Erratum: Addition of a Co-Author: Etiology of Invasive Bacterial Infections in Immunocompetent Children in Korea (2006-2010): a Retrospective Multicenter Study.
Abstract This corrects the article on e45 in vol. 33, PMID: 29349940. PMID: 31243938 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - June 28, 2019 Category: General Medicine Authors: Rhie K, Choi EH, Cho EY, Lee J, Kang JH, Kim DS, Kim YJ, Ahn Y, Eun BW, Oh SH, Cha SH, Hong YJ, Kim KN, Kim NH, Kim YK, Kim JH, Lee T, Kim HM, Lee KS, Kim CS, Park SE, Kim YM, Oh CE, Ma SH, Jo DS, Choi YY, Lee HJ Tags: J Korean Med Sci Source Type: research

Acute Necrotizing Encephalopathy in Children: a Long Way to Go.
CONCLUSION: ANE is a distinctive type of acute encephalopathy with diverse clinical spectrum. Even though the diagnostic criteria are available, they might not be watertight. In addition, treatment options are still limited. Further studies for better outcome are needed. PMID: 31099193 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 18, 2019 Category: General Medicine Authors: Lee YJ, Hwang SK, Kwon S Tags: J Korean Med Sci Source Type: research

Methylation Signature for Prediction of Progression Free Survival in Surgically Treated Clear Cell Renal Cell Carcinoma.
CONCLUSION: The promoter methylation of ZNF278, FAM155A and DPP6 genes are associated with aggressive tumor phenotype and early development of distant metastasis in patients with surgically treated ccRCC. These potential methylation markers, either alone, or in combination, could provide novel targets for development of individualized therapeutic and prevention regimens. PMID: 31099194 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 18, 2019 Category: General Medicine Authors: Kang HW, Park H, Seo SP, Byun YJ, Piao XM, Kim SM, Kim WT, Yun SJ, Jang W, Shon HS, Ryu KH, Lee SC, Kim WJ, Kim YJ Tags: J Korean Med Sci Source Type: research

Influence of Local Myocardial Infarction on Endothelial Function, Neointimal Progression, and Inflammation in Target and Non-Target Vascular Territories in a Porcine Model of Acute Myocardial Infarction.
CONCLUSION: In the pig model, AMI events induced endothelial dysfunction, inflammation, and neointimal progression in the target and non-target vessels. PMID: 31099195 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 18, 2019 Category: General Medicine Authors: Kim HK, Kim HB, Lee JM, Kim SS, Bae IH, Park DS, Park JK, Shim JW, Na JY, Lee MY, Kim JS, Sim DS, Hong YJ, Nam CW, Doh JH, Park J, Koo BK, Kim SU, Lim KS, Jeong MH Tags: J Korean Med Sci Source Type: research

Social Consensus is Required for Legal Induced Abortion.
PMID: 31099196 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 18, 2019 Category: General Medicine Authors: Hwang JY Tags: J Korean Med Sci Source Type: research

In Favor of Discussion on the Amendment of the "Abortion Prohibition Law" in Korea.
Discussion on the Amendment of the "Abortion Prohibition Law" in Korea. J Korean Med Sci. 2019 May 20;34(19):e148 Authors: Lee M PMID: 31099197 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 18, 2019 Category: General Medicine Authors: Lee M Tags: J Korean Med Sci Source Type: research

Retraction: Factors Influencing the Diagnosis and Treatment of Latent Tuberculosis among Contacts in Congregated Settings in Korea.
Authors: Abstract This retracts the article e138 in vol. 34, PMID: 31074252. PMID: 31099198 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 18, 2019 Category: General Medicine Tags: J Korean Med Sci Source Type: research

Induced Abortion Law Respecting Doctor's Judement.
PMID: 31099199 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 18, 2019 Category: General Medicine Authors: Chung MS Tags: J Korean Med Sci Source Type: research

Prognostic Effect of Guideline-Directed Therapy Is More Noticeable Early in the Course of Heart Failure.
CONCLUSION: The prognostic implications of adherence to guideline-directed therapy at discharge were more pronounced in de novo heart failure. We recommend that guideline-directed therapy be started as early as possible in the course of heart failure with reduced ejection fraction. PMID: 31050223 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 4, 2019 Category: General Medicine Authors: Ahn MS, Yoo BS, Yoon J, Lee SH, Kim JY, Ahn SG, Youn YJ, Lee JW, Son JW, Kim HS, Kang DR, Lee SE, Cho HJ, Lee HY, Jeon ES, Kang SM, Choi DJ, Cho MC Tags: J Korean Med Sci Source Type: research

