OECD indicator ‘AMI 30-day mortality’ is neither comparable between countries nor suitable as indicator for quality of acute care
ConclusionMost of the variation in AMI hospital mortality is explained by differences in patient registration and organization of care instead of differences in quality of care, which hinders cross-country comparisons of AMI mortality. Europe-wide sentinel regions with comparable registries are necessary to compare (acute) care after myocardial infarction.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - September 8, 2023 Category: Cardiology Source Type: research

Diagnosing post-capillary hypertension in patients with left heart disease: impact of new guidelines
ConclusionApplying the new ESC/ERS 2022 guideline definitions mildly increased the proportion of patients diagnosed with pc-PH (+  5.5%) but markedly increased Cpc-PH diagnoses. This effect was driven by the allocation of patients with formerly unclassifiable forms of post-capillary PH to the Cpc-PH subgroup and a significant shift of patients from the Ipc-PH to the Cpc-PH subgroup.Graphical abstractDistribution of post-capillary pulmonary hypertension (pc-PH) subgroups according to the European Society of Cardiology/European Respiratory Society (ESC/ERS) PH guidelines from 2015 and 2022 in N = 242 patients with left hea...
Source: Clinical Research in Cardiology - September 5, 2023 Category: Cardiology Source Type: research

The treatment of chronic anemia in heart failure: a global approach
AbstractChronic anemia is an independent risk factor for mortality in patients with heart failure (HF). Restoring physiological hemoglobin (Hb) levels is essential to increase oxygen transport capacity to tissues and improve cell metabolism as well as physical and cardiac performance. Nutritional deficits and iron deficiency are the major causes of chronic anemia, but other etiologies include chronic kidney disease, inflammatory processes, and unexplained anemia. Hormonal therapy, including erythropoietin (EPO) and anabolic treatment in chronic anemia HF patients, may contribute to improving Hb levels and clinical outcomes...
Source: Clinical Research in Cardiology - September 3, 2023 Category: Cardiology Source Type: research