Query: stroke

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A population stereotaxic positron emission tomography brain template for the macaque and its application to ischemic model
ConclusionWe have constructed a stereotaxic template set of macaque brain named HJT, which standardizes macaque neuroimaging data analysis, supports novel radiotracer development and facilitates translational neuro-disorders research.
Source: NeuroImage - October 13, 2019 Category: Neuroscience Source Type: research

Modulation of the autonomic nervous system through mind and body practices as a treatment for atrial fibrillation.
Authors: Bashir MU, Bhagra A, Kapa S, McLeod CJ Abstract Atrial fibrillation is the most common symptomatic arrhythmia that is associated with stroke. Contemporary management of the disease is focused on anticoagulation to prevent stroke, coupled with catheter ablation to limit symptoms and prevent deleterious cardiac remodeling. Emerging data highlights the importance of lifestyle modification by managing sleep apnea, increasing physical activity, and weight loss. There is significant data that supports a link between the autonomic nervous system, arrhythmia development, and atrial fibrillation therapy. It is like...
Source: Reviews in Cardiovascular Medicine - October 13, 2019 Category: Cardiology Tags: Rev Cardiovasc Med Source Type: research

Active nonlinear control of a stroke limited inertial actuator: Theory and experiment
Publication date: Available online 12 October 2019Source: Journal of Sound and VibrationAuthor(s): M. Dal Borgo, M. Ghandchi Tehrani, S.J. ElliottAbstractThis paper presents a theoretical and experimental study of a stroke limited inertial actuator when used for active vibration control. The active control system under investigation consists of the inertial actuator attached to a flexible structure, a collocated vibration sensor and a velocity feedback controller (VFC). Controlling low frequency motions or large amplitude vibrations requires a very long stroke for the proof mass. However, a physical limitation of inertial ...
Source: Journal of Sound and Vibration - October 13, 2019 Category: Physics Source Type: research

Take AARP's Newest Weekly News Quiz
{ "imageBrowse": "", "imageCaption": "", "imageCredit": "", "question": " ... Recent research found that a substantial loss of income can raise the risk of heart attack and stroke. ... Is the follo...
Source: AARP.org News - October 13, 2019 Category: American Health Source Type: news

The potential of drug repurposing combined with reperfusion therapy in cerebral ischemic stroke: A supplementary strategy to endovascular thrombectomy
Publication date: Available online 11 October 2019Source: Life SciencesAuthor(s): Jenq-Lin Yang, Yun-Ru Yang, Shang-Der ChenAbstractStroke is the major cause of adult disability and the second or third leading cause of death in developed countries. The treatment options for stroke (thrombolysis or thrombectomy) are restricted to a small subset of patients with acute ischemic stroke because of the limited time for an efficacious response and the strict criteria applied to minimize the risk of cerebral hemorrhage. Attempts to develop new treatments, such as neuroprotectants, for acute ischemic stroke have been costly and tim...
Source: Life Sciences - October 13, 2019 Category: Biology Source Type: research

β-Caryophyllene protects against ischemic stroke by promoting polarization of microglia toward M2 phenotype via the TLR4 pathway
The objective of the study was to determine whether β-caryophyllene (BCP) exerts a neuroprotective effect in cerebral ischemia-reperfusion (I/R) injury by inhibiting microglial activation and modulating their polarization via the TLR4 pathway.Main methodsWild-type (WT) and TLR4 knockout (KO) C57BL/6J mice were subjected to cerebral I/R injury and neurologic dysfunction, cerebral infarct volume, brain edema, microglia activation and polarization, and TLR4 expression were determined. In vitro, primary microglia were stimulated with LPS and IFN-γ or IL-4 to induce polarization of microglia toward M1 or M2 phenotypes.Key fin...
Source: Life Sciences - October 13, 2019 Category: Biology Source Type: research

