Query: stroke

This page shows you your search results in order of date. This is page number 18.

Order by Relevance | Date

Total 81682 results found since Jan 2013.

Different Influences of Statin Treatment in Preventing At-Risk Stroke Subtypes: A Post Hoc Analysis of J-STARS.
CONCLUSIONS: Statins showed different influences on the risks of atherothromobotic and lacunar stroke according to postrandomized LDL cholesterol levels. PMID: 31534062 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - September 20, 2019 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

Effects on walking of simultaneous upper/lower limb abobotulinumtoxina injections in patients with stroke or brain injury with spastic hemiparesis.
CONCLUSION: Simultaneous lower and upper limb abobotulinumtoxinA treatment does not hamper improvement in walking speed compared with lower limb treatment alone. Thus, physicians may split the 1,500 U abobotulinumtoxinA dose as needed to best treat patients with spastic paresis. PMID: 31529136 [PubMed - as supplied by publisher]
Source: Journal of Rehabilitation Medicine - September 20, 2019 Category: Rehabilitation Tags: J Rehabil Med Source Type: research

Gait Velocity and Joint Power Generation After Stroke: Contribution of Strength and Balance
Conclusions Ankle plantar flexor and hip flexor strength had the largest contribution to gait velocity. Future research may wish to refocus strength assessment and treatment to target the ankle plantar flexors and hip flexors. To Claim CME Credits Complete the self-assessment activity and evaluation online at http://www.physiatry.org/JournalCME CME Objectives Upon completion of this article, the reader should be able to: (1) Differentiate the contribution that lower limb strength of each muscle group has on gait velocity after stroke; (2) Appraise the relationship between isometric strength and joint power generati...
Source: American Journal of Physical Medicine and Rehabilitation - September 20, 2019 Category: Rehabilitation Tags: CME Article . 2019 Series . Number 10 Source Type: research

Health Tip: Controllable Stroke Risk Factors
-- More than 750,000 people have a stroke each year in the United States, says Cleveland Clinic. But as many as half of all strokes are preventable, the clinic says. Risk factors that are under all or partial control include: High blood...
Source: Drugs.com - Daily MedNews - September 20, 2019 Category: General Medicine Source Type: news

AHA News: These Diets Helped Women With Diabetes Cut Heart Attack, Stroke Risk
Title: AHA News: These Diets Helped Women With Diabetes Cut Heart Attack, Stroke RiskCategory: Health NewsCreated: 9/19/2019 12:00:00 AMLast Editorial Review: 9/20/2019 12:00:00 AM
Source: MedicineNet Diabetes General - September 20, 2019 Category: Endocrinology Source Type: news

Health Tip: Controllable Stroke Risk Factors
Title: Health Tip: Controllable Stroke Risk FactorsCategory: Health NewsCreated: 9/20/2019 12:00:00 AMLast Editorial Review: 9/20/2019 12:00:00 AM
Source: MedicineNet Heart General - September 20, 2019 Category: Cardiology Source Type: news

Practice Variations in the Use of Novel Oral Anticoagulants for Nonvalvular Atrial Fibrillation-Related Stroke among Stroke Neurologists in Saudi Arabia.
In conclusion, the practice of stroke neurologists is consistent with and supports the available evidence from observational studies on the time of initiation of NOACs. Our findings provide a guide for clinicians who manage nvAF-related stroke until more robust evidence from randomized controlled trials is available. PMID: 31531241 [PubMed]
Source: Neurology Research International - September 20, 2019 Category: Neurology Tags: Neurol Res Int Source Type: research

Epidemiologic features and risk factors of sepsis in ischemic stroke patients admitted to intensive care: A prospective cohort study
ConclusionsThis study showed that ICU patients with severe ischemic stroke were more susceptible to sepsis during the hospital course.
Source: Journal of Clinical Neuroscience - September 20, 2019 Category: Neuroscience Source Type: research

