Recent advances in breast cancer immunotherapy: The promising impact of nanomedicines
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Nastaran Hashemzadeh, Mitra Dolatkhah, Khosro Adibkia, Ayuob Aghanejad, Mohammad Barzegar-Jalali, Yadollah Omidi, Jaleh Barar (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

Inhibition of SGLT1 protects against glycemic variability-induced cardiac damage and pyroptosis of cardiomyocytes in diabetic mice
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Zhenjie Sun, Qian Chai, Ziying Zhang, Dexue Lu, Ziang Meng, Weihua Wu (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

Coating of ferulic acid-loaded silk fibroin nanoparticles with neutrophil membranes: A promising strategy against the acute pancreatitis
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Parichehr Hassanzadeh, Elham Arbabi, Fatemeh Rostami (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

Biomimetic fabrication and application of fibrous-like nanotubes
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Ling Zhang, Yuedan Xu, Xinyang Jin, Chaoyang Wang, Mingxing Li, Zihuai Zhou, Baiping Fu (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

PI3K/AKT activation attenuates acute kidney injury following liver transplantation by inducing FoxO3a nuclear export and deacetylation
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Fanbing Meng, Zheng Zhang, Chaojin Chen, Yue Liu, Dongdong Yuan, Ziqing Hei, Gangjian Luo (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

Extracellular vesicles derived from bone marrow mesenchymal stem cells repair functional and structural rat adrenal gland damage induced by fluoride
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Eman Mohamed Faruk, Wardah Abdullah Alasmari, Hanan Fouad, Ola Elsayed Nafea, Rehab Abd Allah Hasan (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

Protective effect of oral histidine on hypertension in Dahl salt-sensitive rats induced by high-salt diet
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Pengfei Yang, Xinrui Zhao, Luxin Zhou, Yuexin Jin, Xuewei Zheng, Yanan Ouyang, Meng Chen, Li Zeng, Sa Chen, Xiangbo Chen, Zhongmin Tian (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

High salt aggravates renal inflammation via promoting pro-inflammatory macrophage in 5/6-nephrectomized rat
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Yang Liu, Xiaoyan Dai, Shaohua Yang, Yan Peng, Fanfan Hou, Qiugen Zhou (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

Biosensors as a future diagnostic approach for COVID-19
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Suhad Abbas Abid, Ahmed Suhail, Israa M.S. Al-Kadmy, Anas A. Sattar, Amany Magdy Beshbishy, Gaber El-Saber Batiha, Helal F. Hetta (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

Harmine inhibits the proliferation and migration of glioblastoma cells via the FAK/AKT pathway
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Yu-Ge Zhu, Yun-Xia Lv, Chen-Yi Guo, Zhi-Min Xiao, Qun-Guang Jiang, Huang Kuang, Wen-Hua Zhang, Ping Hu (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

Curcumin reduces apoptosis and promotes osteogenesis of human periodontal ligament stem cells under oxidative stress in vitro and in vivo
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Lingping Tan, Zeyuan Cao, Huan Chen, Yunyi Xie, Le Yu, Chuanqiang Fu, Wei Zhao, Yan Wang (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

Sevoflurane improves nerve regeneration and repair of neurological deficit in brain damage rats via microRNA-490-5p/CDK1 axis
Publication date: Available online 26 January 2021Source: Life SciencesAuthor(s): Lingling Ding, Jiaqi Ning, Qi Wang, Bin Lu, Hai Ke (Source: Life Sciences)
Source: Life Sciences - January 27, 2021 Category: Biology Source Type: research

Berberine ameliorates doxorubicin-induced cognitive impairment (chemobrain) in rats
Publication date: 15 March 2021Source: Life Sciences, Volume 269Author(s): Fatma H. Shaker, Marwa O. El-Derany, Sara A. Wahdan, Ebtehal El-Demerdash, Hala O. El-Mesallamy (Source: Life Sciences)
Source: Life Sciences - January 26, 2021 Category: Biology Source Type: research