Ectopic TWEAKR expression in type I fiber of stroke-prone spontaneously hypertensive rats is related to slow muscle-specific hypotrophy
In this study, we aimed to investigate the pathophysiological characteristics of muscle hypotrophy in SHRSP to determine the therapeutic target molecule(s).Main methodsThe difference in skeletal muscles in the lower leg between WKY and SHRSP was evaluated mainly through weight/tibial length, histological, gene expression, and protein expression analyses.Key findingsSHRSP had a significantly lower weight/tibial length in soleus and gastrocnemius, but not in plantaris and tibialis anterior, indicating that muscles consisting of a relatively high amount of slow muscle fiber were affected. This result was confirmed by the hist...
Source: Life Sciences - October 13, 2019 Category: Biology Source Type: research

The correlation between feeding intolerance and poor prognosis of patients with severe neurological conditions: a case-control study.
Conclusion: The incidence of early FI in stroke patients is correlated with a poor prognosis. PMID: 31601136 [PubMed - as supplied by publisher]
Source: Expert Review of Neurotherapeutics - October 12, 2019 Category: Neurology Tags: Expert Rev Neurother Source Type: research

Safety and efficacy of self-expandable Evolut R vs. balloon-expandable Sapien 3 valves for transcatheter aortic valve implantation: A systematic review and meta-analysis.
Authors: He C, Xiao L, Liu J Abstract The aim of this study was to systematically search literature and conduct a meta-analysis comparing the clinical efficacy and safety of Evolut R and Sapien 3 valves for transcatheter aortic valve implantation (TAVI). The PubMed, Biomed Central, Scopus, Cochrane library and Google scholar databases were searched for articles published up to June, 2019. A total of 5 studies were included. In total, 795 patients underwent TAVI with Evolut R, while 665 patients received the Sapien 3 valve in the included studies. Overall device success with Evolut R was 95.7% and with Sapien 3 was ...
Source: Experimental and Therapeutic Medicine - October 12, 2019 Category: General Medicine Tags: Exp Ther Med Source Type: research

Resveratrol ameliorates brain injury via the TGF- β-mediated ERK signaling pathway in a rat model of cerebral hemorrhage.
In conclusion, these results indicate that resveratrol decreases ischemia/reperfusion-induced neuronal apoptosis by downregulating the TGF-β-mediated ERK pathway in a rat model of cerebral hemorrhage and may serve as a potential agent for the treatment of cerebral hemorrhage. PMID: 31602214 [PubMed]
Source: Experimental and Therapeutic Medicine - October 12, 2019 Category: General Medicine Tags: Exp Ther Med Source Type: research

Activation of the primary motor cortex using fully-implanted electrical sciatic nerve stimulation.
Authors: Lv X, Tang R, Gao Z, Hu D, Li G, Lang Y, He J Abstract Functional degradation of the motor cortex usually results from brain injury, stroke, limb amputation, aging or other diseases. Currently, there are no ideal means of treatment, other than medication and sports rehabilitation. The present study investigated whether electrical stimulation of the sciatic nerve can activate the motor-related area of the brain. The study is based on a self-developed fully implantable nerve electrical stimulator and a self-developed multi-channel electroencephalogram (EEG) electrode array. The sciatic nerves of Sprague-Dawl...
Source: Experimental and Therapeutic Medicine - October 12, 2019 Category: General Medicine Tags: Exp Ther Med Source Type: research

Comparative occurrence of ischemic stroke with the rhythm versus rate control strategy in a national prospective cohort of atrial fibrillation.
Conclusions: The rhythm control strategy demonstrated a beneficial effect to lower the risk of ischemic stroke during a 1-year follow-up compared to the rate control strategy. PMID: 31597907 [PubMed - as supplied by publisher]
Source: The Korean Journal of Internal Medicine - October 12, 2019 Category: Internal Medicine Authors: Kim JG, Lee YS, Kang KW, Choi EK, Cha MJ, Lee JM, Kim JB, Park J, Park JK, Kim TH, Uhm JS, Shim J, Kim J, Park H, Kim C, Joung B Tags: Korean J Intern Med Source Type: research

