Transcatheter or surgical aortic valve implantation in chronic dialysis patients: a German Aortic Valve Registry analysis
AbstractObjectivesThe aim of this study was to compare outcomes of transcatheter and surgical aortic valve implantation in chronic dialysis patients with aortic valve stenosis (AS).BackgroundChronic dialysis patients undergoing heart valve surgery are at higher risk for morbidity and mortality. Whether interventional techniques can reduce this risk is unclear because dialysis patients have thus far been excluded from randomized trials.MethodsChronic dialysis patients with AS enrolled in the German Aortic Valve Registry (GARY) between 2012 and 2015 were analyzed to compare transcatheter aortic valve implantation (TAVIn&thin...
Source: Clinical Research in Cardiology - September 23, 2020 Category: Cardiology Source Type: research

Letter to the editors referring to Fikenzer, S., Uhe, T., Lavall, D., Rudolph, U., Falz, R., Busse, M., Hepp, P., & amp; Laufs, U. (2020). Effects of surgical and FFP2/N95 face masks on cardiopulmonary exercise capacity. Clinical Research in Cardiology
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - September 23, 2020 Category: Cardiology Source Type: research

Factors associated with in-hospital mortality and adverse outcomes during the vulnerable post-discharge phase after the first episode of acute heart failure: results of the NOVICA-2 study
ConclusionsThe severity of decompensation and some baseline characteristics identified de novo AHF patients at increased risk of developing adverse outcomes during hospitalisation and the vulnerable post-discharge phase, without significant differences in these risk factors according to patient age at de novo AHF presentation.Graphic abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - September 21, 2020 Category: Cardiology Source Type: research

An unintentional complication during an intentional procedure —Sinus of Valsalva laceration during BASILICA
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - September 21, 2020 Category: Cardiology Source Type: research

A safe and simple technique for crossing stenotic aortic valves
ConclusionsThe pigtail/J-wire technique for AV crossing is safe, simple and fast. Primary placement of a pigtail catheter into the left ventricle at a success rate of 86% facilitates TAVI procedures. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - September 19, 2020 Category: Cardiology Source Type: research

Outcomes of acute coronary syndromes in coronavirus disease 2019
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - September 19, 2020 Category: Cardiology Source Type: research

Non-statin lipid-lowering therapy over time in very-high-risk patients: effectiveness of fixed-dose statin/ezetimibe compared to separate pill combination on LDL-C
AbstractBackgroundMany patients at very-high atherosclerotic cardiovascular disease risk do not reach guideline-recommended targets for LDL-C. There is a lack of data on real-world use of non-statin lipid-lowering therapies (LLT) and little is known on the effectiveness of fixed-dose combinations (FDC). We therefore studied prescription trends in oral non-statin LLT and their effects on LDL-C.MethodsA retrospective analysis was conducted of electronic medical records of outpatients at very-high cardiovascular risk treated by general practitioners (GPs) and cardiologists, and prescribed LLT in Germany between 2013 and 2018....
Source: Clinical Research in Cardiology - September 19, 2020 Category: Cardiology Source Type: research

Safety and effectiveness of coronary intravascular lithotripsy in eccentric calcified coronary lesions: a patient-level pooled analysis from the Disrupt CAD I and CAD II Studies
AbstractBackgroundThe aim of this study was to assess the safety and effectiveness of intravascular lithotripsy (IVL) in treating eccentric calcified coronary lesions.MethodsBetween December 2015 and March 2019, 180 patients were enrolled in the Disrupt CAD I and CAD II studies across 19 sites in 10 countries. Patient-level data were pooled from these two studies (n = 180), within which 47 eccentric lesions (26%) and 133 concentric lesions were identified.ResultsClinical success, defined as residual stenosis  
Source: Clinical Research in Cardiology - September 18, 2020 Category: Cardiology Source Type: research