New Termination-of-Resuscitation Models and Prognostication in Out-of-Hospital Cardiac Arrest Using Electrocardiogram Rhythms Documented in the Field and the Emergency Department.
CONCLUSION: Survival outcomes and TOR predictions varied depending on ECG rhythm types and documentation times within pre-hospital filed or emergency department and should, in the future, be considered in treatment algorithms and prognostications of patients with out-of-hospital cardiac arrest. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT03222999. PMID: 31050224 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 4, 2019 Category: General Medicine Authors: Lee DE, Lee MJ, Ahn JY, Ryoo HW, Park J, Kim WY, Shin SD, Hwang SO, Korean Cardiac Arrest Research Consortium (KoCARC) Tags: J Korean Med Sci Source Type: research

Appropriate Prophylactic Antibiotic Use in Clean Wound Surgery Under Local Anesthesia.
CONCLUSION: Intravenous injection of single-dose first-generation cephalosporins 1 hour before surgery without postoperative antibiotics did not increase the incidence of SSIs compared with the usual practice of giving only postoperative antibiotics prescription for 2 to 3 days in cases of clean wound surgery performed under local anesthesia. Proper antibiotic prophylaxis should be performed by surgeons in training hospitals without hesitation. PMID: 31050225 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 4, 2019 Category: General Medicine Authors: Cha HG, Kwon JG, Han HH, Eom JS, Kim EK Tags: J Korean Med Sci Source Type: research

Appropriate Use of Surgical Antibiotic Prophylaxis.
PMID: 31050226 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 4, 2019 Category: General Medicine Authors: Kwak YG Tags: J Korean Med Sci Source Type: research

Medical Concerns of Induced Abortion and Contraception.
PMID: 31050227 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - May 4, 2019 Category: General Medicine Authors: Kim YS Tags: J Korean Med Sci Source Type: research

Drawing Guideline for JKMS Manuscript (01) Kaplan-Meier Curve and Survival Analysis.
Abstract The appropriate plot effectively conveys the author's conclusions to readers. Journal of Korean Medical Science will provide a series of special articles to show you how to make consistent and excellent plots easier. In the first of this series of special articles, I will cover Kaplan-Meier curve (or Kaplan-Meier plot) and the ease tools. This plot, generated as a result of the Survival Analysis, provides a visualization of the 'Kaplan-Meier Survival Probability Estimate' for each group. PMID: 30833878 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - March 4, 2019 Category: General Medicine Authors: Kim J Tags: J Korean Med Sci Source Type: research

Incidence and Prevalence of Idiopathic Inflammatory Myopathies in Korea: a Nationwide Population-based Study.
Conclusion: In Korea, the incidence and prevalence of IIM were 2.9-5.2/1,000,000 PY and 2.3-4.0/100,000 PY, respectively. PMID: 30833879 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - March 4, 2019 Category: General Medicine Authors: Cho SK, Kim H, Myung J, Nam E, Jung SY, Jang EJ, Yoo DH, Sung YK Tags: J Korean Med Sci Source Type: research

Heart Rate Change While Drowsy Driving.
Abstract Heart rate (HR) change during sleepy driving has never been investigated. Healthy volunteers who planned to drive a long distance were recruited and monitored with a 24-hour Holter. Six healthy volunteers were enrolled. Their mean driving time was 297.7 ± 111 minutes. Mean duration of sleepy time while driving was 27 ± 24.5 minutes. Driving HR showed a trend for increment as compared to day time mean HR, from 85 ± 5.6 to 89.8 ± 5.6 beats/min (by 7%) (P = 0.093). Mean HR while sleepy driving significantly decreased to 81.5 ± 9.2 beats/min by 9.3% ± 7.4% (P = 0.046)...
Source: J Korean Med Sci - March 4, 2019 Category: General Medicine Authors: Jo SH, Kim JM, Kim DK Tags: J Korean Med Sci Source Type: research

