Enhancing the sensitivity of nanopipette biosensors for protein analysis
ConclusionThis study offers valuable insights into biomolecule transport through nanopipettes, enhances our understanding of protein dynamics in restricted environments, and significantly contributes to single-protein sequencing studies, drug screening, and proteomics. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Mustafa Demirtas Tags: ORIGINAL ARTICLE Source Type: research
Perceived cognitive performance in off ‐prescription users of modafinil and methylphenidate: an online survey
ConclusionThese findings suggest that at least some reported off-prescription users of modafinil and methylphenidate may be seeking to reduce the impact of self-perceived poorer performance, particularly in forms of cognition that are likely to impact on self-directed or self-motivated work. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Rachel D. Teodorini,
Nicola Rycroft,
James H. Smith ‐Spark Tags: ORIGINAL ARTICLE Source Type: research
Efficacy of robot ‐assisted minimally invasive stereotactic puncture therapy for supratentorial hypertensive intracerebral hemorrhage
ConclusionThe main advantages of robot-assisted MISPT for supratentorial HICH were shown in minimally invasive, precision, and low incidences of complications. In addition, it may improve the prognosis significantly. Thus, it has great potential to be popularized and clinically applied in the future. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Weiyi Han,
Aotan Xie,
Taoli Chen,
Xiao Sun,
Xianzhi Liu Tags: ORIGINAL ARTICLE Source Type: research
Correlation between serum ANGPTL4 levels and white matter hyperintensity and cognitive impairment in patients with cerebral small vessel disease
ConclusionANGPTL4 may be involved in the process of white matter damage and CI in CSVD patients and shows a diagnostic value for CSVD-CI. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Jianhua Zhao,
Shiyun Zhang,
Xiaoting Wang,
Minghua Wang,
Zehua Wang,
Ruotai Li,
Yuxi Liu,
Chengbiao Lu,
Shaomin Li Tags: ORIGINAL ARTICLE Source Type: research
A novel synthetic oleanane triterpenoid, 2 ‐cyano‐3,12‐dioxoolean‐1,9‐dien‐28‐oic acid, regulates mechanical allodynia by rescuing neuronal cell death and glial cell activation in the spinal cord of resiniferatoxin‐treated rats
ConclusionsOur study provides a novel result that a synthetic triterpenoid, CDDO, can interfere neuronal cell death and glial cell activation in the spinal cord of RTX-treated rats. Hence, CDDO is an alternative therapeutic choice for PHN. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Ying ‐Yi Lu,
Chia‐Yang Lin,
Hung‐Pei Tsai,
Chih‐Lung Lin,
Chieh‐Hsin Wu Tags: ORIGINAL ARTICLE Source Type: research
Regional MRI volumetry using NeuroQuant versus visual rating scales in patients with cognitive impairment and dementia
ConclusionsThe findings of this study encourage the use of regional automatic volumetry in locations lacking neuroradiologists with experience in the rating of atrophy typical of neurodegenerative diseases, and in primary care settings. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Karin Persson,
Maria L. Barca,
Trine Holt Edwin,
Lena Cavallin ‐Eklund,
Gro Gujord Tangen,
Hanneke F. M. Rhodius‐Meester,
Geir Selbæk,
Anne‐Brita Knapskog,
Knut Engedal Tags: ORIGINAL ARTICLE Source Type: research
Clinical characteristics of persistent postural ‐perceptual dizziness and its visual subtype in Korean patients: A multicenter cross‐sectional study
ConclusionThis is the first comprehensive nationwide study examining clinical features of both definite PPPD patients and its clinical variants, considering visual exacerbating factors. Differences in dizziness and personality traits emerged between definite PPPD and its potential variant without visual issues. Our results highlight the possibility of a distinct clinical variant of PPPD influenced by visual dependency. (Source: Brain and Behavior)
Source: Brain and Behavior - February 1, 2024 Category: Neurology Authors: Joo Hyun Park,
Thanh Tin Nguyen,
Sung ‐Hee Kim,
Ji‐Yun Park,
Seunghee Na,
Eun‐Ju Jeon,
Ji won Seo,
Chang Gun Cho,
Se‐Joon Oh,
Sung‐Won Choi,
Kwang‐Dong Choi,
Seo‐Young Choi,
Ji Eun Choi,
Sung‐Kwang Hong,
Won‐Ho Chung,
Youn Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
(Source: Brain and Behavior)
Source: Brain and Behavior - January 30, 2024 Category: Neurology Tags: ISSUE INFORMATION Source Type: research
Investigating the neuroprotective potential of rAAV2 ‐PCBP1‐EGFP gene therapy against a 6‐OHDA‐induced model of Parkinson's disease
ConclusionsIn conclusion, our findings provide compelling evidence for the beneficial effects of PCBP1 in the PD model, suggesting that PCBP1 could be a potential therapeutic target for PD. (Source: Brain and Behavior)
Source: Brain and Behavior - January 29, 2024 Category: Neurology Authors: Ling ‐Yun Ma,
Lanying Wang,
Jiantao Liang,
Lirong Huo Tags: ORIGINAL ARTICLE Source Type: research
Functional seizures: Are they consistent over time?
