future for other equity-focused searches and reviews. (Source: Systematic Reviews)
Source: Systematic Reviews - April 11, 2019 Category: International Medicine & Public Health Source Type: research

Differential methylation in rare ophthalmic disorders: a systematic review protocol
DiscussionThis systematic review will enable us to identify if differential methylation can be used to characterise rare ophthalmic disease, which could have crucial implications for improving the accuracy and speed of diagnosis, identifying novel therapeutic targets to reduce or prevent vision loss and overall improving understanding of rare ophthalmic disease.Systematic review registrationPROSPERO CRD42018094231 (Source: Systematic Reviews)
Source: Systematic Reviews - April 10, 2019 Category: International Medicine & Public Health Source Type: research

Patient and family-initiated escalation of care: a qualitative systematic review protocol
DiscussionPatient- and family-initiated escalation of care schemes have been developed and implemented in several countries including the United  States, the United Kingdom and Australia, but there is limited evidence regarding patients’ or families’ perceptions of deterioration or the barriers and facilitators to using these schemes in practice, particularly in acute adult areas. This systematic review will provide evidence for the de velopment of a patient and family escalation of care scheme that can be tested in a feasibility study.Systematic review registrationPROSPEROCRD42018106952 (Source: Systematic Reviews)
Source: Systematic Reviews - April 9, 2019 Category: International Medicine & Public Health Source Type: research

The impact of income support systems on healthcare quality and functional capacity in workers with low back pain: a realist review protocol
DiscussionIncome support and healthcare systems are highly complex and fluid programmes. At the intersection between these systems are those with low back pain. By using realist review methods, we will provide explanatory rather than judgemental findings. The resulting multi-dimensional and contextual understanding of the impact of income support systems on important low back pain outcomes will provide valuable insight for future income support and healthcare policy development. (Source: Systematic Reviews)
Source: Systematic Reviews - April 9, 2019 Category: International Medicine & Public Health Source Type: research

Risk of bias judgements and strength of conclusions in meta-evidence from the Cochrane Colorectal Cancer Group
Conclusions were categorized as informing clinical practice (I) or not (N). Both I and N categories were divided into firm (F) or tempered (T) based on the definitiveness of their language. ROB judgements were aggregated. Reviews were classed as Medical (M), Surgical (S), Medical& Surgical (MS) or Other (O) based on their intervention, with O reviews then excluded. Data were analyzed in SPSS.ResultsNinety-five reviews were included, covering 1892 studies. Sixty-two percent (n = 59/95) informed clinical practice (I). Thirty-eight percent (n = 36/95) did not inform clinical practice (N). Of th...
Source: Systematic Reviews - April 8, 2019 Category: International Medicine & Public Health Source Type: research

Association between harm reduction strategies and healthcare utilization in patients on long-term prescribed opioid therapy presenting to acute healthcare settings: a protocol for a systematic review and meta-analysis
This study will better characterize harm reduction strategies for patients on long-term prescribed opioids presenting to acute healthcare settings. It will also add new knowledge and generate greater understanding of key knowledge gaps of the long-term prescribed opioid use and its impact on healthcare utilization.Systematic review registrationCRD42018088962. (Source: Systematic Reviews)
Source: Systematic Reviews - April 5, 2019 Category: International Medicine & Public Health Source Type: research

Seeking adverse effects in systematic reviews of orthodontic interventions: protocol for a cross-sectional study
This study will assess whether adverse effects were sought and whether findings related to adverse effects were reported in systematic reviews of orthodontic interventions in the five leading orthodontic journals and in the Cochrane Database of Systematic Reviews.MethodsSystematic reviews of clinical orthodontic interventions published between 01 August 2009 and 31 July 2019 in the five leading orthodontic journals and in the Cochrane Database will be included. Empty reviews will be excluded. The reporting of outcomes on adverse effects will not determine eligibility, i.e., reviews will not be excluded, because they did no...
Source: Systematic Reviews - April 5, 2019 Category: International Medicine & Public Health Source Type: research

Protocol for a systematic review, meta-analysis, and trial sequential analysis of clinical outcomes following accelerated versus conventional corneal collagen cross-linking for corneal ectasia
DiscussionThis review will provide a comprehensive evaluation of the evidence on accelerated and conventional CXL approaches and serve to inform clinical practice, medical device design, and future research. Evaluating variations of the CXL protocol aimed at reducing treatment duration is of critical importance and a prerequisite to expanding treatment availability to more patients.Systematic review registrationPROSPERO CRD42018104151 (Source: Systematic Reviews)
Source: Systematic Reviews - April 4, 2019 Category: International Medicine & Public Health Source Type: research