Effectiveness of the new generation transcatheter aortic valve in the real life studies. Review and meta-analysis.
CONCLUSIONS: The results of the meta-analysis show that: (1) ACURATE neo was associated with significantly less new permanent pacemaker implantation than SAPIEN 3 and EVOLUT R/PRO; (2) SAPIEN 3 had significantly lower occurrence of moderate/severe valvular leak than ACURATE neo. PMID: 31599427 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - October 12, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Coiled artificial muscles based on uhmwpe with large muscle stroke
Publication date: Available online 11 October 2019Source: Materials Today CommunicationsAuthor(s): A.V. Maksimkin, I.I. Larin, D.I. Chukov, M.Yu. Zadorozhnyy, T. Dayyoub, V.Yu. Zadorozhnyy, F. Spieckermann, V. SoprunyukAbstractThermal sensitive сoiled artificial muscles with a large muscle stroke (87 %) based on oriented ultrahigh molecular weight polyethylene fibers were created. The storage modulus and the recovery stress were used as indicators to determine the optimal conditions for the orientation process of the UHMWPE fibers. The working mechanism of the coiled artificial muscles was discussed in terms of a one-way ...
Source: Materials Today Communications - October 12, 2019 Category: Materials Science Source Type: research

Poor Glycemic Control May Up Risk for Stroke, Death in T2DM
FRIDAY, Oct. 11, 2019 -- Poor glycemic control is associated with increased risks for stroke and death among patients with type 2 diabetes, according to a study published online Oct. 1 in Diabetes, Obesity and Metabolism. Alexander Zabala, M.D.,...
Source: Drugs.com - Pharma News - October 11, 2019 Category: Pharmaceuticals Source Type: news

Effect of Acute Stroke Care Regionalization on Intravenous Alteplase Use in Two Urban Counties.
Conclusions: Our findings suggest that greater post-regionalization improvements in San Mateo County contributed to significantly better county-level thrombolysis use than Santa Clara County. PMID: 31599705 [PubMed - as supplied by publisher]
Source: Prehospital Emergency Care - October 11, 2019 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research

Efficacy and Safety of NaoShuanTong Capsule in the Treatment of Ischemic Stroke: A Meta-Analysis
Conclusions: The results of this meta-analysis showed that NSTC exhibits efficacy in the treatment of cerebral infarction. NSTC can improve the overall response rate and neurological function, increase blood adiponectin, reduce neurological deficits, and decrease atherosclerotic plaque area.
Source: Frontiers in Pharmacology - October 11, 2019 Category: Drugs & Pharmacology Source Type: research

A Cross-Sectional Analysis of Differences in Physical Activity Levels between Stroke Belt and Non-Stroke Belt US Adults
Background: The Stroke Belt is a region of the United States with elevated stroke incidence and prevalence of stroke risk factors. Physical inactivity is an important stroke risk factor, but little is known about whether current physical activity levels differ between Stroke Belt and non-Stroke Belt states. In this nationally representative study, we determined whether unadjusted and adjusted physical activity levels differ between the Stroke Belt region and the rest of the United States. Methods: Using 2017 Behavioral Risk Factor Surveillance System data, we conducted bivariate analyses to obtain unadjusted physical activ...
Source: Journal of Stroke and Cerebrovascular Diseases - October 11, 2019 Category: Neurology Authors: Phoebe Tran, Lam Tran, Liem Tran Source Type: research

Race-Ethnic Disparities in 30-Day Readmission After Stroke Among Medicare Beneficiaries in the Florida Stroke Registry
Objective: To examine racial/ethnic disparities in 30-day all-cause readmission after stroke. Methods: Thirty-day all-cause readmission was compared by race/ethnicity among Medicare fee-for-service beneficiaries discharged for ischemic stroke from hospitals in the Florida Stroke Registry from 2010 to 2013. We fit a Cox proportional hazards model that censored for death and adjusted for age, sex, length of stay, discharge home, and comorbidities to assess racial/ethnic differences in readmission.
Source: Journal of Stroke and Cerebrovascular Diseases - October 11, 2019 Category: Neurology Authors: Hannah Gardener, Erica C. Leifheit, Judith H. Lichtman, Kefeng Wang, Yun Wang, Carolina M. Gutierrez, Maria A. Ciliberti-Vargas, Chuanhui Dong, Mary Robichaux, Jose G. Romano, Ralph L. Sacco, Tatjana Rundek, FL-PR CReSD Investigators and Collaborators Source Type: research

