Affordable Rapid Olfaction Measurement Array: A Novel, Essential Oil-Based Test Strongly Correlated with UPSIT and Subjective Outcome Measures.
We describe the creation of a novel, essential oil-based smell test, Affordable Rapid Olfaction Measurement Array (AROMA), composed at 14 scents at different concentrations and demonstrate correlation of AROMA with the University of Pennsylvania Smell Identification Test (UPSIT), patient age, Sinonasal Outcomes Test (SNOT-22), and perceived loss of smell. METHODS: AROMA was developed for point-of-care olfactory testing and compared to the UPSIT, as well as subjective outcome measures as noted above. About 37 healthy controls were prospectively recruited to assess the reliability of AROMA using a test-retest protocol. ...
Source: The Annals of Otology, Rhinology, and Laryngology - August 16, 2019 Category: ENT & OMF Authors: Villwock JA, Li J, Moore C, Chiu AG, Sykes KJ Tags: Ann Otol Rhinol Laryngol Source Type: research

Rhinotillexomania Manifesting as Empty Nose Syndrome.
CONCLUSION: This is the first report of rhinotillexomania manifesting with features of ENS. PMID: 31416334 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - August 16, 2019 Category: ENT & OMF Authors: Tranchito E, Chhabra N Tags: Ann Otol Rhinol Laryngol Source Type: research

Causative Factors for Complications in Transpalatal Advancement.
Abstract INTRODUCTION: Transpalatal advancement (TPA) is a procedure that is used when modern variants of uvulopharyn-gopalatoplasty are unable to provide enough anterior traction. Although successful in reduction of obstructive sleep apnea (OSA) parameters, it also comes with procedure-specific risks. Formation of an oro-nasal fistula (ONF) is a complication that results in significant morbidity and a protracted treatment course. METHODS: After approval from the University of Wollongong Health Research Ethics Committee, a retrospective chart review of all cases undergoing TPA performed by a single surgeon ov...
Source: The Annals of Otology, Rhinology, and Laryngology - August 13, 2019 Category: ENT & OMF Authors: Chan L, Kitpornchai L, Mackay S Tags: Ann Otol Rhinol Laryngol Source Type: research

Morphometric Differences in the Recurrent Laryngeal Nerve in Patients with Vocal Fold Paralysis.
CONCLUSIONS: The morphometric data presented here suggest that correlations between the time since onset of vocal fold paralysis and reinnervation outcomes may be due to fiber size changes in the paralyzed nerve over time. PMID: 31409113 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - August 13, 2019 Category: ENT & OMF Authors: Chao MR, Howe KA, Pierce JL, Stark AC, Smith ME, Christensen MB Tags: Ann Otol Rhinol Laryngol Source Type: research

Attitudes of Clinicians about Screening Head and Neck Cancer Survivors for Lung Cancer Using Low-Dose Computed Tomography.
CONCLUSIONS: While clinicians feel that LDCT LCS may benefit some HNC survivors, there are barriers both to implementing LCS SDM for these patients in primary care as currently recommended and to integrating it into cancer clinics. Challenges for SDM across settings include a lack of decision aids tailored to patients with cancer histories. Given recommendations to broaden LCS eligibility criteria, more research may be required before refinement of current guidelines. PMID: 31409114 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - August 13, 2019 Category: ENT & OMF Authors: Dukes K, Seaman AT, Hoffman RM, Christensen AJ, Kendell N, Sussman AL, Vélez-Bermúdez M, Volk RJ, Pagedar NA Tags: Ann Otol Rhinol Laryngol Source Type: research

Validation of the Maxillary Sinus Roof as a Landmark for Navigating the Pediatric Skull Base.
Abstract OBJECTIVE: To define a new anatomic relationship in pediatric sinus surgery, assessing the maxillary roof as a constant safe landmark to avoid skull base injury in the pediatric population. STUDY DESIGN: Retrospective analysis. SETTING: Tertiary care children hospital. SUBJECTS AND METHODS: A retrospective analysis was performed of all computed tomography scans of the sinuses and facial bones at the emergency department of a tertiary children's hospital over the course of a year. Radiographic measurements included the lowest cribriform plate and planum sphenoidale (PS) heights, or posterior...
Source: The Annals of Otology, Rhinology, and Laryngology - August 9, 2019 Category: ENT & OMF Authors: Evans SS, Banks C, Richman J, Woolley A, Cho DY, Woodworth B Tags: Ann Otol Rhinol Laryngol Source Type: research

