The Association of Ovarian Reserve with Exposure to Bisphenol A and Phthalate in Reproductive-aged Women.
In this study, we evaluated exposure to EDCs associated with diminished ovarian reserve (DOR) and gynecologic health risks. METHODS: This cross-sectional study was performed from September 2014 to November 2014 and included 307 Korean reproductive-aged women. Anthropometric measurements, laboratory tests with urine and blood sampling and pelvic ultrasound examinations were performed. RESULTS: Urinary bisphenol A (BLA) level was significantly higher in the DOR group with anti-Müllerian hormone lower than 25 percentile (1.89 ± 2.17 ug/g and 1.58 ± 1.08 ug/g, P
Source: J Korean Med Sci - January 11, 2021 Category: General Medicine Authors: Park SY, Jeon JH, Jeong K, Chung HW, Lee H, Sung YA, Ye S, Ha EH Tags: J Korean Med Sci Source Type: research

Process of Obtaining Social Consensus and 3-Year Functional Outcomes of the First Hand Allotransplantation in Korea.
CONCLUSIONS: Hand transplantation at the distal forearm shows very satisfactory outcomes in functional, aesthetical, and psychological aspects. Legal and financial barriers against hand transplantation have long been the most burdensome issues. Despite this momentous success, there have been no other clinical applications of vascularized composite allotransplantation due to the limited acceptance by Korean doctors and people. Further public education campaigns for vascularized composite allotransplantation are needed to increase awareness and acceptance. PMID: 33429470 [PubMed - as supplied by publisher] (Source: J Korean Med Sci)
Source: J Korean Med Sci - January 11, 2021 Category: General Medicine Authors: Woo SH, Kim YW, Cheon HJ, Jang S, Do JY, Choi JH, Kang DH, Nam HJ, Yoo MJ, Lee YS, Choi JH Tags: J Korean Med Sci Source Type: research

Rapid Response System Should Be Enhanced at Non-general Ward Locations: a Retrospective Multicenter Cohort Study in Korea.
This study aimed to compare the clinical characteristics and outcomes of patients with RRS activation in non-GW locations and in the GW. METHODS: From January 2016 to December 2017, all patients requiring RRS activation in nine South Korean hospitals were retrospectively enrolled and classified according to RRS activation location: GW vs non-GW RRS activations. RESULTS: In total, 12,793 patients were enrolled; 222 (1.7%) were non-GW RRS activations. There were more instances of shock (11.6% vs. 18.5%) and cardiac arrest (2.7% vs. 22.5%) in non-GW RRS activation patients. These patients also had a lower oxygen sat...
Source: J Korean Med Sci - January 11, 2021 Category: General Medicine Authors: Kang BJ, Hong SB, Jeon K, Lee SM, Lee DH, Moon JY, Lee YJ, Kim JS, Park J, Ahn JJ Tags: J Korean Med Sci Source Type: research

Spatio-temporal Analysis of District-level Life Expectancy from 2004 to 2017 in Korea.
CONCLUSION: In this study, we estimated the annual district-level life expectancy from 2004 to 2017 in Korea by gender using a spatio-temporal model. Local governments could use annual district-level life expectancy estimates as a performance indicator of health policies to improve the health of local residents. The approach to district-level analysis with spatio-temporal modeling employed in this study could be used in future analyses to produce district-level health-related indicators in Korea. PMID: 33429472 [PubMed - as supplied by publisher] (Source: J Korean Med Sci)
Source: J Korean Med Sci - January 11, 2021 Category: General Medicine Authors: Lim HK, Kang HY, Kim I, Khang YH Tags: J Korean Med Sci Source Type: research

Symptoms and Characteristics Which Require Attention During COVID-19 Screening at a Port of Entry.
CONCLUSION: If overseas travelers experience loss of smell or taste in the two weeks prior to arrival, they may require an immediate examination to rule out COVID-19 at a port of entry. As to measure body temperature upon arrival at a port of entry, it is important to screen for any occurrence of fever within the two weeks prior to travel. Also, information with epidemiological relevance, such as recent contact with an individual suffering from any respiratory symptoms or with confirmed COVID-19, should be included in COVID-19 screening questionnaires for international travelers. PMID: 33429473 [PubMed - as supplied b...
Source: J Korean Med Sci - January 11, 2021 Category: General Medicine Authors: Song SW, Kim D, Park JY, Lee S Tags: J Korean Med Sci Source Type: research

