VARC-3 defined outcome of valve-in-valve transcatheter aortic valve implantation in stentless compared with stented aortic bioprostheses
ConclusionSL and ST ViV-TAVI led to comparable short-term outcomes according to VARC-3- defined endpoints and similar mortality rates up to 5 years of follow-up.Graphical abstractVARC-3 defined technical success, device success, and early safety as well as 5-year all-cause mortality in patients undergoing valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) into stentless (SL) compared with stented (ST) failed aortic bioprostheses. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 11, 2023 Category: Cardiology Source Type: research
Metabolically ‘extremely unhealthy’ obese and non-obese patients with diabetes and the risk of cardiovascular events: a French nationwide cohort study
ConclusionBoth non-obese and obese patients with DM with associated cardio-renal-metabolic co-morbidities are an ‘extremely unhealthy’ phenotype with the highest risk of CV death and CV events.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 4, 2023 Category: Cardiology Source Type: research
Detection of atrial fibrillation using an implantable loop recorder in patients with previous cryptogenic stroke: the SPIDER-AF registry (Stroke Prevention by Increasing DEtection Rates of Atrial Fibrillation)
ConclusionsIn the context of cryptogenic strokes ILRs are a valuable tool for early detection of AF. In a real-world scenario, the anticoagulation therapy remains inadequate despite diagnosed AF in a relevant subset of patients requiring optimization of patient management.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 1, 2023 Category: Cardiology Source Type: research
Adherence to oral anticoagulation measured by electronic monitoring in a Belgian atrial fibrillation population
ConclusionOverall adherence to OAC in all study groups, even in SC, was very high, without attrition over time. Nevertheless, targeted education led to a small but significantly improved adherence compared to SC.Graphical Abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 1, 2023 Category: Cardiology Source Type: research
β-blockers may be detrimental in frail patients with heart failure with preserved ejection fraction
ConclusionsUse of β-blockers was significantly associated with worse prognosis specifically in patients with HFpEF and high CFS, but not in those with low CFS. Use of β-blockers in HFpEF patients with frailty may need careful attention.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 29, 2023 Category: Cardiology Source Type: research
Refining accuracy of RV –PA coupling in patients undergoing transcatheter tricuspid valve treatment
ConclusionRV –PA coupling predicts one-year mortality and heart failure rehospitalization after TTVR in patients with TR. The predictability is improved if invasively-measured PA pressure is included.Graphical abstractAssessing right ventricular (RV) function is paramount for risk stratification. The present analysis confirms that RV –PA coupling, measured as TAPSE/PASP, predicts one-year mortality and heart failure rehospitalization in patients undergoing TTVR. There is a significant interaction between TR severity and the correlation of ePASP with iPASP, and therefore the correlation is attenuated in patients with ma...
Source: Clinical Research in Cardiology - November 27, 2023 Category: Cardiology Source Type: research
Liver fibrosis and outcomes of atrial fibrillation: the FIB-4 index
ConclusionsThe FIB-4 index, a non-invasive scoring method for evaluating liver fibrosis, is independently associated with all-cause mortality, MB and HF in patients with AF, suggesting that it may be useful as a risk assessment tool to identify adverse outcomes in patients with AF.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 27, 2023 Category: Cardiology Source Type: research
Refining accuracy of RV –PA coupling in patients undergoing transcatheter tricuspid valve treatment
ConclusionRV –PA coupling predicts one-year mortality and heart failure rehospitalization after TTVR in patients with TR. The predictability is improved if invasively-measured PA pressure is included.Graphical abstractAssessing right ventricular (RV) function is paramount for risk stratification. The present analysis confirms that RV –PA coupling, measured as TAPSE/PASP, predicts one-year mortality and heart failure rehospitalization in patients undergoing TTVR. There is a significant interaction between TR severity and the correlation of ePASP with iPASP, and therefore the correlation is attenuated in patients with ma...
Source: Clinical Research in Cardiology - November 27, 2023 Category: Cardiology Source Type: research
Liver fibrosis and outcomes of atrial fibrillation: the FIB-4 index
ConclusionsThe FIB-4 index, a non-invasive scoring method for evaluating liver fibrosis, is independently associated with all-cause mortality, MB and HF in patients with AF, suggesting that it may be useful as a risk assessment tool to identify adverse outcomes in patients with AF.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 27, 2023 Category: Cardiology Source Type: research
Correction: OECD indicator ‘AMI 30-day mortality’ is neither comparable between countries nor suitable as indicator for quality of acute care
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - November 22, 2023 Category: Cardiology Source Type: research
Angiography-based coronary microvascular assessment with and without intracoronary pressure measurements: a systematic review
ConclusionOur findings suggest that combined angiography- and pressure-based methods provide a more reliable assessment of microvascular resistance compared to methods relying solely on angiography.Graphical AbstractCentral illustration. Comparative assessment of image-based methods quantifying microvascular resistance with and without intracoronary pressure measurements. Angiography-based methods rely on angiography alone to calculate the microvascular resistance by utilizing angiographic frame counting to extrapolate coronary flow (Q) and subsequently deriving distal coronary pressure using fluid dynamic equations. Combi...
Source: Clinical Research in Cardiology - November 21, 2023 Category: Cardiology Source Type: research