Stroke Complicating Acute ST Elevation Myocardial Infarction —Current Concepts
Int J Angiol DOI: 10.1055/s-0039-1695049Myocardial infarction (MI) is one of the leading causes of mortality today both in developed and developing countries alike. Advancement in the pharmacotherapy and revascularization techniques has resulted in drastic improvement in survival. Most of the complications of MI can be managed adequately resulting in reduced mortality from MI in the recent years. However, mortality from stroke following acute MI remains high even today. Here, we discuss the incidence, risk factors, and management of stroke following acute ST elevation MI. [...] Thieme Medical Publishers 333 Seventh Avenue,...
Source: International Journal of Angiology - September 20, 2019 Category: Cardiology Authors: Bhandari, Monika Vishwakarma, Pravesh Sethi, Rishi Pradhan, Akshyaya Tags: Review Article Source Type: research

Association of trans-myocardial repolarisation parameters with size of the diffusion limitation area in acute ischaemic stroke.
CONCLUSIONS: When we compared the patients with ischaemic stroke who had no known cardiac disease to those in the control group we found an increase in transmyocardial repolarisation parameters. As diffusion limitation areas grew larger, QT, QTc, P, and Tp-e dispersions increased. Physicians should be aware of dysrhythmias and sudden cardiac death in acute stroke and should observe these patients, especially those with larger stroke lesions. PMID: 31538656 [PubMed - as supplied by publisher]
Source: Neurologia i Neurochirurgia Polska - September 20, 2019 Category: Neurology Authors: Uzunosmanoğlu H, Korucu O, Emektar E, Çorbacıoğlu ŞK, Hacıfazlıoğlu Ç, Çevik Y Tags: Neurol Neurochir Pol Source Type: research

Protocol for AREST: Apixaban for Early Prevention of Recurrent Embolic Stroke and Hemorrhagic Transformation —A Randomized Controlled Trial of Early Anticoagulation After Acute Ischemic Stroke in Atrial Fibrillation
Discussion: AREST will offer randomized controlled trial data about timeliness and safety of anticoagulation in AIS patients with AF.Clinical Trial Registration:www.ClinicalTrials.gov, identifier NCT02283294.
Source: Frontiers in Neurology - September 20, 2019 Category: Neurology Source Type: research

Atrial Fibrillation and Stroke. A Review on the Use of Vitamin K Antagonists and Novel Oral Anticoagulants.
Abstract Atrial fibrillation (AF) is the most common arrhythmia, ranging from 0.1% in patients <55 years to >9% in octogenarian patients. One important issue is represented by the 5-fold increased ischemic stroke risk in AF patients. Hence, the role of anticoagulation is central. Until a few years ago, vitamin K antagonists (VKAs) and low molecular weight heparin represented the only option to prevent thromboembolisms, though with risks. Novel oral anticoagulants (NOACs) have radically changed the management of AF patients, improving both life expectancy and life quality. This review aims to summarize the mo...
Source: Medicina (Kaunas) - September 20, 2019 Category: Universities & Medical Training Authors: Caturano A, Galiero R, Pafundi PC Tags: Medicina (Kaunas) Source Type: research

Subclinical Atrial Fibrillation and Risk of Stroke: Past, Present and Future.
Abstract Subclinical atrial fibrillation (SCAF) describes asymptomatic episodes of atrial fibrillation (AF) that are detected by cardiac implantable electronic devices (CIED). The increased utilization of CIEDs renders our understanding of SCAF important to clinical practice. Furthermore, 20% of AF present initially as a stroke event and prolonged cardiac monitoring of stroke patients is likely to uncover a significant prevalence of SCAF. New evidence has shown that implanting cardiac monitors into patients with no history of atrial fibrillation but with risk factors for stroke will yield an incidence of SCAF appr...
Source: Medicina (Kaunas) - September 20, 2019 Category: Universities & Medical Training Authors: AlTurki A, Marafi M, Russo V, Proietti R, Essebag V Tags: Medicina (Kaunas) Source Type: research

Social Support as a Predictor of Community Participation After Stroke
This study aimed to examine the independent contribution of perceived social support to participation 3 months post discharge from inpatient stroke rehabilitation. This study was a secondary analysis of the Stroke Recovery in Underserved Populations 2005–2006 data. Participants were adults ≥55 years old, living in the community 3 months post discharge from inpatient rehabilitation for ischemic stroke (n = 422). Hierarchical linear regressions were performed. The primary variables of interest were the PAR-PRO Measure of Home and Community Participation and the Duke–University of North Carolina Functional Social Suppor...
Source: Frontiers in Neurology - September 20, 2019 Category: Neurology Source Type: research

