Immunotherapy in multiple myeloma
Med Clin (Barc). 2024 Jan 12:S0025-7753(23)00753-4. doi: 10.1016/j.medcli.2023.11.019. Online ahead of print.ABSTRACTPatients with multiple myeloma who present with refractory disease or relapse after receiving the main classes of available drugs -immunomodulators, proteasome inhibitors and antibodies against CD38- do not have satisfactory therapeutic alternatives. New treatments based on the redirection of T lymphocytes to act directly against tumor cells, such as bispecific antibodies and T cells with chimeric antigen receptors, are changing this scenario. The published information confirms unprecedented antitumor activi...
Source: Medicina Clinica - January 13, 2024 Category: General Medicine Authors: Pedro Asensi Cant ó Mario Arnao Herraiz Javier de la Rubia Comos Source Type: research

Substance use disorder: Epidemiology, medical consequences and treatment
Med Clin (Barc). 2024 Jan 12:S0025-7753(23)00750-9. doi: 10.1016/j.medcli.2023.11.016. Online ahead of print.ABSTRACTSubstance use is a common health problem, and substance use disorder, which is its most severe presentation, is associated with multiple medical consequences and a negative impact on individual and on population health. Substance use disorder needs to be addressed as any chronic medical condition; therefore, it has to be detected at the early stages and has to be properly treated to prevent drug-related harm. Internists should be able to recognize and treat intoxication and abstinence. Internists should also...
Source: Medicina Clinica - January 13, 2024 Category: General Medicine Authors: Daniel Fuster Paola Zuluaga Robert Muga Source Type: research

Innovative use of telitacicept in Ehlers-Danlos syndrome
Med Clin (Barc). 2024 Feb 9;162(3):141-142. doi: 10.1016/j.medcli.2023.06.043. Epub 2024 Jan 11.NO ABSTRACTPMID:38216394 | DOI:10.1016/j.medcli.2023.06.043 (Source: Medicina Clinica)
Source: Medicina Clinica - January 12, 2024 Category: General Medicine Authors: Yanzao Zhao Jie Chen Anji Xiong Source Type: research

Minimally invasive offloading osteotomy in the treatment of diabetic foot ulcer: Analysis of 25 patients
CONCLUSIONS: Minimally invasive offloading osteotomy is a technically simple intervention, which presents a high success rate with minimal complications in our series.PMID:38216395 | DOI:10.1016/j.medcli.2023.11.024 (Source: Medicina Clinica)
Source: Medicina Clinica - January 12, 2024 Category: General Medicine Authors: Jos é Vicente Gil Boix Melchor Llad ó Vidal Elena Mena Ribas Jordi Viad é Julià Francisco Javier Fanjul Losa Santiago Tof é Povedano Source Type: research

Shrinking lung syndrome in systemic lupus erythematosus: A study of 9 patients
CONCLUSIONS: SLS should be considered in every lupus patient with unexplained dyspnea. Although it often shows improvement, many cases experience persistent deterioration despite treatment.PMID:38195280 | DOI:10.1016/j.medcli.2023.10.023 (Source: Medicina Clinica)
Source: Medicina Clinica - January 9, 2024 Category: General Medicine Authors: Alberto Casey Juan I Enghelmayer Cora G Legarreta Ana Mar ía Berón Mar ía Marta Perín Diana Dubinsky Source Type: research

Evolution of smoking prevalence in Spain and its 17 autonomous regions (1987-2020)
CONCLUSIONS: The number of men and women smokers has decreased in Spain between 1987-2020. Different patterns of evolution of the prevalence of consumption are observed among the ARs, especially among women. This reinforces the need for policies adapted to more local contexts and that take into account the gender perspective.PMID:38184463 | DOI:10.1016/j.medcli.2023.11.015 (Source: Medicina Clinica)
Source: Medicina Clinica - January 6, 2024 Category: General Medicine Authors: Julia Rey-Brandariz Alberto Ruano-Ravina Mar ía Isolina Santiago-Pérez Leonor Varela-Lema Carla Guerra-Tort Agust ín Montes Mar ía Piñeiro Carlos R ábade M ónica Pérez-Ríos Source Type: research

Permethrin-resistant scabies
Med Clin (Barc). 2024 Jan 5:S0025-7753(23)00712-1. doi: 10.1016/j.medcli.2023.11.012. Online ahead of print.NO ABSTRACTPMID:38184464 | DOI:10.1016/j.medcli.2023.11.012 (Source: Medicina Clinica)
Source: Medicina Clinica - January 6, 2024 Category: General Medicine Authors: Mar Luque-Luna Llu ís Corbella-Bagot Priscila Giavedoni Source Type: research