Treadmill exercise enhances synaptic plasticity in the ischemic penumbra of MCAO mice by inducing the expression of Camk2a via CYFIP1 upregulation
Publication date: Available online 23 January 2021Source: Life SciencesAuthor(s): Weimin Shen, Lingqin Jin, Anqi Zhu, Yao Lin, Guoyuan Pan, Shanshan Zhou, Jingyan Cheng, Jieqiong Zhang, Fengxia Tu, Chan Liu, Qingfeng Xie, Xiang Chen (Source: Life Sciences)
Source: Life Sciences - January 24, 2021 Category: Biology Source Type: research

The protein kinase D1-mediated inflammatory pathway is involved in olanzapine-induced impairment of skeletal muscle insulin signaling in rats
Publication date: Available online 23 January 2021Source: Life SciencesAuthor(s): Chunxia Wang, Chengliang Wang, Liying Ren, Shankang Chen, Wen-Hua Chen, Yuhao Li (Source: Life Sciences)
Source: Life Sciences - January 24, 2021 Category: Biology Source Type: research

Locally activated mitophagy contributes to a “built-in” protection against early burn-wound progression in rats
Publication date: Available online 23 January 2021Source: Life SciencesAuthor(s): Songxue Guo, Quan Fang, Leilei Chen, Meirong Yu, Yike Chen, Nan Li, Chunmao Han, Xueqing Hu (Source: Life Sciences)
Source: Life Sciences - January 24, 2021 Category: Biology Source Type: research

Trilobatin ameliorates bone loss via suppression of osteoclast cell differentiation and bone resorptive function in vitro and in vivo
Publication date: Available online 23 January 2021Source: Life SciencesAuthor(s): Seong Cheol Kim, Hyeon Jeong Kim, Gi Eun Park, Ramesh Prasad Pandey, Jisun Lee, Jae Kyung Sohng, Yong Il Park (Source: Life Sciences)
Source: Life Sciences - January 24, 2021 Category: Biology Source Type: research

Aerobic exercise attenuates ectopic renal sinus adipose tissue accumulation-related renal hypoxia injury in obese mice
Publication date: Available online 23 January 2021Source: Life SciencesAuthor(s): Sha-sha Wang, Qing Gu, Nian Liu, Jingyuan Li, Xiangyun Liu (Source: Life Sciences)
Source: Life Sciences - January 24, 2021 Category: Biology Source Type: research

Network pharmacology and molecular docking reveal the mechanism of Scopoletin against non-small cell lung cancer
Publication date: Available online 23 January 2021Source: Life SciencesAuthor(s): Chong Yuan, Meng-Heng Wang, Fei Wang, Peng-Yu Chen, Xin-Ge Ke, Bing Yu, Yan-Fang Yang, Peng-Tao You, He-Zhen Wu (Source: Life Sciences)
Source: Life Sciences - January 24, 2021 Category: Biology Source Type: research

MicroRNA-376b-5p targets SOX7 to alleviate ischemic brain injury in a mouse model through activating Wnt/β-catenin signaling pathway
Publication date: Available online 19 January 2021Source: Life SciencesAuthor(s): Bin Zhao, Peng Wang, Jing Yu, Yizhi Zhang (Source: Life Sciences)
Source: Life Sciences - January 20, 2021 Category: Biology Source Type: research

Membrane dynamics simulation and virtual screening reveals potential dual natural inhibitors of endothelin receptors for targeting glaucomatous condition
Publication date: Available online 19 January 2021Source: Life SciencesAuthor(s): Hemavathy Nagarajan, Umashankar Vetrivel (Source: Life Sciences)
Source: Life Sciences - January 20, 2021 Category: Biology Source Type: research

Knocking down of Polo-like kinase 2 inhibits cell proliferation and induced cell apoptosis in human glioma cells
Publication date: Available online 19 January 2021Source: Life SciencesAuthor(s): Fang Cao, Xiangping Xia, Yinchun Fan, Qian Liu, Jiancheng Song, Qiang Zhang, Yu Guo, Shengtao Yao (Source: Life Sciences)
Source: Life Sciences - January 20, 2021 Category: Biology Source Type: research