Balloon Guide Catheter in Endovascular Treatment for Acute Ischemic Stroke: Results from the MR CLEAN Registry
ConclusionsIn clinical practice, use of a BGC was associated with higher reperfusion grade and early improvement of neurologic deficits, but had no positive effect on long-term functional outcome.
Source: Journal of Vascular and Interventional Radiology - September 19, 2019 Category: Radiology Source Type: research

Clinical efficacy of tirofiban combined with a Solitaire stent in treating acute ischemic stroke.
This study explores the safety and effect of acute cerebral infarction treatment by microcatheter injection of tirofiban combined with a Solitaire AB stent and/or stent implantation. Emergency cerebral angiograms showing the responsible vascular occlusion of 120 acute cerebral infarction patients who underwent emergency endovascular thrombectomy were included in the study. These patients were randomly divided into two groups using the random number table method: treatment group (n=60) that received thrombectomy (with cerebral artery stents) combined with intracerebral injection of tirofiban and control group (n=60) that on...
Source: Braz J Med Biol Res - September 19, 2019 Category: Research Authors: Zhang Y, Zhang QQ, Fu C, Wang L, Zhang GQ, Cao PW, Chen GF, Fu XM Tags: Braz J Med Biol Res Source Type: research

Relationship of chronic rhinosinusitis with asthma, myocardial infarction, stroke, anxiety, and depression
ConclusionCRS is associated with an increased incidence of asthma, AMI, stroke, anxiety disorder, and depression. Therefore, we suggest that clinicians should monitor CRS patients carefully, and optimize management as a means to potentially decrease these other associated comorbid conditions.
Source: The Journal of Allergy and Clinical Immunology: In Practice - September 19, 2019 Category: Allergy & Immunology Source Type: research

Quantitative and Qualitative EEG as a Prediction Tool for Outcome and Complications in Acute Stroke Patients.
Abstract Currently, the relevance of EEG measurements in acute stroke patients is considered low in clinical practice. However, recent studies on the predictive value of EEG measurements after stroke for various outcomes may increase the role of EEG in patients with stroke. We aimed to review the current literature on the utility of EEG measurements after stroke as a tool to predict outcome and complications, focusing on studies in which the EEG measurement was performed in the acute phase after the event and in which long-term outcome measures were reported. In our literature review, we identified 4 different out...
Source: Clinical EEG and Neuroscience - September 19, 2019 Category: Neuroscience Authors: Doerrfuss JI, Kilic T, Ahmadi M, Holtkamp M, Weber JE Tags: Clin EEG Neurosci Source Type: research

IJERPH, Vol. 16, Pages 3491: The Relationship between Scabies and Stroke: A Population-Based Nationwide Study
Conclusions: The results of the study indicated an elevated risk of stroke among scabies patients, an association that might be contributed to by immunopathological factors. This information could serve as a reminder to clinicians to remain alert to any indications of neurological impairment in patients previously infected with scabies.
Source: International Journal of Environmental Research and Public Health - September 19, 2019 Category: Environmental Health Authors: Meng-Huan Wu Chien-Yu Li Huichin Pan Yu-Chieh Lin Tags: Article Source Type: research

IJERPH, Vol. 16, Pages 3488: Perspectives on Disability and Non-Communicable Diseases in Low- and Middle-Income Countries, with a Focus on Stroke and Dementia
per Non-communicable diseases (NCD) and disability are both common, and increasing in magnitude, as a result of population ageing and a shift in disease burden towards chronic conditions. Moreover, disability and NCDs are strongly linked in a two-way association. People living with NCDs may develop impairments, which can cause activity limitations and participation restriction in the absence of supportive personal and environmental factors. In other words, NCDs may lead to disabilities. At the same time, people with disabilities are more vulnerable to NCDs, because of their underlying health condition, and vulnerabilit...
Source: International Journal of Environmental Research and Public Health - September 19, 2019 Category: Environmental Health Authors: Josephine E. Prynn Hannah Kuper Tags: Review Source Type: research

Discovery of a New Biomarker Pattern for Differential Diagnosis of Acute Ischemic Stroke Using Targeted Metabolomics
Stroke is one of the leading causes of disability all over the world. However, biomarkers for fast differential diagnosis of acute ischemic stroke (AIS) from vertigo or headache, remains lacking. Using a direct-infusion mass spectrometry method, it is possible to establish an efficient method for AIS differential diagnosis that requires only a few minutes. Thirty-eight clearly diagnosed AIS patients and 46 patients with a main complaint of vertigo were enrolled in this study. There was a total of 58 metabolites that were measured by our targeted metabolomics method, and the data were analyzed by pattern recognition algorit...
Source: Frontiers in Neurology - September 19, 2019 Category: Neurology Source Type: research

