Exploring prevention and mitigation strategies to reduce the health impacts of occupational exposure to wildfires for wildland firefighters and related personnel: protocol of a scoping study
DiscussionThis two-phase approach will provide an in-depth review of the literature of the health impacts of occupational exposure to wildfires and identify mitigation strategies or policies implemented to protect workers and reduce negative health impacts. It is anticipated that these findings may provide recommendations for “quick wins” or initial action that can be implemented within the BC context to reduce negative health outcomes, and inform gaps in context-specific research that needs to be addressed through a strategic, collaborative research program over the next 5 years.Systematic review regist...
Source: Systematic Reviews - May 29, 2020 Category: International Medicine & Public Health Source Type: research

How effective are digital interventions in increasing flu vaccination amongst pregnant women? A systematic review protocol
DiscussionThis is the first known systematic review to examine the effectiveness of digital interventions in increasing the rate of flu vaccination amongst pregnant women. This review has the potential to inform whether digital interventions are an appropriate and successful method of increasing flu vaccination amongst pregnant women, and to determine which mode of digital intervention is most effective.Trial registrationThis systematic review is registered on the international prospective register of systematic reviews (PROSPERO). Registration number pending. (Source: Systematic Reviews)
Source: Systematic Reviews - May 28, 2020 Category: International Medicine & Public Health Source Type: research

Efficacy of tubing technique with biomaterials compared to direct coaptation technique after peripheral neurotmesis in nerve healing and return to functionality in young adult rats: a systematic review protocol
DiscussionThis systematic review of animal studies will identify, evaluate, and synthetize the evidence on the the efficacy of tubing technique with biomaterials compared to direct coaptation technique after peripheral neurotmesis in nerve healing and return to functionality.Systematic review registrationPROSPEROCRD42018106042. (Source: Systematic Reviews)
Source: Systematic Reviews - May 28, 2020 Category: International Medicine & Public Health Source Type: research

Advancing mental health equality: a mapping review of interventions, economic evaluations and barriers and facilitators
ConclusionsThe mapping review was useful in assessing the spread of literature and identifying highly researched areas versus prominent gaps. The findings are useful for clinicians, commissioners and service providers seeking to understand strategies to support the advancement of mental health equality for different populations and could be used to inform further research and support local decision-making.Systematic review registrationNot applicable. (Source: Systematic Reviews)
Source: Systematic Reviews - May 26, 2020 Category: International Medicine & Public Health Source Type: research

Locating unregistered and unreported data for use in a social science systematic review and meta-analysis
AbstractMeta-analysts rely on the availability of data from previously conducted studies. That is, they rely on primary study authors to register their outcome data, either in a study ’s text or on publicly available websites, and report the results of their work, either again in a study’s text or on publicly accessible data repositories. If a primary study author does not register data collection and similarly does not report the data collection results, the meta-analyst is at risk of failing to include the collected data. The purpose of this study is to attempt to locate one type of meta-analytic data: findin...
Source: Systematic Reviews - May 26, 2020 Category: International Medicine & Public Health Source Type: research

Does suboptimal household flooring increase the risk of diarrhoea and intestinal parasite infection in low and middle income endemic settings? A systematic review and meta-analysis protocol
DiscussionThis review will provide a comprehensive examination of a possible association between suboptimal household flooring and increased risk of enteric pathogen infection, highlight gaps for future research in high risk areas, and inform intervention design for future planned studies in Kenya and/or elsewhere in the region.Systematic review registrationPROSPERO registration number: CRD42019156437 (Source: Systematic Reviews)
Source: Systematic Reviews - May 20, 2020 Category: International Medicine & Public Health Source Type: research

Mapping global evidence on strategies and interventions in neurotrauma and road traffic collisions prevention: a scoping review
ConclusionsThere is a large quantity of global evidence on strategies and interventions for neurotrauma and RTCs prevention. However, fewer papers were from LMICs, especially on secondary and tertiary prevention. More primary research needs to be done in these countries to determine what strategies and interventions exist and the applicability of HIC interventions in LMICs. (Source: Systematic Reviews)
Source: Systematic Reviews - May 20, 2020 Category: International Medicine & Public Health Source Type: research