Impact of Cardiovascular Risk Factors and Cardiovascular Diseases on Outcomes in Patients Hospitalized with COVID-19 in Daegu Metropolitan City.
Abstract BACKGROUND: Data regarding the association between preexisting cardiovascular risk factors (CVRFs) and cardiovascular diseases (CVDs) and the outcomes of patients requiring hospitalization for coronavirus disease 2019 (COVID-19) are limited. Therefore, the aim of this study was to investigate the impact of preexisting CVRFs or CVDs on the outcomes of patients with COVID-19 hospitalized in a Korean healthcare system. METHODS: Patients with COVID-19 admitted to 10 hospitals in Daegu Metropolitan City, Korea, were examined. All sequentially hospitalized patients between February 15, 2020, and April 24, ...
Source: J Korean Med Sci - January 11, 2021 Category: General Medicine Authors: Park BE, Lee JH, Park HK, Kim HN, Jang SY, Bae MH, Yang DH, Park HS, Cho Y, Lee BY, Nam CW, Lee JB, Kim U, Chae SC, Daegu COVID-19 Research Project Tags: J Korean Med Sci Source Type: research

Clinical Pathway for Emergency Brain Surgery during COVID-19 Pandemic and Its Impact on Clinical Outcomes.
We described a clinical pathway for patients who needed emergency brain surgery and determined whether differences in the surgery preparation process caused by COVID-19 screening affected clinical outcomes. METHODS: During the COVID-19 period, patients in need of emergency brain surgery in our institution were managed using a novel standardized pathway designed for COVID-19 screening. We conducted a retrospective review of patients who were hospitalized through the emergency room and underwent emergency brain surgery. A total of 32 patients who underwent emergency brain surgery from February 1 to June 30, 2020 were in...
Source: J Korean Med Sci - January 11, 2021 Category: General Medicine Authors: Lee SH, Jang JS, Chung JW, Kwon JT, Park YS Tags: J Korean Med Sci Source Type: research

The Importance of Early Recognition, Timely Management, and the Role of Healthcare Providers in Multisystem Inflammatory Syndrome in Children.
Abstract In April 2020, a pediatric report of an unusual inflammatory illness associated with coronavirus disease 2019 (COVID-19) led to similar cases in Europe and North America, which was referred to as multisystem inflammatory syndrome in children (MIS-C). Herein, we describe the case of a 12-year-old boy who had a history of polymerase chain reaction-confirmed COVID-19 and developed MIS-C approximately three weeks after an initial diagnosis of COVID-19. High fever with abdominal pain mimicking appendicitis was the initial manifestation of MIS-C, which could have been easily missed if the patient's history of C...
Source: J Korean Med Sci - January 11, 2021 Category: General Medicine Authors: Lee JH, Han HS, Lee JK Tags: J Korean Med Sci Source Type: research

Erratum: Correction of Text in the Article "Evidence of Long-Distance Droplet Transmission of SARS-CoV-2 by Direct Air Flow in a Restaurant in Korea".
Erratum: Correction of Text in the Article "Evidence of Long-Distance Droplet Transmission of SARS-CoV-2 by Direct Air Flow in a Restaurant in Korea". J Korean Med Sci. 2021 Jan 11;36(2):e23 Authors: Kwon KS, Park JI, Park YJ, Jung DM, Ryu KW, Lee JH Abstract This corrects the article on p. e415 in vol. 35, PMID: 33258335. PMID: 33429477 [PubMed - as supplied by publisher] (Source: J Korean Med Sci)
Source: J Korean Med Sci - January 11, 2021 Category: General Medicine Authors: Kwon KS, Park JI, Park YJ, Jung DM, Ryu KW, Lee JH Tags: J Korean Med Sci Source Type: research

Sarcopenia as a Predictor of Prognosis in Early Stage Ovarian Cancer.
Abstract BACKGROUND: To identify sarcopenia as a predictive prognostic factor of ovarian cancer in terms of survival outcome in patients with early-stage ovarian cancer. METHODS: Data of Konkuk University Medical Center from March 2002 to December 2017 were reviewed retrospectively. Eighty-two patients who underwent surgery due to early-stage (International Federation of Gynecology and Obstetrics stage I/II) ovarian cancer and had computed tomography (CT) images taken at the initial diagnosis were included. The initial CT scan images were analyzed with SliceOmatic software (TomoVision). A sarcopenia cutoff va...
Source: J Korean Med Sci - January 4, 2021 Category: General Medicine Authors: Chae SH, Lee C, Yoon SH, Shim SH, Lee SJ, Kim SN, Chung S, Lee JY Tags: J Korean Med Sci Source Type: research

Microbiological Features and Clinical Factors Associated with Empirical Antibiotic Resistance in Febrile Patients with Upper Urinary Tract Calculi.
CONCLUSION: Based on the present study results, quinolone was not recommended as the empirical treatment in febrile patients with upper urinary tract calculi. Combination antibiotic therapy is recommended in cases of recurrent infections due to the possible occurrence of cefotaxime resistance. PMID: 33398940 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - January 4, 2021 Category: General Medicine Authors: Cho S, Park MG, Lee KC, Cho SY, Lee JW Tags: J Korean Med Sci Source Type: research

