Query: stroke

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Astrocytes: Role and Functions in Brain Pathologies
Astrocytes are a population of cells with distinctive morphological and functional characteristics that differ within specific areas of the brain. Postnatally, astrocyte progenitors migrate to reach their brain area and related properties. They have a regulatory role of brain functions that are implicated in neurogenesis and synaptogenesis, controlling blood–brain barrier permeability and maintaining extracellular homeostasis. Mature astrocytes also express some genes enriched in cell progenitors, suggesting they can retain proliferative potential. Considering heterogeneity of cell population, it is not surprising that t...
Source: Frontiers in Pharmacology - September 27, 2019 Category: Drugs & Pharmacology Source Type: research

Chronological in vivo imaging reveals endothelial inflammation prior to neutrophils accumulation and lipid deposition in HCD-fed zebrafish
This study explored the early events of atherogenesis in a hypercholesterolemic zebrafish model in vivo.
Source: Atherosclerosis - September 27, 2019 Category: Cardiology Authors: Hui Luo, Qi-qi Li, Ni Wu, Yu-ge Shen, Wei-ting Liao, Yun Yang, E. Dong, Gui-min Zhang, Bing-rui Liu, Xiao-zhu Yue, Xiao-qiang Tang, Han-shuo Yang Source Type: research

Nimodipine Reappraised: An Old Drug With a Future.
Abstract Nimodipine is a dihydropyridine calcium channel antagonist that blocks the flux of extracellular calcium through L-type, voltage-gated calcium channels. While nimodipine is FDA-approved for the prevention and treatment of neurological deficits in patients with aneurysmal subarachnoid hemorrhage (aSAH), it affects myriad cell types throughout the body, and thus, likely has more complex mechanisms of action than simple inhibition of cerebral vasoconstriction. Newer understanding of the pathophysiology of delayed ischemic injury after a variety of acute neurologic injuries including aSAH, traumatic brain inj...
Source: Current Neuropharmacology - September 27, 2019 Category: Drugs & Pharmacology Authors: Carlson AP, Hänggi D, Macdonald RL, Shuttleworth CW Tags: Curr Neuropharmacol Source Type: research

Atrial Fibrillation: Current Evidence and Management Strategies During the Perioperative Period.
Abstract Atrial fibrillation (AF) is the most common arrhythmia in the perioperative period. Previously considered a benign and self-limited entity, recent data suggest that perioperative AF is associated with considerable morbidity and mortality and may predict long-term AF and stroke risk in some patients. Despite known risk factors, AF remains largely unpredictable, especially after noncardiac surgery. As a consequence, strategies to minimize perioperative risk are mostly supportive and include avoiding potential arrhythmogenic triggers and proactively treating patient- and surgery-related factors that might pr...
Source: Anesthesia and Analgesia - September 27, 2019 Category: Anesthesiology Authors: Karamchandani K, Khanna AK, Bose S, Fernando RJ, Walkey AJ Tags: Anesth Analg Source Type: research

Statins: Complex outcomes but increasingly helpful treatment options for patients.
Abstract Statins are long known class of medicines and the most frequently prescribed drugs in cardiovascular pharmacotherapy, widely ordered not only in patients suffering from dyslipidemia, but also in patients with coronary artery disease, acute coronary syndromes, diabetes mellitus, stroke, hypertension, and chronic kidney disease, with or without coexisting dyslipidemia. However, several clinical trials have shown, that the advantages of statins goes beyond their reduction of the cholesterol level. Some crucial isoprenoid mediators which are highly essential for the activation of different intracellular/signa...
Source: European Journal of Pharmacology - September 27, 2019 Category: Drugs & Pharmacology Authors: Mohammadkhani N, Gharbi S, Fatima H, Farzaneh A, Mahjoob G, Hoseinsalari A, Korsching E Tags: Eur J Pharmacol Source Type: research

Prevalence and prognosis significance of cardiovascular disease in cancer patients: a population-based study.
CONCLUSIONS: Cancer patients are vulnerable to comorbidity related to heart and cerebral disease. The influence of comorbidities on prognosis is noticeable and specific both for the type of cancer and comorbidities. PMID: 31562288 [PubMed - as supplied by publisher]
Source: Aging - September 27, 2019 Category: Biomedical Science Authors: Liu D, Ma Z, Yang J, Zhao M, Ao H, Zheng X, Wen Q, Yang Y, You J, Qiao S, Yuan J Tags: Aging (Albany NY) Source Type: research