Intranasal Septal Splints: Prophylactic Antibiotics and Nasal Microbiology.
CONCLUSIONS: Increased bacterial growth and emergence of resistant strains were observed on intranasal septal splints despite prophylactic antibiotic treatment. Nonetheless, this did not translate into clinical infection. Thus, considering antibiotics overuse and increasing bacterial resistance, further research is needed to determine the role of antibiotic prophylaxis in the setting of intranasal splints. PMID: 31390881 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - August 8, 2019 Category: ENT & OMF Authors: Ritter A, Alkan U, Yahav D, Soudry E, Reifen E Tags: Ann Otol Rhinol Laryngol Source Type: research

Caudal Septal Division and Interposition Batten Graft: A Novel Technique to Correct Caudal Septal Deviation in Septoplasty.
Abstract BACKGROUND: Correction of caudal septal deviation is a challenging task that may require multiple surgical approaches. OBJECTIVE: To introduce a novel technique - caudal septal division and interposition batten graft - and evaluate its surgical outcomes in patients undergoing correction of caudal septal deviation. METHOD: The surgical procedure includes a division of the deviated caudal L-strut preserved after resection of the deviated quadrangular septal cartilage at the central portion. A batten graft made of septal cartilage or bone is interposed between the cut ends of the caudal L-strut, th...
Source: The Annals of Otology, Rhinology, and Laryngology - August 6, 2019 Category: ENT & OMF Authors: Kim SA, Jang YJ Tags: Ann Otol Rhinol Laryngol Source Type: research

Clinical Analysis of Pediatric Thyroid Cancer: A Single Medical Institution Experience of 18  Years.
CONCLUSION: Pediatric thyroid cancer is relatively rare and should be considered a specific disease entity with respect to the thyroid cancer in adults, since there are several distinctive characteristics. PMID: 31375033 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - August 2, 2019 Category: ENT & OMF Authors: Byeon HK, Kim SB, Oh HS, Kim HK, Choi IH, Kim H, Cho JG, Oh KH, Baek SK, Woo JS, Kwon SY, Kim HY, Jung KY Tags: Ann Otol Rhinol Laryngol Source Type: research

Blast-Induced Cholesteatomas After Spontaneous Tympanic Membrane Healing.
CONCLUSIONS: BICs can develop behind intact tympanic membrane or along with TM perforation. Based on the current review, when a TM perforation and spontaneous healing were documented, after blast exposure, MRI scan is an integral component of the follow-up. The optimal timing for MRI performance after blast exposure, is yet to be identified. PMID: 31366214 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - August 1, 2019 Category: ENT & OMF Authors: Ungar OJ, Shilo S, Anat W, Cavel O, Handzel O, Oron Y Tags: Ann Otol Rhinol Laryngol Source Type: research

Cochlear-Vestibular Impairment due to West Nile Virus Infection.
CONCLUSIONS: In the light of our findings, a prospective study would be warranted on a large series of patients with WNV infection in order: (i) to better define the epidemiology of the related cochlear-vestibular involvement; and (ii) to elucidate the virus-related changes to peripheral and central auditory and vestibular functions. PMID: 31366220 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - August 1, 2019 Category: ENT & OMF Authors: Parrino D, Brescia G, Trimarchi MV, Tealdo G, Sasset L, Cattelan AM, Bovo R, Marioni G Tags: Ann Otol Rhinol Laryngol Source Type: research

Make-Up Therapy for Patients With Facial Nerve Palsy.
CONCLUSION: Make-up therapy to improve the symmetry of facial appearance could afford a noninvasive and low-cost treatment for patients with facial nerve palsy, especially in terms of patient quality of life and psychological condition. PMID: 31307215 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - July 18, 2019 Category: ENT & OMF Authors: Fujiwara K, Furuta Y, Aoki W, Nakamaru Y, Morita S, Hoshino K, Fukuda A, Homma A Tags: Ann Otol Rhinol Laryngol Source Type: research

