Mesenchymal stem cells for sensorineural hearing loss: protocol for a systematic review of preclinical studies
The objective of the proposed systematic review is to examine the efficacy of MSCs as a therapy for SNHL in animal models.MethodsWe will include preclinical animal studies of SNHL in which MSCs are administered, and outcomes are compared against MSC-na ïve controls. The primary outcome will include audiologic tests that are routinely used in experimental studies of hearing loss, such as auditory brainstem response (ABR) and distortion product otoacoustic emissions testing (DPOAE). Secondary outcomes will include histology, microscopy, gene protei n expression, and behavioral responses of animals. Electronic searches o...
Source: Systematic Reviews - May 25, 2019 Category: International Medicine & Public Health Source Type: research

Does stage of illness influence recovery-focused outcomes after psychological treatment in bipolar disorder? A systematic review protocol
DiscussionThis review will contribute to the literature by expanding upon previous reviews and potentially inform the psychosocial treatment of established BD. Implications include assisting clinicians, consumers and researchers to identify and select interventions most appropriate to recovery-focused goals based on individuals ’ clinical status.Systematic review registrationPROSPERO CRD42016037868 (Source: Systematic Reviews)
Source: Systematic Reviews - May 25, 2019 Category: International Medicine & Public Health Source Type: research

Psychological interventions for people with psychotic experiences: protocol for a systematic review and meta-analysis
DiscussionThe identification of effective psychological interventions and of specific components associated with intervention effectiveness will augment existing evidence that can inform the development of a new, tailored intervention to improve outcomes related to psychotic symptoms, anxiety and depression, distress, functioning, and quality of life.Systematic review registrationPROSPEROCRD42016033869 (Source: Systematic Reviews)
Source: Systematic Reviews - May 23, 2019 Category: International Medicine & Public Health Source Type: research

Decision aids that facilitate elements of shared decision making in chronic illnesses: a systematic review
ConclusionsDAs for selected chronic conditions are mostly designed to transfer information about options and their harms and benefits. The extent to which their support of SDM key elements relates to their impact on SDM outcomes could not be ascertained.Systematic review registrationPROSPERO registration number:CRD42016050320. (Source: Systematic Reviews)
Source: Systematic Reviews - May 20, 2019 Category: International Medicine & Public Health Source Type: research

Experiential learning for primary healthcare workers in low- and middle-income countries: a scoping review protocol
DiscussionWe anticipate finding a significant number of studies on the applications of experiential learning in resource-limited settings. Findings will be disseminated through publication in a peer-reviewed journal, peer presentations as well as presentations at relevant conferences. (Source: Systematic Reviews)
Source: Systematic Reviews - May 20, 2019 Category: International Medicine & Public Health Source Type: research

Epidemiology of hepatitis E virus infection in animals in Africa: a systematic review and meta-analysis  protocol
DiscussionHEV-infected animals are likely to transmit this virus to humans in Africa, as studies have already shown in developed countries. This systematic review and meta-analysis will provide a clear picture of the epidemiology of HEV in animals in Africa, to better understand this infection and to respond adequately to the epidemic challenges that often afflict Africa.Systematic review registrationPROSPERO,CRD42018087684. (Source: Systematic Reviews)
Source: Systematic Reviews - May 20, 2019 Category: International Medicine & Public Health Source Type: research

Epidemiology of respiratory viral infections in people with acute respiratory tract infections in Africa: the VARIAFRICA systematic review and meta-analysis protocol
DiscussionThis systematic review and meta-analysis is based on published data and therefore does not require ethical approval. This work will serve as a basis for the development of strategies for prevention and control ARTI in Africa and will also serve to identify data gaps and guide future investigations. The final report will be published in peer-reviewed journals as a scientific article and presented in workshops, conferences, and scientific conferences.Systematic review registrationPROSPERO,CRD42018088261. (Source: Systematic Reviews)
Source: Systematic Reviews - May 20, 2019 Category: International Medicine & Public Health Source Type: research

