Pulmonary Histoplasmosis Identified by Video-Assisted Thoracic Surgery (VATS) Biopsy: a Case Report.
In conclusion, we report a case of an immunocompetent patient who developed histoplasmosis in Korea. When a patient shows unexplainable progressive infiltrative lung lesions, histoplasmosis should be considered as one of differential diagnoses although Korea is not an endemic area. PMID: 29215824 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - December 8, 2017 Category: General Medicine Authors: Lee YJ, Kang HR, Song JH, Sin S, Lee SM Tags: J Korean Med Sci Source Type: research

Increasing Burden of Nontuberculous Mycobacteria in Korea.
PMID: 28665053 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Kee SJ, Suh SP Tags: J Korean Med Sci Source Type: research

Dysphagia due to Upper Esophageal Sphincter Disorder after Suicide Attempts.
PMID: 28665054 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Park MJ, Jung AR, Eun YG, Kim DH, Chung SH, Lee YC Tags: J Korean Med Sci Source Type: research

Plagiarism in the Context of Education and Evolving Detection Strategies.
This article analyses Scopus-based publication activity and evidence on poor writing, lack of related training, emerging anti-plagiarism strategies, and new forms of massive wasting of resources by publishing largely recycled items, which evade the 'red flags' of similarity checks. In some non-Anglophone countries 'copy-and-paste' writing still plagues pre- and postgraduate education. Poor research management, absence of courses on publication ethics, and limited access to quality sources confound plagiarism as a cross-cultural and multidisciplinary phenomenon. Over the past decade, the advent of anti-plagiarism software c...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Gasparyan AY, Nurmashev B, Seksenbayev B, Trukhachev VI, Kostyukova EI, Kitas GD Tags: J Korean Med Sci Source Type: research

Improvement in the Survival Rates of Very Low Birth Weight Infants after the Establishment of the Korean Neonatal Network: Comparison between the 2000s and 2010s.
In conclusion, the SRs of the VLBWIs and ELBWIs improved in the 2010s compared with those in the 2000s in Korea. This improvement is considered to have been related to the role of the KNN built in 2013. However, the latest VLBWI and ELBWI SRs in 2015 are still low compared with those in Japan, Australia and New Zealand, Canada, and Europe. In the future, we must establish and develop the tasks that are presented as future tasks in this review. PMID: 28665056 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Chung SH, Bae CW Tags: J Korean Med Sci Source Type: research

Publication Delay of Korean Medical Journals.
Abstract Publication lag is a determinant to journal efficiency that was not yet studied concerning Korean medical journals. To measure publication lag, we investigated the publication timestamps of 4,762 articles published by 10 Korean medical journals indexed in Scopus database, randomly selected from the KoreaMed Synapse since 2013. The total publication lag was 246.5 (Q1, Q3; 178.0, 347.0) days. The overall acceptance lag was 102.0 (65.0, 149.0) days. The overall lead lag was 123.0 (63.0, 236.0) days. The year of publication did not significantly affect the acceptance lag (P = 0.640), supposedly shortening it ...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Lee Y, Kim K, Lee Y Tags: J Korean Med Sci Source Type: research

Decoding Saccadic Directions Using Epidural ECoG in Non-Human Primates.
Abstract A brain-computer interface (BCI) can be used to restore some communication as an alternative interface for patients suffering from locked-in syndrome. However, most BCI systems are based on SSVEP, P300, or motor imagery, and a diversity of BCI protocols would be needed for various types of patients. In this paper, we trained the choice saccade (CS) task in 2 non-human primate monkeys and recorded the brain signal using an epidural electrocorticogram (eECoG) to predict eye movement direction. We successfully predicted the direction of the upcoming eye movement using a support vector machine (SVM) with the ...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Lee J, Choi H, Lee S, Cho BH, Ahn KH, Kim IY, Lee KM, Jang DP Tags: J Korean Med Sci Source Type: research

Occupational Risk of Latent Tuberculosis Infection in Health Workers of 14 Military Hospitals.
This study suggests that military health workers working with TB patients should be regularly examined by chest radiography, TST and IGRA to detect LTBI in the early stage and control nosocomial infection of TB. PMID: 28665059 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Yoon CG, Oh SY, Lee JB, Kim MH, Seo Y, Yang J, Bae KJ, Hong S, Yang ES, Kim HJ Tags: J Korean Med Sci Source Type: research

