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Management of Acute Cerebral Infarction by Intravenous Thrombolysis with Recombinant T Cell Receptor and Plasminogen Activator and Association of Emergency Nursing Route in the Prognosis
In this study, 100 patients were randomly selected that were equally divided into experimental and control groups. The period of hospital admission, the results of the Montreal Cognitive Assessment (MoCA) and the Mini-mental State Examination (MMSE), the results of the Glasgow Outcome Scale (GOS), and the results of the Activities of Daily Living were all analysed before and after the intervention.. Both the amount of time it took to get a diagnosis after being admitted and the amount of time it took to receive specialised therapy after receiving a diagnosis were significantly reduced in the observation group (both P value...
Source: Cellular and Molecular Biology - September 16, 2023 Category: Molecular Biology Authors: None Yuqi Liu None Chengyong Wang None Yuanpeng Han Source Type: research
Association of psoriasis and stroke in end-stage renal disease patients
CONCLUSIONS: Contrary to prior research in the general population, psoriasis in ESRD patients was not associated with the risk of stroke after controlling for various demographic and clinical parameters. Our finding emphasizes the importance of controlling for a variety of factors in population studies examining associations of diseases and risk factors.PMID:37716600 | DOI:10.1016/j.amjms.2023.09.014
Source: The American Journal of the Medical Sciences - September 16, 2023 Category: General Medicine Authors: Naomi Siddiquee Jennifer L Waller Stephanie L Baer Azeem Mohammed Sarah Tran Sandeep Padala Lufei Young Mufaddal Kheda Wendy B Bollag Source Type: research
Morphological characteristics of brain aneurysms among age groups
CONCLUSIONS: Younger patients have small unruptured and ruptured aneurysms, and ruptured aneurysms are mostly located in the MCA and ACOM. Older patients have larger and more irregular unruptured aneurysms, and ruptured aneurysms are mostly located in the PCOM and ACOM. An irregular morphology increases the risk of rupture in all age groups.PMID:37715650 | DOI:10.1177/15910199231201520
Source: Interventional Neuroradiology - September 16, 2023 Category: Radiology Authors: Sebastian Sanchez Muhammed Amir Essibayi Meredith Hickerson Diego J Ojeda Sami Al Kasab Shinichi Yoshimura Pascal M Jabbour Justin Mascitelli Michael R Levitt Hugo H Cuellar-Saenz Waleed Brinjikji Alejandro M Spiotta Amir Shaban Edgar A Samaniego Source Type: research
CircNCOA4 knockdown attenuates OGD-induced neuron injury through miR-338-5p/PDE4B axis
Exp Brain Res. 2023 Sep 16. doi: 10.1007/s00221-023-06702-w. Online ahead of print.ABSTRACTCircular RNAs (circRNAs) have been revealed to be involved in the pathology of acute ischemic stroke (AIS). Herein, we aimed to study the role and mechanism of circNCOA4 in ischemic stroke. The neuron-like cell line SK-N-SH of the experiment group was cultured in oxygen-glucose deprivation (OGD) condition. Cell viability and apoptosis were evaluated by cell counting kit-8 and flow cytometry. The oxidative damage and endoplasmic reticulum stress (ERS) were analyzed by measuring the production of reactive oxygen species (ROS), malondia...
Source: Experimental Brain Research - September 16, 2023 Category: Neuroscience Authors: Danyang Wang Sai Xiao Xiaoming Li Wenbo Qi Source Type: research
Higher habitual dietary intakes of flavanols and anthocyanins differentially associate with lower incidence of ischemic stroke subtypes-A follow-up analysis
CONCLUSIONS: Higher habitual intakes of flavanols and anthocyanins are differentially associated with lower risk of ischemic stroke from atherosclerosis and/or cardioembolism, but not with other subtypes.PMID:37716608 | DOI:10.1016/j.tjnut.2023.09.011
Source: Atherosclerosis - September 16, 2023 Category: Cardiology Authors: Benjamin H Parmenter Pratik Pokharel Frederik Dalgaard Kevin Murray Aed ín Cassidy Catherine P Bondonno Joshua R Lewis Cecilie Kyr ø Anne Tj ønneland Kim Overvad Jonathan M Hodgson Nicola P Bondonno Source Type: research
Management of Acute Cerebral Infarction by Intravenous Thrombolysis with Recombinant T Cell Receptor and Plasminogen Activator and Association of Emergency Nursing Route in the Prognosis
In this study, 100 patients were randomly selected that were equally divided into experimental and control groups. The period of hospital admission, the results of the Montreal Cognitive Assessment (MoCA) and the Mini-mental State Examination (MMSE), the results of the Glasgow Outcome Scale (GOS), and the results of the Activities of Daily Living were all analysed before and after the intervention.. Both the amount of time it took to get a diagnosis after being admitted and the amount of time it took to receive specialised therapy after receiving a diagnosis were significantly reduced in the observation group (both P value...