Transoral Tubed Supraglottoplasty: A New Minimally Invasive Procedure for Aspiration.
CONCLUSION: TS is a minimally invasive procedure that can improve swallowing and reduce aspiration. PMID: 31311291 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - July 17, 2019 Category: ENT & OMF Authors: Ma Y, Naunheim MR, Gregory J, Woo P Tags: Ann Otol Rhinol Laryngol Source Type: research

Investigation of Novel Grafts in Use for Pediatric Tympanoplasty.
CONCLUSIONS: Similar rates of complications were observed among autografts, xenografts, and allografts, providing preliminary evidence that they are safe to use in pediatric tympanoplasty. PMID: 31304769 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - July 13, 2019 Category: ENT & OMF Authors: Barron C, Lukens J, Niermeyer W, Onwuka A, Chiang T, Elmaraghy C Tags: Ann Otol Rhinol Laryngol Source Type: research

Detection of Microbiota in Post Radiation Sinusitis.
CONCLUSION: The bacteriology of post radiation sinusitis appears to resemble the microorganisms responsible for chronic sinusitis in healthy adults. Next generation gene sequencing techniques may reveal additional organisms responsible for sinusitis and provide complementary results that may impact the medical treatment of post radiation sinusitis. PMID: 31304771 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - July 13, 2019 Category: ENT & OMF Authors: Stoddard TJ, Varadarajan VV, Dziegielewski PT, Boyce BJ, Justice JM Tags: Ann Otol Rhinol Laryngol Source Type: research

Quality of Voice and Prognostic Markers for the Recovery of Vocal Fold Paralysis After Thyroid Surgery.
This study is set to analyze clinicopathological factors predicting the recovery of unilateral vocal fold paralysis (UVP) in patients after thyroid gland surgery. The quality of voice was additionally assessed in these patients. METHODS: The charts and videolaryngostroboscopy (VLS) examinations of 84 consecutive patients with a complete UVP after surgery of the thyroid gland were retrospectively reviewed. Patients were divided into 2 groups: patients who fully recovered from vocal fold paralysis and those who failed to recover after a follow-up of 12 months. The quality of voice was analyzed among other things by dete...
Source: The Annals of Otology, Rhinology, and Laryngology - July 11, 2019 Category: ENT & OMF Authors: Reiter R, Heyduck A, Hoffmann TK, Brosch S, Buchberger MA, Schorer K, Weber T, Pickhard A Tags: Ann Otol Rhinol Laryngol Source Type: research

Spindle Cell Lipomas of the Respiratory Tract: A Case Report and Comprehensive Literature Review.
CONCLUSION: Although rare, SCLs may arise from throughout the respiratory tract and cause dyspnea, hoarseness and stridor. Spindle cell lipoma should be considered in the differential diagnosis of a respiratory tract mass. This diagnosis confers a good prognosis and patients may be reassured that surgery is almost always curative. PMID: 31291740 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - July 10, 2019 Category: ENT & OMF Authors: Reid J, Wehrli B, Sowerby LJ Tags: Ann Otol Rhinol Laryngol Source Type: research

Submental Island Flap: A Technical Update.
CONCLUSIONS: Manual blunt dissection of the mylohyoid muscle and its inclusion in the submental island flap increases efficiency and reliability. PMID: 31291743 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - July 10, 2019 Category: ENT & OMF Authors: Zenga J, Emerick KS, Deschler DG Tags: Ann Otol Rhinol Laryngol Source Type: research

Diagnostic Protocol for Detecting Otosclerosis on High-Resolution Temporal Bone CT.
CONCLUSIONS: This HRCT checklist is a highly accurate tool for evaluating the presence of OS when images are reviewed in the systematic fashion described. Imaging prior to surgery aids in counseling patients, preparing surgically, and excluding other pathologies. PMID: 31288548 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - July 9, 2019 Category: ENT & OMF Authors: Brown LA, Mocan BO, Redleaf MI Tags: Ann Otol Rhinol Laryngol Source Type: research

Direct Visualization of Laryngeal Mucociliary Clearance in Adults.
CONCLUSIONS: This is the first study visualizing the mucociliary clearance of the larynx. Ciliary directionality was consistent in the participants studied, with dye moving superolateral from the false cords to the aryepiglottic fold. Swallowing was an effective mechanism for clearance from the endolarynx, when the dye had reached the aryepiglottic fold. Future research can study potential alterations in laryngeal mucociliary clearance in chronic disease states. PMID: 31271035 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - July 4, 2019 Category: ENT & OMF Authors: O'Neil LM, Jefferson ND Tags: Ann Otol Rhinol Laryngol Source Type: research