Evolution of smoking prevalence in Spain and its 17 autonomous regions (1987-2020)
CONCLUSIONS: The number of men and women smokers has decreased in Spain between 1987-2020. Different patterns of evolution of the prevalence of consumption are observed among the ARs, especially among women. This reinforces the need for policies adapted to more local contexts and that take into account the gender perspective.PMID:38184463 | DOI:10.1016/j.medcli.2023.11.015 (Source: Medicina Clinica)
Source: Medicina Clinica - January 6, 2024 Category: General Medicine Authors: Julia Rey-Brandariz Alberto Ruano-Ravina Mar ía Isolina Santiago-Pérez Leonor Varela-Lema Carla Guerra-Tort Agust ín Montes Mar ía Piñeiro Carlos R ábade M ónica Pérez-Ríos Source Type: research

Permethrin-resistant scabies
Med Clin (Barc). 2024 Jan 5:S0025-7753(23)00712-1. doi: 10.1016/j.medcli.2023.11.012. Online ahead of print.NO ABSTRACTPMID:38184464 | DOI:10.1016/j.medcli.2023.11.012 (Source: Medicina Clinica)
Source: Medicina Clinica - January 6, 2024 Category: General Medicine Authors: Mar Luque-Luna Llu ís Corbella-Bagot Priscila Giavedoni Source Type: research

Evolution of smoking prevalence in Spain and its 17 autonomous regions (1987-2020)
CONCLUSIONS: The number of men and women smokers has decreased in Spain between 1987-2020. Different patterns of evolution of the prevalence of consumption are observed among the ARs, especially among women. This reinforces the need for policies adapted to more local contexts and that take into account the gender perspective.PMID:38184463 | DOI:10.1016/j.medcli.2023.11.015 (Source: Medicina Clinica)
Source: Medicina Clinica - January 6, 2024 Category: General Medicine Authors: Julia Rey-Brandariz Alberto Ruano-Ravina Mar ía Isolina Santiago-Pérez Leonor Varela-Lema Carla Guerra-Tort Agust ín Montes Mar ía Piñeiro Carlos R ábade M ónica Pérez-Ríos Source Type: research

Permethrin-resistant scabies
Med Clin (Barc). 2024 Jan 5:S0025-7753(23)00712-1. doi: 10.1016/j.medcli.2023.11.012. Online ahead of print.NO ABSTRACTPMID:38184464 | DOI:10.1016/j.medcli.2023.11.012 (Source: Medicina Clinica)
Source: Medicina Clinica - January 6, 2024 Category: General Medicine Authors: Mar Luque-Luna Llu ís Corbella-Bagot Priscila Giavedoni Source Type: research

Retrospective analysis of venlafaxine-induced hypoglycemia in patients with overdose
CONCLUSIONS: The detection of hypoglycemia in a VLX overdose case is a readily available marker to suspect the severity of the patient. In any case, serum concentrations when available allow us to confirm intoxication.PMID:38182480 | DOI:10.1016/j.medcli.2023.11.002 (Source: Medicina Clinica)
Source: Medicina Clinica - January 5, 2024 Category: General Medicine Authors: Isabel Gomila Mu ñiz Lorenzo Socias Cresp í Jordi Puiguriguer Ferrando Alexandra M Guiu Marti Miguel Ángel Elorza Guerrero Bernardino Barcel ó Martín Source Type: research

Impact of Mediterranean diet in lowering risk of gestational diabetes mellitus: A cross-sectional study
CONCLUSIONS: Nearly two-fifths of pregnant women were diagnosed with GDM while only one-fourth complied with a Mediterranean diet. The increase in the frequency of GDM should be carefully monitored. It may be useful to detect risky pregnant women at the time of the first diagnosis, to measure their glucose levels, and to give suggestions about the Mediterranean diet in the early period.PMID:38161077 | DOI:10.1016/j.medcli.2023.11.010 (Source: Medicina Clinica)
Source: Medicina Clinica - December 31, 2023 Category: General Medicine Authors: Tu ğçe Odabaş Ozan Odaba ş Reci Meseri Source Type: research

The value of vaccines in the 21st century
Med Clin (Barc). 2023 Dec 30:S0025-7753(23)00709-1. doi: 10.1016/j.medcli.2023.10.025. Online ahead of print.NO ABSTRACTPMID:38161078 | DOI:10.1016/j.medcli.2023.10.025 (Source: Medicina Clinica)
Source: Medicina Clinica - December 31, 2023 Category: General Medicine Authors: Irma Casas Karen Colmenares Beatriz Blanco Julia Valera Source Type: research