Frameless Fractionated Gamma Knife Radiosurgery with ICON ™ for Large Metastatic Brain Tumors.
Conclusion: Daily FF GKRS by gamma knife ICON™ revealed satisfactory tumor control rate and low morbidity, despite the short follow-up period. Further prospective studies and a longer follow-up of a large cohort of patients diagnosed with brain metastases are required to elucidate the effect of FF GKRS in brain metastases. PMID: 30833881 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - March 4, 2019 Category: General Medicine Authors: Park HR, Park KW, Lee JM, Kim JH, Jeong SS, Kim JW, Chung HT, Kim DG, Paek SH Tags: J Korean Med Sci Source Type: research

Preventable Trauma Death Rate after Establishing a National Trauma System in Korea.
Conclusion: Although the PTDR in Korea is still high compared to that in developed countries, it was lower when the time spent from the accident to the death was shorter and the final destined institution was the RTC. To reduce PTDR, it is necessary to make an effort to transfer trauma patients to RTCs directly within an appropriate time. PMID: 30833882 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - March 4, 2019 Category: General Medicine Authors: Jung K, Kim I, Park SK, Cho H, Park CY, Yun JH, Kim OH, Park JO, Lee KJ, Hong KJ, Yoon HD, Park JM, Kim S, Sung HK, Choi J, Kim Y Tags: J Korean Med Sci Source Type: research

Rise of the Visible Monkey: Sectioned Images of Rhesus Monkey.
Conclusion: Due to small intervals of these images, continuous structures could be traced completely. Moreover, 3D models of the skin and brain could be used for virtual dissections. Sectioned images of this study will enhance the understanding of monkey anatomy and foster further studies. These images will be provided to any requesting researcher free of charge. PMID: 30833883 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - March 4, 2019 Category: General Medicine Authors: Chung BS, Jeon CY, Huh JW, Jeong KJ, Har D, Kwack KS, Park JS Tags: J Korean Med Sci Source Type: research

Three-dimensional (3D) Models of Monkey and Human.
PMID: 30833884 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - March 4, 2019 Category: General Medicine Authors: Chung BS Tags: J Korean Med Sci Source Type: research

Impact of Day 14 Peripheral Blood Chimerism after Allogeneic Hematopoietic Stem Cell Bone Transplantation on the Treatment Outcome of Non-Malignant Disease.
Abstract Background: The impact of early peripheral blood chimerism on the outcome of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is unclear. We aimed to determine whether day 14 peripheral blood chimerism after allo-HSCT predicts outcomes in patients with non-malignant diseases. Methods: Data from 56 patients who received allo-HSCT between April 2007 and March 2016 were retrospectively analyzed. Chimerism was evaluated using short-tandem repeat polymerase chain reaction, with mixed chimerism (MC) defined as greater than 1% recipient cells which was further categorized into low-level MC (> 1% and
Source: J Korean Med Sci - February 18, 2019 Category: General Medicine Authors: Choi YB, Lee JW, Sung KW, Koo HH, Kim HJ, Yoo KH Tags: J Korean Med Sci Source Type: research

Effect of Phacoemulsification on Intraocular Pressure in Healthy Subjects and Glaucoma Patients.
Abstract Background: We investigated how cataract surgery might influence long-term intraocular pressure (IOP) change in both healthy subjects and glaucoma patients. Methods: A retrospective analysis of patients who had had clear corneal phacoemulsification with a minimum of 12 months of follow up was performed. Glaucoma patients with medically controlled open-angle glaucoma and healthy subjects with no glaucoma were included in the analysis. The change of IOP after phacoemulsification and factors associated with postoperative IOP change were investigated. Results: In total, 754 eyes of 754 patients, spe...
Source: J Korean Med Sci - February 18, 2019 Category: General Medicine Authors: Baek SU, Kwon S, Park IW, Suh W Tags: J Korean Med Sci Source Type: research

Metabolic Syndrome Severity Score in Korean Adults: Analysis of the 2010-2015 Korea National Health and Nutrition Examination Survey.
Abstract Background: Continuous metabolic syndrome (MS) severity scores that can track metabolic risk in individuals over time have been developed for Western populations. The present study aimed to develop gender- and age-specific equations for MS severity scores in Korean adults. Methods: Using data from the Korea National Health and Nutrition Examination Surveys (KNHANES) IV (2010-2012) and VI (2013-2015), we performed a confirmatory factor analysis of single MS factor that allowed for differential loadings across groups to generate gender- and age-specific, continuous MS severity scores. Then, we validate...
Source: J Korean Med Sci - February 18, 2019 Category: General Medicine Authors: Huh JH, Lee JH, Moon JS, Sung KC, Kim JY, Kang DR Tags: J Korean Med Sci Source Type: research