Clinical Impacts of Donor Types of Living vs. Deceased Donors: Predictors of One-Year Mortality in Patients with Liver Transplantation.
This study was performed for liver transplant recipients between May 2010 and December 2014 at the Pusan National University Yangsan Hospital. A total of 185 recipients who underwent LT were analyzed. Of the 185 recipients, 109 (58.9%) belonged to the living donor liver transplantation (LDLT) group. The median age was 52.4 years. LDLT recipients had lower model for end-stage liver disease (MELD) score compared with better liver function than deceased donor liver transplantation (DDLT) recipients (mean ± standard deviation [SD], 12.5 ± 8.3 vs. 24.9 ± 11.7, respectively; P
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Kim EJ, Lim S, Chu CW, Ryu JH, Yang K, Park YM, Choi BH, Lee TB, Lee SJ Tags: J Korean Med Sci Source Type: research

Recovery Rates of Non-Tuberculous Mycobacteria from Clinical Specimens Are Increasing in Korean Tertiary-Care Hospitals.
This study investigated the epidemiologic trends of NTM recovery from various clinical specimens in 2 Korean tertiary-care hospitals. We reviewed the laboratory records of patient samples cultured for mycobacteria between 2009 and 2015 at 2 tertiary-care hospitals in Korea. The medical records for patients with positive NTM samples were also reviewed. During the study period, 144,540 specimens were cultured for mycobacteria. The proportion of NTM-positive samples increased from 23.3% in 2009 to 48.2% in 2015. The 2 most frequently isolated NTM were Mycobacterium intracellulare (38.3%) and M. avium (23.1%). The number of cl...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Kim N, Yi J, Chang CL Tags: J Korean Med Sci Source Type: research

Metabolic Complications among Korean Patients with HIV Infection: The Korea HIV/AIDS Cohort Study.
In conclusion, proper diagnosis and management should be offered for the prevalent metabolic complications of Korean HIV-infected patients. Further studies on risk factors for metabolic complications are needed. PMID: 28665062 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Oh DH, Ahn JY, Kim SI, Kim MJ, Woo JH, Kim WJ, Baek JH, Kim SW, Choi BY, Lee MH, Choi JY, Han MG, Kang C, Kim JM, Choi JY, Korea HIV/AIDS Cohort Study Tags: J Korean Med Sci Source Type: research

Uric Acid Level Has a U-shaped Association with Clinical Outcomes in Patients with Vasospastic Angina.
Abstract No data are available on the association of serum uric acid and vasospastic angina (VSA) which has endothelial dysfunction as a possible pathophysiologic mechanism. Low uric acid level might cause adverse outcomes in VSA in connection with endothelial dysfunction. We enrolled 818 VSA patients whose uric acid level was measured at admission. Patients were categorized according to tertiles of uric acid level: group I, ≤ 4.8 mg/dL; group II, 4.9-5.9 mg/dL; and group III, ≥ 6.0 mg/dL. Primary outcome was major adverse cardiac events (MACEs), defined as a composite of cardiac death, acute myocardial infa...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Gwag HB, Yang JH, Park TK, Song YB, Hahn JY, Choi JH, Lee SH, Gwon HC, Choi SH Tags: J Korean Med Sci Source Type: research

Is Colonoscopic Screening Necessary for Patients Younger than 50 Years with Gastric Adenoma or Cancer?
Abstract Patients, aged ≥ 50 years, with gastric neoplasm are reported to be at increased risk for colorectal neoplasia (CRN), while data regarding the risk of CRN in young patients, aged
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Kim NH, Park JH, Park DI, Sohn CI, Jung YS Tags: J Korean Med Sci Source Type: research

Prophylactic versus Early Rescue Surfactant Treatment in Preterm Infants Born at Less than 30 Weeks Gestation or with Birth Weight Less than or Equal 1,250 Grams.
Abstract Prophylactic surfactant is known to be effective to reduce chronic lung disease in preterm infants compared with rescue surfactant treatment. In Korea, early prophylactic surfactant therapy was introduced in 2011. However, recently, the increased utilization of antenatal steroids and early stabilization through continuous positive airway pressure (CPAP) in the delivery room may have changed the risks and benefits of prophylactic surfactant therapy of infants at high risk of respiratory distress syndrome (RDS). We compared the effects and safety of prophylactic surfactant therapy (within 30 minutes after b...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Chun J, Sung SI, Ho YH, Kim J, Park GY, Yoon SA, Ahn SY, Chang YS, Park WS Tags: J Korean Med Sci Source Type: research

