Plasma SOMAmer proteomics of postoperative delirium
ConclusionIn older patients who have undergone major surgery, plasma SOMAmer proteomics may provide a relatively non-invasive benchmark to identify biomarkers associated with postoperative delirium. (Source: Brain and Behavior)
Source: Brain and Behavior - February 13, 2024 Category: Neurology Authors: Jacqueline M. Leung,
Julio C. Rojas,
Laura P. Sands,
Brandon Chan,
Binita Rajbanshi,
Zhiyuan Du,
Pang Du,
the Perioperative Medicine Research group Tags: ORIGINAL ARTICLE Source Type: research
Pregnancy ‐related knowledge in women with epilepsy in childbearing age: A pilot questionnaire survey from China
ConclusionIn our study, the understanding of pregnancy-related knowledge did not differ from WWE and their caregivers, both are far from satisfactory in certain areas. It is urgent for WWE and their caregivers to improve their pregnancy-related knowledge of epilepsy. As their primary access is from knowledgeable health care professionals like neurologists, well-trained neurologists in epilepsy management during pregnancy are in need. (Source: Brain and Behavior)
Source: Brain and Behavior - February 11, 2024 Category: Neurology Authors: Qiwei Li,
Yina Cao,
Jingxin Zhang,
Yanlu Fu,
Beibei Shen,
Shuang Wang,
Jiajia Fang Tags: ORIGINAL ARTICLE Source Type: research
Causal relationship between inflammatory factors and cerebral small vessel disease: Univariate, multivariate, and summary ‐data‐based mendelian randomization analysis
ConclusionAccording to MR and SMR analysis, higher levels of TRAIL increased the risk of SVS by upregulating gene expression of KNG1 in brain cortex tissues. In addition, protective effects of E-selectin and IL-3a levels on WMPVS were regulated by increased DNA methylation of gene ABO in blood tissue. (Source: Brain and Behavior)
Source: Brain and Behavior - February 10, 2024 Category: Neurology Authors: Tian ‐Ci Qiao,
Hao‐Yu Tian,
Shi‐Zhe Shan,
Li‐Li Shan,
Zheng‐Yu Peng,
Jia Ke,
Meng‐Ting Li,
Yang Wu,
Yan Han Tags: ORIGINAL ARTICLE Source Type: research
Correlation analysis between cerebral microangiopathy and autonomic nervous dysfunction
ConclusionWe demonstrates that age, history of leukoaraiosis, cognitive function assessment, blood uric acid, Hcy level, 24-h SBPSD, dSBPSD, nSBPSD, blood pressure, SDNN, RMSSD, HF, LF, and coronary heart disease were highly associated with cerebral microangiopathy with autonomic dysfunction. Furthermore, the influencing factors of cerebral microangiopathy with autonomic dysfunction are age, history of leukoaraiosis, ASP score, SSR, blood pressure variability, and HRV. (Source: Brain and Behavior)
Source: Brain and Behavior - February 10, 2024 Category: Neurology Authors: Na Liu,
Hongmin Wang,
Bing Han,
Wenyuan Wang,
Moqing Zhou,
Lin Yang,
Yanyong Wang Tags: ORIGINAL ARTICLE Source Type: research
UK Medical Cannabis Registry: Assessment of clinical outcomes in patients with insomnia
ConclusionPatients with insomnia experienced an improvement in sleep quality following the initiation of CBMPs in this medium-term analysis. Fewer than 15% of participants reported one or more adverse events. However, due to the limitations of the study design, further investigation is required before definitive conclusions can be drawn on the efficacy of CBMPs in treating insomnia. (Source: Brain and Behavior)
Source: Brain and Behavior - February 10, 2024 Category: Neurology Authors: Kavyesh Vivek,
Zekiye Karagozlu,
Simon Erridge,
Carl Holvey,
Ross Coomber,
James J. Rucker,
Mark W. Weatherall,
Mikael H Sodergren Tags: ORIGINAL ARTICLE Source Type: research
Attitudes and perceptions of Irish health care professionals regarding functional neurological disorder: A national survey
ConclusionThis study indicates that there is a significant need to improve FND education among HCPs in Ireland, in addition to developing appropriately resourced, integrated, multidisciplinary care pathways for the FND patient group. (Source: Brain and Behavior)
Source: Brain and Behavior - February 8, 2024 Category: Neurology Authors: Roisin Vance,
Sarah Clarke,
Fiadhnait O'Keefe,
Toni Galligan,
Anne Doherty,
Cora Flynn,
Eric Kelleher,
Aoife Laffan,
Colin Doherty,
Diane Gillan Tags: ORIGINAL ARTICLE Source Type: research
Fatigue and long duration of infection are associated with worsen motor and non ‐motor symptoms in Parkinson's disease following Omicron COVID‐19 pandemic
ConclusionThis study confirms the impact of the Omicron COVID-19 pandemic on the motor and non-motor symptoms of PD, suggesting that management of related factors, including fatigue and duration of infection, may be beneficial in preventing or dealing with the exacerbation of PD symptoms after infection. (Source: Brain and Behavior)
Source: Brain and Behavior - February 7, 2024 Category: Neurology Authors: Wenbiao Xian,
Lishan Lin,
Wanling Wu,
Fengjuan Su,
Zhong Pei Tags: ORIGINAL ARTICLE Source Type: research
Exploring the associations between physical activity level, cognitive performance, and response to computerized cognitive training among chronic stroke patients