Experiential peer support and its effects on desistance from delinquent behavior: protocol paper for a systematic realist literature review
DiscussionInvestigating the effects and the underlying mechanisms of support by experiential peers for individuals with delinquent behavior is relevant because the forensic setting has some unique features, and the involvement of service users might create even more tension than in other settings due to stigma and perceived risks. The findings that will be reported in the realist review will contribute to the knowledge of the effects of support by experiential peers and will provide insight into which aspects remain to be studied. It might also provide formal care institutions with guidance on whether to involve experienti...
Source: Systematic Reviews - May 18, 2019 Category: International Medicine & Public Health Source Type: research

Using mobile phones to improve young people ’s sexual and reproductive health in low- and middle-income countries: a systematic review protocol to identify barriers, facilitators and reported interventions
DiscussionThe systematic review will assist researchers and SRH professionals in understanding facilitators and barriers to implementing and increasing the uptake of mHealth interventions for SRH in LMICs. Finally, this review will provide more detailed information about embracing the use of mobile phones at different levels of the healthcare system for improving young people ’s SRH outcomes.Systematic review registrationPROSPERO CRD42018087585 (Source: Systematic Reviews)
Source: Systematic Reviews - May 18, 2019 Category: International Medicine & Public Health Source Type: research

Anticonvulsants for behavioral and psychological symptoms in dementia: protocol for a systematic review
DiscussionThis is a protocol for a systematic review addressing the anticonvulsant group of medications as a whole, and as such, our results will inform current clinical practice in the use of anticonvulsants for BPSD. It will also help clinicians and policy makers compare the efficacy of anticonvulsants compared to antidepressants and antipsychotics as well as identify areas which will need further study.Systematic review registrationPROSPEROCRD42017079826 (Source: Systematic Reviews)
Source: Systematic Reviews - May 18, 2019 Category: International Medicine & Public Health Source Type: research

The effects of exercise on cardiometabolic outcomes in women with polycystic ovary syndrome not taking the oral contraceptive pill: protocol for a systematic review and meta-analysis
DiscussionA large proportion of women are affected by PCOS. It is prudent to examine how CVD risk can be mitigated in this high-risk population, and this review aims to provide evidence-driven recommendations on the types of exercise interventions that are effective for this. The review will seek to provide recommendations regarding type, frequency and duration of exercise interventions to improve cardiometabolic profile in PCOS. The subgroup analysis may be able to highlight difference in intervention effects between normo-androgenic and hyper-androgenic profile.Limitations include heterogeneity across studies and a scarc...
Source: Systematic Reviews - May 16, 2019 Category: International Medicine & Public Health Source Type: research

Predisposing and protective factors influencing suicide ideation, attempt, and death in patients accessing substance use treatment: a systematic review and meta-analysis protocol
DiscussionThis systematic review will contribute to our knowledge of risk and protective factors for suicidality in patients before and after treatment. Understanding these factors will help define areas of research for further investigation to ultimately inform risk assessment and prevention strategies.Systematic review registrationPROSPERO (reference number: CRD42018076260). (Source: Systematic Reviews)
Source: Systematic Reviews - May 15, 2019 Category: International Medicine & Public Health Source Type: research

Medication adherence influencing factors —an (updated) overview of systematic reviews
ConclusionThis overview analyses factors that might impact adherence to oral therapies in adult patients with physical chronic diseases. Our overview suggests that there is a social gradient in adherence. However, for most factors, the evidence was not conclusive due to the risk of bias, inconsistency or imprecision. (Source: Systematic Reviews)
Source: Systematic Reviews - May 10, 2019 Category: International Medicine & Public Health Source Type: research

Factors influencing perceptions of private water quality in North America: a systematic review
ConclusionsUnderstanding the factors that shape perceptions of water quality among private water users is an important step in developing private water management policies to increase compliance towards water testing and treatment in Canada and the USA. As many jurisdictions in Canada and the USA do not have mandatory private water testing or treatment guidelines, delineating these factors is an important step in informing future research and guiding policy on the public health of private water systems. (Source: Systematic Reviews)
Source: Systematic Reviews - May 10, 2019 Category: International Medicine & Public Health Source Type: research