Addressing preconception behaviour change through mobile phone apps: a protocol for a systematic review and meta-analysis
DiscussionThis systematic review is the first to assess the effects of preconception mobile phone app behaviour change and educational interventions in improving future pregnancy and maternal and child outcomes, in women of reproductive age.Systematic review registrationPROSPERO 2017:CRD42017065903. (Source: Systematic Reviews)
Source: Systematic Reviews - April 4, 2019 Category: International Medicine & Public Health Source Type: research

Predicting repeated self-harm or suicide in adolescents and young adults using risk assessment scales/tools: a systematic review protocol
DiscussionThis systematic review will be the first to explore the use of assessment scales/tools in an adolescent population and will help to inform current practice regarding scales/tools with higher predictive ability. There is currently no evidence specifically for this population and a clear need with a high prevalence of self-harm and suicide in adolescents. Additionally, this review will help guide future research into suicide and self-harm prediction and prevention.Systematic review registrationPROSPEROCRD42017058686 (Source: Systematic Reviews)
Source: Systematic Reviews - April 4, 2019 Category: International Medicine & Public Health Source Type: research

Discharge communication practices in pediatric emergency care: a systematic review and narrative synthesis
ConclusionExisting literature examining discharge communication in pediatric emergency care varies widely. A theory-based approach to intervention design is needed to improve our understanding regarding discharge communication practice. Strengthening discharge communication in a pediatric emergency context presents a significant opportunity for improving parent comprehension and health outcomes for children.Systematic review registrationPROSPERO registration number: CRD42014007106. (Source: Systematic Reviews)
Source: Systematic Reviews - April 3, 2019 Category: International Medicine & Public Health Source Type: research

Protocol for a systematic review of time to antibiotics (TTA) in patients with fever and neutropenia during chemotherapy for cancer (FN) and interventions aiming to reduce TTA
This study aims to evaluate the association between TTA and patient-important clinical outcomes. Additionally, it will identify, critically appraise, and synthesise information on performed interventions and its effect to reduce TTA as a way of gaining insight into the potential use of these approaches. This will provide better knowledge for an adjusted treatment approach of FN.Systematic review registrationPROSPERO [CRD42018092948] (Source: Systematic Reviews)
Source: Systematic Reviews - April 3, 2019 Category: International Medicine & Public Health Source Type: research

Interventions to improve emergency department use for mental health reasons: protocol for a mixed-methods systematic review
DiscussionUsing a combined systematic review methodology and integrated knowledge translation plan, the project will provide decision makers with concrete evidence to support the implementation and evaluation of interventions to improve emergency department use for mental health reasons. These interventions reflect widespread priorities in the area of mental health care.Systematic review registrationPROSPEROCRD42018087430 (Source: Systematic Reviews)
Source: Systematic Reviews - April 3, 2019 Category: International Medicine & Public Health Source Type: research

Interventions for reducing and/or controlling domestic violence among pregnant women in low- and middle-income countries: a systematic review
DiscussionThis review attempted to address the knowledge gap by collating evidence on interventions aimed at addressing DV among pregnant women in LMICs. The development of a ToC was critical in understanding how certain activities led to the desired outcomes. This ToC can guide the design of future research and development of practice guidelines. The participatory involvement of the stakeholders is recommended to refine the current ToC to support its further development for practice.Systematic review registrationPROSPERO,CRD42017073938 (Source: Systematic Reviews)
Source: Systematic Reviews - April 2, 2019 Category: International Medicine & Public Health Source Type: research

The association between diabetes and age at the onset of menopause: a systematic review protocol
AbstractBackgroundAge at the onset of menopause is the most important determinant of women ’s future health outcomes. While the basic mechanisms contributing to the onset of menopause are still not fully understood, age at menopause depends on a complex set of various factors. In this regard, the effects of diabetes (DM I/II) on the age at the onset of menopause have received little att ention.Methods and analysisElectronic databases including PubMed/MEDLINE, Web of Science, Scopus, EMBASE, and Google Scholar will be searched for articles published during January 2000 to August 2018 and containing combinations of rel...
Source: Systematic Reviews - April 2, 2019 Category: International Medicine & Public Health Source Type: research