Improving the usefulness of evidence concerning the effectiveness of implementation strategies for knowledge products in primary healthcare: protocol for a series of systematic reviews
DiscussionOur results could inform not only the overviews ’ methodology but also the development of an online platform for the implementation strategies of knowledge products. This platform could be useful for stakeholders in implementation science.Systematic review registrationProtocol registered on Open Science Framework,https://osf.io/eb8w2/. (Source: Systematic Reviews)
Source: Systematic Reviews - May 19, 2020 Category: International Medicine & Public Health Source Type: research

Vitamin B —Can it prevent cognitive decline? A systematic review and meta-analysis
DiscussionWe found no overall evidence that oral vitamin B supplementation prevented cognitive decline. The isolated significant effects that were reported could be attributed to methodological issues. The results of this review do not provide evidence that population groups with certain risk factors would profit more from the intervention than others. Our findings do not apply to forms of administration other than oral supplementation nor do they offer information regarding the treatment of cognitively impaired individuals via the administration of vitamin B.Systematic review registrationPROSPERO CRD42017071692 (Source: Systematic Reviews)
Source: Systematic Reviews - May 15, 2020 Category: International Medicine & Public Health Source Type: research

Physical activity promotion for multimorbid patients in primary care settings: a protocol for a systematic review evaluating health benefits and harms
The objective of this study will be to evaluate the health benefits and harms of PA interventions for sedentary adults with multimorbidity in primary care settings.MethodsThis is the study protocol for a systematic review. We will search PubMed, MEDLINE (Ovid), Web of Science, CINHAL, and the Cochrane Library (from inception onwards). In addition, clinical trial registers and reference lists of included studies will be searched. We will include randomized controlled trials, quasi-experimental, and non-randomized trials examining the health benefits and harms of PA interventions with or without additional lifestyle interven...
Source: Systematic Reviews - May 13, 2020 Category: International Medicine & Public Health Source Type: research

Interventions for treatment of COVID-19: a protocol for a living systematic review with network meta-analysis including individual patient data (The LIVING Project)
DiscussionCOVID-19 has become a pandemic with substantial mortality. A living systematic review evaluating the beneficial and harmful effects of pharmacological and other interventions is urgently needed. This review will continuously inform best practice in treatment and clinical research of this highly prevalent disease.Systematic review registrationPROSPERO CRD42020178787 (Source: Systematic Reviews)
Source: Systematic Reviews - May 9, 2020 Category: International Medicine & Public Health Source Type: research

Association between pesticide exposure and paraoxonase-1 ( PON1 ) polymorphisms, and neurobehavioural outcomes in children: a systematic review
AbstractEnvironmental factors such as pollution, pesticide exposure and socio-demographic location have been implicated as a pressure capable of altering genetic make-up. Altered genetic sequence of genes encoding enzymes may result in single nucleotide polymorphism (SNP). Of peculiar interest is the genetic variance on the paraoxonase-1 gene induced by pre- and postnatal exposure to pesticides. SNP have been reported on the paraoxonase-1 gene and post-xenobiotic exposure and are presumed to alter gene sequence and ultimately enzymatic activity. The altered enzymatic activity may facilitate neurodevelopment disorders. Auti...
Source: Systematic Reviews - May 9, 2020 Category: International Medicine & Public Health Source Type: research

Systematic review of patient-oriented interventions to reduce unnecessary use of antibiotics for upper respiratory tract infections
ConclusionsPatient-oriented interventions (especially delayed prescriptions) may be effective in reducing antibiotic prescription for URTIs. Further research is needed to investigate the costs and feasibility of implementing these interventions as part of routine clinical practice.Systematic review registrationPROSPEROCRD42016048007. (Source: Systematic Reviews)
Source: Systematic Reviews - May 8, 2020 Category: International Medicine & Public Health Source Type: research

