Query: stroke

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Stroke Rate Continues to Fall Among Older Americans
Title: Stroke Rate Continues to Fall Among Older AmericansCategory: Health NewsCreated: 10/1/2019 12:00:00 AMLast Editorial Review: 10/2/2019 12:00:00 AM
Source: MedicineNet Heart General - October 2, 2019 Category: Cardiology Source Type: news

Dietary saturated fat intake and risk of stroke: systematic review and dose-response meta-analysis of prospective cohort studies
ConclusionThis meta-analysis further demonstrated that a higher consumption of dietary SFA is associated with a lower risk of stroke, and every 10 grams/day increase in SFA intake is associated with a 6% relative risk reduction in the rate of stroke. Further research is needed to explore the influence of specific SFA types and different macronutrient replacement models of SFA on the stroke risk.
Source: Nutrition, Metabolism and Cardiovascular Diseases - October 2, 2019 Category: Nutrition Source Type: research

Patterns of participation: Facilitating and hindering aspects related to places for activities outside the home after stroke.
Conclusions: Different combinations of aspects facilitated and hindered whether or not participation changed. To support people with stroke in their endeavour to retain or recapture participation, social support is important to consider in relation to transportation, activities and places outside the home. PMID: 31564178 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Occupational Therapy - October 2, 2019 Category: Occupational Health Tags: Scand J Occup Ther Source Type: research

Relationship between pre-stroke physical activity and symptoms of post-stroke anxiety and depression: An observational study.
CONCLUSION: In this group of patients with mild symptoms of emotional distress, it seems that pre-stroke physical activity might be protective against post-stroke depression, but not anxiety. Many patients with mild-to-moderate stroke report being equally active before and after the stroke. PMID: 31565752 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - October 2, 2019 Category: Rehabilitation Tags: J Rehabil Med Source Type: research

Effects of aerobic exercise using cycle ergometry on balance and functional capacity in post-stroke patients: a systematic review and meta-analysis of randomised clinical trials.
Conclusions: The cycle ergometer aerobic exercise did not seem to improve balance or functional capacity in post-stroke patients. IMPLICATIONS FOR REHABILITATION Aerobic exercise with cycle ergometer does not improve balance in patients after chronic stroke, but the results for functional capacity are more promising. Beneficial changes in functional capacity can be seen after 12-4 weeks of training, and are dependent on the initial level of physical fitness of each individual. The use of the cycle-ergometer to improve balance and functional capacity was not superior when compared to conventional physiotherapy; therefore, a...
Source: Disability and Rehabilitation - October 2, 2019 Category: Rehabilitation Authors: Da Campo L, Hauck M, Marcolino MAZ, Pinheiro D, Plentz RDM, Cechetti F Tags: Disabil Rehabil Source Type: research

Possible Biomarker for an Important Yet Neglected Symptom After Stroke  - Metalloproteinase-9 and Post-Stroke Depression.
Possible Biomarker for an Important Yet Neglected Symptom After Stroke - Metalloproteinase-9 and Post-Stroke Depression. Circ J. 2019 Oct 02;: Authors: Wakisaka Y PMID: 31582640 [PubMed - as supplied by publisher]
Source: Circulation Journal - October 2, 2019 Category: Cardiology Authors: Wakisaka Y Tags: Circ J Source Type: research

Stroke Rate Continues to Fall for Older Americans
Starting in the late 1980s, stroke rates among older Americans began to fall -- and the decline shows no signs of stopping, a new study finds.
Source: WebMD Health - October 1, 2019 Category: Consumer Health News Source Type: news

Stroke Rate Continues to Fall Among Older Americans
TUESDAY, Oct. 1, 2019 -- Starting in the late 1980s, stroke rates among older Americans began to fall -- and the decline shows no signs of stopping, a new study finds. The researchers found that between 1987 and 2017, the rate of stroke incidence...
Source: Drugs.com - Daily MedNews - October 1, 2019 Category: General Medicine Source Type: news

Incidence of stroke and traumatic brain injury in New Zealand: contrasting the BIONIC and ARCOS-IV studies.
CONCLUSIONS: Differences in TBI and stroke incidence suggest targeting prevention very differently for the two groups. Incidence profiles suggest TBI is much more common; and a need to target males and those of Māori ethnicity for TBI prevention. PMID: 31563926 [PubMed - in process]
Source: New Zealand Medical Journal - October 1, 2019 Category: General Medicine Tags: N Z Med J Source Type: research