Viruses, Vol. 11, Pages 900: Hemodynamic and Pulmonary Permeability Characterization of Hantavirus Cardiopulmonary Syndrome by Transpulmonary Thermodilution
In conclusion, TPTD data suggest that in HCPS patients, increased permeability leads to PE, hypovolemia, and circulatory impairment.
Source: Viruses - September 27, 2019 Category: Virology Authors: Ren é López Rodrigo P érez-Araos Álvaro Salazar Ana L. Ulloa Cecilia Vial Pablo A. Vial Jer ónimo Graf Tags: Article Source Type: research

IJERPH, Vol. 16, Pages 3623: Effects of Chronic Comorbidities on the Health-Related Quality of Life among Older Patients after Falls in Vietnamese Hospitals
This study examines the prevalence of comorbidities and associations between comorbidities and HRQOL in older patients after falls in Vietnamese hospitals. A cross-sectional design was employed among 405 older patients admitted to seven hospitals due to fall injuries in Thai Binh province, Vietnam. The EuroQol-5 Dimensions-5 Levels (EQ-5D-5L) was used to measure HRQOL. Socio-demographic characteristics were collected using a structured questionnaire, while comorbidities and other clinical characteristics were examined by physicians and extracted from medical records. Multivariate Tobit regression was used to determine the ...
Source: International Journal of Environmental Research and Public Health - September 27, 2019 Category: Environmental Health Authors: Hai Minh Vu Long Hoang Nguyen Tung Hoang Tran Kiet Tuan Huy Pham Hai Thanh Phan Hieu Ngoc Nguyen Bach Xuan Tran Carl A. Latkin Cyrus S.H. Ho Roger C.M. Ho Tags: Article Source Type: research

Viruses, Vol. 11, Pages 900: Hemodynamic and Pulmonary Permeability Characterization of Hantavirus Cardiopulmonary Syndrome by Transpulmonary Thermodilution
In conclusion, TPTD data suggest that in HCPS patients, increased permeability leads to PE, hypovolemia, and circulatory impairment.
Source: Viruses - September 27, 2019 Category: Virology Authors: Ren é López Rodrigo P érez-Araos Álvaro Salazar Ana L. Ulloa Cecilia Vial Pablo A. Vial Jer ónimo Graf Tags: Article Source Type: research

Abiomed Hits TCT 2019 Running with Compelling Data and New Approval
Abiomed certainly brought its A-game to the 31st annual Transcatheter Cardiovascular Therapeutics (TCT) conference- being held now and throughout the weekend. The Danvers, MA-based company came armed with the news of a newly-approved device and data from its PROTECT III trial, an ongoing prospective, single-arm FDA post-market study for the Impella 2.5 and Impella CP in high-risk PCI. Abiomed, which was named one of the top 25 M&A targets in medtech, said an interim analysis of 898 patients from the PROTECT III trial demonstrated a reduction in the primary endpoint of death, stroke, myocardial infarction, and repeat pr...
Source: MDDI - September 26, 2019 Category: Medical Devices Authors: Omar Ford Tags: Cardiovascular Source Type: news

Platelet function, coagulation and fibrinolysis in patients with previous coronary and cerebrovascular ischemic events
CONCLUSION: Platelet aggregability, coagulation and endogenous fibrinolysis showed similar results among CAD patients with and without previous IS/TIA. Therefore, it remains necessary to identify other targets to explain the higher bleeding risk presented by these patients.
Source: Clinics - September 26, 2019 Category: General Medicine Source Type: research

Impact of Life's Simple 7 on the incidence of major cardiovascular events in high-risk Spanish adults in the PREDIMED study cohort
ConclusionsIn an elderly Spanish population at high cardiovascular risk, better adherence to Life's Simple 7 metrics was progressively associated with a substantially lower rate of major cardiovascular events.ResumenIntroducción y objetivosLa estrategia Life's Simple 7 de la American Heart Association propuso 7 métricas de salud cardiovascular ideal: índice de masa corporal (IMC) < 25, no fumar, dieta saludable, actividad física moderada ≥ 150 min a la semana, colesterol total < 200 mg/dl, presión arterial sistólica < 120 mmHg y diastólica < 80 mmHg y gl...
Source: Revista Espanola de Cardiologia - September 26, 2019 Category: Cardiology Source Type: research