ConclusionsOur results show that FS tends to remain consistent in a single patient even after several years, and there is probably no correlation between the degree of consistency and the time between VEEG sessions. These findings have implications for supporting the concept of FS as a consistent phenomenon. Additionally, they may suggest potential avenues for future research to elucidate the origins of FS. Subsequent studies are essential to validate and expand upon these preliminary observations. (Source: Brain and Behavior)
Source: Brain and Behavior - January 29, 2024 Category: Neurology Authors: Elian Bahous,
Raz Wagner,
Moshe Herskovitz Tags: ORIGINAL ARTICLE Source Type: research
Identification and validation of cortisol ‐related hub biomarkers and the related pathogenesis of biomarkers in Ischemic Stroke
ConclusionFour cortisol-related hub biomarkers are identified in this study, which provides new ideas for the key changes of cortisol during the occurrence of IS. (Source: Brain and Behavior)
Source: Brain and Behavior - January 29, 2024 Category: Neurology Authors: Jing ‐Jing Wang,
Fang‐Biao Xu,
Sen Hu,
Yu‐Ming Xu,
Xin‐Zhi Wang Tags: ORIGINAL ARTICLE Source Type: research
Shared genetic risk between anorexia nervosa and cardiovascular disease events: Evidence from genome ‐wide association studies
DiscussionSome loci affect the liability to AN and CVD in opposite directions and the shared genetic effects may not be consistent across all CVD events. Our results provide further evidence suggesting that the elevated cardiovascular risk in AN may not be due to shared genetic underpinnings, but more likely a downstream consequence of the disease. (Source: Brain and Behavior)
Source: Brain and Behavior - January 29, 2024 Category: Neurology Authors: Baiyu Qi,
Mariaelisa Graff,
Eating Disorders Working Group of the Psychiatric Genomics Consortium,
Cynthia M Bulik,
Kari E North,
Melissa A Munn ‐Chernoff Tags: BRIEF REPORT Source Type: research
Combination of different noninvasive brain stimulation treatments for upper limb recovery in stroke patients: A systematic review
We report a review of Pubmed (Medline), CENTRAL, Web of Science, and Scopus to test the effectiveness of the combined application of repetitive transcranial magnetic stimulation and transcranial direct current stimulation in the improvement of different functional variables of the upper limb in people with stroke. Two independent reviewers assessed eligibility and evaluated the quality of the studies. Five articles were included in the final review according to the inclusion criteria: Most show statistically significant differences in motor function improvement in favor of the experimental group, but not in activity. Due t...
Source: Brain and Behavior - January 29, 2024 Category: Neurology Authors: Ler ín‐Calvo Alfredo,
Rodríguez‐Martínez David,
Bernal‐Jiménez Juan‐José,
Lerma‐Lara Sergio,
Ferrer‐Peña Raúl Tags: REVIEW Source Type: research
Functional neural networks stratify Parkinson's disease patients across the spectrum of cognitive impairment
ConclusionWe propose that resting-state networks (RSN) can be a discriminating factor in distinguishing the CI stages of PD and progressing from PD-NC to MCI or PDD. The integration of clinical and neuroimaging data may enhance the early detection of PD in clinical settings and potentially prevent the disease from advancing to more severe stages. (Source: Brain and Behavior)
Source: Brain and Behavior - January 25, 2024 Category: Neurology Authors: Farzin Hajebrahimi,
Miray Budak,
Mevhibe Saricaoglu,
Zeynep Temel,
Tugce Kahraman Demir,
Lutfu Hanoglu,
Suleyman Yildirim,
Zubeyir Bayraktaroglu Tags: ORIGINAL ARTICLE Source Type: research
Facial emotion recognition is associated with executive functions and depression scores, but not staging of dementia, in mild ‐to‐moderate Alzheimer's disease
ConclusionsThis study demonstrated a decreased FER ability in patients with AD. The critical point in FER deficits is the presence of dementia, not the dementia stage, in AD. It has been determined that executive functions and depression (even at a subsyndromal level), which have limited knowledge, are associated with FER abilities. (Source: Brain and Behavior)
Source: Brain and Behavior - January 25, 2024 Category: Neurology Authors: İsmail Buçgün,
Şükrü Alperen Korkmaz,
Demet Güleç Öyekçin Tags: ORIGINAL ARTICLE Source Type: research
