Observational study of post-operative pain control before and after the implementation of a clinical practice guideline for postoperative pain management.
The objective of this study was to evaluate the prevalence and intensity of postoperative pain and analgesic norms, before and after the implementation of a CPGPP. MATERIAL AND METHOD: An observational study was carried out that included 2cross-sectional studies in 2separate periods, before and after implementation of the CPGPP. Adult patients postoperated on the first day of admission in the surgery plants were included. Demographic, clinical and pharmacological variables were collected from clinical histories. The intensity of the pain was collected through individual interviews with patients. RESULTS: We include...
Source: Medicina Clinica - April 18, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Effectiveness of ivacaftor in cystic fibrosis: Improvement of liver cirrhosis, nutritional status and respiratory function.
Authors: Martín de Vicente C, García Romero R PMID: 30982531 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 17, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Polypharmacy: Something more than just numbers.
Authors: Blanco Reina E, Valdellós J PMID: 30982532 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 17, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Massive deep venous thrombosis in a patient addicted to cocaine.
Authors: Losno RA, Milisenda JC, Aibar J PMID: 30982533 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 17, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Gastritis enfisematosa: una rara imagen.
Authors: Salgueiro Marques A, Niza Barradas J, Nogueira D PMID: 30982534 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 17, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Cystic pancreatic lesions. Origin and historical evolution.
Authors: Navarro S PMID: 30979511 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 15, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Towards the definition of Sepsis-4: Diagnostic and prognostic power of biomarkers to improve the management of sepsis in the emergency department.
Authors: Julián-Jiménez A, Supino M, Loro Chero L, en nombre del Grupo de Trabajo Latinoamericano para la mejora de la atención del paciente con Infección en Urgencias (GT-LATINFURG) PMID: 30979512 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 15, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Bacteremia by Nocardia farcinica.
Authors: Rodríguez Fernández L, Martín Guerra JM, Gil González I PMID: 30981434 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 15, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Biosimilar drugs: Measures to promote their use.
Authors: Guiu Segura JM, Gilabert Perramon A PMID: 30981435 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 15, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Down syndrome: Current incidence and comorbidities.
Authors: Gutiérrez Sánchez AM, Marín Andrés M, de Arriba Muñoz A PMID: 30981436 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 15, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Clostridium difficile infection in oncohematologic patients.
Authors: Sánchez-Muñoz LA, Rodríguez-Fernández L, Zapico-Aldea G PMID: 30981437 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 15, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Iatrogenic hyperthyroidism can be a triggering factor for takotsubo cardiomyopathy.
Authors: Cervilla-Muñoz E, Bringas-Beranek M, Demelo-Rodríguez P PMID: 30975499 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 14, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Guillain-Barr é syndrome after viral hepatitis A.
Guillain-Barré syndrome after viral hepatitis A. Med Clin (Barc). 2019 Apr 07;: Authors: López Ruiz R, Dotor García-Soto J, Eichau S PMID: 30971337 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 12, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Influence of gender, age and residence altitude on haemoglobin levels and the prevalence of anaemia.
CONCLUSIONS: We obtained data from sub-populations that were previously not well described; anaemia in the elderly requires consideration. The influence of altitude does not seem to be fully considered within the correction framework proposed by WHO. Broader studies should be planned in order to obtain adequate parameters for the elderly and residents at high altitudes in Spain, as both groups represent an important proportion of the population, to avoid potential underdiagnosis of anaemia and overdiagnosis of other pathologies. PMID: 30954290 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 9, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Vertebral artery dissection secondary to hangman's fracture.
Authors: Láinez Ramos-Bossini AJ, Gálvez López R, Pastor Rull J PMID: 30954291 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 9, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Scoping reviews. Another way of literature review.
Authors: Ruiz-Perez I, Petrova D PMID: 30954292 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 9, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Incidence and mortality of osteomielitis in Spain according to the basic minimum data set.