Is a fusobacterium nucleatum infection in the colon a risk factor for colorectal cancer?: a systematic review and meta-analysis protocol
The objective of this systematic review is to synthesize the epidemiological evidence on the association between infection with Fusobacterium nucleatum in the colon and colorectal cancer.MethodsThis systematic review will include observational studies (cohort, case-control, cross-sectional) in humans in which the role of Fusobacterium nucleatum in the etiology of colorectal cancer was investigated. MEDLINE, EMBASE, Web of Science, and Cochrane Database of Systematic Reviews will be searched using a comprehensive search strategy and manual screening of references. Two reviewers will independently identify eligible studies a...
Source: Systematic Reviews - May 10, 2019 Category: International Medicine & Public Health Source Type: research

Effects of school-based interventions on motivation towards physical activity in children and adolescents: protocol for a systematic review
DiscussionIn order to increase and maintain physical activity levels in children and adolescents, motivation towards physical activity should be sustained. It is anticipated that the results of this systematic review will provide information as to which strategies implemented in the school setting are effective in increasing students ’ motivation towards physical activity, and hence increase their physical activity during school and after-school hours.Systematic review registrationPROSPERO CRD42018110306 (Source: Systematic Reviews)
Source: Systematic Reviews - May 10, 2019 Category: International Medicine & Public Health Source Type: research

Demographic and risk group heterogeneity across the UNAIDS 90-90-90 targets: a systematic review and meta-analysis protocol
DiscussionThe results of our review will help elucidate factors associated with failure to achieve virological suppression in sub-Saharan Africa, as well as factors associated with failure to achieve each of the 90-90-90 goals. These data will help quantify the population-level effects of current HIV treatment interventions to improve strategies for maximizing virological suppression and ending the HIV epidemic.Systematic review registrationPROSPEROCRD42018089505. (Source: Systematic Reviews)
Source: Systematic Reviews - May 6, 2019 Category: International Medicine & Public Health Source Type: research

Evaluation of the impact of single-nucleotide polymorphisms on treatment response, survival and toxicity with cytarabine and anthracyclines in patients with acute myeloid leukaemia: a systematic review protocol
DiscussionIt is expected that clinical decisions for AML patients will consider evidence-based practices to contribute to better patient management. In this way, we will be able to define how to treat patients with AML to improve their survival and quality of life.Systematic review registrationPROSPEROCRD42018100750 (Source: Systematic Reviews)
Source: Systematic Reviews - May 3, 2019 Category: International Medicine & Public Health Source Type: research

The effect of acute stress on salivary markers of inflammation: a systematic review protocol
DiscussionThis systematic review will synthesize the evidence regarding salivary markers of inflammation in response to acute stress. We anticipate variation across studies but hypothesize that salivary markers of inflammation will increase in response to acute stress. The evidence obtained for this study will help guide future research by providing guidelines for the design and measurement of studies assessing salivary inflammation in response to acute stress. Findings will be disseminated with a peer-reviewed manuscript and an international conference presentation. (Source: Systematic Reviews)
Source: Systematic Reviews - May 2, 2019 Category: International Medicine & Public Health Source Type: research

School factors related to the emotional wellbeing and resettlement outcomes of students from refugee backgrounds: protocol for a systematic review
DiscussionGiven the centrality of school in the daily lives of resettled refugee children, it is vital to assess the impact of school climate on the psychosocial wellbeing and resettlement trajectories of this population. This review will identify evidence-based school factors which support good mental health and resettlement outcomes for refugee students and make recommendations for translation of this knowledge into the school environment.Systematic review registrationPROSPERO CRD42017077570 (Source: Systematic Reviews)
Source: Systematic Reviews - April 30, 2019 Category: International Medicine & Public Health Source Type: research

Correction to: Systematic review and meta-analysis of diagnostic accuracy of detection of any level of diabetic retinopathy using digital retinal imaging
Following publication of the original article [1], the authors reported an error in Fig.  4 in the PDF version. Figure 4 is the duplicate image of Fig. 3 and the correct figure is missing. The authors would like to apologize for this error. The correct figure is shown below. (Source: Systematic Reviews)
Source: Systematic Reviews - April 30, 2019 Category: International Medicine & Public Health Source Type: research