Very Early MoCA Can Predict Functional Dependence at 3 Months After Stroke: A Longitudinal, Cohort Study
Conclusion: Cognitive function assessed with the MoCA within 36–48 h after stroke could predict functional dependence 3 months later. The participants with MoCA scores ≤23 for impaired cognition were more likely to be functionally dependent.
Source: Frontiers in Neurology - October 11, 2019 Category: Neurology Source Type: research

Direct Admission vs. Secondary Transfer to a  Comprehensive Stroke Center for Thrombectomy
ConclusionThese results confirm prior studies stating that DA to a  comprehensive stroke center leads to better outcome compared to ST in stroke patients undergoing thrombectomy.
Source: Klinische Neuroradiologie - October 11, 2019 Category: Radiology Source Type: research

A brain-stellate ganglion-atrium network regulates atrial fibrillation vulnerability through macrophages in acute stroke
Publication date: Available online 9 October 2019Source: Life SciencesAuthor(s): Youcheng Wang, Xiaoxing Xiong, Baojun Xie, Jia Liu, Mei Yang, Junkui Yin, Liuliu Zi, Xi Wang, Yanhong Tang, Congxin Huang, Haixia Fu, Qingyan ZhaoAbstractAimsNew-onset atrial fibrillation (AF) is frequently observed following acute stroke. The aim of this study was to investigate the effects of the brain-stellate ganglion-atrium network on AF vulnerability in a canine model with acute middle cerebral artery occlusion (MCAO).Materials and methodsTwenty-six dogs were randomly divided into the sham-operated group (n = 6), acute stroke (AS) gr...
Source: Life Sciences - October 10, 2019 Category: Biology Source Type: research

Mirror feedback assisted recovery from hemiparesis following stroke In Reply to Morkisch et al.: How to perform mirror therapy after stroke? Evidence from a meta-analysis.
Authors: Ramachandran VS, Rogers-Ramachandran D Abstract 1 out of 6 people worldwide will have suffered a stroke in their lifetime, 1/3rd of whom will die. Of the 2/3rd who survive, half will be permanently disabled (World Stroke Organization). Given these alarming statistics, it's not surprising that tremendous of amounts of time, resources and funding have been devoted towards research into stroke rehab. In view of this, simple, easy-to-implement procedures are highly sought after. One such procedure is the use of visual feedback conveyed by a mirror, which seems to reactivate some dormant pathways in patients wh...
Source: Restorative Neurology and Neuroscience - October 10, 2019 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

The effect of neuromuscular electrical stimulation with different electrode positions on swallowing in stroke patients with oropharyngeal dysphagia: A randomized trial.
CONCLUSIONS: Altogether, these data demonstrate that 2 types of NMES placements have a similar effect on improving swallowing function and oral diet intake in patients with dysphagia. PMID: 31594198 [PubMed - as supplied by publisher]
Source: Journal of Back and Musculoskeletal Rehabilitation - October 10, 2019 Category: Orthopaedics Tags: J Back Musculoskelet Rehabil Source Type: research

Gait training with auditory feedback improves trunk control, muscle activation and dynamic balance in patients with hemiparetic stroke: A randomized controlled pilot study.
CONCLUSION: Our findings indicate that gait training with auditory feedback was beneficial for improving trunk control and muscle activation in patients with hemiparetic stroke. PMID: 31594193 [PubMed - as supplied by publisher]
Source: Journal of Back and Musculoskeletal Rehabilitation - October 10, 2019 Category: Orthopaedics Tags: J Back Musculoskelet Rehabil Source Type: research

Recurrent Embolic Stroke Associated with Long-Latency Relapsing Cardiac Myxoma.
Authors: Guk HS, Lee S, Jeong HB, Ju W, Choi JS, Lee YS PMID: 31591856 [PubMed]
Source: Journal of Clinical Neurology - October 10, 2019 Category: Neurology Tags: J Clin Neurol Source Type: research

Long-Term Outcomes of Real-World Korean Patients with Atrial-Fibrillation-Related Stroke and Severely Decreased Ejection Fraction.
CONCLUSIONS: Severe LV systolic dysfunction could be a determinant of long-term outcomes in AF-related stroke. PMID: 31591844 [PubMed]
Source: Journal of Clinical Neurology - October 10, 2019 Category: Neurology Tags: J Clin Neurol Source Type: research