Beinaglutide shows significantly beneficial effects in diabetes/obesity-induced nonalcoholic steatohepatitis in ob/ob mouse model
Publication date: Available online 19 January 2021Source: Life SciencesAuthor(s): Xiankang Fang, Zhiqiang Du, Chunling Duan, Shanshan Zhan, Tian Wang, Mengyu Zhu, Jiajie Shi, Juan Meng, Xianhua Zhang, Maiyun Yang, Yajun Zuo (Source: Life Sciences)
Source: Life Sciences - January 20, 2021 Category: Biology Source Type: research

The MIR155 host gene/microRNA-627/HMGB1/NF-κB loop modulates fibroblast proliferation and extracellular matrix deposition
Publication date: Available online 20 January 2021Source: Life SciencesAuthor(s): Jie Li, Xueyu Zhang, Tao Wang, Jinghong Li, Qi Su, Cheng Zhong, Zhongshu Chen, Ying Liang (Source: Life Sciences)
Source: Life Sciences - January 20, 2021 Category: Biology Source Type: research

Vaspin regulated cartilage cholesterol metabolism through miR155/LXRα and participated in the occurrence of osteoarthritis in rats
Publication date: Available online 20 January 2021Source: Life SciencesAuthor(s): Hangyuan He, Mengting Lu, Huasong Shi, Guoping Yue, Hanwen Luo (Source: Life Sciences)
Source: Life Sciences - January 20, 2021 Category: Biology Source Type: research

The role of myeloid-derived suppressor cells in rheumatoid arthritis: An update
Publication date: Available online 20 January 2021Source: Life SciencesAuthor(s): Jamshid Gholizadeh Navashenaq, Arezoo Gowhari Shabgah, Mahdiyeh Hedayati-Moghadam, Nazila Ariaee, Hamed Mohammadi, Maryam Hemmatzadeh, Sara Azhdari, Tannaz Jamialahmadi, Thozhukat Sathyapalan, Amirhossein Sahebkar (Source: Life Sciences)
Source: Life Sciences - January 20, 2021 Category: Biology Source Type: research

The inhibitive effects of proteasome inhibitor MG-132 on pterygium fibroblasts in vitro and the potential key regulators involved
Publication date: Available online 20 January 2021Source: Life SciencesAuthor(s): Dandan Zhao, Hongxia Zhao, Yang He, Yang Yang, Yan Du, Meixia Zhang (Source: Life Sciences)
Source: Life Sciences - January 20, 2021 Category: Biology Source Type: research

Statistical analysis of COVID-19 infection caused by environmental factors: Evidence from Pakistan
Publication date: Available online 18 January 2021Source: Life SciencesAuthor(s): Muhammad Fawad, Sumaira Mubarik, Saima Shakil Malik, Jingli Ren (Source: Life Sciences)
Source: Life Sciences - January 19, 2021 Category: Biology Source Type: research

Overexpression of FUBP1 is associated with human cervical carcinoma development and prognosis
Publication date: Available online 18 January 2021Source: Life SciencesAuthor(s): Caiqi Ma, Zhijian Huang, Zhikun Wu, Chunguang Di, Xuepin Lin, Mao Huang, Honghai Hong, Haofan Yin (Source: Life Sciences)
Source: Life Sciences - January 19, 2021 Category: Biology Source Type: research

CDK5 inhibition protects against OGDR induced mitochondrial fragmentation and apoptosis through regulation of Drp1S616 phosphorylation
Publication date: Available online 18 January 2021Source: Life SciencesAuthor(s): Chunli Chen, Xiaoxia Peng, Jiayu Tang, Zhiping Hu, Jieqiong Tan, Liuwang Zeng (Source: Life Sciences)
Source: Life Sciences - January 19, 2021 Category: Biology Source Type: research

Estrogens as regulator of hematopoietic stem cell, immune cells and bone biology
Publication date: Available online 18 January 2021Source: Life SciencesAuthor(s): Rupali Sani Kumar, Neena Goyal (Source: Life Sciences)
Source: Life Sciences - January 19, 2021 Category: Biology Source Type: research

Recent trends in cancer therapy: A review on the current state of gene delivery
Publication date: Available online 19 January 2021Source: Life SciencesAuthor(s): Esam Bashir Yahya, Amaal Mohammed Alqadhi (Source: Life Sciences)
Source: Life Sciences - January 19, 2021 Category: Biology Source Type: research