Dual-axis rotational coronary angiography versus conventional coronary angiography: a randomized comparison
AbstractBackgroundDual-axis of rotational coronary angiography (RA), with one single cine acquisition during continuous C-arm motion along a pre-described path, is an alternative to conventional coronary angiography (CA). We assessed the performance of RA versus CA in a modern, experienced cath lab setting.MethodsSixty-seven patients with suspected coronary artery disease undergoing invasive coronary angiography were randomized to CA (n = 35) or dual-axis RA (n = 32). CA was performed with four left and two right coronary artery acquisitions with manual contrast medium injection. In RA, one cine...
Source: Clinical Research in Cardiology - September 16, 2020 Category: Cardiology Source Type: research

Echocardiography versus computed tomography and cardiac magnetic resonance for the detection of left heart thrombosis: a systematic review and meta-analysis
ConclusionsTTE is a fair alternative to DE-CMR for the identification of LV thrombi, while CT has a good accuracy compared to TEE for the detection of LAA thrombosis.PROSPERO registrationCRD42020185842. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - September 13, 2020 Category: Cardiology Source Type: research

Prognostic implications of pericardial and pleural effusion in patients with cardiac amyloidosis
ConclusionMore than 50% of patients with CA presented with pleural and/or pericardial effusions. While pleural effusion was clearly associated with poor RV function in AL, we were not able to detect this association with pericardial effusion. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - September 10, 2020 Category: Cardiology Source Type: research

Impact of real-time angiographic co-registered optical coherence tomography on percutaneous coronary intervention: the OPTICO-integration II trial
AbstractAimsLongitudinal geographic mismatch (LGM) as well as edge dissections are associated with an increased risk of adverse events after percutaneous coronary intervention (PCI). Recently, a novel system of real-time optical coherence tomography (OCT) with angiographic co-registration (ACR) became available and allows matched integration of cross-sectional OCT images to angiography. The OPTICO-integration II trial sought to assess the impact of ACR for PCI planning on the risk of LGM and edge dissections.MethodsA total of 84 patients were prospectively randomized to ACR-guided PCI, OCT-guided PCI (without co-registrati...
Source: Clinical Research in Cardiology - September 5, 2020 Category: Cardiology Source Type: research

Prognostic impact of atrial fibrillation in hypertrophic cardiomyopathy: a systematic review
ConclusionsAF is highly prevalent in patients with HCM. The presence of AF is associated with major adverse clinical outcomes. These findings suggest that both, aggressive screening and treatment of AF, are likely to have major prognostic impact on outcomes in HCM.Graphic abstractIncidence, prevalence and prognostic impact of AF in HCM. In this systematic review, AF incidence was 2.5 cases per-person years, prevalence was 22.3%. AF in HCM was associated with a seven-fold increased risk of thromboembolism, 2.8-fold increased risk of heart failure, 1.7-fold increased risk of sudden death and 2.5-fold increased risk of all-ca...
Source: Clinical Research in Cardiology - September 3, 2020 Category: Cardiology Source Type: research

Differential clinical impact of chronic total occlusion revascularization based on left ventricular systolic function
AbstractBackgroundThe effect of chronic total occlusion (CTO) revascularization on survival remains controversial. Furthermore, data regarding outcome differences for CTO revascularization based on left ventricular systolic function (LVSF) are limited.The differential outcomes from CTO revascularization in patients with preserved LVSF (PLVSF) versus reduced LVSF (RLVSF) were assessed.MethodsA total of 2,173 CTO patients were divided into either a PLVSF (n = 1661, Ejection fraction ≥ 50%) or RLVSF (n = 512, 
Source: Clinical Research in Cardiology - September 2, 2020 Category: Cardiology Source Type: research

Long-term s afety of pa clitaxel d r ug-coa t ed balloon-only an gioplasty for de novo coronary artery disease: the SPARTAN DCB study
We present 1517 patients; 429 treated with paclitaxel DCB and 1088 treated with DES. On univariate analysis, age, hypercholesterolaemia, hypertension, peripheral vascular disease, prior myocardial infarction, heart failure, smoking, atrial fibrillation, decreasing estimated glomerular filtration rate (eGFR) [and renal failure (eGFR  
Source: Clinical Research in Cardiology - September 2, 2020 Category: Cardiology Source Type: research