Brain stimulation for treating stroke-related motor deficits.
Abstract Functional recovery of stroke-related deficits is mainly achieved through neural reorganization. Neurorehabilitative approaches, therefore, aim at supporting positive processes while suppressing maladaptive neuronal processes. This review summarizes the main findings of studies using non-invasive and invasive brain stimulation with respect to the benefits of the treatment for motor deficits after stroke. In addition, the article discusses possible approaches to enhance the effectiveness of neuromodulatory approaches and thus improve the outcome of patients. PMID: 31538210 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - September 19, 2019 Category: Neurology Authors: Tscherpel C, Grefkes C Tags: Nervenarzt Source Type: research

Vegetarians have higher risk for stroke, lower heart disease risk
(Reuters Health) - People who follow vegetarian or vegan diets may have lower odds for heart disease but higher chances of having a stroke, compared to meat eaters, a large UK study suggests.
Source: Reuters: Health - September 18, 2019 Category: Consumer Health News Tags: healthNews Source Type: news

Theoretical modeling of spatial accessibility in the management of stroke in the Rhône department (France) and comparison with measured data
ConclusionTheoretical models were highly correlated and the correlation with the measured data was mostly correct. The few minutes difference between theoretical models and measured data could be explained by traffic hazards and organizational vagaries that always tend to disrupt modeling results. Using measured data was found to be very useful to perform theorical model and to develop a robust model of stroke transportation.
Source: Journal of Transport and Health - September 18, 2019 Category: Occupational Health Source Type: research

Training-Induced Neural Plasticity and Strength Are Amplified After Stroke
Following stroke, sensorimotor brain networks and descending regulation are compromised but spinal interlimb neural connections remain morphologically intact. After cross-education strength and locomotion training, amplified neural plasticity and functional responses are observed in chronic stroke compared with neurologically intact participants. We hypothesize that poststroke neuroplasticity is amplified because of the involvement of interlimb neural connections that persist from our quadrupedal ancestry.
Source: Exercise and Sport Sciences Reviews - September 18, 2019 Category: Sports Medicine Tags: Articles Source Type: research

Safety and effectiveness of CATCH+ as a first-line device for revascularization in the treatment of acute ischemic stroke
Conclusions: The CATCH+ device is a safe and effective mechanical thrombectomy device for the first-line treatment of acute ischemic stroke.
Source: Journal of Neuroradiology - September 18, 2019 Category: Radiology Source Type: research

Brain computerized tomography reading in suspected acute ischemic stroke patients: what are essentials for medical students?
Few systematic methods prioritize the image education in medical students (MS). We hope to develop a checklist of brain computerized tomography (CT) reading in patients with suspected acute ischemic stroke (AI...
Source: BMC Medical Education - September 18, 2019 Category: Universities & Medical Training Authors: Chi-Hung Liu, Cheng-Ting Hsiao, Ting-Yu Chang, Yeu-Jhy Chang, Sheng-Han Kuo, Chun-Wei Chang, Chi-Jen Chen, Chien-Fu Chen, Po-Liang Cheng, Shy-Chyi Chin, Te-Fa Chiu, Jung-Lung Hsu, Peng-Wei Hsu, Tsong-Hai Lee, Chih-Hsiang Liao, Chun-Jen Lin & hellip; Tags: Research article Source Type: research

Costs of hospitalization for stroke from two urban health insurance claims data in Guangzhou City, southern China
This study aimed to examine the hospitalization costs by five ...
Source: BMC Health Services Research - September 18, 2019 Category: General Medicine Authors: Hui Zhang, Yujie Yin, Chao Zhang and Donglan Zhang Tags: Research article Source Type: research