Heat precondition is a potential strategy to combat hepatic injury triggered by severe heat stress
Publication date: Available online 19 January 2021Source: Life SciencesAuthor(s): Avinash Gupta, Dolly Sharma, Harshita Gupta, Ajeet Singh, Daipayan Chowdhury, Ramesh Chand Meena, Lilly Ganju, Bhuvnesh Kumar (Source: Life Sciences)
Source: Life Sciences - January 19, 2021 Category: Biology Source Type: research

Exercise and food supplement of vitamin C ameliorate hypertension through improvement of gut microflora in the spontaneously hypertensive rats
Publication date: Available online 19 January 2021Source: Life SciencesAuthor(s): Ying Li, Salman Zafar, Rawya Mohamed Salih Ibrahim, Hong-Li Chi, Tong Xiao, Wen-jie Xia, Hong-Bao Li, Yu-Ming Kang (Source: Life Sciences)
Source: Life Sciences - January 19, 2021 Category: Biology Source Type: research

DJ-1 modulates Nrf2-mediated MRP1 expression by activating Wnt3a/β-catenin signalling in A549 cells exposed to cigarette smoke extract and LPS
Publication date: Available online 19 January 2021Source: Life SciencesAuthor(s): Jian Zhou, Chuanzong Qi, Xin Fang, Zihao Wang, Shuyi Zhang, Dalang Li, Jue Song (Source: Life Sciences)
Source: Life Sciences - January 19, 2021 Category: Biology Source Type: research

Protective effect of Rosuvastatin on Azithromycin induced cardiotoxicity in a rat model
Publication date: Available online 19 January 2021Source: Life SciencesAuthor(s): Basma S. Mansour, Noha A. Salem, Ghada Abdel Kader, Gamal Abdel-Alrahman, Omayma M. Mahmoud (Source: Life Sciences)
Source: Life Sciences - January 19, 2021 Category: Biology Source Type: research

Combining 18F-FDG PET and Gd-EOB-DTPA-enhanced MRI for staging liver fibrosis
Publication date: Available online 18 January 2021Source: Life SciencesAuthor(s): Shen Pan, Lu Wang, Jun Xin (Source: Life Sciences)
Source: Life Sciences - January 18, 2021 Category: Biology Source Type: research

Astragaloside IV protects against podocyte apoptosis by inhibiting oxidative stress via activating PPARγ-Klotho-FoxO1 axis in diabetic nephropathy
Publication date: Available online 18 January 2021Source: Life SciencesAuthor(s): Lina Xing, Ji Fang, Bingbing Zhu, Li Wang, Junliang Chen, Yunman Wang, Jiebo Huang, Hao Wang, Xingmei Yao (Source: Life Sciences)
Source: Life Sciences - January 18, 2021 Category: Biology Source Type: research

Luteolin alleviates inflammation and modulates gut microbiota in ulcerative colitis rats
Publication date: 15 March 2021Source: Life Sciences, Volume 269Author(s): Bolin Li, Pengli Du, Yao Du, Danyang Zhao, Yanru Cai, Qian Yang, Zijing Guo (Source: Life Sciences)
Source: Life Sciences - January 18, 2021 Category: Biology Source Type: research

Defining the functionally sufficient regulatory region and liver-specific roles of the erythropoietin gene by transgene complementation
Publication date: Available online 16 January 2021Source: Life SciencesAuthor(s): Shun Yamazaki, Ikuo Hirano, Koichiro Kato, Masayuki Yamamoto, Norio Suzuki (Source: Life Sciences)
Source: Life Sciences - January 17, 2021 Category: Biology Source Type: research

Down-regulation of MALAT1 aggravates polycystic ovary syndrome by regulating MiR-302d-3p-mediated leukemia inhibitory factor activity
Publication date: Available online 16 January 2021Source: Life SciencesAuthor(s): Yafei Chen, Yajie Chen, Xiaoli Cui, Qiujuan He, Hongjuan Li (Source: Life Sciences)
Source: Life Sciences - January 17, 2021 Category: Biology Source Type: research