Three Cases of Primary Ciliary Dyskinesia Combined With Reduced Exhaled Nitric Oxide.
CONCLUSION: Our report stresses the reliability of eNO measurement in the diagnosis of PCD, accompanied by clinical phenotypes and additional diagnostic tools, such as TEM analysis and genetic testing. PMID: 31271036 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - July 4, 2019 Category: ENT & OMF Authors: Han SM, Hwang CS, Jeon HJ, Lee HY, Cho HJ, Park DJ Tags: Ann Otol Rhinol Laryngol Source Type: research

Why Central Neck Dissection Works (and Fails) for Recurrent Thyroglossal Duct Remnants.
CONCLUSIONS: Central neck dissection in combination with a Sistrunk-type dissection of the tongue base is effective in the control of recurrent infection following unsuccessful Sistrunk surgery and aids in dissection for children with intractable infection. Although this technique reliably controls infrahyoid disease and improves access to the hyoid and posterior hyoid space, it does nothing to address the difficulties of following the thyroglossal tract into the tongue base. PMID: 31271039 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - July 4, 2019 Category: ENT & OMF Authors: Isaacson G, Kaplon A, Tint D Tags: Ann Otol Rhinol Laryngol Source Type: research

Awareness of European Otolaryngologists and General Practitioners Toward Laryngopharyngeal Reflux.
CONCLUSION: The majority of GPs and otolaryngologists do not believe themselves to be sufficiently informed about LPR, leading to different practice patterns and grey areas. The elaboration of international recommendations in the management of reflux is needed to improve practices. PMID: 31257901 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - July 1, 2019 Category: ENT & OMF Authors: Lechien JR, Mouawad F, Mortuaire G, Remacle M, Bobin F, Huet K, Nacci A, Barillari MR, Crevier-Buchman L, Hans S, Finck C, Akst LM, Karkos PD Tags: Ann Otol Rhinol Laryngol Source Type: research

Curved Laryngopharyngoscope With Flexible Next-Generation Robotic Surgical System for Transoral Hypopharyngeal Surgery: A Preclinical Evaluation.
CONCLUSIONS: These preclinical data suggest that using a curved laryngopharyngoscope in combination with a flexible robotic surgical system may lead to technical innovations concerning transoral surgery of the hypopharynx. PMID: 31220916 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 20, 2019 Category: ENT & OMF Authors: Eguchi K, Chan JYK, Tateya I, Shimizu A, Holsinger FC, Sugimoto T Tags: Ann Otol Rhinol Laryngol Source Type: research

Management of Vocal Fold Paralysis and Dysphagia for Neurologic Malignancies in Children.
CONCLUSIONS: Patients with vocal fold paralysis secondary to neurologic malignancy can have an improvement in speech and swallowing after a variety of treatments, including speech therapy or early injection laryngoplasty. There was no statistically significant difference in improvement based on the type of intervention utilized. A larger sample size is needed to conclude whether surgical intervention combined with speech therapy leads to more rapid and significant functional improvement than speech therapy alone. PMID: 31215235 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 19, 2019 Category: ENT & OMF Authors: Nagy P, Beckmann N, Cox S, Sheyn A Tags: Ann Otol Rhinol Laryngol Source Type: research

Unusual Nasal Insufficiency in an Infant: What's Behind the Nostril?
CONCLUSIONS: Even though there are very few cases in scientific literature of a tumor with these characteristics in infants, IMT must be present as a differential diagnosis of intranasal masses. The role of the pathologist is essential to reach the definitive diagnosis and the performance of an early surgical treatment decreases aesthetic consequences in this pathology. PMID: 31204488 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 16, 2019 Category: ENT & OMF Authors: Alzate Amaya F, Invencio da Costa LF, Martinez Moran A, Alvarez Rodriguez R Tags: Ann Otol Rhinol Laryngol Source Type: research

eHealth Literacy in Otolaryngology Patients.
CONCLUSIONS: Otolaryngology patients in a university town had better eHealth literacy than patients in more rural settings, suggesting that online medical resources and access points are less likely to be useful in rural populations. PMID: 31195809 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 13, 2019 Category: ENT & OMF Authors: Bailey CE, Kohler WJ, Makary C, Davis K, Sweet N, Carr M Tags: Ann Otol Rhinol Laryngol Source Type: research