Impact of Cerebral Perfusion on Outcomes of Aortic Surgery: STS Adult Cardiac Database Analysis
ConclusionsFor patients without dissection and requiring>30 minutes circulatory arrest, optimal cerebral protection strategies are deep hypothermia with either antegrade or retrograde cerebral perfusion; or moderate hypothermia with antegrade cerebral perfusion.
Source: The Annals of Thoracic Surgery - September 26, 2019 Category: Cardiovascular & Thoracic Surgery Source Type: research

Preface
Growing up in rural South India, I witnessed the lifelong effects of polio in my great-uncle and the effects of disability in my grandfather after he suffered a stroke. There were minimal access to health care of any type and no access to medical rehabilitation.
Source: Physical Medicine and Rehabilitation Clinics of North America - September 26, 2019 Category: Rehabilitation Authors: Joseph P. Jacob Source Type: research

What Does Head Impulse Testing Really Test?
To the Editor Walther et al ignore a fundamental rule of neurology: the pattern of the clinical or physiological deficit indicates the site and not the pathology of the lesion. This is the principle of neurological localization —there are textbooks written about it. The head impulse test, just like the caloric test, or the vestibular evoked myogenic potential, or an extensor plantar response can localize a lesion but reveal nothing about its pathology. For that, one needs to consider the history and results of ancillary investigations, say magnetic resonance imaging or spinal fluid test results. Impulsive testing can loc...
Source: JAMA Otolaryngology - Head and Neck Surgery - September 26, 2019 Category: ENT & OMF Source Type: research

Association of predicted lean body mass and fat mass with cardiovascular events in patients with type 2 diabetes mellitus.
Authors: Xing Z, Tang L, Chen J, Pei J, Chen P, Fang Z, Zhou S, Hu X Abstract BACKGROUND: Previous studies have found that predicted fat mass and lean body mass may act differently on adverse events. However, the cardiovascular prognostic value of lean body mass and fat mass in patients with type 2 diabetes mellitus (T2DM) has not yet been investigated. We sought to investigate the relation between predicted lean body mass or fat mass and the risk of cardiovascular disease in patients with T2DM. METHODS: We conducted a post hoc analysis of data from the Action to Control Cardiovascular Risk in Diabetes (ACCORD)...
Source: Canadian Medical Association Journal - September 26, 2019 Category: General Medicine Tags: CMAJ Source Type: research

Blood pressure and the brain: the neurology of hypertension.
Abstract Hypertension affects more than one in four adults. The brain is an early target of hypertension-induced organ damage, and may manifest as stroke, subclinical cerebrovascular abnormalities and dementia. Hypertension-related small vessel disease can cause vascular dementia and can potentiate Alzheimer's pathology, lowering the threshold at which signs and symptoms manifest. Many hypertensive emergencies may also have a neurological presentation, such as hypertensive encephalopathy, haemorrhagic stroke or pre-eclampsia. Here we highlight the importance of blood pressure in maintaining brain health and the br...
Source: Practical Neurology - September 26, 2019 Category: Neurology Authors: Kelly DM, Rothwell PM Tags: Pract Neurol Source Type: research

Cerebral Air Embolism after Esophagogastroduodenoscopy: Insight on Pathophysiology, Epidemiology, Prevention and Treatment
Air embolism is an extremely rare complication that can follow gastrointestinal endoscopy. The most accepted treatment of cerebral air embolism (CAE) is hyperbaric oxygen (HBO). Limited evidence suggests that lidocaine may have a neuroprotective effect. The exact mechanism does not appear to be well elucidated.
Source: Journal of Stroke and Cerebrovascular Diseases - September 26, 2019 Category: Neurology Authors: Malik Ghannam, Azizullah Beran, Dana Ghazaleh, Tanner Ferderer, Brent Berry, Mona Al Banna, Leighton Mohl, Christopher Streib, Tapan Thacker, Ivan Matos Source Type: research

