Temperature to time Catch-Up: a novel procedural endpoint to predict durable pulmonary vein isolation after cryoballoon ablation of paroxysmal atrial fibrillation
ConclusionT2T-Catch-Up, a new and simple cryoballoon procedural endpoint demonstrated excellent predictive value and strong statistical association with durable PVI.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research

VT ablation based on CT imaging substrate visualization: results from a large cohort of ischemic and non-ischemic cardiomyopathy patients
ConclusionOur findings indicate that inHEART-guided ablation is associated with reduced VT recurrence compared to conventional procedures. This suggests that employing advanced imaging and computational modeling in VT ablation may be valuable for VT recurrences.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research

Transcatheter left atrial appendage occlusion in patients with chronic kidney disease: a systematic review and meta-analysis
ConclusionsBased on observational studies, LAAO may be an effective option to prevent cardioembolic events in CKD. However, CKD patients may have higher odds of AKI and in-hospital and long-term bleeding and mortality. The adverse clinical outcomes observed in CKD patients may be attributed to this population's high burden of comorbidities, especially among those with ERSD, rather than the LAAO procedure itself. To ensure maximum clinical benefit, careful patient selection, management, and surveillance involving multidisciplinary teams are essential for CKD patients undergoing LAAO.Graphical abstractTranscatheter Left Atri...
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research

Performance of wearable watch-type home blood pressure measurement devices in a real-world clinical sample
ConclusionsWhile we could not formally validate the cuffless devices, our results show that wearable technologies will require improvements to offer reliable BP assessment. This study also highlights the need for validation protocols specifically designed for cuffless BP measurement technologies.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research

Multi-parametric non-contrast cardiac magnetic resonance for the differentiation between cardiac amyloidosis and hypertrophic cardiomyopathy
ConclusionThe T1-to-basal-segmental strain ratio, combining information from segmental circumferential and longitudinal strain and native T1 mapping aids the differentiation between HCM and cardiac amyloidosis with high accuracy and within a fast CMR protocol, obviating the need for contrast agent administration.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 14, 2023 Category: Cardiology Source Type: research

Right ventricular systolic function as a predictor of appropriate ICD therapy
ConclusionA low RVFAC might be associated with increased appropriate ICD therapy.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 13, 2023 Category: Cardiology Source Type: research

Are sarcopenia and its individual components linked to all-cause mortality in heart failure? A systematic review and meta-analysis
ConclusionsCompared to patients with  higher overall functional performance, those with HF and low ALM, low psoas muscle mass, low SPPB, and slow gait speed are at an increased risk of all-cause mortality. Early prevention and/or treatment of lower limb physical function deterioration may be an essential strategy to reduce the ri sk of premature death in HF.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 12, 2023 Category: Cardiology Source Type: research

Chronic kidney disease is related to impaired left ventricular strain as assessed by cardiac magnetic resonance imaging in patients with ischemic cardiomyopathy
ConclusionCKD is related to impaired LV strain as assessed by CMR in patients with ICM. In our cohort, this relationship is independent of LV-EF, the extent of myocardial scarring, diabetes, hypertension, age, gender, LV mass or LV mass index. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 11, 2023 Category: Cardiology Source Type: research

Prognostic utility of a multi-biomarker panel in patients with suspected myocardial infarction
ConclusionNT-proBNP, Apo A-I and KIM-1 emerged as strongest independent predictors of 1-year MACE in patients with suspected MI. Their integration into clinical risk prediction models may improve personalized risk stratification.Graphical abstractPrognostic utility of a multi-biomarker approach in suspected myocardial infarction. In a cohort of 748 patients with symptoms indicative of myocardial infarction (MI) to the emergency department, we measured a 29-biomarker panel and performed regressions, machine learning (ML)-based variable selection and discriminative/reclassification analyses. We identified three biomarkers as...
Source: Clinical Research in Cardiology - December 11, 2023 Category: Cardiology Source Type: research

VARC-3 defined outcome of valve-in-valve transcatheter aortic valve implantation in stentless compared with stented aortic bioprostheses
ConclusionSL and ST ViV-TAVI led to comparable short-term outcomes according to VARC-3- defined endpoints and similar mortality rates up to 5  years of follow-up.Graphical abstractVARC-3 defined technical success, device success, and early safety as well as 5-year all-cause mortality in patients undergoing valve-in-valve transcatheter aortic valve implantation (ViV-TAVI) into stentless (SL) compared with stented (ST) failed aortic bioprostheses. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 11, 2023 Category: Cardiology Source Type: research

Chronic kidney disease is related to impaired left ventricular strain as assessed by cardiac magnetic resonance imaging in patients with ischemic cardiomyopathy
ConclusionCKD is related to impaired LV strain as assessed by CMR in patients with ICM. In our cohort, this relationship is independent of LV-EF, the extent of myocardial scarring, diabetes, hypertension, age, gender, LV mass or LV mass index. (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 11, 2023 Category: Cardiology Source Type: research

Prognostic utility of a multi-biomarker panel in patients with suspected myocardial infarction
ConclusionNT-proBNP, Apo A-I and KIM-1 emerged as strongest independent predictors of 1-year MACE in patients with suspected MI. Their integration into clinical risk prediction models may improve personalized risk stratification.Graphical abstractPrognostic utility of a multi-biomarker approach in suspected myocardial infarction. In a cohort of 748 patients with symptoms indicative of myocardial infarction (MI) to the emergency department, we measured a 29-biomarker panel and performed regressions, machine learning (ML)-based variable selection and discriminative/reclassification analyses. We identified three biomarkers as...
Source: Clinical Research in Cardiology - December 11, 2023 Category: Cardiology Source Type: research