The Coronavirus Pandemic - At the Beginning of the Learning Curve.
PMID: 32709279 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - July 29, 2020 Category: General Medicine Authors: Perez RL, Roman J Tags: Am J Med Sci Source Type: research

Umbilical Vein Recanalization.
PMID: 32713510 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - July 10, 2020 Category: General Medicine Authors: Michaud M, Ranaivojaona S, Livideanu C, Mery C, Gaches F Tags: Am J Med Sci Source Type: research

Implementation of Protocolized Medicine: Management of Hyperkalemia on the Inpatient Internal Medicine Floors.
PMID: 32713509 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - July 6, 2020 Category: General Medicine Authors: Sarwal A, Gomez E, Mon AM, Gnanasekaran I, Menon V, Venugopal U, Kasubhai M Tags: Am J Med Sci Source Type: research

Heart Failure With Mid-Range Ejection Fraction - The "Middle" Child of the Heart Failure Siblings.
Heart Failure With Mid-Range Ejection Fraction - The "Middle" Child of the Heart Failure Siblings. Am J Med Sci. 2020 Jul;360(1):1-2 Authors: Adebayo A, Panjrath G PMID: 32620218 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - July 1, 2020 Category: General Medicine Authors: Adebayo A, Panjrath G Tags: Am J Med Sci Source Type: research

Southern Society for Clinical Investigation Nephrology Young Investigators' Forum.
PMID: 32620219 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - July 1, 2020 Category: General Medicine Authors: McCann S Tags: Am J Med Sci Source Type: research

A Comprehensive Review of Manifestations of Novel Coronaviruses in the Context of Deadly COVID-19 Global Pandemic.
Abstract Since December 2019, the global pandemic caused by the highly infectious novel coronavirus 2019-nCoV (COVID-19) has been rapidly spreading. As of April 2020, the outbreak has spread to over 210 countries, with over 2,400,000 confirmed cases and over 170,000 deaths.1 COVID-19 causes a severe pneumonia characterized by fever, cough and shortness of breath. Similar coronavirus outbreaks have occurred in the past causing severe pneumonia like COVID-19, most recently, severe acute respiratory syndrome coronavirus (SARS-CoV) and middle east respiratory syndrome coronavirus (MERS-CoV). However, over time, SARS-C...
Source: The American Journal of the Medical Sciences - July 1, 2020 Category: General Medicine Authors: Gulati A, Pomeranz C, Qamar Z, Thomas S, Frisch D, George G, Summer R, DeSimone J, Sundaram B Tags: Am J Med Sci Source Type: research

Effect of ABO Blood Groups on the Response to Warfarin.
CONCLUSIONS: Our study showed that patients with non-O blood groups require higher doses of warfarin. PMID: 32620221 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - July 1, 2020 Category: General Medicine Authors: Zou S, Wu L, Chen Z, Li X, Chen H, Tan X, Yu M Tags: Am J Med Sci Source Type: research

Pneumomediastinum Related to Covid-19 Pneumonia.
PMID: 32605714 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - June 6, 2020 Category: General Medicine Authors: Romano N, Fischetti A, Melani EF Tags: Am J Med Sci Source Type: research

The Coronavirus Pandemic - Lessons Learned?
PMID: 32605713 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - June 3, 2020 Category: General Medicine Authors: Roman J Tags: Am J Med Sci Source Type: research

Orthodox Judaism as a Risk Factor of Covid-19 in Israel.
PMID: 32591092 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - June 1, 2020 Category: General Medicine Authors: Schattner A, Klepfish A Tags: Am J Med Sci Source Type: research

Does the Impact of COVID-19 Improve the Doctor-Patient Relationship in China?
PMID: 32563570 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - June 1, 2020 Category: General Medicine Authors: Gao B, Dong J Tags: Am J Med Sci Source Type: research

Why Did the Original Jones Criteria Not Emphasize Streptococcal Infection?
PMID: 32498940 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - June 1, 2020 Category: General Medicine Authors: Shulman ST Tags: Am J Med Sci Source Type: research

