Real-time cardiovascular magnetic resonance imaging for non-invasive characterisation of heart failure with preserved ejection fraction: final outcomes of the HFpEF stress trial
ConclusionsLeft atrial function emerged as the strongest predictor for 4-year outcome in the HFpEF Stress Trial. A combination of rest and exercise-stress LA function quantification allows accurate diagnostic and prognostic stratification in HFpEF.Clinicaltrials.gov: NCT03260621.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 3, 2024 Category: Cardiology Source Type: research
Infective endocarditis after isolated aortic valve replacement: comparison between catheter-interventional and surgical valve replacement
ConclusionTAVI patients did not have a significantly higher risk to develop PVE. Our data suggest that TAVI-PVE patients in contrast to SAVR-PVE patients can more often be treated with antibiotics only, presumably due to the lack of a polymeric suture ring.Graphical abstractKey question:What are the differences between SAVR- and TAVI-PVE?Are the current ESC guidelines for the treatment of SAVR-PVE also applicable to TAVI-PVE?Key finding:No significantly different PVE incidences after SAVR and TAVISignificantly better one-year survival and significantly longer survival in TAVI-PVE treated with antibiotics only compared with...
Source: Clinical Research in Cardiology - January 3, 2024 Category: Cardiology Source Type: research
Incidence and progression of atrial fibrillation in patients with and without heart failure using mineralocorticoid receptor antagonists: a meta-analysis
ConclusionMRA use is associated with a reduction in AF risk, especially AF progression. A prominent effect is seen in patients with heart failure, further augmented by therapy duration. Prospective trials are warranted to evaluate MRA use as upstream therapy for preventing this common arrhythmia.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - January 3, 2024 Category: Cardiology Source Type: research
Medical graphics to improve patient understanding and anxiety in elderly and cognitively impaired patients scheduled for transcatheter aortic valve implantation (TAVI)
ConclusionsOur results prove beneficial effects for using medical graphics to inform elderly patients about TAVI by improving patient understanding and reducing periprocedural anxiety (DRKS00021661; 23/Oct/2020).Graphical AbstractMedical graphics entailed significant beneficial effects on the primary endpoints, patient understanding and periprocedural anxiety, compared to the usual patient informed consent (IC) procedure. Patient understanding of IC-related aspects was significantly higher in the Comic group, with a more pronounced benefit in patients with cognitive impairment (p for IC method and cognitive status < ...
Source: Clinical Research in Cardiology - December 20, 2023 Category: Cardiology Source Type: research
Sex differences of sequential changes in coronary blood flow and microvascular function in patients with suspected angina
ConclusionsIn patients with suspected angina but with no obstructed coronary arteries, CMD was especially prevalent among women. Women exhibited higher oxygen consumption, while exhibiting slower and gradual increases in CBF velocities. Conversely, men exhibited faster and steeper increases in CBF velocities even with similar RPP in stress.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research
A multidisciplinary pulmonary embolism response team (PERT): first experience from a single center in Germany
ConclusionPERT implementation was associated with a lower risk of all-cause mortality rate in patients with acute PE. Large prospective studies are needed further to explore the impact of PERTs on clinical outcomes.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research
Comparison of long-term outcome in patients with in-stent restenosis treated with intravascular lithotripsy or with modified balloon angioplasty
ConclusionIVL results in a significantly lower rate of residual stenosis than MB in patients with ISR. During the long-term follow-up, no differences in rates of cardiac death, AMI or TVR were observed.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research
Temperature to time Catch-Up: a novel procedural endpoint to predict durable pulmonary vein isolation after cryoballoon ablation of paroxysmal atrial fibrillation
ConclusionT2T-Catch-Up, a new and simple cryoballoon procedural endpoint demonstrated excellent predictive value and strong statistical association with durable PVI.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research
VT ablation based on CT imaging substrate visualization: results from a large cohort of ischemic and non-ischemic cardiomyopathy patients
ConclusionOur findings indicate that inHEART-guided ablation is associated with reduced VT recurrence compared to conventional procedures. This suggests that employing advanced imaging and computational modeling in VT ablation may be valuable for VT recurrences.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research
Transcatheter left atrial appendage occlusion in patients with chronic kidney disease: a systematic review and meta-analysis
ConclusionsBased on observational studies, LAAO may be an effective option to prevent cardioembolic events in CKD. However, CKD patients may have higher odds of AKI and in-hospital and long-term bleeding and mortality. The adverse clinical outcomes observed in CKD patients may be attributed to this population's high burden of comorbidities, especially among those with ERSD, rather than the LAAO procedure itself. To ensure maximum clinical benefit, careful patient selection, management, and surveillance involving multidisciplinary teams are essential for CKD patients undergoing LAAO.Graphical abstractTranscatheter Left Atri...
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research
Performance of wearable watch-type home blood pressure measurement devices in a real-world clinical sample
ConclusionsWhile we could not formally validate the cuffless devices, our results show that wearable technologies will require improvements to offer reliable BP assessment. This study also highlights the need for validation protocols specifically designed for cuffless BP measurement technologies.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research
Sex differences of sequential changes in coronary blood flow and microvascular function in patients with suspected angina
ConclusionsIn patients with suspected angina but with no obstructed coronary arteries, CMD was especially prevalent among women. Women exhibited higher oxygen consumption, while exhibiting slower and gradual increases in CBF velocities. Conversely, men exhibited faster and steeper increases in CBF velocities even with similar RPP in stress.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research
A multidisciplinary pulmonary embolism response team (PERT): first experience from a single center in Germany
ConclusionPERT implementation was associated with a lower risk of all-cause mortality rate in patients with acute PE. Large prospective studies are needed further to explore the impact of PERTs on clinical outcomes.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research
Comparison of long-term outcome in patients with in-stent restenosis treated with intravascular lithotripsy or with modified balloon angioplasty
ConclusionIVL results in a significantly lower rate of residual stenosis than MB in patients with ISR. During the long-term follow-up, no differences in rates of cardiac death, AMI or TVR were observed.Graphical abstract (Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - December 19, 2023 Category: Cardiology Source Type: research