The risk of stroke and associated risk factors in a health examination population: A cross-sectional study
This study estimates the risk of stroke and identify risk factors for people who underwent health examinations at the Health Examination Center at West China Hospital, Sichuan University from July 2014 to February 2018. A total of 31,464 people were recruited in this study and divided into 3 groups (low risk, moderate risk, and high risk) according to risk of stroke. We explored possible factors associated with the risk of stroke by using multivariable stepwise logistic regression analysis. Among the participants, 17,959 were at low risk, 11,825 were at moderate risk, and 1680 were at high risk. Age, smoking, alcohol con...
Source: Medicine - October 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Investigating the Relationship of the Functional Gait Assessment to Spatiotemporal Parameters of Gait and Quality of Life in Individuals With Stroke
Conclusions: The FGA is a clinical measure of functional gait performance that reflected spatiotemporal gait parameters and ability of individuals with chronic stroke to live independently. The FGA could be used to target interventions to improve functional gait performance of individuals with chronic stroke.
Source: Journal of Geriatric Physical Therapy - October 1, 2019 Category: Physiotherapy Tags: Research Reports Source Type: research

Social Participation Determines Quality of Life Among Urban-Dwelling Older Adults With Stroke in a Developing Country
Conclusion: Social participation and cognition were strong determinants of QoL among urban-dwelling older adults with stroke. Social and recreational activities and cognitive rehabilitation should therefore be evaluated as potential strategies to improve the well-being of older adults affected by stroke.
Source: Journal of Geriatric Physical Therapy - October 1, 2019 Category: Physiotherapy Tags: Research Reports Source Type: research

Unsedated Outpatient Percutaneous Endoscopic Gastrostomy in Stroke Patients: Is It Feasible and Safe?
This study sought to determine the feasibility and safety of outpatient, unsedated PEG implementation in stroke patients. This retrospective cohort study involved stroke victims who underwent unsedated outpatient PEG insertion from 2014 to 2017 at our Surgical Endoscopy Unit. Patients were given pharyngeal anesthesia with lidocaine 10% spray, while the PEG tube was placed under local anesthesia. The incidence of intraprocedural and postprocedural complications and 30-day mortality rate were recorded. Data from 127 cases were analyzed. The procedures were performed with minor, transient complications, which resolved after r...
Source: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques - October 1, 2019 Category: Surgery Tags: Original Articles Source Type: research

Imaging of Acute Stroke
This article reviews the current state of imaging for acute ischemic stroke. Protocolized imaging acquisition using computed tomography in conjunction with coordinated stroke care allows for rapid diagnosis and prompt revascularization. Following the initial evidence to support endovascular therapy for large-vessel occlusion, published between 2014 and 2015, there are now guidelines supporting treatment up to 24  hours after time of onset of symptoms. Neuroimaging remains a central component in diagnosing acute stroke and potentially excluding patients from stroke treatment, as outlined in this article.
Source: Radiologic Clinics of North America - October 1, 2019 Category: Radiology Authors: Steven Hetts, Rajkamal Khangura Source Type: research

Causes of Acute Stroke
This article reviews the imaging patterns of acute strokes, and how the infarct pattern and imaging characteristics can suggest an underlying cause.
Source: Radiologic Clinics of North America - October 1, 2019 Category: Radiology Authors: Ashley Knight-Greenfield, Joel Jose Quitlong Nario, Ajay Gupta Source Type: research

Pediatric Stroke: A Single-Center Experience
The aim of this study was to evaluate the clinical characteristics, risk factors, treatment, and outcomes of pediatric stroke cases. A total of 118 patients diagnosed with arterial ischemic stroke (AIS), hemorrhagic stroke, and sinovenous thrombosis (SVT) between January 2000 and December 2011 were included. Neonatal cases were excluded. Demographic and clinical findings were retrospectively examined from medical records. We identified 118 patients with stroke. The age of the patients ranged from 1 to 215 months (17.92 y), with a mean age of 5.19±5.25 years. AIS accounted for the majority of cases (n=69, 58.5%), and the...
Source: Journal of Pediatric Hematology Oncology - October 1, 2019 Category: Hematology Tags: Original Articles Source Type: research

