The role of interindividual licking received and dopamine genotype on later ‐life licking provisioning in female rat offspring
ConclusionOur findings suggest that genetic variation influences the relationship between early ‐life maternal care received and the dopaminergic system of the maternal brain, which can indirectly influence later‐life maternal care provisioning. (Source: Brain and Behavior)
Source: Brain and Behavior - February 11, 2021 Category: Neurology Authors: Samantha C. Lauby, David G. Ashbrook, Hannan R. Malik, Diptendu Chatterjee, Pauline Pan, Alison S. Fleming, Patrick O. McGowan Tags: ORIGINAL RESEARCH Source Type: research

Cerebral areas affected by unilateral acupuncture on SP3 in healthy volunteers: An explorative resting ‐state fMRI study
ConclusionsThe most dominant cerebral areas affected by SP3 acupuncture were bilateral visual ‐related cortices (lingual gyrus, cuneus, and calcarine), along with the unilateral postcentral gyrus and superior parietal lobule. These findings may be potential explanations for the available clinical reports concerning the efficacy of SP3 acupuncture. Further clinical and experimental studies on SP3 acupuncture are required. (Source: Brain and Behavior)
Source: Brain and Behavior - February 9, 2021 Category: Neurology Authors: Feng Wang, Tiansong Yang, Xiaoling Li, Xiaohui Liu, Danna Cao, Delong Wang, Yan Yang, Chaoran Li, Yuanyuan Qu, Xu Zhao, Zhongren Sun, Tetsuya Asakawa Tags: ORIGINAL RESEARCH Source Type: research

Implementation of high ‐cadence cycling for Parkinson’s disease in the community setting: A pragmatic feasibility study
ConclusionBarriers to implementation of nonpharmacologic interventions such as exercise protocols limit reach and availability of these interventions to patients. Pilot studies are needed to inform and direct further implementation efforts. Our pilot study suggests the PFP cycling intervention should be modified prior to attempts at widespread implementation. Modifications made by gyms in this study suggest adaptations to the protocol that may increase fidelity and effectiveness. (Source: Brain and Behavior)
Source: Brain and Behavior - February 9, 2021 Category: Neurology Authors: Kathleen E. McKee, Remy K. Johnson, James Chan, Anne ‐Marie Wills Tags: ORIGINAL RESEARCH Source Type: research

Effects of short ‐term cognitive‐coping therapy on resting‐state brain function in obsessive‐compulsive disorder
This study investigated the effects of CCT on OCD and the resting ‐state brain function were investigated in 59 OCD patients underwent CCT, pharmacotherapy plus CCT (pCCT), or pharmacotherapy. The effectiveness of CCT for OCD was related to the alteration of resting‐state brain function ‐ the brain plasticity. AbstractBackgroundObsessive ‐compulsive disorder (OCD) tends to be treatment refractory. Recently, cognitive‐coping therapy (CCT) for OCD is reported to be an efficacious psychotherapy. However, the underlying neurophysiological mechanism remains unknown. Here, the effects of CCT on OCD and the resting‐st...
Source: Brain and Behavior - February 9, 2021 Category: Neurology Authors: Jian ‐Dong Ma, Chang‐Hong Wang, Ping Huang, Xunan Wang, Li‐Jing Shi, Heng‐Fen Li, De‐En Sang, Shao‐Jie Kou, Zhi‐Rong Li, Hong‐Zeng Zhao, Hong‐Kai Lian, Xian‐Zhang Hu Tags: ORIGINAL RESEARCH Source Type: research

Aberrant central plasticity underlying synchronous sensory phenomena in brachial plexus injuries after contralateral cervical seventh nerve transfer
The tactile sensory of the injured hand was dominated by its ipsilateral SI in long ‐term observation, and its representative area overlapped largely with representative area of the intact hands, which was the key mechanism for synchronous sensory phenomenon in patients with TBPI after contralateral C7 transfer. AbstractBackgroundsContralateral cervical seventh (C7) nerve transfer aids motor and sensory recovery in total brachial plexus avulsion injuries (TBPI), but synchronous sensation often persists postoperatively. The mechanism underlying synchronous sensory phenomena remain largely unknown.ObjectiveTo investigate t...
Source: Brain and Behavior - February 6, 2021 Category: Neurology Authors: Zeyu Cai, Gaowei Lei, Jie Li, Yundong Shen, Yudong Gu, Juntao Feng, Wendong Xu Tags: ORIGINAL RESEARCH Source Type: research