The stroke exercise preference inventory is feasible to use in a community rehabilitation setting.
Abstract Exploring exercise preferences may help people to adhere to exercise programs by promoting customized programs to suit the person's choices and concerns. We investigated if the Stroke Exercise Preference Inventory, a questionnaire designed to explore stroke survivors' preferences for exercise and potential barriers, was feasible to use, and whether it assisted physiotherapists to design ongoing exercise programs in a mixed diagnostic convenience sample attending community rehabilitation. Physiotherapy staff interviewed 42 participants, and sought feedback about the questionnaire. Participant responses for...
Source: Physiotherapy Theory and Practice - October 10, 2019 Category: Physiotherapy Authors: Blennerhassett JM, Cooper T, Logan A, Cumming TB Tags: Physiother Theory Pract Source Type: research

Imaging Clot Characteristics in Stroke and its Possible Implication on Treatment
AbstractIschemic cerebral stroke is an increasingly treatable entity due to the recent developments in intravascular clot extraction, with recent research indicating that the efficacy of the chosen thrombectomy device may be affected by the composition of the occluding clot. This literature review summarizes the results from analytical clot imaging studies, and in vitro and in vivo thrombectomies, to assess whether the choice of thrombectomy device can be optimized to the composition of the occluding clot. The literature has shown that the composition of the clot impacts its mechanical properties and interactions with the ...
Source: Clinical Neuroradiology - October 10, 2019 Category: Neurology Source Type: research

Stroke and Systemic Embolism and other Adverse Outcomes of Heart Failure with Preserved and Reduced Ejection Fraction in Patients with Atrial Fibrillation (From the COmparison study of Drugs for symptom control and complication prEvention of Atrial Fibrillation CODE-AF)
It is unknown whether heart failure (HF) with preserved ejection fraction (HFpEF) and HF with reduced ejection fraction (HFrEF) carry a similar risk of stroke or systemic embolism (SE) and other outcomes in patients with non-valvular atrial fibrillation (AF). A prospective, multicenter outpatient registry with echocardiographic data which enrolled 10,589 patients from June 2016 to May 2019 was analyzed. In this registry, 935 (8.8%) patients had HF, and the proportions of patients with HFpEF and HFrEF were 43.2% and 56.8%, respectively.
Source: The American Journal of Cardiology - October 10, 2019 Category: Cardiology Authors: Seyong Chung, Tae-Hoon Kim, Jae-Sun Uhm, Myung-Jin Cha, Jung-Myung Lee, Junbeom Park, Jin-Kyu Park, Ki-Woon Kang, Jun Kim, Hyung Wook Park, Eue-Keun Choi, Jin-Bae Kim, Chang-Soo Kim, Young Soo Lee, Jaemin Shim, Boyoung Joung Source Type: research

Embolic Stroke of Undetermined Source in Saudi Arabia: Prevalence, Patient Characteristics, and Outcomes
Background: Embolic stroke of undetermined source (ESUS) is a newly introduced clinical construct to better characterize cryptogenic stroke. It is associated with considerable morbidity and mortality and a high recurrence rate. It has not previously been investigated in Saudi stroke patients. We aimed to conduct a descriptive analysis of ESUS in Saudi Arabia, including its frequency among patients with acute stroke, characteristics, and outcomes. Methods: We reviewed all ischemic stroke patients admitted to the stroke unit at King Abdulaziz Medical City-Riyadh, Saudi Arabia, from February 2016 to July 2018.
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2019 Category: Neurology Authors: Ali M. Al Khathaami, Bayan Al Bdah, Abdulmjeed Alnosair, Rayan Alrebdi, Shorug Alwayili, Sulaiman Alhamzah, Abdulkarim Al Turki, Nasser Alotaibi Source Type: research

Even Faster Door-to-Alteplase Times and Associated Outcomes in Acute Ischemic Stroke
We report a single-center, retrospective assessment of the safety and efficacy of alteplase treatment within 45 minutes. Methods: Five hundred and eighty-six patients were treated with alteplase in our emergency departments (EDs) between January 2014 and October 2016; 368 patients were included for analysis.
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2019 Category: Neurology Authors: Sarah Jung, Jamie M. Rosini, Jason T. Nomura, Richard J. Caplan, Jonathan Raser-Schramm Source Type: research