Prognostic and Clinicopathological Value of PD-L1 in Melanoma: A Meta-Analysis.
CONCLUSIONS: Positive PD-L1 expression may be an important prognostic factor for longer OS in patients with metastatic melanoma. PMID: 32498941 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - June 1, 2020 Category: General Medicine Authors: Xu J, Wang F, Yan Y, Zhang Y, Du Y, Sun G Tags: Am J Med Sci Source Type: research

Relationship Between Particulate Matter (PM2.5) and Hospitalizations and Mortality of Chronic Obstructive Pulmonary Disease Patients: A Meta-Analysis.
CONCLUSIONS: PM2.5 is associated with COPD hospitalizations and mortality. Controlling ambient air pollution would provide benefits to COPD patients. PMID: 32498942 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - June 1, 2020 Category: General Medicine Authors: Zhu RX, Nie XH, Chen YH, Chen J, Wu SW, Zhao LH Tags: Am J Med Sci Source Type: research

MicroRNA-294 Promotes Cell Proliferation, Migration and Invasion in SMMC-7721 Hepatoma Carcinoma Cells by Activating the JNK/ERK Signaling Pathway.
CONCLUSIONS: miR-294 is important for the development of HCC in terms of the biological activities of cells, and may be a novel therapeutic target for HCC. PMID: 32498943 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - June 1, 2020 Category: General Medicine Authors: Cheng X, Chen M, Liu Z Tags: Am J Med Sci Source Type: research

EGFR-Negative Miliary Mets: A Poor Prognostic Entity.
PMID: 32487326 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - May 19, 2020 Category: General Medicine Authors: Akella P, Gogtay M Tags: Am J Med Sci Source Type: research

What Is the Next Step in a Patient With an Undiagnosed Exudative Pleural Effusion?
PMID: 32482349 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - May 13, 2020 Category: General Medicine Authors: Nugent K, Berdine G, Test V Tags: Am J Med Sci Source Type: research

COVID-19 Retesting in the Primary Care Setting.
PMID: 32448499 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - May 12, 2020 Category: General Medicine Authors: Summer AK, Summer RS, Solga SF, Spacek LA Tags: Am J Med Sci Source Type: research

Megacolon Complicating Ulcerative Colitis and Clostridiodes Infection.
PMID: 32448498 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - May 11, 2020 Category: General Medicine Authors: Apostolov R, Nicolaides S, Vasudevan A Tags: Am J Med Sci Source Type: research

Hyperleukocytosis, Artifactual Hypoglycemia, and Massive Hepato-Splenomegaly: A Case of Chronic Myelogenous Leukemia.
PMID: 32448496 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - May 5, 2020 Category: General Medicine Authors: Ghrewati M, Singh B, Maroules M Tags: Am J Med Sci Source Type: research

Nonalcoholic Fatty Liver Disease Associated With Bladder Cancer.
Abstract BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is regarded as a feature of metabolic syndrome in the liver. Metabolic syndrome is associated with a higher risk of bladder cancer. However, the association between NAFLD and bladder cancer is unclear. We aimed to investigate the association between NAFLD and bladder cancer. MATERIALS AND METHODS: The records of all patients (n = 251) diagnosed with the bladder cancer in our hospital between 2009 and 2013 were reviewed. We also randomly collected the records of adults without cancer (n = 266) as the control group. Clinical chara...
Source: The American Journal of the Medical Sciences - May 4, 2020 Category: General Medicine Authors: Chiang CL, Huang HH, Huang TY, Shih YL, Hsieh TY, Lin HH Tags: Am J Med Sci Source Type: research

Quantifying the Economic Burden of Acute Myocardial Infarction: A Timely and Important Concept.
PMID: 32359532 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - May 1, 2020 Category: General Medicine Authors: Berman AE, Miller DD Tags: Am J Med Sci Source Type: research

Five-Year Glycemic Trajectories Among Healthy African-American and European-American Offspring of Parents With Type 2 Diabetes.
CONCLUSIONS: During 5 years of follow-up, black and white offspring of parents with T2DM exhibited remarkable phenotypic concordance of glycemic trajectories. Thus, parental history of T2DM may be a stronger factor than race/ethnicity in the prediction of longitudinal glycemic trends. PMID: 32359533 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - May 1, 2020 Category: General Medicine Authors: Razavi LN, Ebenibo S, Edeoga C, Wan J, Dagogo-Jack S Tags: Am J Med Sci Source Type: research