Lacunar stroke syndromes as predictors of lacunar and non-lacunar infarcts on neuroimaging: a hospital-based study
AbstractLacunar syndromes are usually caused by small ischemic lesions called lacunar infarcts. However, non-lacunar infarcts account for about 20% of lacunar syndromes. The aim of this study was to identify clinical predictors of lacunar syndromes led by non-lacunar infarcts. The following single centre, observational study was conducted on an analysis of the “Perugia hospital-based Stroke Registry” database enrolling consecutive patients admitted with ischemic stroke during the period 2010–2017. We evaluated patient risk factors and clinical features linked to stroke syndrome (lacunar/non-lacunar) and to cerebral i...
Source: Internal and Emergency Medicine - September 18, 2019 Category: Emergency Medicine Source Type: research

IJERPH, Vol. 16, Pages 3472: Exploration of Medical Trajectories of Stroke Patients Based on Group-Based Trajectory Modeling
In this study, we used group-based trajectory modeling (GBTM) to study the characteristics of various groups of patients hospitalized with ACVD. In this research, the patient data were derived from the 1 million sampled cases in the National Health Insurance Research Database (NHIRD) in Taiwan. Cases who had been admitted to hospitals fewer than four times or more than eight times were excluded. Characteristics of the ACVD patients were collected, including age, mortality rate, medical expenditure, and length of hospital stay for each admission. We then performed GBTM to examine hospitalization patterns in patients who had...
Source: International Journal of Environmental Research and Public Health - September 18, 2019 Category: Environmental Health Authors: Ting-Ying Chien Mei-Lien Lee Wan-Ling Wu Hsien-Wei Ting Tags: Article Source Type: research

Infectious Etiologies of Stroke
Semin Neurol 2019; 39: 482-494 DOI: 10.1055/s-0039-1687915Central nervous system (CNS) infections are a frequently underappreciated potential etiology of cerebrovascular disease. Highlighted in this review are a selection of infectious agents that lead to cerebrovascular complications through various mechanisms including multifocal vasculopathy, focal infiltrative vasculitis and vasospasm, and direct vessel wall invasion and thrombus formation. Diagnosis of stroke due to underlying CNS infection requires a high index of clinical suspicion and careful consideration of neuroimaging, serum, and cerebrospinal fluid studies in ...
Source: Seminars in Neurology - September 18, 2019 Category: Neurology Authors: Shulman, Julie G. Cervantes-Arslanian, Anna M. Tags: Review Article Source Type: research

Analysis of comorbidities in hospitalized patients for ischemic stroke and their effects on lethality.
CONCLUSION: This study demonstrates that medico-administrative databases and factorial statistical methods are perfectly adapted to confirm the ischemic stroke risk factors. This type of study will allow to target with more precision the secondary and tertiary prevention actions of stroke. PMID: 31542203 [PubMed - as supplied by publisher]
Source: Annales de Cardiologie et d'Angeiologie - September 18, 2019 Category: Cardiology Authors: Savsin M, Dubourg D, Coppieters Y, Collart P Tags: Ann Cardiol Angeiol (Paris) Source Type: research

Balloon Guide Catheter in Endovascular Treatment for Acute Ischemic Stroke: Results from the MR CLEAN Registry
To compare outcomes after endovascular treatment (EVT) for acute ischemic stroke with and without the use of a balloon guide catheter (BGC) in clinical practice.
Source: Journal of Vascular and Interventional Radiology : JVIR - September 18, 2019 Category: Radiology Authors: Robert-Jan B. Goldhoorn, Nele Duijsters, Charles B.L.M. Majoie, Yvo B.W.E.M. Roos, Diederik W.J. Dippel, Adriaan C.G.M. van Es, Jan Albert Vos, Jelis Boiten, Robert J. van Oostenbrugge, Wim H. van Zwam, MR CLEAN Registry Investigators Tags: Clinical Study Source Type: research

Stress Hyperglycemia and Outcome of Non-diabetic Patients After Acute Ischemic Stroke
Conclusion: Stress hyperglycemia, measured by glucose-to-HbA1c ratio, was related to an elevated risk of stroke recurrence and all-cause death in patients with acute ischemic stroke but without diabetes.
Source: Frontiers in Neurology - September 18, 2019 Category: Neurology Source Type: research

Reperfusion therapy for minor stroke: A systematic review and meta ‐analysis
ConclusionsAlthough thrombolysis might increase the risk of ICH based on existing studies, patients with acute minor ischemic stroke could still benefit from thrombolysis at 3  months from the onset.
Source: Brain and Behavior - September 18, 2019 Category: Neurology Authors: Lihuan Lan, Xiaoming Rong, Xiangpen Li, Xiaoni Zhang, Jingrui Pan, Hongxuan Wang, Qingyu Shen, Ying Peng Tags: ORIGINAL RESEARCH Source Type: research