The effects of aerobic, resistance, and meditative movement exercise on sleep in individuals with depression: protocol for a systematic review and network meta-analysis
DiscussionThis systematic review and network meta-analysis will provide a synthesis of the currently available evidence concerning the effects of aerobic, resistance, and meditative movement exercises on sleep in patients with unipolar depression. Thereby, we hope to accelerate the consolidation of evidence and inform decision-makers on potential benefits and harms.Systematic review registrationThe protocol has been registered at the International Prospective Register of Systematic Reviews (PROSPERO; registration number: CRD42019115705). (Source: Systematic Reviews)
Source: Systematic Reviews - April 26, 2019 Category: International Medicine & Public Health Source Type: research

Examining the mental health outcomes of peer-led school-based interventions on young people aged between 4 and 18  years old: a systematic review protocol
DiscussionThis systematic review will be the first to synthesise the global evidence on the mental health outcomes of peer-led interventions for children and adolescents in a school setting. It will analyse the available data in order to understand the role of these interventions in schools, inform future developers of peer support programmes and identify gaps in current research. This review will be of value to policy makers, health and education services, researchers and those involved in delivering peer support initiatives.Systematic review registrationPROSPERO CRD42018116243 (Source: Systematic Reviews)
Source: Systematic Reviews - April 26, 2019 Category: International Medicine & Public Health Source Type: research

Neonatal mortality in Ethiopia: a protocol for systematic review and meta-analysis
DiscussionThe result from this systematic review will inform and guide health policy planners and researchers on the burden, causes, and determinants of neonatal mortality in Ethiopia. To our knowledge, this is the first systematic review in Ethiopia. We will synthesise the findings to generate up-to-date knowledge on neonatal mortality in Ethiopia.Systematic review registrationPROSPERO-CRD42018099663 (Source: Systematic Reviews)
Source: Systematic Reviews - April 26, 2019 Category: International Medicine & Public Health Source Type: research

Communication strategies for rare cancers: a systematic review protocol
DiscussionDespite the broad topic and width of study type that will be considered, this review hopes to provide a reflective summary of the communication strategies available for people living with and working with rare cancer. It aims to reveal any gaps in the resources available, to contribute to the long-term improvement of diagnosis and management of rare cancers.Systematic review registrationPROSPERO CRD42018099784 (Source: Systematic Reviews)
Source: Systematic Reviews - April 23, 2019 Category: International Medicine & Public Health Source Type: research

Interventions for improved diabetes control and self-management among those experiencing homelessness: protocol for a mixed methods scoping review
DiscussionThose experiencing homelessness who also have diabetes often struggle to manage their chronic condition. When care is tailored to suit their needs, it is feasible that outcomes may be improved. By collating and synthesizing information from diverse organizations and jurisdictions, we hope to facilitate the sharing of knowledge with others who wish to provide this type of care. (Source: Systematic Reviews)
Source: Systematic Reviews - April 22, 2019 Category: International Medicine & Public Health Source Type: research

Effects of aerobic exercise on pain and disability in patients with non-specific chronic low back pain: a systematic review protocol
DiscussionThis systematic review will provide a synthesis of current evidence on the effects of aerobic exercise in patients with chronic low back pain on pain and disability outcomes. This information can help healthcare professionals in decision-making related to the use of aerobic exercise in patients with low back pain.Following the guidelines, this systematic review protocol was registered on the Prospective International Register of Systematic Reviews (PROSPERO) number CRD42017071945. (Source: Systematic Reviews)
Source: Systematic Reviews - April 22, 2019 Category: International Medicine & Public Health Source Type: research

Understanding patient engagement in health system decision-making: a co-designed scoping review
ConclusionsThe results of this scoping review demonstrate that an evidence base around programs to advance patient engagement is largely absent. An opportunity exists for further research to identify strategies and measures to support patient engagement in healthcare decision-making. (Source: Systematic Reviews)
Source: Systematic Reviews - April 18, 2019 Category: International Medicine & Public Health Source Type: research

Communication strategies in the prevention of type 2 and gestational diabetes in vulnerable groups: protocol for a scoping review
DiscussionThe results will be used to inform the National education and communication strategy on diabetes mellitus in Germany. In particular, the results will be discussed in focus groups of experts to develop recommendations for communication strategies.Systematic review registrationPROSPERO does not register scoping reviews. (Source: Systematic Reviews)
Source: Systematic Reviews - April 18, 2019 Category: International Medicine & Public Health Source Type: research