Carotid Webs in Cryptogenic Ischemic Strokes: A Matched Case-Control Study
Background: Young individuals with symptomatic carotid webs may be predisposed to ischemic strokes. However, evidence remains scarce. This investigation reports the frequency of carotid webs among patients with cryptogenic strokes compared to a control group. Methods: Consecutive cryptogenic ischemic strokes and trauma patients were identified. Additional inclusion criteria required age 18-60 years and availability of head/neck computed tomography (CT) angiography. CT angiogram (CTA) neck images were evaluated independently by 2 fellowshiptrained specialists.
Source: Journal of Stroke and Cerebrovascular Diseases - September 26, 2019 Category: Neurology Authors: Song J. Kim, Jason W. Allen, Mehdi Bouslama, Fadi Nahab, Michael R. Frankel, Raul G. Nogueira, Diogo C. Haussen Source Type: research

Neuroprotective Effects and Mechanisms of Zhenlong Xingnao Capsule in In Vivo and In Vitro Models of Hypoxia
In this study, we determined the in vitro and in vivo effects of ZXC on reactive oxygen species (ROS) in a mouse BV-2 microglial cell hypoxia-reoxygenation and rat middle cerebral artery occlusion infarction models. We aimed to clarify the role of ZXC in cerebral ischemia protection; reveal amino acid neurotransmitter changes in the frontal cortex after drug intervention; determine mRNA and protein expression changes in Bcl-2, Bax, caspase-3, P38, and nuclear factor (NF)-кB in the frontal cortex and changes in antioxidant indices in the brain; and elucidate the mechanisms underlying ZXC action. After hypoxia-reoxygenation...
Source: Frontiers in Pharmacology - September 26, 2019 Category: Drugs & Pharmacology Source Type: research

Impact of Cerebral Perfusion on Outcomes of Aortic Surgery: STS Adult Cardiac Database Analysis.
CONCLUSIONS: For patients without dissection and requiring >30 minutes circulatory arrest, optimal cerebral protection strategies are deep hypothermia with either antegrade or retrograde cerebral perfusion; or moderate hypothermia with antegrade cerebral perfusion. PMID: 31563489 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - September 26, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Itagaki S, Chikwe J, Sun E, Chu D, Toyoda N, Egorova N Tags: Ann Thorac Surg Source Type: research

Long-Term Single Centre Outcomes of Patients with Chronic Renal Dialysis Undergoing Cardiac Surgery.
CONCLUSIONS: Cardiac surgery in DD-CRF patients is associated with high morbidity and mortality. Interestingly, overall mortality was mainly none cardiac-related, where elderly patients or those presented with CHF had the worst life expectancy. However, subsequent kidney transplantation positively impact long-term survival in such patients. PMID: 31563486 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - September 26, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Mourad F, Cleve N, Nowak J, Wendt D, Sander A, Demircioglu E, El Gabry M, Jakob H, Shehada SE Tags: Ann Thorac Surg Source Type: research

Poor Outcome of Surgical Management of Acute Malfunctioning Mechanical Mitral Valve During Pregnancy. Should Centers with Limited Resources Find Different Options?
CONCLUSION: Acute malfunctioning MHV during pregnancy represents a real dilemma to patients and caregivers. It carries high fetal and maternal morbidity and mortality, especially in centers with limited resources. We believe that an alternative plane must be formulated for such patients to avoid devastating complications, including maternal and fetal deaths. PMID: 31596721 [PubMed - in process]
Source: The Heart Surgery Forum - September 26, 2019 Category: Cardiovascular & Thoracic Surgery Authors: Elsayed AAA, Abdelaal KM, Abdelghaffar AMM, Mohamed EEH, Mahran TMA, Ahmed MSM, Ibrahim AM, Mansour AA Tags: Heart Surg Forum Source Type: research

Effectiveness of Only Aspirin or Clopidogrel Following Percutaneous Left Atrial Appendage Closure
Percutaneous left atrial appendage closure (LAAC) offers a feasible option for stroke prevention in patients with atrial fibrillation (AF), but the optimal antithrombotic treatment strategy for patients with strict contraindications to oral anticoagulation (OAC) remains uncertain. We sought to evaluate short- and long-term outcome after percutaneous LAAC in these very patients discharged on single antiplatelet therapy (SAPT) alone. All consenting AF patients who underwent LAAC from February 2009 to August 2018 in Turku University Hospital, Finland, were enrolled into a prospectively maintained registry.
Source: The American Journal of Cardiology - September 26, 2019 Category: Cardiology Authors: Jussi-Pekka Pouru, Samuli Jaakkola, Juha Lund, Fausto Biancari, Antti Saraste, K. E. Juhani Airaksinen Source Type: research