Source: Cellular and Molecular Biology - September 16, 2023 Category: Molecular Biology Authors: None Yuqi Liu None Chengyong Wang None Yuanpeng Han Source Type: research
Morphological characteristics of brain aneurysms among age groups
CONCLUSIONS: Younger patients have small unruptured and ruptured aneurysms, and ruptured aneurysms are mostly located in the MCA and ACOM. Older patients have larger and more irregular unruptured aneurysms, and ruptured aneurysms are mostly located in the PCOM and ACOM. An irregular morphology increases the risk of rupture in all age groups.PMID:37715650 | DOI:10.1177/15910199231201520
Source: Interventional Neuroradiology - September 16, 2023 Category: Radiology Authors: Sebastian Sanchez Muhammed Amir Essibayi Meredith Hickerson Diego J Ojeda Sami Al Kasab Shinichi Yoshimura Pascal M Jabbour Justin Mascitelli Michael R Levitt Hugo H Cuellar-Saenz Waleed Brinjikji Alejandro M Spiotta Amir Shaban Edgar A Samaniego Source Type: research
CircNCOA4 knockdown attenuates OGD-induced neuron injury through miR-338-5p/PDE4B axis
Exp Brain Res. 2023 Sep 16. doi: 10.1007/s00221-023-06702-w. Online ahead of print.ABSTRACTCircular RNAs (circRNAs) have been revealed to be involved in the pathology of acute ischemic stroke (AIS). Herein, we aimed to study the role and mechanism of circNCOA4 in ischemic stroke. The neuron-like cell line SK-N-SH of the experiment group was cultured in oxygen-glucose deprivation (OGD) condition. Cell viability and apoptosis were evaluated by cell counting kit-8 and flow cytometry. The oxidative damage and endoplasmic reticulum stress (ERS) were analyzed by measuring the production of reactive oxygen species (ROS), malondia...
Source: Brain Research - September 16, 2023 Category: Neurology Authors: Danyang Wang Sai Xiao Xiaoming Li Wenbo Qi Source Type: research
Morphological characteristics of brain aneurysms among age groups
CONCLUSIONS: Younger patients have small unruptured and ruptured aneurysms, and ruptured aneurysms are mostly located in the MCA and ACOM. Older patients have larger and more irregular unruptured aneurysms, and ruptured aneurysms are mostly located in the PCOM and ACOM. An irregular morphology increases the risk of rupture in all age groups.PMID:37715650 | DOI:10.1177/15910199231201520
Source: Interventional Neuroradiology - September 16, 2023 Category: Radiology Authors: Sebastian Sanchez Muhammed Amir Essibayi Meredith Hickerson Diego J Ojeda Sami Al Kasab Shinichi Yoshimura Pascal M Jabbour Justin Mascitelli Michael R Levitt Hugo H Cuellar-Saenz Waleed Brinjikji Alejandro M Spiotta Amir Shaban Edgar A Samaniego Source Type: research
ISCHEMIC STROKE AND MAJOR BLEEDING WHILE ON DIRECT ORAL ANTICOAGULANTS IN NA ÏVE PATIENTS WITH ATRIAL FIBRILLATION: IMPACT OF RESUMPTION OR DISCONTINUATION OF ANTICOAGULANT TREATMENT. A population-based study.
We assessed the cumulative incidence of recurrent stroke, major bleeding and all-cause mortality associated with restarting antithrombotic treatment, in patients experiencing an anticoagulation-related event (stroke or major bleeding), occurred during anticoagulation therapy for AF.Methods and Results.We performed a retrospective population-based analysis on linked claims data of patients resident in the Veneto Region, treated with DOACs for AF and discharged (2013 −2020) from the hospital for stroke, intracranial haemorrhage (ICH), and major bleeding.
Source: International Journal of Cardiology - September 16, 2023 Category: Cardiology Authors: N. Gennaro, E. Ferroni, M. Zorzi, G. Denas, V. Pengo Source Type: research
Changes in the triglyceride glucose-body mass index estimate the risk of stroke in middle-aged and older Chinese adults: a nationwide prospective cohort study
Stroke was reported to be highly correlated with the triglyceride glucose-body mass index (TyG-BMI). Nevertheless, literature exploring the association between changes in the TyG-BMI and stroke incidence is sc...
Source: Cardiovascular Diabetology - September 16, 2023 Category: Cardiology Authors: Rong-Rui Huo, Lu Zhai, Qian Liao and Xue-Mei You Tags: Research Source Type: research
Prevalence, pattern, and correlates of dyslipidemia in Bangladeshi individuals
Stroke and ischaemic heart disease accounted for the top two causes of death in Bangladesh1. Dyslipidemia is identified as a significant independent modifiable risk factor for cardiovascular diseases (CVDs) that has been strongly connected to the pathophysiology of CVDs2. Dyslipidemia is defined as the presence of abnormal blood concentrations of one or more of the following lipids (fat): total cholesterol (TC), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), and triglycerides (TG)3.
Source: Journal of Clinical Lipidology - September 16, 2023 Category: Lipidology Authors: Md Tauhidul Islam, Md Taqbir Us Samad Talha, Sabit Saad Shafiq, Tapas Mazumder, Rajat Das Gupta, Shahjahan Siraj Tags: Original Research Source Type: research
Brain Pathology in COVID-19: Clinical Manifestations and Potential Mechanisms
AbstractNeurological manifestations of coronavirus disease 2019 (COVID-19) are less noticeable than the respiratory symptoms, but they may be associated with disability and mortality in COVID-19. Even though Omicron caused less severe disease than Delta, the incidence of neurological manifestations is similar. More than 30% of patients experienced “brain fog”, delirium, stroke, and cognitive impairment, and over half of these patients presented abnormal neuroimaging outcomes. In this review, we summarize current advances in the clinical findings of neurological manifestations in COVID-19 patients and compare them with ...
Source: Neuroscience Bulletin - September 16, 2023 Category: Neuroscience Source Type: research
Mouse model hints at pharmacogenomic strategies for stroke treatment in patients possessing a risk variant
Source: Journal of Clinical Investigation - September 15, 2023 Category: Biomedical Science Authors: Douglas E. Vaughan Source Type: research