Notification Strategy and Predictors of Outcome in Stroke Ineligible for Reperfusion Therapies
Conclusions: EMS notification is influenced by AF, stroke severity, psychiatric disease, aphasia, and residence type. Early disability depends on age, the type and severity of the stroke, and pre-stroke mRS. Predictors of disability at 1 year after stroke are age, stoke severity, mRS at discharge, and recurrent ischemic stroke. Higher NIHSS and older age are associated with higher case fatality. In patients ineligible for recanalization, EMS notification had no significant effect on outcome, regarding both disability and survival.
Source: Frontiers in Neurology - October 10, 2019 Category: Neurology Source Type: research

Embodiment and Presence in Virtual Reality After Stroke. A Comparative Study With Healthy Subjects
This study determined and compared the sense of embodiment and presence elicited by a virtual environment under different perspectives and levels of immersion in healthy subjects and individuals with stroke. Forty-six healthy subjects and 32 individuals with stroke embodied a gender-matched neutral avatar in a virtual environment that was displayed in a first-person perspective with a head-mounted display and in a third-person perspective with a screen, and the participants were asked to interact in a virtual task for 10 min under each condition in counterbalanced order, and to complete two questionnaires about the sense o...
Source: Frontiers in Neurology - October 10, 2019 Category: Neurology Source Type: research

Underrated Cause of Hypoxemia and Stroke in Patient with Cirrhosis
The subpleural arteriovenous shunts that are hallmarks of hepatopulmonary syndrome may cause stroke. Published on 2019-10-09 08:03:12
Source: Journal of the Belgian Society of Radiology - October 9, 2019 Category: Radiology Source Type: research

Stroke rates continue decline in the U.S.
(Reuters Health) - Rates of stroke among U.S. adults over age 65 have steadily decreased over the past 30 years, according to a study that tracked participants from the 1980s through December 2017.
Source: Reuters: Health - October 9, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Medical News Today: Having a dog may boost survival after a heart attack or stroke
Two new studies show that owning a dog significantly reduces people's risk of death following a heart attack or stroke, as well as death from any cause.
Source: Health News from Medical News Today - October 9, 2019 Category: Consumer Health News Tags: Veterinary Source Type: news

Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in people with stroke or transient ischaemic attack.
CONCLUSIONS: Peroxisome proliferator-activated receptor gamma agonists probably reduce recurrent stroke and total events of cardiovascular death, non-fatal myocardial infarction or non-fatal stroke, and may improve insulin sensitivity and the stabilisation of carotid plaques. Their effects on adverse events are uncertain. Our conclusions should be interpreted with caution considering the small number and the quality of the included studies. Further well-designed, double-blind RCTs with large samples are required to assess the efficacy and safety of PPAR-γ agonists in the secondary prevention of stroke and related vascular...
Source: Cochrane Database of Systematic Reviews - October 9, 2019 Category: General Medicine Authors: Liu J, Wang LN Tags: Cochrane Database Syst Rev Source Type: research

Comfortably numb? Experiences of people with stroke and lower limb sensation deficits: impact and solutions.
Conclusions: Sensory deficit contributes to effects upon physical function, mobility and activity. Clinical outcome measures need to capture the emotional, psychological and social impacts of sensory deficit. Participants demonstrated a resilience and resourcefulness through adaption in daily living and self-management of footwear. The participants focus on footwear provides the opportunity to develop discrete and non-burdensome vibrotactile insoles for this patient group. IMPLICATIONS FOR REHABILITATION Sensory deficits are wide ranging and varied and are not distinct from motor deficits though contribute to the overall e...
Source: Disability and Rehabilitation. Assistive Technology. - October 9, 2019 Category: Rehabilitation Authors: Luckie H, Hollands K, Williamson T, Nester C, Williams A Tags: Disabil Rehabil Assist Technol Source Type: research

