Blocking salt ‐inducible kinases with YKL‐06‐061 prevents PTZ‐induced seizures in mice
ConclusionOur findings provide the first evidence that SIK1 affects gene regulation in neuronal hyperactivity, which is involved in seizure behavior. Targeting SIK1 through the development of selective inhibitors may lead to disease-modifying therapies that reduce epilepsy progression. (Source: Brain and Behavior)
Source: Brain and Behavior - November 3, 2023 Category: Neurology Authors: Lixuan Peng,
Cai Li,
Xiaohan Tang,
Yuyan Xiang,
Yang Xu,
Wenyu Cao,
Huamao Zhou,
Suyun Li Tags: ORIGINAL ARTICLE Source Type: research
Postoperative fibrinogen ‐to‐albumin ratio acting as an indicator of futile recanalization in patients with successful thrombectomy
ConclusionOur findings support high postoperative FAR serving as an indicator of futile recanalization in patients with anterior circulation large-vessel occlusion and successful thrombectomy. (Source: Brain and Behavior)
Source: Brain and Behavior - November 2, 2023 Category: Neurology Authors: Tao Tang,
Di Li,
Tie ‐Ping Fan,
Lin‐Jia Guo,
Xiao‐Yan Lan,
Cong‐Jie Bi,
Johannes Boltze,
Aline M. Thomas,
Xu‐Sheng Zhao,
Ming Mo,
Man‐Hong Zhao,
Xun‐Ming Ji,
Shen Li Tags: ORIGINAL ARTICLE Source Type: research
Anxiety, depression symptoms, and psychological resilience among hospitalized COVID ‐19 patients in isolation: A study from Wuhan, China
ConclusionPatients with COVID-19 exhibit elevated levels of both anxiety and depression. Notably, psychological resilience emerges as a protective factor against the development of anxiety and depression. (Source: Brain and Behavior)
Source: Brain and Behavior - November 1, 2023 Category: Neurology Authors: Li Chen,
Zhenmeng Wang,
Dan Liu,
Dandan He,
Shulin Du,
Zezhi Li,
Shuyun Li,
Yuehong Sheng Tags: ORIGINAL ARTICLE Source Type: research
A novel nonsense variant in NSD1 gene in a female child with Sotos syndrome: A case report and literature review
DiscussionThe lack of correlation between mutation sites or types and phenotypes was summarized by literature reviewing. The NSD1 protein contains 14 functional domains and this nonsense mutation was located in SET domain. Early appearance of the termination codon leads to protein truncation. Haploinsufficiency of theNSD1 gene causes the overgrowth disorders. (Source: Brain and Behavior)
Source: Brain and Behavior - November 1, 2023 Category: Neurology Authors: Xinting Liu,
Chen Chen,
Lin Wan,
Gang Zhu,
Yan Zhao,
Lizhu Hu,
Yan Liang,
Jing Gao,
Jing Wang,
Guang Yang Tags: ORIGINAL ARTICLE Source Type: research
fNIRS ‐based evaluation of the impact of SARS‐CoV‐2 infection central auditory processing
ConclusionSARS-CoV-2 infections may impact on central auditory processing or auditory attention due to changes in oxyhemoglobin levels in the frontal and temporal brain regions. It seems that SARS-CoV-2 infection is associated with an additional load on neural activity, and difficulties in focusing in auditory attention, following speech and hearing in noise as well as increased effort to perceive auditory cues. (Source: Brain and Behavior)
Source: Brain and Behavior - November 1, 2023 Category: Neurology Authors: Handan Yaman,
O ğuz Yılmaz,
Lütfü Hanoğlu,
Yıldırım Bayazıt Tags: ORIGINAL ARTICLE Source Type: research
The causal effects between selenium levels and the brain cortical structure: A two ‐sample Mendelian randomization study
This study utilizes 11 genetic variants associated with Se level variations, extracted from a large-scale genome-wide association study (GWAS) encompassed circulating Se levels (n = 5477) and toenail Se levels (n = 4162) in the European population. Outcome data were sourced from the summary statistics of the ENIGMA Consortium, comprising GWAS data from 51,666 individuals. The variables include cortical surface area (SA), thickness (TH) at the global level, and 34 functional cortical regions evaluated by m agnetic resonance imaging. The inverse-variance-weighted method was used as the primary estimate. Additionally, sen...