Mid-term hemodynamic and functional results after transcatheter mitral valve leaflet repair with the new PASCAL device
AbstractAimsTo examine the functional and hemodynamic mid-term outcome at 5  months of mitral regurgitation (MR) reduction using the PASCAL repair system.Methods and resultsBetween July 2019 and February 2020 31 consecutive patients with MR 3  +/4 + (mean age 77.5 years, all in New York Heart Association (NYHA) class III–IV, STS score 9.1 ± 7.4) underwent MR reduction in our institute using the PASCAL device. 61.3% had a functional, 29.0% a degenerative, and 9.7% a mixed etiology. Successful implantation was achieved in 30/ 31 (96.8%) patients. 27/31 patients (87.1%...
Source: Clinical Research in Cardiology - August 26, 2020 Category: Cardiology Source Type: research

Risk modeling in transcatheter aortic valve replacement remains unsolved: an external validation study in 2946 German patients
ConclusionsSurgical as well as TAVR-specific risk scoring models showed mediocre performance in prediction of 30-day mortality risk for TAVR in the German Rhine Transregio Aortic Diseases cohort. Development of new or updated risk models is necessary to improve risk stratification.Graphic abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - August 26, 2020 Category: Cardiology Source Type: research

Kidney injury as post-interventional complication of TAVI
AbstractTranscatheter aortic valve implantation (TAVI) is an accepted treatment approach of aortic stenosis. In the beginning, this technique was executed in high-risk patients only. Today, intermediate-risk patients are also amenable for TAVI, as long as the transfemoral approach is chosen. Numerous predictors have been identified that could lead to periprocedural complications and are defined by patient co-morbidities as well as being inherent to the technical approach. Although vascular complications and postinterventional paravalvular regurgitation have been minimized over the past years by revised technologies and tec...
Source: Clinical Research in Cardiology - August 25, 2020 Category: Cardiology Source Type: research

Impact of wearing a facial covering on aerobic exercise capacity in the COVID-19 era: is it more than a feeling?
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - August 24, 2020 Category: Cardiology Source Type: research

Response to the letter to the editor by Kampert et al. entitled “Impact of wearing a facial covering on aerobic exercise capacity in the COVID-19 Era: is it more than a feeling?”
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - August 24, 2020 Category: Cardiology Source Type: research

Interplay of COVID-19 and cardiovascular diseases in Africa: an observational snapshot
AbstractThe COVID-19 pandemic, which started around December 2019 has, at present, resulted in over 450,000 deaths globally, and approximately 1% of these deaths have been reported in Africa. Despite the high prevalence of COVID-19 risk factors, namely: hypertension, diabetes, chronic pulmonary disease, cardiovascular diseases (CVDs) such as rheumatic heart disease, compromised immunity and obesity, low case fatality rates have been recorded in many parts of Africa so far. COVID-19 severity has previously been shown to be worse in patients with CVD and hypertension. We observed the severity of COVID-19 and mortality rates ...
Source: Clinical Research in Cardiology - August 18, 2020 Category: Cardiology Source Type: research

Echocardiographic characteristics of patients with SARS-CoV-2 infection
ConclusionMyocardial involvement due to SARS-CoV-2-infection was highly prevalent in the present cohort —even in patients with mild symptoms. It appears to be characterized by specific speckle tracking deformation abnormalities in the basal LV segments. These data set the stage to prospectively test whether these parameters are helpful for risk stratification and for the long-term follow-up of these patients. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - August 14, 2020 Category: Cardiology Source Type: research

Multi-proteomic approach to predict specific cardiovascular events in patients with diabetes and myocardial infarction: findings from the EXAMINE trial
AbstractBackgroundPatients with diabetes who had a recent myocardial infarction (MI) are at high risk of cardiovascular events. Therefore, risk assessment is important for treatment and shared decisions. We used data from EXAMINE trial to investigate whether a multi-proteomic approach would provide specific proteomic signatures and also improve the prognostic capacity for determining the risk of cardiovascular death, MI, stroke, heart failure [HF], all-cause death, and combinations of these outcomes.Methods93 circulating proteins (92 from the Olink ® CVDII plus troponin) were assessed in 5131 patients. Cox, competing r...
Source: Clinical Research in Cardiology - August 13, 2020 Category: Cardiology Source Type: research