Seizures as onset symptoms and rapid course in preschool children with subacute sclerosing panencephalitis
ConclusionsIn younger children, the characteristic features of SSPE may be seizures and gait instability as onset manifestations, atypical periodic complexes on EEG, and rapid worsening of neurological conditions. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2021 Category: Neurology Authors: Shuang Liao, Min Zhong, Nan Zou, Tingsong Li, Li Jiang Tags: ORIGINAL RESEARCH Source Type: research

Inhibition of emotions in healthy aging: age ‐related differences in brain network connectivity
ConclusionIn this first fMRI study of emotional Stroop interference in older and younger adults, we found that the emotional interference effect was unchanged in healthy aging and replicated the finding from non ‐emotional task studies that older adults have greater between‐network and less within‐network connectivity compared to younger adults. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2021 Category: Neurology Authors: Ina S. Almdahl, Liva J. Martinussen, Ingrid Agartz, Kenneth Hugdahl, Maria S. Korsnes Tags: ORIGINAL RESEARCH Source Type: research

Separating scale ‐free and oscillatory components of neural activity in schizophrenia
ConclusionOur results imply strong functional significance of scale ‐free neural activity in SZ and suggest that abnormalities in PSD may emerge from alterations of the fractal and not only the oscillatory components of neural activity. (Source: Brain and Behavior)
Source: Brain and Behavior - February 4, 2021 Category: Neurology Authors: Frigyes Samuel Racz, Kinga Farkas, Orestis Stylianou, Zalan Kaposzta, Akos Czoch, Peter Mukli, Gabor Csukly, Andras Eke Tags: ORIGINAL RESEARCH Source Type: research

Open ‐label study with the monoamine stabilizer (‐)‐OSU6162 in myalgic encephalomyelitis/chronic fatigue syndrome
Conclusions( ‐)‐OSU6162 is well tolerated in ME/CFS patients and shows promise as a novel treatment to mitigate fatigue and improve mood and health‐related quality of life in ME/CFS. Obviously, the present results need to be confirmed in future placebo‐controlled double‐blind trials. (Source: Brain and Behavior)
Source: Brain and Behavior - February 4, 2021 Category: Neurology Authors: Sara Haghighi, Sara Forsmark, Olof Zachrisson, Arvid Carlsson, Marie K. L. Nilsson, Maria L. Carlsson, Robert C. Schuit, Carl ‐Gerhard Gottfries Tags: ORIGINAL RESEARCH Source Type: research

Late gestational exposure to dexamethasone and fetal programming of abnormal behavior in Wistar Kyoto rats
ConclusionOur results indicate adult offspring exposed to dexamethasone in ‐utero have a tendency toward passive stress‐coping strategies and an inhibition of anxiety on behavioral tasks. Methyltransferase activity, synaptic activity, and cellular processes were disrupted in the prefrontal cortices of these animals. Specifically, genes involved in emotional response pa thways were overexpressed, supporting the link between the behavioral and genetic profiles. Combined, we determine that dexamethasone offspring have adaptive predispositions when faced with novel situations, with increased immobility in the swim task and...
Source: Brain and Behavior - February 2, 2021 Category: Neurology Authors: Christine Lalonde, Julie Grandbois, Sandhya Khurana, Alyssa Murray, Sujeenthar Tharmalingam, T. C. Tai Tags: ORIGINAL RESEARCH Source Type: research

Gender differences in subliminal affective face priming: A high ‐density ERP study
ConclusionsOur ERP results suggest the existence of a gender difference in target ‐face processing preceded by subliminally presented face stimuli in the right occipito‐temporal region. (Source: Brain and Behavior)
Source: Brain and Behavior - February 2, 2021 Category: Neurology Authors: Mutsuhide Tanaka, Emi Yamada, Toshihiko Maekawa, Katsuya Ogata, Naomi Takamiya, Hisato Nakazono, Shozo Tobimatsu Tags: ORIGINAL RESEARCH Source Type: research

REVERSE phenotyping —Can the phenotype following constitutive Tph2 gene inactivation in mice be transferred to children and adolescents with and without adhd?
ConclusionAt the example of trait aggression, our results support the assumption that theTph2 null mutant mouse reflects theTPH2G ‐703T‐dependent phenotype in humans. Additionally, we conclude that “reverse phenotyping” is a promising method to validate experimental models and human findings for refined analysis of disease mechanisms. (Source: Brain and Behavior)
Source: Brain and Behavior - February 1, 2021 Category: Neurology Authors: Atae Akhrif, Arunima Roy, Katharina Peters, Klaus ‐Peter Lesch, Marcel Romanos, Angelika Schmitt‐Böhrer, Susanne Neufang Tags: ORIGINAL RESEARCH Source Type: research