Comparison of Follow-up Courses after Discharge from Neonatal Intensive Care Unit between Very Low Birth Weight Infants with and without Home Oxygen.
Abstract In order to investigate the clinical impact of home oxygen use for care of premature infants, we compared the follow-up courses after neonatal intensive care unit (NICU) discharge between very low birth weight infants (VLBWIs) with and without home oxygen. We retrospectively identified 1,232 VLBWIs born at 22 to 32 weeks of gestation, discharged from the NICU of 43 hospitals in Korea between April 2009 and March 2010, and followed them up until April 2011. Clinical outcomes, medical service uses, and readmission and death rates during follow-up after the NICU discharge were compared between VLBWIs with (H...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Kim JS, Shim JW, Lee JH, Chang YS, Committee on Data Collection and Statistical Analysis, the Korean Society of Neonatology Tags: J Korean Med Sci Source Type: research

The Different Clinical Aspects of Pediatric Primary Airway Tumors in the Larynx, Trachea, and Bronchi.
This study suggests that we should consider different the locations in primary airway tumor based on the age at onset and diagnosis, initial symptoms or signs, and size of tumor. PMID: 28665067 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Cho HJ, Yoon J, Lee E, Lee YS, Kim SY, Roh JL, Kim DK, Choi SH, Park SI, Kim YH, Koh KN, Im HJ, Seo JJ, Hong SJ, Yu J Tags: J Korean Med Sci Source Type: research

Comparison of the Birth Statistics between Multi-cultural and Korean Families in Korea (2015).
This study compared the birth data of MCF and Korean families (KF) by geography, neonatal birth weight (BW), gestational age (GA), birth order of the neonates, place of delivery, cohabitation period of parents before the first child, and parental education level. The distribution of BW and the prevalence of low BW (
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Chung SH, Bae CW Tags: J Korean Med Sci Source Type: research

Trends in Fetal and Perinatal Mortality in Korea (2009-2014): Comparison with Japan and the United States.
In this study, we identified that the indices of fetal deaths in Korea are improving rapidly. In order to maintain this trend, improvement of perinatal care level and stronger national medical support policies should be maintained continuously. PMID: 28665069 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Song YH, Lee GM, Yoon JM, Cheon EJ, Lee SK, Chung SH, Lim JW Tags: J Korean Med Sci Source Type: research

Identification of Downstream Genes of the mTOR Pathway that Predict Recurrence and Progression in Non-Muscle Invasive High-Grade Urothelial Carcinoma of the Bladder.
Abstract Microarray analysis was used to investigate the lack of identified mammalian target of rapamycin (mTOR) pathway downstream genes to overcome cross-talk at non-muscle invasive high-grade (HG)-urothelial carcinoma (UC) of the bladder, gene expression patterns, gene ontology, and gene clustering by triple (p70S6K, S6K, and eIF4E) small interfering RNAs (siRNAs) or rapamycin in 5637 and T24 cell lines. We selected mTOR pathway downstream genes that were suppressed by siRNAs more than 2-fold, or were up-regulated or down-regulated by rapamycin more than 2-fold. We validated mTOR downstream genes with immunohis...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Jin S, Chang IH, Kim JW, Whang YM, Kim HJ, Hong SA, Lee TJ Tags: J Korean Med Sci Source Type: research

Feasibility and Safety of Mild Therapeutic Hypothermia in Poor-Grade Subarachnoid Hemorrhage: Prospective Pilot Study.
Abstract Therapeutic hypothermia (TH) improves the neurological outcome in patients after cardiac arrest and neonatal hypoxic brain injury. We studied the safety and feasibility of mild TH in patients with poor-grade subarachnoid hemorrhage (SAH) after successful treatment. Patients were allocated randomly to either the TH group (34.5°C) or control group after successful clipping or coil embolization. Eleven patients received TH for 48 hours followed by 48 hours of slow rewarming. Vasospasm, delayed cerebral ischemia (DCI), functional outcome, mortality, and safety profiles were compared between groups. We enr...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Choi W, Kwon SC, Lee WJ, Weon YC, Choi B, Lee H, Park ES, Ahn R Tags: J Korean Med Sci Source Type: research