Device closure for patent foramen ovale in patients with cryptogenic stroke: a paradigm in evidence.
Authors: Ha FJ, Adams H, Palmer S PMID: 31523821 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - September 17, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Stem cell injections boost 25 stroke patients' recovery 'by helping nerve cells regrow
Scientists at the University of Texas said they saw an improvement of one point on a six-point scale after six months of testing the therapy on stroke patients within 72 hours of symptoms beginning.
Source: the Mail online | Health - September 17, 2019 Category: Consumer Health News Source Type: news

People living in noisy traffic areas may be 30 per cent more likely to have a deadly stroke
Researchers in Barcelona analysed records of more than 2,700 stroke victims in Spain and also found that having a 984-foot (300m) 'buffer' of green space around the home reduced stroke risk.
Source: the Mail online | Health - September 17, 2019 Category: Consumer Health News Source Type: news

Aggregation of human mesenchymal stem cells enhances survival and efficacy in stroke treatment
In this study, we report the effects of short-term preconditioning of hMSCs via three-dimensional (3D) aggregation on stroke lesion recovery after intra-arterial (IA) transplantation of 3D aggregate-derived hMSCs (Agg-D hMSCs) in a transient middle cerebral artery occlusion (MCAO) stroke model. Compared with two-dimensional (2D) monolayer culture, Agg-D hMSCs exhibited increased resistance to ischemic stress, secretory function and therapeutic outcome. Short-term preconditioning via 3D aggregation reconfigured hMSC energy metabolism and altered redox cycle, which activated the PI3K/AKT pathway and enhanced resistance to in...
Source: Cytotherapy - September 17, 2019 Category: Cytology Source Type: research

Nephrolithiasis predicts ischemic stroke: A longitudinal follow-up study using a national sample cohort.
This study sought to evaluate associations between nephrolithiasis and hemorrhagic and ischemic stroke using a national sample cohort from Korea. Data from 2002 to 2013 were collected for individuals ≥ 20 years of age in the Korean National Health Insurance Service (NHIS)-National Sample Cohort. We extracted nephrolithiasis patients (n = 22,636) and 1:4 matched controls (n = 90,544) and analyzed the occurrence of stroke. Matching was performed based on age, sex, income, region of residence, hypertension, diabetes mellitus, and dyslipidemia history. Crude and adjusted hazard ratios (HRs) were calculated using Cox proporti...
Source: International Journal of Medical Sciences - September 17, 2019 Category: Biomedical Science Tags: Int J Med Sci Source Type: research

Re-learning to be different: Increased neural differentiation supports post-stroke language recovery
Publication date: 15 November 2019Source: NeuroImage, Volume 202Author(s): Jeremy J. Purcell, Robert W. Wiley, Brenda RappAbstractIdentifying the neural changes that support recovery of cognitive functions after a brain lesion is important to advance our understanding of human neuroplasticity, which, in turn, forms the basis for the development of effective treatments. To date, the preponderance of neuroimaging studies has focused on localizing changes in average brain activity associated with functional recovery. Here, we took a novel approach by evaluating whether cognitive recovery in chronic stroke is related to increa...
Source: NeuroImage - September 17, 2019 Category: Neuroscience Source Type: research

Low Stroke Volume during Exercise with Hot Skin Is Due to Elevated Heart Rate
Conclusions The increase in HR rather than an increase in CBF or forearm venous volume was responsible for the decrease in SV during moderate-intensity exercise when Tsk was held at 38°C.
Source: Medicine and Science in Sports and Exercise - September 17, 2019 Category: Sports Medicine Tags: BASIC SCIENCES Source Type: research