Direct oral anticoagulants in treatment of cerebral venous thrombosis: a systematic review protocol
DiscussionCurrent guidelines in the treatment of cerebral vein thrombosis dating back to 2011 from the American Heart Association/American Stroke Association endorse the utility of anticoagulation for the treatment of cerebral vein thrombosis; however, they did not support the use of direct oral anticoagulants. Updated guidelines from the European Stroke Organization, endorsed by the European Academy of Neurology in 2017, also refute utilization of direct oral anticoagulants due to a lack of evidence. There have been nearly 10  years of experience with direct oral anticoagulants in the treatment of venous thrombosis...
Source: Systematic Reviews - April 18, 2019 Category: International Medicine & Public Health Source Type: research

Individual patient data network meta-analysis using either restricted mean survival time difference or hazard ratios: is there a difference? A case study on locoregionally advanced nasopharyngeal carcinomas
ConclusionThe use of either HR or rmstD impacts the results of NMA. Given the sensitivity of HR to non-proportional hazards, this finding could have implications in terms of meta-analysis methodology. (Source: Systematic Reviews)
Source: Systematic Reviews - April 15, 2019 Category: International Medicine & Public Health Source Type: research

Influence of adjuvant antibiotics on fistula formation following incision and drainage of anorectal abscesses: a systematic review protocol
The objective of this review is to summarize the available evidence on the role of antibiotics following I&D of anorectal abscesses on fistula formation. Secondary objectives include determining if antibiotics are associated with morbidity, repeat presentation to the emergency department, and requirement for reoperation.Methods/designMEDLINE, EMBASE, CINAHL, Cochrane Central Registry of Controlled Trials,http://apps.who.int/trialsearch, andclinicaltrials.gov will be searched to identify published and ongoing unpublished interventional and observational studies evaluating the role of antibiotics post I&D on the inci...
Source: Systematic Reviews - April 15, 2019 Category: International Medicine & Public Health Source Type: research

Searching for health equity: validation of a search filter for ethnic and socioeconomic inequalities in transport
ConclusionsThe validated search strategy derived in this study facilitates the conduct of systematic reviews and other literature searches investigating whether the effects of interventions differ by ethnicity or socio-economic status and may be further developed in future for other equity-focused searches and reviews. (Source: Systematic Reviews)
Source: Systematic Reviews - April 11, 2019 Category: International Medicine & Public Health Source Type: research

Differential methylation in rare ophthalmic disorders: a systematic review protocol
DiscussionThis systematic review will enable us to identify if differential methylation can be used to characterise rare ophthalmic disease, which could have crucial implications for improving the accuracy and speed of diagnosis, identifying novel therapeutic targets to reduce or prevent vision loss and overall improving understanding of rare ophthalmic disease.Systematic review registrationPROSPERO CRD42018094231 (Source: Systematic Reviews)
Source: Systematic Reviews - April 10, 2019 Category: International Medicine & Public Health Source Type: research

Patient and family-initiated escalation of care: a qualitative systematic review protocol
DiscussionPatient- and family-initiated escalation of care schemes have been developed and implemented in several countries including the United  States, the United Kingdom and Australia, but there is limited evidence regarding patients’ or families’ perceptions of deterioration or the barriers and facilitators to using these schemes in practice, particularly in acute adult areas. This systematic review will provide evidence for the de velopment of a patient and family escalation of care scheme that can be tested in a feasibility study.Systematic review registrationPROSPEROCRD42018106952 (Source: Systematic Reviews)
Source: Systematic Reviews - April 9, 2019 Category: International Medicine & Public Health Source Type: research

The impact of income support systems on healthcare quality and functional capacity in workers with low back pain: a realist review protocol
DiscussionIncome support and healthcare systems are highly complex and fluid programmes. At the intersection between these systems are those with low back pain. By using realist review methods, we will provide explanatory rather than judgemental findings. The resulting multi-dimensional and contextual understanding of the impact of income support systems on important low back pain outcomes will provide valuable insight for future income support and healthcare policy development. (Source: Systematic Reviews)
Source: Systematic Reviews - April 9, 2019 Category: International Medicine & Public Health Source Type: research