The Relationship between Physical Activity Intensity and Mental Health Status in Patients with Breast Cancer.
Abstract The aim of this study was to investigate the correlation between physical activity (PA) level and mental health status in a population-based sample of Korean female patients with breast cancer. Our analysis included 76 patients with breast cancer and 44 healthy controls. The Korean versions of the International Physical Activity Questionnaire (IPAQ), Beck Depressive Inventory (BDI), State-Trait Anxiety Inventory-KY (STAI-KY), and Somatosensory Amplification Scale (SSAS), and Quality of Life (QOL) scale were assessed. The frequency of moderate PA level in breast cancer patients was significantly lower than...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Kang KD, Bae S, Kim HJ, Hwang IG, Kim SM, Han DH Tags: J Korean Med Sci Source Type: research

Sebaceous Carcinoma: Clinicopathologic Analysis of 29 Cases in a Tertiary Hospital in Korea.
Abstract Sebaceous carcinoma (SC) is a neoplasm derived from the adnexal epithelium of the sebaceous glands, and most studies on this neoplasm have been conducted in Caucasians. We retrospectively reviewed the records of 29 patients with SC (16 extraocular and 13 ocular lesions) who were diagnosed from 2001 to 2014 to analyze the clinical and histopathological features of SC in the Korean population. Sixteen of the patients were women and 13 were men. There was an equal sex distribution for extraocular lesions, and a female predilection (M:F = 1:1.6) for ocular lesions. The mean ages at presentation of extraocular...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Park SK, Park J, Kim HU, Yun SK Tags: J Korean Med Sci Source Type: research

Clinical Features of Atopic Dermatitis in Adults Are Different according to Onset.
Abstract Few studies of atopic dermatitis (AD) in adult patients have evaluated differences in clinical features of AD according to onset age. We aimed to characterize the clinical features of AD in adult patients according to age of onset. Subjects with AD outpatient visiting the Department of Dermatology at Kangnam Sacred Heart Hospital were recruited for this study. A dermatologist conducted clinical evaluation, a survey of demographics, and onset of AD-associated signs and symptoms for each participant. Total immunoglobulin E (IgE) was also tested. A total of 280 adult AD patients were enrolled, among which 23...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Son JH, Chung BY, Kim HO, Park CW Tags: J Korean Med Sci Source Type: research

Rapid Health Needs Assessment after Typhoons Bolaven and Tembin Using the Public Health Assessment for Emergency Response Toolkit in Paju and Jeju, Korea 2012.
Abstract Following natural disasters, rapid health needs assessments are required to quickly assess health status and help decision making during the recovery phase. The Korean Centers for Disease Control and Prevention (KCDC) developed the Public Health Assessment for Emergency Response (PHASER) Toolkit which was optimized for a weather disaster in Korea. The goal of this study is to assess public health needs following the 2012 typhoons Bolaven and Tembin in both urban and rural areas in Korea. We conducted pilot trials using the PHASER toolkit to assess health needs following typhoons Bolaven and Tembin in Paju...
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Hong KJ, Song KJ, Shin SD, Song SW, Ro YS, Jeong J, Kim TH, Lee YJ, Kim M, Jo SN, Kim MY Tags: J Korean Med Sci Source Type: research

Congenital Syphilis Presenting with Only Nephrotic Syndrome: Reemergence of a Forgotten Disease.
We report a 2-month-old infant with CS who presented with only nephrotic syndrome (NS). The previously healthy infant presented with NS and showed no other syphilitic manifestations. Remission of the NS was achieved with adequate penicillin treatment. No recurrence of proteinuria was observed during the 1 year of follow-up. Although rare, this long forgotten disease continues to affect pregnant women, resulting in prenatal or postnatal mortality. We still consider the possibility of syphilitic nephropathy and therefore serologic testing for congenital NS. PMID: 28665076 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Kim YH, Song JH, Kim CJ, Yang EM Tags: J Korean Med Sci Source Type: research

Letter to the Editor: Plagiarism in Scientific Writings: Is There Any Way Out?
PMID: 28665077 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Debnath J Tags: J Korean Med Sci Source Type: research

Letter to the Editor: Appropriate Statistical Analysis and Research Reporting.
PMID: 28665078 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Misra DP, Wakhlu A, Agarwal V, Sharma A, Negi VS Tags: J Korean Med Sci Source Type: research

Letter to the Editor: Sharing Image Data from Clinical Trials.
PMID: 28665079 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - July 1, 2017 Category: General Medicine Authors: Ko Y, Kim KW, Lee KJ, Lee KH Tags: J Korean Med Sci Source Type: research