Incidence of Prostate Cancer according to Metabolic Health Status: a Nationwide Cohort Study.
Abstract Background: We assessed the association between metabolic health status and incidence of prostate cancer using the National Health Check-ups (NHC) database of Korea. Methods: A total of 11,771,252 men who participated in the NHC between 2009 and 2012 and 56,552 men who were newly diagnosed with prostate cancer were analyzed. Normal-weight and obesity were defined as body mass index (BMI)
Source: J Korean Med Sci - February 18, 2019 Category: General Medicine Authors: Kim JW, Ahn ST, Oh MM, Moon DG, Han K, Park HS Tags: J Korean Med Sci Source Type: research

Current Management of Cancer-associated Venous Thromboembolism: Focus on Direct Oral Anticoagulants.
Abstract Cancer-associated venous thromboembolism (CAT) is a common complication associated with high morbidity and mortality. In accordance with major clinical trials comparing low-molecular-weight heparin (LMWH) with a vitamin K antagonist (VKA), LMWH is currently the standard treatment for CAT, owing to its efficacy for thrombosis recurrence and improved safety profile compared to VKA. Over the past few years, direct oral anticoagulants (DOACs) have emerged as potential alternative therapies to LMWH due to their convenient route of administration and predictable pharmacokinetics, but evidence for their use in C...
Source: J Korean Med Sci - February 18, 2019 Category: General Medicine Authors: Kim SA, Yhim HY, Bang SM Tags: J Korean Med Sci Source Type: research

The Measles Strikes Back.
PMID: 30787684 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - February 18, 2019 Category: General Medicine Authors: Kang JH, Yoo JH Tags: J Korean Med Sci Source Type: research

Acute Cholecystitis in Elderly Patients after Hip Fracture: a Nationwide Cohort Study.
Conclusion: Incidence of acute cholecystitis in elderly patients after hip fracture within 30 days after the index date was 0.24%. Acute cholecystitis in elderly hip fracture patients dramatically increases the 30-day mortality rate by 4.35-fold. Therefore, early disease detection and management are crucial for patients. PMID: 30718989 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - February 4, 2019 Category: General Medicine Authors: Jang SY, Cha YH, Mun YS, Kim SH, Kim HY, Choy WS Tags: J Korean Med Sci Source Type: research

Alendronate-Anionic Clay Nanohybrid for Enhanced Osteogenic Proliferation and Differentiation.
Conclusion: The present AL-LDH could be considered as a promising DDS for improving efficacy of AL. PMID: 30718990 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - February 4, 2019 Category: General Medicine Authors: Piao H, Kim MH, Cui M, Choi G, Choy JH Tags: J Korean Med Sci Source Type: research

Psychiatric Symptoms and Clinical Diagnosis in High School Students Exposed to the Sewol Ferry Disaster.
Conclusion: During the acute aftermath of the Sewol Ferry Disaster, volunteer psychiatrists were able to provide services. These services included psychiatric assessments, crisis counseling, psychological first aid, and referrals for ongoing care. More than half of the students were perceived to have a psychiatric diagnosis, and a substantial proportion of students needed further treatment. Future research should focus on the short- and long-term effects of psychiatric interventions and the characterization of post-disaster mental health needs and service provision patterns. PMID: 30718991 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - February 4, 2019 Category: General Medicine Authors: Oh JK, Lee MS, Bae SM, Kim E, Hwang JW, Chang HY, Lee J, Kim J, Lee CS, Park J, Bhang SY Tags: J Korean Med Sci Source Type: research

Neonatal Outcomes of Very Low Birth Weight Infants in Korean Neonatal Network from 2013 to 2016.
Conclusion: Despite overall improvements in neonatal outcomes, the survival and morbidity rates of more immature infants with GA 22-27 weeks need further improvement. Therefore, it would be necessary to develop more optimal treatment strategies and perform more active quality improvement to further improve neonatal outcomes of VLBWIs in Korea. PMID: 30718992 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - February 4, 2019 Category: General Medicine Authors: Lee JH, Noh OK, Chang YS, Korean Neonatal Network Tags: J Korean Med Sci Source Type: research