Comparative Analysis of the Patients with Spontaneous Thalamic Hemorrhage with Concurrent Intraventricular Hemorrhage and Those without Intraventricular Hemorrhage.
CONCLUSION: Concurrent IVH is strongly associated with mortality in patients with STH. Delayed NPH may develop more frequently in STH patients with IVH who were treated with EVD. PMID: 33398941 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - January 4, 2021 Category: General Medicine Authors: Nam TM, Jang JH, Kim SH, Kim KH, Kim YZ Tags: J Korean Med Sci Source Type: research

Epidemiology and Clinical Patterns of Ocular Trauma at a Level 1 Trauma Center in Korea.
Abstract BACKGROUND: To evaluate the patterns of distribution and clinical manifestations of ocular injuries referred to the level 1 trauma center of Pusan National University Hospital (PNUH) in Korea. METHODS: We analyzed 254 of 4,287 patients who were referred to the Department of Ophthalmology at the level 1 trauma center of the PNUH, from January 2016 through December 2018. Data on the incidence of ocular injuries, sex, age, monthly and seasonal distribution, day and time of injury, side of injury, cause, residence of patients, referral time to an ophthalmologist and subsequent examination time, final vis...
Source: J Korean Med Sci - January 4, 2021 Category: General Medicine Authors: Park J, Yang SC, Choi HY Tags: J Korean Med Sci Source Type: research

COVID-19 Changes Medical Learning.
PMID: 33398943 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - January 4, 2021 Category: General Medicine Authors: Chung MS Tags: J Korean Med Sci Source Type: research

Etiological Distribution and Morphological Patterns of Granulomatous Pleurisy in a Tuberculosis-prevalent Country.
Abstract The cause of epithelioid granulomatous inflammation varies widely depending on the affected organ, geographic region, and whether the granulomas morphologically contain necrosis. Compared with other organs, the etiological distribution and morphological patterns of pleural epithelioid granulomas have rarely been investigated. We evaluated the final etiologies and morphological patterns of pleural epithelioid granulomatous inflammation in a tuberculosis (TB)-prevalent country. Of 83 patients with pleural granulomas, 50 (60.2%) had confirmed TB pleurisy (TB-P) and 29 (34.9%) had probable TB-P. Four patients...
Source: J Korean Med Sci - January 4, 2021 Category: General Medicine Authors: Lee J, Park S, Park JE, Choi SH, Seo H, Yoo SS, Lee SY, Kim YK, Cha SI, Park JY, Park TI, Kim CH Tags: J Korean Med Sci Source Type: research

Pediatric Emergency Department Utilization and Coronavirus Disease in Daegu, Korea.
CONCLUSION: The COVID-19 pandemic has led to a substantial decrease in pediatric ED utilization. These findings can help reallocate human and material resources in the EDs during infectious disease outbreaks. PMID: 33398945 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - January 4, 2021 Category: General Medicine Authors: Jang KM, Ahn JY, Choi HJ, Lee S, Kim D, Lee DW, Choe JY Tags: J Korean Med Sci Source Type: research

Clinical Characteristics and Outcomes of COVID-19 Cohort Patients in Daegu Metropolitan City Outbreak in 2020.
CONCLUSION: Overall, asymptomatic to mild patients were approximately 77% of the total cohort (asymptomatic, 30.6%). The case fatality rate was 2.5%. Risk factors, including older age, need for O₂ supply, dementia, and neurological disorder at admission, could help clinicians to identify COVID-19 patients with poor prognosis at an early stage. PMID: 33398946 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - January 4, 2021 Category: General Medicine Authors: Kim SW, Kim SM, Kim YK, Kim JY, Lee YM, Kim BO, Hwangbo S, Park T Tags: J Korean Med Sci Source Type: research

Adaptations in Anatomy Education during COVID-19.
CONCLUSION: This study suggests that a blended learning approach is an effective method for anatomy learning, and the advantage may result from increased self-directed study through online learning. PMID: 33398947 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - January 4, 2021 Category: General Medicine Authors: Yoo H, Kim D, Lee YM, Rhyu IJ Tags: J Korean Med Sci Source Type: research

Systematic Preventable Trauma Death Rate Survey to Establish the Region-based Inclusive Trauma System in a Representative Province of Korea.
CONCLUSION: The preventable trauma death rate was slightly lower in this study than in previous studies, although several problems were noted during inter-hospital transfer; in the hospital stage, more problems were noted at emergency medical care facilities than at regional trauma centers. Further, several opportunities for improvements were discovered regarding bleeding control. PMID: 33372420 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 28, 2020 Category: General Medicine Authors: Kwon J, Lee JH, Hwang K, Heo Y, Cho HJ, Lee JCJ, Jung K Tags: J Korean Med Sci Source Type: research