A timed Phalen ’s test predicts abnormal electrophysiology in carpal tunnel syndrome
DiscussionA positive TPT at  ≤ 10 s can be useful in predicting NCS abnormalities in patients with CTS. (Source: Brain and Behavior)
Source: Brain and Behavior - January 29, 2021 Category: Neurology Authors: Mohammed H. Alanazy, Hana Albulaihe, Ziad Alhumayyd, Anas M. Albarrak, Ahmad R. Abuzinadah Tags: ORIGINAL RESEARCH Source Type: research

Patterns of cortical grey matter thickness reduction in multiple sclerosis
ConclusionCortical thickness reduction patterns in MS are mostly characterized by the degree of temporal lobe cortical atrophy, which may start in the relapsing –remitting phase. Among the temporal lobe cortices, the neurodegenerative change may accelerate in the temporal pole in the progressive phase. (Source: Brain and Behavior)
Source: Brain and Behavior - January 28, 2021 Category: Neurology Authors: Juichi Fujimori, Kazuo Fujihara, Mike Wattjes, Ichiro Nakashima Tags: ORIGINAL RESEARCH Source Type: research

Health ‐related quality of life among Ethiopian pregnant women during COVID‐19 pandemic
This study was aimed to explore the quality of life among pregnant women during corona virus disease 2019 (COVID ‐19). Statistics such as Independent samplest‐test, One‐way analysis of variance (ANOVA), Pearson's correlation and standard multiple regression were employed. The mean age of the participants was 31.3 ± 7.7 and perceived social support has positive effect on quality of life among pregnant women. AbstractObjectiveTo explore the quality of life and its association with perceived social support and pandemic fear among pregnant women.MethodsCross ‐sectional study was conducted among 384 pregnant...
Source: Brain and Behavior - January 28, 2021 Category: Neurology Authors: Aman Dule, Mohammedamin Hajure, Mustefa Mohammedhussein, Zakir Abdu Tags: ORIGINAL RESEARCH Source Type: research

Study of rapid reorganization of visual neurofunctions with the resting ‐state functional MRI in pituitary adenoma patients with vision improvement after transsphenoidal surgery
ConclusionsThe results show most subareas within the visual cortex exhibit decreased functional connectivity. The functional changes in subareas within default mode network (DMN), action observation network (AON) and the multisensory system in PAs propose that vision improvement may lead to function remodeling in higher ‐order cortex. (Source: Brain and Behavior)
Source: Brain and Behavior - January 27, 2021 Category: Neurology Authors: Fuyu Wang, Peng Wang, Yuyang Liu, Tao Zhou, Xianghui Meng, Jinli Jiang Tags: ORIGINAL RESEARCH Source Type: research

Neurofeedback training improves anxiety trait and depressive symptom in GAD
Neurofeedback training of alpha activity over the parietal lobe is effective in GAD patients. Especially on the improvement of GAD patients ’ anxiety trait and depressive symptoms. AbstractObjectiveTo investigate the effectiveness of alpha activity neurofeedback training over the parietal lobe in GAD patients.MethodsTwenty ‐six female patients who had been diagnosed as GAD according to the Diagnostic and Statistical Manual of Mental Disorders (5th edition, DSM‐V) criteria were included in this study. Patients were randomized into two groups: the left parietal lobe training group (LPL group,n = 13) and t...
Source: Brain and Behavior - January 27, 2021 Category: Neurology Authors: Yue Hou, Shuqin Zhang, Ning Li, Zhaoyang Huang, Li Wang, Yuping Wang Tags: ORIGINAL RESEARCH Source Type: research

Actor or recipient role matters: Neural correlates of self ‐serving bias
ConclusionThe results suggest that people prefer making heuristic SSB attributions, and more cognitive resources are needed when they make NONSSB attributions. The activity of the dmPFC may be associated with inhibiting the heuristic SSB, especially when they play the actor role at interpersonal events. (Source: Brain and Behavior)
Source: Brain and Behavior - January 26, 2021 Category: Neurology Authors: Xiaoyan Wang, Li Zheng, Lin Li, Peng Sun, Xiuyan Guo Tags: ORIGINAL RESEARCH Source Type: research