Ethical Reviewers are Essential for Scholarly Journals for Timely Processing of Submissions and Avoiding Retractions.
PMID: 30718993 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - February 4, 2019 Category: General Medicine Authors: Mehregan M Tags: J Korean Med Sci Source Type: research

Study Design for the 2016 Baseline Survey of a Health System Strengthening Project in Quoc Oai District, Hanoi, Vietnam.
Conclusion: This study design description provides the basic information about a baseline survey of a future prospective cohort (as a part of a collaborative project on strengthening the health system in Vietnam) to the prospective data user of this survey. PMID: 30718994 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - February 4, 2019 Category: General Medicine Authors: Hoang VM, Oh J, Nguyen BN, Dat LM, Lee JK, Tran TGH, Nguyen VH, Lee SP, Bang KS, Cho Y, Kim SY, Lee HY, Le QC, Choi N, Dinh TS, Luu NH Tags: J Korean Med Sci Source Type: research

Sandwich Trick for Kids and Cells.
PMID: 30718995 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - February 4, 2019 Category: General Medicine Authors: Chung MS Tags: J Korean Med Sci Source Type: research

The Necessity of the Judicial Hospitalization for Acutely Exacerbated Person with Severe Psychiatric Disorder.
PMID: 30718996 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - February 4, 2019 Category: General Medicine Authors: Noh JS Tags: J Korean Med Sci Source Type: research

Assessment of Hepatic Cytochrome P450 3A Activity Using Metabolic Markers in Patients with Renal Impairment.
Conclusion: Hepatic CYP3A activity may not be affected by renal impairment-induced accumulation of plasma indoxyl sulfate. PMID: 30595680 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 31, 2018 Category: General Medicine Authors: Kim AH, Yoon S, Lee Y, Lee J, Bae E, Lee H, Kim DK, Lee S, Yu KS, Jang IJ, Cho JY Tags: J Korean Med Sci Source Type: research

The Correlation of Serum Osteoprotegerin with Non-Traditional Cardiovascular Risk Factors and Arterial Stiffness in Patients with Pre-Dialysis Chronic Kidney Disease: Results from the KNOW-CKD Study.
Conclusion: Non-traditional, kidney-related cardiovascular risk factors in addition to traditional cardiovascular risk factors were related to serum level of OPG in CKD. Serum OPG level was significantly related to baPWV. Our study suggests that kidney-related factors involved in CKD-specific pathways for VC play a role in the increased secretion of OPG into circulation in patients with CKD. Trial Registration: ClinicalTrials.gov Identifier: NCT01630486. PMID: 30595681 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 31, 2018 Category: General Medicine Authors: Chae SY, Chung W, Kim YH, Oh YK, Lee J, Choi KH, Ahn C, Kim YS Tags: J Korean Med Sci Source Type: research

End-stage Renal Disease and Risk of Active Tuberculosis: a Nationwide Population-Based Cohort Study.
Conclusion: We found that patients receiving dialysis for ESRD had an elevated risk of active TB. These results highlight the need for detailed and well-organised guidelines for active TB screening among patients with ESRD. PMID: 30595682 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 31, 2018 Category: General Medicine Authors: Min J, Kwon SK, Jeong HW, Han JH, Kim YJ, Kang M, Kang G Tags: J Korean Med Sci Source Type: research

Clinical Validation of a Protein Biomarker Panel for Non-Small Cell Lung Cancer.
Abstract We validated the diagnostic performance of a previously developed blood-based 7-protein biomarker panel, AptoDetect™-Lung (Aptamer Sciences Inc., Pohang, Korea) using modified aptamer-based proteomic technology for lung cancer detection. Non-small cell lung cancer (NSCLC), 200 patients and benign nodule controls, 200 participants were enrolled. In a high-risk population corresponding to ≥ 55 years of age and ≥ 30 pack-years, the diagnostic performance was improved, showing 73.3% sensitivity and 90.5% specificity with an area under the curve of 0.88. AptoDetect™-Lung (Aptamer Sciences Inc...
Source: J Korean Med Sci - December 31, 2018 Category: General Medicine Authors: Jung YJ, Oh IJ, Kim Y, Jung JH, Seok M, Lee W, Park CK, Lim JH, Kim YC, Kim WS, Choi CM Tags: J Korean Med Sci Source Type: research