Well siblings ’ experiences of living with a child following a traumatic brain injury: a systematic review protocol
DiscussionIt is anticipated that the findings of the proposed review will be of interest to health and social care professionals, particularly those working in units where children have suffered TBIs, their well siblings, and families. The aim is to identify well siblings ’ experiences which can inform enhanced care delivery to the families of children following a TBI. The findings of this review will provide evidence to aid professionals with the assessment of siblings’ needs to enhance their sense of self within the family unit. Future directions, in addition t o potential limitations of the approach, will be...
Source: Systematic Reviews - April 2, 2019 Category: International Medicine & Public Health Source Type: research

Patient prioritization tools and their effectiveness in non-emergency healthcare services: a systematic review protocol
DiscussionThis systematic review will provide much-needed knowledge regarding patient prioritization tools. The results will benefit clinicians, decision-makers, and researchers by giving them a better understanding of the methods used to prioritize patients in clinical settings.Systematic review registrationPROSPEROCRD42018107205 (Source: Systematic Reviews)
Source: Systematic Reviews - March 30, 2019 Category: International Medicine & Public Health Source Type: research

Feasibility, acceptability, and effectiveness of young people-specific, integrated out-of-hospital services: a protocol for a systematic review
DiscussionThis review aims to provide comprehensive evidence regarding young people-specific integrated out-of-hospital health services. Such rigorously evaluated evidence will be useful for policy makers and health professionals to design and select health services for this group. This review will also identify any evidence gaps in young people-specific integrated health services evaluation.Systematic review registrationPROSPEROCRD42017068836 (Source: Systematic Reviews)
Source: Systematic Reviews - March 28, 2019 Category: International Medicine & Public Health Source Type: research

Trends in maternal and neonatal mortality in South Africa: a systematic review
ConclusionEstimates from both global metrics and institutional reporting, although widely divergent, indicate South Africa has not achieved MDG 4a and 5a goals but made a significant progress in reducing maternal and neonatal mortality. To obtain more accurate estimates, there is a need for applying additional estimation techniques which utilise available multiple data sources to correct for underreporting of these outcomes, perhaps the capture-recapture method.Systematic review registrationPROSPERO CRD42016042769 (Source: Systematic Reviews)
Source: Systematic Reviews - March 27, 2019 Category: International Medicine & Public Health Source Type: research

Cost-effectiveness of cannabinoids for pediatric drug-resistant epilepsy: protocol for a systematic review of economic evaluations
DiscussionDrug-resistant epilepsy in children is associated with important costs to the healthcare system, and decision-makers require high-quality evidence on which to base reimbursement decisions. The results of this review will be useful to both decision-makers considering the decision problem of whether to reimburse cannabis-based products through public formularies and to analysts conducting studies in this area.Systematic review registrationPROSPERO no.:CRD42018099591. (Source: Systematic Reviews)
Source: Systematic Reviews - March 27, 2019 Category: International Medicine & Public Health Source Type: research

Comparing options for women seeking permanent contraception in high-resource countries: a protocol for a systematic review
DiscussionClinicians and their patients seeking permanent contraception have several options, yet we were unable to find a systematic review or decision support tool helping to facilitate shared decision-making. This systematic review can inform patients, providers, and health policy decision-makers about which options of permanent contraception will meet different reproductive goals according to various outcomes, which can lead to better health, social, economic, and mental well-being for reproductive age women. This can also aid our understanding of resulting costs to the health care system.Systematic review registration...
Source: Systematic Reviews - March 26, 2019 Category: International Medicine & Public Health Source Type: research

Serum 25-hydroxyvitamin D levels and mortality risk in patients with liver cirrhosis: a protocol for a systematic review and meta-analysis of observational studies
DiscussionThe study will assess the effects of serum 25-hydroxyvitamin D concentrations on mortality in patients with liver cirrhosis. The results will be published in a high-quality peer-reviewed journal.Systematic review registrationProsperoCRD42016052007. (Source: Systematic Reviews)
Source: Systematic Reviews - March 23, 2019 Category: International Medicine & Public Health Source Type: research

