Filtered By:
Nutrition: Calcium

This page shows you your search results in order of relevance. This is page number 10.

Order by Relevance | Date

Total 1776 results found since Jan 2013.

Myogenic Tone as a Therapeutic Target for Ischemic Stroke.
Abstract Ischemic stroke causes vascular paralysis and impaired autoregulation in the brain, the degree of which is dependent on the depth and duration of ischemia and reperfusion (I/R). Ischemic stroke also impairs myogenic response of middle cerebral arteries (MCA) that may be an underlying mechanism by which autoregulation is impaired. Myogenic responses are affected by I/R through several mechanisms, including production of peroxynitrite, depolymerization of F-actin in vascular smooth muscle, and circulating vasoactive factors. The vascular endothelium is also significantly affected during focal ischemia that ...
Source: Current Vascular Pharmacology - September 25, 2013 Category: Drugs & Pharmacology Authors: Palomares SM, Cipolla MJ Tags: Curr Vasc Pharmacol Source Type: research

Blocking a vicious cycle nNOS/peroxynitrite/AMPK by S-nitrosoglutathione: implication for stroke therapy
Conclusions: Taken together, these results indicate an injurious nNOS/peroxynitrite/AMPK cycle following stroke, and GSNO treatment of IR inhibits this vicious cycle, resulting in neuroprotection and improved neurological function. GSNO is a natural component of the human body, and its exogenous administration to humans is not associated with any known side effects. Currently, the FDA-approved thrombolytic therapy suffers from a lack of neuronal protective activity. Because GSNO provides neuroprotection by ameliorating stroke’s initial and causative injuries, it is a candidate of translational value for stroke therapy.
Source: BMC Neuroscience - July 15, 2015 Category: Neuroscience Authors: Mushfiquddin KhanTajinder DhammuFumiyo MatsudaAvtar SinghInderjit Singh Source Type: research

Pertussis toxin reduces calcium influx to protect ischemic stroke in a middle cerebral artery occlusion model
This article is protected by copyright. All rights reserved.
Source: Journal of Neurochemistry - September 1, 2015 Category: Neuroscience Authors: Zhiwei Tang, Shiping Li, Pengcheng Han, Junxiang Yin, Yan Gan, Qingwei Liu, Jinkun Wang, Chongqian Wang, Yu Li, Jiong Shi Tags: Original Article Source Type: research

Disruption of IP3R2-mediated Ca(2+) signaling pathway in astrocytes ameliorates neuronal death and brain damage while reducing behavioral deficits after focal ischemic stroke.
Abstract Inositol trisphosphate receptor (IP3R)-mediated intracellular Ca(2+) increase is the major Ca(2+) signaling pathway in astrocytes in the central nervous system (CNS). Ca(2+) increases in astrocytes have been found to modulate neuronal function through gliotransmitter release. We previously demonstrated that astrocytes exhibit enhanced Ca(2+) signaling in vivo after photothrombosis (PT)-induced ischemia, which is largely due to the activation of G-protein coupled receptors (GPCRs). The aim of this study is to investigate the role of astrocytic IP3R-mediated Ca(2+) signaling in neuronal death, brain damage ...
Source: Cell Calcium - September 25, 2015 Category: Cytology Authors: Li H, Xie Y, Zhang N, Yu Y, Zhang Q, Ding S Tags: Cell Calcium Source Type: research

Visit-to-visit blood pressure variability and classes of antihypertensive agents; associations with artery remodeling and the risk of stroke.
Abstract Recent studies have shown that visit-to-visit blood pressure (BP) variability was emerging as an independent risk factor for stroke. Although the mechanism is not fully understood, artery remodeling would be closely associated with the relationship between visit-to-visit BP variability and stroke. In addition, the class of antihypertensive agents is suggested to be an important determinant of visit-to-visit BP variability. This review article summarizes the recent literature on these topics. In the elderly hypertensives, strict BP control using calcium channel blockade would play a crucial role to prevent...
Source: Current Pharmaceutical Design - November 12, 2015 Category: Drugs & Pharmacology Authors: Nagai M, Dote K, Kato M, Sasaki S, Oda N, Kagawa E, Nakano Y, Yamane A, Kubo Y, Higashihara T, Miyauchi S, Harada W Tags: Curr Pharm Des Source Type: research

The effect of swimming and type of stroke on bone metabolism in competitive adolescent swimmers: a pilot study.
CONCLUSION: This was the first study to evaluate the effect of swimming stroke on BMD. Although no effect was statistically shown, further studies with a larger series may determine this effect. PMID: 26422853 [PubMed - indexed for MEDLINE]
Source: Turkish Journal of Medical Sciences - December 2, 2015 Category: Journals (General) Tags: Turk J Med Sci Source Type: research

Dietary choline and betaine; associations with subclinical markers of cardiovascular disease risk and incidence of CVD, coronary heart disease and stroke: the Jackson Heart Study
ConclusionsAmong our African-American participants, higher dietary choline intake was associated with a lower risk of incident ischemic stroke, and thus putative dietary benefits. Higher dietary betaine intake was associated with a nonlinear higher risk of incident CHD.
Source: European Journal of Nutrition - August 21, 2016 Category: Nutrition Source Type: research