Correction to: Off ‑the‑shelf barrier for emergency intubation in the cardiac catheterization laboratory during the coronavirus disease 2019 (COVID‑19) pandemic
During submission the author name Andreas Link was unfortunately omitted. The correct author list reads as follows. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - August 12, 2020 Category: Cardiology Source Type: research

COVID-19 among heart transplant recipients in Germany: a multicenter survey
AbstractAimsHeart transplantation may represent a particular risk factor for severe coronavirus infectious disease 2019 (COVID-19) due to chronic immunosuppression and frequent comorbidities. We conducted a nation-wide survey of all heart transplant centers in Germany presenting the clinical characteristics of heart transplant recipients with COVID-19 during the first months of the pandemic in Germany.Methods and resultsA multicenter survey of all heart transplant centers in Germany evaluating the current status of COVID-19 among adult heart transplant recipients was performed. A total of 21 heart transplant patients with ...
Source: Clinical Research in Cardiology - August 11, 2020 Category: Cardiology Source Type: research

Association between right-sided cardiac function and ultrasound-based pulmonary congestion on acutely decompensated heart failure: findings from a pooled analysis of four cohort studies
AbstractBackgroundRight ventricular (RV) dysfunction and RV –pulmonary artery (PA) uncoupling are associated with the development of pulmonary congestion during exercise. However, there is limited information regarding the association between these right-sided cardiac parameters and pulmonary congestion in acutely decompensated heart failure (HF).MethodsWe performed an individual patient meta-analysis from four cohort studies of hospitalized patients with HF who had available lung ultrasound (B-lines) data on admission and/or at discharge. RV function was assessed by tricuspid annular plane systolic excursion (TAPSE)...
Source: Clinical Research in Cardiology - August 8, 2020 Category: Cardiology Source Type: research

Correction to: The mystery of “missing” visits in an emergency cardiology department, in the era of COVID-19.; a time-series analysis in a tertiary Greek General Hospital
The original version of this article unfortunately contained a mistake. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - August 7, 2020 Category: Cardiology Source Type: research

Temporal trends in the presentation of cardiovascular and cerebrovascular emergencies during the COVID-19 pandemic in Germany: an analysis of health insurance claims
ConclusionsAdmission rates for cardiovascular and cerebrovascular emergencies declined during the pandemic in Germany, while patients ’ comorbidities and treatment allocations remained unchanged. Further investigation is warranted to identify underlying reasons and potential implications on patients’ outcomes.Graphic abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - August 4, 2020 Category: Cardiology Source Type: research

Decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of COVID-19
ConclusionsThe COVID-19 pandemic was associated with a significant decrease in all-cause admission and admissions due to cardiovascular events in the emergency department. Regarding acute cerebrovascular events there was a numerical decrease but no significant difference. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - August 4, 2020 Category: Cardiology Source Type: research

Genetically determined intelligence and coronary artery disease risk
ConclusionGenetic components of intelligence affect measured intelligence and educational attainment, which subsequently affect the prevalence of CAD via a series of unfavorable risk factor profiles.Graphic abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - August 2, 2020 Category: Cardiology Source Type: research

Assessment of coronary artery disease during hospitalization for cancer treatment
AbstractBackgroundWith improvement of cancer-specific survival, comorbidities and treatment-related side effects, particularly cardiovascular toxicities, need close attention. The aim of the present study was to evaluate clinical characteristics and outcomes of cancer patients requiring coronary angiography during inpatient care.MethodsWe performed a retrospective analysis of patients hospitalized between 02/2011 and 02/2018 in our two university hospital cancer centers. From a cohort of 60,676 cancer patients, we identified 153 patients (65.7  ± 11.6 years, 73.2% male), who underwent coronary ang...
Source: Clinical Research in Cardiology - August 2, 2020 Category: Cardiology Source Type: research