Visit-to-visit Systolic Blood Pressure Variability and Stroke Risk: A Systematic Review and Meta-analysis
SummaryVisit-to-visit variability in systolic blood pressure (SBP) may have an important additional role in increasing the risk of vascular complications, including stroke. We conducted a meta-analysis to assess the relationship between visit-to-visit SBP variability (SBPV) and stroke risk. PubMed, EMBASE, and the Cochrane library databases were searched for cohort studies with data on visit-to-visit SBPV and stroke risk. Studies that reported adjusted relative risks (RRs) with 95% CIs of stroke associated with SBPV were included. Fourteen cohort studies met the inclusion criteria and were included in our meta-analysis. Af...
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - October 1, 2019 Category: Research Source Type: research

Dietary saturated fat intake and risk of stroke: systematic review and dose-response meta-analysis of prospective cohort studies
Due to the conflicting research results, the association of saturated fatty acid (SFA) consumption and the risk of stroke remains controversial. We conducted a meta-analysis to evaluate potential dose-response relations between SFA intake and stroke.
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - October 1, 2019 Category: Nutrition Authors: Zhou-Qing Kang, Ying Yang, Bo Xiao Tags: Systematic Reviews and Meta-analyses Source Type: research

Finger paresis as isolated manifestation of acute ischaemic stroke.
PMID: 31575679 [PubMed - as supplied by publisher]
Source: Practical Neurology - October 1, 2019 Category: Neurology Authors: Castillo-Torres SA, Ramírez-Gutiérrez R, Chávez-Luévanos BE Tags: Pract Neurol Source Type: research

Recurrent stroke: the role of thrombophilia in a large international pediatric stroke population.
PMID: 31575673 [PubMed - in process]
Source: Haematologica - October 1, 2019 Category: Hematology Authors: deVeber G, Kirkham F, Shannon K, Brandão L, Sträter R, Kenet G, Clausnizer H, Moharir M, Kausch M, Askalan R, MacGregor D, Stoll M, Torge A, Dlamini N, Ganesan V, Prengler M, Singh J, Nowak-Göttl U Tags: Haematologica Source Type: research

Category specific recall in acute stroke: a case with letter speech.
In this report, we describe a similar case with a transient episode of utterances of randomly selected letters. Like in the three previous cases, this episode was preceded by a brief stage of mutism and ultimately evolved to Wernicke's aphasia over a period of days. This phenomenon is reviewed with reference to linguistic models and neuroanatomic and neurophysiological correlates. PMID: 31571518 [PubMed - as supplied by publisher]
Source: Neurocase - October 1, 2019 Category: Neurology Authors: De Letter M, Van Borsel J, Lanckmans E, Batens K, Hemelsoet D, Duyck W, Fias W, Santens P Tags: Neurocase Source Type: research

Impaired H-Reflex Adaptations Following Slope Walking in Individuals With Post-stroke Hemiparesis
ConclusionSimilar pattern of change in peak propulsive and braking forces with respect to different slopes was observed in both individuals post-stroke and non-impaired individuals, but the magnitude of GRFs were smaller in individuals post-stroke due to the slower walking speed. Our results suggested that impaired modulation of the H-reflex pathway potentially underlies the lack of neuroadaptations in individuals with chronic post-stroke hemiparesis.
Source: Frontiers in Physiology - October 1, 2019 Category: Physiology Source Type: research

Hyponatremia in Acute Stroke: To Treat or Not to Treat?
Hyponatremia is the most common electrolyte disorder both in hospitalized patients and individuals from the community with a reported incidence mounting up to 30% and 8%, respectively.1,2 Its association with increased risk of mortality has been well-established.3-5 Several meta-analyses have demonstrated that hyponatremia increases mortality in patients with common clinical conditions, such as acute myocardial infarction, heart failure, cirrhosis, and chronic kidney disease,3-5 while “correction” of serum sodium levels improves survival.
Source: Journal of Stroke and Cerebrovascular Diseases - October 1, 2019 Category: Neurology Authors: Fotios Barkas, George Liamis, Haralampos Milionis Tags: Letter to the Editor Source Type: research

P5. Abstract Title: Characterization of Unfractionated Heparin Infusions in a Comprehensive Stroke Centre
Stroke patients with arterial or venous intraluminal thrombus (ILT) are at high risk of stroke recurrence and embolic or hemorrhagic complications. Treatment with anticoagulation remains challenging in this group of patients due to onset of action, efficacy, and risk of hemorrhage. Traditionally, unfractionated heparin (UFH) has been used due to its short half-life in the context of risk of hemorrhagic transformation of the infarct zone. Heparin nomograms and associated bolus dosing are not standardized in clinical practice across centres and patients can exhibit long epochs of time under or over the therapeutic PTT range.
Source: Thrombosis Research - October 1, 2019 Category: Hematology Authors: H. Khosravani, P. Pham, C. Shen, C. Wong Source Type: research