Hungarian validation of the Buss –Perry Aggression Questionnaire—Is the short form more adequate?
ConclusionBoth the BPAQ and the BPAQ ‐SF, also the BAQ provide acceptable model fitting on a Hungarian sample of university students. While most of BPAQ items provided adequate loadings on their hypothesized factors, two items (21 and 27) did not. We argue this is the result of conceptual inaccuracy of the original items. (Source: Brain and Behavior)
Source: Brain and Behavior - January 25, 2021 Category: Neurology Authors: Szabolcs Zimonyi, Krisztian Kasos, Zsuzsa Halmai, Luca Csirmaz, Helga Stadler, S ándor Rózsa, Anna Szekely, Eszter Kotyuk Tags: ORIGINAL RESEARCH Source Type: research

Kv1.1 deficiency alters repetitive and social behaviors in mice and rescues autistic ‐like behaviors due to Scn2a haploinsufficiency
ConclusionsTaken together, these findings suggest that Kv1.1 subunits are important in pathways and neural networks underlying ASD and thatKcna1 may be a therapeutic target for treatment ofScn2a‐associated ASD. (Source: Brain and Behavior)
Source: Brain and Behavior - January 23, 2021 Category: Neurology Authors: Jagadeeswaran Indumathy, April Pruitt, Nicole M. Gautier, Kaitlin Crane, Edward Glasscock Tags: ORIGINAL RESEARCH Source Type: research

Generalized neurocognitive impairment in individuals at ultra ‐high risk for psychosis: The possible key role of slowed processing speed
ConclusionSlowed processing speed may underlie generalized neurocognitive impairment in UHR individuals and represent a potential intervention target. (Source: Brain and Behavior)
Source: Brain and Behavior - January 23, 2021 Category: Neurology Authors: Lasse Randers, Jens Richardt M øllegaard Jepsen, Birgitte Fagerlund, Dorte Nordholm, Kristine Krakauer, Carsten Hjorthøj, Birte Glenthøj, Merete Nordentoft Tags: ORIGINAL RESEARCH Source Type: research

Brain region volumes and their relationship with disability progression and cognitive function in primary progressive multiple sclerosis
ConclusionsWhite and gray matter volumes of specific brain regions could predict disability progression and cognitive performance of PPMS patients after one year. (Source: Brain and Behavior)
Source: Brain and Behavior - January 23, 2021 Category: Neurology Authors: Francisco Carlos P érez‐Miralles, Daniel Prefasi, Antonio García‐Merino, José Ramón Ara, Guillermo Izquierdo, Virginia Meca‐Lallana, Francisco Gascón‐Giménez, María Luisa Martínez‐Ginés, Lluis Ramió‐Torrentà, Lucienne Costa Tags: ORIGINAL RESEARCH Source Type: research

Keeping the inner voice inside the head, a pilot fMRI study
ConclusionsThese pilot data suggest that internal space localization of the inner voice depends on the same neural resources as that for external space localization of external voices —the “where” auditory pathway. We discuss the implications of these findings on the possible mechanisms of abnormal experiences of the inner voice as is the case in verbal hallucinations. (Source: Brain and Behavior)
Source: Brain and Behavior - January 22, 2021 Category: Neurology Authors: Massoud Stephane, Mario Dzemidzic, Gihyun Yoon Tags: ORIGINAL RESEARCH Source Type: research

Issue Information
Brain and Behavior, Volume 11, Issue 1, January 2021. (Source: Brain and Behavior)
Source: Brain and Behavior - January 22, 2021 Category: Neurology Tags: ISSUE INFORMATION Source Type: research

The effects of voluntary complex and regular wheel running exercises on the levels of 8 ‐oxoguanine DNA glycosylase, semaphorin 3B, H2O2, and apoptosis in the hippocampus of diabetic rats
ConclusionThe increased levels of Sema3B, H2O2, and apoptosis within the hippocampus associated with diabetes could be noticeably restored by both types of voluntary wheel running protocols. (Source: Brain and Behavior)
Source: Brain and Behavior - January 20, 2021 Category: Neurology Authors: Mohammad Fazelzadeh, Mohammad Esmaeil Afzalpour, Ziya Fallah Mohammadi, Hossein Falah Mohammadi Tags: ORIGINAL RESEARCH Source Type: research