Physiologic perfusion monitoring methods during endovascular revascularization for atherosclerotic peripheral arterial disease: protocol for a systematic review
DiscussionThe treatment of peripheral arterial disease is unique in that the tissue of the ischemic leg is easily accessible for direct monitoring during procedures. This is contrasted with cardiac and neurologic monitoring during cardiac and cerebral procedures, where indirect or invasive measures are required to monitor organ perfusion. Currently synthesized evidence describing limb perfusion focuses on static states of ischemia, and does not evaluate the value of change in perfusion measurement as an indicator of endovascular treatment success. These methods could potentially be applied to optimize procedural outcomes b...
Source: Systematic Reviews - May 8, 2020 Category: International Medicine & Public Health Source Type: research

Determining optimal strategies for primary prevention of cardiovascular disease: systematic review, cost-effectiveness review and network meta-analysis protocol
DiscussionThe results will be important for policymakers when making decisions between multiple possible alternative strategies to prevent CVD. Compared to results from existing multiple separate pairwise meta-analyses, this overarching synthesis of all relevant work will enhance decision-making. The findings will be crucial to inform evidence-based priorities and guidelines for policies and planning prevention strategies of CVD.Systematic review registrationPROSPEROCRD42019123940. (Source: Systematic Reviews)
Source: Systematic Reviews - May 7, 2020 Category: International Medicine & Public Health Source Type: research

Increased circulating vascular endothelial growth factor in acute myeloid leukemia patients: a systematic review and meta-analysis
AbstractBackgroundVascular endothelial growth factor (VEGF) is one of the angiogenesis regulators, which plays an important role in tumor angiogenesis and tumor progression. Current studies have found that VEGF plays an important role in hematologic diseases including acute myeloid leukemia (AML). However, the circulating levels of VEGF in AML were still controversial among published studies.MethodsThree databases including PubMed, EMBASE, and Cochrane Library databases were searched up to February 2020. All articles included in the meta-analysis met our inclusion and exclusion criteria. Studies will be screened and data e...
Source: Systematic Reviews - May 6, 2020 Category: International Medicine & Public Health Source Type: research

Novel wearable and contactless monitoring devices to identify deteriorating patients in the clinical setting: a systematic review protocol
DiscussionWhile novel monitoring devices are often proposed as a solution to problems with infection, discomfort, and frequency of monitoring in the clinical setting it has not yet been established which devices have been validated in clinical settings in the pathological ranges of vital signs that reflect patient deterioration. It is equally unclear what additional value these devices might provide. This systematic review will synthesize published data regarding devices that have been tested and validated in patients AND in a clinical setting AND in reference ranges that reflect severe illness.Systematic review registrati...
Source: Systematic Reviews - May 6, 2020 Category: International Medicine & Public Health Source Type: research

A focus on cross-purpose tools, automated recognition of study design in multiple disciplines, and evaluation of automation tools: a summary of significant discussions at the fourth meeting of the International Collaboration for Automation of Systematic Reviews (ICASR)
AbstractThe fourth meeting of the International Collaboration for Automation of Systematic Reviews (ICASR) was held 5 –6 November 2019 in The Hague, the Netherlands. ICASR is an interdisciplinary group whose goal is to maximize the use of technology for conducting rapid, accurate, and efficient systematic reviews of scientific evidence. The group seeks to facilitate the development and acceptance of automated tec hniques for systematic reviews. In 2018, the major themes discussed were the transferability of automation tools (i.e., tools developed for other purposes that might be used by systematic reviewers), the aut...
Source: Systematic Reviews - May 4, 2020 Category: International Medicine & Public Health Source Type: research