Predictors of clinically important changes in actual and perceived functional arm use of the affected upper limb after rehabilitative therapy in chronic stroke
To identify the predictors of minimal clinically important changes in actual and perceived functional arm use of the affected upper limb after rehabilitative therapy.
Source: Archives of Physical Medicine and Rehabilitation - September 26, 2019 Category: Rehabilitation Authors: Yi-chun Li, Wan-wen Liao, Yu-wei Hsieh, Keh-chung Lin, Chia-ling Chen Source Type: research

Treatment of Extracranial Arterial Dissection: the Roles of Antiplatelet Agents, Anticoagulants, and Stenting
AbstractPurpose of reviewCervicocephalic arterial dissection (CeAD) is the most commonly identified cause of stroke in young healthy individuals. The management of acute ischemic stroke due to the diagnosed or suspected CeAD is well established and is appropriate for thrombolysis. There is a substantial risk of stroke recurrence in the early post-stroke period. The optimum method of stroke prevention in the subacute period remains debatable. In our review, we focused on the management of recurrent stroke in CeAD, the choice of various antithrombotic agents for stroke risk reduction with regard to specific pathogenetic mech...
Source: Current Treatment Options in Neurology - September 26, 2019 Category: Neurology Source Type: research

Assessing gender identity differences in cardiovascular disease in US adults: an analysis of data from the 2014 –2017 BRFSS
AbstractThe purpose of this study was to assess gender identity differences in CVD risk and CVD conditions among adults in the U.S. Using data from the 2014 –2017 BRFSS we compared CVD risk and CVD conditions in gender minorities (transgender men, transgender women and gender nonconforming persons) to both cisgender men and women. The sample consisted of 662,903 participants. Transgender women (AOR 1.34, 95% CI 1.05–1.72) and transgender men (AOR 1. 54, 95% CI 1.07–2.24) were more likely to be overweight than cisgender women. Compared to cisgender women, transgender women reported higher rates of diabetes (AOR 1.45, ...
Source: Journal of Behavioral Medicine - September 26, 2019 Category: Psychiatry Source Type: research

Misconceptions regarding the adequacy of best medical intervention alone for asymptomatic carotid stenosis
Medical intervention (risk factor identification, lifestyle coaching, and medication) for stroke prevention has improved significantly. It is likely that no more than 5.5% of persons with advanced asymptomatic carotid stenosis (ACS) will now benefit from a carotid procedure during their lifetime. However, some question the adequacy of medical intervention alone for such persons and propose using markers of high stroke risk to intervene with carotid endarterectomy (CEA) and/or carotid angioplasty/stenting (CAS).
Source: Journal of Vascular Surgery - September 26, 2019 Category: Surgery Authors: Anne L. Abbott, Alejandro M. Brunser, Athanasios Giannoukas, Robert E. Harbaugh, Timothy Kleinig, Simona Lattanzi, Holger Poppert, Tatjana Rundek, Saeid Shahidi, Mauro Silvestrini, Raffi Topakian Source Type: research

Ultrasound Detection of Abnormal Cerebrovascular Morphology in a Mouse Model of Sickle Cell Disease Based on Wave Reflection
Sickle cell disease (SCD) is associated with a high risk of stroke, and affected individuals often have focal brain lesions termed silent cerebral infarcts. The mechanisms leading to these types of injuries are at present poorly understood. Our group has recently demonstrated a non-invasive measurement of cerebrovascular impedance and wave reflection in mice using high-frequency ultrasound in the common carotid artery. To better understand the pathophysiology in SCD, we used this approach in combination with micro-computed tomography to investigate changes in cerebrovascular morphology in the Townes mouse model of SCD.
Source: Ultrasound in Medicine and Biology - September 26, 2019 Category: Radiology Authors: Lindsay S. Cahill, Jesper Pilmeyer, Lisa X. Yu, Joe Steinman, Gregory M.T. Hare, Andrea Kassner, Christopher K. Macgowan, John G. Sled Tags: Original Contribution Source Type: research

Strokectomy and Extensive Cisternal CSF Drain for Acute Management of Malignant Middle Cerebral Artery Infarction: Technical Note and Case Series
Conclusion: Supratentorial strokectomy seems to be safe and could be a potential alternative to decompressive craniectomy for the acute management of malignant MCA stroke. Advantages of this approach could be low complication rate, avoidance of bone reconstruction procedure, and reduced occurrence of hydrocephalus or seizures. A co-operative multicentric, prospective pilot study will be necessary to validate this technical approach.
Source: Frontiers in Neurology - September 26, 2019 Category: Neurology Source Type: research

