Antiviral treatment for treatment-na ïve chronic hepatitis B: systematic review and network meta-analysis of randomized controlled trials
ConclusionsOur results are consonant with current clinical guidelines and other evidence reviews. For both HBeAg-positive and HBeAg-negative populations, TDF and TAF are the most effective agents for virologic suppression, and TAF is effective across all outcomes. (Source: Systematic Reviews)
Source: Systematic Reviews - August 19, 2019 Category: International Medicine & Public Health Source Type: research

A systematic review of experimental methods to manipulate secondary hyperalgesia in humans: protocol
DiscussionThe results of this review will provide a useful reference for researchers interested in using experimental methods to manipulate secondary hyperalgesia in humans and will help to clarify the relative contributions of different mechanisms to secondary hyperalgesia.Systematic review registrationThis protocol will be registered on PROSPERO before the review begins. Review records will be updated on PROSPERO once the review is complete. This review is intended for publication in a peer-reviewed journal. Analyses and scripts will be made publicly available. (Source: Systematic Reviews)
Source: Systematic Reviews - August 19, 2019 Category: International Medicine & Public Health Source Type: research

Study protocol: Impact of quality improvement interventions on perinatal outcomes in health facilities —a systematic review
DiscussionThis review will inform the global agenda for evidence-based health care by (1) providing a basis for operational guidelines for implementing clinical standards of perinatal care, (2) identify research priorities for generating evidence for QI interventions and (3) QI intervention options with lessons learnt for implementation based on the level of needed resources.Systematic review registrationPROSPERO registration number CRD42018106075 (Source: Systematic Reviews)
Source: Systematic Reviews - August 15, 2019 Category: International Medicine & Public Health Source Type: research

Auriculotherapy to control chemotherapy-induced nausea and vomiting in patients with cancer: protocol of a systematic review
DiscussionThe results of this systematic review will summarize the strength of evidence for the use of auriculotherapy in the control of CINV of patients with cancer and will be used to identify evidence gaps.Systematic review registrationPROSPERO CRD42018117513 (Source: Systematic Reviews)
Source: Systematic Reviews - August 15, 2019 Category: International Medicine & Public Health Source Type: research

Effects of cataract surgery and intra-ocular lens implantation on visual function and quality of life in age-related cataract patients: a systematic review protocol
DiscussionThis systematic review will help in understanding how different types of cataract surgeries and intraocular lenses make a difference on quality of life of age-related cataract patients in terms of visual function and health-related quality of life. As the review attempts to bring together all the cataract-related HRQoL evidences pertaining to different cataract surgical techniques, different intraocular lenses and cataract-related complications, it will also identify gaps in evidence.Systematic review registrationPROSPEROCRD42018092377 (Source: Systematic Reviews)
Source: Systematic Reviews - August 13, 2019 Category: International Medicine & Public Health Source Type: research

Population segmentation based on healthcare needs: a systematic review
Discussion and conclusionsThe underlying segmentation basis of most identified tools was found to be conceptually comparable to each other which suggests a broad recognition of archetypical patient overall healthcare need profiles. While many tools operate based on administrative record data, it is noted that healthcare systems without comprehensive electronic medical records would benefit from tools which segment populations through primary data collection. Future work could therefore include development and validation of such primary data collection-based tools. While this study is limited by exclusion of non-English lit...
Source: Systematic Reviews - August 13, 2019 Category: International Medicine & Public Health Source Type: research

Gender differences in the provision of key post-arrest interventions for out-of-hospital cardiac arrest (OHCA) patients —protocol for a systematic review
DiscussionTo our knowledge, this systematic review will be the first to address the association between patient gender and the provision of post-arrest care. The findings from this systematic review will provide valuable insight to gender disparities in the provision of post-arrest care. This systematic review was designed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. This protocol observes the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) statement.Systematic review registrationPROSPERO CRD42012003096 (Source: Systematic Reviews)
Source: Systematic Reviews - August 13, 2019 Category: International Medicine & Public Health Source Type: research

Memory of pain in adults: a protocol for systematic review and meta-analysis
DiscussionThe question of whether pain is remembered accurately is crucial for valid pain diagnosis, effective treatment and prognosis. So far, a number of studies on memory of pain have been conducted; however, a definitive conclusion on whether memory of pain is accurate is still lacking. In this systematic review and meta-analysis, available data will be pooled together to further inform research and clinical practice.Systematic review registrationPROSPEROCRD42018093523 (Source: Systematic Reviews)
Source: Systematic Reviews - August 13, 2019 Category: International Medicine & Public Health Source Type: research