Type I Posterior Glottic Stenosis: Natural History and In-Office Management.
CONCLUSIONS: This case illustrates the natural history of the development of PGS-I, demonstrates the feasibility of office-based management of this condition, and provides further evidence that lysis of PGS-I synechia does not uniformly lead to restoration of normal laryngeal function and mobility. PMID: 31161772 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 4, 2019 Category: ENT & OMF Authors: Silva Merea V, Sadoughi B Tags: Ann Otol Rhinol Laryngol Source Type: research

Small Cell Carcinoma in the Head and Neck.
CONCLUSIONS: ESmCCs of the head and neck have a poor prognosis, similar to those of carcinomas in many other sites. Control of distant metastasis would contribute to improving the prognosis of ESmCCs of the head and neck. Further studies are required for better understanding these disease entities and their response to treatment modalities. PMID: 31161776 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 4, 2019 Category: ENT & OMF Authors: Wakasaki T, Yasumatsu R, Masuda M, Matsuo M, Tamae A, Kubo K, Kogo R, Uchi R, Taura M, Nakagawa T Tags: Ann Otol Rhinol Laryngol Source Type: research

Revision Stapes Surgery in a Tertiary Referral Center: Surgical and Audiometric Outcomes.
CONCLUSIONS: Compared to the available literature, a slightly larger gain in air conduction and air-bone gap was achieved in our study. Air-bone gap closure to 10 dB or less was achieved less often in our study. PMID: 31161780 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - June 4, 2019 Category: ENT & OMF Authors: Blijleven EE, Wegner I, Tange RA, Thomeer HGXM Tags: Ann Otol Rhinol Laryngol Source Type: research

Auditory Cortical Plasticity and Reorganization in Rats With Single-Sided Deafness During Early Developmental Period.
CONCLUSION: Early onset of unilateral deafening leads to the alternation of contralateral dominance in the early period, replaced by faster and massive reorganization toward the ipsilateral cortex. But, gradual adaptation in the contralateral side was exclusively observed. Given the short critical period in the young SSD model, early intervention may be crucial for the development of binaural hearing if SSD occurs early in life. PMID: 31092025 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Park SK, Lee SY, Kim DH, Lee MY, Oh SH Tags: Ann Otol Rhinol Laryngol Source Type: research

Interaction Between Regulatory T Cells and Antibody-Producing B Cells for Immune Responses at the Upper Respiratory Mucosa Against Nontypeable Haemophilus influenzae: In Vitro Assay Model.
CONCLUSIONS: Tregs and Th cells did not affect OMP-specific immunoglobulin A production in this study. However, these cells may partially inhibit B-cell functions, such as T-cell activation. These inhibitory effects may be related to interleukin-10. PMID: 31092026 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Hirano T, Kadowaki Y, Matsunaga T, Yoshinaga K, Kawano T, Moriyama M, Suzuki M Tags: Ann Otol Rhinol Laryngol Source Type: research

Clinical Value of Measurement of Internal Auditory Canal in Pediatric Cochlear Implantation.
CONCLUSIONS: BCNC and IAC widths were narrower in children with b-SNHL than in normal-hearing children. Narrow BCNC and IAC width had a negative impact on post-CI outcomes. The proposed cutoff values for BCNC and IAC width were meaningful when predicting the auditory outcome after CI, especially considering both. PMID: 31092027 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Kim H, Kim DY, Ha EJ, Park HY Tags: Ann Otol Rhinol Laryngol Source Type: research

On the Legacy of Genetically Altered Mouse Models to Explore Vestibular Function: Distribution of Vestibular Hair Cell Phenotypes in the Otoferlin-Null Mouse.
CONCLUSION: These findings support the notion that modifications resulting in a specific component of vestibular hypofunction are not accompanied by widespread morphologic and cellular changes in the vestibular sensory epithelia. PMID: 31092028 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Prins TJ, Saldate JJ, Berke GS, Hoffman LF Tags: Ann Otol Rhinol Laryngol Source Type: research