ConclusionThe results do not support that baseline physical activity level is a relevant predictor of the overall performance or response to CCT in this sample of chronic stroke patients. Similarly, the analyses revealed little evidence for an association between index stroke characteristics and future activity level in patients surviving mild-to-moderate stroke. (Source: Brain and Behavior)
Source: Brain and Behavior - February 7, 2024 Category: Neurology Authors: Anne ‐Marthe Sanders,
Geneviève Richard,
Knut Kolskår,
Kristine M. Ulrichsen,
Dag Alnæs,
Erlend S. Dørum,
Hege Ihle‐Hansen,
Mads L. Pedersen,
Jan Egil Nordvik,
Lars T. Westlye Tags: ORIGINAL ARTICLE Source Type: research
Effect of varicella ‐zoster virus infection and antiviral treatment on the risk for dementia: A meta‐analysis of observational studies
ConclusionThe association between VZV infection and dementia may be masked by antiviral treatment. Further studies with longer follow-up times that consider the severity of VZV infection and antiviral treatment are needed to clarify the contribution of VZV infection to the risk for dementia. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Li ‐fei Zhu,
Chuan‐cai Hu,
Yu Mei,
Min‐jing Zhu,
Ting‐yun Ye Tags: REVIEW Source Type: research
Prediction of clinical progression of subjective cognitive decline through alterations in morphology and structural covariance networks
ConclusionOur findings demonstrate that atrophy of the hippocampus and thinning of the cortex may serve as effective biomarkers for early identification of individuals at high risk of cognitive decline. Changes in connectivity within and outside of the DMN may play a crucial role in the pathophysiology of pSCD. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Zheqi Hu,
Xue Zhang,
Xinle Hou,
Lianlian Wang,
Haifeng Chen,
Lili Huang,
Dan Yang,
Yuting Mo,
Yun Xu,
Feng Bai Tags: ORIGINAL ARTICLE Source Type: research
Negative correlation between the Bern score and opening pressure in myelography positive spontaneous intracranial hypotension
ConclusionsA higher Bern score is indicative of not only an increased likelihood of a CSF leak but also a greater probability of low OP in patients with SIH. For patients with a Bern score ≥5 and positive heavily T2-weighted MR myelography findings, epidural blood patch is reasonable before invasive myelography. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Dan Zhang,
Qiaowei Zhang,
Feifang He,
Xingyue Hu,
Jin Wang Tags: ORIGINAL ARTICLE Source Type: research
Abnormal functional connectivity of the occipital thalamus with the superior occipital gyrus is associated with mild cognitive impairment in elderly individuals with primary insomnia
ConclusionThe early onset of cognitive impairment in patients with PI is associated with altered FC between the thalamus and the cortex. Enhanced FC between the thalamus and the visual cortex, that is, the superior occipital gyrus, which is involved in attentional processing, may play a role in the early onset of cognitive impairment in insomnia patients. Moreover, due to the fact that PI patients “overdraw” the compensatory capacity of these brain regions earlier, the PI–MCI may fall into the abyss of “decompensation” faster and face more severe cognitive impairments. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Lin Zhang,
Linxin Bai,
Zhenxing Guo,
Jiahui Gao,
Jingsong Wu,
Jia Huang,
Zhizhen Liu Tags: ORIGINAL ARTICLE Source Type: research
Visual Cognitive Assessment Test: Utility of the brief cognitive battery for early screening of cognitive impairment in Chongqing, China
ConclusionThe VCAT proves to be a reliable screening test for early cognitive impairment within our cohort. Being both language and cultural neutral, the VCAT has the potential to be utilized among a wider population within China. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Yidan Liu,
Binbin Xie,
Qin Li,
Shufang Xiao,
Jiamin Li,
Nagaendran Kandiah,
Kok Pin Ng,
Liumi Jiang,
Xiaofeng Li Tags: ORIGINAL ARTICLE Source Type: research
Herpes zoster vaccination and the risk of dementia: A systematic review and meta ‐analysis
ConclusionHerpes zoster vaccination is associated with a reduction of the risk of dementia. More epidemiological studies are needed to confirm the association. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Sangam Shah,
Krishna Dahal,
Sangharsha Thapa,
Prativa Subedi,
Basanta Sharma Paudel,
Swati Chand,
Amr Salem,
Markus Lammle,
Ranjit Sah,
Martin Krsak Tags: REVIEW Source Type: research
Impaired eye movements in Parkinson's disease and their relationship to top –down and bottom–up neural processing
ConclusionsPD's visual search movements may change depending on the meaningfulness of visual stimuli. Further, the abnormal visual search movements in PD may be due to insufficient bottom –up processing and excessive top–down processing.Plain Language SummaryParkinson's disease (PD) is a neurodegenerative disorder that can cause eye movement disorders. People with PD may have difficulty searching for and processing visual information. In this study, we investigated how meaningfulness affects visual search movements and visual information processing in people with PD. We measured eye movements and brain activity in resp...
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Nobuhiro Takahashi,
Mimpei Kawamura,
Yasutaka Kobayashi,
Masahito Hitosugi Tags: ORIGINAL ARTICLE Source Type: research