Predictive value of the THRIVE score for outcome in patients with acute basilar artery occlusion treated with thrombectomy
ConclusionsA high THRIVE score was independently associated with an increased risk of poor functional outcome and all ‐cause mortality in AIS patients with BAO who underwent thrombectomy treatment. Moreover, the THRIVE score appeared to be a better predictor of clinical outcome than the NIHSS score.
Source: Brain and Behavior - September 26, 2019 Category: Neurology Authors: Beilei Chen, Liu Yang, Jing Hang, Shoujiang You, Jun Li, Xiaobo Li, Liangzhu Wang, Li Jiang, Wei Li, Hailong Yu Tags: ORIGINAL RESEARCH Source Type: research

The importance of fluid balance in critically ill patients - a retrospective observational study.
CONCLUSION: A positive fluid balance exceeding 1000 mls in the first 72 hours after ICU admission is independently associated with an increased risk of mortality in critically ill patients with cardiovascular disorders. The use of colloid solutions is associated with a higher positive fluid balance. PMID: 31564714 [PubMed - as supplied by publisher]
Source: Polish Heart Journal - September 26, 2019 Category: Cardiology Authors: Trejnowska E, Skoczyński S, Armatowicz P, Knapik M, Kurdyś P, Ślusarz K, Tarzyńska-Słomian M, Knapik P Tags: Kardiol Pol Source Type: research

How Accurate Are the Stroke Severity Scales for Identifying Large Vessel Occlusions?
Publication date: Available online 24 September 2019Source: Annals of Emergency MedicineAuthor(s): Latha Ganti, J. Adam Oostema
Source: Annals of Emergency Medicine - September 25, 2019 Category: Emergency Medicine Source Type: research

Gum Disease May Raise Hypertension Risk
People with gum disease tended to have higher blood pressure, increasing their risk of heart disease and stroke.
Source: NYT Health - September 25, 2019 Category: Consumer Health News Authors: Nicholas Bakalar Tags: Blood Pressure Gums (Mouth) Hypertension Heart Source Type: news

New Data on Antiepileptic Drugs and Birth Defects New Data on Antiepileptic Drugs and Birth Defects
Dr Christoph Diener discusses important new studies on epilepsy, headache, and stroke.Medscape Neurology
Source: Medscape Neurology and Neurosurgery Headlines - September 25, 2019 Category: Neurology Tags: Neurology & Neurosurgery Commentary Source Type: news

Poststroke Fatigue Is Related to Motor and Cognitive Performance: A Secondary Analysis
Conclusions: Functional gait, balance, and cognitive performance are associated with PSF. Fatigue should be considered when planning and delivering interventions for individuals with stroke. Future studies are needed to explore the potential efficacy of balance and cognitive training in PSF management. Video Abstract available for more insights from the authors (see Video, Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A287).
Source: Journal of Neurologic Physical Therapy - September 25, 2019 Category: Physiotherapy Tags: Research Articles Source Type: research

Outcome of Anticoagulation Therapy of Left Atrial Thrombus or Sludge in Patients With Nonvalvular Atrial Fibrillation or Flutter.
CONCLUSIONS: Compared with warfarin, dabigatran and rivaroxaban can also effectively resolve LA thrombus or sludge with no significant differences. Increasing the duration of anticoagulation, determining the optimal dosage of anticoagulants, and switching to another anticoagulant when necessary could be considered to improve treatment effectiveness. PMID: 31543101 [PubMed - in process]
Source: The American Journal of the Medical Sciences - September 25, 2019 Category: General Medicine Authors: Yang Y, Du X, Dong J, Ma C Tags: Am J Med Sci Source Type: research

PATH-s: Predictive Validation of a Caregiving Preparedness Assessment Tool at 90-Days Post-Discharge from an IRF
The Preparedness Assessment for the Transition Home after Stroke (PATH-s) was developed to assess caregiver preparedness and provide actionable data for treatment planning. This is a follow-up study on the convergent and predictive validity of the PATH-s.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Michelle Camicia, Barbara Lutz, Brian Theodore Source Type: research