Prevalence of suicidal ideation, suicidal attempt and completed suicide in Ethiopia: a systematic review and meta-analysis protocol
DiscussionThis systematic review and meta-analysis aims to explore the available epidemiological evidences about suicidal ideation, suicidal attempt, and completed suicide. The final results of this review will be submitted for publication in a peer-reviewed journal and presented at conferences. The review of the results will help to raise awareness about the burden of suicidal ideation, suicidal attempt, and completed suicide in Ethiopia.Systematic review registrationPROSPEROCRD42018112836 (Source: Systematic Reviews)
Source: Systematic Reviews - March 22, 2019 Category: International Medicine & Public Health Source Type: research

Network meta-analysis of randomised trials of pharmacological, psychotherapeutic, exercise and collaborative care interventions for depressive symptoms in patients with coronary artery disease: hybrid systematic review of systematic reviews protocol
DiscussionThe present review will address uncertainties about the evidence in terms of depression management in CAD and may allow for a ranking of treatments, including providing important information for future research efforts.Systematic review registrationPROSPEROCRD42018108293 (Source: Systematic Reviews)
Source: Systematic Reviews - March 16, 2019 Category: International Medicine & Public Health Source Type: research

Editorial: Systematic review automation thematic series
(Source: Systematic Reviews)
Source: Systematic Reviews - March 11, 2019 Category: International Medicine & Public Health Source Type: research

Traditional knowledge-based lifestyle interventions in the prevention of obesity and type 2 diabetes in Indigenous children in Canada: a systematic review protocol
DiscussionThis review will provide a summary of current interventions to prevent obesity and T2DM in Indigenous children in Canada and help determine the gaps in the literature so that interventions can be developed to control the surge in pediatric T2DM in Indigenous communities.Systematic review registrationPROSPERO CRD42017072781 (Source: Systematic Reviews)
Source: Systematic Reviews - March 6, 2019 Category: International Medicine & Public Health Source Type: research

Effects of training and support programs for leaders of illness-based support groups: commentary and updated evidence
ConclusionsOur systematic review update found that there is presently insufficient evidence on the effectiveness of training and support programs for peer leaders of disease-based support groups, highlighting the need for well-designed and rigorously conducted RCTs to examine the effects of training for peer leaders of support groups, especially in a rare disease context. The Scleroderma Patient-centered Intervention Network ’s trial of the Scleroderma Support group Leader EDucation Program will serve as such a trial.Systematic review registrationPROSPEROCRD42018096369 (Source: Systematic Reviews)
Source: Systematic Reviews - March 5, 2019 Category: International Medicine & Public Health Source Type: research

Effects of antiretroviral therapy in HIV-positive adults on new HIV infections among young women: a systematic review protocol
DiscussionTo our knowledge, this is the first systematic review to look at the impact of ART use among adults on HIV incidence in young women. The results of this review will be used in a modeling study to simulate the effects of using ART as an effective tool to prevent sexual transmission of HIV to young women. Our findings will inform the treatment-as-prevention (TasP) strategy to reduce new HIV infections among young women.Systematic review registrationThe systematic review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO), registration numberCRD42018099174. (Source: Systematic Reviews)
Source: Systematic Reviews - March 5, 2019 Category: International Medicine & Public Health Source Type: research

Social marketing including financial incentive programs at worksite cafeterias for preventing obesity: a systematic review
ConclusionsLack of evidence made it difficult to draw any conclusions. In future surveys, it will be necessary to conduct interventions focusing only on financial incentive intervention versus no intervention in order to determine whether the incentive strategy has a clear impact.Systematic review registrationPROSPERO CRD4201401056 (Source: Systematic Reviews)
Source: Systematic Reviews - February 28, 2019 Category: International Medicine & Public Health Source Type: research

Challenges and support for quality of life of youths living with HIV/AIDS in schools and larger community in East Africa: a systematic review
ConclusionYLWHA experience numerous challenges and support needs, some of which occur in schools and affect their QoL. The effects of these challenges are poor health and educational outcomes as well as school dropout. The schools in which youths spend most of their formative years have not provided adequate support for YLWHA. This review identified that although most of the challenges that studies identified arose from within schools and that a few supportive approaches were available, none of the studies explored how these supportive approaches would work in schools. It was additionally identified that stigma complicates...
Source: Systematic Reviews - February 26, 2019 Category: International Medicine & Public Health Source Type: research