Manuscript Submission Invitations from 'Predatory Journals': What Should Authors Do?
hmaus-Klughammer AE, Tekle BT Abstract Press freedom and worldwide internet access have opened ample opportunity for a staggering number of poor open access journals and junk publishers to emerge. Dubious publishers are abusing and camouflaging the golden open access model. In 2012, Jeffery Beall shed light on the predatory journals (as he preferred to call them) and the threat to open access scientific publication. Publishing in predatory journals is continuing to be a major threat for the development of science in developing countries. The authors of this article proposed solutions and outline a fresh perspectiv...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Authors Do? Tags: J Korean Med Sci Source Type: research

Predatory Publishing Is a Threat to Non-Mainstream Science.
This article highlights the issue of wasteful publishing practices that primarily affect non-mainstream science countries and rapidly growing academic disciplines. Numerous start-up open access publishers with soft or nonexistent quality checks and huge commercial interests have created a global crisis in the publishing market. Their publishing practices have been thoroughly examined, leading to the blacklisting of many journals by Jeffrey Beall. However, it appears that some subscription journals are also falling short of adhering to the international recommendations of global editorial associations. Unethical editing age...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Gasparyan AY, Nurmashev B, Udovik EE, Koroleva AM, Kitas GD Tags: J Korean Med Sci Source Type: research

Towards Actualizing the Value Potential of Korea Health Insurance Review and Assessment (HIRA) Data as a Resource for Health Research: Strengths, Limitations, Applications, and Strategies for Optimal Use of HIRA Data.
We present the characteristics and structure of HIRA data. We discuss strengths and limitations that should be considered in conducting research with HIRA data and suggest strategies for optimal utilization of HIRA data by reviewing published research using HIRA data. PMID: 28378543 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Kim JA, Yoon S, Kim LY, Kim DS Tags: J Korean Med Sci Source Type: research

Effects of CYP2C19 Genetic Polymorphisms on PK/PD Responses of Omeprazole in Korean Healthy Volunteers.
Abstract The aim of this study was to examine the effects of CYP2C19*2 and *3 genetic polymorphisms on omeprazole pharmacokinetic (PK) and pharmacodynamic (PD) responses. Twenty-four healthy Korean volunteers were enrolled and given 20 mg omeprazole orally once daily for 8 days. The genotypes of CYP2C19 single nucleotide polymorphisms (SNPs) (*2, *3, and *17) were screened. The plasma concentrations of omeprazole, omeprazole sulfone, and 5-hydroxy (5-OH) omeprazole were determined by liquid chromatography with tandem mass spectrometry (LC-MS/MS). The noncompartmental method was used for the determination of PK par...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Park S, Hyun YJ, Kim YR, Lee JH, Ryu S, Kim JM, Oh WY, Na HS, Lee JG, Seo DW, Hwang IY, Park Z, Jang IJ, Oh J, Choi SE Tags: J Korean Med Sci Source Type: research

Opsonophagocytic Antibodies to Serotype Ia, Ib, and III Group B Streptococcus among Korean Infants and in Intravenous Immunoglobulin Products.
Abstract Group B streptococcus (GBS) infection is a leading cause of sepsis and meningitis among infants, and is associated with high rates of morbidity and mortality in many countries. Protection against GBS typically involves antibody-mediated opsonization by phagocytes and complement components. The present study evaluated serotype-specific functional antibodies to GBS among Korean infants and in intravenous immunoglobulin (IVIG) products. An opsonophagocytic killing assay (OPA) was used to calculate the opsonization indices (OIs) of functional antibodies to serotypes Ia, Ib, and III in 19 IVIG products from 5 ...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Kim HW, Lee JH, Cho HK, Lee H, Seo HS, Lee S, Kim KH Tags: J Korean Med Sci Source Type: research

Clinical and Epidemiologic Characteristics of Spreaders of Middle East Respiratory Syndrome Coronavirus during the 2015 Outbreak in Korea.
Abstract Nosocomial transmission is an important characteristic of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection. Risk factors for transmission of MERS-CoV in healthcare settings are not well defined. During the Korean outbreak in 2015, 186 patients had laboratory-confirmed MERS-CoV infection. Those suspected as a source of viral transmission were categorized into the spreader groups (super-spreader [n = 5] and usual-spreader [n = 10]) and compared to the non-spreader group (n = 171). Body temperature of ≥ 38.5°C (adjusted odds ratio [aOR], 5.54; 95% confidence interval [CI], 1.38-22.30;...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Kang CK, Song KH, Choe PG, Park WB, Bang JH, Kim ES, Park SW, Kim HB, Kim NJ, Cho SI, Lee JK, Oh MD Tags: J Korean Med Sci Source Type: research