The prevalence of type 2 diabetes in people with psychiatric disorders: an umbrella review protocol
DiscussionFor each psychiatric disorder, the data regarding the prevalence of type 2 diabetes will be summarized and discussed. When possible, comparisons with control groups will be reported and discussed. Finally, future implications and recommendations for clinical care will be presented.Systematic review registrationThis protocol was submitted for registration with the International Prospective Register of Systematic Reviews (PROSPERO) on December 9, 2019 (registration number: pending). (Source: Systematic Reviews)
Source: Systematic Reviews - May 4, 2020 Category: International Medicine & Public Health Source Type: research

Associations of loneliness and social isolation with cardiovascular and metabolic health: a systematic review and meta-analysis protocol
DiscussionThis proposed systematic review and meta-analysis will identify and synthesise evidence to determine if there is an association between loneliness, social isolation, and cardiovascular/metabolic risk factors, with a special focus on severe mental illnesses. The results will help determine links and promising avenues of further research.Systematic review registrationPROSPEROCRD42018111911 (Source: Systematic Reviews)
Source: Systematic Reviews - May 4, 2020 Category: International Medicine & Public Health Source Type: research

Prevalence of hypertension and its risk factors among cotton textile workers in low- and middle-income countries: a protocol for a systematic review
The objective of this study will be to evaluate the prevalence of hypertension and its risk factors among adult cotton textile workers in low- and middle-income countries.MethodsWe designed and registered a study protocol for a systematic review of descriptive epidemiology data. We will include observational studies (e.g., cross-sectional, cohort, surveys) on the epidemiology of hypertension among adult cotton textile workers in low- and middle-income countries. The primary outcome will be the prevalence of hypertension. Secondary outcomes will be the prevalence of risk factors of hypertension. Literature searches will be ...
Source: Systematic Reviews - May 2, 2020 Category: International Medicine & Public Health Source Type: research

A scoping review of network meta-analyses assessing the efficacy and safety of complementary and alternative medicine interventions
ConclusionThe use of NMA to assess the effectiveness of CAM interventions is growing rapidly. Efforts to identify priority topics for future CAM-related NMAs and to enhance methods for CAM comparisons with conventional medicine are needed.Systematic review registrationhttps://ruor.uottawa.ca/handle/10393/35658 (Source: Systematic Reviews)
Source: Systematic Reviews - April 30, 2020 Category: International Medicine & Public Health Source Type: research

Safety and efficiency of gasless laparoscopy: a systematic review protocol
This study will be a comprehensive review on all published articles found using this search strategy on the safety and efficiency of the use of gasless laparoscopy. The systematic review outcomes will include safety and efficiency of gasless laparoscopy compared to the use of conventional laparoscopy or laparotomy.Trial registrationThe study has been registered in PROSPERO under registration number:CRD42017078338 (Source: Systematic Reviews)
Source: Systematic Reviews - April 30, 2020 Category: International Medicine & Public Health Source Type: research

The role of exposure in the treatment of anxiety in children and adolescents: protocol of a systematic review and meta-analysis
DiscussionThis systematic review and meta-analysis will examine the role of exposure in reducing symptoms of anxiety among youth. The review will provide information on the working mechanisms underlying the efficacy of CBT. Our findings will be of interest to mental health professionals, researchers, and policy makers who wish to support children and adolescents with anxiety disorders by guiding well-informed treatment decisions.Systematic review registrationPROSPERO (CRD42019128667). (Source: Systematic Reviews)
Source: Systematic Reviews - April 27, 2020 Category: International Medicine & Public Health Source Type: research

Noninvasive oxygenation strategies in adult patients with acute respiratory failure: a protocol for a systematic review and network meta-analysis
This study will help to guide clinical decision-making when caring for adult patients with acute hypoxemic respiratory failure and improve our understanding of the limitations of the available literature assessing noninvasive oxygenation strategies in acute hypoxemic respiratory failure.Systematic review registrationPROSPEROCRD42019121755 (Source: Systematic Reviews)
Source: Systematic Reviews - April 26, 2020 Category: International Medicine & Public Health Source Type: research