Aerobic Exercise Recommendations to Optimize Best Practices in Care After Stroke: AEROBICS 2019 Update.
The objective of this project was to update AEROBICS 2013 using the highest quality of evidence currently available. The first step was to conduct a comprehensive review of literature from 2012-2018 related to aerobic exercise poststroke. A working group of the original consensus panel members drafted revisions based on synthesis. An iterative process was used to achieve agreement among all panel members. Final revisions included: (1) addition of 115 new references to replace or augment those in the original AEROBICS document, (2) rewording of the original recommendations and supporting material, and (3) addition of 2 new ...
Source: Physical Therapy - October 9, 2019 Category: Physiotherapy Authors: MacKay-Lyons M, Billinger SA, Eng JJ, Dromerick A, Giacomantonio N, Hafer-Macko C, Macko R, Nguyen E, Prior P, Suskin N, Tang A, Thornton M, Unsworth K Tags: Phys Ther Source Type: research

Allometric versus ratiometric normalization of left ventricular stroke volume by Doppler-echocardiography for outcome prediction in severe aortic stenosis with preserved ejection fraction
Appropriate normalization methods to scale Doppler-derived stroke volume (SV) to body size in patients with aortic stenosis (AS) are poorly defined and reference values are lacking. We aim to establish reference values of normalized SV in adults, and to compare the prognostic value of SV normalized by different methods in AS patients.
Source: International Journal of Cardiology - October 9, 2019 Category: Cardiology Authors: Dan Rusinaru, Ernst R. Rietzschel, Yohann Bohbot, Marc L. De Buyzere, Otilia Buiciuc, Sylvestre Mar échaux, Thierry C. Gillebert, Christophe Tribouilloy Source Type: research

Prevalence of Modifiable Risk Factors and Relation to Stroke and Death in Patients with Atrial Fibrillation: A Report from the China Atrial Fibrillation Registry (China ‐AF) Study
ConclusionsMaintenance of well ‐controlled risk factors may substantially lower the risk of death and ischemic stroke in AF patients.This article is protected by copyright. All rights reserved.
Source: Journal of Cardiovascular Electrophysiology - October 9, 2019 Category: Cardiology Authors: Chao Jiang, Di ‐Hui Lan, Xin Du, Yan‐Ping Geng, San‐Shuai Chang, Danni Zheng, Jin‐Bo Chen, Rong‐Hui Yu, Cai‐Hua Sang, De‐Yong Long, Ri‐Bo Tang, Ying‐Chun Zhou, Yan Min, Yuan Lu, Jian‐Zeng Dong, Gregory Y.H. Lip, Chang Tags: ORIGINAL ‐ CLINICAL Source Type: research

Variation in Clinical Presentations and Outcomes of Heat Stroke Victims in the Mass-Casualty Setting
Immigrants crossing the Southern U.S. border are particularly susceptible to heat illness. We review 3 patients from a heat-related mass-casualty incident with variations in heat stroke presentation, course, and outcome.
Source: The Journal of Emergency Medicine - October 9, 2019 Category: Emergency Medicine Authors: Judith M. Knoll, Lorelle R. Knight, Devin Quiroz, Shyam M. Popat, Thomas G. Pederson, Nicholas Morton-Gonzaba Tags: Clinical Communications: Adult Source Type: research

Prehospital and Emergency Department-Focused Mission Protocol Improves Thrombolysis Metrics for Suspected Acute Stroke Patients
Background: The Mission Protocol was implemented in 2017 to expedite stroke evaluation and reduce door-to-needle (DTN) times at Zuckerberg San Francisco General Hospital. The key system changes were team-based evaluation of suspected stroke patients at ambulance entrance by an Emergency Department (ED) physician, ED nurse, and neurologist and immediate emergency medical service (EMS) provider transport of patients to CT. Methods: Patients were eligible for a Mission Protocol prehospital stroke activation if an EMS provider found a positive Cincinnati Prehospital Stroke Scale and a last known normal time within 6 hours.
Source: Journal of Stroke and Cerebrovascular Diseases - October 9, 2019 Category: Neurology Authors: Debbie Y. Madhok, Kevin J. Keenan, Sara B. Cole, Christine Martin, J. Claude Hemphill Source Type: research