WASF3 Knockdown Sensitizes Gastric Cancer Cells to Oxaliplatin by Inhibiting ATG12-Mediated Autophagy.
CONCLUSIONS: Our analysis demonstrates WASF3 targeting is a new potential therapeutic strategy for gastric cancer. PMID: 32359534 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - May 1, 2020 Category: General Medicine Authors: Nie Y, Liang X, Liu S, Guo F, Fang N, Zhou F Tags: Am J Med Sci Source Type: research

Enhanced Frequency of CD19+IL-10+B Cells in Human Gastric Mucosa Infected by Helicobacter pylori.
Abstract BACKGROUND: CD19+IL-10+B cells are considered as a particular subset of immunosuppressive cells by producing interleukin 10 (IL-10), which plays an important role in infectious and autoimmune diseases. The aim of this study was to determine the number of CD19+IL-10+B cells in Helicobacter pylori (H. pylori) positive patients in comparison with H. pylori negative patients, and to determine the association with different clinical outcomes, such as gastritis and peptic ulcer disease (PUD), in infected patients. METHODS AND MATERIALS: We studied 25 infected patients with gastritis, 25 infected patients w...
Source: The American Journal of the Medical Sciences - April 5, 2020 Category: General Medicine Authors: Nahid-Samiei M, Rahimian G, Shafigh M, Taheri F, Karami-Hurestani M, Sanaei MJ, Heshmati M, Bagheri N Tags: Am J Med Sci Source Type: research

A Complete Triad: Horner's Syndrome in Tuberculous Meningitis.
PMID: 32317170 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - April 5, 2020 Category: General Medicine Authors: Bongomin F, Khan SA, Oravec T Tags: Am J Med Sci Source Type: research

A Fatal Case of Thrombotic Microangiopathy Without Schistocytosis and Absent Biochemical Markers of Hemolysis.
Abstract Thrombotic microangiopathy (TMA) is characterized by microangiopathic hemolytic anemia with thrombocytopenia. In addition to the primary TMA syndromes, microangiopathic hemolytic anemia with thrombocytopenia can be seen in many systemic diseases. Transplant associated TMA (TA-TMA) affects patients following stem cell or solid organ transplant. A 48-year-old male who underwent autologous stem cell transplant for nonsecretory multiple myeloma was admitted to our hospital with worsening anemia, thrombocytopenia, renal dysfunction and hepatosplenomegaly. Initial blood work revealed rare schistocytes and norma...
Source: The American Journal of the Medical Sciences - April 5, 2020 Category: General Medicine Authors: Saha BK, Saha A, Chong W, Beegle S Tags: Am J Med Sci Source Type: research

Acarbose versus Repaglinide in Diabetes Treatment: A New Appraisal of Two Old Rivals.
Abstract BACKGROUND: Acarbose and repaglinide are two safe and effective antidiabetic agents that are especially in wide use in Asian and Middle Eastern countries. These two prandial agents share some outstanding qualities that their newer counterparts do not. While globally available in generic versions, both are oral and cheap. There is a paucity of data regarding their comparative efficacy. Herein, a head-to-head comparison of the efficacy of the two in treatment of postprandial hyperglycemia of newly-diagnosed type 2 diabetes was investigated. MATERIALS AND METHODS: One hundred and sixty-four newly-diagno...
Source: The American Journal of the Medical Sciences - March 25, 2020 Category: General Medicine Authors: Pishdad R, Pishdad P, Pishdad GR Tags: Am J Med Sci Source Type: research

Identification of Hub Genes and Analysis of Prognostic Values in Hepatocellular Carcinoma by Bioinformatics Analysis.
CONCLUSIONS: The present study identified hub genes and pathways in HCC that may be potential targets for diagnosis, treatment and prognostic prediction. PMID: 32200915 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - March 25, 2020 Category: General Medicine Authors: Xu L, Tong T, Wang Z, Qiang Y, Ma F, Ma X Tags: Am J Med Sci Source Type: research

E-cigarettes and Vaping Associated Lung Injury: A Case Series and Brief Review.
PMID: 32089155 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - February 26, 2020 Category: General Medicine Authors: Hilton R, Summer R, Roman J, Sundaram B, George G Tags: Am J Med Sci Source Type: research