Health, not weight loss, focused programmes versus conventional weight loss programmes for cardiovascular risk factors: a systematic review and meta-analysis
ConclusionsWe found no long-term significant differences in improved CVD risk factors; however, body satisfaction and restrained eating behaviour improved more with HNWL compared to CWL programmes. Yet firm conclusions cannot be drawn from small studies with high losses to follow-up and data sometimes arising from a single small study.Systematic review registrationPROSPEROCRD42015019505 (Source: Systematic Reviews)
Source: Systematic Reviews - August 10, 2019 Category: International Medicine & Public Health Source Type: research

Performance properties of health-related measurement instruments in whiplash: systematic review protocol
DiscussionThis systematic review will summarize the body of literature on health-related measurement instruments in whiplash, aiming to facilitate the selection of high-quality measurement instrument for researchers and physicians. Findings of this study will guide the ongoing efforts for development of a core outcome set.Systematic review registrationPROSPERO reference numberCRD42018070901 (Source: Systematic Reviews)
Source: Systematic Reviews - August 9, 2019 Category: International Medicine & Public Health Source Type: research

The psychological subtype of intimate partner violence and its effect on mental health: protocol for a systematic review and meta-analysis
AbstractBackground/aimPsychological violence is estimated to be the most common form of intimate partner violence (IPV). Despite this, research on the independent effect of psychological violence on mental health is scarce. Moreover, the lack of a clear and consistent definition of psychological violence has made results difficult to compare. The present study therefore aims to consolidate knowledge on psychological violence by conducting a systematic review and random-effects meta-analysis on the association between psychological violence and mental health problems, when controlling for other types of violence (e.g. physi...
Source: Systematic Reviews - August 9, 2019 Category: International Medicine & Public Health Source Type: research

Effectiveness of treatments for acute and sub-acute mechanical non-specific low back pain: protocol for a systematic review and network meta-analysis
The objective of this study will be to identify the most effective interventions to relieve pain and reduce disability in acute and sub-acute non-specific LBP.Methods/designWe will search electronic databases (MEDLINE, Embase, CENTRAL) from inception onwards. The eligible population will be individuals with non-specific LBP older than 18  years, both males and females, who experience pain less than 6 weeks (acute) or between 6 and 12 weeks (subacute). Eligible interventions and comparators will include all conservative rehabilitation or pharmacological treatments provided by any health professional; th...
Source: Systematic Reviews - August 8, 2019 Category: International Medicine & Public Health Source Type: research

Mapping the evidence of hepatoprotective properties of Moringa oleifera from sub-Saharan African countries: a systematic review protocol
This study aims to establish evidence of the use ofMoringa oleifera in sub-Saharan African countries to manage liver damage conditions in animals.MethodsIn vivo studies will include those in which the activity of the serum levels of hepatic enzymes alanine transaminase (ALT) or serum glutamate-pyruvate transaminase (SGPT), aspartate transaminase (AST) or serum glutamic oxaloacetic transaminase (SGOT), gamma-glutamyltransferase (GGT), alkaline phosphatase (ALP), superoxide dismutase (SOD), catalase (CAT), glutathione reductase (GR), and malondialdehyde (MDA) were measured after administering substances that induced liver in...
Source: Systematic Reviews - August 8, 2019 Category: International Medicine & Public Health Source Type: research

The roles, responsibilities and perceptions of community health workers and ward-based primary health care outreach teams (WBPHCOTs) in South Africa: a scoping review protocol
This study aims to elicit factors enabling or undermining the effectiveness of ward-based primary health care outreach teams in KwaZulu-Natal.MethodsThe search strategy of this scoping review will be guided by Arksey and O ’Malley’s scoping review methodology framework. The following electronic databases will be searched: PubMed, Google Scholar, Science Direct, Clinical key and from EBSCOhost platform and Dissertation via World Cat. The selection of study will involve three stages of screening. The principal autho r will conduct the title screen of articles from the databases and remove the duplicates. Two auth...
Source: Systematic Reviews - August 5, 2019 Category: International Medicine & Public Health Source Type: research