CONCLUSIONS: The incidence of hospitalisations for osteomyelitis in Spain is substantial. Sepsis, being over 64 and MRSA infection are important risk factors for death. PMID: 30954293 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 9, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Comparison between PROFUND and PALIAR indexes in polypathological patients with advanced non-oncologic chronic diseases.
Authors: Díez-Manglano J, Gómez-Aguirre N, Velilla-Marco J, Lambán Aranda MP, de Escalante Yangüela B, Fuertes Ruiz D, García Aranda A, Clemente Sarasa C, en nombre de los investigadores del estudio PALIARAGON, Lista de investigadores del estudio PALIARAGON Abstract BACKGROUND AND OBJECTIVE: To compare the discrimination power of PROFUND and PALIAR indexes for predicting mortality in polypathological patients with advanced non-oncologic chronic disease. MATERIAL AND METHODS: Prospective multicentre cohort study. We included polypathological patients with advanced non-oncologic c...
Source: Medicina Clinica - April 2, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Reclassification by applying the Framingham equation 30 years to subjects with intermediate cardiovascular risk. MARK study.
Authors: Gomez-Sanchez L, Gomez-Marcos MA, Patino-Alonso MC, Recio-Rodriguez JI, Gomez-Sanchez M, González-Sánchez J, Alonso-Domínguez R, Sánchez-Aguadero N, Maderuelo-Fernandez JA, Ramos R, Garcia-Ortiz L, Rodriguez-Sanchez E, MARK Group Abstract BACKGROUND AND OBJECTIVE: The estimation of cardiovascular risk (CVR) with scores at 30 years old has a special interest in reclassifying in a suitable way
Source: Medicina Clinica - April 2, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Gynaecological and obstetrical bleeding in Caucasian women with congenital factor XI deficiency: Results from a twenty-year, retrospective, observational study.
CONCLUSION: Women with FXI deficiency, especially those with a positive history of bleeding or FXI:C ≤43.5%, are at risk of developing gynaecological/obstetrical haemorrhages, most of them mild/moderate. Systematic prophylaxis has questionable effectiveness, but might cause severe side effects. PMID: 30926156 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 1, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Effectiveness of umbilical cord mesenchymal stem cells in patients with critical limb ischemia.
CONCLUSIONS: This study demonstrates that UC-MSCs have anti-inflammatory and immunomodulation properties in CLI and suggests that UC-MSCs promote healing of non-healing wounds. PMID: 30926157 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - April 1, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Directed to consumer genetic testing. Perspective from the Ethics commission of the Spanish Society for Human Genetics.
Authors: Pàmpols Ros T, García Sagredo JM, Pérez Aytés A, Díaz de Bustamante A PMID: 30898448 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 23, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Total and cardiovascular mortality risk according to KDIGO guidelines classification in type 2 diabetic patients.
Authors: Medrano Navarro AL, Justel Enríquez A, Alameda Serrano J, Blasco Lamarca Y, Sáenz Abad D, Gimeno Orna JA Abstract BACKGROUND AND AIMS: Our aim was to assess the usefulness of KDIGO 2012 risk classification to predict total and cardiovascular mortality in type 2 diabetes mellitus (DM2). MATERIAL AND METHODS: Prospective cohort study that included DM2 patients. Clinical end-points were total and cardiovascular mortality. The main predictive variable was KDIGO risk classification, which is a combination of urinary albumin excretion and glomerular filtration rate. The predictive value was eva...
Source: Medicina Clinica - March 20, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Musical stimulus in hospitalized patients with dementia.
Authors: Álvarez Gómez E, Minthe MB, Cánovas Pareja C PMID: 30878188 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 19, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Tumor thrombosis in right inferior pulmonary vein due to chondrosarcoma metastasis and systemic embolism.
Authors: Varona Porres D, Sánchez AL, Persiva Ó, Pallisa E PMID: 30871821 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 16, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Thrombotic thrombocytopenic purpura in a patient with metastatic lung cancer.
Authors: Doello K, Amezcua V, Delgado A PMID: 30871822 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 16, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Reversible encephalopathy syndrome in acute porphyria attack.