Contralesional White Matter Integrity May Predict Response To Upper Limb Task-Specific Training In Chronic Stroke
To investigate the neuroanatomical correlates of upper limb recovery following task-specific training.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Daniela Mattos, Xin Hong, Jerrel Rutlin, Joshua Shimony, Alexandre Carter Source Type: research

Using the ICF to Classify and Describe the Problems Care Partner Face During Inpatient Rehabilitation
To use the International Classification of Functioning (ICF) standardized linking technique to classify and describe care-partner challenges reported during a Problem Solving Training (PST) intervention  in care-partners of adults with traumatic injury or stroke during care-recipients' hospital stay.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Candice Osborne, Chung Lin (Novelle) Kew, Andrew Nabasny, Shannon Juengst Source Type: research

A Pilot Inpatient Tele-Consult Program For Vision Rehabilitation
Determine if patients with signs and symptoms of strabismus (eye misalignment) can be diagnosed and treated with press-on prism using a tele-consult process. Strabismus occurs in 20% of stroke survivors, increases risk for fall by 2.2x ’s, and can be successfully and inexpensively treated with press-on prism in a reported 64% to 80%. Unfortunately care is often delayed due to a lack of access to vision rehabilitation specialists (OD).
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Gang Luo, Matthew Keilty, Kevin Houston Source Type: research

A Latent Profile Analysis of the NIH Toolbox Motor Battery in Persons With Neurological Disorders
To identify distinct motor function profiles among persons with spinal cord injury (SCI), traumatic brain injury (TBI), and stroke.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Rina Fox, Noelle Carlozzi, Allen Heinemann, David Tulsky, Richard Gershon Source Type: research

Inflamatory Leaching of Cerebral Tissue of Damaged Vascular Brain Regions by Monomeric C-Reactive Protein
Ourselves and others have previously shown the importance of mCRP in the induction of inflammation and in addition, the prevalence of the monomeric C-reactive protein (mCRP) form in the brains of individuals with dementia, after ischaemic stroke and following other brains vascular damage or degeneration.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Raid Al Baradie, Fuzail Ahmad Source Type: research

Impact of Participation in Therapy 7 Days per Week in an Inpatient Rehabilitation Stroke Population
To investigate the impact of increasing participation in mobility-based therapy for an additional two days per week on length of stay in an inpatient rehabilitation facility (IRF).
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Christine Davidson, Karen Ramsay, Jose Dominguez Source Type: research

Gait Pattern Analysis And Clinical Subgroup Identification: A Retrospective Observational Study
To identify basic gait features and abnormal gait patterns that are common to different neurological or musculoskeletal conditions, such as cerebral stroke, Parkinsonian disorders, radiculopathy, and musculoskeletal pain.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Dahyun Ahn, Dae Hyun Kim Source Type: research

Feasibility and Estimated Change in Post-Stroke Sedentary Behavior Attributed to ABLE
To assess feasibility (reliability, acceptability, tolerability, and safety) of ABLE through pre-established benchmarks, and to estimate change in sedentary behavior over time.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Emily Kringle, Lauren Terhorst, Grace Campbell, Bethany Barone Gibbs, Michael McCue, Elizabeth Skidmore Source Type: research

Families' Perceptions of FES as an Upper Limb Intervention for Young Children With Hemiparesis
To explore families ’ perceptions of the feasibility and outcomes of FES as an upper limb intervention for young children with hemiparesis due to a perinatal stroke.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Kristin Musselman, Emma Swaffield, Jaynie Yang, Patricia Manns Source Type: research

Pharyngeal Residue and Swallowing Treatment Recommendations After Stroke
To determine the degree of association between area of pharyngeal residue and swallow screen and ordinal pharyngeal residue rating, as well as the extent to which these measures drive therapy recommendations.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Rachel Mulheren, Marlis Gonzalez-Fernandez Source Type: research

Stroke Unit Nursing Care Process Quality Improvement Study
To determine whether nursing staff could quickly improve knowledge of important evidence based research.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: David Burke, Tracie McCargo, Gina Bell Source Type: research

Protracted Recovery From Stroke-Like Migraine Attacks After Radiation Therapy (SMART) Syndrome: A Case Report
The purpose of this case report is to document a protracted course of recovery and the deficits exhibited by a person with SMART syndrome.
Source: Archives of Physical Medicine and Rehabilitation - September 25, 2019 Category: Rehabilitation Authors: Cyrielle Andrew, Karen Hux Source Type: research