Source: Brain and Behavior - October 31, 2023 Category: Neurology Authors: Xiaowei Zhang,
Yuqing Zhong,
Kejun He Tags: ORIGINAL ARTICLE Source Type: research
Seipin overexpression attenuates cerebral ischemia ‐reperfusion injury via preventing apoptosis and autophagy
ConclusionSeipin has a protective role against CI/RI in rats, and its mechanism might be relevant to the suppression of apoptosis and autophagy, suggesting that seipin might be a latent target for CI/RI. (Source: Brain and Behavior)
Source: Brain and Behavior - October 28, 2023 Category: Neurology Authors: Xiaoxi Zhu,
Xiaoqiong An,
Ming Chen,
Dongfen Guo,
Peng Xie,
Bi Wang,
Zhi Huang,
Wenfeng Yu Tags: ORIGINAL ARTICLE Source Type: research
Dual ‐task difficulties as a risk factor for unemployment in people with multiple sclerosis
ConclusionCognitive function, as opposed to motor function, has been found to be a significant predictor of unemployment in pwMS. (Source: Brain and Behavior)
Source: Brain and Behavior - October 26, 2023 Category: Neurology Authors: Turhan Kahraman,
Hasretgul Temiz,
Zuhal Abasiyanik,
Cavid Baba,
Serkan Ozakbas Tags: ORIGINAL ARTICLE Source Type: research
Visual search strategies of performance monitoring used in action anticipation of basketball players
ConclusionThe experts could monitor the performance of prediction by grabbing vital shooting information (such as the body of a player). The results suggest the athletes and coaches that if they want to improve the ability of prediction, it may be useful to shift their focus of attention from ball trajectory to body action. (Source: Brain and Behavior)
Source: Brain and Behavior - October 24, 2023 Category: Neurology Authors: Yawei Li,
Tian Feng,
Fuchun Zhang,
Umer Asgher,
Bingbing Yan,
Tianyu Peng Tags: ORIGINAL ARTICLE Source Type: research
Persistent post ‐COVID headache is associated with suppression of scale‐free functional brain dynamics in non‐hospitalized individuals
ConclusionsThese findings provide new insights into the neurophysiological mechanisms that underlie persistent post-COVID headache, with reduced BOLD scaling as a potential biomarker that is specific to this debilitating condition. (Source: Brain and Behavior)
Source: Brain and Behavior - October 24, 2023 Category: Neurology Authors: Nathan W. Churchill,
Eugenie Roudaia,
J. Jean Chen,
Asaf Gilboa,
Allison Sekuler,
Xiang Ji,
Fuqiang Gao,
Zhongmin Lin,
Mario Masellis,
Maged Goubran,
Jennifer S. Rabin,
Benjamin Lam,
Ivy Cheng,
Robert Fowler,
Chris Heyn,
Sandra E. Black,
B Tags: ORIGINAL ARTICLE Source Type: research
Lifetime and past ‐month alcohol use and related factors among female sex workers in Iran
ConclusionAlcohol use is prevalent among FSWs in Iran. Further prevention programs are needed to address and reduce harms associated with alcohol use among this vulnerable population in Iran. Designing intervention programs, it is suggested to consider other variables affecting alcohol use in FSWs. (Source: Brain and Behavior)
Source: Brain and Behavior - October 24, 2023 Category: Neurology Authors: Mohammad Aziz Rasouli,
Bushra Zareie,
Mohammad Mehdi Gouya,
Fatemeh Hadavandsiri,
Marzieh Mahboobi,
Yousef Moradi,
Rozhin Moradi,
Ghobad Moradi Tags: ORIGINAL ARTICLE Source Type: research
Functional brain changes after alternative pharmacological interventions in posttraumatic stress disorder: A systematic review of clinical trials
ConclusionsThis systematic review identified preliminary evidence for normalizing brain function after the use of alternative pharmacological agents. Importantly, sex-specific differences were noted, in particular when using oxytocin, that will require further investigation. (Source: Brain and Behavior)
Source: Brain and Behavior - October 21, 2023 Category: Neurology Authors: Shahab Lotfinia,
Amin Afshar,
Aram Yaseri,
Miranda Olff,
Yann Quid é Tags: REVIEW Source Type: research
Changes in serum levels of pain mediators in hemiplegic shoulder pain
ConclusionPatients with HSP have a higher risk of joint mobility disorders and depression; spasticity may be an important factor in the development of shoulder pain; CGRP is thought to be the major pain mediator in HSP, and HSP may not be inflammatory. (Source: Brain and Behavior)
Source: Brain and Behavior - October 21, 2023 Category: Neurology Authors: Mincong Lei,
Yidi Wang,
Qian Chen,
Peng Huang,
Yige Li,
Yuanyuan Jia,
Dianhuai Meng Tags: ORIGINAL ARTICLE Source Type: research
Sex ‐specific differences in pain localization in female patients with endometriosis: A comparison of sexless and female human body outlines
ConclusionsThe findings suggest that differences in the resulting areas marked in the pain drawings were negligible and the preferences for sexless pain drawings were not significant, so that a sexless body outline for pain drawings could be a good choice, especially when a study does not focus on one specific sex. (Source: Brain and Behavior)
Source: Brain and Behavior - October 19, 2023 Category: Neurology Authors: Natasza Szczypien,
Zoe Ruchay,
Zino Ruchay,
Sandra Verena M üller,
Claudia Kaiser,
Frank Klawonn Tags: ORIGINAL ARTICLE Source Type: research
Factors influencing cognitive function in patients with Huntington's disease from China: A cross ‐sectional clinical study
ConclusionCognitive impairment was very common in Chinese HD patients at the first visit and worse in the patients in advanced phase. The severity of motor symptoms and functional capacity were correlated to the diverse cognitive domains. (Source: Brain and Behavior)
Source: Brain and Behavior - October 18, 2023 Category: Neurology Authors: Yang ‐Fan Cheng,
Kun‐Cheng Liu,
Tian‐Mi Yang,
Yi Xiao,
Qi‐Rui Jiang,
Jing‐Xuan Huang,
Sirui Zhang,
Qian‐Qian Wei,
Ru‐Wei Ou,
Chun‐Yu Li,
Xiao‐Jing Gu,
Jean‐Marc Burgunder,
Hui‐Fang Shang Tags: ORIGINAL ARTICLE Source Type: research