Olfactory function and viral recovery in COVID ‐19
We conducted a prospective cross ‐sectional study in consecutive hospitalized patients with confirmed SARS‐CoV‐2 infection to assess smell impairment and determine whether olfactory deficit could be a marker of active infection. Patients were asked about subjective olfactory and taste disorders and underwent an objective asse ssment of olfactory function with the Smell Identification subtest of the Sniffin’ Sticks Test. Besides confirming that olfactory deficits are present in about half of the patients, study main finding showed that none of the patients with anosmia and the 5.8% of the patients with hyposmia ...
Source: Brain and Behavior - January 19, 2021 Category: Neurology Authors: Marco Mazzoli, Maria Angela Molinari, Manuela Tondelli, Giada Giovannini, Riccardo Ricceri, Ludovico Ciolli, Livio Picchetto, Stefano Meletti Tags: ORIGINAL RESEARCH Source Type: research

Functional heterogeneity in the left lateral posterior parietal cortex during visual and haptic crossmodal dot ‐surface matching
ConclusionTaken together,  the findings suggest that functional heterogeneity of the left LPPC during visuo‐haptic crossmodal dot‐surface retrieval processing reflects that the left LPPC does not simply contribute to retrieval of past information; rather, each subregion has a specific functional role in resolving diffe rent task requirements. (Source: Brain and Behavior)
Source: Brain and Behavior - January 19, 2021 Category: Neurology Authors: Jiajia Yang, Yinghua Yu, Hiroaki Shigemasu, Hiroshi Kadota, Kiyoshi Nakahara, Takanori Kochiyama, Yoshimichi Ejima, Jinglong Wu Tags: ORIGINAL RESEARCH Source Type: research

Patient use of a self ‐monitoring app during eating disorder treatment: Naturalistic longitudinal cohort study
ConclusionFuture research on long ‐term app engagement should investigate associations between patients’ app use and changes in their eating disorder symptom severity over time. (Source: Brain and Behavior)
Source: Brain and Behavior - January 18, 2021 Category: Neurology Authors: Pil Lindgreen, Kirsten Lomborg, Loa Clausen Tags: ORIGINAL RESEARCH Source Type: research

A network structure of manic symptoms
ConclusionsThe investigation of manic symptoms with network analysis allows for identifying important symptoms that are better connected to other symptoms at a given moment and over time. The connectivity of the manic symptoms evolves over time. Central symptoms could be considered as targets for clinical intervention when treating severe mania. (Source: Brain and Behavior)
Source: Brain and Behavior - January 16, 2021 Category: Neurology Authors: Giovanni Briganti, Charles Kornreich, Paul Linkowski Tags: ORIGINAL RESEARCH Source Type: research

Relation of retinal and hippocampal thickness in patients with amnestic mild cognitive impairment and healthy controls
ConclusionsDifferent temporal trajectories of neurodegeneration may disrupt transregional brain structure associations in patients with amnestic mild cognitive impairment. (Source: Brain and Behavior)
Source: Brain and Behavior - January 15, 2021 Category: Neurology Authors: Markus Donix, Dierk Wittig, Wiebke Hermann, Robert Haussmann, Maren Dittmer, Franziska Bienert, Maria Buthut, Liane Jacobi, Annett Werner, Jennifer Linn, Tjalf Ziemssen, Moritz D. Brandt Tags: ORIGINAL RESEARCH Source Type: research

Components determining the slowness of information processing in parkinson ’s disease
ConclusionsThe results revealed that slowness of information processing in PD was mainly associated with an impaired processing speed of the motor and perceptual ‐alertness components analyzed. The results may help designing new neurorehabilitation strategies, focusing on the improvement of perceptual and alertness mechanisms. (Source: Brain and Behavior)
Source: Brain and Behavior - January 15, 2021 Category: Neurology Authors: Aida Arroyo, Jos é A. Periáñez, Marcos Ríos‐Lago, Genny Lubrini, Jorge Andreo, Julián Benito‐León, Elan D. Louis, Juan Pablo Romero Tags: ORIGINAL RESEARCH Source Type: research