Intravenous Bone Marrow Mononuclear Cells for Acute Ischemic Stroke: Safety, Feasibility, and Effect Size from a Phase I Clinical Trial
Diffusion tensor tractography using serial multimodel magnetic resonance imaging contrast in a representation patient who received autologous bone marrow ‐derived mononuclear cells after acute ischemic stroke. AbstractCellular therapy is a promising investigational modality to enhance poststroke recovery. We conducted a single ‐arm, phase I clinical trial to determine the safety and feasibility of intravenous (IV) administration of autologous bone marrow mononuclear cells (MNCs) after acute ischemic stroke (AIS). Patients with moderate severity of AIS underwent bone marrow harvest followed by IV reinfusion of MNCs with...
Source: Stem Cells - September 17, 2019 Category: Stem Cells Authors: Farhaan S. Vahidy, Muhammad E. Haque, Mohammad H. Rahbar, Hongjian Zhu, Paul Rowan, Imoigele P. Aisiku, Dean A. Lee, Harinder S. Juneja, Susan Alderman, Andrew D. Barreto, Jose I. Suarez, Arvind Bambhroliya, Khader M. Hasan, Mallikarjuna Rao Tags: Translational and Clinical Research Source Type: research

Comparison of sensitivity and plantar cutaneous temperature of patients with stroke and Diabetes Mellitus: A pilot case-control study.
CONCLUSIONS: There is no evidence that the cases and controls have different plantar sensibility nor different plantar temperature on their plegic and contralateral sides. However, significant temperature discrepancies between both plegic and contralateral sides were observed in the control group. PMID: 31594275 [PubMed - as supplied by publisher]
Source: Technology and Health Care - September 17, 2019 Category: Medical Devices Authors: Alfieri FM, da Silva Dias C, Dos Santos ACA, Battistella LR Tags: Technol Health Care Source Type: research

After stroke due to ICH while on antithrombotics, starting vs avoiding antiplatelets did not differ for symptomatic ICH.
PMID: 31525766 [PubMed - in process]
Source: Annals of Internal Medicine - September 17, 2019 Category: Internal Medicine Authors: Graham J Tags: Ann Intern Med Source Type: research

Knowledge and perceptions about perioperative stroke: a cross-sectional survey of patients scheduled for non-neurologic and non-cardiac surgery.
CONCLUSIONS: Patients at higher risk of stroke frequently underestimate their risk of perioperative stroke. The majority of patients had not discussed perioperative stroke prior to anesthetic consultation. PMID: 31531829 [PubMed - as supplied by publisher]
Source: Canadian Journal of Anaesthesia - September 17, 2019 Category: Anesthesiology Authors: Roughead T, Chui J, Gelb AW, Meng L, Sewell D, Flexman AM Tags: Can J Anaesth Source Type: research

Alcohol-Related Hospital Encounters Trigger Thrombotic and Hemorrhagic Vascular Events
We investigated the associations between alcohol-related emergency department visits and hospitalizations and vascular events including acute ischemic stroke, intracerebral hemorrhage (ICH), and subarachnoid hemorrhage.
Source: Journal of Stroke and Cerebrovascular Diseases - September 17, 2019 Category: Neurology Authors: Caroline Gentile, Laura Stein, Mandip S. Dhamoon Source Type: research

Association between promoter DNA methylation and gene expression in the pathogenesis of ischemic stroke.
Abstract To assess DNA methylation sites as well as gene expression related to ischemic stroke (IS) and comprehensively reveal their correlation and possible pathological mechanisms, we implemented (1) genome-wide DNA methylation profiling from the GEO repository related to IS with and without symptoms; (2) identification of differentially methylation positions (DMPs) and genes (DMGs), functional enrichment analysis along with DMG regulatory network construction; (3) validation tests of 2 differential methylation positions of interest as well as analogous gene expression in other datasets and in IS patients and co...
Source: Aging - September 17, 2019 Category: Biomedical Science Authors: Deng GX, Xu N, Huang Q, Tan JY, Zhang Z, Li XF, Wei JR Tags: Aging (Albany NY) Source Type: research

The association between children ’s common Chinese stroke errors and spelling ability
AbstractThe present study adopted an error analysis approach to examine the stroke errors committed by 43 Hong Kong Chinese children of Grades 1 and 3 from a Chinese Character Copying Task. It aimed to determine the common stroke error patterns, developmental changes and the cognitive problems implied. The different types of stroke errors and total number of correct stroke sequence were further linked to Chinese word spelling ability and associated cognitive-linguistic skills. Results revealed that wrong stroke sequence and wrong character configuration were the common stroke errors in both grades and Grade 3 students made...
Source: Reading and Writing - September 17, 2019 Category: Child Development Source Type: research