Pathophysiologic Findings in the Human Endolymphatic Sac in Endolymphatic Hydrops: Functional and Molecular Evidence.
CONCLUSIONS: Although evidence is insufficient, studies using the human ES have mostly produced findings similar to those of animal studies. This review may provide a basis for planning further studies to investigate the pathophysiology of disorders with the finding of endolymphatic hydrops. PMID: 31092029 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Kim SH, Nam GS, Choi JY Tags: Ann Otol Rhinol Laryngol Source Type: research

External Auditory Canal Reconstruction and Mastoid Obliteration Using Modified Palva Flap in Canal Wall Down Mastoidectomy With Tympanoplasty.
CONCLUSIONS: The external auditory canal volume slightly increased, but the status of mastoid obliteration was well maintained 1 year after surgery. The modified Palva flap used in this study is an easy and effective method in external auditory canal reconstruction and mastoid obliteration. PMID: 31092030 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Kim JS, Lim IG, Oh JH, Kim BG, Chang KH Tags: Ann Otol Rhinol Laryngol Source Type: research

Role of Phosphorylcholine-Specific Immunoglobulin M in Acute Upper Respiratory Tract Infections.
CONCLUSIONS: PC-specific IgM is suggested to have protective and suppressive effects against the progression of infectious and inflammatory reactions. Higher levels of PC-specific IgM in women might be one of the reasons why the incidence and severity of acute epiglottitis and peritonsillar abscess are lower in women. PMID: 31092031 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Ohori J, Jimura T, Kurono Y Tags: Ann Otol Rhinol Laryngol Source Type: research

Otopetrin-2 Immunolocalization in the Human Macula Utricle.
CONCLUSIONS: Otopetrin-2 was localized in supporting cells in a similar fashion that otopetrin-1 previously reported in the mouse macula utricle. The differential expression of otopetrin-2 in the supporting cells of the human macula utricle suggest an important role in the vestibular sensory periphery homeostasis and otolith maintenance. PMID: 31092032 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Lopez PhD IA, Ishiyama Md G, Acuna MSc D, Ishiyama Md A Tags: Ann Otol Rhinol Laryngol Source Type: research

Preliminary Characterization of Extracellular Vesicles From Auditory HEI-OC1 Cells.
CONCLUSIONS: Altogether, the results suggest that EVs from HEI-OC1 cells could be advantageously used as biological nanocarriers for the delivery of specific molecules and pharmacological drugs into the inner ear. PMID: 31092033 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Kalinec PhD GM, Cohn BSc W, Whitelegge PhD JP, Faull PhD KF, Kalinec PhD F Tags: Ann Otol Rhinol Laryngol Source Type: research

Involvement of TNF- α and IFN-γ in Inflammation-Mediated Cochlear Injury.
CONCLUSIONS: Taken together, these findings suggest the involvement of IFN-γ in the sensitization of cochlear cells to TNF-α cytotoxicity, which would enable us to better understand the complex mechanisms underlying inflammation-mediated cochlear injury. PMID: 31092034 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Moon SK, Woo JI, Lim DJ Tags: Ann Otol Rhinol Laryngol Source Type: research

Pyridoxine Preferentially Induces Auditory Neuropathy Through Mitochondrial Dysfunction and Endoplasmic Reticulum Stress-Mediated Apoptosis.
CONCLUSION: Pyridoxine preferentially induced severe cell death on nerve fiber in primary OC explants and markedly increased apoptotic cell death via mitochondria-mediated ER stress in VOT-33 cells. PMID: 31092035 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Park C, Lim H, Moon SK, Park R Tags: Ann Otol Rhinol Laryngol Source Type: research

Cochlear Implant Surgery Through Round Window Approach Is Always Possible.
CONCLUSION: Cochlear implant surgery through RW is reliable, safe, and effective. The RW technique is reproducible via several surgical procedures in most CI cases. Identification and safe exposure of RW membrane is a prerequisite for successful electrode insertion in cochlear implant surgery. PMID: 31092036 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Bae SC, Shin YR, Chun YM Tags: Ann Otol Rhinol Laryngol Source Type: research