Coronary Artery Disease in Patients with Ischemic Stroke and TIA
Ischemic stroke (IS) and coronary artery disease (CAD) share common risk factors and one may be the harbinger of the other. We aimed to study prevalence of symptomatic and asymptomatic CAD in a cohort of consecutive patients with IS and assess its relationship with intracranial and extracranial large artery cerebrovascular disease (LAD).
Source: Journal of Stroke and Cerebrovascular Diseases - October 9, 2019 Category: Neurology Authors: Rohit Bhatia, Gautam Sharma, Chetan Patel, Ajay Garg, Ambuj Roy, Prerna Bali, Nishita Singh, Pranjal Sisodia, Vishnubhatla Sreenivas, M.V. Padma Srivastava, Kameshwar Prasad Source Type: research

Response to “Potential Clinical and Radiographic Horizontal Gaze Deviation an Early Sign of Stroke”
We would like to thank Dr. Kattah for commenting on our article “Degree of Conjugate Gaze Deviation on CT Predicts Proximal Vessel Occlusion and May Expedite Endovascular Therapy”.
Source: Journal of Stroke and Cerebrovascular Diseases - October 9, 2019 Category: Neurology Authors: Nan N. Jiang, Crystal Fong, Demetrios J. Sahlas, Sandra Monteiro, Ramiro Larrazabal Tags: Letter to the Editor Source Type: research

Determinants of dysphagia following stroke
Conclusions:Among 15 factors evaluated, age, type of lesion and Brunnstrom ’s stages showed a significant association with the severity of dysphagia following stroke. This study advocates early dysphagia management for elderly patients with high Brunnstrom’s grading, for those who are not expected to spontaneously recover following stroke, and for earlier and better co mmunity rehabilitation. [Ethiop.J. Health Dev. 2019; 33(3):147-152]Key words: Post-stroke dysphagia, Brunnstrom ’s stages, dysphagia risk factors.
Source: Ethiopian Journal of Health Development - October 8, 2019 Category: African Health Source Type: research

Anodal transcranial direct current stimulation with monopolar pulses improves limb use after stroke by enhancing inter-hemispheric coherence.
Abstract Post-stroke neurological deficits, such as sensorimotor impairments, are often permanent and a leading cause of disability. Stroke is also associated with changes in neuronal synchrony among different brain areas. Multiple studies demonstrated that non-invasive brain stimulation, such as transcranial direct current stimulation (tDCS), enhances the efficacy of existing rehabilitative therapies. We hypothesized that the therapeutic effects of tDCS could be due to its influence on neuronal synchrony. To study this, we recorded local field potentials in rats treated with anodal tDCS (a-tDCS) after unilateral ...
Source: Acta Neurobiologiae Experimentalis - October 8, 2019 Category: Neurology Authors: Schjetnan AG, Gidyk DC, Metz GA, Luczak A Tags: Acta Neurobiol Exp (Wars) Source Type: research

Diagnostic Impact of Intracranial Vessel Wall MRI in 205 Patients with Ischemic Stroke or TIA ADULT BRAIN
CONCLUSIONS: When vessel wall MR imaging is performed to clarify the etiology of a stroke or TIA, it frequently alters the etiologic classification. This is important because the etiologic classification is the basis for therapeutic decision-making.
Source: American Journal of Neuroradiology - October 8, 2019 Category: Radiology Authors: Schaafsma, J. D., Rawal, S., Coutinho, J. M., Rasheedi, J., Mikulis, D. J., Jaigobin, C., Silver, F. L., Mandell, D. M. Tags: ADULT BRAIN Source Type: research

End-user and clinician perspectives on the viability of wearable functional electrical stimulation garments after stroke and spinal cord injury.
Conclusions: The insights obtained from end-users and clinicians provide guidelines to optimize the development of novel FES-garments, and strategies for bringing the device to the market. The themes identified can serve to inform other rehabilitation and assistive technology developers with processes and ideas on how to meet these groups' needs. IMPLICATIONS FOR REHABILITATION Participants with neurological paralysis have interest and critical views on new rehabilitation and assistive technology, and the repercussions of using new technologies to address their function, health and wellbeing. The FES-garment design present...
Source: Disability and Rehabilitation. Assistive Technology. - October 8, 2019 Category: Rehabilitation Authors: Moineau B, Myers M, Ali SS, Popovic MR, Hitzig SL Tags: Disabil Rehabil Assist Technol Source Type: research