Building Linked Big Data for Stroke in Korea: Linkage of Stroke Registry and National Health Insurance Claims Data.
Conclusion: We could establish big data on stroke by linking CRCS registry and HIRA records, using claims data without personal identifiers. We plan to conduct national stroke research and improve stroke care using the linked big database. PMID: 30595684 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 31, 2018 Category: General Medicine Authors: Kim TJ, Lee JS, Kim JW, Oh MS, Mo H, Lee CH, Jeong HY, Jung KH, Lim JS, Ko SB, Yu KH, Lee BC, Yoon BW Tags: J Korean Med Sci Source Type: research

Considering Revision the Criteria for Patients under Investigations for MERS-CoV Infections: Diarrhea or Not.
PMID: 30595685 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 31, 2018 Category: General Medicine Authors: Kim MN, Kim EC Tags: J Korean Med Sci Source Type: research

Association of Sleep Duration and Obesity According to Gender and Age in Korean Adults: Results from the Korea National Health and Nutrition Examination Survey 2007-2015.
Conclusion: This study demonstrated a significant association between sleep duration and obesity, which varied according to gender and age. PMID: 30595686 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 31, 2018 Category: General Medicine Authors: Cho KH, Cho EH, Hur J, Shin D Tags: J Korean Med Sci Source Type: research

An Atypical Case of Middle East Respiratory Syndrome in a Returning Traveler to Korea from Kuwait, 2018.
We report a case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection in a 61-year-old businessman returning from Kuwait. The patient arrived there on August 16, 2018, developed watery diarrhea on August 28 (day 0), and came back to Korea on September 7 (day 10) as his condition worsened. Upon arrival, he complained of diarrhea and weakness, but denied any respiratory symptoms, and he directly went to visit an emergency room. Chest radiography revealed interstitial infiltrates in the lungs, and he was immediately transferred to an isolation unit. Quantitative real-time PCR analysis of sputum samples taken o...
Source: J Korean Med Sci - December 31, 2018 Category: General Medicine Authors: Bak SL, Jun KI, Jung J, Kim JH, Kang CK, Park WB, Kim NJ, Oh MD Tags: J Korean Med Sci Source Type: research

Current Status of Human Papillomavirus Infection and Introduction of Vaccination to the National Immunization Program in Korea: an Overview.
Abstract Human Papillomavirus (HPV) infection is the most common sexually transmitted infection and is associated with the development of cervical cancer. The purpose of this report is to provide the literature evidences on selecting the HPV vaccine for national immunization program (NIP) in Korea. To complete these tasks, we reviewed domestic and foreign literature on the current status of HPV infection, efficacy and effectiveness of HPV vaccine, safety of vaccine and cost effectiveness analysis of vaccination business. Given that the median age of first sexual intercourse is continuing to fall, this may have ser...
Source: J Korean Med Sci - December 24, 2018 Category: General Medicine Authors: Kim MA, Han GH, Kim JH, Seo K Tags: J Korean Med Sci Source Type: research

Prognosis of Spontaneous Bacterial Peritonitis in Hepatocellular Carcinoma Patients.
Conclusion: Prognosis of SBP in HCC patients is relatively less severe. This result may be related with reduced antibiotics resistance and lower development rates of other complications, such as hepatic encephalopathy. Degree of systemic inflammation may be the most important factor for in-hospital mortality. PMID: 30584413 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 24, 2018 Category: General Medicine Authors: Kim JH, Choe WH, Kwon SY, Yoo BC Tags: J Korean Med Sci Source Type: research

Mucosal Immunity Related to FOXP3+ Regulatory T Cells, Th17 Cells and Cytokines in Pediatric Inflammatory Bowel Disease.
Abstract Background: We aimed to investigate mucosal immunity related to forkhead box P3 (FOXP3+) regulatory T (Treg) cells, T helper 17 (Th17) cells and cytokines in pediatric inflammatory bowel disease (IBD). Methods: Mucosal tissues from terminal ileum and colon and serum samples were collected from twelve children with IBD and seven control children. Immunohistochemical staining was done using anti-human FOXP3 and anti-RORγt antibodies. Serum levels of cytokines were analyzed using a multiplex assay covering interleukin (IL)-1β, IL-4, IL-6, IL-10, IL-17A/F, IL-21, IL-22, IL-23, IL-25, IL-31, IL...
Source: J Korean Med Sci - December 24, 2018 Category: General Medicine Authors: Cho J, Kim S, Yang DH, Lee J, Park KW, Go J, Hyun CL, Jee Y, Kang KS Tags: J Korean Med Sci Source Type: research