Understanding how and why de-implementation works in health and care: research protocol for a realist synthesis of evidence
DiscussionThis evidence synthesis will address gaps in knowledge about de-implementation across health and care services and ensure that guidance about strategies and approaches accounts for contextual factors, which may be operating at different organisational and decision-making levels. Through the development of the programme theory, which explains what works, how and under which circumstances, findings from the evidence synthesis will support managers and service leaders to make measured decisions about de-implementation.Systematic review registrationPROSPEROCRD42017081030 (Source: Systematic Reviews)
Source: Systematic Reviews - August 5, 2019 Category: International Medicine & Public Health Source Type: research

Impact of balanced versus unbalanced fluid resuscitation on clinical outcomes in critically ill children: protocol for a systematic review and meta-analysis
The objective of the presen t systematic review is to review existing literature to determine the effect of balanced versus unbalanced fluid bolus therapy on metabolic acidosis in critically ill children.MethodsUsing the Preferred Reporting Items for Systematic Review and Meta-analysis Protocols (PRISMA-P) guidelines, we will conduct a systematic review to retrieve all controlled trials and observational studies comparing balanced and unbalanced resuscitative fluids in critically ill children from age 28  days to 18 years old in any resuscitation settings. Search strategy was developed in collaboration with a...
Source: Systematic Reviews - August 5, 2019 Category: International Medicine & Public Health Source Type: research

Measurement properties of self-report pedestrians ’ road crossing behavior questionnaires constructed based on the theory of planned behavior: protocol for a systematic review
DiscussionThe proposed systematic review will evaluate the measurement properties of self-report pedestrians’ road crossing behavior questionnaires constructed based on the TPB. The findings will help researchers in selecting the appropriate TPB-based instrument for pedestrians ’ road crossing behavior.Systematic review registrationPROSPEROCRD42017047793 (Source: Systematic Reviews)
Source: Systematic Reviews - August 3, 2019 Category: International Medicine & Public Health Source Type: research

Time-related changes in quality of life in persons with lower limb amputation or spinal cord injury: protocol for a systematic review
DiscussionThe results of this systematic review will summarise evidence of how QoL changes across the life course, relative to both patient age and time since injury, for both LLA and SCI populations. By enabling a direct comparison of different chronic conditions, disability-specific differences in QoL changes over the life course can be identified.Systematic review registrationPROSPEROCRD42018096633. (Source: Systematic Reviews)
Source: Systematic Reviews - August 2, 2019 Category: International Medicine & Public Health Source Type: research

Communication around HPV vaccination for adolescents in low- and middle-income countries: a systematic scoping overview of systematic reviews
ConclusionsThe small number of studies identified from LMICs is of concern as these countries face the largest burden of disease related to HPV. This scoping overview also found and excluded a number of reviews because of important methodological limitations, highlighting the need for future reviews to use appropriate methods. The overview indicates areas in which further primary studies are needed on HPV vaccination communication in LMICs.Systematic review registrationOpen Science Frameworkhttps://osf.io/agzb4/ (Source: Systematic Reviews)
Source: Systematic Reviews - August 1, 2019 Category: International Medicine & Public Health Source Type: research

Past drivers of and priorities for child undernutrition in South Asia: a mixed methods systematic review protocol
DiscussionThis protocol is guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocols (PRISMA-P) guidelines. The protocol gives an insight into the scope and parameters for the systematic review to be carried out.Systematic review registrationThe protocol was registered by the PROSPERO international prospective register of systematic reviews, referenceCRD42018112696. (Source: Systematic Reviews)
Source: Systematic Reviews - July 31, 2019 Category: International Medicine & Public Health Source Type: research

The evaluation of dual-task conditions on static postural control in the older adults: a systematic review and meta-analysis protocol
DiscussionThe present manuscript wants to provide the protocol that will be used in the systematic review and meta-analysis with the intent to inform the researchers and professionals about the dual-task condition effects. Such will lead future investigations in using the most appropriate dual-task condition.Systematic review registrationPROSPEROCRD42018116597. (Source: Systematic Reviews)
Source: Systematic Reviews - July 27, 2019 Category: International Medicine & Public Health Source Type: research