Effect of renal denervation in attenuating the stress of morning surge in blood pressure: post-hoc analysis from the SPYRAL HTN-ON MED trial
ConclusionsThis decrease in the morning DBP surge slope, an index of the sympathetically-mediated morning BP surge, thus indicates a drop in late morning BP relative to early morning/nocturnal BP in the RDN group. Thus, RDN appears effective in attenuating the slope of morning surge in DBP that might indicate possible benefits in a high-risk hypertensive population.Clinical trial registrationhttps://www.clinicaltrials.gov (NCT02439775), registered May 12, 2015. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - August 1, 2020 Category: Cardiology Source Type: research

New technologies for intensive prevention programs after myocardial infarction: rationale and design of the NET-IPP trial
ConclusionsThe randomized multicenter NET-IPP study will evaluate for the first time the effects of a long-term web-based prevention program after MI on clinical events and risk factor control. In a genetic sub study the impact of disclosure of genetic risk using PRS will be investigated. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 30, 2020 Category: Cardiology Source Type: research

Epicardial access for VT ablation: analysis of two different puncture techniques, incidence of adhesions and complication management
ConclusionAnterior-oriented epicardial puncture shows an observed association to a reduced incidence of pericardial tamponades and overall puncture-related complications in epicardial ablation of VA. In cases of repeated epicardial access adhesions increase significantly and may lead to ablation failure. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 27, 2020 Category: Cardiology Source Type: research

Unveiling the mystery of “missing” emergencies in the era of COVID-19 pandemic: a generalized phenomenon with unclarified implications
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 23, 2020 Category: Cardiology Source Type: research

Transcatheter aortic valve replacement from a single vascular access: an ultra-minimalist approach
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 22, 2020 Category: Cardiology Source Type: research

The impact of time-updated resting heart rate on cause-specific mortality in a random middle-aged male population: a lifetime follow-up
AbstractBackgroundA high resting heart rate (RHR) is associated with an increase in adverse events. However, the long-term prognostic value in a general population is unclear. We aimed to investigate the impact of RHR, based on both baseline and time-updated values, on mortality in a middle-aged male cohort.MethodsA random population sample of 852 men, all born in 1913, was followed from age 50 until age 98, with repeated examinations including RHR over a period of 48  years. The impact of baseline and time-updated RHR on cause-specific mortality was assessed using Cox proportional hazard models and cubic spline model...
Source: Clinical Research in Cardiology - July 21, 2020 Category: Cardiology Source Type: research

NAFLD and cardiovascular diseases: a clinical review
AbstractNon-alcoholic fatty liver DISEASE (NAFLD) is the most common chronic liver disease in Western countries and affects approximately 25% of the adult population. Since NAFLD is frequently associated with further metabolic comorbidities such as obesity, type 2 diabetes mellitus, or dyslipidemia, it is generally considered as the hepatic manifestation of the metabolic syndrome. In addition to its potential to cause liver-related morbidity and mortality, NAFLD is also associated with subclinical and clinical cardiovascular disease (CVD). Growing evidence indicates that patients with NAFLD are at substantial risk for the ...
Source: Clinical Research in Cardiology - July 21, 2020 Category: Cardiology Source Type: research

Anti-thrombotic strategies in patients with atrial fibrillation undergoing PCI
AbstractTriple anti-thrombotic therapy combining oral anticoagulation and dual anti-platelet therapy following percutaneous coronary intervention in patients with atrial fibrillation was considered as standard and recommended by guidelines. While bleeding risk is considerable with that approach, data for efficacy are scare. Several trials assessed the possibility of reducing anti-thrombotic treatment by mainly shortening the exposure to acetylsalicylic acid. Dropping one of the anti-platelet components might increase the risk of stent thrombosis, myocardial infarction or stroke. Despite that fear, the recent trials ’...
Source: Clinical Research in Cardiology - July 21, 2020 Category: Cardiology Source Type: research