Risk of bias judgements and strength of conclusions in meta-evidence from the Cochrane Colorectal Cancer Group
Conclusions were categorized as informing clinical practice (I) or not (N). Both I and N categories were divided into firm (F) or tempered (T) based on the definitiveness of their language. ROB judgements were aggregated. Reviews were classed as Medical (M), Surgical (S), Medical& Surgical (MS) or Other (O) based on their intervention, with O reviews then excluded. Data were analyzed in SPSS.ResultsNinety-five reviews were included, covering 1892 studies. Sixty-two percent (n = 59/95) informed clinical practice (I). Thirty-eight percent (n = 36/95) did not inform clinical practice (N). Of th...
Source: Systematic Reviews - April 8, 2019 Category: International Medicine & Public Health Source Type: research

Association between harm reduction strategies and healthcare utilization in patients on long-term prescribed opioid therapy presenting to acute healthcare settings: a protocol for a systematic review and meta-analysis
This study will better characterize harm reduction strategies for patients on long-term prescribed opioids presenting to acute healthcare settings. It will also add new knowledge and generate greater understanding of key knowledge gaps of the long-term prescribed opioid use and its impact on healthcare utilization.Systematic review registrationCRD42018088962. (Source: Systematic Reviews)
Source: Systematic Reviews - April 5, 2019 Category: International Medicine & Public Health Source Type: research

Seeking adverse effects in systematic reviews of orthodontic interventions: protocol for a cross-sectional study
This study will assess whether adverse effects were sought and whether findings related to adverse effects were reported in systematic reviews of orthodontic interventions in the five leading orthodontic journals and in the Cochrane Database of Systematic Reviews.MethodsSystematic reviews of clinical orthodontic interventions published between 01 August 2009 and 31 July 2019 in the five leading orthodontic journals and in the Cochrane Database will be included. Empty reviews will be excluded. The reporting of outcomes on adverse effects will not determine eligibility, i.e., reviews will not be excluded, because they did no...
Source: Systematic Reviews - April 5, 2019 Category: International Medicine & Public Health Source Type: research

Protocol for a systematic review, meta-analysis, and trial sequential analysis of clinical outcomes following accelerated versus conventional corneal collagen cross-linking for corneal ectasia
DiscussionThis review will provide a comprehensive evaluation of the evidence on accelerated and conventional CXL approaches and serve to inform clinical practice, medical device design, and future research. Evaluating variations of the CXL protocol aimed at reducing treatment duration is of critical importance and a prerequisite to expanding treatment availability to more patients.Systematic review registrationPROSPERO CRD42018104151 (Source: Systematic Reviews)
Source: Systematic Reviews - April 4, 2019 Category: International Medicine & Public Health Source Type: research

Addressing preconception behaviour change through mobile phone apps: a protocol for a systematic review and meta-analysis
DiscussionThis systematic review is the first to assess the effects of preconception mobile phone app behaviour change and educational interventions in improving future pregnancy and maternal and child outcomes, in women of reproductive age.Systematic review registrationPROSPERO 2017:CRD42017065903. (Source: Systematic Reviews)
Source: Systematic Reviews - April 4, 2019 Category: International Medicine & Public Health Source Type: research

Predicting repeated self-harm or suicide in adolescents and young adults using risk assessment scales/tools: a systematic review protocol
DiscussionThis systematic review will be the first to explore the use of assessment scales/tools in an adolescent population and will help to inform current practice regarding scales/tools with higher predictive ability. There is currently no evidence specifically for this population and a clear need with a high prevalence of self-harm and suicide in adolescents. Additionally, this review will help guide future research into suicide and self-harm prediction and prevention.Systematic review registrationPROSPEROCRD42017058686 (Source: Systematic Reviews)
Source: Systematic Reviews - April 4, 2019 Category: International Medicine & Public Health Source Type: research

Discharge communication practices in pediatric emergency care: a systematic review and narrative synthesis
ConclusionExisting literature examining discharge communication in pediatric emergency care varies widely. A theory-based approach to intervention design is needed to improve our understanding regarding discharge communication practice. Strengthening discharge communication in a pediatric emergency context presents a significant opportunity for improving parent comprehension and health outcomes for children.Systematic review registrationPROSPERO registration number: CRD42014007106. (Source: Systematic Reviews)
Source: Systematic Reviews - April 3, 2019 Category: International Medicine & Public Health Source Type: research