Exercise Capacity and Ventilatory Efficiency in Patients With Pulmonary Embolism After Short Duration of Anticoagulation Therapy.
Abstract BACKGROUND: Although anticoagulation therapy can reduce the risk for pulmonary embolism (PE) recurrence, symptoms such as exertional dyspnea or pain can persist for several months to years. Therefore, we aimed to assess the improvement of ventilatory efficiency and exercise capacity during cardiopulmonary exercise test in PE patients after short duration of anticoagulant therapy. MATERIALS AND METHODS: Pulmonary function testing, arterial blood gas analysis and cardiopulmonary exercise test were performed in 30 PE patients after anticoagulant therapy of 4 weeks (early phase) and after 6 months (late ...
Source: The American Journal of the Medical Sciences - February 26, 2020 Category: General Medicine Authors: Huang D, Guo J, Yang W, Liu J Tags: Am J Med Sci Source Type: research

Different Statin Effects of ST-elevation Versus Non-ST-Elevation Acute Myocardial Infarction After Stent Implantation.
CONCLUSIONS: Statin therapy was more effective in reducing the cumulative risks of MACE, all-cause death, and TVR in the STEMI group than NSTEMI group in Korean patients with AMI after successful drug-eluting stent implantation. PMID: 32089157 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - February 26, 2020 Category: General Medicine Authors: Kim YH, Her AY, Jeong MH, Kim BK, Hong SJ, Kim S, Ahn CM, Kim JS, Ko YG, Choi D, Hong MK, Jang Y Tags: Am J Med Sci Source Type: research

The Characteristics of Intestinal-Barrier Damage in Rats With IgA Nephropathy.
In this study, we explored the characteristics of the intestinal barrier in rats with IgAN. MATERIALS AND METHODS: We randomly divided 17 Sprague Dawley (SD) male rats into a normal control group (NC; n = 9) and an IgAN model group (n = 8). Feces in the distal ileum were taken for intestinal-microbiota 16sDNA sequencing. We also took a segment of terminal ileum to analyze intestinal morphology and to detect mRNA and protein expression of the tight-junction proteins zonula occludens-1 (ZO-1) and occludin (OCLN), as well as of mucin 2 (MUC2). We then measured levels of serum diamine oxidase (DAO) and D-lactic ac...
Source: The American Journal of the Medical Sciences - February 26, 2020 Category: General Medicine Authors: Zhou N, Shen Y, Fan L, Sun Q, Huang C, Hao J, Lan J, Yan H Tags: Am J Med Sci Source Type: research

Arterial Complications Associated With Renal Cell Carcinoma.
PMID: 32089159 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - February 26, 2020 Category: General Medicine Authors: Hua J, Pointer D, Silberstein J, Sam AD Tags: Am J Med Sci Source Type: research

Effect of Using the Rapid Shallow Breathing Index as Readiness Criterion for Spontaneous Breathing Trials in a Weaning Protocol.
CONCLUSIONS: The inclusion of the RSBI in a readiness screen may not be useful in a weaning protocol. PMID: 32039763 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - February 1, 2020 Category: General Medicine Authors: Figueroa-Casas JB, Montoya R, Garcia-Blanco J, Lehker A, Hussein AM, Abdulmunim H, Kabbach G, Mahfoud A Tags: Am J Med Sci Source Type: research

Ivermectin Augments the In Vitro and In Vivo Efficacy of Cisplatin in Epithelial Ovarian Cancer by Suppressing Akt/mTOR Signaling.
CONCLUSIONS: Our work suggests that ivermectin may be a useful addition to the treatment armamentarium for ovarian cancer and that targeting Akt/mTOR signaling is a therapeutic strategy to increase chemosensitivity in ovarian cancer. PMID: 32039764 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - February 1, 2020 Category: General Medicine Authors: Zhang X, Qin T, Zhu Z, Hong F, Xu Y, Zhang X, Xu X, Ma A Tags: Am J Med Sci Source Type: research

The AJMS in the Beginning-Nathaniel Chapman, William Osler, and the Philadelphia Story.
PMID: 32039765 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - February 1, 2020 Category: General Medicine Authors: Mangione S Tags: Am J Med Sci Source Type: research