EP.57Duchenne muscular dystrophy and stroke: systematic review of literature and two cases reports
This article's aims are to systematically review medical literature and report two cases of caucasian patients having DMD and stroke.
Source: Neuromuscular Disorders - October 1, 2019 Category: Neurology Authors: B. Bolonhezi, L. Matsumura, K. Turke, L. Silva, A. Langer, D. Feder, A. Carvalho Source Type: research

Update on stroke.
PMID: 31588975 [PubMed - in process]
Source: Der Nervenarzt - October 1, 2019 Category: Neurology Authors: Dichgans M Tags: Nervenarzt Source Type: research

Systolic Hypertension, Preeclampsia-Related Mortality, and Stroke In California.
PMID: 31568350 [PubMed - in process]
Source: Obstetrics and Gynecology - October 1, 2019 Category: OBGYN Authors: Messerli FH, Raio L, Baumann M, Rimoldi S, Rexhaj E Tags: Obstet Gynecol Source Type: research

Interventions for preventing falls in people after stroke.
CONCLUSIONS: At present there exists very little evidence about interventions other than exercises to reduce falling post stroke. Low to very low quality evidence exists that this population benefits from exercises to prevent falls, but not to reduce number of fallers.Fall research does not in general or consistently follow methodological gold standards, especially with regard to fall definition and time post stroke. More well-reported, adequately-powered research should further establish the value of exercises in reducing falling, in particular per phase, post stroke. PMID: 31573069 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - October 1, 2019 Category: General Medicine Authors: Denissen S, Staring W, Kunkel D, Pickering RM, Lennon S, Geurts AC, Weerdesteyn V, Verheyden GS Tags: Cochrane Database Syst Rev Source Type: research

Patent Foramen Ovale and Ischemic Stroke in Patients With Pulmonary Embolism.
PMID: 31569246 [PubMed - in process]
Source: Annals of Internal Medicine - October 1, 2019 Category: Internal Medicine Authors: Le Moigne E, Jobic Y, Timsit S, Hoffmann C, Couturaud F Tags: Ann Intern Med Source Type: research

Structural basis for power stroke vs. Brownian ratchet mechanisms of motor proteins Biophysics and Computational Biology
Two mechanisms have been proposed for the function of motor proteins: The power stroke and the Brownian ratchet. The former refers to generation of a large downhill free energy gradient over which the motor protein moves nearly irreversibly in making a step, whereas the latter refers to biasing or rectifying...
Source: Proceedings of the National Academy of Sciences - October 1, 2019 Category: Science Authors: Wonmuk Hwang, Martin Karplus Tags: Perspective Source Type: research

Transfer of reactive balance adaptation from stance-slip perturbation to stance-trip perturbation in chronic stroke survivors.
CONCLUSIONS: Chronic stroke survivors demonstrated improved direction-specific compensatory stepping response on a novel trip-perturbation following reactive adaptation to large-magnitude, stance-slip perturbation training.New and Noteworthy:The present study investigates the ability of chronic stroke survivors to generalize motor adaptation from stance-slip perturbation training to a novel, diametrically opposing trip-perturbation. We report that the people with chronic hemi-paretic stroke could employ the acquired adaptation in reactive postural stability in order to improve reactive stepping responses to a novel stance-...
Source: Restorative Neurology and Neuroscience - September 30, 2019 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Contributions of 12/15-Lipoxygenase to Bleeding in the Brain Following Ischemic Stroke.
Authors: Zheng Y, Liu Y, Karatas H, Yigitkanli K, Holman TR, van Leyen K Abstract Ischemic strokes are caused by one or more blood clots that typically obstruct one of the major arteries in the brain, but frequently also result in leakage of the blood-brain barrier and subsequent hemorrhage. While it has long been known that the enzyme 12/15-lipoxygenase (12/15-LOX) is up-regulated following ischemic strokes and contributes to neuronal cell death, recent research has shown an additional major role for 12/15-LOX in causing this hemorrhagic transformation. These findings have important implications for the use of 12/...
Source: Advances in Experimental Medicine and Biology - September 30, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research

Trends in Stroke Incidence Rates in Older US Adults
This cohort study evaluates whether stroke incidence declined among older adults from 1987 to 2011 vs 2011 to 2017 in the Atherosclerosis Risk in Communities study.
Source: JAMA Neurology - September 30, 2019 Category: Neurology Source Type: research