The influence of contextual factors on healthcare quality improvement initiatives: a realist review
ConclusionsThis is the first realist review of context in QI and contributes to a deeper understanding of how context influences quality improvement initiatives. The distillation of key contextual factors offers the potential to inform the design and development of context-sensitive interventions to enhance improvement initiatives and address the challenge of spread and sustainability. Future research should explore the application of our conceptual model to enhance improvement-planning processes.Systematic review registrationPROSPERO CRD42017062135 (Source: Systematic Reviews)
Source: Systematic Reviews - April 26, 2020 Category: International Medicine & Public Health Source Type: research

HIV-1 integrase resistance associated mutations and the use of dolutegravir in Sub-Saharan Africa: a systematic review and meta-analysis protocol
DiscussionThis review will help to strengthen evidence on the effectiveness of integrase strand transfer inhibitors by contributing to current knowledge on the use of dolutegravir and/or raltegravir (especially for neonates) in Sub-Saharan Africa. Results will therefore help in setting-up baseline data for an optimal management of people living with HIV as Sub-Saharan African countries are transitioning to dolutegravir-based regimens. Evidence will also support HIV/AIDS programs in identifying gaps and actions to be undertaken for improved long-term care and treatment of people living with HIV in Sub-Saharan Africa.Systema...
Source: Systematic Reviews - April 25, 2020 Category: International Medicine & Public Health Source Type: research

Barriers and facilitators to implementation of epilepsy self-management programs: a systematic review using qualitative evidence synthesis methods
ConclusionIdentification of facilitators and barriers at multiple levels provides insight into disease-specific factors that influence implementation and adoption of self-management programs for individuals with epilepsy. Our findings indicate that involving individuals with epilepsy and their caregivers in intervention development, and then tailoring intervention content during the intervention, can help ensure the content is relevant to intervention participants. Our findings also indicate the role of the clinician (i.e., the individual who provides self-management education) is important to intervention implementation, ...
Source: Systematic Reviews - April 25, 2020 Category: International Medicine & Public Health Source Type: research

A systematic review and taxonomy of tools for evaluating evidence-based medicine teaching in medical education
ConclusionsSix tools of reasonable validity are available for evaluating most steps of EBM and some domains of EBM learning. Further development and validation of tools that evaluate all the steps in EBM and all educational outcome domains are needed.Systematic review registrationPROSPEROCRD42018116203. (Source: Systematic Reviews)
Source: Systematic Reviews - April 24, 2020 Category: International Medicine & Public Health Source Type: research

School-going transgender youths ’ experiences at health care facilities: a systematic scoping review protocol
DiscussionWe anticipate mapping the experiences of school-going transgender youth at health care facilities. Once summarized, the data could be useful to clinical educators, health workers, policy makers, and guide future research to ensure that the human and patients ’ rights of transgender youth, are globally acknowledged, protected, and respected within health care facilities. (Source: Systematic Reviews)
Source: Systematic Reviews - April 24, 2020 Category: International Medicine & Public Health Source Type: research

Antibiotic prophylaxis in transurethral resection of bladder tumours: study protocol for a systematic review and meta-analysis
The objective of this systematic review and meta-analysis is to compare the impact of different antimicrobial prophylaxis schemes versus placebo on the prevention of postoperative UTI and asymptomatic bacteriuria.MethodsWe designed and registered a study protocol for a systematic review and meta-analysis of randomized controlled trials and non-randomized (e.g. cohort, case-control) studies examining any form of antibiotic prophylaxis in patients with transurethral resection of bladder tumours. Literature searches will be conducted in several electronic databases (from inception onwards), including MEDLINE (Ovid), EMBASE (O...
Source: Systematic Reviews - April 23, 2020 Category: International Medicine & Public Health Source Type: research

The interplay of HIV and human papillomavirus-related cancers in sub-Saharan Africa: scoping review
ConclusionHIV positivity is associated with increased prevalence of HPV infection on different anatomic sites, which will result in increased burden of HPV-related cancers among PLHIV. Furthermore, primary studies with robust study designs aimed at investigating the risk developing HPV-related cancers among PLHIV are recommended.Systematic review registration: PROSPERO CRD42017062403 (Source: Systematic Reviews)
Source: Systematic Reviews - April 22, 2020 Category: International Medicine & Public Health Source Type: research

