Reproducible induction of depressive-like behavior in C57BL/6J mice exposed to chronic social defeat stress with a modified sensory contact protocol
Publication date: Available online 13 July 2021Source: Life SciencesAuthor(s): Yusuke Kamimura, Erina Kuwagaki, Sakika Hamano, Mami Kobayashi, Yukie Yamada, Yuka Takahata, Waka Yoshimoto, Hirotoshi Morimoto, Takeshi Yasukawa, Yoshinobu Uozumi, Kazuki Nagasawa (Source: Life Sciences)
Source: Life Sciences - July 14, 2021 Category: Biology Source Type: research

Evaluation of Edaravone effects on the differentiation of human adipose derived stem cells into oligodendrocyte cells in multiple sclerosis disease in rats
Publication date: Available online 12 July 2021Source: Life SciencesAuthor(s): Mohammad Bakhtiari, Nazem Ghasemi, Hossein Salehi, Noushin Amirpour, Mohammad Kazemi, Mohammad Mardani (Source: Life Sciences)
Source: Life Sciences - July 12, 2021 Category: Biology Source Type: research

Regulation of immune responses through CD39 and CD73 in cancer: Novel checkpoints
Publication date: Available online 12 July 2021Source: Life SciencesAuthor(s): Elham Baghbani, Saeed Noorolyai, Dariush Shanehbandi, Ahad Mokhtarzadeh, Leili Aghebati-Maleki, Vahid Khaze Shahgoli, Oronzo Brunetti, Shima Rahmani, Mahdi Abdoli Shadbad, Amir Baghbanzadeh, Nicola Silvestris, Behzad Baradaran (Source: Life Sciences)
Source: Life Sciences - July 12, 2021 Category: Biology Source Type: research

Functional effects of berberine in modulating mitochondrial dysfunction and inflammatory response in the respective amyloidogenic cells and activated microglial cells – In vitro models simulating Alzheimer's disease pathology
Publication date: Available online 12 July 2021Source: Life SciencesAuthor(s): Ling Rong Wong, Edwin Aik Tan, Ming En Joshua Lim, Wanxiang Shen, Xin Le Lian, Yali Wang, Lu Chen, Paul Chi-Lui Ho (Source: Life Sciences)
Source: Life Sciences - July 12, 2021 Category: Biology Source Type: research

Spontaneous fundus lesions in elderly monkeys: An ideal model for age-related macular degeneration and high myopia clinical research
Publication date: Available online 10 July 2021Source: Life SciencesAuthor(s): Baozhu Zeng, Hening Zhang, Yuting Peng, Huan Yu, Weihua Li, Zhiquan Li, Yaojue Xie, Sujuan Qiu, Peixin Wu, Wang Zhang, Yanwei Liu, Yanming Chen, Xing Liu, Bing Huang (Source: Life Sciences)
Source: Life Sciences - July 12, 2021 Category: Biology Source Type: research

Advance investigation on synthetic small-molecule inhibitors targeting PD-1/PD-L1 signaling pathway
Publication date: Available online 10 July 2021Source: Life SciencesAuthor(s): Annoor Awadasseid, Yanling Wu, Wen Zhang (Source: Life Sciences)
Source: Life Sciences - July 12, 2021 Category: Biology Source Type: research

Safety and efficacy of short-term structured resistance exercise in Gulf War Veterans with chronic unexplained muscle pain: A randomized control trial
Publication date: Available online 10 July 2021Source: Life SciencesAuthor(s): Aaron J. Stegner, Neda E. Almassi, Ryan J. Dougherty, Laura D. Ellingson, Nicholas P. Gretzon, Jacob B. Lindheimer, Jacob V. Ninneman, Stephanie M. Van Riper, Patrick J. O'Connor, Dane B. Cook (Source: Life Sciences)
Source: Life Sciences - July 12, 2021 Category: Biology Source Type: research

A randomized phase II remote study to assess Bacopa for Gulf War Illness associated cognitive dysfunction: Design and methods of a national study
Publication date: Available online 10 July 2021Source: Life SciencesAuthor(s): Amanpreet K. Cheema, Laura E. Wiener, Rebecca B. McNeil, Maria Abreu, Travis Craddock, Mary A. Fletcher, Drew A. Helmer, J. Wesson Ashford, Kimberly Sullivan, Nancy G. Klimas (Source: Life Sciences)
Source: Life Sciences - July 12, 2021 Category: Biology Source Type: research

Mechanism of and strategy to mitigate liraglutide-mediated positive chronotropy
Publication date: Available online 10 July 2021Source: Life SciencesAuthor(s): Christian Jøns, Andreu Porta-Sánchez, Patrick F.H. Lai, Marianne Wauchop, Stéphane Massé, Mohammed Ali Azam, John Asta, Robert A. Rose, Kumaraswamy Nanthakumar (Source: Life Sciences)
Source: Life Sciences - July 12, 2021 Category: Biology Source Type: research

T helper type 1 biased immune responses by PPE17 loaded core-shell alginate-chitosan nanoparticles after subcutaneous and intranasal administration
Publication date: Available online 9 July 2021Source: Life SciencesAuthor(s): Adel Najafi, Kiarash Ghazvini, Mojtaba Sankian, Leila Gholami, Yousef Amini, Sirwan Zare, Farzad Khademi, Mohsen Tafaghodi (Source: Life Sciences)
Source: Life Sciences - July 10, 2021 Category: Biology Source Type: research

Induction of ischemic tolerance by remote perconditioning or postconditioning as neuroprotective strategy for spinal cord motor neurons
Publication date: Available online 10 July 2021Source: Life SciencesAuthor(s): Marianna Danková, Iveta Domoráková, Zuzana Fagová, Milan Stebnický, Eva Mechírová (Source: Life Sciences)
Source: Life Sciences - July 10, 2021 Category: Biology Source Type: research

Protective effects of Nrf2 against sepsis-induced hepatic injury
Publication date: Available online 7 July 2021Source: Life SciencesAuthor(s): Liping Li, Qianwen Zhang, Xi Zhang, Xiaoting Xu, Xinzhi Wang, Xin Huang, Tao Wang, Zhenzhou Jiang, Li Xiao, Luyong Zhang, Lixin Sun (Source: Life Sciences)
Source: Life Sciences - July 8, 2021 Category: Biology Source Type: research

Transfer of miRNA in tumor-derived exosomes suppresses breast tumor cell invasion and migration by inducing M1 polarization in macrophages
Publication date: Available online 7 July 2021Source: Life SciencesAuthor(s): Maryam Moradi-Chaleshtori, Samaneh Shojaei, Samira Mohammadi-Yeganeh, Seyed Mahmoud Hashemi (Source: Life Sciences)
Source: Life Sciences - July 8, 2021 Category: Biology Source Type: research

Corrigendum to “Plantar incision with severe muscle injury can be a cause of long-lasting postsurgical pain in the skin” [Life Sci. 275 (2021) 119389]
Publication date: Available online 7 July 2021Source: Life SciencesAuthor(s): Yuki Yoshiyama, Yuki Sugiyama, Kumiko Ishida, Satoshi Fuseya, Satoshi Tanaka, Mikito Kawamata (Source: Life Sciences)
Source: Life Sciences - July 8, 2021 Category: Biology Source Type: research

An update on Alzheimer's disease: Immunotherapeutic agents, stem cell therapy and gene editing
Publication date: Available online 8 July 2021Source: Life SciencesAuthor(s): Aryaman Girish Patwardhan, Sateesh Belemkar (Source: Life Sciences)
Source: Life Sciences - July 8, 2021 Category: Biology Source Type: research