White matter microstructure is differently associated with executive functioning in youth born with congenital heart disease and youth born preterm
ConclusionThe findings of this study suggest that microstructural alterations to association bundles, including lower myelination and axon density, have different relationships with executive functioning in youth with CHD and youth born preterm. Future studies should aim to characterize other neurobiological, social, and environmental influences that may interact with white matter microstructure and neuropsychological functioning in these at-risk individuals. (Source: Brain and Behavior)
Source: Brain and Behavior - November 24, 2023 Category: Neurology Authors: Kaitlyn Easson, May Khairy, Charles V. Rohlicek, Guillaume Gilbert, Annette Majnemer, Kim ‐Anh Nguyen, Thuy Mai Luu, Élise Couture, Anne‐Monique Nuyt, Sean C. L. Deoni, Maxime Descoteaux, Marie Brossard‐Racine Tags: ORIGINAL ARTICLE Source Type: research

Usage and impact of patient ‐reported outcomes in epilepsy
ConclusionsDifferences exist in attitudes and perspectives about PRO in epilepsy across Europe. An active plan is warranted to harmonize the measurement of PRO and ensure they can be relevant to people with epilepsy and health services. (Source: Brain and Behavior)
Source: Brain and Behavior - November 24, 2023 Category: Neurology Authors: Kristl Vonck, Arnaud Biraben, Magdalena Bosak, Poul J ørgen Jennum, Vasilios K Kimiskidis, Petr Marusic, James W. Mitchell, Lara N. Ferreira, Martina Ondrušová, Adrian Pana, Ulf Persson, Tim J. von Oertzen, Simona Lattanzi Tags: ORIGINAL ARTICLE Source Type: research

Acute stress symptoms in general population during the first wave of COVID lockdown in Italy: Results from the COMET trial
ConclusionsConcerns about the risk of infection as well as social isolation caused a higher incidence of acute post-traumatic stress symptoms that may predict the subsequent development of post-traumatic stress disorder symptoms in the long term. (Source: Brain and Behavior)
Source: Brain and Behavior - November 22, 2023 Category: Neurology Authors: Claudia Carmassi, Gaia Sampogna, Matteo Di Vincenzo, Salvatore Cipolla, Claudia Toni, Umberto Albert, Giuseppe Carr à, Francesca Cirulli, Bernardo Dell'Osso, Sara Fantasia, Maria Giulia Nanni, Virginia Pedrinelli, Maurizio Pompili, Gabriele Tags: ORIGINAL ARTICLE Source Type: research

Upregulation of Pin1 contributes to alleviation of cognitive dysfunction in diabetic mice
ConclusionPin1 can improve cognitive dysfunction in diabetic mice. (Source: Brain and Behavior)
Source: Brain and Behavior - November 22, 2023 Category: Neurology Authors: Dan Qiu, Tong Liu, Wei Qianping Tags: ORIGINAL ARTICLE Source Type: research

Greater socioenvironmental risk factors and higher chronic pain stage are associated with thinner bilateral temporal lobes
AbstractIntroduction: Previous research indicates ethnic/race group differences in pain and neurodegenerative diseases. Accounting for socioenvironmental factors reduces ethnic/race group differences in clinical and experimental pain. In the current study sample, we previously reported that in individuals with knee pain, ethnic/race group differences were observed in bilateral temporal lobe thickness, areas of the brain associated with risk for Alzheimer's disease, and related dementias. The purpose of the study was to determine if socioenvironmental factors reduce or account for previously observed ethnic/race group diffe...
Source: Brain and Behavior - November 21, 2023 Category: Neurology Authors: Lisa H. Antoine, Jared J. Tanner, Angela M. Mickle, Cesar E. Gonzalez, Daniel A. Kusko, Kristen Allen Watts, Deanna D. Rumble, Taylor L. Buchanan, Andrew M. Sims, Roland Staud, Song Lai, Hrishikesh Deshpande, Brandis Phillips, Thomas W. Bufor Tags: ORIGINAL ARTICLE Source Type: research

Identification of disordered profiles of gut microbiota and functional component in stroke and poststroke epilepsy
ConclusionThe disturbed gut microbiota and related dysfunctional components are closely associated with the progression of STR and PSE. (Source: Brain and Behavior)
Source: Brain and Behavior - November 21, 2023 Category: Neurology Authors: Duncan Wei, Xiaopu Chen, Jing Xu, Yongling Yin, Xiaotang Peng, Shunxian Li, Wenzhen He Tags: ORIGINAL ARTICLE Source Type: research

Genetic variation of the 5 ‐HT1A rs6295, 5‐HT2A rs6311, and CNR1 rs1049353 and an altered endocannabinoid system in depressed patients
ConclusionIn conclusion, it seems that the endocannabinoid system, especially the endocannabinoids 2-AG and AEA, and genetic variations of the 5-HT1A and 5-HT2A could play a role in patients with depression and may be involved in a depressive disorder. (Source: Brain and Behavior)
Source: Brain and Behavior - November 21, 2023 Category: Neurology Authors: Jasmin Obermanns, Hanna Meiser, Saskia Hoberg, Cynthia Segura Vesterager, Frank Schulz, Georg Juckel, Barbara Emons Tags: ORIGINAL ARTICLE Source Type: research