Deficiencies of Circulating Mucosal-associated Invariant T Cells and Natural Killer T Cells in Patients with Multiple Trauma.
This study shows numerical deficiencies of circulating MAIT cells and NKT cells in multiple trauma. In addition, these invariant T cell deficiencies were found to be associated with disease severity. These findings provide important information for predicting the prognosis of multiple trauma. PMID: 28378547 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Jo YG, Choi HJ, Kim JC, Cho YN, Kang JH, Jin HM, Kee SJ, Park YW Tags: J Korean Med Sci Source Type: research

Effect of Coenzyme Q10 on Radiation Nephropathy in Rats.
Abstract The kidney is one of the most radiosensitive organs in the abdominal cavity and is the dose-limiting structure in cancer patients receiving abdominal or total body irradiation. In the present study, the effect of coenzyme Q10 (CoQ10) on radiation nephropathy was evaluated in rats. A total of 72 rats were equally randomized into 4 groups: Control, CoQ10, irradiation with 10 Gy (RT) + placebo, or RT + CoQ10. The 2 RT groups received single 10 Gy of abdominal irradiation. The 2 CoQ10 groups were supplemented daily with 1 mL of soybean oil containing 10 mg/kg of CoQ10. The RT + placebo and control groups rece...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Ki Y, Kim W, Kim YH, Kim D, Bae JS, Park D, Jeon H, Lee JH, Lee J, Nam J Tags: J Korean Med Sci Source Type: research

Myxoid and Sarcomatoid Variants of Adrenocortical Carcinoma: Analysis of Rare Variants in Single Tertiary Care Center.
Abstract The aim of this study is to describe rare variants of adrenocortical carcinoma (ACC) and to compare the prognosis with that of conventional ACC. We retrospectively reviewed 8 cases of myxoid variant, 1 sarcomatoid variant, and 14 cases of conventional ACC, who underwent surgical resection at the Asan Medical Center between 1996 and 2014. An analysis of the clinicopathological characteristics, including the Weiss score, Ki-67 labeling index, and reticulin framework assessment is presented. The mean age of patients with myxoid/sarcomatoid ACC was 45 years; 4 out of 9 patients were women. Mean primary tumor ...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Sung TY, Choi YM, Kim WG, Lee YM, Kim TY, Shong YK, Kim WB, Song DE Tags: J Korean Med Sci Source Type: research

Discrepancies in Clinic and Ambulatory Blood Pressure in Korean Chronic Kidney Disease Patients.
In conclusion, ABPM revealed a high prevalence of non-/reverse-dippers and sustained/masked HT in Korean CKD patients. Clinicians should try to obtain a CKD patient's ABPM, especially among those who are older or who have advanced CKD as well as those with abnormal Ca × P product, iPTH, and albumin. PMID: 28378550 [PubMed - in process] (Source: J Korean Med Sci)
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Oh YK, Chin HJ, Ahn SY, An JN, Lee JP, Lim CS, Oh KH Tags: J Korean Med Sci Source Type: research

Changes in Urinary Angiotensinogen Associated with Deterioration of Kidney Function in Patients with Type 2 Diabetes Mellitus.
Abstract Urinary angiotensinogen (AGT) is potentially a specific biomarker for the status of the intrarenal renin-angiotensin system (RAS) in patients with diabetes mellitus. We explored whether changes in urinary AGT excretion levels were associated with the deterioration of kidney function in type 2 diabetes patients with preserved kidney function. Urinary baseline AGT levels were measured in 118 type 2 diabetic patients who were not taking RAS blockers and who had estimated glomerular filtration rates (eGFRs) ≥ 60 mL/min/1.73 m². A total of 91 patients were followed-up for 52 months. Changes in urinary ...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Lee MJ, Kim SS, Kim IJ, Song SH, Kim EH, Seo JY, Kim JH, Kim S, Jeon YK, Kim BH, Kim YK Tags: J Korean Med Sci Source Type: research