Protocol for a systematic review of time to antibiotics (TTA) in patients with fever and neutropenia during chemotherapy for cancer (FN) and interventions aiming to reduce TTA
This study aims to evaluate the association between TTA and patient-important clinical outcomes. Additionally, it will identify, critically appraise, and synthesise information on performed interventions and its effect to reduce TTA as a way of gaining insight into the potential use of these approaches. This will provide better knowledge for an adjusted treatment approach of FN.Systematic review registrationPROSPERO [CRD42018092948] (Source: Systematic Reviews)
Source: Systematic Reviews - April 3, 2019 Category: International Medicine & Public Health Source Type: research

Interventions to improve emergency department use for mental health reasons: protocol for a mixed-methods systematic review
DiscussionUsing a combined systematic review methodology and integrated knowledge translation plan, the project will provide decision makers with concrete evidence to support the implementation and evaluation of interventions to improve emergency department use for mental health reasons. These interventions reflect widespread priorities in the area of mental health care.Systematic review registrationPROSPEROCRD42018087430 (Source: Systematic Reviews)
Source: Systematic Reviews - April 3, 2019 Category: International Medicine & Public Health Source Type: research

Interventions for reducing and/or controlling domestic violence among pregnant women in low- and middle-income countries: a systematic review
DiscussionThis review attempted to address the knowledge gap by collating evidence on interventions aimed at addressing DV among pregnant women in LMICs. The development of a ToC was critical in understanding how certain activities led to the desired outcomes. This ToC can guide the design of future research and development of practice guidelines. The participatory involvement of the stakeholders is recommended to refine the current ToC to support its further development for practice.Systematic review registrationPROSPERO,CRD42017073938 (Source: Systematic Reviews)
Source: Systematic Reviews - April 2, 2019 Category: International Medicine & Public Health Source Type: research

The association between diabetes and age at the onset of menopause: a systematic review protocol
AbstractBackgroundAge at the onset of menopause is the most important determinant of women ’s future health outcomes. While the basic mechanisms contributing to the onset of menopause are still not fully understood, age at menopause depends on a complex set of various factors. In this regard, the effects of diabetes (DM I/II) on the age at the onset of menopause have received little att ention.Methods and analysisElectronic databases including PubMed/MEDLINE, Web of Science, Scopus, EMBASE, and Google Scholar will be searched for articles published during January 2000 to August 2018 and containing combinations of rel...
Source: Systematic Reviews - April 2, 2019 Category: International Medicine & Public Health Source Type: research

Well siblings ’ experiences of living with a child following a traumatic brain injury: a systematic review protocol
DiscussionIt is anticipated that the findings of the proposed review will be of interest to health and social care professionals, particularly those working in units where children have suffered TBIs, their well siblings, and families. The aim is to identify well siblings ’ experiences which can inform enhanced care delivery to the families of children following a TBI. The findings of this review will provide evidence to aid professionals with the assessment of siblings’ needs to enhance their sense of self within the family unit. Future directions, in addition t o potential limitations of the approach, will be...
Source: Systematic Reviews - April 2, 2019 Category: International Medicine & Public Health Source Type: research

Patient prioritization tools and their effectiveness in non-emergency healthcare services: a systematic review protocol
DiscussionThis systematic review will provide much-needed knowledge regarding patient prioritization tools. The results will benefit clinicians, decision-makers, and researchers by giving them a better understanding of the methods used to prioritize patients in clinical settings.Systematic review registrationPROSPEROCRD42018107205 (Source: Systematic Reviews)
Source: Systematic Reviews - March 30, 2019 Category: International Medicine & Public Health Source Type: research

Feasibility, acceptability, and effectiveness of young people-specific, integrated out-of-hospital services: a protocol for a systematic review
DiscussionThis review aims to provide comprehensive evidence regarding young people-specific integrated out-of-hospital health services. Such rigorously evaluated evidence will be useful for policy makers and health professionals to design and select health services for this group. This review will also identify any evidence gaps in young people-specific integrated health services evaluation.Systematic review registrationPROSPEROCRD42017068836 (Source: Systematic Reviews)
Source: Systematic Reviews - March 28, 2019 Category: International Medicine & Public Health Source Type: research