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Total 1776 results found since Jan 2013.

Fibroblast Growth Factor 23 and Risk of Incident Stroke in Community-Living Adults Clinical Sciences
Conclusions— Higher FGF23 concentrations were associated with higher risk of cardioembolic but not with other stroke subtypes in community-dwelling adults. Additional studies should delineate reasons for these findings.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Panwar, B., Jenny, N. S., Howard, V. J., Wadley, V. G., Muntner, P., Kissela, B. M., Judd, S. E., Gutierrez, O. M. Tags: Acute Cerebral Infarction, Embolic stroke, Epidemiology Clinical Sciences Source Type: research

Revised Framingham Stroke Risk Score, Nontraditional Risk Markers, and Incident Stroke in a Multiethnic Cohort Clinical Sciences
Conclusions—The R-FSRS downgraded stroke risk but had better calibration and discriminative ability for incident stroke compared with the original FSRS. Nontraditional risk markers modestly improved the discriminative ability of the R-FSRS, with coronary artery calcium performing the best.
Source: Stroke - January 22, 2018 Category: Neurology Authors: Peter Flueckiger, Will Longstreth, David Herrington, Joseph Yeboah Tags: Epidemiology, Primary Prevention, Race and Ethnicity, Risk Factors, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Neuroimaging, serum biomarkers, and patient characteristics as predictors of upper limb functioning 12 weeks after acute stroke: an observational, prospective study.
CONCLUSION: ASPECTS score ≥ 8 within 24 hours and S100β protein < 140.5 ng/L at 48 hours predict better upper limb functioning, while advanced age predicts worse upper limb functioning 12 weeks after stroke. PMID: 30213243 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - September 13, 2018 Category: Neurology Authors: Branco JP, Oliveira S, Sargento-Freitas J, Galego O, Cordeiro G, Cunha L, Freire Gonçalves A, Pinheiro J Tags: Top Stroke Rehabil Source Type: research

Intracranial Carotid Calcification on Cranial Computed Tomography: Visual Scoring Methods, Semiautomated Scores, and Volume Measurements in Patients With Stroke Clinical Sciences
Conclusions— Visual scores correlate highly with quantitative intracranial internal carotid artery calcification measures, with excellent observer agreements. Visual intracranial internal carotid artery scores could be a rapid and practical method for epidemiological studies.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Subedi, D., Zishan, U. S., Chappell, F., Gregoriades, M.-L., Sudlow, C., Sellar, R., Wardlaw, J. Tags: Cerebrovascular disease/stroke, CT and MRI, Carotid Stenosis, Risk Factors for Stroke Clinical Sciences Source Type: research

Response of Day-to-Day Home Blood Pressure Variability by Antihypertensive Drug Class After Transient Ischemic Attack or Nondisabling Stroke Clinical Sciences
Conclusions— After transient ischemic attack or minor stroke, calcium channel blockers and diuretics reduced variability and maximum home SBP, primarily because of effects on morning readings. Home BP readings enable monitoring of response to SBP variability-directed treatment in patients with recent cerebrovascular events.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Webb, A. J. S., Wilson, M., Lovett, N., Paul, N., Fischer, U., Rothwell, P. M. Tags: Secondary prevention, Cerebrovascular disease/stroke Clinical Sciences Source Type: research

Early Blood-Brain Barrier Disruption in Ischemic Stroke Initiates Multifocally Around Capillaries/Venules Basic Sciences
Conclusions—Early BBBD in focal cerebral ischemia initiates multifocally in the distal capillary and venular bed of the cerebral microvasculature. It is closely associated with perimicrovascular vasogenic edema and microglial activation and predicts the extent of final infarction.
Source: Stroke - May 25, 2018 Category: Neurology Authors: Angelika Hoffmann, Tassilo Dege, Reiner Kunze, Anne–Sophie Ernst, Holger Lorenz, Laura–Ines Bohler, Thomas Korff, Hugo H. Marti, Sabine Heiland, Martin Bendszus, Xavier Helluy, Mirko Pham Tags: Biomarkers, Vascular Biology, Magnetic Resonance Imaging (MRI), Blood-Brain Barrier, Ischemic Stroke Original Contributions Source Type: research

Intakes of magnesium, potassium, and calcium and the risk of stroke among men
ConclusionsA diet rich in magnesium, potassium, and calcium may contribute to reduced risk of stroke among men. Because of significant collinearity, the independent contribution of each cation is difficult to define.
Source: International Journal of Stroke - June 4, 2015 Category: Neurology Authors: Sally N. Adebamowo, Donna Spiegelman, Alan J. Flint, Walter C. Willett, Kathryn M. Rexrode Tags: Research Source Type: research

Comparative effects of antihypertensive drugs on stroke outcome in China
ConclusionThis study suggests that early initiation of calcium channel blockers is associated with improved outcome after stroke. Further randomized studies are warranted to confirm these findings and to delineate differential beneficial effects of antihypertensive therapy in stroke prevention.
Source: International Journal of Stroke - July 1, 2014 Category: Neurology Authors: Emma L. Heeley, Jade W. Wei, Ji‐Guang Wang, Hisatomi Arima, Yining Huang, Lawrence K. S. Wong, Craig S. Anderson, Tags: Research Source Type: research