School-based interventions for promoting food and nutrition literacy (FNLIT) in elementary school children: a systematic review protocol
DiscussionThis systematic review will summarize the evidence regarding the components, implementation methods, and effectiveness of the interventions of food and nutrition literacy promotion in elementary school children. The results of this review will provide a useful reference for policymakers and curriculum developers to assess education curricula and develop practical learning and teaching strategies to improve students ’ food and nutrition literacy.Systematic review registrationPROSPERO (CRD42019135118) (Source: Systematic Reviews)
Source: Systematic Reviews - April 22, 2020 Category: International Medicine & Public Health Source Type: research

The scope of tobacco cessation randomized controlled trials in low- to middle-income countries: protocol for a scoping review
DiscussionAs researchers attempt to minimize the harms from tobacco in LMICs, they need to be aware of scientific evidence to develop RCTs to achieve their aim. The review will complement the evidence base on tobacco cessation in LMICs. (Source: Systematic Reviews)
Source: Systematic Reviews - April 21, 2020 Category: International Medicine & Public Health Source Type: research

Surgical treatments for women with stress urinary incontinence: a systematic review of economic evidence
ConclusionsThe review has shown that methods used for the economic evaluation of surgical treatments for SUI vary widely in terms of study design, analysis type, compared alternatives, time horizon, costing methodologies and effect outcomes. Future economic evaluation studies on surgical treatments for SUI may be improved by the application of available guidelines.Systematic review registrationRegistered in PROSPERO in 2016,CRD42016049339 (Source: Systematic Reviews)
Source: Systematic Reviews - April 20, 2020 Category: International Medicine & Public Health Source Type: research

Health and well-being literacy initiatives focusing on immigrant communities: an environmental scan protocol to identify & quot;what works and what does not & quot;
This study will gather information from existing literature and online sources as well as will capture expert and lay perspectives on the factors that can impact the effectiveness and sustainability of CBHWLIs through conducting a comprehensive environmental scan: (i) a systematic scoping review of published literature and grey literature, (ii) a comprehensive Internet search, (iii) key informant interviews, and (iv) community consultation. Specific methodological and analytical frameworks will guide each step.Ethics and disseminationThis study is the first step in establishing a practical base for developing CBHWLI implem...
Source: Systematic Reviews - April 20, 2020 Category: International Medicine & Public Health Source Type: research

Epidemiology of rheumatoid arthritis in sub-Saharan Africa: a systematic review and meta-analysis protocol
DiscussionThis systematic review and meta-analysis shall quantify the magnitude of RA morbidity and mortality in sub-Saharan Africa. Results from this review will be disseminated in peer-reviewed journals, conferences and on social media platforms.Systematic review registrationPROSPEROCRD42020153483 (Source: Systematic Reviews)
Source: Systematic Reviews - April 17, 2020 Category: International Medicine & Public Health Source Type: research

Effectiveness and cost-effectiveness of telehealth in rural and remote emergency departments: a systematic review protocol
DiscussionThis review will identify gaps in the current body of evidence relating to the effectiveness and cost-effectiveness of rural and remote emergency telehealth services. By confining to articles written in the English language, this analysis may be subjected to publication bias and results need to be interpreted accordingly. We believe the results of this review could be valuable for the design of future economic evaluations of emergency telehealth services implemented in the rural and remote context.Systematic review registrationPROSPEROCRD42019145903 (Source: Systematic Reviews)
Source: Systematic Reviews - April 17, 2020 Category: International Medicine & Public Health Source Type: research