Establishing a Patient-centered Longitudinal Integrated Clerkship: Early Results from a Single Institution.
Discussion classes on set topics were held seven times per year with facilitators and clinical faculites. Students completed a course evaluation questionnaire at the end of the academic year. The questionnaire included 22 items measured on a 5-point scale and two open-ended questions asking about the benefits and limitations of the program. The items covered three domains: student experience, satisfaction, and self-assessment. Final reflective essays were collected as both student assessments and data for qualitative analysis. RESULTS: During the study period, the overall experience of the students improved. We increa...
Source: J Korean Med Sci - December 28, 2020 Category: General Medicine Authors: Kim JW, Ryu H, Park JB, Moon SH, Myung SJ, Park WB, Yim JJ, Yoon HB Tags: J Korean Med Sci Source Type: research

Expression of Estrogen Receptor-alpha in Nasal Polyps and the Effects of Dexamethasone on Estrogen Receptor-alpha Expression in RPMI 2650 Cells.
CONCLUSION: ER-α expression was higher in NPs than in healthy inferior turbinate mucosae. When RPMI 2650 cells were treated with dexamethasone, ER-α expression was downregulated, cell viability decreased, and apoptosis increased. The decreased cell viability may be related, at least in part, to the decreased ER-α protein levels, which likely contributed to the induction of apoptotic cell death in RPMI 2650 cells. PMID: 33372422 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 28, 2020 Category: General Medicine Authors: Ban WW, Lee YJ, Lee SH, Jung JY, Baek BJ Tags: J Korean Med Sci Source Type: research

Exposure to Adverse Childhood Experiences (ACEs) and Stress among the Community-based Urban Pediatric Population in Korea.
CONCLUSION: This is the first study of self-reported ACEs from a community-based pediatric population in Korea. We found that the number of the students revealed more than one ACEs was similar to the data in the US community study with self-reporting among the community samples and exposure to adverse experiences is highly correlated with various stress responses. PMID: 33372423 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 28, 2020 Category: General Medicine Authors: Lee MS, Kim HS, Bhang SY Tags: J Korean Med Sci Source Type: research

Cannabidiol for Treating Lennox-Gastaut Syndrome and Dravet Syndrome in Korea.
CONCLUSION: In this first Korean study, CBD was safe and tolerable for use and could be expected to potentially reduce the seizure frequency in pediatric patients with LGS or DS. PMID: 33372424 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 28, 2020 Category: General Medicine Authors: Koo CM, Kim SH, Lee JS, Park BJ, Lee HK, Kim HD, Kang HC Tags: J Korean Med Sci Source Type: research

Risk of COVID-19 Transmission from Infected Outpatients to Healthcare Workers in an Outpatient Clinic.
Abstract From January to September 2020, we conducted contact-tracing for confirmed coronavirus disease 2019 (COVID-19) patients who visited our outpatient clinic to evaluate the risk of COVID-19 transmission from infected patients to healthcare workers (HCWs). COVID-19 was diagnosed in 8 outpatients. Per the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) polymerase chain reaction test results, none of the 317 HCWs who came in contact had a confirmed COVID-19 diagnosis (0.00%; 95% confidence interval, 0.00%-0.01%). This low rate of transmission from infected outpatients to HCWs suggests that standard...
Source: J Korean Med Sci - December 28, 2020 Category: General Medicine Authors: Chung H, Kim EO, Kim SH, Jung J Tags: J Korean Med Sci Source Type: research

Association between Chronic Kidney Disease or Acute Kidney Injury and Clinical Outcomes in COVID-19 Patients.
Abstract BACKGROUND: A population-based study would be useful to identify the association between chronic kidney disease (CKD) or acute kidney injury (AKI) and prognosis of coronavirus disease 2019 (COVID-19) patients. METHODS: This retrospective study utilized the claim data from Korea. Patients who underwent COVID-19 testing and were confirmed to be positive were included and divided into the following three groups based on the presence of CKD or requirement of maintenance dialysis: Non-CKD (participants without CKD), non-dialysis CKD (ND-CKD), and dialysis-dependent CKD (DD-CKD) patients. We collected data...
Source: J Korean Med Sci - December 28, 2020 Category: General Medicine Authors: Kang SH, Kim SW, Kim AY, Cho KH, Park JW, Do JY Tags: J Korean Med Sci Source Type: research