How American Medicine Got to This Place.
PMID: 32039766 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - February 1, 2020 Category: General Medicine Authors: deShazo RD Tags: Am J Med Sci Source Type: research

TGF- β and Diabetic Nephropathy: Lessons Learned Over the Past 20 Years.
TGF-β and Diabetic Nephropathy: Lessons Learned Over the Past 20 Years. Am J Med Sci. 2020 Feb;359(2):70-72 Authors: Gewin LS PMID: 32039767 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - February 1, 2020 Category: General Medicine Authors: Gewin LS Tags: Am J Med Sci Source Type: research

Feasibility and Reliability of Rapid Diagnosis of Myocardial Infarction.
CONCLUSION: Standard CK-MB mass measurements within 9 hours of arrival provided an accurate clinical assessment in> 99% of the cases. The high sensitivity and negative predictive values suggest that early diagnosis of myocardial infarction is feasible and reliable. PMID: 32039768 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - February 1, 2020 Category: General Medicine Authors: Engel G, Rockson SG Tags: Am J Med Sci Source Type: research

Transcriptional Regulation of Transforming Growth Factor β1 by Glucose: Investigation into the Role of the Hexosamine Biosynthesis Pathway.
CONCLUSIONS: The metabolism of glucose through the HBP mediates extracellular matrix production, possibly via the stimulation of TGF-β in kidney cells. Hexosamine metabolism therefore, may play a role in the development of diabetic nephropathy. PMID: 32039769 [PubMed - in process] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - February 1, 2020 Category: General Medicine Authors: Daniels MC, McClain DA, Crook ED Tags: Am J Med Sci Source Type: research

Renal Lipid Metabolism and Lipotoxicity in Diabetes.
Abstract The pathogenesis of diabetic kidney disease is a complex process caused by both glucotoxicity and lipotoxicity due to lipid accumulation. In cases of diabetic animals, lipid deposition is found in both tubular and glomerular portions of the kidneys, which are the major sites of diabetic nephropathy lesions. The aim of this review was to provide insights into the mechanisms that lead to the development of renal lipid accumulation and the effects of renal lipotoxicity in the diabetic condition. An increased number of lipogenic genes and a decreased number of lipid oxidation genes are also detected in diabet...
Source: The American Journal of the Medical Sciences - February 1, 2020 Category: General Medicine Authors: Thongnak L, Pongchaidecha A, Lungkaphin A Tags: Am J Med Sci Source Type: research

Pulmonary Artery Pseudoaneurysm Caused by Lung Abscess.
PMID: 32014303 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - January 16, 2020 Category: General Medicine Authors: Saito S, Kadota T, Gochi M Tags: Am J Med Sci Source Type: research

Acute Onset Hyperammonemic Encephalopathy Related to Fibrolamellar Carcinoma: Another One Bites the Dust.
PMID: 32014302 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - January 13, 2020 Category: General Medicine Authors: Surjan RCT, Silveira SP, Pinheiro JLS, Pinheiro PHS, Barros MFA, Soares SRP Tags: Am J Med Sci Source Type: research

Demethylation of Di-Methylation of Lysine 4 on Histone 3 Is Inhibited by General Control Nondepressible 5-Induced Acetylation of Lysine-Specific Demethylase 1.
CONCLUSIONS: GCN5-induced acetylation of LSD1 impeded progression of colon cancer by inhibiting the demethylation of histone. PMID: 31982102 [PubMed - as supplied by publisher] (Source: The American Journal of the Medical Sciences)
Source: The American Journal of the Medical Sciences - January 7, 2020 Category: General Medicine Authors: Jiao M, Xia L, Chen J, Cui Z Tags: Am J Med Sci Source Type: research