A Tribute to David J. Lim, MD: Researcher, Mentor, Organizer, and Friend.
PMID: 31092037 [PubMed] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Welling DB Tags: Ann Otol Rhinol Laryngol Source Type: research

Enhancement of Consonant Recognition in Bimodal and Normal Hearing Listeners.
CONCLUSIONS: Consonant recognition was improved with 3DDS in both groups. This observed benefit suggests 3DDS can be used as an auditory training tool for improved integration and for bimodal users who receive little or no benefit from their current bimodal hearing. PMID: 31092038 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Yoon YS, Riley B, Patel H, Frost A, Fillmore P, Gifford R, Hansen J Tags: Ann Otol Rhinol Laryngol Source Type: research

A 3-Dimensional Model of the Human Round Window Membrane.
CONCLUSIONS: The magnified 3-dimensional model clarified gross anatomy and characteristics of the RWM. It is good teaching material for small tissues, such as the RWM. PMID: 31092039 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Nomura Y, Tanaka T, Kobayashi H, Kimura Y, Soejima Y, Sawabe M Tags: Ann Otol Rhinol Laryngol Source Type: research

Sublingual Immunotherapy Attenuates Nasal Symptoms Upon Allergen Exposure in Murine Allergic Rhinitis Model via an Induction of IL-10 producing T cells in Submandibular Lymph Node.
CONCLUSION: These results demonstrate that sublingually introduced antigens can actually attenuate nasal symptoms in a murine allergic rhinitis model upon allergen exposures. Furthermore, our immunological data might indicate an important role of IL-10 producing T cells in SMLN to control nasal allergic reaction. PMID: 31092040 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Qu Md Y, Yamada PhD T, Aoi Md PhD N, Morikura Md PhD I, Fuchiwaki Md PhD T, Hotta Md Y, Prokopakis Md PhD E, Kawauchi Md DMSc H Tags: Ann Otol Rhinol Laryngol Source Type: research

A Tribute to Dr. David J. Lim: Remembering His Legacy.
PMID: 31092041 [PubMed] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Moon SK, Oh SH, Kawauchi H Tags: Ann Otol Rhinol Laryngol Source Type: research

Intratympanically Delivered Steroids Impact Thousands More Inner Ear Genes Than Systemic Delivery.
CONCLUSIONS: Thousands of inner ear genes were affected by steroids, and this number increased significantly if steroids were delivered intratympanically. Also, the impact of glucocorticoids on inner ear mineralocorticoid functions is more substantial than previously known. Thus, the application of therapeutic steroids for hearing loss needs to be reassessed in light of their more comprehensive impact on inner ear genes. Furthermore, simply ascribing the efficacy of steroids to immunosuppression no longer appears to be warranted. PMID: 31092042 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Trune DR, Shives KD, Hausman F, Kempton JB, MacArthur CJ, Choi D Tags: Ann Otol Rhinol Laryngol Source Type: research

Phantom Perception of Sound and the Abnormal Cortical Inhibition System: An Electroencephalography (EEG) Study.
CONCLUSION: Our results suggest that rTMS is a beneficial therapeutic treatment for chronic tinnitus patients and the dual-site treatment was the most effective in terms of both tinnitus complaint and quantitative indices. Thus, subjective reports and electrophysiological signatures may be complementary for the diagnosis/prognosis of tinnitus. PMID: 31092043 [PubMed - in process] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 18, 2019 Category: ENT & OMF Authors: Kyong JS, Noh TS, Park MK, Oh SH, Lee JH, Suh MW Tags: Ann Otol Rhinol Laryngol Source Type: research

Effects of OSA Surgery on Ophthalmological Microstructures.
CONCLUSION: The visual sensitivities on SAP, ML thickness on OCT, and oxygenation status on PSG significantly improved 6 months after upper airway surgery in patients with severe OSA. Upper airway surgery may ameliorate the microstructures of the retina in patients with severe OSA. PMID: 31091983 [PubMed - as supplied by publisher] (Source: The Annals of Otology, Rhinology, and Laryngology)
Source: The Annals of Otology, Rhinology, and Laryngology - May 15, 2019 Category: ENT & OMF Authors: Lin PW, Lin HC, Friedman M, Chang HW, Salapatas AM, Lin MC, Chin CH Tags: Ann Otol Rhinol Laryngol Source Type: research