The Serial Interval of COVID-19 in Korea: 1,567 Pairs of Symptomatic Cases from Contact Tracing.
Abstract Although coronavirus disease 2019 (COVID-19) is an ongoing pandemic, the mean serial interval was measured differently across nations. Through the Korean national COVID-19 contact tracing system, we were able to investigate personal contacts in all symptomatic cases in Korea from January 20 to August 3, 2020. The mean serial interval was calculated by the duration between the symptom onset of the infector and infectee, and became shorter after the case definition changed to include not-imported cases in Korea on February 20, 2020. The mean serial interval before and after this fifth case definition was 6....
Source: J Korean Med Sci - December 28, 2020 Category: General Medicine Authors: Hong K, Yum S, Kim J, Chun BC Tags: J Korean Med Sci Source Type: research

Trend of Menarcheal Age among Korean Girls.
Abstract BACKGROUND: Menarcheal age has been decreasing worldwide. However, few recent studies have observed trends in menarcheal age in larger populations, and the cutoff age for early menarche remains unclear. Therefore, we aimed to analyze recent trends of menarcheal age and to determine the cutoff age of early menarche based on nationally representative data. METHODS: We conducted a cross-sectional study of 351,006 Korean girls aged 12-18 years who were born in 1988-2003 based on the data of the 2006-2015 Korea Youth Risk Behavior Survey. We identified the distribution of age at menarche using the complex...
Source: J Korean Med Sci - December 21, 2020 Category: General Medicine Authors: Seo MY, Kim SH, Juul A, Park MJ Tags: J Korean Med Sci Source Type: research

Current and Future Burden of Periprosthetic Joint Infection from National Claim Database.
CONCLUSION: The incidence of PJI in Korea is comparable with reported PJI incidence of 2.0%-2.7% in the United States. Our findings would be used for worldwide comparison of PJI epidemiology and establishment of healthcare policies for PJI in East Asia. PMID: 33350183 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 21, 2020 Category: General Medicine Authors: Kim HS, Park JW, Moon SY, Lee YK, Ha YC, Koo KH Tags: J Korean Med Sci Source Type: research

The Effects of Single Nucleotide Polymorphisms in Korean Patients with Early-onset Atrial Fibrillation after Catheter Ablation.
This study evaluated the status of single nucleotide polymorphisms (SNPs) in Korean patients with early-onset (
Source: J Korean Med Sci - December 21, 2020 Category: General Medicine Authors: Park YM, Roh SY, Lee DI, Shim J, Choi JI, Park SW, Kim YH Tags: J Korean Med Sci Source Type: research

Circulating Respiratory Syncytial Virus Genotypes and Genetic Variability of the G Gene during 2017 and 2018/2019 Seasonal Epidemics Isolated from Children with Lower Respiratory Tract Infections in Daejeon, Korea.
CONCLUSION: RSV-B belonging to BA9 in 2017, and RSV-A belonging to ON1 genotype in 2018/2019 was the most prevalent circulating genotypes during the two RSV seasons in Daejeon, Korea. PMID: 33350185 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 21, 2020 Category: General Medicine Authors: Kang HM, Park KC, Park J, Kil HR, Yang EA Tags: J Korean Med Sci Source Type: research

Infectious Diseases Physician Workforce in Korea.
This study aimed to evaluate the infectious disease (ID) physician workforce in Korea. We investigated the acquisition of ID physicians from 1992 to 2019 with their current working place in the Health Care System. We defined ID physicians working at general or tertiary-care hospitals as active ID physicians. A total 275 physicians acquired ID as a sub-specialty. Among the 275, 242 were active ID physicians. The density of active ID physicians was 0.47 per 100,000 population. Of all the 17 administrative districts, 11 (64.7%) fell short of 0.47, and 131 medical institutions employed the service of ID physicians. The median ...
Source: J Korean Med Sci - December 21, 2020 Category: General Medicine Authors: Jang Y, Park SY, Kim B, Lee E, Lee S, Son HJ, Park JW, Yu SN, Kim T, Jeon MH, Choo EJ, Kim TH Tags: J Korean Med Sci Source Type: research

Quarantine Facility for Patients with COVID-19 with Mild Symptoms in Korea: Experience from Eighteen Residential Treatment Centers.
Abstract With the rapid spread of coronavirus disease 2019 (COVID-19), a particularly sharp increase in the number of confirmed cases in Daegu and Gyeongbuk regions at the end of February, Korea faced an unprecedented shortage of medical resources, including hospital beds. To cope with this shortage, the government introduced a severity scoring system for patients with COVID-19 and designed a new type of quarantine facility for treating and isolating patients with mild symptoms out of the hospital, namely, the Residential Treatment Center (RTC). A patient with mild symptoms was immediately isolated in the RTC and ...
Source: J Korean Med Sci - December 21, 2020 Category: General Medicine Authors: Yang Y, Kim H, Hwang J Tags: J Korean Med Sci Source Type: research