Callosal abnormalities, altered cortisol levels, and neurocognitive deficits associated with early maltreatment among adolescents: A voxel ‐based diffusion‐tensor imaging study
In our study, objective measures of childhood maltreatment were associated with abnormal white matter microstructure in posterior regions of the CC (splenium), and correlated with specific neurocognitive impairments and abnormal cortisol levels. AbstractIntroductionNeuroimaging studies have shown callosal abnormalities among maltreated subjects, but little is known about the functional and neurobiological correlates of these supposed developmental alterations. The aim of this study was to investigate childhood maltreatment (CM), neurocognitive functioning, cortisol levels, and corpus callosum (CC) integrity among adolescen...
Source: Brain and Behavior - January 15, 2021 Category: Neurology Authors: Paulo Jannuzzi Cunha, Fabio L.S. Duran, Paula Approbato Oliveira, Tiffany M. Chaim ‐Avancini, Ana Luiza V. Milioni, Mariella Ometto, Paula Squarzoni, Pedro P. Santos, Sheila C. Caetano, Geraldo F. Busatto, Sandra Scivoletto Tags: ORIGINAL RESEARCH Source Type: research

Maternal depression and childhood injury risk: A population ‐based cohort study in Denmark
ConclusionsMaternal depression was associated with higher injury risk in the offspring, particularly in early childhood. The association persisted in children of mothers with relapse depression. Our results suggest that children of mothers with depression are vulnerable several years after depression onset and treatment cessation. (Source: Brain and Behavior)
Source: Brain and Behavior - January 15, 2021 Category: Neurology Authors: Bente Kj ær Lyngsøe, Trine Munk‐Olsen, Claus Høstrup Vestergaard, Dorte Rytter, Kaj Sparle Christensen, Bodil Hammer Bech Tags: ORIGINAL RESEARCH Source Type: research

Mapping the orbitofrontal cortex using temporal fluctuations in cerebral blood flow
ConclusionTo our knowledge, this constitutes the first in vivo cortical parcellation based on perfusion fluctuations. Our approach confirms functional OFC subdivisions predicted from anatomy using a less susceptibility ‐sensitive method than the conventional approach. (Source: Brain and Behavior)
Source: Brain and Behavior - January 13, 2021 Category: Neurology Authors: Kalen J. Petersen, Manus J. Donahue, Daniel O. Claassen Tags: ORIGINAL RESEARCH Source Type: research

Association between attention deficit hyperactivity disorder and aggression subscales in adolescents
ConclusionsOur results demonstrated that ADHD proneness was significantly associated with aggression propensity. In particular, anger and hostility were more closely associated with ADHD proneness than were other aggression subdomains. (Source: Brain and Behavior)
Source: Brain and Behavior - January 13, 2021 Category: Neurology Authors: Hee Jeong Yoo, Ji Min Han, Kitai Kim, Gonjin Song, Jeong Yee, Jee Eun Chung, Kyung Eun Lee, Hye Sun Gwak Tags: ORIGINAL RESEARCH Source Type: research

Long ‐term misdiagnosis and neurologic outcomes of thallium poisoning: A case report and literature review
DiscussionThallium intoxication may have been initially identified if neurologic symptoms had occurred concurrently with gastrointestinal and cutaneous symptoms. Neurologic damage represented the main sequelae of thallium poisoning in our present case report. (Source: Brain and Behavior)
Source: Brain and Behavior - January 13, 2021 Category: Neurology Authors: Hailing Liu, Geng Liao Tags: ORIGINAL RESEARCH Source Type: research

Cortical morphometric changes associated with completeness, level, and duration of spinal cord injury in humans: A case –control study
ConclusionsThe study provided imaging evidence for identifying cerebral structural abnormalities in SCI patients and significant differences in complete/incomplete and paraplegia/tetraplegia subgroups. These results suggested brain structural changes occur after SCI and these changes may depend on the injury completeness, level, and duration. (Source: Brain and Behavior)
Source: Brain and Behavior - January 13, 2021 Category: Neurology Authors: Yun Guo, Feng Gao, Hua Guo, Weiyong Yu, Zhenbo Chen, Mingliang Yang, Degang Yang, Liangjie Du, Jianjun Li Tags: ORIGINAL RESEARCH Source Type: research

Tract ‐specific analysis and neurocognitive functioning in sickle cell patients without history of overt stroke
ConclusionDecreased DTI ‐derived metrics were observed on six tracts in chronically anemic patients, regardless of anemia subtype, while two tracks with decreased measures were unique to SCD patients. Patients with WMHs had more significant FA abnormalities. Decreased FA values in the CC significantly correlated with all nine neurocognitive tests, suggesting a critical importance for CC in core neurocognitive processes. (Source: Brain and Behavior)
Source: Brain and Behavior - January 12, 2021 Category: Neurology Authors: Yaqiong Chai, Chaoran Ji, Julie Coloigner, Soyoung Choi, Melissa Balderrama, Chau Vu, Benita Tamrazi, Thomas Coates, John C. Wood, Sharon H. O'Neil, Natasha Lepore Tags: ORIGINAL RESEARCH Source Type: research

