Values and diagnostic accuracy of sensory nerve action potentials in control participants and participants with diabetes with and without clinical diabetic neuropathy, based on neuropathy scale measurements
ConclusionSural nerve had a high specificity for neuropathy; however, the CSPNI had the highest specificity and PPV, whereas the SPS had the highest sensitivity and NPV. (Source: Brain and Behavior)
Source: Brain and Behavior - February 14, 2024 Category: Neurology Authors: Ahmad R. Abuzinadah,
Moafaq S. Alrawaili,
Aysha A. Alshareef,
Hussien S. Alkully,
Haneen Milyani,
Bashayr Alamri,
Weam Alshora,
Ahmed K. Bamaga Tags: ORIGINAL ARTICLE Source Type: research
Comment on: “Gout/hyperuricemia reduces the risk of Alzheimer's disease: A meta‐analysis based on latest evidence”
(Source: Brain and Behavior)
Source: Brain and Behavior - February 13, 2024 Category: Neurology Authors: Zain Ali Nadeem,
Abdulqadir J. Nashwan Tags: COMMENTARY Source Type: research
Causal association between systemic lupus erythematosus and the risk of migraine: A Mendelian randomization study
ConclusionsOur study indicates that genetic susceptibility to SLE increases the incidence of migraine with aura but not migraine without aura. It is necessary for the routine evaluation and early recognition of migraine in patients with SLE in clinical settings. (Source: Brain and Behavior)
Source: Brain and Behavior - February 13, 2024 Category: Neurology Authors: Meixuan Ren,
Hangtian Yu,
Bing Xiao,
Yan Zhao,
Jiewei Yan,
Jianghong Liu Tags: ORIGINAL ARTICLE Source Type: research
Prevalence of the use of prescription stimulants as “study drugs” by UK university students: A brief report
ConclusionThere is a clear need for large-scale research in this area, using representative sampling and survey methods that protect student anonymity. (Source: Brain and Behavior)
Source: Brain and Behavior - February 13, 2024 Category: Neurology Authors: Ffinian Jones,
Philip M. Newton Tags: BRIEF REPORT Source Type: research
Serum Galectin ‐1, Galectin‐9, and YKL‐40 levels in bipolar disorder and their relationship with cognitive functions
Discussion and conclusionStatistically significant low levels of serum Galectin-1, Galectin-9, and YKL-40 detected in the patient group suggest that these parameters have important roles in neuroinflammation. The statistically higher Stroop and trail-making test scores of the patient group compared to the control group indicates that the cognitive performance of the patient group was weaker. Also, the positive correlation between Galectin-1, Galectin-9, and YKL-40 levels and cognitive performance suggests that these molecules may have a neuroprotective role. We think that the present study will contribute to this field whe...
Source: Brain and Behavior - February 13, 2024 Category: Neurology Authors: Elcicek Selahaddin,
Demir Bahadir,
Sahin Sengul,
Taysi Seyithan,
Ulusal Hasan,
Elboga G ülcin,
Altindag Abdurrahman Tags: ORIGINAL ARTICLE Source Type: research
Calcitriol restrains microglial M1 polarization and alleviates dopaminergic degeneration in hemiparkinsonian mice by boosting regulatory T ‐cell expansion
ConclusionThese findings suggest that calcitriol's anti-inflammatory and neuroprotective effects in PD are associated with its potential to boost Treg expansion. (Source: Brain and Behavior)
Source: Brain and Behavior - February 13, 2024 Category: Neurology Authors: Yangzhi Xie,
Liang Chen,
Jiacheng Chen,
Yongjun Chen Tags: ORIGINAL ARTICLE Source Type: research
Plasma SOMAmer proteomics of postoperative delirium
ConclusionIn older patients who have undergone major surgery, plasma SOMAmer proteomics may provide a relatively non-invasive benchmark to identify biomarkers associated with postoperative delirium. (Source: Brain and Behavior)
Source: Brain and Behavior - February 13, 2024 Category: Neurology Authors: Jacqueline M. Leung,
Julio C. Rojas,
Laura P. Sands,
Brandon Chan,
Binita Rajbanshi,
Zhiyuan Du,
Pang Du,
the Perioperative Medicine Research group Tags: ORIGINAL ARTICLE Source Type: research
Pregnancy ‐related knowledge in women with epilepsy in childbearing age: A pilot questionnaire survey from China
ConclusionIn our study, the understanding of pregnancy-related knowledge did not differ from WWE and their caregivers, both are far from satisfactory in certain areas. It is urgent for WWE and their caregivers to improve their pregnancy-related knowledge of epilepsy. As their primary access is from knowledgeable health care professionals like neurologists, well-trained neurologists in epilepsy management during pregnancy are in need. (Source: Brain and Behavior)
Source: Brain and Behavior - February 11, 2024 Category: Neurology Authors: Qiwei Li,
Yina Cao,
Jingxin Zhang,
Yanlu Fu,
Beibei Shen,
Shuang Wang,
Jiajia Fang Tags: ORIGINAL ARTICLE Source Type: research
Causal relationship between inflammatory factors and cerebral small vessel disease: Univariate, multivariate, and summary ‐data‐based mendelian randomization analysis