An Unexpected Case of Lagochilascariasis: Interdisciplinary Management and Use of 12S and 18S rDNA Analysis.
Abstract A Mexican 24-year-old male patient was referred to our hospital due to increased left retroauricular volume with skin fistulisation, resembling an infection by the uncommon worm Lagochilascaris minor. The patient was submitted to lateral skull base surgery. No adult worms or eggs were observed during light and scanning electron microscopy analysis, as well as by histopathologic examination of the small piece of removed tissue, only L3 stage larvae of Lagochilascaris spp. were identified. Polymerase chain reaction-sequencing assays were performed using primers for the mitochondrial 12S and the nuclear 18S ...
Source: The American Journal of the Medical Sciences - January 7, 2020 Category: General Medicine Authors: Martinez-Hernandez F, Prado-Calleros HM, Ramirez-Hinojosa JP, Figueroa-Angel V, Lopez-Reynoso MT, Jimenez-Andrade MDC, Estrada-Moscoso I, Rivas N, Escobedo-Ortegon J, Flisser A, Romero-Valdovinos MG, Maravilla P Tags: Am J Med Sci Source Type: research

Girolamo Fabrici d'Acquapendente and the Oplomochlion: The Several Applications of an Effective Rehabilitation Tool.
Abstract Girolamo Fabrici d'Acquapendente (1533-1619) was an Italian anatomist, surgeon and physiologist and a protagonist of the scientific revolution of the Renaissance. He made anatomy a scientific discipline and is justly considered a precursor of modern orthopaedics. He invented and used several external corrective devices for the treatment of congenital and acquired deformities of the limbs and spinal column, especially those following tubercular infection and rickets, torticollis, vertebral caries kyphosis, scoliosis, and rachitic deformities of the leg, but also congenital dislocation of the hip and congen...
Source: The American Journal of the Medical Sciences - January 1, 2020 Category: General Medicine Authors: Biz C, Brunati A, Belluzzi E, Ruggieri P, Masiero S, Rippa Bonati M Tags: Am J Med Sci Source Type: research

Uric Acid Level as a Predictor of Long-Term Mortality in Advanced Age Population.
Abstract BACKGROUND: Hyperuricemia is associated with the development, progression and outcome of several diseases. The purpose of this study is to evaluate the serum uric acid (UA) levels as a predictor of long-term mortality in an older population (age 60 years and above). MATERIALS AND METHODS: Patients older than 60 years who were hospitalized in the departments of geriatrics and internal medicine in Shaare Zedek Medical Center in Jerusalem during a period of 4 months (March-June 2014) were included in this observational study. Association between hyperuricemia and long-term mortality were analyzed using ...
Source: The American Journal of the Medical Sciences - January 1, 2020 Category: General Medicine Authors: Abu Sneineh M, Schwartz Y, Nesher G, Freier Dror Y, Breuer GS Tags: Am J Med Sci Source Type: research

The Potential Protective Effects of Diosmin on Streptozotocin-Induced Diabetic Cardiomyopathy in Rats.
Abstract BACKGROUND: Diabetic cardiomyopathy (DCM) is a nonischemic myocardial disorder characterized by metabolic disturbances and oxidative stress in diabetic patients. The present paper aims to determine the protective effect of the phlebotrophic drug, diosmin, on DCM in a model of high-fat diet-fed and streptozotocin-induced type 2 diabetes in the rat. MATERIALS AND METHODS: The animals were divided into 4 groups (8 rats/group) as follows: vehicle-treated nondiabetic control group, vehicle-treated diabetic group, diosmin (50 mg/kg)-treated diabetic group and diosmin (100 mg/kg)-treated diabetic group. Tre...
Source: The American Journal of the Medical Sciences - January 1, 2020 Category: General Medicine Authors: Ali TM, Abo-Salem OM, El Esawy BH, El Askary A Tags: Am J Med Sci Source Type: research

Pulmonary Mycobacterium Spindle Cell Pseudotumor in Patient With Liver Transplant.
We report a case of liver transplant patient who presented with lung masses, found to be Mycobacterium spindle cell pseudotumors. The masses demonstrated hypermetabolic activities on positron emission tomography. Core biopsy revealed sheets of spindle histiocytic cells with abundant acid-fast bacilli identified as Mycobacterium avium-intracellulare complex. This finding is a rare presentation of Mycobacterium infection, mainly nontuberculous Mycobaterium. It is characterized by a benign, spindle cell mass-forming reaction. Most of the reported cases had acquired immune deficiency syndrome or organ transplant. Histopatholog...
Source: The American Journal of the Medical Sciences - January 1, 2020 Category: General Medicine Authors: Chesdachai S, Udompap P, Li F, Lake JR, Kc M Tags: Am J Med Sci Source Type: research