A systematic review protocol of timing, efficacy and cost effectiveness of upper limb therapy for motor recovery post-stroke
AbstractBackgroundImproving upper limb (UL) motor recovery after stroke represents a major clinical and scientific goal. We aim to complete three systematic reviews to estimate the (1) association between time to start of UL therapy and motor recovery, (2) relative efficacy of different UL therapy approaches post-stroke and (3) cost-effectiveness of UL therapy interventions.MethodsWe have designed a systematic review protocol to address three systematic review questions that were each registered with PROSPERO. The search will be conducted in MEDLINE, EMBASE, and Cochrane Controlled Register of Trials. We will include rando...
Source: Systematic Reviews - July 25, 2019 Category: International Medicine & Public Health Source Type: research

Barriers and facilitators to office-based opioid agonist therapy prescribing and effective interventions to increase provider prescribing: protocol for a systematic review
DiscussionTo date, no synthesis has been undertaken of the barriers and facilitators or effective interventions promoting OAT prescribing by primary care clinicians in community-based comprehensive care settings. Enacting change in physician behaviors, community-based programming, and health services is complex and best informed by using theoretical frameworks that allow the analysis of the available data to assist in designing and implementing interventions. In light of the current opioid crisis, increasing the capacity of primary care clinicians to provide OAT is an important strategy to curb morbidity and mortality from...
Source: Systematic Reviews - July 25, 2019 Category: International Medicine & Public Health Source Type: research

Acculturation and mental health among adult forced migrants: a meta-narrative systematic review protocol
DiscussionA meta-narrative systematic review provides a flexible and systematic approach to synthesising the heterogeneous literature on acculturation and mental health. This review will guide the development of a conceptual framework to aid future research on acculturation among adult forced migrants. As high-income countries seek to integrate forced migrants into society and improve their access to vital resources, this review has the potential to transform policies and practices that influence migrant mental health.Systematic review registrationPROSPEROCRD42018089148 (Source: Systematic Reviews)
Source: Systematic Reviews - July 25, 2019 Category: International Medicine & Public Health Source Type: research

Interventions to promote patients and families ’ involvement in adult intensive care settings: a protocol for a mixed-method systematic review
DiscussionThe review will provide valuable and rigorous insight into the range and quality of interventions available to promote patient and family member involvement in ICU. This is the first step towards addressing the absence of a synthesis of research for this context, and will, in addition, develop a typology of available interventions that will help service users and clinicians make informed decisions about the approaches to patient and family member involvement which they might want to adopt.Systematic review registrationPROSPERO (CRD42018086325). (Source: Systematic Reviews)
Source: Systematic Reviews - July 25, 2019 Category: International Medicine & Public Health Source Type: research

A scoping review of mental health prevention and intervention initiatives for infants and preschoolers at risk for socio-emotional difficulties
ConclusionsKey intervention mechanisms spanned a range of approaches including parenting groups, dyadic, in-home, cognitive-behavioral therapy, and day care-based interventions. The findings are discussed in terms of implications for broad trends and gaps in research and policy for this population. (Source: Systematic Reviews)
Source: Systematic Reviews - July 23, 2019 Category: International Medicine & Public Health Source Type: research

How does feedback shared with interprofessional health care teams shape nursing performance improvement systems? A rapid realist review protocol
This study follows standard guidelines established for realist reviews. Mechanisms at work will be analysed using Actor-Network Theory. All scientific documents are selected from five databases, are published in both English and French between 2010 and 2018, and include empirical research, reviews and grey literature. First, selection of documents will proceed on the basis of titles and abstracts; followed by a second selection by reading the remaining full texts. Inclusion criteria and a data extraction form will be pilot tested with 40 articles prior to completion by two reviewers. Data will be summarised in the form of ...
Source: Systematic Reviews - July 22, 2019 Category: International Medicine & Public Health Source Type: research

Occipital nerve stimulation for non-migrainous chronic headaches: a systematic review protocol
DiscussionThis systematic review will allow us to better evaluate the potential role of ONS for the treatment of patients with chronic headache that are refractory to less invasive therapies. It will help to determine the degree of safety of ONS. Moreover, it will help to design and conduct future randomized controlled trials focused on patients who may better respond to such treatment.Systematic review registrationPROSPEROCRD42019121623 (Source: Systematic Reviews)
Source: Systematic Reviews - July 22, 2019 Category: International Medicine & Public Health Source Type: research

Protocol for a systematic review of the development of depression among adolescents and young adults: psychological, biological, and contextual perspectives around the world
DiscussionThis systematic review will summarize evidence-based research that examines the psychological, biological, and contextual factors contributing to the onset of depression in adolescents across the globe. Results will support the development of a model that can be evaluated in existing cohorts around the world.Systematic review registrationPROSPERO registrationCRD42018103973. (Source: Systematic Reviews)
Source: Systematic Reviews - July 20, 2019 Category: International Medicine & Public Health Source Type: research