Phenotypic characterization of frontal cortex microglia in a rat model of post ‐traumatic stress disorder
ConclusionPsychological trauma impacts the immunological phenotype of microglia of the frontal cortex. Consequently, future studies should further evaluate the mechanistic role of microglia in PTSD pathology. (Source: Brain and Behavior)
Source: Brain and Behavior - January 12, 2021 Category: Neurology Authors: Thomas S. Cotrone, Charina B. Hocog, Joseph T. Ramsey, Marcus A. Sanchez, Heather M. Sullivan, Angus G. Scrimgeour Tags: ORIGINAL RESEARCH Source Type: research

Central nervous system manifestations in COVID ‐19 patients: A systematic review and meta‐analysis
ConclusionsThe growing number of studies has reported COVID ‐19, CNS presentations as remarkable manifestations that happen. Hence, understanding the CNS characteristics of COVID‐19 can help us for better diagnosis and ultimately prevention of worse outcomes. (Source: Brain and Behavior)
Source: Brain and Behavior - January 9, 2021 Category: Neurology Authors: Shahrzad Nazari, Amirhossein Azari Jafari, Seyyedmohammadsadeq Mirmoeeni, Saeid Sadeghian, Mohammad Eghbal Heidari, Siavash Sadeghian, Farhad Assarzadegan, Seyed Mahmoud Puormand, Hamid Ebadi, Davood Fathi, Sahar Dalvand Tags: REVIEW Source Type: research

Lifetime psychiatric hospital diagnoses among 8,412 Danish men registered in an outpatient alcohol clinic
ConclusionAmong men with a lifetime psychiatric hospital diagnosis, AUD is rarely diagnosed without psychiatric comorbidity at first ‐time admissions to psychiatric hospital departments. (Source: Brain and Behavior)
Source: Brain and Behavior - January 9, 2021 Category: Neurology Authors: Lea A. N. Christoffersen, Erik L. Mortensen, Merete Osler, Holger J. S ørensen, Ulrik Becker, Trine Flensborg‐Madsen Tags: ORIGINAL RESEARCH Source Type: research

Social –emotional functioning in young people with symptoms of eating disorders: A gender inclusive analogue study
ConclusionThese data suggest that the social –emotional difficulties, particularly with emotion recognition and regulation, present in clinical samples are also evident in young people of all genders with significant disordered eating. Future work could aim to recruit an even more gender‐diverse community sample to further elucidate social –emotional functioning in individuals in the community with significant disordered eating. (Source: Brain and Behavior)
Source: Brain and Behavior - January 9, 2021 Category: Neurology Authors: Ashley Boscoe, Rebecca Stanbury, Amy Harrison Tags: ORIGINAL RESEARCH Source Type: research

Hemodynamic and behavioral changes in older adults during cognitively demanding dual tasks
This study aims to examine how older adults mitigate executive demands while walking during cognit ively demanding tasks.MethodsTwenty healthy older adults (M  = 71.8  years,SD = 6.4) performed simple reaction time (SRT), go/no‐go (GNG), n‐back (NBK), and double number sequence (DNS) cognitive tasks of increasing difficulty while walking (i.e., dual task). Functional near infra‐red spectroscopy (fNIRS) was used to measure the hemodynamic response (i.e., oxy‐ [Hb O2] and deoxyhemoglobin [HbR]) changes in the prefrontal cortex (PFC) during dual and single tasks (i.e., walking alone). In addit...
Source: Brain and Behavior - January 8, 2021 Category: Neurology Authors: Talia Salzman, Diana Tob ón Vallejo, Nadia Polskaia, Lucas Michaud, Gabrielle St‐Amant, Yves Lajoie, Sarah Fraser Tags: ORIGINAL RESEARCH Source Type: research

Olfactory impairment in Wilson ’s disease
ConclusionsPatients with WD may have stable, selective olfactory impairments. This selective pattern may be a useful tool for disease diagnosis and prediction. (Source: Brain and Behavior)
Source: Brain and Behavior - January 7, 2021 Category: Neurology Authors: Lei Chen, Xin Wang, Richard L. Doty, Shanshan Cao, Junxiu Yang, Feng Sun, Xiaoyan Yan Tags: ORIGINAL RESEARCH Source Type: research

