Discussion of hemodynamic optimization strategies and the canonical understanding of hemodynamics during biventricular mechanical support in cardiogenic shock: does the flow balance make the difference?
ConclusionsTo monitor and optimize MCS in CS, PA catheterization for hemodynamic measurement is applicable. Higher Impella flow is superior to higher VA-ECMO flow resulting in a more profound increase in CO with subsequent improvement of organ perfusion.Graphical Abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 23, 2024 Category: Cardiology Source Type: research
Renal function and periprocedural complications in patients undergoing left atrial catheter ablation: A comparison between uninterrupted direct oral anticoagulants and phenprocoumon administration
ConclusionThe type of anticoagulation had no significant influence on bleeding or thromboembolic events as well as groin complications in this retrospective study. Despite observing an increased rate of groin complications, the uninterrupted use of DOAC or phenprocoumon during left atrial catheter ablation in patients with CKD appears to be feasible and effective.Graphical AbstractThis figure was created with BioRender.com. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 23, 2024 Category: Cardiology Source Type: research
Patterns of left ventricular remodeling post-myocardial infarction, determinants, and outcome
ConclusionDespite early reperfusion and cardioprotective therapy, adverse LVR remains frequent after acute MI and is associated with a risk of death and HF. A machine learning approach identified and prioritized early variables that are associated with adverse LVR and which were mainly hemodynamic, combining LV volumes, estimates of systolic function, and afterload.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 23, 2024 Category: Cardiology Source Type: research
GLP-1-ra and heart failure-related outcomes in patients with and without history of heart failure: an updated systematic review and meta-analysis
ConclusionGLP1-ra do not decrease HF-hospitalization risk, despite a potential benefit in patients without history of HF, but are effective in reducing ischemic events irrespective of the presence of HF.PROSPERO-registered (CRD42022371264).Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 22, 2024 Category: Cardiology Source Type: research
Echocardiographic predictors of outcome in severe aortic stenosis patients with preserved or reduced ejection fraction
ConclusionsLVEF is not a predictor of short- and long-term mortality after TAVI. In patients with preserved LVEF, left ventricular filling pressure (E/E ´), systolic pulmonary artery pressure (sPAP), and TAPSE are echocardiographic risk factors for increased mortality post TAVI.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 22, 2024 Category: Cardiology Source Type: research
Correction: Acute pulmonary embolism and cancer: findings from the COPE study
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 22, 2024 Category: Cardiology Source Type: research
Echocardiographic predictors of outcome in severe aortic stenosis patients with preserved or reduced ejection fraction
ConclusionsLVEF is not a predictor of short- and long-term mortality after TAVI. In patients with preserved LVEF, left ventricular filling pressure (E/E ´), systolic pulmonary artery pressure (sPAP), and TAPSE are echocardiographic risk factors for increased mortality post TAVI.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 22, 2024 Category: Cardiology Source Type: research
GLP-1-ra and heart failure-related outcomes in patients with and without history of heart failure: an updated systematic review and meta-analysis
ConclusionGLP1-ra do not decrease HF-hospitalization risk, despite a potential benefit in patients without history of HF, but are effective in reducing ischemic events irrespective of the presence of HF.PROSPERO-registered (CRD42022371264).Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 22, 2024 Category: Cardiology Source Type: research
Correction: Acute pulmonary embolism and cancer: findings from the COPE study
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 22, 2024 Category: Cardiology Source Type: research
Determinants and reference values of the 6-min walk distance in the general population —results of the population-based STAAB cohort study
ConclusionIn a representative sample of the general population free from HF, we identified determinants of the 6MWD implying objective physical fitness associated with metabolic health as well as with cardiac structure and function. Furthermore, we derived reference percentiles applicable when using a 15-m hallway.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 18, 2024 Category: Cardiology Source Type: research
Low-flow in aortic valve stenosis patients with reduced ejection fraction does not depend on left ventricular function
ConclusionIn patients with low-flow severe aortic stenosis, low transaortic gradient and cardiac output are not primarily due to LV dysfunction or global changes in gene expression, but may be attributed to other additional cardiac pathologies like mitral regurgitation, atrial fibrillation or right ventricular dysfunction. These factors should also be considered during planning of aortic valve replacement.Graphical AbstractComparison of patients with high-gradient (HG) and low-gradient (LG) aortic stenosis (AS) and reduced ejection fraction. Comprehensive analyses including clinical data, gene expression analyses, cardiova...
Source: Clinical Research in Cardiology - January 18, 2024 Category: Cardiology Source Type: research
Determinants and reference values of the 6-min walk distance in the general population —results of the population-based STAAB cohort study
ConclusionIn a representative sample of the general population free from HF, we identified determinants of the 6MWD implying objective physical fitness associated with metabolic health as well as with cardiac structure and function. Furthermore, we derived reference percentiles applicable when using a 15-m hallway.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 18, 2024 Category: Cardiology Source Type: research
Low-flow in aortic valve stenosis patients with reduced ejection fraction does not depend on left ventricular function
ConclusionIn patients with low-flow severe aortic stenosis, low transaortic gradient and cardiac output are not primarily due to LV dysfunction or global changes in gene expression, but may be attributed to other additional cardiac pathologies like mitral regurgitation, atrial fibrillation or right ventricular dysfunction. These factors should also be considered during planning of aortic valve replacement.Graphical AbstractComparison of patients with high-gradient (HG) and low-gradient (LG) aortic stenosis (AS) and reduced ejection fraction. Comprehensive analyses including clinical data, gene expression analyses, cardiova...
Source: Clinical Research in Cardiology - January 18, 2024 Category: Cardiology Source Type: research
Interaction between anemia and renal dysfunction in relation to long-term survival following acute myocardial infarction
ConclusionAnemia and more advanced CKD are associated with reduced long-term survival post-AMI, inflicting higher risk when conjoined in lower-grade CKD.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 17, 2024 Category: Cardiology Source Type: research