Clinical epidemiology and outcomes of ventilator-associated pneumonia in critically ill adult patients: protocol for a large-scale systematic review and planned meta-analysis
DiscussionThe investigation of the epidemiological profiles, prognostic factors, and outcomes associated with VAP is critical for the identification of high-risk groups of mechanically ventilated patients and evaluation of possible clinical endpoints. This may provide substantial links for improved VAP prevention practices targeting modifiable risk factors. Implications for future research directions are discussed.Systematic review registrationPROSPERO CRD42017048158 (Source: Systematic Reviews)
Source: Systematic Reviews - July 20, 2019 Category: International Medicine & Public Health Source Type: research

Understanding school staff members ’ enforcement of school tobacco policies to achieve tobacco-free school: a realist review
ConclusionsBy applying a realist approach, we have been able to detect three CMOs explaining staff members ’ STP enforcement. The findings provide useful insights explaining how stakeholders can support staff members’ STP enforcement and consequently improve the impact of STPs on adolescent smoking. (Source: Systematic Reviews)
Source: Systematic Reviews - July 19, 2019 Category: International Medicine & Public Health Source Type: research

Clowning in children undergoing potentially anxiety-provoking procedures: a systematic review and meta-analysis
ConclusionsClowning seems to lower children ’s anxiety, but because of the increased risk of bias of included studies and the very low quality of evidence, these results should be considered with caution.Systematic review registrationPROSPERO CRD42016039045 (Source: Systematic Reviews)
Source: Systematic Reviews - July 19, 2019 Category: International Medicine & Public Health Source Type: research

The impact of social norms interventions on clinical behaviour change among health workers: protocol for a systematic review and meta-analysis
This study aims to find out whether or not social norms interventions are effective ways of encouraging health workers to carry out desired behaviours and to identify which types of social norms intervention, if any, are most effective.MethodsA systematic review will be conducted. The inclusion criteria are a population of health professionals, a social norms intervention that seeks to change a clinical behaviour, and randomised controlled trials. Searches will be undertaken in MEDLINE, EMBASE, CINAHL, British Nursing Index, ISI Web of Science, PsycINFO and Cochrane trials. Titles and abstracts will be reviewed against the...
Source: Systematic Reviews - July 18, 2019 Category: International Medicine & Public Health Source Type: research

Mapping evidence of the concomitant management of schistosomiasis by traditional health practitioners and health care professionals in communities with high prevalent infections: a systematic scoping review protocol
DiscussionThis review will map the evidence in the literature of the concomitant management of schistosomiasis by THPs and HCPs in communities with a high prevalent infection in LMICs. The review findings will be important for policy makers across the healthcare continuum and be used to inform stakeholders ’ consensus process to explore the development of a generic set of patient-centered quality indicators that are applicable to multiple care settings. It will also identify research gaps in schistosomiasis management in LMICs and provide direction for future research. The results will be disseminat ed through a peer...
Source: Systematic Reviews - July 18, 2019 Category: International Medicine & Public Health Source Type: research

The strong focus on positive results in abstracts may cause bias in systematic reviews: a case study on abstract reporting bias
ConclusionsThis case study on abstract reporting bias shows that (a) more than half of all relevant articles were missed by a conventional search query and (b) this led to an overestimation of the pooled effect. Detection of articles will be improved if all studied exposure and outcome variables are reported in the keywords. The restriction on the maximum number of keywords should be lifted. (Source: Systematic Reviews)
Source: Systematic Reviews - July 17, 2019 Category: International Medicine & Public Health Source Type: research

Risk factors for hearing loss in children: a systematic literature review and meta-analysis protocol
This article presents the protocol for a systematic review that aims to review the risk factors associated with permanent hearing loss in children, including congenital, early, or late onset. Risk factors associated with progressive hearing loss will be investigated as a secondary aim.MethodsScientific literature from the following databases will be investigated: MEDLINE, Ovid MEDLINE(R) Daily and Ovid MEDLINE(R), Embase, and CINAHL. The primary outcome is a permanent bilateral or unilateral hearing loss with congenital onset or onset during childhood (birth to 18  years). The secondary outcome is progressive hearin...
Source: Systematic Reviews - July 17, 2019 Category: International Medicine & Public Health Source Type: research

