Filtered By:
Specialty: Biology

This page shows you your search results in order of date. This is page number 18.

Order by Relevance | Date

Total 656 results found since Jan 2013.

Sex differences in the expression of cell adhesion molecules on microvesicles derived from cultured human brain microvascular endothelial cells treated with inflammatory and thrombotic stimuli
ConclusionsThere are sex differences in expression of cell adhesion molecules on MV released from HBMEC under control conditions and upon activation by TNF α or THR. MV taken up by unstimulated HBMEC may impact the integrity of the brain microvasculature and account, in part, for sex differences in vascular pathologies in the brain.
Source: Biology of Sex Differences - May 21, 2019 Category: Biology Source Type: research

Blood proteins help predict risk of developing heart failure
(Baylor College of Medicine) Two blood proteins help predict more accurately the risk for heart attack, stroke and heart failure hospitalization.
Source: EurekAlert! - Biology - May 21, 2019 Category: Biology Source Type: news

GW researcher seeks to improve diagnostic utility of neonatal EEGs
(George Washington University) A researcher at the GW School of Medicine and Health Sciences is working to improve diagnostic utility of neonatal EEGs thanks to grant awards from the National Eye Institute and the National Institute of Neurological Disorders and Stroke.
Source: EurekAlert! - Biology - May 15, 2019 Category: Biology Source Type: news

Selenoprotein T as a new positive inotrope in the goldfish Carassius auratus RESEARCH ARTICLE
This study aimed to evaluate the cardiac expression of SELENOT, and the effects of exogenous PSELT (a 43-52 SELENOT derived-peptide) on the heart function of C. auratus, a hypoxia tolerance fish model. We found that SELENOT was expressed in cardiac extracts of juvenile and adult fish, located in the sarcoplasmic reticulum (SR) together with calsequestrin-2. Expression increased under acute hypoxia. On ex vivo isolated and perfused goldfish heart preparations, under normoxia, PSELT dose-dependently increased Stroke Volume (SV), Cardiac Output (Q), and Stroke Work (SW), by involving cAMP, PKA, L-type calcium channels, SERCA2...
Source: Journal of Experimental Biology - May 12, 2019 Category: Biology Authors: Rosa, M., Alfonsina, G., Sandra, I., Loubna, B., Serena, L., Yamine, M. B., Mariacristina, F., Carmine, R., Tommaso, A., Youssef, A., Carmela, C. M. Tags: RESEARCH ARTICLE Source Type: research

Identification of avian flapping motion from non-volant winged dinosaurs based on modal effective mass analysis
by Yaser Saffar Talori, Jing-Shan Zhao, Yun-Fei Liu, Wen-Xiu Lu, Zhi-Heng Li, Jingmai Kathleen O'Connor The origin of avian flight is one of the most controversial debates in Paleontology. This paper investigates the wing performance ofCaudipteryx, the most basal non-volant dinosaur with pennaceous feathered forelimbs by using modal effective mass theory. From a mechanical standpoint, the forced vibrations excited by hindlimb locomotion stimulate the movement of wings, creating a flapping-like motion in response. This shows that the origin of the avian flight stroke should lie in a completely natural process of active loc...
Source: PLoS Computational Biology - May 1, 2019 Category: Biology Authors: Yaser Saffar Talori Source Type: research

Neurological Deficit and Structural Changes in Lymphoid Structures of the Tracheal Wall in the Immediate Stage of Experimental Hemorrhagic Stroke in Rats with Different Behavioral Activity
Specific features of neurological deficit and changes in the cellular composition of tracheal lymphoid structures during the immediate stage (day 1) of hemorrhagic stroke were studied in rats with various behavioral parameters. Modeling of hemorrhage in the left caudate nucleus of the brain was followed by the development of motor disturbances in the forelimb use asymmetry test and corner rotation paradigm. These animals preferred to use the left forelimb (ipsilateral to the side of hemorrhage) to lean on the cylinder wall. The frequency of using the right forelimb or both forelimbs was reduced under these conditions. The ...
Source: Bulletin of Experimental Biology and Medicine - April 23, 2019 Category: Biology Source Type: research

ERK activation by zeranol has neuroprotective effect in cerebral ischemia reperfusion
In this study we used zeranol to protect ovariectomized (OVX) rats against cerebral I/R damage and our target is to identify the mechanism of its protection, in addition to investigating whether this mechanism inhibits inflammation (by preventing glial cell activation) and apoptosis.Main methodsFirst 18 ovariectomized rats were allocated into 3 groups: I/R group, zeranol+ I/R group and U0126, MEK1/2 inhibitor + zeranol+ I/R group. After 24 h reperfusion, protein expression of total extracellular signal-regulated protein kinase (t-ERK1/2), phosphorylated extracellular signal-regulated protein kinase (p-ERK1/2), Bcl-2, and...
Source: Life Sciences - April 19, 2019 Category: Biology Source Type: research