ConclusionAccording to MR and SMR analysis, higher levels of TRAIL increased the risk of SVS by upregulating gene expression of KNG1 in brain cortex tissues. In addition, protective effects of E-selectin and IL-3a levels on WMPVS were regulated by increased DNA methylation of gene ABO in blood tissue. (Source: Brain and Behavior)
Source: Brain and Behavior - February 10, 2024 Category: Neurology Authors: Tian ‐Ci Qiao,
Hao‐Yu Tian,
Shi‐Zhe Shan,
Li‐Li Shan,
Zheng‐Yu Peng,
Jia Ke,
Meng‐Ting Li,
Yang Wu,
Yan Han Tags: ORIGINAL ARTICLE Source Type: research
Correlation analysis between cerebral microangiopathy and autonomic nervous dysfunction
ConclusionWe demonstrates that age, history of leukoaraiosis, cognitive function assessment, blood uric acid, Hcy level, 24-h SBPSD, dSBPSD, nSBPSD, blood pressure, SDNN, RMSSD, HF, LF, and coronary heart disease were highly associated with cerebral microangiopathy with autonomic dysfunction. Furthermore, the influencing factors of cerebral microangiopathy with autonomic dysfunction are age, history of leukoaraiosis, ASP score, SSR, blood pressure variability, and HRV. (Source: Brain and Behavior)
Source: Brain and Behavior - February 10, 2024 Category: Neurology Authors: Na Liu,
Hongmin Wang,
Bing Han,
Wenyuan Wang,
Moqing Zhou,
Lin Yang,
Yanyong Wang Tags: ORIGINAL ARTICLE Source Type: research
UK Medical Cannabis Registry: Assessment of clinical outcomes in patients with insomnia
ConclusionPatients with insomnia experienced an improvement in sleep quality following the initiation of CBMPs in this medium-term analysis. Fewer than 15% of participants reported one or more adverse events. However, due to the limitations of the study design, further investigation is required before definitive conclusions can be drawn on the efficacy of CBMPs in treating insomnia. (Source: Brain and Behavior)
Source: Brain and Behavior - February 10, 2024 Category: Neurology Authors: Kavyesh Vivek,
Zekiye Karagozlu,
Simon Erridge,
Carl Holvey,
Ross Coomber,
James J. Rucker,
Mark W. Weatherall,
Mikael H Sodergren Tags: ORIGINAL ARTICLE Source Type: research
Attitudes and perceptions of Irish health care professionals regarding functional neurological disorder: A national survey
ConclusionThis study indicates that there is a significant need to improve FND education among HCPs in Ireland, in addition to developing appropriately resourced, integrated, multidisciplinary care pathways for the FND patient group. (Source: Brain and Behavior)
Source: Brain and Behavior - February 8, 2024 Category: Neurology Authors: Roisin Vance,
Sarah Clarke,
Fiadhnait O'Keefe,
Toni Galligan,
Anne Doherty,
Cora Flynn,
Eric Kelleher,
Aoife Laffan,
Colin Doherty,
Diane Gillan Tags: ORIGINAL ARTICLE Source Type: research
Fatigue and long duration of infection are associated with worsen motor and non ‐motor symptoms in Parkinson's disease following Omicron COVID‐19 pandemic
ConclusionThis study confirms the impact of the Omicron COVID-19 pandemic on the motor and non-motor symptoms of PD, suggesting that management of related factors, including fatigue and duration of infection, may be beneficial in preventing or dealing with the exacerbation of PD symptoms after infection. (Source: Brain and Behavior)
Source: Brain and Behavior - February 7, 2024 Category: Neurology Authors: Wenbiao Xian,
Lishan Lin,
Wanling Wu,
Fengjuan Su,
Zhong Pei Tags: ORIGINAL ARTICLE Source Type: research
Exploring the associations between physical activity level, cognitive performance, and response to computerized cognitive training among chronic stroke patients
ConclusionThe results do not support that baseline physical activity level is a relevant predictor of the overall performance or response to CCT in this sample of chronic stroke patients. Similarly, the analyses revealed little evidence for an association between index stroke characteristics and future activity level in patients surviving mild-to-moderate stroke. (Source: Brain and Behavior)
Source: Brain and Behavior - February 7, 2024 Category: Neurology Authors: Anne ‐Marthe Sanders,
Geneviève Richard,
Knut Kolskår,
Kristine M. Ulrichsen,
Dag Alnæs,
Erlend S. Dørum,
Hege Ihle‐Hansen,
Mads L. Pedersen,
Jan Egil Nordvik,
Lars T. Westlye Tags: ORIGINAL ARTICLE Source Type: research
Effect of varicella ‐zoster virus infection and antiviral treatment on the risk for dementia: A meta‐analysis of observational studies
ConclusionThe association between VZV infection and dementia may be masked by antiviral treatment. Further studies with longer follow-up times that consider the severity of VZV infection and antiviral treatment are needed to clarify the contribution of VZV infection to the risk for dementia. (Source: Brain and Behavior)
Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Li ‐fei Zhu,
Chuan‐cai Hu,
Yu Mei,
Min‐jing Zhu,
Ting‐yun Ye Tags: REVIEW Source Type: research