Impact of COVID-19 outbreak on regional STEMI care in Germany
ConclusionsClinically important indicators for STEMI management were unaffected at the peak of COVID-19, suggesting that the pre-existing logistic structure in the regional STEMI networks preserved high-quality standards even when challenged by a threatening pandemic.Clinical trial registrationNCT00794001 (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 16, 2020 Category: Cardiology Source Type: research

Instant rule-out of suspected non-ST-segment elevation myocardial infarction using high-sensitivity cardiac troponin T with Copeptin versus a single low high-sensitivity cardiac troponin T: findings from a large pooled individual data analysis on 10,329 patients
AbstractBackgroundEvidence is sparse and inconsistent on the role of a dual marker strategy (DMS) combining Copeptin with cardiac troponin T (cTnT) for instant rule-out of a non-ST-segment myocardial infarction (NSTEMI) when high sensitivity cardiac troponin T (hs-cTnT) is used.MethodsData on 10,329 patients from 5 trials were pooled to evaluate initial Copeptin in combination with hs-cTnT against a single marker strategy (SMS) based on hs-cTnT  
Source: Clinical Research in Cardiology - July 15, 2020 Category: Cardiology Source Type: research

Cardiac amyloidosis CT sign
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 13, 2020 Category: Cardiology Source Type: research

Identifying very low-risk STEMI patients for early ICU discharge in the COVID-19 era
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 13, 2020 Category: Cardiology Source Type: research

Collateral damage: Fear from SARS-CoV2-infection causing Takotsubo cardiomyopathy
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 13, 2020 Category: Cardiology Source Type: research

Automatic positive airway pressure for obstructive sleep apnea in heart failure with reduced ejection fraction
ConclusionAPAP intervention was shown to significantly improve outcome compared to control group, represented in percent-predicted peak VO2, an established surrogate marker for cardiovascular prognosis in HFrEF. APAP has additional beneficial effects on hypoxemia, cardiac function and quality of life. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 10, 2020 Category: Cardiology Source Type: research

Collateral damage of COVID-19-lockdown in Germany:  decline of NSTE-ACS admissions
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 10, 2020 Category: Cardiology Source Type: research

Response to paper by Tsioufis et al.
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 10, 2020 Category: Cardiology Source Type: research

Effects of surgical and FFP2/N95 face masks on cardiopulmonary exercise capacity
AbstractBackgroundDue to the SARS-CoV2 pandemic, medical face masks are widely recommended for a large number of individuals and long durations. The effect of wearing a surgical and a FFP2/N95 face mask on cardiopulmonary exercise capacity has not been systematically reported.MethodsThis prospective cross-over study quantitated the effects of wearing no mask (nm), a surgical mask (sm) and a FFP2/N95 mask (ffpm) in 12 healthy males (age 38.1  ± 6.2 years, BMI 24.5 ± 2.0 kg/m2). The 36 tests were performed in randomized order. The cardiopulmonary and metabolic responses wer...
Source: Clinical Research in Cardiology - July 6, 2020 Category: Cardiology Source Type: research

Off-the-shelf barrier for emergency intubation in the cardiac catheterization laboratory during the coronavirus disease 2019 (COVID-19) pandemic
AbstractWith the spread of SARS-CoV-2, it is expected that cases of acute coronary syndrome in the setting of coronavirus disease 2019 (COVID-19) develop. As expensive and sophisticated protection devices are not widely available, we have been working on a simple, off-the-shelf protection device for endotracheal intubation of potentially infected patients. For this purpose, we used a large transparent plastic bag (such as the sterile protective cover of the lead glass shield) for protection from airborne infections. The cover is moved over the patient's head from cranial to caudal, covering the catheter table including the...
Source: Clinical Research in Cardiology - July 4, 2020 Category: Cardiology Source Type: research

The impact of SSRIs on mortality and cardiovascular events in patients with coronary artery disease and depression: systematic review and meta-analysis
ConclusionThe use of SSRIs in post-ACS patients with depression was associated with a 44% relative risk reduction of myocardial infarction. No difference in mortality was found. Given that the quality of the evidence was low, further research is warranted. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - July 2, 2020 Category: Cardiology Source Type: research