Women ’s experiences of severe postnatal psychiatric illness: a systematic review protocol
DiscussionTo date, no systematic review following a meta-ethnographic approach on qualitative explorations of mothers worldwide diagnosed with severe postnatal psychiatric illnesses has been conducted. An amalgamation of this information enables a deeper understanding of how severe postnatal psychiatric illnesses manifests across cultures. This information is useful when devising culturally competent care.Systematic review registrationCRD42018093674 (Source: Systematic Reviews)
Source: Systematic Reviews - July 17, 2019 Category: International Medicine & Public Health Source Type: research

Pragmatic methods for reviewing exceptionally large bodies of evidence: systematic mapping review and overview of systematic reviews using lung cancer survival as an exemplar
ConclusionsThe study utilised a novel approach for reviewing an extensive and complicated body of research evidence. It enabled us to address a broad research question and focus on a specific area of priority. The staged approach ensured the review remained relevant to the stakeholders throughout, whilst maintaining the use of objective and transparent methods. It also provided important information on the needs of future research. However, it required extensive planning, management, and ongoing reviewer training. (Source: Systematic Reviews)
Source: Systematic Reviews - July 16, 2019 Category: International Medicine & Public Health Source Type: research

Clarifying differences between reviews within evidence ecosystems
AbstractThis paper builds on a 2012 paper by the same authors which argued that the types and brands of systematic review do not sufficiently differentiate between the many dimensions of different review questions and review methods (Gough et al., Syst Rev 1:28, 2012). The current paper extends this argument by considering the dynamic contexts, or ‘evidence ecosystems’, within which reviews are undertaken; the fact that these ecosystems are constantly changing; and the relevance of this broader context for understanding ‘dimensions of difference’ in the unfolding development and refinement of review...
Source: Systematic Reviews - July 15, 2019 Category: International Medicine & Public Health Source Type: research

Short-term versus long-term psychotherapy for adult psychiatric disorders: a protocol for a systematic review with meta-analysis and trial sequential analysis
DiscussionAs psychotherapy is among the treatments of choice for most adult psychiatric disorders, a systematic review evaluating the benefits and harms of short-term compared with long-term psychotherapy is urgently needed. It is the hope that this review will be able to inform best practice in treatment and clinical research of these highly prevalent and burdensome disorders.Systematic review registrationPROSPEROCRD42019128535 (Source: Systematic Reviews)
Source: Systematic Reviews - July 13, 2019 Category: International Medicine & Public Health Source Type: research

Does routine surveillance imaging after completing treatment for childhood solid tumours cause more harm than good? A systematic review and meta-analysis protocol
DiscussionThe aim of routine surveillance imaging is to detect recurrence of disease before clinical symptoms and signs develop. Some studies have suggested that most relapses of childhood cancer are detected due to clinical symptoms or signs, particularly in those with extra-cranial solid tumours, and when these relapses are detected by imaging, there is no increase in survival. This review aims to establish whether routine surveillance imaging is beneficial, as well as evaluating the potential negative impacts of surveillance programmes.Systematic review registrationPROSPEROCRD42018103764 (Source: Systematic Reviews)
Source: Systematic Reviews - July 12, 2019 Category: International Medicine & Public Health Source Type: research

Association between subthreshold depression and self-care behaviour in people with type 2 diabetes: a protocol for systematic review of observational studies
The objective of this systematic review is to determine the association between subthreshold depression and self-care behaviour in adults with type 2 diabetes.MethodsThis protocol will follow the guideline of the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols 2015 (PRISMA-P-2015). A systematic search of literature will be conducted for observational studies reporting the association between subthreshold depression and self-care behaviour in adults aged 18 years or over and diagnosed with type 2 diabetes. Electronic databases including MEDLINE, EMBASE, PsycINFO, Emcare and CINAHL will be searche...
Source: Systematic Reviews - July 12, 2019 Category: International Medicine & Public Health Source Type: research

Toward systematic review automation: a practical guide to using machine learning tools in research synthesis
AbstractTechnologies and methods to speed up the production of systematic reviews by reducing the manual labour involved have recently emerged. Automation has been proposed or used to expedite most steps of the systematic review process, including search, screening, and data extraction. However, how these technologies work in practice and when (and when not) to use them is often not clear to practitioners. In this practical guide, we provide an overview of current machine learning methods that have been proposed to expedite evidence synthesis. We also offer guidance on which of these are ready for use, their strengths and ...
Source: Systematic Reviews - July 11, 2019 Category: International Medicine & Public Health Source Type: research