Monocyte/lymphocyte ratio is associated with carotid stenosis in ischemic stroke: A retrospective analysis
ConclusionMonocyte/lymphocyte ratio plays important roles in carotid stenosis in patients with ischemic stroke and is an independent risk factor of the severity of carotid stenosis. Therefore, MLR might be considered a potential index in the diagnosis of carotid stenosis in patients with ischemic stroke.
Source: Brain and Behavior - September 30, 2019 Category: Neurology Authors: Bo Zuo, Sha Zhu, Xue Meng, Danhua Zhao, Jun Zhang Tags: ORIGINAL RESEARCH Source Type: research

Association between Lys198Asn polymorphism of endothelin ‐1 gene and ischemic stroke: A meta‐analysis
ConclusionsThe present meta ‐analysis suggests that Lys198Asn polymorphism of EDN1 gene is associated with an increased risk for ischemic stroke.
Source: Brain and Behavior - September 30, 2019 Category: Neurology Authors: Gaurav Nepal, Rajeev Ojha, Hari Prasad Dulal, Binod Kumar Yadav Tags: ORIGINAL RESEARCH Source Type: research

Neutrophil –lymphocyte ratio predicts post‐thrombolysis early neurological deterioration in acute ischemic stroke patients
ConclusionsThis study showed that elevated level of NLR may predict post ‐thrombolysis END in ischemic stroke patients.
Source: Brain and Behavior - September 30, 2019 Category: Neurology Authors: Pengyu Gong, Yi Xie, Teng Jiang, Yukai Liu, Meng Wang, Huanhuan Sun, Shuting Zhang, Yingdong Zhang, Xiaohao Zhang, Junshan Zhou Tags: ORIGINAL RESEARCH Source Type: research

From clinical appearance to accurate management in acute ischemic stroke patients: With the guidance of innovative traditional Chinese medicine diagnosis
ConclusionsThe four ‐type simplified classification of Integrated TCM and Western medicine in acute ischemic stroke has specific laboratory data to support. Simplified classification with TCM treatment and intervention of different patients improves the survival and treatment, which is an innovative, easy‐to‐mas ter clinical diagnosis and treatment model.
Source: Brain and Behavior - September 30, 2019 Category: Neurology Authors: Juexian Song, Cuiyu Xu, Jing Zhang, Li Gao Tags: ORIGINAL RESEARCH Source Type: research

Stroke Risk as a Function of Atrial Fibrillation Duration and CHA2DS2-VASc Score.
Conclusions: There is an interaction between AF duration and CHA2DS2-VASc score which can further risk stratify AF patients for SSE and may be useful in guiding anticoagulation therapy. PMID: 31564126 [PubMed - as supplied by publisher]
Source: Circulation - September 30, 2019 Category: Cardiology Authors: Kaplan RM, Koehler J, Ziegler PD, Sarkar S, Zweibel S, Passman RS Tags: Circulation Source Type: research

Severe Periodontitis Is Associated with Early-Onset Poststroke Depression Status
In this study, we aimed to investigate whether there is an association between severe periodontitis and PSD status in acute ischemic stroke patients.
Source: Journal of Stroke and Cerebrovascular Diseases - September 30, 2019 Category: Neurology Authors: Weifeng Lin, Li Xiong, Zhi Yang, Xuhui Deng, Jinhua Zhu, Chunchun Chen, Shuxuan Huang, Ying Ma, Feiqi Zhu Source Type: research

Effectiveness of Wii Fit Balance board in comparison with other interventions for post-stroke balance rehabilitation. Systematic review and meta-analysis.
CONCLUSION: Wii Fit Balance, virtual reality platform, is an available therapeutic tool which has been shown at least as effective as conventional balance training in post-stroke patients. PMID: 31559625 [PubMed - in process]
Source: Revista de Neurologia - September 29, 2019 Category: Neurology Authors: Garcia-Munoz C, Casuso-Holgado MJ Tags: Rev Neurol Source Type: research

Development of a flexible rehabilitation concept for a neurological in-patient rehabilitation program after stroke.
CONCLUSION: The evidence-based and consensus-based concept is characterized by being individually and flexibly applicable to the individual patient. In this way, it meets the given demands and fulfils the requirements of a heterogeneous group of patients. It is intended to incorporate the treatment concept into the routine healthcare services offered by the AOK Baden-Württemberg. In addition, the treatment concept will be the basis for the development of performance-based remuneration. PMID: 31558374 [PubMed - as supplied by publisher]
Source: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen - September 29, 2019 Category: Health Management Tags: Z Evid Fortbild Qual Gesundhwes Source Type: research