Authors: Losno RA, Combalia A, Aguilera P PMID: 30871823 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 16, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Pneumocystis jirovecii pneumonia prophylaxis in immunocompromised patients with systemic autoimmune diseases.
The objective of this review is to analyze the available data on the incidence of PcP and the effect of PcP prophylaxis in patients with autoimmune diseases that may be useful in clinical practice. PMID: 30853123 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 13, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Characteristics and outcome of patients with solid tumour requiring admission to the intensive care unit. Usefulness of three severity score systems.
Authors: Pérez Pérez ML, Gonzaga López A, Balandín Moreno B, Maximiano Alonso C, Palacios Castañeda D, Ferreres Franco J, García Sanz J, Villanueva Fernández H, Valdivia de la Fuente M, Ortega López A, Alcántara Carmona S, Pérez Redondo M, Royuela Vicente A Abstract BACKGROUND AND OBJECTIVE: To describe the characteristics and the evolution of patients with solid tumours admitted to the ICU and to identify factors associated with hospital mortality and to evaluate three illness severity scores. MATERIAL AND METHODS: Descriptive study includin...
Source: Medicina Clinica - March 13, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Allogeneic stem cell transplantation  in the era of novel therapies for acute lymphoblastic leukaemia.
This article reviews the indications of allo-HCT for children and adults diagnosed with ALL, the different sources and conditioning regimens for transplantation as well as the role of measurable residual diseases pre- and post-HCT in the era of the new therapies for ALL. PMID: 30857792 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 13, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Role of antiplatelet therapy in the development of intracranial bleeding after mild traumatic brain injury.
Authors: Genebat González M, Dusseck Brutus R, García-Olloqui Á, García-Delgado Rosado H, Bellido Alba R, Pérez Torres I Abstract INTRODUCTION AND OBJECTIVE: The use of antiplatelet agents is increasing, mainly in elderly patients in whom cranial trauma is a frequent reason for consultation to the emergency department. In this context, discordances have been described regarding the increased risk of post-traumatic injury that involves taking antiplatelet drugs. Therefore, the objective of this present study was to analyse factors associated with intracranial bleeding after mild br...
Source: Medicina Clinica - March 13, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Robotics in medicine.
Authors: Barrientos A, Del Cerro J PMID: 30857794 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 13, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Impact of the MMR vaccine on the incidence of mumps in the Community of Madrid and evaluation of the effectiveness of the Jeryl-Lynn strain. Years 1998-2016.
CONCLUSIONS: Parotiditis behavior is characterised by fluctuations, changes in presentation and a decrease in VE. PMID: 30857795 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 13, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

A multidisciplinary approach for patients with multiple chronic conditions: IMPACTO study.
The objective of the study was to evaluate the effects of a multidisciplinary intervention on the outcomes of polypathological patients (PP). METHODS: A multicenter quasi-experimental pre-post study with a 12-month follow up was performed. In-hospital, at discharge and outpatient clinics patients who met criteria of PP between March 2012 and October 2013 were included. The multidisciplinary approach was defined by 11 interventions performed by general practitioners, internal medicine physicians, team care nurses and hospital pharmacists. The primary outcome was reduction in the number of hospital admissions and days of...
Source: Medicina Clinica - March 13, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Fran ḱs sign and chest pain.
Franḱs sign and chest pain. Med Clin (Barc). 2019 Mar 08;: Authors: Ramírez Montesinos R, Duran Taberna M, Torres Quilis C PMID: 30857797 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 13, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Critical limb ischemia in the very elderly patients: A growing problem.
Authors: Castilla-Guerra L, Montero García I, Rico Corral MA PMID: 30857798 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 13, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Long-term outcomes after percutaneous atrial septal deffects clossure.
Authors: Lapeña-Reguero M, Rueda-Nuñez F, Álvarez-García N PMID: 30857799 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 13, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Hipoglucemia secondary to hyperinsulinism in a patient with congenital long QT syndrome.