Influence of health interventions on quality of life in seriously ill children at the end of life: a systematic review protocol
DiscussionAs part of a larger project, we will use the results of this review to identify a first set of quality indicators for the care for children at the end of life. Reviewing the current span of evidence and identifying research gaps will uncover future research priorities into the care for children at the end of life.Systematic review registrationPROSPERO CRD42018105109 (Source: Systematic Reviews)
Source: Systematic Reviews - July 11, 2019 Category: International Medicine & Public Health Source Type: research

Physically aggressive behaviors in older people living with cognitive disorders: a systematic scoping review protocol
DiscussionNo scoping review has been found on the physically aggressive behaviors of older people living with cognitive impairment in various settings. The results of this review will identify needs for further research and for clinical and training development on this problem from a humanist standpoint.Systematic review registrationCurrently, it is not possible to register a systematic scoping review protocol (e.g., PROSPERO). (Source: Systematic Reviews)
Source: Systematic Reviews - July 11, 2019 Category: International Medicine & Public Health Source Type: research

Steps toward more complete reporting of systematic reviews of diagnostic test accuracy: Preferred Reporting Items for Systematic Reviews and Meta-Analyses of Diagnostic Test Accuracy (PRISMA-DTA)
AbstractReporting standards in biomedical research have been shown to be suboptimal. The publication of the PRISMA statement has improved the completeness of reporting of systematic reviews, but several issues specific to diagnostic test accuracy are not included in the PRISMA statement. Therefore, a diagnostic test accuracy extension of the PRISMA statement, PRISMA-DTA, was created. This commentary addresses completeness of reporting in systematic reviews, the PRISMA-DTA statement, and strategies for optimal uptake of reporting guidelines. (Source: Systematic Reviews)
Source: Systematic Reviews - July 11, 2019 Category: International Medicine & Public Health Source Type: research

Mapping evidence on tuberculosis active case finding policies, strategies, and interventions for tuberculosis key populations: a systematic scoping review protocol
This study will be guided by the scoping review framework, proposed by Arksey and O ’Malley. A comprehensive literature search will be performed in the following electronic databases: PubMed, SCOPUS, Web of Science, Science Direct, and EBSCOhost (Academic search complete, PsycINFO, Health Sources, CINAHL, and MEDLINE with full text). Primary studies both published in peer-reviewe d journals and grey literature such as unpublished studies, thesis, and studies in press addressing our research question will be included. To reduce selection bias, two independent reviewers will perform title, abstract, and full article sc...
Source: Systematic Reviews - July 10, 2019 Category: International Medicine & Public Health Source Type: research

Sexual dysfunction and related factors in pregnancy and postpartum: a systematic review and meta-analysis protocol
DiscussionThis systematic review addresses the factors associated with sexual dysfunction during pregnancy and postpartum. Considering the high prevalence of sexual dysfunction among women, the treatment of this problem has been highly sought after by the World Health Organization in recent years. The results of this study can help discover new strategies by introducing factors affecting women ’s sexual dysfunction, thereby eliminating or diminishing these factors, and play an important role in improving the quality of life of women during pregnancy and postpartum periods.Systematic review registrationPROSPEROCRD4201...
Source: Systematic Reviews - July 5, 2019 Category: International Medicine & Public Health Source Type: research

Measuring awareness in people with dementia: protocol for a scoping review
DiscussionThis scoping review will provide an overview of the methods used to measure awareness in people with dementia, allowing comparison of the methods along with identification of validated measures. The methods or components will be appraised for potential clinical use, and gaps in research will be highlighted. (Source: Systematic Reviews)
Source: Systematic Reviews - July 4, 2019 Category: International Medicine & Public Health Source Type: research

Evidence of perpetration of intimate partner violence among HIV-positive couples: a systematic scoping review protocol
ConclusionThe authors hope to find studies on intimate partner violence among HIV-positive couples to establish gaps where primary research will be necessary.Systematic review registrationPROSPERO CRD42017062190 (Source: Systematic Reviews)
Source: Systematic Reviews - July 3, 2019 Category: International Medicine & Public Health Source Type: research