Respiratory Specimen Collection Booth for COVID-19 Test: Efficiency Based Newly Introduced Facility.
Abstract Hospitals need to find a safe and rapid method for respiratory specimen collection as the number of patients suspicious for coronavirus disease -2019 (COVID-19) rapidly grows. Applied with significant infection control and prevention measures, a respiratory specimen collection booth was newly designed. The new respiratory specimen collection booth not only increased COVID-19 testing cases but also decreased personal protective equipment consumption. PMID: 33350188 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 21, 2020 Category: General Medicine Authors: Kim Y, Yu I, Kweon O, Choi JY, Yong D, Park ES Tags: J Korean Med Sci Source Type: research

A Debate on Public Health Responses to COVID-19: Focused Protection versus Sustained Suppression.
Abstract With the coronavirus disease 2019 (COVID-19) pandemic persisting for a long time, there have been debates about the public health response strategies. We conducted a survey of adult infectious disease specialists on public health responses to COVID-19. Most responded that regulations on multi-use facilities should be maintained or strengthened, but schools should not be closed, except in cases where an outbreak occurs within the school. A slightly higher percentage of experts supported focused protection rather than sustained suppression. While the focused protection strategy might suffice in low-level ep...
Source: J Korean Med Sci - December 21, 2020 Category: General Medicine Authors: Song JY, Peck KR, Korean Society of Infectious Diseases Tags: J Korean Med Sci Source Type: research

Clinical Outcomes of Early Extubation Strategy in Patients Undergoing Extracorporeal Membrane Oxygenation as a Bridge to Heart Transplantation.
Abstract BACKGROUND: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) might be considered a bridge therapy in patients who are expected to have short waiting times for heart transplantation. We investigated the clinical outcomes of patients who underwent VA-ECMO as a bridge to heart transplantation and whether the deployment of an early extubation ECMO strategy is beneficial. METHODS: Between November 2006 and December 2018, we studied 102 patients who received VA-ECMO as a bridge to heart transplantation. We classified these patients into an early extubation ECMO group (n = 24) and a deferred extu...
Source: J Korean Med Sci - November 2, 2020 Category: General Medicine Authors: Youn T, Kim D, Park TK, Cho YH, Cho SH, Choi JY, Sung K, Choi JO, Jeon ES, Yang JH Tags: J Korean Med Sci Source Type: research

Incremental Predictive Value of Plasma Renin Activity as a Prognostic Biomarker in Patients with Heart Failure.
This study aimed to determine the association between NT-proBNP and PRA and to investigate the incremental value of PRA to NT-proBNP for predicting long term prognosis in patients with acute HF. METHODS: Three hundred and ninety-six patients (mean age, 64.7 ± 15.9 years; 46.5% female) presenting with acute HF were enrolled between December 2004 and July 2013. Patients with newly diagnosed HF as well as patients with acute exacerbated chronic HF were included. The prognosis was assessed with the composite event of all-cause mortality and readmission for HF during a 2-year follow-up period. RESULTS: The etio...
Source: J Korean Med Sci - November 2, 2020 Category: General Medicine Authors: Park BE, Yang DH, Kim HJ, Park YJ, Kim HN, Jang SY, Bae MH, Lee JH, Park HS, Cho Y, Chae SC Tags: J Korean Med Sci Source Type: research

Development of a Transitional Care Model Program for Patients with Pneumonia, Asthma, and Chronic Obstructive Pulmonary Disease: In-depth Interviews with Readmitted Patients.
Abstract Community-based health management policies are needed considering societal aging. We aimed to develop a transitional care model (TCM) program for patients with pneumonia, asthma, and chronic obstructive pulmonary disease. First, we conducted in-depth interviews with patients who were hospitalized, released, and readmitted for those three conditions to identify issues with the current hospitalization/discharge system and post-discharge processes. Next, we developed a new TCM program suited to the realities of the current medical environment. Interviews revealed problems including inadequate awareness of di...
Source: J Korean Med Sci - November 2, 2020 Category: General Medicine Authors: Jo HS, Jeong S, Kim WJ, Park S, Yu SA Tags: J Korean Med Sci Source Type: research

Prevalence and Risk Factors of Gastric and Colorectal Cancer after Cholecystectomy.
CONCLUSION: Cholecystectomy may increase risk of CRC, especially in females. Age was considered a risk factor of GI cancers in patients with history of cholecystectomy. PMID: 33140590 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - November 2, 2020 Category: General Medicine Authors: Kim SB, Kim KO, Kim TN Tags: J Korean Med Sci Source Type: research