The Definition of Past Tuberculosis Affects the Magnitude of Association between Pulmonary Tuberculosis and Respiratory Dysfunction: Korea National Health and Nutrition Examination Survey, 2008-2012.
Abstract Tuberculosis (TB) is associated with an increased risk of chronic lung impairment. The aim of this study was to compare the clinical characteristics and lung functions according to definition of past TB. We used the population-based, Korea National Health and Nutrition Examination Survey (KNHANES) (2008-2012) to analyze 13,522 subjects age 40 years or older who underwent spirometry and chest X-ray (CXR). Subjects with TB lesions on CXR (with or without a history of TB) were older, more likely to be male, ever smokers, and of low socioeconomic status than subjects with only a history of TB or without evide...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Choi CJ, Choi WS, Lee SY, Kim KS Tags: J Korean Med Sci Source Type: research

Link between Serum Pepsinogen Concentrations and Upper Gastrointestinal Endoscopic Findings.
Abstract The serum pepsinogen (PG) assay findings are correlated with the status of Helicobacter pylori infection, but there are controversies on the link with upper gastrointestinal (UGI) endoscopic findings. The aim of this study was to determine the significance of a serum PG assay for correlating with endoscopic findings in H. pylori-seroprevalent adult population. Korean adults who visited for a health check-up were included consecutively. Subjects after gastrectomy or H. pylori eradication were excluded. After completing the serum PG assay and anti-H. pylori immunoglobulin G (IgG) titer on the same day of UG...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Lee SP, Lee SY, Kim JH, Sung IK, Park HS, Shim CS Tags: J Korean Med Sci Source Type: research

Reference Values and Utility of Serum Total Immunoglobulin E for Predicting Atopy and Allergic Diseases in Korean Schoolchildren.
Abstract The present study aimed to investigate the distribution of total serum immunoglobulin E (IgE) levels in Korean schoolchildren and to evaluate its utility in the prediction of atopy and allergic diseases. A nationwide, cross-sectional survey was conducted in first grade students from randomly selected elementary and middle schools. Total IgE levels were measured by ImmunoCAP. Skin prick tests were performed for 18 common inhalant allergens to determine the presence of atopy. Children aged 12-13 years and parents of children aged 6-7 years were asked to complete questionnaire assessing allergic diseases. Th...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Kim HY, Choi J, Ahn K, Hahm MI, Lee SY, Kim WK, Chae Y, Park YM, Han MY, Lee KJ, Kwon HJ, Kim S, Yoo H, Kim J Tags: J Korean Med Sci Source Type: research

A Single Center Analysis of the Positivity of Hepatitis B Antibody after Neonatal Vaccination Program in Korea.
Abstract The antibody to hepatitis B surface antigen (anti-HBs) seropositivity rate after 3 doses of hepatitis B virus (HBV) vaccination during infancy period is known to be higher than 90%. However, a considerable number of vaccines do not form protective anti-HBs or chronologic decrease of anti-HBs. We retrospectively collected data of HBV serologic test results in 20,738 individuals from 2000 to 2015. After exclusion criteria were applied, 19,072 individuals were included. We analyzed the anti-HBs seropositivity rate, anti-HBs disappearance rate, anti-HBs positive seroconversion rate after receiving a booster v...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Kim YJ, Li P, Hong JM, Ryu KH, Nam E, Chang MS Tags: J Korean Med Sci Source Type: research

RNA-Seq for Gene Expression Profiling of Human Necrotizing Enterocolitis: a Pilot Study.
Abstract Necrotizing enterocolitis (NEC) characterized by inflammatory intestinal necrosis is a major cause of mortality and morbidity in newborns. Deep RNA sequencing (RNA-Seq) has recently emerged as a powerful technology enabling better quantification of gene expression than microarrays with a lower background signal. A total of 10 transcriptomes from 5 pairs of NEC lesions and adjacent normal tissues obtained from preterm infants with NEC were analyzed. As a result, a total of 65 genes (57 down-regulated and 8 up-regulated) revealed significantly different expression levels in the NEC lesion compared to the ad...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Jung K, Koh I, Kim JH, Cheong HS, Park T, Nam SH, Jung SM, Sio CA, Kim SY, Jung E, Lee B, Kim HR, Shin E, Jung SE, Choi CW, Kim BI, Jung E, Shin HD Tags: J Korean Med Sci Source Type: research

Reference Values for the Revised Anti-M ├╝llerian Hormone Generation II Assay: Infertile Population-based Study.
Reference Values for the Revised Anti-Müllerian Hormone Generation II Assay: Infertile Population-based Study. J Korean Med Sci. 2017 May;32(5):825-829 Authors: Lee JY, Ahn S, Lee JR, Jee BC, Kim CH, Seo S, Suh CS, Kim SH Abstract Anti-Müllerian hormone (AMH) is now accepted as an important clinical marker of ovarian reserve and is increasingly measured as an initial evaluation at infertility clinics. The aim of this study was to establish reference values for the revised second generation (Gen II) assay using population-based data. In this population-based cohort study, AMH data from unsele...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Lee JY, Ahn S, Lee JR, Jee BC, Kim CH, Seo S, Suh CS, Kim SH Tags: J Korean Med Sci Source Type: research