Detection of Innate and Artificial Mitochondrial DNA Heteroplasmy by Massively Parallel Sequencing: Considerations for Analysis.
Conclusion: In addition to the general accuracy of the MPS application on detecting heteroplasmy, our study indicates that the understanding of the nature of mitochondrial DNA and analysis algorithm would be crucial for appropriate interpretation of MPS results. PMID: 30584415 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 24, 2018 Category: General Medicine Authors: Kim MY, Cho S, Lee JH, Seo HJ, Lee SD Tags: J Korean Med Sci Source Type: research

A Brief Screening Tool for PTSD: Validation of the Korean Version of the Primary Care PTSD Screen for DSM-5 (K-PC-PTSD-5).
Abstract The purpose of this study was to develop and evaluate psychometrically the Korean version of the Primary Care Posttraumatic Stress Disorder Screen for the Diagnostic and Statistical Manual-fifth edition (K-PC-PTSD-5). In total, 252 participants were interviewed with the Structured Clinical Interview for Diagnostic and Statistical Manual-fifth edition-research version (SCID-5-RV). The K-PC-PTSD-5 showed good internal consistency (α = 0.872), test-retest reliability (r = 0.89), and concurrent validity (r = 0.81). A score of 3 was identified as the threshold for clinically significant posttraumatic str...
Source: J Korean Med Sci - December 24, 2018 Category: General Medicine Authors: Jung YE, Kim D, Kim WH, Roh D, Chae JH, Park JE Tags: J Korean Med Sci Source Type: research

Causes of Chronic Hip Pain Undiagnosed or Misdiagnosed by Primary Physicians in Young Adult Patients: a Retrospective Descriptive Study.
Conclusion: Most (> 80%) young patients with hip pain, a difficult issue to diagnosis for many primary physicians, had FAI syndrome, HD, spine lesions, and SpA. This study could give a chance to feedback information about cases with un- or mis-diagnosed hip pain, and it suggests that primary physicians need to be familiar with the diagnostic approach for these 4 diseases. PMID: 30584417 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 24, 2018 Category: General Medicine Authors: Lee YJ, Kim SH, Chung SW, Lee YK, Koo KH Tags: J Korean Med Sci Source Type: research

Treat-to-Target Strategy for Asian Patients with Early Rheumatoid Arthritis: Result of a Multicenter Trial in Korea.
Abstract Background: To evaluate the therapeutic benefits of the treat-to-target (T2T) strategy for Asian patients with early rheumatoid arthritis (RA) in Korea. Methods: In a 1-year, multicenter, open-label strategy trial, 346 patients with early RA were recruited from 20 institutions across Korea and stratified into 2 groups, depending on whether they were recruited by rheumatologists who have adopted the T2T strategy (T2T group) or by rheumatologists who provided usual care (non-T2T group). Data regarding demographics, rheumatoid factor titer, anti-cyclic citrullinated peptide antibody titer, disease activ...
Source: J Korean Med Sci - December 24, 2018 Category: General Medicine Authors: Song JJ, Song YW, Bae SC, Cha HS, Choe JY, Choi SJ, Kim HA, Kim J, Kim SS, Lee CK, Lee J, Lee SH, Lee SS, Lee SK, Lee SW, Park SH, Park W, Shim SC, Suh CH, Yoo B, Yoo DH, Yoo WH Tags: J Korean Med Sci Source Type: research

Exploring the Differences between Adolescents' and Parents' Ratings on Adolescents' Smartphone Addiction.
Conclusion: The results suggest that clinicians need to consider both adolescents' and parents' reports when assessing adolescents' smartphone addiction, and be aware of the possibility of under- or overestimation. Our results cannot only be a reference in assessing adolescents' smartphone addiction, but also provide inspiration for future studies. PMID: 30584419 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 24, 2018 Category: General Medicine Authors: Youn H, Lee SI, Lee SH, Kim JY, Kim JH, Park EJ, Park JS, Bhang SY, Lee MS, Lee YJ, Choi SC, Choi TY, Lee AR, Kim DJ Tags: J Korean Med Sci Source Type: research