Artificial Intelligence in Health Care: Current Applications and Issues.
Abstract In recent years, artificial intelligence (AI) technologies have greatly advanced and become a reality in many areas of our daily lives. In the health care field, numerous efforts are being made to implement the AI technology for practical medical treatments. With the rapid developments in machine learning algorithms and improvements in hardware performances, the AI technology is expected to play an important role in effectively analyzing and utilizing extensive amounts of health and medical data. However, the AI technology has various unique characteristics that are different from the existing health care...
Source: J Korean Med Sci - November 2, 2020 Category: General Medicine Authors: Park CW, Seo SW, Kang N, Ko B, Choi BW, Park CM, Chang DK, Kim H, Kim H, Lee H, Jang J, Ye JC, Jeon JH, Seo JB, Kim KJ, Jung KH, Kim N, Paek S, Shin SY, Yoo S, Choi YS, Kim Y, Yoon HJ Tags: J Korean Med Sci Source Type: research

Universal Screening of Severe Acute Respiratory Syndrome Coronavirus 2 with Polymerase Chain Reaction Testing after Rally of Trainee Doctors.
Abstract There were two rallies of medical students and trainee doctors, where 9,000 participants gathered. We performed polymerase chain reaction (PCR)-based universal screening for the participants using pooling at a tertiary care hospital. Around 609 (94%) of 646 participants underwent PCR tests for severe acute respiratory syndrome coronavirus 2; all of them tested negative. Our data suggested low transmission rates in open air mass gatherings when appropriate personal protective practices were followed. PMID: 33140592 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - November 2, 2020 Category: General Medicine Authors: Kim SK, Kim EO, Kim SH, Jung J Tags: J Korean Med Sci Source Type: research

Coping with Dementia in the Middle of the COVID-19 Pandemic.
Abstract Multiple neurological complications have been associated with the coronavirus disease-19 (COVID-19), which is caused by severe acute respiratory syndrome coronavirus 2. This is a narrative review to gather information on all aspects of COVID-19 in elderly patients with cognitive impairment. First, the following three mechanisms have been proposed to underlie the neurological complications associated with COVID-19: 1) direct invasion, 2) immune and inflammatory reaction, and 3) hypoxic brain damage by COVID-19. Next, because the elderly dementia patient population is particularly vulnerable to COVID-19, we...
Source: J Korean Med Sci - November 2, 2020 Category: General Medicine Authors: Ryoo N, Pyun JM, Baek MJ, Suh J, Kang MJ, Wang MJ, Youn YC, Yang DW, Kim SY, Park YH, Kim S Tags: J Korean Med Sci Source Type: research

Delay or Giving Up of Influenza Vaccination Induced by Unscientific Journalism Makes Influenza Outbreak and Its Subsequent Cardiovascular Death Surges Especially in Elderly.
PMID: 33140594 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - November 2, 2020 Category: General Medicine Authors: Bae JW Tags: J Korean Med Sci Source Type: research

Erratum: Correction of Text and Table 1 in the Article "National Trends in the Treatment of Ruptured Cerebral Aneurysms in Korea Using an Age-adjusted Method".
Erratum: Correction of Text and Table 1 in the Article "National Trends in the Treatment of Ruptured Cerebral Aneurysms in Korea Using an Age-adjusted Method". J Korean Med Sci. 2020 Nov 02;35(42):e384 Authors: Park HR, Kim JH, Park S, Chang JC, Park SQ Abstract This corrects the article on p. e323 in vol. 35, PMID: 33045768. PMID: 33140595 [PubMed] (Source: J Korean Med Sci)
Source: J Korean Med Sci - November 2, 2020 Category: General Medicine Authors: Park HR, Kim JH, Park S, Chang JC, Park SQ Tags: J Korean Med Sci Source Type: research

Novel Endoscopic Criteria for Predicting Tumor Invasion Depth in Superficial Esophageal Squamous Carcinoma.
Abstract BACKGROUND: Accurate prediction of tumor invasion depth in superficial esophageal squamous carcinoma (SESC) is essential for deciding the appropriate treatment strategy. We proposed novel endoscopic criteria to differentiate between mucosal and submucosal esophageal cancers and to evaluate the diagnostic accuracy and usefulness of the criteria. METHODS: A total of 352 patients who underwent endoscopic or surgical resection for SESC between 1991 and 2010 were included. First, the novel endoscopic criteria were created based on the endoscopic features of 60 randomly selected patients as follows: for T1...
Source: J Korean Med Sci - October 26, 2020 Category: General Medicine Authors: Choi JY, Bae SE, Ahn JY, Lee JH, Park YS, Kim DH, Choi KD, Chang HS, Song HJ, Lee GH, Choe J, Jang SJ, Jung HY Tags: J Korean Med Sci Source Type: research