Cigarette smoke extract induces pyroptosis in human bronchial epithelial cells through the ROS/NLRP3/caspase-1 pathway
Publication date: Available online 16 January 2021Source: Life SciencesAuthor(s): Meng-Yu Zhang, Ying-Xiao Jiang, Yi-Can Yang, Jian-Yu Liu, Chen Huo, Xiu-Li Ji, Yi-Qing Qu (Source: Life Sciences)
Source: Life Sciences - January 17, 2021 Category: Biology Source Type: research

A novel carcinogenic PI3Kα mutation suggesting the role of helical domain in transmitting nSH2 regulatory signals to kinase domain
Publication date: 15 March 2021Source: Life Sciences, Volume 269Author(s): Safoura Ghalamkari, Shahryar Alavi, Hamidreza Mianesaz, Farinaz Khosravian, Amir Bahreini, Mansoor Salehi (Source: Life Sciences)
Source: Life Sciences - January 17, 2021 Category: Biology Source Type: research

Biological processes and key druggable targets involved in age-associated memory loss: A systematic review
Publication date: Available online 15 January 2021Source: Life SciencesAuthor(s): P. Ambili Unni, Girinath G. Pillai, S. Sajithalulu (Source: Life Sciences)
Source: Life Sciences - January 17, 2021 Category: Biology Source Type: research

Thrombin inhibitor argatroban modulates bone marrow stromal cells behaviors and promotes osteogenesis through canonical Wnt signaling
Publication date: Available online 15 January 2021Source: Life SciencesAuthor(s): Jian Song, Nan Jiang, Xueqi Gan, Wei Zhi, Zhuoli Zhu (Source: Life Sciences)
Source: Life Sciences - January 17, 2021 Category: Biology Source Type: research

RIPK1 contributes to cisplatin-induced apoptosis of esophageal squamous cell carcinoma cells via activation of JNK pathway
Publication date: Available online 15 January 2021Source: Life SciencesAuthor(s): Yuliu Zhang, Jianping Du, Xiaofan Duan, Wei Peng, Lei Lv, Zhiyu Chen, Yumei Zhang (Source: Life Sciences)
Source: Life Sciences - January 17, 2021 Category: Biology Source Type: research

Berberine ameliorates doxorubicin-induced cognitive impairment (chemo brain) in rats
Publication date: Available online 15 January 2021Source: Life SciencesAuthor(s): Fatma H. Shaker, Marwa O. El-Derany, Sara A. Wahdan, Ebtehal El-Demerdash, Hala O. El-Mesallamy (Source: Life Sciences)
Source: Life Sciences - January 17, 2021 Category: Biology Source Type: research

A comparative study of acarbose, vildagliptin and saxagliptin intended for better efficacy and safety on type 2 diabetes mellitus treatment
Publication date: Available online 15 January 2021Source: Life SciencesAuthor(s): Zhongchao Wang, Jing Wang, Jianxia Hu, Ying Chen, Bingzi Dong, Yangang Wang (Source: Life Sciences)
Source: Life Sciences - January 17, 2021 Category: Biology Source Type: research

Gonadotropin-inhibiting hormone promotes apoptosis of bovine ovary granulosa cells
Publication date: Available online 15 January 2021Source: Life SciencesAuthor(s): Xu Li, Gaoqing Xu, Zhiqiang Li, Hongyu Liu, Xin Ma, Lianyu Yang, Pengju Zhang, Jing Zhao, Jun Wang, Wenfa Lu (Source: Life Sciences)
Source: Life Sciences - January 17, 2021 Category: Biology Source Type: research

Effect of caloric restriction on alveolar bone loss in rats
Publication date: Available online 16 January 2021Source: Life SciencesAuthor(s): Evelyn Lopez Soares, Fábio André dos Santos, Tayline Mroczek, Debora Cristina de Lima, Hemily Victória Bardini Josefino, Luise Adrieli Bochenek da Silva, Leomar Emanuel Almeida Mecca, Gilson Cesar Nobre Franco (Source: Life Sciences)
Source: Life Sciences - January 17, 2021 Category: Biology Source Type: research