Protocol for a systematic review of self-management interventions for older adults living with cancer
This study will inform future intervention development by identifying gaps and strengths in effective self-management interventions targeting the needs of older adults receiving active treatment for cancer.Systematic review registrationPROPERO registry ID#CRD42019134113 (Source: Systematic Reviews)
Source: Systematic Reviews - April 17, 2020 Category: International Medicine & Public Health Source Type: research

Global incidence of incomplete surgical excision in adult patients with non-melanoma skin cancer: study protocol for a systematic review and meta-analysis of observational studies
The objective of this study will be to systematically evaluate observational data that present incidence of incomplete surgical excision amongst adult patients with non-melanoma skin cancer worldwide.MethodsWe designed and registered a study protocol for a systematic review and meta-analysis of descriptive epidemiology data. A comprehensive literature search will be conducted (from January 2000 onwards) in MEDLINE, EMBASE, Scopus, CINAHL, EMCare and Cochrane Library. Grey literature will be identified through searching Open Grey, dissertation databases (e.g. Open Access Theses and Dissertations) and clinical trial register...
Source: Systematic Reviews - April 17, 2020 Category: International Medicine & Public Health Source Type: research

Treatment of pre- and confirmed cervical cancer in HIV-seropositive women from developing countries: a systematic review
ConclusionsTreatment of cervical cancer is based on the stage of cancer, and poor outcomes in most developing countries might be due to a lack of optimal treatment regimen. Those infected with HIV were younger and had advanced cervical cancer as compared to those who were HIV-negative. Facilitation and putting HIV-infected people on life-long ART is of importance and has been found to have a positive impact on cervical cancer treatment response. Research on precancerous lesions and cervical cancer management of HIV-seropositive patients focusing on the quality of life of those treated; the effectiveness of the treatment me...
Source: Systematic Reviews - April 10, 2020 Category: International Medicine & Public Health Source Type: research

Reporting of financial conflicts of interest in meta-analyses of drug trials published in high-impact medical journals: comparison of results from 2017 to 2018 and 2009
ConclusionsReporting of drug trial sponsorship and author FCOIs in meta-analyses published in high-impact journals has increased since 2009 but is still suboptimal. Standards on reporting of trial funding described in the forthcoming revised PRISMA statement should be adapted and enforced by journals to improve reporting. (Source: Systematic Reviews)
Source: Systematic Reviews - April 8, 2020 Category: International Medicine & Public Health Source Type: research

The ability of late pregnancy maternal tests to predict adverse pregnancy outcomes associated with placental dysfunction (specifically fetal growth restriction and pre-eclampsia): a protocol for a systematic review and meta-analysis of prognostic accuracy studies
DiscussionThis review will assess whether current published data reporting either a single or combination of tests in late pregnancy can accurately predict adverse pregnancy outcome(s) associated with placental dysfunction. Accurate prediction could allow targeted management and possible intervention for high-risk pregnancies, ultimately avoiding adverse outcomes associated with placental disease.Systematic review registrationPROSPEROCRD42018107049 (Source: Systematic Reviews)
Source: Systematic Reviews - April 8, 2020 Category: International Medicine & Public Health Source Type: research

Protocol for a scoping review of the current data practices in forensic medicine
DiscussionThe results of this review will identify and describe data capturing, management, and storage practices for use in forensic medicine. It will also review the efficiency of the different data systems and report where possible on the uses of the data system within the forensic medicine and pathology field.Ethics and disseminationAlthough research ethics approval is not required for this scoping review because the study will not include human or animal participants, the study was submitted for approval to the University of Kwazulu Natal Biomedical Research Ethics Committee and obtained provisional approval. Data wil...
Source: Systematic Reviews - April 8, 2020 Category: International Medicine & Public Health Source Type: research