CT Angiogram Helps to Predict Ischemic Stroke in Dizzy Patients, but NOT Better than the Clinical Examination (P3.084)
Conclusions: In patients with subjective dizziness, stroke risk factors and focal exam findings predict acute ischemic stroke. Calcification on CTA is also predictive, but does not significantly improve sensitivity.Disclosure: Dr. Chen has nothing to disclose. Dr. Schneider has nothing to disclose. Dr. Marsh has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Chen, K., Schneider, A., Marsh, E. Tags: Cerebrovascular Disease and Interventional Neurology: Hemorrhagic and Ischemic Stroke Source Type: research

Therapy with the Combination of Amlodipine and Irbesartan Has Persistent Preventative Effects on Stroke Onset Associated with BDNF Preservation on Cerebral Vessels in Hypertensive Rats
In this study, we investigated the significant beneficial effects of the combination therapy using amlodipine and irbesartan against stroke onset in hypertensive rats. The animals were fed an 8 % sodium diet and assigned to (1) vehicle, (2) amlodipine (2 mg/kg/day), (3) irbesartan (20 mg/kg/day), and (4) amlodipine + irbesartan groups. The drugs were given orally until 35 days, and incidences of stroke-related signs and mortality and blood pressure (BP) were monitored. Cerebral blood flow (CBF), brain water content, weight of the brain and left ventricle, and histological evaluations were conducted for the treated grou...
Source: Translational Stroke Research - December 23, 2014 Category: Neurology Source Type: research

Coronary Artery Calcium Score Improves the Prediction of Occult Coronary Artery Stenosis in Ischemic Stroke Patients Stroke
BackgroundCoronary heart disease is a significant cause of morbidity and mortality in stroke patients. The coronary artery calcium score (CACS) has emerged as a robust and noninvasive predictor of coronary events. We assessed the predictive ability of CACS to identify stroke patients with severe (≥50%) occult coronary artery stenosis in a stroke/transient ischemic attack population, in addition to the PRECORIS score, based on Framingham Risk Score and presence of cervicocephalic artery stenosis, which was derived and validated for that purpose.Methods and ResultsWe enrolled consecutive patients aged 45 to 75 years refer...
Source: JAHA:Journal of the American Heart Association - October 30, 2016 Category: Cardiology Authors: Beigneux, Y., Sablayrolles, J.-L., Varenne, O., Mas, J.-L., Calvet, D. Tags: Computerized Tomography (CT), Ischemic Stroke, Transient Ischemic Attack (TIA), Atherosclerosis, Coronary Artery Disease Original Research Source Type: research

Epidemiology, Pathophysiology, and Treatment of Hypertension in Ischaemic Stroke Patients
Stroke continues to be one of the leading causes of mortality and morbidity worldwide. There are 2 main types of stroke: ischaemic strokes, which are caused by obstruction of the blood vessels leading to or within the brain, and haemorrhagic strokes, which are induced by the disruption of blood vessels. Stroke is a disease of multifactorial aetiology that may develop as an end state in patients with serious vascular conditions—most notably, uncontrolled arterial hypertension—thereby necessitating the effective control of this risk factor to prevent stroke or its recurrence. This paper focuses specifically on the epidem...
Source: Journal of Stroke and Cerebrovascular Diseases - June 11, 2012 Category: Neurology Authors: Nur Fatirul Hisham, Ulvi Bayraktutan Tags: Review Articles Source Type: research

Risk of Ischemic Stroke Associated With Calcium Supplements With or Without Vitamin D: A Nested Case-Control Study Stroke
BackgroundThere is controversy surrounding the risk of ischemic stroke associated with the use of calcium supplements either in monotherapy or in combination with vitamin D.Methods and ResultsA nested case‐control study was performed with patients aged 40 to 89 years old, among whom a total of 2690 patients had a first episode of nonfatal ischemic stroke and for which 19 538 controls were randomly selected from the source population and frequency‐matched with cases for age, sex, and calendar year. Logistic regression provided the odds ratios while adjusting for confounding factors. A sensitivity analysis was performe...
Source: JAHA:Journal of the American Heart Association - May 18, 2017 Category: Cardiology Authors: de Abaȷo, F. J., Rodriguez-Martin, S., Rodriguez-Miguel, A., Gil, M. J. Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Research Source Type: research

Intakes of Potassium, Magnesium, and Calcium and Risk of Stroke Brief Reports
Conclusions— This study supports an association between high magnesium intake and a reduced stroke risk.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Sluijs, I., Czernichow, S., Beulens, J. W. J., Boer, J. M. A., van der Schouw, Y. T., Verschuren, W. M. M., Grobbee, D. E. Tags: Epidemiology Brief Reports Source Type: research

Factors Influencing Quality of Life in Stroke Patients: Focus on Eating Habits
This study aimed to identify lifestyle factors about eating habits that may affect the quality of life (QOL) in elderly stroke patients. Methods: Fifty elderly patients with a first-ever stroke were enrolled. QOL was assessed by the Stroke and Aphasia QOL Scale-39-J. Lifestyle factors about eating habits were collected using questionnaires (Questions 1-17) for the intake of salt, calcium, magnesium, potassium, taurine, fiber, and protein, and the frequency of breakfast.
Source: Journal of Stroke and Cerebrovascular Diseases - March 18, 2019 Category: Neurology Authors: Reina Chiba, Saya Tominaga, Kasumi Mikami, Maiko Kitajima, Mayumi Urushizaka, Toshiko Tomisawa, Junko Chiba, Joji Hagii, Minoru Yasujima, Tomohiro Osanai Source Type: research