Interventions on children ’s and adolescents’ physical activity and sedentary behaviour: protocol for a systematic review from a sex/gender perspective
DiscussionTo our knowledge, our systematic review will be the first to analyse how sex/gender is considered in interventions promoting PA and/or reducing SB in children and adolescents in detail. The review will provide information on how sex/gender aspects have been considered in recent research and the extent to which sex/gender might impact study outcomes. Our findings will be of interest to stakeholders, health promoters, researchers and policy makers who wish to support more equal outcomes from interventions promoting PA and/or reducing SB.Trial registrationPROSPEROCRD42018109528. (Source: Systematic Reviews)
Source: Systematic Reviews - February 26, 2019 Category: International Medicine & Public Health Source Type: research

Evaluation of the effect of insulin sensitivity-enhancing lifestyle- and dietary-related adjuncts on antidepressant treatment response: protocol for a systematic review and meta-analysis
DiscussionThe findings of this review will contribute to the evidence base regarding the utility of non-pharmacological insulin-sensitising treatments in enhancing conventional antidepressant treatment response. (Source: Systematic Reviews)
Source: Systematic Reviews - February 25, 2019 Category: International Medicine & Public Health Source Type: research

Screening for periodontal diseases by non-dental health professionals: a protocol for a systematic review and overview of reviews
The objective of this systematic review is to assess the benefits and risks of screening for periodontal diseases in adults during the periodic health examinations.MethodsWe will use two methodological approaches: (1) a systematic review to assess the effectiveness and risk of harms of screening for periodontal diseases during periodic health examinations and (2) an overview of systematic reviews to determine the effectiveness of treatment approaches for early periodontal disease. We will search electronic databases (Ovid MEDLINE,Embase.com, the Cochrane Library, Epistemonikos, Centre for Reviews and Dissemination database...
Source: Systematic Reviews - February 25, 2019 Category: International Medicine & Public Health Source Type: research

WOMEN's Knowledge of Obstetric Danger signs in Ethiopia (WOMEN's KODE):a systematic review and meta-analysis
ConclusionsWomen ’s knowledge about obstetric danger signs in Ethiopia was very poor, which could hamper access to obstetric care when women encounter obstetric complications. Counselling services during antenatal care and community-based health information dissemination about obstetric danger signs should be stre ngthened.Systematic review registrationPROSPEROCRD42017077000 (Source: Systematic Reviews)
Source: Systematic Reviews - February 25, 2019 Category: International Medicine & Public Health Source Type: research

Gender-based violence among female youths in educational institutions of Sub-Saharan Africa: a systematic review and meta-analysis
AbstractBackgroundGender-based violence is a public health issue. The prevalence of gender-based violence is high in Sub-Saharan Africa. Therefore, this study aims to produce an overall summary estimate on the prevalence of gender-based violence according to different types and its risk factors among female youths in educational institutions of Sub-Saharan Africa.MethodsStudies published in English between 2000 and 2017 were identified by searching electronic databases such as MEDLINE, CINAHL, EMBASE, PsychINFO, and other relevant data bases. Three reviewers independently extracted the data and assessed the quality of stud...
Source: Systematic Reviews - February 25, 2019 Category: International Medicine & Public Health Source Type: research

Prevalence of type 2 diabetes mellitus among hepatitis C virus-infected patients: a protocol for systematic review and meta-analysis
AbstractIntroductionThe ever-increasing global hepatitis C infection is fueling the burden of diabetes mellitus, which exaggerates various complications and may be a cause of death for millions. Several studies have reported that hepatitis C virus infection is an important risk factor for the development of diabetes mellitus. However, the results of fragmented studies reported variable and inconsistent findings on the prevalence of type 2 diabetes mellitus among hepatitis C virus-infected patients. Therefore, this protocol for meta-analysis will determine the overall pooled prevalence of type 2 diabetes mellitus in patient...
Source: Systematic Reviews - February 25, 2019 Category: International Medicine & Public Health Source Type: research

The effect of post mastectomy radiation therapy on breast reconstruction with and without acellular dermal matrix: a systematic review and meta-analysis protocol
ConclusionsTo date, the short- and long-term performance of ADM in the context of postoperative radiation remains unclear. The objective of the present review will be to critically evaluate the literature with the intention of improving postoperative outcomes in the context of mastectomy and radiation. (Source: Systematic Reviews)
Source: Systematic Reviews - February 21, 2019 Category: International Medicine & Public Health Source Type: research