Traditional Chinese herbal medicine for treating novel coronavirus (COVID-19) pneumonia: protocol for a systematic review and meta-analysis
AbstractBackgroundA new type of coronavirus, novel coronavirus (COVID-19), is causing an increasing number of cases of pneumonia and was declared a Public Health Emergency of International Concern by the World Health Organization on 30 January 2020. The virus first appeared in Wuhan, China, in late December 2019, and traditional Chinese herbal medicine is being used for its treatment. This systematic review and meta-analysis will assess studies of the effects of traditional Chinese herbal medicine in COVID-19 pneumonia.MethodsWe will search electronic databases including PubMed, Embase, the Cochrane Central Register of Con...
Source: Systematic Reviews - April 8, 2020 Category: International Medicine & Public Health Source Type: research

Effectiveness of autogenic training on psychological well-being and quality of life in adults living with chronic physical health problems: a protocol for a systematic review of RCT
DiscussionAutogenic training appears to be a promising therapy to improve psychological well-being and quality of life in people living with chronic physical health problems, but no recent reports have synthesized the available evidence in this population. The results of this review will examine and synthesize the evidence on the benefits and harms of autogenic training on psychological well-being and quality of life in people living with chronic physical health problems, thus supporting the development of best practices for complementary approaches.Systematic review registrationPROSPEROCRD42018105347. (Source: Systematic Reviews)
Source: Systematic Reviews - April 7, 2020 Category: International Medicine & Public Health Source Type: research

A protocol for a systematic review and meta-analysis of the diagnostic accuracy of mid-regional pro-adrenomedullin in predicting invasive bacterial infection in children
DiscussionThis review will report the normal ranges for MR-proADM in health and the diagnostic accuracy of MR-proADM at identifying children with IBI. The review will help to define where in the diagnostic pathway MR-proADM could be useful including potential as a point-of-care test for children at first presentation with IBI.Systematic review registrationPROSPEROCRD42018096295 (Source: Systematic Reviews)
Source: Systematic Reviews - April 2, 2020 Category: International Medicine & Public Health Source Type: research

Air ambulance outcome measures using Institutes of Medicine and Donabedian quality frameworks: protocol for a systematic scoping review
The objective of this scoping systematic review will be to identify and evaluate the range of air ambulance outcome measures reported in the literature and help to construct a quality dashboard based on a healthcare quality framework.MethodsWe will search PubMed, MEDLINE, CINAHL, Scopus, and Cochrane Database of Systematic Reviews (from January 2001 onwards). Complementary searches will be conducted in selected relevant journals. We will include systematic reviews and observational studies (cohort, cross-sectional, interrupted time series) in critically ill or injured patients published in English and focusing on air ambul...
Source: Systematic Reviews - April 2, 2020 Category: International Medicine & Public Health Source Type: research

Neuroimaging and analytical methods for studying the pathways from mild cognitive impairment to Alzheimer ’s disease: protocol for a rapid systematic review
The objective of the present study is to investigate the most recent neuroimaging procedures in the domain of prediction of transition from MCI to AD dementia for clinical applications and to systematically discuss the machine learning techniques used for the prediction of MCI conversion.MethodsElectronic databases including PubMed, SCOPUS, and Web of Science will be searched from January 1, 2017, to the date of search commencement to provide a rapid review of the most recent studies that have investigated the prediction of conversion from MCI to Alzheimer ’s using neuroimaging modalities in randomized trial or obser...
Source: Systematic Reviews - April 2, 2020 Category: International Medicine & Public Health Source Type: research

Extracranial-intracranial bypass surgery for occlusive atherosclerotic disease of the anterior cerebral circulation: protocol for a systematic review and meta-analysis
The objective of this study will be to compare the efficacy of and extracranial-intracranial bypass surgery with that of other medical therapy in adult patients with occlusive atherosclerotic disease of the anterior cerebral circulation.MethodsThis is the study protocol for a systematic review. We will search MEDLINE, EMBASE, Web of Science, and the Cochrane Library (from January 1980 onwards). We will include randomized controlled trials, quasi-experimental studies (non-randomized, interrupted time series), and observational studies (e.g., cohort studies and case-control studies), examining the efficacy of extracranial-in...
Source: Systematic Reviews - April 2, 2020 Category: International Medicine & Public Health Source Type: research