Visit-to-visit blood pressure variability and classes of antihypertensive agents; associations with artery remodeling and the risk of stroke.

Visit-to-visit blood pressure variability and classes of antihypertensive agents; associations with artery remodeling and the risk of stroke.
Curr Pharm Des. 2015 Nov 12;
Authors: Nagai M, Dote K, Kato M, Sasaki S, Oda N, Kagawa E, Nakano Y, Yamane A, Kubo Y, Higashihara T, Miyauchi S, Harada W
Abstract
Recent studies have shown that visit-to-visit blood pressure (BP) variability was emerging as an independent risk factor for stroke. Although the mechanism is not fully understood, artery remodeling would be closely associated with the relationship between visit-to-visit BP variability and stroke. In addition, the class of antihypertensive agents is suggested to be an important determinant of visit-to-visit BP variability. This review article summarizes the recent literature on these topics. In the elderly hypertensives, strict BP control using calcium channel blockade would play a crucial role to prevent stroke via reducing the visit-to-visit BP variability.
PMID: 26561058 [PubMed - as supplied by publisher]

Source: Current Pharmaceutical Design - November 12, 2015 Category: Drugs & Pharmacology Authors: Nagai M, Dote K, Kato M, Sasaki S, Oda N, Kagawa E, Nakano Y, Yamane A, Kubo Y, Higashihara T, Miyauchi S, Harada W Tags: Curr Pharm Des Source Type: research