Unique 40-year survival after heart transplantation with normal graft function and spontaneous operational tolerance
Graphical abstractUnique 40-year survival after heart transplantation with normal graft function and spontaneous operational tolerance. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Long-term outcome of patients presenting with myocardial injury or myocardial infarction
ConclusionPatients with myocardial injury are at a similar increased risk for death and cardiovascular events compared to patients with acute MI. Further studies need to determine appropriate management strategies for patients with myocardial injury.RegistrationClinicaltrials.gov (NCT02355457). (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Association of systemic inflammation with shock severity, 30-day mortality, and therapy response in patients with cardiogenic shock
ConclusionElevated CRP concentrations are associated with increased 30-day in-hospital mortality in unselected patients with cardiogenic shock. The use of mechanical circulatory support attenuates this association.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Coronary microvascular dysfunction in Takotsubo syndrome: an analysis using angiography-derived index of microcirculatory resistance
ConclusionTTS patients had evidence of elevated caIMR in at least one coronary artery with a trend towards higher LAD caIMR in apical type TTS and normalization after recovery. Furthermore, extent of caIMR elevation was associated with increased risk of in-hospital MACE of TTS patients.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Comparing balloon-expandable and self-expanding transfemoral transcatheter aortic valve replacement based on subgroups in Germany 2019/2020
ConclusionIn the direct comparison of balloon-expandable and self-expanding TAVR, there are no differences for in-hospital mortality in subgroups.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Apical hypertrophic cardiomyopathy: pathophysiology, diagnosis and management
AbstractSince the first description of apical hypertrophic cardiomyopathy (ApHCM) in 1976, contrasting information from all over the world has emerged regarding the natural history of the disease. However, the recommended guidelines on hypertrophic cardiomyopathy (HCM) pay a cursory reference to ApHCM, without ApHCM-specific recommendations to guide the diagnosis and management. In addition, cardiologists may not be aware of certain aspects that are specific to this disease subtype, and a robust understanding of specific disease features can facilitate recognition and timely diagnosis. Therefore, the review covers the inci...
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Association between left ventricular ejection fraction, mortality and use of mechanical circulatory support in patients with non-ischaemic cardiogenic shock
ConclusionThis retrospective study may indicate a lower mortality risk with MCS use only in patients with severely reduced LVEF. This may propose the inclusion of LVEF as an adjunctive parameter for MCS decision-making in non-ischaemic CS, aiming to optimise the benefit –risk ratio.Graphical abstractImpact of left ventricular ejection fraction on mortality and use of mechanical circulatory support in non-ischaemic cardiogenic shock. Hazard ratio for 30-day mortality across the LVEF continuum, adjusted for age, sex, SCAI shock stage, worst value of lactate and pH within 6 h, prior resuscitation and mechanical ventilatio...
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Unique 40-year survival after heart transplantation with normal graft function and spontaneous operational tolerance
Graphical abstractUnique 40-year survival after heart transplantation with normal graft function and spontaneous operational tolerance. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Long-term outcome of patients presenting with myocardial injury or myocardial infarction
ConclusionPatients with myocardial injury are at a similar increased risk for death and cardiovascular events compared to patients with acute MI. Further studies need to determine appropriate management strategies for patients with myocardial injury.RegistrationClinicaltrials.gov (NCT02355457). (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Association of systemic inflammation with shock severity, 30-day mortality, and therapy response in patients with cardiogenic shock
ConclusionElevated CRP concentrations are associated with increased 30-day in-hospital mortality in unselected patients with cardiogenic shock. The use of mechanical circulatory support attenuates this association.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Coronary microvascular dysfunction in Takotsubo syndrome: an analysis using angiography-derived index of microcirculatory resistance
ConclusionTTS patients had evidence of elevated caIMR in at least one coronary artery with a trend towards higher LAD caIMR in apical type TTS and normalization after recovery. Furthermore, extent of caIMR elevation was associated with increased risk of in-hospital MACE of TTS patients.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Comparing balloon-expandable and self-expanding transfemoral transcatheter aortic valve replacement based on subgroups in Germany 2019/2020
ConclusionIn the direct comparison of balloon-expandable and self-expanding TAVR, there are no differences for in-hospital mortality in subgroups.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Apical hypertrophic cardiomyopathy: pathophysiology, diagnosis and management
AbstractSince the first description of apical hypertrophic cardiomyopathy (ApHCM) in 1976, contrasting information from all over the world has emerged regarding the natural history of the disease. However, the recommended guidelines on hypertrophic cardiomyopathy (HCM) pay a cursory reference to ApHCM, without ApHCM-specific recommendations to guide the diagnosis and management. In addition, cardiologists may not be aware of certain aspects that are specific to this disease subtype, and a robust understanding of specific disease features can facilitate recognition and timely diagnosis. Therefore, the review covers the inci...
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Association between left ventricular ejection fraction, mortality and use of mechanical circulatory support in patients with non-ischaemic cardiogenic shock
ConclusionThis retrospective study may indicate a lower mortality risk with MCS use only in patients with severely reduced LVEF. This may propose the inclusion of LVEF as an adjunctive parameter for MCS decision-making in non-ischaemic CS, aiming to optimise the benefit –risk ratio.Graphical abstractImpact of left ventricular ejection fraction on mortality and use of mechanical circulatory support in non-ischaemic cardiogenic shock. Hazard ratio for 30-day mortality across the LVEF continuum, adjusted for age, sex, SCAI shock stage, worst value of lactate and pH within 6 h, prior resuscitation and mechanical ventilatio...
Source: Clinical Research in Cardiology - November 20, 2023 Category: Cardiology Source Type: research
Normal age- and sex-based values of right ventricular free wall and four-chamber longitudinal strain by speckle-tracking echocardiography: from the Copenhagen City heart study
ConclusionThis study proposed normal age- and sex-based values of RVFWLS and RV4CLS in a healthy population sample and showed significant sex differences in both measurements across ages.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 15, 2023 Category: Cardiology Source Type: research