IJERPH, Vol. 16, Pages 3665: Knowledge and Poor Understanding Factors of Stroke and Heart Attack Symptoms
Conclusions: Specialized interventions, including those based on public education, should focus on groups with less knowledge of CVD.
Source: International Journal of Environmental Research and Public Health - September 29, 2019 Category: Environmental Health Authors: Chang Hoon Han Hyeyun Kim Sujin Lee Jae Ho Chung Tags: Article Source Type: research

Poor enhancement pattern of left atrial appendage in cardiac computed tomography is associated with stroke in persistent atrial fibrillation patients.
Conclusions: The LAA enhancement pattern observed using cardiac CT is associated with the risk of stroke. Poor enhancement in the LAA suggests a potential high risk of stroke. PMID: 31559034 [PubMed]
Source: Journal of Thoracic Disease - September 28, 2019 Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research

Personality traits and the risk of coronary heart disease or stroke in women with diabetes – an epidemiological study based on the Women's Health Initiative
Conclusions: Hostility was associated with incidence of CHD among postmenopausal women with diabetes, especially among incident diabetes. These results provide a basis for targeted prevention programs for women with a high level of hostility and diabetes.
Source: Menopause - September 28, 2019 Category: OBGYN Tags: Original Articles Source Type: research

Stroke in supplementary motor area mimicking functional disorder: a case report
We report a 59-year-old man with previous history for myocardial infarction, referred to emergency room with an acute dense right-side hemiplegia, positive Hoover sign, asymmetrical Babinski responses and intermittent ability to move his arm in some specific reflex actions despite plegia. Since brain computed tomography scan was unremarkable we could not be sure whether his symptoms were organic or functional until a diffusion weighted imaging of magnetic resonance imaging elucidated the situation. To our knowledge, there is only one case report in the literature prior to ours, presenting a supplementary motor area stroke ...
Source: Journal of Neurology - September 28, 2019 Category: Neurology Source Type: research

Influence of neurorehabilitation on stroke-induced modifications of the quadriceps muscle in elderly subacute stroke patients with paresis.
Authors: Ciancarelli I, Mariangeli F, Tonin P, Ciofani E, Garo ML, Ciancarelli MGT Abstract The influence of intensive multifunctional neurorehabilitation on post-stroke changes at the level of the paretic leg quadriceps muscle was examined in elderly subacute stroke patients. We assessed paretic leg muscle mass thickness and muscle fatty infiltration thickness, as well as clinical outcome measures (National Institutes of Health Stroke Scale, modified Ranking Scale, and Barthel Index) both before and after neurorehabilitation. Improved outcome measures (p ≤ 0.01) and increased muscle mass thickness (p = 0.005) wi...
Source: Functional Neurology - September 28, 2019 Category: Neurology Tags: Funct Neurol Source Type: research

Risk factors and subtypes of ischemic stroke in young patients: an observational study from a teaching hospital in Saudi Arabia.
Authors: Shahid R Abstract Young adults are a key part of any society and the psychosocial and economic burden of any chronic or devastating disease in this particular group has significant consequences and impacts negatively on the development of the society as a whole. Although stroke in this age group is relatively rare, its consequences, in terms of lifelong dependence and disability, are substantial. Therefore, it is important to address this issue. In this retrospective epidemiological study, we analyzed the medical records of young patients (aged 18- 45 years) with a diagnosis of stroke during the study peri...
Source: Functional Neurology - September 28, 2019 Category: Neurology Tags: Funct Neurol Source Type: research

Cerebellar fastigial nucleus is involved in post-stroke depression through direct cerebellar-hypothalamic GABAergic and glutamatergic projections.
Authors: Li Y, Zhang X, Chen L, Yang B, Sui R Abstract The present study aimed to investigate whether the cerebellar fastigial nucleus (FN) is involved in post-stroke depression (PSD), and to observe the effect of direct cerebellar-hypothalamic γ-aminobutyric acid (GABA)ergic and glutamatergic projections on PSD, in order to understand the mechanisms underlying the cerebellar modulation of mood and emotion. Healthy Sprague-Dawley rats were randomly divided into five groups: Sham-operated, Stroke, PSD, FN lesion, and decussation of superior cerebellar peduncle (XSCP) lesion groups. Sham surgery was performed in ani...
Source: Experimental and Therapeutic Medicine - September 28, 2019 Category: General Medicine Tags: Exp Ther Med Source Type: research