Effects of Shuxuetong injection applied in acute ischemic stroke
Conclusions Adjuvant treatment with Shuxuetong injection can reduce the injury of nerve function of patients with ischemic stroke and improve blood lipid metabolism and blood coagulation function, which is an effective drug for the treatment of ischemic stroke.
Source: Journal of Acute Disease - September 20, 2016 Category: Emergency Medicine Source Type: research

How To Lower Risk of Heart Disease and Stroke
Italy's Emma Morano will be celebrating her 117th birthday at the end of this month. She's the oldest living person in the world. And when she was asked what her secret to longevity was, she didn't miss a beat. Her answer? She eats two or three eggs every day.  I'm not at all surprised by Emma's long, healthy life. People thrived on eggs for millions of years. The Myth of Eggs and Cholesterol That is, until the 1950s, when they came under attack because they're high in cholesterol. Around that time, cholesterol was blamed for causing heart disease. And we now know that's not true. Choleste...
Source: Al Sears, MD Natural Remedies - December 15, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Source Type: news

Astrocytic calcium release mediates peri-infarct depolarizations in a rodent stroke model
Stroke is one of the most common diseases and a leading cause of death and disability. Cessation of cerebral blood flow (CBF) leads to cell death in the infarct core, but tissue surrounding the core has the potential to recover if local reductions in CBF are restored. In these areas, detrimental peri-infarct depolarizations (PIDs) contribute to secondary infarct growth and negatively affect stroke outcome. However, the cellular pathways underlying PIDs have remained unclear. Here, we have used in vivo multiphoton microscopy, laser speckle imaging of CBF, and electrophysiological recordings in a mouse model of focal ischemi...
Source: Journal of Clinical Investigation - December 20, 2016 Category: Biomedical Science Authors: Cordula Rakers, Gabor C. Petzold Source Type: research

How To Lower Risk of Heart Disease and Stroke
Italy's Emma Morano will be celebrating her 117th birthday at the end of this month. She's the oldest living person in the world. And when she was asked what her secret to longevity was, she didn't miss a beat. Her answer? She eats two or three eggs every day.  I'm not at all surprised by Emma's long, healthy life. People thrived on eggs for millions of years. The Myth of Eggs and Cholesterol That is, until the 1950s, when they came under attack because they're high in cholesterol. Around that time, cholesterol was blamed for causing heart disease. And we now know that's not true. Choleste...
Source: Al Sears, MD Natural Remedies - December 15, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Source Type: news

Relationship Between Nutritional Factors and Hip Bone Density in Individuals with Chronic Stroke
AbstractThe aim of this study was to investigate the relationship between dietary habits and hip bone health in community-dwelling individuals with chronic stroke. The usual dietary intake of 94 individuals with chronic stroke (30 women, mean age: 59.0  years) was assessed by a 3-day food record within a single week. Dual-energy X-ray absorptiometry was used to measure bone mineral density (BMD) at both hips. The results showed that low hip bone mass was found in 59 and 50 of the participants on the affected and unaffected side, respectively. The mean hip BMD was also significantly lower on the affected side than the unaf...
Source: Calcified Tissue International - April 17, 2017 Category: Orthopaedics Source Type: research

Review finds no link between dairy and heart attack or stroke risk
Conclusion This large meta-analysis of cohort studies demonstrated no increased risk to cardiovascular disease, coronary heart disease or all-cause death from eating dairy products. The review has strengths in its large size and the fact it was able to analyse different types of dairy product, such as high and low-fat and everyday products such as cheese and yoghurt. However, there are a number of factors to consider: The results of a systematic review are only as good as the quality of the underlying studies. These are all observational studies and it's possible that unadjusted health and lifestyle factors are having an...
Source: NHS News Feed - May 9, 2017 Category: Consumer Health News Tags: Food/diet Heart/lungs Neurology Source Type: news

TRPV4 channels contribute to calcium transients in astrocytes and neurons during peri ‐infarct depolarizations in a stroke model
In this study, we investigated the role of two astroglial membrane channels, transient receptor vanilloid 4 (TRPV4) channel and aquaporin‐4 (AQP4). We combined in vivo multiphoton microscopy, electrophysiology as well as laser speckle contrast imaging with the middle cerebral artery occlusion stroke model. Using knockout mice and pharmacological inhibitors, we found that TRPV4 channels contribute to calcium influx into astrocytes and neurons and subsequent extracellular glutamate accumulation during PIDs. AQP4 neither influenced PID‐related calcium signals nor PID‐related edema of astrocyte somata. Both channels did ...
Source: Glia - June 22, 2017 Category: Neurology Authors: Cordula Rakers, Matthias Schmid, Gabor C. Petzold Tags: RESEARCH ARTICLE Source Type: research

Effects of Cilnidipine, an L/N-Type Calcium Channel Blocker, on Carotid Atherosclerosis in Japanese Post-Stroke Hypertensive Patients: Results from the CA-ATTEND Study.
CONCLUSIONS: Cilnidipine promoted the regression of common carotid IMT in post-stroke hypertensive patients, especially in the thick group. Cilnidipine also reduced the IAD in both normal and thick groups. PMID: 29225324 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - December 12, 2017 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research