NLRP3 inflammasome activates interleukin-23/interleukin-17 axis during ischaemia-reperfusion injury in cerebral ischaemia in mice
Publication date: Available online 16 April 2019Source: Life SciencesAuthor(s): Haining Wang, Di Zhong, Hongping Chen, Jing Jin, Qingqing Liu, Guozhong LiAbstractAimsNLRP3 inflammasome has been reported associated with some inflammatory and autoimmune diseases. We previously researches showed that interleukin-23 (IL-23) and interleukin-17 (IL-17) aggravates the ischaemic injury of the brain tissue. However, it is poorly understood whether the NLPR3 inflammasome was involved in regulating and activating the IL-23/IL-17 axis in ischaemic stroke. We aimed to delineate whether the NLRP3 inflammasome signalling provokes the IL-...
Source: Life Sciences - April 17, 2019 Category: Biology Source Type: research

Chrysin prevents cognitive and hippocampal long-term potentiation deficits and inflammation in rat with cerebral hypoperfusion and reperfusion injury
ConclusionOur data confirm that chrysin could prevent brain inflammation and thereby prevents cognitive and LTP impairments due to cerebral ischemia. So it could be a promising neuroprotective agent against cerebrovascular insufficiency states.
Source: Life Sciences - April 13, 2019 Category: Biology Source Type: research

Association between PDE4D polymorphism and ischemic stroke in young population
ConclusionWe found an association between SNP83 and the risk of IS in Chinese young population from northern Henan province. There was not a significant association between SNP87 and IS in Chinese young population.
Source: Saudi Journal of Biological Sciences - April 10, 2019 Category: Biology Source Type: research

The effects of cerebral curvature on cortical spreading depression
In this study a large scale numerical NVC model of multiple NVUs is coupled to a vascular tree simulating a two-dimensional cerebral tissue slice. This model is extended with a spatial Gaussian curvature mapping that can simulate the highly folded nature of the human cortex. For a flat surface comparable to a lissencephalic cortex the model can simulate propagating waves of high extracellular K+ travelling radially outwards from a stimulated area at approximately 6.7 mm/min, corresponding well with multiple experimental results. The high K+ concentration induces a corresponding wave of vasoconstriction (with decreased bloo...
Source: Journal of Theoretical Biology - April 9, 2019 Category: Biology Source Type: research

TIGAR alleviates ischemia/reperfusion-induced autophagy and ischemic brain injury.
In conclusion, our current data suggest that TIGAR protected against neuronal injury partly through inhibiting autophagy by regulating the mTOR-S6KP70 signaling pathway. PMID: 30978385 [PubMed - as supplied by publisher]
Source: Free Radical Biology and Medicine - April 8, 2019 Category: Biology Authors: Zhang DM, Zhang T, Wang MM, Wang XX, Qin YY, Wu J, Han R, Sheng R, Wang Y, Chen Z, Han F, Ding Y, Li M, Qin ZH Tags: Free Radic Biol Med Source Type: research

Contrasting Metatrochal Behavior of Mollusc and Annelid Larvae and the Regulation of Feeding While Swimming.
Abstract Molluscan veliger larvae and some annelid larvae capture particulate food between a preoral prototrochal band of long cilia that create a current for both swimming and feeding and a postoral metatrochal band of shorter cilia that beat toward the prototroch. Larvae encountering satiating or noxious particles must somehow swim without capturing particles or else reject large numbers of captured particles. Because high rates of particle capture are inferred to depend on the beat of both ciliary bands, arrest of the metatroch could be one way to swim while reducing captures. Larvae in eight families of anneli...
Source: The Biological Bulletin - March 31, 2019 Category: Biology Authors: Strathmann RR, Brante A, Oyarzun FX Tags: Biol Bull Source Type: research

Contraction of atrial smooth muscle reduces cardiac output in perfused turtle hearts RESEARCH ARTICLE
William Joyce, Michael Axelsson, and Tobias Wang Unusual undulations in resting tension (tonus waves) were described in isolated atria from freshwater turtles more than a century ago. These tonus waves were soon after married with the histological demonstration of a rich layer of smooth muscle on the luminal side of the atrial wall. Research thereafter waned and the functional significance of this smooth muscle has remained obscure. Here, we provide evidence that contraction of the smooth muscle in the atria may be able to change cardiac output in turtle hearts. In in situ perfused hearts of the red-eared slider turtle (T...
Source: Journal of Experimental Biology - March 20, 2019 Category: Biology Authors: Joyce, W., Axelsson, M., Wang, T. Tags: RESEARCH ARTICLE Source Type: research

Shark lessons for stroke and heart attack victims INSIDE JEB
Kathryn Knight
Source: Journal of Experimental Biology - March 20, 2019 Category: Biology Authors: Knight, K. Tags: INSIDE JEB Source Type: research