Authors: Salamanca Zarzuela B, Alcalde Martín C, Centeno Malfaz F PMID: 30850170 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 10, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Disseminated nocardiosis secondary to Nocardia otitidiscaviarum infection with fatal outcome.
Authors: Paniagua-García M, Palacios-Baena ZR, Del Toro López MD PMID: 30850171 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 10, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Perivascular epitheliod cell tumors: Study of three gynecological cases.
DISCUSSION: Given the scarcity of cases, the literature consists of case reports and mini-reviews. Some authors have categorized the PEComas based on prognostic factors, but there is no agreement regarding the follow-up and treatment. 18F-FDG-PET/CT can help characterize these lesions. The surgery is the standard. In recurrent or malignant cases, there is a lack of evidence regarding chemotherapy and radiotherapy. New therapies with inhibitory m-TOR open a hopeful therapeutic window. PMID: 30827678 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 6, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Chronic infectious osteomyelitis: A diagnosis beyond the skin.
Authors: García Harana C, Del Boz González J, Padilla España L PMID: 30824262 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 5, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Is moderate alcohol consumption healthy? The evolution of evidence.
Authors: Zuluaga P, Colom J PMID: 30808503 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - March 1, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Clinical profile and associated factors of pulmonary involvement in primary Sj ögren's syndrome.
Clinical profile and associated factors of pulmonary involvement in primary Sjögren's syndrome. Med Clin (Barc). 2019 Feb 23;: Authors: Jin Y, Zhang T, Ye W, Zhu X, Wang L, Wang X Abstract OBJECTIVES: The aim of this study is to identify the clinical characteristics of primary Sjögren's syndrome (PSS) patients with pulmonary involvement and the associated factors for pulmonary involvement in PSS. METHODS: We retrospectively reviewed clinical features, laboratory examinations, imaging tests, pathological results and therapeutic strategy of 367 PSS patients. Comparisons were made between tw...
Source: Medicina Clinica - March 1, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Cardiovascular complications of methamphetamines: Study of 6 cases.
Authors: Santuré Sinfreu A, Buil Arasanz ME, Esparza Siegel L PMID: 30803793 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - February 27, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Direct oral anticoagulants for the treatment of venous thromboembolism in patients with cancer.
Authors: Franco Moreno AI, Cabezón Gutiérrez L, García Navarro MJ PMID: 30803794 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - February 27, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Cardiac tamponade and right ventricle perforation after an acupuncture procedure.
Authors: Llamas Fuentes R, Valle Alonso J, Turegano Cisneros JM PMID: 30803795 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - February 27, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Update in status epilepticus.
Authors: Santamarina E, Abraira L, Toledo M Abstract Status epilepticus (SE) is a neurological emergency that requires urgent antiepileptic therapies, and a rapid treatment of its cause. In recent years, its definition has been updated to adapt it to all types of SE; this update helps to standardise the treatment. The new definition is based on two times: point t1, after which the event will not spontaneously cease, and period t2, after which neuronal damage may appear. There are three lines of treatment: first, benzodiazepines; second, antiepileptic drugs; and third, intravenous anaesthetics. The application of th...
Source: Medicina Clinica - February 27, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Endometriosis: Diagnosis and treatment.
Authors: Lete I PMID: 30803797 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - February 27, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Prevalence of polypharmacy and associated factors in older adults in Spain: Data from the National Health Survey 2017.
CONCLUSIONS: the prevalence of polypharmacy in the elderly in primary care continues to increase and could be widely underestimated. In addition to multimorbidity, factors such as functional capacity or geriatric syndromes, fundamental in elderly people, modulate the habits of consumption and prescription of drugs in this population. PMID: 30803798 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - February 27, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research

Efficacy of mefloquine and mirtazapine on progressive multifocal leukoencephalopathy in a patient with peripheral T-cell lymphoma.
Authors: Peña M, Presas-Rodríguez S, Ribera JM PMID: 30803799 [PubMed - as supplied by publisher] (Source: Medicina Clinica)
Source: Medicina Clinica - February 27, 2019 Category: General Medicine Tags: Med Clin (Barc) Source Type: research