Reduced hippocampal volumes and memory deficits in adolescents with single ventricle heart disease
Right hippocampal volume was significantly reduced in adolescents with SVHD compared to controls, localized in several sites (CA1, CA4, subiculum, and dentate gyrus), which are associated with memory deficits and trended toward significance in anxiety and mood. AbstractIntroductionAdolescents with single ventricle congenital heart disease (SVHD) show functional deficits, particularly in memory and mood regulation. Hippocampi are key brain structures that regulate mood and memory; however, their tissue integrity in SVHD is unclear. Our study aim is to evaluate hippocampal volumes and their associations with memory, anxiety,...
Source: Brain and Behavior - January 7, 2021 Category: Neurology Authors: Nancy A. Pike, Bhaswati Roy, Stefanie Moye, Cristina Cabrera ‐Mino, Mary A. Woo, Nancy J. Halnon, Alan B. Lewis, Rajesh Kumar Tags: ORIGINAL RESEARCH Source Type: research

Psychological impact of COVID ‐19 pandemic on healthcare workers in China Xi’an central hospital
ConclusionsThe COVID ‐19 pandemic has increased psychological stress among healthcare workers with 10 years or more work experiences and who recently experienced a career position change. (Source: Brain and Behavior)
Source: Brain and Behavior - January 6, 2021 Category: Neurology Authors: Nan Wang, Yongqin Li, Qiaoxia Wang, Caihong Lei, Yuanyuan Liu, Shanshan Zhu Tags: ORIGINAL RESEARCH Source Type: research

α‐tACS over the somatosensory cortex enhances tactile spatial discrimination in healthy subjects with low alpha activity
ConclusionsThis study showed that 10 ‐Hz tACS can improve tactile orientation discrimination in subjects with low alpha activity. Alpha‐frequency tACS may help identify the contributions of these oscillations to other neurophysiological and pathological processes. (Source: Brain and Behavior)
Source: Brain and Behavior - January 6, 2021 Category: Neurology Authors: Kei Saito, Naofumi Otsuru, Hirotake Yokota, Yasuto Inukai, Shota Miyaguchi, Sho Kojima, Hideaki Onishi Tags: ORIGINAL RESEARCH Source Type: research

Zonisamide effects on sleep problems and depressive symptoms in Parkinson ’s disease
ConclusionWe showed the beneficial effects of ZNS on motor symptoms and sleep problems in levodopa ‐treated PD patients with motor fluctuation. ZNS may be more effective for several nonmotor symptoms in PD patients with tremor compared with those without tremor. (Source: Brain and Behavior)
Source: Brain and Behavior - January 5, 2021 Category: Neurology Authors: Keisuke Suzuki, Hiroaki Fujita, Takeo Matsubara, Yasuo Haruyama, Taro Kadowaki, Kei Funakoshi, Yuji Watanabe, Koichi Hirata Tags: ORIGINAL RESEARCH Source Type: research

Subjective versus objective symptom intensities ratings in cervical dystonia and hemifacial spasm across a botulinum neurotoxin cycle
ConclusionThe emotional situation should be assessed regularly in patients undergoing BoNT therapy. (Source: Brain and Behavior)
Source: Brain and Behavior - January 5, 2021 Category: Neurology Authors: Julia W öllner, David Weise, Bernd Leplow Tags: ORIGINAL RESEARCH Source Type: research

How well do clinical and demographic characteristics predict Patient Health Questionnaire ‐9 scores among patients with treatment‐resistant major depressive disorder in a real‐world setting?
ConclusionsWhile there is room for improvement in its accuracy, the use of a machine learning tool that predicts depression symptom severity of patients with TRD can potentially have wide population ‐level applications. Healthcare systems and payers can build upon this groundwork and use the variables identified and the predictive modeling approach to create an algorithm specific to their population. (Source: Brain and Behavior)
Source: Brain and Behavior - January 5, 2021 Category: Neurology Authors: Jennifer Voelker, Kruti Joshi, Ella Daly, Eros Papademetriou, David Rotter, John J. Sheehan, Harsh Kuvadia, Xing Liu, Anandaroop Dasgupta, Ravi Potluri Tags: ORIGINAL RESEARCH Source Type: research