The effect of transcutaneous auricular vagus nerve stimulation on cycling ergometry and recovery in healthy young individuals
ConclusionIn our study, we saw that BS application gave positive results in reducing pain and fatigue due to cycling exercise compared to other applications. Similar results were obtained when we evaluated the data on a daily basis. We believe that VNS will be beneficial in reducing pain and fatigue, especially during and after the competition halftime. (Source: Brain and Behavior)
Source: Brain and Behavior - November 17, 2023 Category: Neurology Authors: Sefa Haktan Hatik, Mesut Asrlan, Ömer Demirbilek, Ali Veysel Özden Tags: ORIGINAL ARTICLE Source Type: research

Association between the blood pressure variability and cognitive decline in Parkinson's disease
Conclusion and implicationsHigher systolic VIM predicted a steeper decline in cognitive tests in PD-MCI independently from the mean value of blood pressure, orthostatic hypotension, and supine hypertension. (Source: Brain and Behavior)
Source: Brain and Behavior - November 16, 2023 Category: Neurology Authors: Yi Xiao, Tianmi Yang, Lingyu Zhang, Qianqian Wei, Ruwei Ou, Yanbing Hou, Kuncheng Liu, Junyu Lin, Qirui Jiang, Huifang Shang Tags: BRIEF REPORT Source Type: research

Impact of aversive affect on neural mechanisms of categorization decisions
ConclusionThese findings advance our knowledge of the neural mechanisms underlying affective responses in general and the influence of high affective salience on object representations and categorization decisions. (Source: Brain and Behavior)
Source: Brain and Behavior - November 16, 2023 Category: Neurology Authors: Daniel J. Levitas, Kess L. Folco, Thomas W. James Tags: ORIGINAL ARTICLE Source Type: research

Effects of different types of neonatal pain on somatosensory and cognitive development in male juvenile rats
ConclusionA combination of NP with inflammation occurring in the neonatal period might aggravate the adverse effects of each on somatosensory and cognitive development of rats, the mechanism of which might be associated with the increase of corticosterone secretion and the dysregulation of synaptic molecules. (Source: Brain and Behavior)
Source: Brain and Behavior - November 16, 2023 Category: Neurology Authors: Ru Ling, Yueshu Wang, Wen Zheng, Cuiting Min, Mengying Chen, Dongqing Xia, Xiaonan Li Tags: ORIGINAL ARTICLE Source Type: research

Proteomic and metabolomic characterizations of moyamoya disease patient sera
ConclusionsSignificant increases in pro-inflammatory and immunosuppressive abilities have been observed in patients with MMD, accompanied by significant reductions in anti-inflammatory and immune regulation. Various metabolites and proteins implicated in these processes have been identified for the first time. These findings hold immense significance for comprehending the pathogenesis of MMD and for the development of future drug therapies. (Source: Brain and Behavior)
Source: Brain and Behavior - November 14, 2023 Category: Neurology Authors: Qingbao Guo, Qian ‐Nan Wang, Jingjie Li, Simeng Liu, Xiaopeng Wang, Dan Yu, Zheng‐Xing Zou, Gan Gao, Qian Zhang, Fang‐Bin Hao, Jie Feng, Ri‐Miao Yang, Minjie Wang, Heguan Fu, Xiangyang Bao, Lian Duan Tags: ORIGINAL ARTICLE Source Type: research

Work ‐related factors and risk of amyotrophic lateral sclerosis: A multivariable Mendelian randomization study
ConclusionsOur MR analysis results demonstrate the potential causal relationship between jobs that involve heavy manual or physical work and ALS, which might be mediated by smoking and high systolic blood pressure. (Source: Brain and Behavior)
Source: Brain and Behavior - November 14, 2023 Category: Neurology Authors: Ming Li, Yile Liao, Zhangkun Luo, Hongfei Song, Zhi Yang Tags: ORIGINAL ARTICLE Source Type: research

Benefits of a mosaic approach for assessing cortical atrophy in individual multiple sclerosis patients
ConclusionThis study provides evidence that MAP yields high potential for a clinically relevant biomarker in MS, outperforming existing methods to compute cortical disease burden in single patients. Of note, MAP outputs brain maps illustrating individual cortical disease burden which can be directly interpreted in daily clinical routine. (Source: Brain and Behavior)
Source: Brain and Behavior - November 14, 2023 Category: Neurology Authors: Marlene Tahedl, Tun Wiltgen, Cui Ci Voon, Achim Berthele, Jan S. Kirschke, Bernhard Hemmer, Mark M ühlau, Claus Zimmer, Benedikt Wiestler Tags: ORIGINAL ARTICLE Source Type: research

Natural history of Duchenne muscular dystrophy in the United Kingdom: A descriptive study using the Clinical Practice Research Datalink
ConclusionsEstimates of mortality in UK-based DMD patients are age-specific in a uniquely large and nationally representative sample from the CPRD. (Source: Brain and Behavior)
Source: Brain and Behavior - November 14, 2023 Category: Neurology Authors: Jonathan Broomfield, Keith Abrams, Nick Latimer, Michela Guglieri, Mark Rutherford, Michael Crowther Tags: ORIGINAL ARTICLE Source Type: research