Strategy for Prostate Cancer Patients with Low Prostate Specific Antigen Level (2.5 to 4.0 ng/mL).
Abstract BACKGROUND: To evaluate the strategy for detection of prostate cancer (PCa) with low prostate specific antigen (PSA) level (2.5-4.0 ng/mL), prostate biopsy patients with low PSA were assessed. We evaluated the risk of low PSA PCa and the strategy for screening low-PSA patients. METHODS: We retrospectively analyzed the patients who underwent prostate biopsy with low PSA level. Baseline characteristics, PSA level before prostate biopsy, prostate volume, prostate specific antigen density (PSAD), and pathological data were assessed. RESULTS: Among the 1986 patients, 24.97% were diagnosed with PCa. T...
Source: J Korean Med Sci - October 26, 2020 Category: General Medicine Authors: Chung JH, Yu J, Song W, Kang M, Sung HH, Jeon HG, Jeong BC, Seo SI, Lee HM, Jeon SS Tags: J Korean Med Sci Source Type: research

Routing to Endovascular Treatment of Ischemic Stroke in Korea: Recognition of Need for Process Improvement.
Abstract BACKGROUND: To track triage, routing, and treatment status regarding access to endovascular treatment (EVT) after acute ischemic stroke (AIS) at a national level. METHODS: From national stroke audit data, potential candidates for EVT arriving within 6 hours with National Institute of Health Stroke Scale score of ≥ 7 were identified. Acute care hospitals were classified as thrombectomy-capable hospitals (TCHs, ≥ 15 EVT cases/year) or primary stroke hospital (PSH,
Source: J Korean Med Sci - October 26, 2020 Category: General Medicine Authors: Kang J, Kim SE, Park HK, Cho YJ, Kim JY, Lee KJ, Park JM, Park KY, Lee KB, Lee SJ, Lee JS, Lee J, Yang KH, Choi AR, Kang MY, Choi NC, Gorelick PB, Bae HJ Tags: J Korean Med Sci Source Type: research

Trends of Cause of Death among Human Immunodeficiency Virus Patients and the Impact of Low CD4 Counts on Diagnosis to Death: a Retrospective Cohort Study.
Abstract BACKGROUND: Monitoring the full spectrum of causes of death among human immunodeficiency virus (HIV) patients has become increasingly important as survival improves because of highly active antiretroviral therapy. However, there are no recently published data regarding the changes in the causes of death among HIV patients based on year of HIV diagnosis, and the impact of low CD4 count at the time of HIV diagnosis on the clinical outcome is still unclear in Korea. METHODS: A retrospective cohort study was conducted with 801 patients with HIV infection who were followed up at a tertiary university hosp...
Source: J Korean Med Sci - October 26, 2020 Category: General Medicine Authors: Kim Y, Kim SW, Chang HH, Kwon KT, Bae S, Hwang S Tags: J Korean Med Sci Source Type: research

COVID-19 Outbreak and Its Association with Healthcare Workers' Emotional Stress: a Cross-Sectional Study.
CONCLUSION: The COVID-19 outbreak is correlated with healthcare workers' emotional stress, and specific types of jobs and duties involving close contact with these patients can be risk factors. Interestingly, even low-exposure groups reported significant depression and anxiety as a result of social stigma and uncertainty. Adequate and timely management measures for emotional stress are required for vulnerable and at-risk groups. PMID: 33107230 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - October 26, 2020 Category: General Medicine Authors: Park C, Hwang JM, Jo S, Bae SJ, Sakong J Tags: J Korean Med Sci Source Type: research

Bladder Regeneration Using a Polycaprolactone Scaffold with a Gradient Structure and Growth Factors in a Partially Cystectomized Rat Model.
CONCLUSION: This study showed that a PCL scaffold with a gradient structure incorporating GFs improved bladder regeneration functionally and histologically. PMID: 33107231 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - October 26, 2020 Category: General Medicine Authors: Kim HY, Chun SY, Lee EH, Kim B, Ha YS, Chung JW, Lee JN, Kim BS, Oh SH, Kwon TG Tags: J Korean Med Sci Source Type: research

Trend of Olfactory and Gustatory Dysfunction in COVID-19 Patients in a Quarantine Facility.
CONCLUSIONS: The prevalence of olfactory and gustatory dysfunction was 24.2% in mild COVID-19 patients. All patients had hyposmia due to sensorineural olfactory dysfunction, which was confirmed using validated olfactory and gustatory evaluation methods and endoscopic examination. Olfactory and gustatory dysfunction may be characteristic indicators of mild COVID-19. PMID: 33107232 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - October 26, 2020 Category: General Medicine Authors: Seo MY, Seok H, Hwang SJ, Choi HK, Jeon JH, Sohn JW, Park DW, Lee SH, Choi WS Tags: J Korean Med Sci Source Type: research