Common Causes of Postmenopausal Bleeding in Korean Women: 10-Year Outcomes from a Single Medical Center.
Abstract The common causes of postmenopausal bleeding (PMB), according to the data from the western world, are atrophy, hormone replacement therapy (HRT), endometrial cancer, etc. We conducted a retrospective study to assess whether the causes of PMB in Korean postmenopausal women are similar to those already known. This retrospective study used 10-year medical records (March 2005 to December 2014) of 792 PMB women in the Yonsei University Health System. The data were divided into 2 categories by 5-year intervals to compare the differences between the 2 periods. The most common cause of PMB in Korean women was atr...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Kim MK, Jung YS, Chon SJ, Yun BH, Cho S, Choi YS, Lee BS, Seo SK Tags: J Korean Med Sci Source Type: research

Mortality in Schizophrenia and Other Psychoses: Data from the South Korea National Health Insurance Cohort, 2002-2013.
This study examined all-cause and suicide mortality rates in Korean patients diagnosed with schizophrenia, mood disorder, or mental and behavioral disorder due to psychoactive substance use and to compare this with that of the general population. Data were from the National Health Insurance cohort, 2002 to 2013. A total of 107,190 cases aged 15 years or over were included. Mortality rates per 100,000 person years (PY) were obtained. Poisson regression modelling was conducted to quantify the effect of baseline characteristics on all-cause and suicide mortality risks. Standardized mortality ratios (SMRs) were also calculated...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Kim W, Jang SY, Chun SY, Lee TH, Han KT, Park EC Tags: J Korean Med Sci Source Type: research

What Kind of Stress Is Associated with Depression, Anxiety and Suicidal Ideation in Korean Employees?
Abstract Various types of stress affect mental health in the form of mood disorders, anxiety disorders, and suicidal ideation. Recently, the increasing suicide rate in the working-age population has become a major mental health concern in Korea. Thus, we investigated what kind of stress influence depression, anxiety, and suicidal ideation in Korean employees. The study participants were 189,965 employees who attended health screenings and responded to the Center for Epidemiologic Study-Depression Scale, the Beck Anxiety Inventory, and a questionnaire on the major causes of stress and suicidal ideation. We investig...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Shin YC, Lee D, Seol J, Lim SW Tags: J Korean Med Sci Source Type: research

Comparison of Objective and Subjective Changes Induced by Multiple-Pinhole Glasses and Single-Pinhole Glasses.
Abstract Multiple-pinhole (MPH) glasses are currently sold in many countries with unproven advertisements; however, their objective and subjective effects have not been investigated. Therefore, to investigate the effects of MPH glasses excluding the single-pinhole (SPH) effect, we compared the visual functional changes, reading speed, and ocular discomfort after reading caused by MPH and SPH glasses. Healthy 36 participants with a mean age of 33.1 years underwent examinations of pupil size, visual acuity (VA), depth of focus (DOF), and near point accommodation (NPA); tests for visual field (VF), contrast sensitivi...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Kim WS, Park IK, Park YK, Chun YS Tags: J Korean Med Sci Source Type: research

Early Rehabilitation in Elderly after Arthroplasty versus Internal Fixation for Unstable Intertrochanteric Fractures of Femur: Systematic Review and Meta-Analysis.
Abstract The purpose of this study was to compare the outcomes focusing on the functional outcome and clinical results of replacement arthroplasty (AP) vs. internal fixation (IF) for the treatment of unstable intertrochanteric femoral fracture in elderly. Systematic review and meta-analysis were performed on 10 available clinical studies (2 randomized controlled trials and 8 comparative studies). Subgroup analysis was performed by type of methodological quality. Partial weight bearing time in AP group was earlier than that in IF group (SMD = -0.86; 95% CI = -0.42, 1.29; P = 0.050). The overall outcomes such as mor...
Source: J Korean Med Sci - April 6, 2017 Category: Journals (General) Authors: Yoo JI, Ha YC, Lim JY, Kang H, Yoon BH, Kim H Tags: J Korean Med Sci Source Type: research